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Konstantinos Economopoulos

House Staff
Surgery

Selected Publications


Knee Injuries and Associated Risk Factors in National Basketball Association Athletes.

Journal Article Arthroscopy, sports medicine, and rehabilitation · October 2022 PurposeTo determine structural knee injury rates and to identify risk factors and the number of games missed associated with these injuries in National Basketball Association (NBA) players from the 2015 to 2020 seasons.MethodsPublicly ava ... Full text Cite

A Portable Negative Pressure Isolation System as a Solution to Minimize Exposure of Health Care Providers to Infectious Pathogens.

Journal Article Am Surg · August 2022 The COVID-19 pandemic has resulted in the exposure of many surgeons and healthcare providers (HCPs) to disease given high patient loads and limited availability of negative pressure rooms. For these reasons we pursued the development of a portable patient ... Full text Link to item Cite

Orthotopic Transplantation of Human Bioartificial Lung Grafts in a Porcine Model: A Feasibility Study.

Journal Article Seminars in thoracic and cardiovascular surgery · June 2022 Lung transplantation is the only treatment for end-stage lung disease; however, donor organ shortage and intense immunosuppression limit its broad clinical impact. Bioengineering of lungs with patient-derived cells could overcome these problems. We created ... Full text Cite

Clinical Examination of the Hip.

Journal Article The New England journal of medicine · June 2022 Full text Cite

Prevalence of Cannabinoid (CBD) Use in Orthopaedic Sports Medicine Patients.

Journal Article Orthopaedic journal of sports medicine · April 2022 BackgroundAlthough there is some evidence that cannabinoid (CBD) products may provide a therapeutic effect for musculoskeletal pain, little is known about the usage patterns or their prevalence of use in orthopaedic sports medicine patients.Pu ... Full text Cite

Liver Transplantation for Pediatric Hepatocellular Carcinoma: A Systematic Review.

Journal Article Cancers · March 2022 Liver transplantation (LT) is the only potentially curative option for children with unresectable hepatocellular carcinoma (HCC). We performed a systematic review of the MEDLINE, Scopus, Cochrane Library, and Web of Science databases (end-of-search date: 3 ... Full text Cite

Influence of peritoneal dialysis catheter type on complications and long-term outcomes: an updated systematic review and meta-analysis.

Journal Article J Nephrol · December 2021 BACKGROUND: There is currently no consensus regarding the optimal type of peritoneal dialysis catheter (PDC). We compared the outcomes of PDCs according to the number of cuffs, intercuff and intraperitoneal segment shape, and presence of a weighted tip. ME ... Full text Link to item Cite

Surgical versus percutaneous catheter placement for peritoneal dialysis: an updated systematic review and meta-analysis.

Journal Article J Nephrol · October 2021 BACKGROUND: No consensus currently exists regarding the optimal approach for peritoneal dialysis catheter placement. We aimed to compare the outcomes of percutaneous and surgical peritoneal dialysis catheter placement. METHODS: A systematic review of the l ... Full text Link to item Cite

Liver Transplantation for Intrahepatic Cholangiocarcinoma: A Meta-analysis and Meta-regression of Survival Rates.

Journal Article Transplantation · October 2021 BackgroundIntrahepatic cholangiocarcinoma (iCCA) is a contraindication to liver transplantation in most centers worldwide. Therefore, only a few such cases have been performed in each individual center, and the need for a systematic review and met ... Full text Cite

The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review.

Journal Article Obes Surg · April 2021 Single-anastomosis duodenoileal bypass with sleeve gastrectomy/one anastomosis duodenal switch (SADI-S/OADS) was developed as a bariatric operation with reduced overall morbidity and lasting weight loss results. We performed a systematic review of the lite ... Full text Open Access Link to item Cite

Presentation and surgical management of xanthogranulomatous cholecystitis.

Journal Article Hepatobiliary & pancreatic diseases international : HBPD INT · April 2021 BackgroundXanthogranulomatous cholecystitis (XGC) is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and most of the times requires surgical management. In addition, distinguishing XGC from gallbl ... Full text Cite

Laparoscopic versus robotic major hepatectomy: a systematic review and meta-analysis.

Journal Article Surgical endoscopy · February 2021 BackgroundThe implementation of the laparoscopic and robotic approaches for major hepatectomy (LMH and RMH) was slower than that for minor hepatectomy, but has significantly increased over the past years. The role or advantages of RMH remains cont ... Full text Cite

Carcinomas of the hypopharynx and cervical esophagus: A systematic review and quality of evidence assessment.

Journal Article Journal of B.U.ON. : official journal of the Balkan Union of Oncology · January 2021 PurposeHypopharyngeal cervical esophageal carcinoma (HPCEC) is a group of highly malignant entities usually presenting at an advanced stage. Our purpose was to systematically review and synthesize all available data on the management and outcomes ... Cite

Comparison of liquid-based to tissue-based biopsy analysis by targeted next generation sequencing in advanced non-small cell lung cancer: a comprehensive systematic review.

Journal Article Journal of cancer research and clinical oncology · August 2020 PurposeTo explore whether targeted next generation sequencing (NGS) of liquid biopsy in advanced non-small cell lung cancer (NSCLC) could potentially overcome the innate problems that arise with standard tissue biopsy, like intratumoral heterogene ... Full text Cite

Minimally Invasive Surgery vs Device Closure for Atrial Septal Defects: A Systematic Review and Meta-analysis.

