Joanne Kurtzberg

Jerome S. Harris Distinguished Professor of Pediatrics

Pediatrics, Transplant and Cellular Therapy

joanne.kurtzberg@duke.edu

Box 102501, Durham, NC 27710

2400 Pratt Street, DUMC Box 102501, Durham, NC 27710

More About This Person

At a Glance

Credentials
1. Education
2. Licensure

Academic Experience

Expertise

Research
1. Selected Grants

Publications
1. Selected Publications

Artistic Works / Events

Teaching

Advising & Mentoring

Recognition
1. In the News

Professional Activities

Selected Grants

Blood and Marrow Transplant Clinical Trials Network

Clinical TrialCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2001 - 2031

Tolerance to Allogeneic Hearts via Implantation of Cultured Donor Thymus

ResearchAdvisor · Awarded by National Institutes of Health · 2025 - 2028

HRSA National Cord Blood Inventory, Fifth Cohort

ResearchPrincipal Investigator · Awarded by Health Resources and Service Administration · 2015 - 2028

Developing a Novel Umbilical Cord Blood-Derived Cell Therapy to Suppress Neuroinflammation and Promote Remyelination

ResearchCollaborator · Awarded by Department of Defense · 2025 - 2028

A Phase 1b Clinical Study of Intravenous AAVrh10 Vector Expressing GALC in Krabbe Subjects Who Previously Received Hematopoietic Stem Cell Transplantation (REKLAIM)

Clinical TrialPrincipal Investigator · Awarded by Forge Biologics · 2024 - 2026

Inducing Xenotolerance via Chimeric Thymus

ResearchCollaborator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2026

NMDP / Be the Match Biobank

ResearchPrincipal Investigator · Awarded by National Marrow Donor Program · 2019 - 2026

NIH HEAL initiative: A first-in-class, mechanism-guided, cell-based therapy for complex regional pain syndrome

ResearchPrincipal Investigator · Awarded by Cleveland Clinic Lerner College of Medicine · 2022 - 2026

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 1975 - 2026

Transplantation of Cryopreserved Thymus

ResearchAdvisor · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2026

2025 Leukodystrophy Care Network Center Certification Agreement

Public ServicePrincipal Investigator · Awarded by Hunter's Hope Foundation, Inc. · 2023 - 2026

NDMP Cord Blood Process Improvement Agreement

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2024 - 2025

MS Clinical Trial: DUOC

ResearchPrincipal Investigator · Awarded by The Marcus Foundation · 2020 - 2025

Follow-up on CBU samples collaboration

ResearchPrincipal Investigator · Awarded by National Institute of Environmental Health Sciences · 2024 - 2025

Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRL-ALT-D) BMT CTN Protocol #1702

Clinical TrialPrincipal Investigator · Awarded by National Marrow Donor Program · 2019 - 2024

Extension for IMPACT Phase 2 Clinical Trial

Clinical TrialInvestigator · Awarded by CryoCell International · 2022 - 2024

High Fidelity Diffusion MRI for Children with Cerebral Palsy in Stem Cell Therapy

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2023

Marcus Foundation Grant Agreement

ResearchPrincipal Investigator · Awarded by The Marcus Foundation · 2014 - 2023

Creation of a Longitudinal Krabbe Disease Clinical Research Database

ResearchPrincipal Investigator · Awarded by Neurogene, Inc. · 2021 - 2023

2022 Leukodystrophy Care Network Center Certification Agreement

Public ServicePrincipal Investigator · Awarded by Hunter's Hope Foundation, Inc. · 2022 - 2022

Pilot Study of Safety and Efficacy of Cord Tissue Derived Mesenchymal Stromal Cells (hCT-MSC) in COVID-19 Related Acute Respiratory Distress Syndrome (ARDS)

Clinical TrialPrincipal Investigator · Awarded by The Marcus Foundation · 2020 - 2022

Marcus Foundation Phase II MSC ASD

ResearchPrincipal Investigator · Awarded by The Marcus Foundation · 2019 - 2022

T32 UNC - Duke Immunotherapy Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by University of North Carolina - Chapel Hill · 2021 - 2022

