Katherine Schuver Garman

Katherine Schuver Garman
Associate Professor of Medicine

My research focuses on injury, repair, and cancer development in the gastrointestinal tract. My laboratory performs translational research with the goal of improving health of the gastrointestinal tract. Our work is based in observations from human clinical research. We use databases of esophageal and colon disease to learn more about clinical risk factors for disease. We also use pathology samples of tumors to study the gastrointestinal tract in different states: healthy, inflamed or damaged, and with cancer.

Current Appointments & Affiliations

Associate Professor of Medicine, Medicine, Gastroenterology, Medicine 2019
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2002
Affiliate of the Regeneration Next Initiative, Regeneration Next Initiative, Institutes and Centers 2016
Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2018

Contact Information

Dept Of Medicine, Durham, NC 27710
Duke Box 3913, Durham, NC 27710
(919) 684-1205

Background
Education, Training, & Certifications
- Fellow in Gastroenterology, Medicine, Duke University 2007 - 2009
- Chief Resident, Medicine, Duke University School of Medicine 2006 - 2007
- Fellow in Gastroenterology, Medicine, Duke University 2005 - 2006
- Medical Resident, Medicine, Duke University 2002 - 2005
- M.D., Duke University 2002
Duke Appointment History
- Assistant Professor of Medicine, Medicine, Gastroenterology, Medicine 2009 - 2019
- Medical Instructor in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2006 - 2007
- Instructor, Temporary in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2006
Expertise
Subject Headings
Research
Selected Grants
- The role of gastrin in esophageal submucosal gland acinar ductal metaplasia awarded by National Institutes of Health 2018 - 2023
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Genetic and Epigenetic Regulation of Intestinal Inflammation awarded by National Institutes of Health 2018 - 2022
- Duke Training Grant in Digestive Diseases and Nutrition awarded by National Institutes of Health 1988 - 2021
- Nanoplasmonics-based molecular analysis tool for molecular biomarkers of cancer awarded by National Institutes of Health 2015 - 2018
- Submucosal esophageal structures as a progenitor niche for esophageal repair awarded by National Institutes of Health 2013 - 2018
- Epigenetic Control of Intestinal Inflammation awarded by Kenneth Rainin Foundation 2016 - 2017
- Epigenetic control of intestinal inflammation awarded by Kenneth Rainin Foundation 2015 - 2016
- Development of a Porcine Model of Esophageal Injury and Repair awarded by University of North Carolina - Chapel Hill 2012 - 2014
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Ajayi, TA, Cantrell, S, Spann, A, and Garman, KS. "Barrett's esophagus and esophageal cancer: Links to microbes and the microbiome." Plos Pathogens 14, no. 12 (December 20, 2018): e1007384-null. Full Text
  - Feder, R, Posner, S, Qin, Y, Zheng, J, Chow, S-C, and Garman, KS. "Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices." Helicobacter 23, no. 6 (December 2018): e12540-null. Full Text
  - Garman, KS, and McCall, SJ. "Esophageal submucosal glands as a potential source of subsquamous intestinal metaplasia in Barrett's esophagus." Gastrointestinal Endoscopy 88, no. 1 (July 2018): 200-201. (Letter) Full Text
  - Lariviere, B, Garman, KS, Ferguson, NL, Fisher, DA, and Jokerst, NM. "Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors." Biomedical Optics Express 9, no. 3 (March 2018): 1164-1176. Full Text
  - Xiong, Z, Ren, S, Chen, H, Liu, Y, Huang, C, Zhang, YL, Odera, JO, Chen, T, Kist, R, Peters, H, Garman, K, Sun, Z, and Chen, X. "PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium." The Journal of pathology 244, no. 2 (February 2018): 164-175. Full Text
  - von Furstenberg, RJ, Li, J, Stolarchuk, C, Feder, R, Campbell, A, Kruger, L, Gonzalez, LM, Blikslager, AT, Cardona, DM, McCall, SJ, Henning, SJ, and Garman, KS. "Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation." Cellular and Molecular Gastroenterology and Hepatology 4, no. 3 (November 2017): 385-404. Full Text
  - Krüger, L, Gonzalez, LM, Pridgen, TA, McCall, SJ, von Furstenberg, RJ, Harnden, I, Carnighan, GE, Cox, AM, Blikslager, AT, and Garman, KS. "Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair." American Journal of Physiology. Gastrointestinal and Liver Physiology 313, no. 3 (September 2017): G180-G191. Full Text
  - Garman, KS. "Origin of Barrett's Epithelium: Esophageal Submucosal Glands." Cellular and Molecular Gastroenterology and Hepatology 4, no. 1 (July 2017): 153-156. Full Text