Journal Article Pediatric cardiology · June 2020 Device closure is the first-line treatment for most atrial septal defects (ASDs). Minimally invasive cardiac surgery (MICS) has been found safe and effective for ASD closure with comparable mortality/morbidity and superior cosmetic results compared to conv ... Full text Cite

Acute esophageal necrosis: A systematic review and pooled analysis.

Journal Article World journal of gastrointestinal surgery · March 2020 BackgroundAcute esophageal necrosis (AEN) is a rare entity with multifactorial etiology, usually presenting with signs of upper gastrointestinal bleeding.AimTo systematically review all available data on demographics, clinical features, o ... Full text Cite

Association between endometriosis and gynecological cancers: a critical review of the literature.

Journal Article Archives of gynecology and obstetrics · February 2020 BackgroundEndometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcinomas such as clear cell and ... Full text Cite

Knee Injuries and Associated Risk Factors in National Basketball Association Athletes.

Journal Article Arthroscopy, sports medicine, and rehabilitation · October 2022 PurposeTo determine structural knee injury rates and to identify risk factors and the number of games missed associated with these injuries in National Basketball Association (NBA) players from the 2015 to 2020 seasons.MethodsPublicly ava ... Full text Cite

A Portable Negative Pressure Isolation System as a Solution to Minimize Exposure of Health Care Providers to Infectious Pathogens.

Journal Article Am Surg · August 2022 The COVID-19 pandemic has resulted in the exposure of many surgeons and healthcare providers (HCPs) to disease given high patient loads and limited availability of negative pressure rooms. For these reasons we pursued the development of a portable patient ... Full text Link to item Cite

Orthotopic Transplantation of Human Bioartificial Lung Grafts in a Porcine Model: A Feasibility Study.

Journal Article Seminars in thoracic and cardiovascular surgery · June 2022 Lung transplantation is the only treatment for end-stage lung disease; however, donor organ shortage and intense immunosuppression limit its broad clinical impact. Bioengineering of lungs with patient-derived cells could overcome these problems. We created ... Full text Cite

Clinical Examination of the Hip.

Journal Article The New England journal of medicine · June 2022 Full text Cite

Prevalence of Cannabinoid (CBD) Use in Orthopaedic Sports Medicine Patients.

Journal Article Orthopaedic journal of sports medicine · April 2022 BackgroundAlthough there is some evidence that cannabinoid (CBD) products may provide a therapeutic effect for musculoskeletal pain, little is known about the usage patterns or their prevalence of use in orthopaedic sports medicine patients.Pu ... Full text Cite

Liver Transplantation for Pediatric Hepatocellular Carcinoma: A Systematic Review.

Journal Article Cancers · March 2022 Liver transplantation (LT) is the only potentially curative option for children with unresectable hepatocellular carcinoma (HCC). We performed a systematic review of the MEDLINE, Scopus, Cochrane Library, and Web of Science databases (end-of-search date: 3 ... Full text Cite

Influence of peritoneal dialysis catheter type on complications and long-term outcomes: an updated systematic review and meta-analysis.

Journal Article J Nephrol · December 2021 BACKGROUND: There is currently no consensus regarding the optimal type of peritoneal dialysis catheter (PDC). We compared the outcomes of PDCs according to the number of cuffs, intercuff and intraperitoneal segment shape, and presence of a weighted tip. ME ... Full text Link to item Cite

Surgical versus percutaneous catheter placement for peritoneal dialysis: an updated systematic review and meta-analysis.

Journal Article J Nephrol · October 2021 BACKGROUND: No consensus currently exists regarding the optimal approach for peritoneal dialysis catheter placement. We aimed to compare the outcomes of percutaneous and surgical peritoneal dialysis catheter placement. METHODS: A systematic review of the l ... Full text Link to item Cite

Liver Transplantation for Intrahepatic Cholangiocarcinoma: A Meta-analysis and Meta-regression of Survival Rates.

Journal Article Transplantation · October 2021 BackgroundIntrahepatic cholangiocarcinoma (iCCA) is a contraindication to liver transplantation in most centers worldwide. Therefore, only a few such cases have been performed in each individual center, and the need for a systematic review and met ... Full text Cite

The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review.

Journal Article Obes Surg · April 2021 Single-anastomosis duodenoileal bypass with sleeve gastrectomy/one anastomosis duodenal switch (SADI-S/OADS) was developed as a bariatric operation with reduced overall morbidity and lasting weight loss results. We performed a systematic review of the lite ... Full text Open Access Link to item Cite

Presentation and surgical management of xanthogranulomatous cholecystitis.

Journal Article Hepatobiliary & pancreatic diseases international : HBPD INT · April 2021 BackgroundXanthogranulomatous cholecystitis (XGC) is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and most of the times requires surgical management. In addition, distinguishing XGC from gallbl ... Full text Cite

Laparoscopic versus robotic major hepatectomy: a systematic review and meta-analysis.

Journal Article Surgical endoscopy · February 2021 BackgroundThe implementation of the laparoscopic and robotic approaches for major hepatectomy (LMH and RMH) was slower than that for minor hepatectomy, but has significantly increased over the past years. The role or advantages of RMH remains cont ... Full text Cite

Carcinomas of the hypopharynx and cervical esophagus: A systematic review and quality of evidence assessment.

Journal Article Journal of B.U.ON. : official journal of the Balkan Union of Oncology · January 2021 PurposeHypopharyngeal cervical esophageal carcinoma (HPCEC) is a group of highly malignant entities usually presenting at an advanced stage. Our purpose was to systematically review and synthesize all available data on the management and outcomes ... Cite

Comparison of liquid-based to tissue-based biopsy analysis by targeted next generation sequencing in advanced non-small cell lung cancer: a comprehensive systematic review.

