Current Appointments & Affiliations
Associate Professor of Biochemistry
·
2025 - Present
Biochemistry,
Basic Science Departments
Assistant Professor in Neurobiology
·
2017 - Present
Neurobiology,
Basic Science Departments
Assistant Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Recent Publications
Programmable protein expression using a genetically encoded m6A sensor.
Journal Article Nat Biotechnol · September 2024 The N6-methyladenosine (m6A) modification is found in thousands of cellular mRNAs and is a critical regulator of gene expression and cellular physiology. m6A dysregulation contributes to several human diseases, and the m6A methyltransferase machinery has e ... Full text Link to item CitemRNA epitranscriptomics.
Journal Article RNA · April 16, 2024 Epitranscriptomics refers to chemical changes in RNAs and includes numerous chemical types with varying stoichiometry and functions. RNA modifications are highly diverse in chemistry and respond in cell-type- and cell-state-dependent manners that enable an ... Full text Link to item CiteSimultaneous In Situ Detection of m6A-Modified and Unmodified RNAs Using DART-FISH.
Chapter · 2024 N6-methyladenosine (m6A) is an abundant mRNA modification which plays important roles in regulating RNA function and gene expression. Traditional methods for visualizing mRNAs within cells cannot distinguish m6A-modified and unmodified versions of the targ ... Full text Link to item CiteRecent Grants
Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2023 - 2026Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease
ResearchCollaborator · Awarded by National Institutes of Health · 2022 - 2026View All Grants
Education, Training & Certifications
Northwestern University ·
2010
Ph.D.