  - "Integrated genomic characterization of oesophageal carcinoma." Nature 541, no. 7636 (January 4, 2017): 169-175. Full Text
  - Garman, KS, Kruger, L, Thomas, S, Swiderska-Syn, M, Moser, BK, Diehl, AM, and McCall, SJ. "Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma." Histopathology 67, no. 6 (December 2015): 771-782. Full Text
  - Cancer Genome Atlas Research Network, . "Comprehensive molecular characterization of gastric adenocarcinoma." Nature 513, no. 7517 (September 2014): 202-209. Full Text
  - Karaca, G, Swiderska-Syn, M, Xie, G, Syn, W-K, Krüger, L, Machado, MV, Garman, K, Choi, SS, Michelotti, GA, Burkly, LC, Ochoa, B, and Diehl, AM. "TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice." Plos One 9, no. 1 (January 9, 2014): e83987-null. Full Text Open Access Copy
  - "MicroRNA expression differentiates squamous epithelium from barrett's esophagus and esophageal cancer." Digestive Diseases and Sciences 58, no. 11 (November 1, 2013): 3178-3188. Full Text
  - Garman, KS, Owzar, K, Hauser, ER, Westfall, K, Anderson, BR, Souza, RF, Diehl, AM, Provenzale, D, and Shaheen, NJ. "MicroRNA expression differentiates squamous epithelium from Barrett's esophagus and esophageal cancer." Digestive Diseases and Sciences 58, no. 11 (November 2013): 3178-3188. Full Text
  - Fang, Y, Chen, X, Bajpai, M, Verma, A, Das, KM, Souza, RF, Garman, KS, Donohoe, CL, O'Farrell, NJ, Reynolds, JV, and Dvorak, K. "Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma." Ann N Y Acad Sci 1300 (October 2013): 187-199. (Review) Full Text Link to Item
  - Peery, AF, Hoppo, T, Garman, KS, Dellon, ES, Daugherty, N, Bream, S, Sanz, AF, Davison, J, Spacek, M, Connors, D, Faulx, AL, Chak, A, Luketich, JD, Shaheen, NJ, and Jobe, BA. "Feasibility, safety, acceptability, and yield of office-based, screening transnasal esophagoscopy (with video)." Gastrointestinal Endoscopy 75, no. 5 (2012): 945-953.e2. Full Text
  - Garman, KS, and Shaheen, NJ. "Ablative therapies for Barrett's esophagus." Curr Gastroenterol Rep 13, no. 3 (June 2011): 226-239. (Review) Full Text Link to Item
  - "Colorectal Cancer Screening." (August 31, 2010): 212-218. (Chapter) Full Text
  - Garman, K, Tavakoly, B, and Gilmore, A. "UK: price-based promotions target poor." Tobacco control 19, no. 4 (2010): 264-265.
  - Tempelhof, MW, Garman, KS, Langman, MK, and Adams, MB. "Leveraging time and learning style, iPod vs. realtime attendance at a series of medicine residents conferences: a randomised controlled trial." Inform Prim Care 17, no. 2 (2009): 87-94. Link to Item
  - Ferrara, J, Gupta, D, Foster, E, Garman, K, and Stacy, M. "Extraocular muscle dystonia due to acquired (non-Wilsonian) hepatocerebral degeneration." Movement Disorders 23, no. 6 (2008): 875-878. Full Text
  - Echols, MR, Garman, KS, and Lyles, KW. "Clinical diagnostic reasoning [14]." New England Journal of Medicine 356, no. 12 (2007): 1272--. Full Text
  - Garman, KS, Jeffreys, A, Coffman, C, and Fisher, DA. "Colorectal cancer screening, comorbidity, and follow-up in elderly patients." Am J Med Sci 332, no. 4 (October 2006): 159-163. Link to Item
  - Garman, KS, McConnell, ES, and Cohen, HJ. "Inpatient care for elderly cancer patients: the role for Geriatric Evaluation and Management Units in fulfilling goals for care." Critical Reviews in Oncology/Hematology 51, no. 3 (September 2004): 241-247. Full Text
  - Garman, KS, Pieper, CF, Seo, P, and Cohen, HJ. "Function in elderly cancer survivors depends on comorbidities." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 58, no. 12 (December 2003): M1119-M1124. Full Text
  - Garman, KS, and Cohen, HJ. "Functional status and the elderly cancer patient." Crit Rev Oncol Hematol 43, no. 3 (September 2002): 191-208. (Review) Link to Item
- Conference Papers
  - Zhang, X, Zhao, L, Guy, CD, McCall, SJ, Cardona, DM, Burbridge, RA, Garman, KS, Branch, MS, Siddiqui, U, Xiao, S-Y, Waxman, I, and Hart, J. "Delayed Specimen Collection May Artifactually Damage the Mucosal Surface in Barrett's EMR Specimens." February 2014. Link to Item
  - Tucker, A, Michelotti, GA, Choi, SS, Xie, G, Karaca, G, Swiderska-Syn, M, Kruger, L, Machado, MV, Garman, KS, and Diehl, AM. "The Role of Pleiotrophin Signaling in the Hepatic Stem Cell Niche." October 2013. Link to Item
  - Garman, KS, Jeffreys, A, and Fisher, D. "Colorectal cancer screening and follow-up in the elderly." October 2004. Link to Item

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Education, Training, & Certifications

Duke Appointment History

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Conference Papers