Journal Article Journal of cancer research and clinical oncology · August 2020 PurposeTo explore whether targeted next generation sequencing (NGS) of liquid biopsy in advanced non-small cell lung cancer (NSCLC) could potentially overcome the innate problems that arise with standard tissue biopsy, like intratumoral heterogene ... Full text Cite

Minimally Invasive Surgery vs Device Closure for Atrial Septal Defects: A Systematic Review and Meta-analysis.

Journal Article Pediatric cardiology · June 2020 Device closure is the first-line treatment for most atrial septal defects (ASDs). Minimally invasive cardiac surgery (MICS) has been found safe and effective for ASD closure with comparable mortality/morbidity and superior cosmetic results compared to conv ... Full text Cite

Acute esophageal necrosis: A systematic review and pooled analysis.

Journal Article World journal of gastrointestinal surgery · March 2020 BackgroundAcute esophageal necrosis (AEN) is a rare entity with multifactorial etiology, usually presenting with signs of upper gastrointestinal bleeding.AimTo systematically review all available data on demographics, clinical features, o ... Full text Cite

Association between endometriosis and gynecological cancers: a critical review of the literature.

Journal Article Archives of gynecology and obstetrics · February 2020 BackgroundEndometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcinomas such as clear cell and ... Full text Cite

Concomitant cholecystectomy during bariatric surgery: The jury is still out.

Journal Article American journal of surgery · August 2019 BackgroundWe sought to compare clinical outcomes of concomitant cholecystectomy during four different types of bariatric surgery vs. bariatric surgery alone.Data sourcesA systematic literature search of PubMed and Cochrane databases was c ... Full text Cite

Fluoroquinolone-based versus β-lactam-based regimens for complicated intra-abdominal infections: a meta-analysis of randomised controlled trials.

Journal Article International journal of antimicrobial agents · June 2019 Complicated intra-abdominal infections (cIAIs) are common and confer significant morbidity, mortality and costs. In this era of evolving antimicrobial resistance, selection of appropriate empirical antimicrobials is paramount. This systematic review and me ... Full text Cite

Suitability study of current endovascular aortic repair devices based on real-life anatomic data.

Journal Article Expert review of medical devices · February 2019 BackgroundThere are a number of stent-grafts in the market, designed to handle difficult anatomies during endovascular aortic repair. The aim of this study is to determine which stent-graft is the most appropriate to accommodate the majority of in ... Full text Cite

Metabolic glycan labeling and chemoselective functionalization of native biomaterials.

Journal Article Biomaterials · November 2018 Decellularized native extracellular matrix (ECM) biomaterials are widely used in tissue engineering and have reached clinical application as biomesh implants. To enhance their regenerative properties and postimplantation performance, ECM biomaterials could ... Full text Cite

Predictors of surveillance mammography outcomes in women with a personal history of breast cancer.

Journal Article Breast cancer research and treatment · August 2018 PurposeTo identify predictors of poor mammography surveillance outcomes based on clinico-pathologic features.MethodsThis study was HIPAA compliant and IRB approved. We performed an electronic medical record review for a cohort of women wi ... Full text Cite

Proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: A systematic review and meta-analysis.

Journal Article Cardiovascular revascularization medicine : including molecular interventions · July 2018 ObjectiveProximal embolic protection devices (P-EPD) and distal filters (DF) are used to prevent distal cerebral embolizations during carotid artery stenting (CAS). We compared their comparative effectiveness in regards to prevention of intraproce ... Full text Cite

Current evidence on the role of smoking in plastic surgery elective procedures: A systematic review and meta-analysis.

Journal Article Journal of plastic, reconstructive & aesthetic surgery : JPRAS · May 2018 BackgroundSmoking is considered to be a significant risk factor for the development of postoperative complications after various surgical procedures, mainly by limiting oxygen delivery to tissues. Evidence on the collective impact of smoking in ae ... Full text Cite

Mortality after endovascular treatment of infrarenal abdominal aortic aneurysms - the newer the better?

Journal Article VASA. Zeitschrift fur Gefasskrankheiten · April 2018 Although endovascular repair of infrarenal abdominal aortic aneurysms (EVAR) presents a delicate alternative treatment for abdominal aortic aneurysms (AAA) with lower perioperative mortality, its long-term efficacy remains a matter of concern. The purpose ... Full text Cite

Pediatric Cardiac Trauma in the United States: A Systematic Review.

Journal Article World journal for pediatric & congenital heart surgery · March 2018 Literature discussing cardiac injuries in children is limited. Systematic search of PubMed identified 21 studies enrolling 1,062 pediatric patients who experienced cardiac trauma in the United States during the period 1961 to 2012. The predominant type of ... Full text Cite

Antibiotics exposure and risk of inflammatory bowel disease: a systematic review.

Journal Article Scandinavian journal of gastroenterology · January 2018 AimThe aim of this study was to critically assess all available evidence suggesting an association between antibiotic exposure and new onset of inflammatory bowel disease (IBD).Materials and methodsThis systematic review was conducted acc ... Full text Cite

Stem Cell Therapy for Congenital Heart Disease: A Systematic Review.

Journal Article Circulation · December 2017 Featured Publication BackgroundCongenital heart disease (CHD) constitutes the most prevalent and heterogeneous group of congenital anomalies. Although surgery remains the gold standard treatment modality, stem cell therapy has been gaining ground as a complimentary or ... Full text Cite

Blood Versus Crystalloid Cardioplegia in Pediatric Cardiac Surgery: A Systematic Review and Meta-analysis.

