Kingshuk Roy Choudhury | Scholars@Duke

Kingshuk Roy Choudhury
Associate Professor of Biostatistics and Bioinformatics

Statistical modelling, data analysis.
Analysis of multiple observer studies.
Analysis of complex data.
Modelling tumor growth. Translation in drug discovery.
Statistical analysis of images: cellular and medical imaging.
Statistics of shape, structure and spatial arrangement.

Current Appointments & Affiliations

Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2013
Associate Professor of Radiology, Radiology, Clinical Science Departments 2013

Contact Information

2424 Erwin Road Suite 302, 3063 Hock Plaza, Durham, NC 27705
Duke Box 2721, Durham, NC 27710
kingshuk@duke.edu (919) 684-1450

Background
Education, Training, & Certifications
- Ph.D., University of Washington 1998
Duke Appointment History
- Associate Professor of Radiology, Radiology, Clinical Science Departments 2011 - 2013
Expertise
Subject Headings
Global Scholarship
- Research
  - Ireland (Country)
Research
Selected Grants
- Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health 2017 - 2021
- Non-invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe MRI awarded by National Institutes of Health 2016 - 2019
- Health Care Systems Research Collaboratory - Coordinating Center awarded by National Institutes of Health 2012 - 2018
- Human Lung Regional Ventilation Defect Severity Measured by Fluorine-19 Gas MRI awarded by National Institutes of Health 2012 - 2018
- Heat and Radiation Effects on Tumor Microcirculation awarded by National Institutes of Health 1985 - 2015
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Solomon, J, Rubin, G, Smith, T, Harrawood, B, Choudhury, KR, and Samei, E. "Development of local complexity metrics to quantify the effect of anatomical noise on detectability of lung nodules in chest CT imaging." January 1, 2017. Full Text
  - Zheng, Y, Solomon, J, Choudhury, K, Marin, D, and Samei, E. "Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions." January 1, 2017. Full Text
  - Huang, J, Wolsztynski, E, Hawe, D, Kim, KM, Roy Choudhury, K, and O'Sullivan, F. "A cautionary note on the use of positivity constrained reconstructions for quantification of regional PET imaging data." January 1, 2013. Full Text
  - Das, S, Hoang, J, Choudhury, KR, Yoo, D, and Brizel, D. "WE-A-217A-02: The Impact of Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Variability on the Assessment of Treatment Response in Head-And-Neck Cancer Patients Undergoing Chemoradiotherapy." June 2012. Full Text
- Journal Articles
  - Marin, D, Davis, D, Roy Choudhury, K, Patel, B, Gupta, RT, Mileto, A, and Nelson, RC. "Characterization of Small Focal Renal Lesions: Diagnostic Accuracy with Single-Phase Contrast-enhanced Dual-Energy CT with Material Attenuation Analysis Compared with Conventional Attenuation Measurements." Radiology 284, no. 3 (September 2017): 737-747. Full Text
  - Sofue, K, Burke, LMB, Nilmini, V, Alagiyawanna, M, Muir, AJ, Choudhury, KR, Jaffe, TA, Semelka, RC, and Bashir, MR. "Liver imaging reporting and data system category 4 observations in MRI: Risk factors predicting upgrade to category 5. (Accepted)" Journal of magnetic resonance imaging : JMRI 46, no. 3 (September 2017): 783-792. Full Text
  - Solomon, J, Marin, D, Roy Choudhury, K, Patel, B, and Samei, E. "Effect of Radiation Dose Reduction and Reconstruction Algorithm on Image Noise, Contrast, Resolution, and Detectability of Subtle Hypoattenuating Liver Lesions at Multidetector CT: Filtered Back Projection versus a Commercial Model-based Iterative Reconstruction Algorithm." Radiology 284, no. 3 (September 2017): 777-787. Full Text
  - Lee, C-T, Zhou, Y, Roy-Choudhury, K, Siamakpour-Reihani, S, Young, K, Hoang, P, Kirkpatrick, JP, Chi, J-TA, Dewhirst, MW, and Horton, JK. "Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer." Radiation research 188, no. 2 (August 2017): 169-180. Full Text
