Scholars@Duke
Kevin Williams

Kevin Williams

Assistant Professor of Pediatrics
Pediatrics, Neonatology
kevin.williams@duke.edu
2400 Pratt St., Durham, NC 27705
2400 Pratt St., Durham, NC 27705
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Selected Publications

Chorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates.

Journal Article J Neuroinflammation · January 10, 2024 BACKGROUND: Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of disrupted cerebellar development i ... Full text Link to item Cite

Extracellular vesicles: pathogenic messengers and potential therapy for neonatal lung diseases

Journal Article Frontiers in Pediatrics · July 11, 2023 Extracellular vesicles (EVs) are a heterogeneous group of nano-sized membranous structures increasingly recognized as mediators of intercellular and inter-organ communication. EVs contain a cargo of proteins, lipids and nucleic acids, and their cargo compo ... Full text Cite

Cell-based therapy to boost right ventricular function and cardiovascular performance in hypoplastic left heart syndrome: Current approaches and future directions.

Journal Article Semin Perinatol · April 2023 Congenital heart disease remains one of the most frequently diagnosed congenital diseases of the newborn, with hypoplastic left heart syndrome (HLHS) being considered one of the most severe. This univentricular defect was uniformly fatal until the introduc ... Full text Link to item Cite

Mesenchymal Stem Cell-derived Extracellular Vesicles Prevent Experimental Bronchopulmonary Dysplasia Complicated By Pulmonary Hypertension.

Journal Article Stem Cells Transl Med · August 23, 2022 Mesenchymal stem cell (MSC) extracellular vesicles (EVs) have beneficial effects in preclinical bronchopulmonary dysplasia and pulmonary hypertension (BPD-PH) models. The optimal source, dosing, route, and duration of effects are however unknown. The objec ... Full text Open Access Link to item Cite

Amniotic fluid-derived extracellular vesicles: characterization and therapeutic efficacy in an experimental model of bronchopulmonary dysplasia.

Journal Article Cytotherapy · December 2021 BACKGROUND AIMS: Extracellular vesicles (EVs) are being tested for their use as novel therapeutics. However, the optimal source of EVs is currently under investigation. Amniotic fluid (AF) is a natural source of EVs that can be easily obtained for use in r ... Full text Link to item Cite