Journal Article Pediatric cardiology · December 2017 The benefit of blood cardioplegia (BCP) compared to crystalloid cardioplegia (CCP) is still debatable. Our aim was to systematically review and synthesize all available evidence on the use of BCP and CCP to assess if any modality provides superior outcomes ... Full text Cite

Adrenal ganglioneuroma: What you need to know.

Journal Article World journal of clinical cases · October 2017 Adrenal ganglioneuromas (GNs) constitute rare, differentiated tumors which originate from neural crest cells. GNs are usually hormonally silent and tend to be discovered incidentally on imaging tests. Adrenalectomy is the gold standard for the treatment of ... Full text Cite

Robotic Resection of Small Pulmonary Nodules after Image-Guided Marker Placement

Conference Journal of the American College of Surgeons · October 2017 Full text Cite

Emerging treatments for ulcerative colitis: a systematic review.

Journal Article Scandinavian journal of gastroenterology · September 2017 ObjectivesVarious investigational medicinal products have been developed for ulcerative colitis (UC). Our aim was to systematically evaluate novel pharmacological therapeutic agents for the treatment of UC.Material and methodsPreferred Re ... Full text Cite

Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice.

Journal Article Digestive diseases and sciences · August 2017 Background and aimsBacterially derived factors from the gut play a major role in the activation of inflammatory pathways in the liver and in the pathogenesis of alcoholic liver disease. The intestinal brush-border enzyme intestinal alkaline phosph ... Full text Cite

Mullerian dysgenesis: a critical review of the literature.

Journal Article Archives of gynecology and obstetrics · June 2017 PurposeTo present an update of the genetic, clinical, diagnostic, and therapeutic aspects of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.MethodsStudies were considered eligible if they have evaluated patients with MRKH syndrome. Eligib ... Full text Cite

Operation versus antibiotics--The "appendicitis conundrum" continues: A meta-analysis.

Journal Article The journal of trauma and acute care surgery · June 2017 BackgroundAcute appendicitis continues to constitute a diagnostic and therapeutic challenge. The aim of this study was to synthesize evidence from randomized controlled trials (RCTs) comparing nonoperative versus surgical management of uncomplicat ... Full text Cite

Engineering Bioartificial Lungs for Transplantation

Journal Article Current Stem Cell Reports · June 1, 2017 Purpose of Review: The purposes of this study were to review current progress being made in engineering bioartificial lungs for transplantation and identify tangible benefits to the implementation of this research into development of 4D lung models for dis ... Full text Cite

Measurement and Variation in Estimation of Quality of Life Effects of Patients Undergoing Treatment for Papillary Thyroid Carcinoma.

Journal Article Thyroid : official journal of the American Thyroid Association · February 2017 BackgroundThyroid cancer incidence is increasing. The effect of diagnosis and treatment on health-related quality of life (HRQoL) is an essential variable in the absence of a change in life span for the majority of patients. HRQoL instruments, wit ... Full text Cite

Laparoscopic versus robotic adrenalectomy: A comprehensive meta-analysis.

Journal Article International journal of surgery (London, England) · February 2017 Featured Publication BackgroundThe benefit of robotic adrenalectomy (RA) compared to laparoscopic adrenalectomy (LA) is still debatable. The purpose of this paper was to systematically review and synthesize all available evidence comparing RA to LA so as to evaluate w ... Full text Cite

Intestinal alkaline phosphatase decreases intraperitoneal adhesion formation.

Journal Article The Journal of surgical research · February 2017 BackgroundDamage to the peritoneum initiates an inflammatory response leading to the formation of adhesions, which subsequently cause significant morbidity in some patients. Intestinal alkaline phosphatase (IAP) is a gut enzyme capable of detoxify ... Full text Cite

Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.

Journal Article Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · January 2017 Diet soda consumption has not been associated with tangible weight loss. Aspartame (ASP) commonly substitutes sugar and one of its breakdown products is phenylalanine (PHE), a known inhibitor of intestinal alkaline phosphatase (IAP), a gut enzyme shown to ... Full text Cite

Refugee crisis in Greece: not a one-country job.

Journal Article International journal of public health · January 2017 Featured Publication Full text Cite

Violent death and trauma in Norse mythology: a systematic reading of the Prose Edda

Journal Article European Surgery - Acta Chirurgica Austriaca · October 1, 2016 Background: This paper attempts to assess surgical knowledge presented in Norse mythology. The Prose Edda constitutes the most comprehensive source of Norse mythology. Literature and myth offer unique educational insights into life practices of previous er ... Full text Cite

Access to health for refugees in Greece: lessons in inequalities.

Journal Article International journal for equity in health · August 2016 Eastern Greek islands have been direct passageways of (mainly Syrian) refugees to the European continent over the past year. However, basic medical care has been insufficient. Despite calls for reform, the Greek healthcare system has for many years been co ... Full text Cite

History of the infantile hepatic hemangioma: From imaging to generating a differential diagnosis.

Journal Article World journal of clinical pediatrics · August 2016 We aim to provide an up-to-date summary of infantile hepatic hemangioma (IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver. Eligible peer-reviewed articles on hepatic infantile hemangiomas, p ... Full text Cite

From the Classroom to Facebook: A Fresh Approach for Youth Tobacco Prevention.