  - Lin, C, Vakani, R, Kussin, P, Guhwe, M, Farjat, AE, Choudhury, K, Renner, D, Oduor, C, Graffagnino, C, and Neuroscience Knowledge Base Investigator Group, . "Assessment of healthcare personnel knowledge of stroke care at a large referral hospital in sub-Saharan Africa - A survey based approach." Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 42 (August 2017): 71-74. Full Text
  - Birer, SR, Lee, C-T, Choudhury, KR, Young, KH, Spasojevic, I, Batinic-Haberle, I, Crapo, JD, Dewhirst, MW, and Ashcraft, KA. "Inhibition of the Continuum of Radiation-Induced Normal Tissue Injury by a Redox-Active Mn Porphyrin." Radiation research 188, no. 1 (July 2017): 94-104. Full Text
  - Ebner, L, Tall, M, Choudhury, KR, Ly, DL, Roos, JE, Napel, S, and Rubin, GD. "Variations in the functional visual field for detection of lung nodules on chest computed tomography: Impact of nodule size, distance, and local lung complexity." Medical physics 44, no. 7 (July 2017): 3483-3490. Full Text
  - Carico, ZM, Roy Choudhury, K, Zhang, B, Zhuang, Y, and Krangel, MS. "Tcrd Rearrangement Redirects a Processive Tcra Recombination Program to Expand the Tcra Repertoire." Cell reports 19, no. 10 (June 2017): 2157-2173. Full Text
  - Lin, C, Loochtan, AI, Dresser, B, Chang, J, Farjat, AE, Choudhury, K, and Hobson-Webb, LD. "Is carpal tunnel syndrome present in acute stroke patients? An investigative study using clinical and imaging screening tools." Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 39 (May 2017): 111-113. Full Text
  - Kranz, PG, Joshi, AB, Roy, LA, Choudhury, KR, and Amrhein, TJ. "Inadvertent Intrafacet Injection during Lumbar Interlaminar Epidural Steroid Injection: A Comparison of CT Fluoroscopic and Conventional Fluoroscopic Guidance." AJNR. American journal of neuroradiology 38, no. 2 (February 2017): 398-402. Full Text
  - Kranz, PG, Amrhein, TJ, Choudhury, KR, Tanpitukpongse, TP, and Gray, L. "Time-Dependent Changes in Dural Enhancement Associated With Spontaneous Intracranial Hypotension." AJR. American journal of roentgenology 207, no. 6 (December 2016): 1283-1287. Full Text
  - Ikejimba, LC, Glick, SJ, Choudhury, KR, Samei, E, and Lo, JY. "Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms." Medical physics 43, no. 10 (October 2016): 5593-. Full Text
  - Burke, LMB, Sofue, K, Alagiyawanna, M, Nilmini, V, Muir, AJ, Choudhury, KR, Semelka, RC, and Bashir, MR. "Natural history of liver imaging reporting and data system category 4 nodules in MRI." Abdominal radiology (New York) 41, no. 9 (September 2016): 1758-1766. Full Text
  - Toffaletti, JG, Hammett-Stabler, CA, Gearhart, M, Roy Choudhury, K, and Handel, EA. "The analytical change in plasma creatinine that constitutes a biologic/physiologic change." Clinica chimica acta; international journal of clinical chemistry 459 (August 2016): 79-83. Full Text
  - Makar, RA, Bashir, MR, Haystead, CM, Iseman, C, Mayes, N, Hebert, S, Allen, BC, Bhattacharya, SD, Choudhury, KR, and Jaffe, TA. "Diagnostic performance of MDCT in identifying closed loop small bowel obstruction." Abdominal radiology (New York) 41, no. 7 (July 2016): 1253-1260. Full Text
  - Bag, S, Prentice, MB, Liang, M, Warren, MJ, and Roy Choudhury, K. "Classification of polyhedral shapes from individual anisotropically resolved cryo-electron tomography reconstructions." BMC bioinformatics 17, no. 1 (June 13, 2016): 234-. Full Text
  - Weitzel, DH, Tovmasyan, A, Ashcraft, KA, Boico, A, Birer, SR, Roy Choudhury, K, Herndon, J, Rodriguiz, RM, Wetsel, WC, Peters, KB, Spasojevic, I, Batinic-Haberle, I, and Dewhirst, MW. "Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier." Environmental and molecular mutagenesis 57, no. 5 (June 2016): 372-381. Full Text
  - Bushey, RT, Moody, MA, Nicely, NL, Haynes, BF, Alam, SM, Keir, ST, Bentley, RC, Roy Choudhury, K, Gottlin, EB, Campa, MJ, Liao, H-X, and Patz, EF. "A Therapeutic Antibody for Cancer, Derived from Single Human B Cells." Cell reports 15, no. 7 (May 4, 2016): 1505-1513. Full Text Open Access Copy
  - Howard, BA, Roy Choudhury, K, Oldan, JD, Pagnanelli, RA, and Borges-Neto, S. "Difference in appearance between prone and supine myocardial perfusion images obtained on a high-efficiency cadmium zinc telluride SPECT camera." Nuclear medicine communications 37, no. 5 (May 2016): 487-492. Full Text
