Skip to main content

Kevin J Wiehe

Norman L. Letvin Associate Professor in Medicine
Medicine, Duke Human Vaccine Institute
106 Research Dr, MSRBII Box 103020, Durham, NC 27710

Selected Grants


Persistent Immunogenicity of IDLV delivering membrane tethered Native-Like HIV-1 Envelope Trimers

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2025 - 2030

Translating germline-targeting HIV Env SOSIP immunization of infants: targeting bnAbs in early life

ResearchPrincipal Investigator · Awarded by Weill Cornell Medicine · 2025 - 2030

Genetic and Structural Basis for Virus Neutralization

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

DMS/NIGMS 1: Challenges in Stochastic Modeling and Computation for Sequential Vaccine Design

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2024 - 2027

SHIV/HIV Env-antibody coevolution as a molecular guide to V3 glycan targeted vaccine design

ResearchPrincipal Investigator · Awarded by University of Pennsylvania · 2022 - 2027

CIVICs Component A Year 7 - Option 6

ResearchBioinformatics & Data Mgmt Core Head · Awarded by National Institutes of Health · 2019 - 2026

Evaluation of Antibody Responses Elicited by Zika Vaccination in Flavivirus-naive and -experienced Individuals

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2023 - 2026

HIVRAD Project 1: Age-related impact on early life B cell lineage-designed SOSIP HIV Env vaccination

ResearchPrincipal Investigator · Awarded by Weill Cornell Medicine · 2020 - 2026

Natural killer cell regulation of the germinal center HIV neutralizing antibody response

ResearchCo Investigator · Awarded by The Children's Mercy Hospital · 2019 - 2025

Duke DARPA Pandemic Prevention Platform (P3)

ResearchInvestigator · Awarded by Defense Advanced Research Projects Agency · 2017 - 2024

Immunogen Design of HIV Sequential Envelopes Derived from SHIV-infected Macaques

ResearchInvestigator · Awarded by University of Pennsylvania · 2017 - 2023

Combined Hepatitis B and HIV-1 Envelope Infant Vaccination to Augment T cell Help through Enhanced Linked Recognition

ResearchBioinformatics Specialist · Awarded by National Institutes of Health · 2017 - 2022

Immunogen Design Strategies To Direct Hiv-1 Broadly Neutralizing Antibody Maturation By Probability-Based Targeting Of Critical Mutations

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2021

Project 2: RNA vaccination in early life to induce potent and broad HIV Env-specific antibody responses

ResearchInvestigator · Awarded by Weill Cornell Medicine · 2020 - 2021

Validation of the ADAMANT Platform

ResearchInvestigator · Awarded by Ology Bioservices · 2019 - 2020

Natural killer cell regulation of the germinal center HIV neutralizing antibody response

ResearchCo Investigator · Awarded by The Children's Mercy Hospital · 2019 - 2019

Creation of a bnAbnectin

ResearchInvestigator · Awarded by ViiV Healthcare · 2017 - 2019

Critical domains for HIV-1 entry through atypical coreceptor usage

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2016