Journal Article American journal of health promotion : AJHP · May 2016 PurposeThe explosive rise in Internet use calls for effective ways to utilize new forms of social media to enhance school smoking prevention programs. We attempted to design and test an educational intervention for youth tobacco prevention.Des ... Full text Cite

Laparoendoscopic single-site surgery (LESS) for major urological procedures in the pediatric population: A systematic review.

Journal Article International journal of surgery (London, England) · May 2016 BackgroundImprovements in laparoscopic surgery have led to the introduction of laparoendoscopic single-site surgery (LESS) as an alternative to conventional laparoscopy conferring a number of possible advantages. In this review, we aim to elucidat ... Full text Cite

Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase.

Journal Article Diabetes, obesity & metabolism · May 2016 AimsTo examine whether co-administration of intestinal alkaline phosphatase (IAP) with antibiotics early in life may have a preventive role against metabolic syndrome (MetS) in mice.MethodsA total of 50 mice were allocated to four treatme ... Full text Cite

Laparoscopic cholecystectomy during pregnancy: A systematic review of 590 patients.

Journal Article International journal of surgery (London, England) · March 2016 BackgroundThe incidence of symptomatic biliary disease during pregnancy ranges from 0.05 to 8%. Cholecystectomy is one of the common operations performed during pregnancy and laparoscopic approach has gained popularity as an attractive alternative ... Full text Cite

PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer.

Journal Article Cell metabolism · February 2016 Featured Publication Cachexia is a wasting syndrome associated with elevated basal energy expenditure and loss of adipose and muscle tissues. It accompanies many chronic diseases including renal failure and cancer and is an important risk factor for mortality. Our recent work ... Full text Cite

Detection of Circulating BRAF(V600E) in Patients with Papillary Thyroid Carcinoma.

Journal Article The Journal of molecular diagnostics : JMD · January 2016 BRAF(V600E) is a common mutation in papillary thyroid carcinoma (PTC) correlated with aggressive features. Our objective was to assess the feasibility and accuracy of a novel RNA-based blood assay to identify individuals with a high-risk tumor mutation in ... Full text Cite

Should specific patient clinical characteristics discourage adrenal surgeons from performing laparoscopic transperitoneal adrenalectomy?

Conference Surgery · January 2016 BackgroundAlthough laparoscopic transperitoneal adrenalectomy (LTA) has become a standard operative approach to patients with benign adrenal masses, some authors have suggested that LTA should be avoided in obese patients, patients who have had pr ... Full text Cite

Firearm Injury in the United States: An Overview of an Evolving Public Health Problem.

Journal Article Journal of the American College of Surgeons · December 2015 Full text Cite

Laparoscopic surgery for gastric cancer: a systematic review

Journal Article European Surgery - Acta Chirurgica Austriaca · December 1, 2015 Background: The objective of this paper is to systematically review current literature on laparoscopic surgery for gastric cancer in terms of current indications and feasibility as well as short-term and long-term postoperative outcomes. Methods: A systema ... Full text Cite

Robotic vs. Laparoscopic Roux-En-Y Gastric Bypass: a Systematic Review and Meta-Analysis.

Journal Article Obesity surgery · November 2015 We aim to summarize the available literature on patients treated with robotic RYGB and compare the clinical outcomes of patients treated with robotic RYGB with those treated with the standard laparoscopic RYGB. A systematic literature search of PubMed and ... Full text Cite

Cost-Effectiveness of Screening for Primary Aldosteronism and Subtype Diagnosis in the Resistant Hypertensive Patients.

Journal Article Circulation. Cardiovascular quality and outcomes · November 2015 BackgroundPrimary aldosteronism (PA) is a common and underdiagnosed disease with significant morbidity potentially cured by surgery. We aim to assess if the long-term cardiovascular benefits of identifying and treating surgically correctable PA ou ... Full text Cite

Reply to: Continuous versus cyclic oral contraceptives for endometriosis: any conclusive evidence?

Journal Article Archives of gynecology and obstetrics · September 2015 Full text Cite

Single Incision Laparoscopic Sleeve Gastrectomy: a Review.

Journal Article Obesity surgery · August 2015 We aim to summarize the existing evidence on the use of single incision sleeve gastrectomy (SILSG) for morbid obesity. A thorough literature search for studies reporting outcomes of SILSG was performed. Data on patient demographics, operative details, and ... Full text Cite

Transumbilical Roux-en-Y gastric bypass in morbidly obese patients: A systematic review.

Journal Article International journal of surgery (London, England) · August 2015 BackgroundTransumbilical single-incision Roux-en-Y gastric bypass constitutes a delicate technique of the conventional laparoscopic approach, which is the gold standard for the treatment of obesity.MethodsIn order to investigate its effic ... Full text Cite

Talking the talk: The keys to effective workplace communication.

Journal Article Bulletin of the American College of Surgeons · August 2015 Cite

From the Classroom to Facebook: A Fresh Approach for Youth Tobacco Prevention

Journal Article American Journal of Health Promotion · July 9, 2015 Full text Cite

Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review.

Journal Article Archives of gynecology and obstetrics · July 2015 PurposeRecurrence of endometriosis after conservative surgery has been observed in 40-50 % of patients within the first 5 years. A variety of regimens such as combined oral contraceptives, GnRH agonists, danazol, and progestins have been used post ... Full text Cite

Adjunct endovascular interventions in carotid body tumors.

Journal Article Journal of vascular surgery · April 2015 ObjectiveMost patients presenting with carotid body tumors (CBTs) seek medical attention when tumors have grown to exceed Shamblin I stage, rendering surgery a challenging undertaking and the associated morbidity a continuing threat to the clinica ... Full text Cite

A national survey of educational resources utilized by the Resident and Associate Society of the American College of Surgeons membership.