  - Ghosh, M, Roy, K, Das Mukherjee, D, Chakrabarti, G, Roy Choudhury, K, and Roy, S. "Correction: Leishmania donovani Infection Enhances Lateral Mobility of Macrophage Membrane Protein Which Is Reversed by Liposomal Cholesterol." PLoS neglected tropical diseases 10, no. 4 (April 13, 2016): e0004640-. Full Text
  - Mileto, A, Barina, A, Marin, D, Stinnett, SS, Roy Choudhury, K, Wilson, JM, and Nelson, RC. "Virtual Monochromatic Images from Dual-Energy Multidetector CT: Variance in CT Numbers from the Same Lesion between Single-Source Projection-based and Dual-Source Image-based Implementations." Radiology 279, no. 1 (April 2016): 269-277. Full Text
  - Prescott, JW, Guidon, A, Doraiswamy, PM, Choudhury, KR, Liu, C, and Petrella, JR. "Erratum: The Alzheimer Structural Connectome: Changes in Cortical Network Topology with Increased Amyloid Plaque Burden (Radiology (2014) 273:1 (175-184) DOI: 10.1148/radiol.14132593)." Radiology 279, no. 1 (April 1, 2016): 328-. Full Text
  - Solomon, J, Mileto, A, Nelson, RC, Roy Choudhury, K, and Samei, E. "Quantitative Features of Liver Lesions, Lung Nodules, and Renal Stones at Multi-Detector Row CT Examinations: Dependency on Radiation Dose and Reconstruction Algorithm." Radiology 279, no. 1 (April 2016): 185-194. Full Text
  - Brinkley, MF, Ramirez-Giraldo, JC, Samei, E, Frush, DJ, Choudhury, KR, Wilson, JM, Christianson, OI, and Frush, DP. "Effects of automatic tube potential selection on radiation dose index, image quality, and lesion detectability in pediatric abdominopelvic CT and CTA: a phantom study." European radiology 26, no. 1 (January 2016): 157-166. Full Text
  - Ashcraft, KA, Boss, M-K, Tovmasyan, A, Roy Choudhury, K, Fontanella, AN, Young, KH, Palmer, GM, Birer, SR, Landon, CD, Park, W, Das, SK, Weitner, T, Sheng, H, Warner, DS, Brizel, DM, Spasojevic, I, Batinic-Haberle, I, and Dewhirst, MW. "Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model." International journal of radiation oncology, biology, physics 93, no. 4 (November 2015): 892-900. Full Text
  - Adam, MA, Choudhury, K, Goffredo, P, Reed, SD, Blazer, D, Roman, SA, and Sosa, JA. "Minimally Invasive Distal Pancreatectomy for Cancer: Short-Term Oncologic Outcomes in 1,733 Patients." World journal of surgery 39, no. 10 (October 2015): 2564-2572. Full Text
  - Gardner, CS, Bashir, MR, Marin, D, Nelson, RC, Choudhury, KR, and Ho, LM. "Diagnostic performance of imaging criteria for distinguishing autoimmune cholangiopathy from primary sclerosing cholangitis and bile duct malignancy." Abdominal imaging 40, no. 8 (October 2015): 3052-3061. Full Text
  - Marin, D, Mileto, A, Gupta, RT, Ho, LM, Allen, BC, Choudhury, KR, and Nelson, RC. "Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality." Abdominal imaging 40, no. 7 (October 2015): 2850-2860. Full Text
  - Mileto, A, Ramirez-Giraldo, JC, Nelson, RC, Hurwitz, LM, Choudhury, KR, Seaman, DM, and Marin, D. "High-Pitch Dual-Source MDCT for Imaging of the Thoracoabdominal Aorta: Relationships Among Radiation Dose, Noise, Pitch, and Body Size in a Phantom Experiment and Clinical Study." AJR. American journal of roentgenology 205, no. 4 (October 2015): 834-839. Full Text
  - Lin, KA, Choudhury, KR, Rathakrishnan, BG, Marks, DM, Petrella, JR, Doraiswamy, PM, and Alzheimer's Disease Neuroimaging Initiative, . "Marked gender differences in progression of mild cognitive impairment over 8 years." Alzheimer's & dementia (New York, N. Y.) 1, no. 2 (September 2015): 103-110. Full Text
  - Adam, MA, Choudhury, K, Dinan, MA, Reed, SD, Scheri, RP, Blazer, DG, Roman, SA, and Sosa, JA. "Minimally Invasive Versus Open Pancreaticoduodenectomy for Cancer: Practice Patterns and Short-term Outcomes Among 7061 Patients." Annals of surgery 262, no. 2 (August 2015): 372-377. Full Text
  - Choudhury, KR, Keir, ST, Ashcraft, KA, Boss, M-K, and Dewhirst, MW. "Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies." Oncotarget 6, no. 16 (June 2015): 14656-14668.
  - Osada, T, Nagaoka, K, Takahara, M, Yang, XY, Liu, C-X, Guo, H, Roy Choudhury, K, Hobeika, A, Hartman, Z, Morse, MA, and Lyerly, HK. "Precision cancer immunotherapy: optimizing dendritic cell-based strategies to induce tumor antigen-specific T-cell responses against individual patient tumors." Journal of immunotherapy (Hagerstown, Md. : 1997) 38, no. 4 (May 2015): 155-164. Full Text
  - Grady, AT, Sosa, JA, Tanpitukpongse, TP, Choudhury, KR, Gupta, RT, and Hoang, JK. "Radiology reports for incidental thyroid nodules on CT and MRI: high variability across subspecialties." AJNR. American journal of neuroradiology 36, no. 2 (February 2015): 397-402. Full Text
  - Huang, EP, Wang, X-F, Choudhury, KR, McShane, LM, Gönen, M, Ye, J, Buckler, AJ, Kinahan, PE, Reeves, AP, Jackson, EF, Guimaraes, AR, Zahlmann, G, and Meta-Analysis Working Group, . "Meta-analysis of the technical performance of an imaging procedure: guidelines and statistical methodology." Statistical methods in medical research 24, no. 1 (February 2015): 141-174. (Review) Full Text
  - Kessler, LG, Barnhart, HX, Buckler, AJ, Choudhury, KR, Kondratovich, MV, Toledano, A, Guimaraes, AR, Filice, R, Zhang, Z, Sullivan, DC, and QIBA Terminology Working Group, . "The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions." Statistical methods in medical research 24, no. 1 (February 2015): 9-26. Full Text
  - Mileto, A, Nelson, RC, Marin, D, Roy Choudhury, K, and Ho, LM. "Dual-energy multidetector CT for the characterization of incidental adrenal nodules: diagnostic performance of contrast-enhanced material density analysis." Radiology 274, no. 2 (February 2015): 445-454. Full Text
  - Garcia-Reyes, K, Passoni, NM, Palmeri, ML, Kauffman, CR, Choudhury, KR, Polascik, TJ, and Gupta, RT. "Detection of prostate cancer with multiparametric MRI (mpMRI): effect of dedicated reader education on accuracy and confidence of index and anterior cancer diagnosis." Abdominal imaging 40, no. 1 (January 2015): 134-142. Full Text
  - Rubin, GD, Roos, JE, Tall, M, Harrawood, B, Bag, S, Ly, DL, Seaman, DM, Hurwitz, LM, Napel, S, and Roy Choudhury, K. "Characterizing search, recognition, and decision in the detection of lung nodules on CT scans: elucidation with eye tracking." Radiology 274, no. 1 (January 2015): 276-286. Full Text
  - Ghosh, M, Roy, K, Das Mukherjee, D, Chakrabarti, G, Roy Choudhury, K, and Roy, S. "Leishmania donovani infection enhances lateral mobility of macrophage membrane protein which is reversed by liposomal cholesterol." PLoS neglected tropical diseases 8, no. 12 (December 4, 2014): e3367-. Full Text
  - Mileto, A, Nelson, RC, Samei, E, Choudhury, KR, Jaffe, TA, Wilson, JM, and Marin, D. "Dual-energy MDCT in hypervascular liver tumors: effect of body size on selection of the optimal monochromatic energy level." AJR. American journal of roentgenology 203, no. 6 (December 2014): 1257-1264. Full Text
  - Shpanskaya, KS, Choudhury, KR, Hostage, C, Murphy, KR, Petrella, JR, Doraiswamy, PM, and Alzheimer's Disease Neuroimaging Initiative, . "Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort." Journal of neuroradiology. Journal de neuroradiologie 41, no. 5 (December 2014): 350-357. Full Text
  - Shpanskaya, KS, Choudhury, KR, Hostage, C, Murphy, KR, Petrella, JR, and Doraiswamy, PM. "Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort." Journal of Neuroradiology 41, no. 5 (December 1, 2014): 350-357. Full Text
  - Hoang, JK, Choudhury, KR, Chang, J, Craciunescu, OI, Yoo, DS, and Brizel, DM. "Diffusion-weighted imaging for head and neck squamous cell carcinoma: quantifying repeatability to understand early treatment-induced change." AJR. American journal of roentgenology 203, no. 5 (November 2014): 1104-1108. Full Text
  - Samei, E, Lin, Y, Choudhury, KR, and McAdams, HP. "Automated characterization of perceptual quality of clinical chest radiographs: validation and calibration to observer preference." Medical physics 41, no. 11 (November 2014): 111918-. Full Text
  - Prescott, JW, Guidon, A, Doraiswamy, PM, Roy Choudhury, K, Liu, C, Petrella, JR, and Alzheimer’s Disease Neuroimaging Initiative, . "The Alzheimer structural connectome: changes in cortical network topology with increased amyloid plaque burden." Radiology 273, no. 1 (October 2014): 175-184. Full Text
  - Marin, D, Fananapazir, G, Mileto, A, Choudhury, KR, Wilson, JM, and Nelson, RC. "Dual-energy multi-detector row CT with virtual monochromatic imaging for improving patient-to-patient uniformity of aortic enhancement during CT angiography: an in vitro and in vivo study." Radiology 272, no. 3 (September 2014): 895-902. Full Text