Journal Article American journal of surgery · January 2015 BackgroundContemporary surgical education includes online resources, mobile platform applications, and simulation training. The aim of this study was to characterize educational tools used by surgical residents.MethodsAn anonymous web-bas ... Full text Cite

A novel approach to maintain gut mucosal integrity using an oral enzyme supplement.

Conference Annals of surgery · October 2014 ObjectiveTo determine the role of intestinal alkaline phosphatase (IAP) in enteral starvation-induced gut barrier dysfunction and to study its therapeutic effect as a supplement to prevent gut-derived sepsis.BackgroundCritically ill patie ... Full text Cite

Coaching and mentoring modern surgeons.

Journal Article Bulletin of the American College of Surgeons · August 2014 Cite

Treatment and Prognosis for Patients With Intrahepatic Cholangiocarcinoma: Systematic Review and Meta-analysis.

Journal Article JAMA surgery · June 2014 Featured Publication ImportanceData on outcomes following surgical management of intrahepatic cholangiocarcinoma (ICC) are limited. The incidence of ICC is increasing and it has a poor prognosis. No consensus has been reached regarding the optimal treatment modalities ... Full text Cite

Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile.

Journal Article Thyroid : official journal of the American Thyroid Association · June 2014 Featured Publication BackgroundPapillary thyroid carcinoma (PTC) is increasing in incidence while mortality is unchanged. Identifying patients with higher risk of recurrence and death is essential. Case series identify the hobnail variant of PTC (HVPTC), which is char ... Full text Cite

Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates.

Journal Article American journal of physiology. Gastrointestinal and liver physiology · May 2014 Featured Publication The intestinal microbiota plays a pivotal role in maintaining human health and well-being. Previously, we have shown that mice deficient in the brush-border enzyme intestinal alkaline phosphatase (IAP) suffer from dysbiosis and that oral IAP supplementatio ... Full text Cite

Annual financial impact of well-differentiated thyroid cancer care in the United States.

Journal Article Cancer · May 2014 Featured Publication BackgroundWell-differentiated thyroid cancer (WDTC) is a prevalent disease, which is increasing in incidence faster than any other cancer. Substantial direct medical care costs are related to the diagnosis and treatment of newly diagnosed patients ... Full text Cite

The effect of intestinal alkaline phosphatase on abscess fluid-induced inflammation

Conference Journal of the American College of Surgeons · September 2013 Full text Cite

Intestinal alkaline phosphatase is an endogenous regulator of host microbiota

Conference Journal of the American College of Surgeons · September 2013 Full text Cite

An overview of laparoscopic techniques in abdominal aortic aneurysm repair.

Journal Article Journal of vascular surgery · August 2013 BackgroundSince 1993, various laparoscopic techniques have been developed to make laparoscopic treatment of abdominal aortic aneurysms (AAAs) a possible therapeutic alternative. We aim to review all published clinical studies on laparoscopic surge ... Full text Cite

Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · April 2013 Featured Publication Metabolic syndrome comprises a cluster of related disorders that includes obesity, glucose intolerance, insulin resistance, dyslipidemia, and fatty liver. Recently, gut-derived chronic endotoxemia has been identified as a primary mediator for triggering th ... Full text Cite

Scar perceptions after thyroid and parathyroid surgery: comparison of minimal and conventional approaches.

Journal Article Surgery · March 2013 BackgroundAn incision less than 3 cm in length in the neck is the main feature that discriminates the minimally invasive thyroidectomy and parathyroidectomy from traditional procedures. Smaller neck scars are assumed to yield better patient satisf ... Full text Cite

The fatal disease of Emperor Galerius.

Journal Article Journal of the American College of Surgeons · December 2012 Full text Cite

Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ovarian cancer risk: a meta-analysis.

Journal Article Molecular biology reports · November 2012 This meta-analysis aims to examine whether the genotype status of MspI, Ile462Val, and Thr461Asn polymorphisms in Cytochrome P450 1A1 (CYP1A1) is associated with ovarian cancer risk. Eligible case-control studies were identified through search in MEDLINE ( ... Full text Cite

Surgical leadership across generations.

Journal Article Bulletin of the American College of Surgeons · August 2012 Cite

Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and cervical cancer risk: a meta-analysis.

Journal Article Molecular biology reports · June 2012 This meta-analysis aims to examine whether the genotype status of MspI and Ile462Val polymorphisms in Cytochrome-P450 1A1 (CYP1A1) is associated with cervical cancer risk. Eligible case-control studies were identified through search in MEDLINE (end of sear ... Full text Cite

Psychometric evaluation of Patient Scar Assessment Questionnaire following thyroid and parathyroid surgery.

Journal Article Thyroid : official journal of the American Thyroid Association · February 2012 BackgroundThe Patient Scar Assessment Questionnaire (PSAQ) was constructed to evaluate the effect of any surgical therapy with a linear scar. This study aims to demonstrate reliability and validity of Appearance and Consciousness subscales of PSAQ ... Full text Cite

The plague of Thebes, a historical epidemic in Sophocles' Oedipus Rex.

Journal Article Emerging infectious diseases · January 2012 Sophocles, one of the most noted playwrights of the ancient world, wrote the tragedy Oedipus Rex in the first half of the decade 430-420 bc. A lethal plague is described in this drama. We adopted a critical approach to Oedipus Rex in analyzing the literary ... Full text Cite

Endoscopic thyroidectomy in the neck

Chapter · January 1, 2012 Although minimally invasive thyroidectomy started as a “closed” purely endoscopic thyroidectomy with incisions in the neck, today these techniques are not widely practiced. They are mentioned though for their historical interest and potential lessons for o ... Full text Cite

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.