  - Mileto, A, Nelson, RC, Samei, E, Jaffe, TA, Paulson, EK, Barina, A, Choudhury, KR, Wilson, JM, and Marin, D. "Impact of dual-energy multi-detector row CT with virtual monochromatic imaging on renal cyst pseudoenhancement: in vitro and in vivo study." Radiology 272, no. 3 (September 2014): 767-776. Full Text
  - Bahl, M, Sosa, JA, Nelson, RC, Esclamado, RM, Choudhury, KR, and Hoang, JK. "Trends in incidentally identified thyroid cancers over a decade: a retrospective analysis of 2,090 surgical patients." World J Surg 38, no. 6 (June 2014): 1312-1317. Full Text Link to Item
  - Preece, SR, Schriber, SM, Choudhury, KR, Suhocki, PV, Smith, TP, and Kim, CY. "Coil embolization of the splenic artery: impact on splenic volume." Journal of vascular and interventional radiology : JVIR 25, no. 6 (June 2014): 859-865. Full Text
  - Hoang, JK, Choudhury, KR, Eastwood, JD, Esclamado, RM, Lyman, GH, Shattuck, TM, and Nguyen, XV. "An exponential growth in incidence of thyroid cancer: trends and impact of CT imaging." AJNR Am J Neuroradiol 35, no. 4 (April 2014): 778-783. Full Text Link to Item
  - Hostage, CA, Choudhury, KR, Murali Doraiswamy, P, Petrella, JR, and Alzheimer's Disease Neuroimaging Initiative, . "Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network." Radiology 271, no. 1 (April 2014): 211-219. Full Text
  - Bahl, M, Muzaffar, M, Vij, G, Sosa, JA, Choudhury, KR, and Hoang, JK. "Prevalence of the polar vessel sign in parathyroid adenomas on the arterial phase of 4D CT." AJNR Am J Neuroradiol 35, no. 3 (March 2014): 578-581. Full Text Link to Item
  - Subashi, E, Choudhury, KR, and Johnson, GA. "An analysis of the uncertainty and bias in DCE-MRI measurements using the spoiled gradient-recalled echo pulse sequence." Medical physics 41, no. 3 (March 2014): 032301-. Full Text
  - Bahl, M, Sosa, JA, Nelson, RC, Esclamado, RM, Choudhury, KR, and Hoang, JK. "Trends in incidentally identified thyroid cancers over a decade: A retrospective analysis of 2,090 surgical patients." World Journal of Surgery 38, no. 6 (January 1, 2014): 1312-1317. Full Text
  - Huber, A, Ebner, L, Montani, M, Semmo, N, Choudhury, KR, Heverhagen, J, and Christe, A. "Computed tomography findings in liver fibrosis and cirrhosis." Swiss medical weekly 144 (2014): w13923-. Full Text
  - Huber, A, Ebner, L, Montani, M, Semmo, N, Roy Choudhury, K, Heverhagen, J, and Christe, A. "Computed tomography findings in liver fibrosis and cirrhosis." Swiss medical weekly 144 (January 2014): w13923-. Full Text
  - Lampert, EJ, Roy Choudhury, K, Hostage, CA, Rathakrishnan, B, Weiner, M, Petrella, JR, Doraiswamy, PM, and Alzheimer's Disease Neuroimaging Initiative, . "Brain atrophy rates in first degree relatives at risk for Alzheimer's." NeuroImage. Clinical 6 (January 2014): 340-346. Full Text
  - Lin, Y, Choudhury, KR, McAdams, HP, Foos, DH, and Samei, E. "Validation of an image-based technique to assess the perceptual quality of clinical chest radiographs with an observer study." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 9033 (January 1, 2014). Full Text
  - Preece, SR, Schriber, SM, Choudhury, KR, Suhocki, PV, Smith, TP, and Kim, CY. "Coil embolization of the splenic artery: Impact on splenic volume." Journal of Vascular and Interventional Radiology 25, no. 6 (January 1, 2014): 859-865. Full Text
  - Marin, D, Choudhury, KR, Gupta, RT, Ho, LM, Allen, BC, Schindera, ST, Colsher, JG, Samei, E, and Nelson, RC. "Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique." European Radiology 23, no. 12 (December 1, 2013): 3325-3335. Full Text
  - Marin, D, Choudhury, KR, Gupta, RT, Ho, LM, Allen, BC, Schindera, ST, Colsher, JG, Samei, E, and Nelson, RC. "Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique." Eur Radiol 23, no. 12 (December 2013): 3325-3335. Full Text Link to Item
  - Spritzer, CE, Afonso, PD, Vinson, EN, Turnbull, JD, Morris, KK, Foye, A, Madden, JF, Roy Choudhury, K, Febbo, PG, and George, DJ. "Bone marrow biopsy: RNA isolation with expression profiling in men with metastatic castration-resistant prostate cancer--factors affecting diagnostic success." Radiology 269, no. 3 (December 2013): 816-823. Full Text Link to Item
  - Chan, EAW, Teng, G, Corbett, E, Choudhury, KR, Bassing, CH, Schatz, DG, and Krangel, MS. "Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2." Proc Natl Acad Sci U S A 110, no. 48 (November 26, 2013): E4628-E4637. Full Text Link to Item
  - Boyce, SJ, Choudhury, KR, and Samei, E. "Effective DQE (eDQE) for monoscopic and stereoscopic chest radiography imaging systems with the incorporation of anatomical noise." Med Phys 40, no. 9 (September 2013): 091916-. Full Text Link to Item
  - Murphy, KR, Landau, SM, Choudhury, KR, Hostage, CA, Shpanskaya, KS, Sair, HI, Petrella, JR, Wong, TZ, Doraiswamy, PM, and Alzheimer's Disease Neuroimaging Initiative, . "Mapping the effects of ApoE4, age and cognitive status on 18F-florbetapir PET measured regional cortical patterns of beta-amyloid density and growth." Neuroimage 78 (September 2013): 474-480. Full Text Link to Item
  - Nguyen, XV, Choudhury, KR, Eastwood, JD, Lyman, GH, Esclamado, RM, Werner, JD, and Hoang, JK. "Incidental thyroid nodules on CT: evaluation of 2 risk-categorization methods for work-up of nodules." AJNR Am J Neuroradiol 34, no. 9 (September 2013): 1812-1817. Full Text Link to Item
  - Hoang, JK, Das, SK, Choudhury, KR, Yoo, DS, and Brizel, DM. "Using FDG-PET to measure early treatment response in head and neck squamous cell carcinoma: quantifying intrinsic variability in order to understand treatment-induced change." AJNR Am J Neuroradiol 34, no. 7 (July 2013): 1428-1433. Full Text Link to Item
  - Nelson, KP, Choudhury, KR, Coleman, RE, Shipes, SW, Siler, WL, Hubble, WL, and Wong, TZ. "Does the preparation and utilization of 99mTc-sulfur colloid affect the outcomes of breast lymphoscintigraphy?." J Nucl Med Technol 41, no. 2 (June 2013): 92-98. Full Text Link to Item
  - Shaffer, JL, Petrella, JR, Sheldon, FC, Choudhury, KR, Calhoun, VD, Coleman, RE, Doraiswamy, PM, and Alzheimer’s Disease Neuroimaging Initiative, . "Predicting cognitive decline in subjects at risk for Alzheimer disease by using combined cerebrospinal fluid, MR imaging, and PET biomarkers." Radiology 266, no. 2 (February 2013): 583-591. Full Text Link to Item
  - Christe, A, Charimo-Torrente, J, Roychoudhury, K, Vock, P, and Roos, JE. "Accuracy of low-dose computed tomography (CT) for detecting and characterizing the most common CT-patterns of pulmonary disease." European Journal of Radiology 82, no. 3 (2013): e142-e150. Full Text
  - Christe, A, Ebner, L, Steiger, P, Parikh, SR, Shah, AD, Roychoudhury, K, Vock, P, and Roos, JE. "Impact of image quality, radiologists, lung segments, and gunnar eyewear on detectability of lung nodules in chest CT." Acta Radiologica 54, no. 6 (2013): 646-651. Full Text
  - Christe, A, Lin, MC, Yen, AC, Hallett, RL, Roychoudhury, K, Schmitzberger, F, Fleischmann, D, Leung, AN, Rubin, GD, Vock, P, and Roos, JE. "Erratum: CT patterns of fungal pulmonary infections of the lung: Comparison of standard-dose and simulated low-dose CT (European Journal of Radiology (2012) 81 (2860-2866))." European Journal of Radiology 82, no. 11 (2013): 2067--. Full Text
  - Christe, A, Lin, MC, Yen, AC, Hallett, RL, Roychoudhury, K, Schmitzberger, F, Fleischmann, D, Leung, AN, Rubin, GD, Vock, P, and al, E. "Corrigendum to 'CT patterns of fungal pulmonary infections of the lung: Comparison of standard-dose and simulated low-dose CT' [Eur. J. Radiol. 81 (2012) 2860-2866] (DOI:10.1016/j.ejrad.2011.06.059)." European Journal of Radiology (2013). Full Text
  - Hostage, CA, Roy Choudhury, K, Doraiswamy, PM, Petrella, JR, and Alzheimer’s Disease Neuroimaging Initiative, . "Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease." PLoS One 8, no. 2 (2013): e54483-. Full Text Link to Item
  - Lampert, EJ, Roy Choudhury, K, Hostage, CA, Petrella, JR, Doraiswamy, PM, and Alzheimer’s Disease Neuroimaging Initiative, . "Prevalence of Alzheimer's pathologic endophenotypes in asymptomatic and mildly impaired first-degree relatives. (Published online)" PLoS One 8, no. 4 (2013): e60747-. Full Text Link to Item
  - Roy Choudhury, K, O'Sullivan, F, Kasman, I, and Plowman, GD. "A comparison of least squares and conditional maximum likelihood estimators under volume endpoint censoring in tumor growth experiments." Stat Med 31, no. 29 (December 20, 2012): 4061-4073. Full Text Link to Item
  - Schauberger, JS, Kranz, PG, Choudhury, KR, Eastwood, JD, Gray, L, and Hoang, JK. "CT-guided lumbar nerve root injections: are we using the correct radiation dose settings?." AJNR Am J Neuroradiol 33, no. 10 (November 2012): 1855-1859. Full Text Link to Item
  - Christe, A, Lin, MC, Yen, AC, Hallett, RL, Roychoudhury, K, Schmitzberger, F, Fleischmann, D, Leung, AN, Rubin, GD, Vock, P, and Roos, JE. "CT patterns of fungal pulmonary infections of the lung: comparison of standard-dose and simulated low-dose CT." Eur J Radiol 81, no. 10 (October 2012): 2860-2866. Full Text Link to Item