Journal Article Molecular biology reports · November 2011 Cyclin D1 represents a key molecule in the regulation of cell cycle. CCND1 G870A (rs603965) polymorphism has drawn considerable attention as the A allele may generate a variant splice product with possible oncogenic actions. A meta-analysis examining the a ... Full text Cite

Impact of posterior retroperitoneoscopic adrenalectomy in a tertiary care center: a paradigm shift.

Journal Article Surgical endoscopy · November 2011 BackgroundPosterior retroperitoneoscopic adrenalectomy has substituted its anterior laparoscopic counterpart as the treatment of choice in the management of adrenal tumors at the authors' institution. The authors present their comparative results ... Full text Cite

Manual high-dose regional intraoperative thrombolysis of lower extremity emboli after open repair of a ruptured abdominal aortic aneurysm.

Journal Article Annals of vascular surgery · October 2011 We describe a case of high-dose regional intraoperative thrombolysis subsequent to mechanical thrombectomy for the treatment of postoperative distal extremity embolization of the right lower limb owing to open repair of a ruptured abdominal aortic aneurysm ... Full text Cite

Completion of the Patient Scar Assessment Scale via a telephone interview.

Journal Article Archives of otolaryngology--head & neck surgery · June 2011 Full text Cite

Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes.

Journal Article Stroke · March 2011 Featured Publication Background and purposeThe comparison between carotid endarterectomy and carotid artery stenting (CAS) remains a debated field, especially in the context of long-term outcomes.MethodsConcerning the short-term (30-day) analysis, the numbers ... Full text Cite

Cytochrome P450 1A1 gene polymorphisms and endometrial cancer risk: a meta-analysis.

Journal Article International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · February 2011 IntroductionThis meta-analysis aims to examine whether the genotype status of Msp1, Ile462Val, and Thr461Asn polymorphisms in cytochrome P450 1A1 (CYP1A1) is associated with endometrial cancer risk.MethodsEligible case-control studies wer ... Full text Cite

GSTM1 polymorphism, GSTT1 polymorphism, and cervical cancer risk: a meta-analysis.

Journal Article International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · December 2010 IntroductionA debate exists about whether glutathione S-transferase (GST) polymorphisms (GST mu-1 [GSTM1] null/present genotype and GST theta-1 [GSTT1] null/present genotype) confer additional risk for cervical cancer. This meta-analysis was aimed ... Full text Cite

Methodological remarks concerning the recent meta-analysis on p53 codon 72 polymorphism and colorectal cancer risk.

Journal Article European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · December 2010 Full text Cite

Commentary: Higher paraplegia/paraparesis and technical success rates of concurrent hybrid procedures in the treatment of thoracoabdominal aortic aneurysms.

Journal Article Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · October 2010 Full text Cite

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Journal Article Journal of Endovascular Therapy · October 1, 2010 Full text Cite

Fertility drugs and ovarian cancer risk: a critical review of the literature.

Conference Annals of the New York Academy of Sciences · September 2010 There is evidence that medications used for ovarian stimulation and in vitro fertilization may be associated with ovarian cancer. In this review, we attempt to describe this relationship according to the most recent epidemiologic data and to present the po ... Full text Cite

Early use of TIPS for cirrhosis and variceal bleeding.

Journal Article The New England journal of medicine · September 2010 Full text Cite

Four polymorphisms in cytochrome P450 1A1 (CYP1A1) gene and breast cancer risk: a meta-analysis.

Journal Article Breast cancer research and treatment · July 2010 Cytochrome P450s are enzymes which catalyze Phase-I metabolism reactions; cytochrome P450 1A1 (CYP1A1) is a member of the CYP1 family and participates in the metabolism of a vast number of xenobiotics, as well as endogenous substrates. Four single nucleoti ... Full text Cite

Glutathione S-transferase M1, T1, and P1 polymorphisms and ovarian cancer risk: a meta-analysis.

Journal Article International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · July 2010 Featured Publication IntroductionCytosolic glutathione S-transferase (GST) comprises multiple isoenzymes that catalyze reactions between glutathione and lipophilic compounds with electrophilic centers, resulting in the neutralization of toxic compounds, xenobiotics, a ... Full text Cite

Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis.

Journal Article Breast cancer research and treatment · July 2010 Cytochrome P450 1B1 (CYP1B1) is a P450 enzyme implicated in the metabolism of exogenous and endogenous substrates. The metabolism of polycyclic aromatic hydrocarbons and other procarcinogens through CYP1B1 may well lead to their activation. Apart from the ... Full text Cite

Carotid endarterectomy versus carotid angioplasty with or without stenting for treatment of carotid artery stenosis: an updated meta-analysis of randomized controlled trials.

Journal Article International angiology : a journal of the International Union of Angiology · June 2010 Carotid angioplasty with or without stent placement (CAS) has been proposed as an alternative to carotid endarterectomy (CEA) for the treatment of carotid artery stenosis. We performed a systematic review and meta-analysis of randomized controlled trials t ... Cite

GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis.

Journal Article European journal of cancer (Oxford, England : 1990) · June 2010 Featured Publication Glutathione S-transferases (GSTs) catalyse reactions between glutathione and lipophilic compounds with electrophilic centres, leading to neutralisation of toxic compounds, xenobiotics and products of oxidative stress. Controversy exists about whether GST p ... Full text Cite

XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis.