  - Roy Choudhury, K, and Gibson, R. "Reproducible research in medical imaging." Mol Imaging Biol 14, no. 4 (August 2012): 395-396. Full Text Link to Item
  - Choudhury, KR, Tian, R, Li, X, and Samei, E. "SU-E-I-47: Comparison of Risks for Two Medical Imaging Procedures." Medical physics 39, no. 6Part4 (June 2012): 3635-. Full Text
  - Hoang, JK, Yoshizumi, TT, Choudhury, KR, Nguyen, GB, Toncheva, G, Gafton, AR, Eastwood, JD, Lowry, C, and Hurwitz, LM. "Organ-based dose current modulation and thyroid shields: techniques of radiation dose reduction for neck CT." AJR Am J Roentgenol 198, no. 5 (May 2012): 1132-1138. Full Text Link to Item
  - Hoang, JK, Yoshizumi, TT, Nguyen, G, Toncheva, G, Choudhury, KR, Gafton, AR, Eastwood, JD, Lowry, C, and Hurwitz, LM. "Variation in tube voltage for adult neck MDCT: effect on radiation dose and image quality." AJR Am J Roentgenol 198, no. 3 (March 2012): 621-627. Full Text Link to Item
  - Tall, M, Choudhury, KR, Napel, S, Roos, JE, and Rubin, GD. "Accuracy of a remote eye tracker for radiologic observer studies: effects of calibration and recording environment." Acad Radiol 19, no. 2 (February 2012): 196-202. Full Text Link to Item
  - Choudhury, KR, and Pettigrew, C. "Parametric scalp mapping and inference via spatially smooth linear models for mismatch negativity studies." Journal of Statistical Planning and Inference 142, no. 1 (2012): 12-24. Full Text
  - Christe, A, Charimo-Torrente, J, Roychoudhury, K, Vock, P, and Roos, JE. "Accuracy of low-dose computed tomography (CT) for detecting and characterizing the most common CT-patterns of pulmonary disease." European Journal of Radiology (2012). Full Text
  - Mann, SD, Perez, KL, McCracken, EKE, Shah, JP, Choudhury, KR, Wong, TZ, and Tornai, MP. "Quantification of Tc-99m sestamibi distribution in normal breast tissue using dedicated breast SPECT-CT." Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 7361 LNCS (2012): 402-409. Full Text
  - Michel, AM, Choudhury, KR, Firth, AE, Ingolia, NT, Atkins, JF, and Baranov, PV. "Observation of dually decoded regions of the human genome using ribosome profiling data." Genome Research 22, no. 11 (2012): 2219-2229. Full Text
  - Haase, JK, Murphy, RA, Choudhury, KR, and Achtman, M. "Revival of Seeliger's historical 'Special Listeria Culture Collection'." Environ Microbiol 13, no. 12 (December 2011): 3163-3171. Full Text Link to Item
  - Roy Choudhury, K, Boyle, L, Burke, M, Lombard, W, Ryan, S, and McNamara, B. "Intra subject variation and correlation of motor potentials evoked by transcranial magnetic stimulation." Ir J Med Sci 180, no. 4 (December 2011): 873-880. Full Text Link to Item
  - Christe, A, Torrente, JC, Lin, M, Yen, A, Hallett, R, Roychoudhury, K, Schmitzberger, F, Vock, P, and Roos, J. "CT screening and follow-up of lung nodules: effects of tube current-time setting and nodule size and density on detectability and of tube current-time setting on apparent size." AJR Am J Roentgenol 197, no. 3 (September 2011): 623-630. Full Text Link to Item
  - Hempel, A, Borchert, N, Walsh, H, Roy Choudhury, K, Kerry, JP, and Papkovsky, DB. "Analysis of total aerobic viable counts in raw fish by high-throughput optical oxygen respirometry." J Food Prot 74, no. 5 (May 2011): 776-782. Full Text Link to Item
  - Ghosh, J, Lal, CS, Pandey, K, Das, VNR, Das, P, Roychoudhury, K, and Roy, S. "Human visceral leishmaniasis: decrease in serum cholesterol as a function of splenic parasite load." Ann Trop Med Parasitol 105, no. 3 (April 2011): 267-271. Full Text Link to Item
  - Roy Choudhury, K, Kasman, I, and Plowman, GD. "Analysis of multi-arm tumor growth trials in xenograft animals using phase change adaptive piecewise quadratic models." Stat Med 29, no. 23 (October 15, 2010): 2399-2409. Full Text Link to Item
  - Choudhury, KR, Deacon, P, Barrett, R, and McDermott, K. "Hypothesis testing for neural cell growth experiments using a hybrid branching process model." Biostatistics 11, no. 4 (October 2010): 631-643. Full Text Link to Item
  - Choudhury, KR, Paik, DS, Yi, CA, Napel, S, Roos, J, and Rubin, GD. "Assessing operating characteristics of CAD algorithms in the absence of a gold standard." Med Phys 37, no. 4 (April 2010): 1788-1795. Full Text Link to Item
  - Roos, JE, Paik, D, Olsen, D, Liu, EG, Chow, LC, Leung, AN, Mindelzun, R, Choudhury, KR, Naidich, DP, Napel, S, and Rubin, GD. "Computer-aided detection (CAD) of lung nodules in CT scans: radiologist performance and reading time with incremental CAD assistance." Eur Radiol 20, no. 3 (March 2010): 549-557. Full Text Link to Item