Journal Article Breast cancer research and treatment · June 2010 XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) is a member of the RecA/Rad51-related protein family that participates in homologous recombination, maintaining chromosome stability and participating in DNA repair. Attention h ... Full text Cite

GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis.

Journal Article Breast cancer research and treatment · May 2010 Cytosolic glutathione S-transferase comprises multiple isoenzymes; studies have principally examined mu-1 (GSTM1: null/present), theta-1 (GSTT1: null/present) and pi-1 (GSTP1 Ile105Val) gene polymorphisms concerning breast cancer risk. Regarding GSTT1 and ... Full text Cite

Internal versus external tocodynamometry in labor.

Journal Article The New England journal of medicine · May 2010 Full text Cite

Fenestrated and branched endografts for the treatment of thoracoabdominal aortic aneurysms: a systematic review.

Journal Article Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · April 2010 Featured Publication PurposeTo offer a critical review of the current literature on the use of fenestrated and branched stent-grafts in patients with thoracoabdominal aortic aneurysms (TAAA).MethodsA thorough search of the English-language literature publishe ... Full text Cite

Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis.

Journal Article Breast cancer research and treatment · February 2010 Caspase-8 (CASP8) is an initiator caspase implicated in the process of apoptosis in breast cancer cells. Attention has been drawn upon two polymorphisms: CASP8 D302H (rs1045485) and, more recently, CASP8 -652 6N del (rs3834129). The CASP8 -652 6N del polym ... Full text Cite

Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis.

Journal Article Breast cancer research and treatment · February 2010 MDM2 SNP309 is a single nucleotide T > G polymorphism present in intron 1 of the MDM2 gene. A variety of case-control studies have been published evaluating the association between MDM2 SNP309 and breast cancer risk. However, the published studies, as well ... Full text Cite

Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer.

Journal Article Best practice & research. Clinical obstetrics & gynaecology · February 2010 There is evidence that endometriosis as well as drugs used in the process of in vitro fertilisation appear to associate with increased risk for gynaecological cancer. In this review, we attempt to describe this relationship according to the most recent epi ... Full text Cite

Transradial access for carotid artery stenting: a single-center experience.

Journal Article International angiology : a journal of the International Union of Angiology · February 2010 AimThe aim of this study was to report our initial experience using the radial artery as access for carotid artery stenting (CAS) and review the existing literature.MethodsFrom January to June 2008, nine high-risk consecutive patients wer ... Cite

Association between p53 Arg72Pro polymorphism and colorectal cancer risk: a meta-analysis.

Journal Article Onkologie · January 2010 BackgroundThis meta-analysis on case-control studies aims to examine whether the p53 Arg72Pro polymorphism is associated with colorectal cancer risk, addressing also whether the effect of the polymorphism is modified by race.Patients and metho ... Full text Cite

Concurrent versus two-stage hybrid procedures in the treatment of thoracoabdominal aortic aneurysms.

Journal Article Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · December 2009 Full text Cite

Minilaparotomy abdominal aortic aneurysm repair in the era of minimally invasive vascular surgery: preliminary results.

Journal Article ANZ journal of surgery · November 2009 BackgroundThis study aimed to evaluate the early post-operative clinical impact of minimal incision aortic surgery (MIAS) for infrarenal abdominal aortic aneurysm (AAA) repair in comparison with the standard open repair.MethodsA case-cont ... Full text Cite

Guided remote endarterectomy for superficial femoral artery occlusions: a technical note.

Journal Article International angiology : a journal of the International Union of Angiology · October 2009 The aim of this paper was to describe a new modification of the remote endarterectomy for the treatment of long superficial femoral artery (SFA) occlusions and to present our preliminary results. Through a subinguinal incision and arteriotomy over the SFA ... Cite

Follicular development, acquisition of mature oocytes, and pregnancy after 2 weeks of leuprolide acetate administration during the midluteal phase.

Journal Article Fertility and sterility · September 2009 ObjectiveTo present a case of aberrant follicular development, acquisition of mature oocytes, and pregnancy after 2 weeks of leuprolide acetate administration during the midluteal phase.DesignCase report.SettingDepartment of Obst ... Full text Cite

Hybrid procedures in the treatment of thoracoabdominal aortic aneurysms: a systematic review.

Journal Article Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · August 2009 PurposeTo summarize the existing evidence on the use of hybrid open/endovascular repair in patients with thoracoabdominal aortic aneurysms (TAAA).MethodsA thorough search was performed of the English-language literature published between ... Full text Cite

Bizarre leiomyoma of the posterior vaginal fornix.

Journal Article International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · September 2008 Full text Cite

A hybrid approach using a composite endovascular and open graft procedure for a symptomatic common femoral aneurysm extending well above the inguinal ligament.

Journal Article Journal of vascular surgery · August 2008 We report the use of a unique hybrid technique to treat a patient with a painful aneurysm extending both above and below the inguinal ligament. The patient was at high surgical risk, and endovascular treatment was not possible due to the absence of an appr ... Full text Cite

Meta-analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized trials of rosiglitazone.

Journal Article Clinical trials (London, England) · January 2008 BackgroundA meta-analysis of randomized controlled trials suggested that rosiglitazone, a drug used for the treatment of diabetes, may be associated with an increased risk of cardiovascular adverse events. Three large randomized trials, designed s ... Full text Cite

Tamoxifen for the prevention of breast cancer development: an updated meta-analysis.

Conference BREAST CANCER RESEARCH AND TREATMENT · December 1, 2007 Link to item Cite