  - Choudhury, KR, Yagle, KJ, Swanson, PE, Krohn, KA, and Rajendran, JG. "A robust automated measure of average antibody staining in immunohistochemistry images." J Histochem Cytochem 58, no. 2 (February 2010): 95-107. Full Text Link to Item
  - Choudhury, KR, O'Sullivan, F, Samanta, M, Caulliez, G, and Shrira, V. "Regularized reconstruction of wave height and slope fields from refracted images of water." Journal of the American Statistical Association 105, no. 489 (2010): 36-47. Full Text
  - Choudhury, KR, Zheng, L, and Mackrill, JJ. "Analysis of spatial distribution of marker expression in cells using boundary distance plots." Annals of Applied Statistics 4, no. 3 (2010): 1365-1382. Full Text
  - Crowe, O, Coombes, RH, Lysaght, L, O'Brien, C, Choudhury, KR, Walsh, AJ, Wilson, JH, and O'Halloran, J. "Population trends of widespread breeding birds in the Republic of Ireland 1998-2008." Bird Study 57, no. 3 (2010): 267-280. Full Text
  - Choudhury, KR. "Analysis of the variability of a two-dimensional finite strain estimate." Mathematical Geosciences 41, no. 5 (2009): 535-553. Full Text
  - Choudhury, KR, and Tabirca, S. "A modular CDF approach for the approximation of percentiles." Communications in Statistics: Simulation and Computation 37, no. 10 (2008): 1948-1965. Full Text
  - Holland, F, and Choudhury, KR. "Likelihood ratio tests for equality of shape under varying degrees of orientation invariance." Journal of Multivariate Analysis 99, no. 8 (2008): 1772-1792. Full Text
  - O'Sullivan, F, Huang, J, Choudhury, KR, Caulliez, G, and Shrira, V. "Regularized reconstruction of water surfaces from noisy gradient information via plane-wave superposition." Inverse Problems 24, no. 3 (2008). Full Text
  - Crotty, S, and Roy Choudhury, K. "Morphometric analysis for early detection of changes in cellular structure in a toxicological experiment." Stat Med 26, no. 29 (December 20, 2007): 5253-5266. Full Text Link to Item
  - Arya, A, Roychoudhury, K, and Bredin, CP. "Farmer's lung is now in decline." Ir Med J 99, no. 7 (July 2006): 203-205. Link to Item
  - Choudhury, KR, Meere, PA, and Mulchrone, KF. "Automated grain boundary detection by CASRG." Journal of Structural Geology 28, no. 3 (2006): 363-375. Full Text
  - Choudhury, KR, and Mulchrone, K. "A comparative error analysis of manual versus automated methods of data acquisition for algebraic strain estimation." Tectonophysics 421, no. 3-4 (2006): 209-230. Full Text
  - O'Sullivan, F, and Choudhury, KR. "A statistical measure of regularity for the study of wind-generated wave field images." Journal of the American Statistical Association 101, no. 475 (2006): 1119-1131. Full Text
  - Mulchrone, KF, Meere, PA, and Choudhury, KR. "SAPE: A program for semi-automatic parameter extraction for strain analysis." Journal of Structural Geology 27, no. 11 (2005): 2084-2098. Full Text
  - Mulchrone, KF, and Choudhury, KR. "Fitting an ellipse to an arbitrary shape: Implications for strain analysis." Journal of Structural Geology 26, no. 1 (2004): 143-153. Full Text
  - Eary, JF, O'Sullivan, F, Powitan, Y, Chandhury, KR, Vernon, C, Bruckner, JD, and Conrad, EU. "Sarcoma tumor FDG uptake measured by PET and patient outcome: a retrospective analysis." Eur J Nucl Med Mol Imaging 29, no. 9 (September 2002): 1149-1154. Full Text Link to Item
  - O'Sullivan, F, and Choudhury, KR. "An analysis of the role of positivity and mixture model constraints in poisson deconvolution problems." Journal of Computational and Graphical Statistics 10, no. 4 (2001): 673-696.
  - Fanning, L, Kenny-Walsh, E, Levis, J, Choudhury, KR, Cannon, B, Sheehan, M, Whelton, M, and Shanahan, F. "Natural fluctuations of hepatitis C viral load in a homogeneous patient population: a prospective study." Hepatology 31, no. 1 (January 2000): 225-229. Full Text Link to Item
  - Choudhury, KR, and O'Sullivan, F. "Constrained least squares regularization in PET." IEEE Nuclear Science Symposium & Medical Imaging Conference 3 (1996): 1757-1761.
  - Ghose, M, Bhattacharya, K, Ghosh, SS, Roychoudhury, K, and Datey, A. "Effect of foliar arrangement on the leaf epidermal structures in Areca palm (Areca catechu Linn.)." Acta Botanica Neerlandica 45, no. 3 (1996): 303-308.
  - Choudhury, KR, and O'Sullivan, F. "Statistical examination of FBP and ML for estimating mixture models from dynamic PET data." IEEE Nuclear Science Symposium & Medical Imaging Conference 2 (1995): 1237-1241.
Teaching & Mentoring
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- BIOSTAT 718: Analysis of Correlated and Longitudinal Data 2017

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