A High-Performance 3T MRI for Brain Imaging

EquipmentMajor User · Awarded by National Institutes of Health · 2021 - 2022

Reprogramming Inflammatory Cells with Mesenchymal Stromal Cell RNA Granules

ResearchMentor · Awarded by Cord Blood Association Foundation · 2019 - 2022

2021 Leukodystrophy Care Network Center Certification Agreement

Public ServicePrincipal Investigator · Awarded by Hunter's Hope Foundation, Inc. · 2021 - 2021

RVT 802: FDA BLA Support (Addendum #23)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2020 - 2021

Phase I clinical trial for the use of hCT-MSc in children with COVID-19

Clinical TrialPrincipal Investigator · Awarded by The Marcus Foundation · 2020 - 2021

Recruitment HLA Typing of Genetically Diverse Cord Blood Units

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2021 - 2021

Cord Blood Collection Agreement #141239

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2020 - 2021

Transmission electron microscope (TEM)

EquipmentMinor User · Awarded by National Institutes of Health · 2019 - 2021

Data Enabled Automation for the Improved Efficiency, Yield, and Reproducibility of the Manufacturing of Human Umbilical Cord Tissue Mesenchymal Stromal Cells for Clinical Therapeutic Use

ResearchPrincipal Investigator · Awarded by Georgia Institute of Technology · 2018 - 2021

Hypoxic Ischemic Encephalopathy-Phase II-Robertson Foundation

Clinical TrialPrincipal Investigator · Awarded by Robertson Foundation · 2015 - 2021

HLA Typing and Release Testing Addendum

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2020 - 2020

RVT 802: Research Thymus Manufacturing (Addend #19)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2019 - 2020

Optimized Procedures and SOP's for Thymus Tissue Processing

Clinical TrialPrincipal Investigator · Awarded by Orphavant Sciences GmbH · 2017 - 2020

Comparing Reduced Intensity Allo HCT to Hypomethylating Therapy or Best Supportive Care in Patients Aged 50-75 with Intermediate-2 and High Risk Myelodysplastic Syndrome

Clinical TrialPrincipal Investigator · Awarded by National Marrow Donor Program · 2014 - 2020

Reduced-Intensity Conditioning for Children and Adults with Hemophagocytic Syndromes or Reduced-Intensity Conditioning for Children and Adults with Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (RICHI)

Clinical TrialPrincipal Investigator · Awarded by National Marrow Donor Program · 2014 - 2020

Tissue Collection and Processing for Thymus Transplantation

Clinical TrialPrincipal Investigator · Awarded by Orphavant Sciences GmbH · 2017 - 2020

Notch Mediated Expansion of Cord Blood Progenitors for Stem Cell Transplant

Clinical TrialPrincipal Investigator · Awarded by Fred Hutchinson Cancer Research Center · 2017 - 2020

2018 Cord Blood Collection Agreement

ResearchPrincipal Investigator · Awarded by National Marrow Donor Program · 2018 - 2019

RVT 802: Media Fill and FDA Response (Addend #20)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2019 - 2019

Enzyvant Sub Award Vendors (Addend #18)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2019 - 2019

NMDP / Be the Match Biobank

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2019 - 2019

RVT 802: Media Fill and FDA Response (Addend #17)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2019 - 2019

HRSA National Cord Blood Inventory

ResearchPrincipal Investigator · Awarded by Health Resources and Service Administration · 2006 - 2019

Creation of Storage Space Dedicated to RVT-802 (Project Addendum #15)

Construction/RenovationPrincipal Investigator · Awarded by Enzyvant · 2018 - 2019

Raw Materials Testing (Project Addendum #16)

ResearchPrincipal Investigator · Awarded by Enzyvant · 2018 - 2019

Purchase of Environmental Monitoring (EM) Equipment (Project Addendum #14)

EquipmentPrincipal Investigator · Awarded by Enzyvant · 2018 - 2019

Potency and Release Assays for Thymus Tissue Processing

ResearchPrincipal Investigator · Awarded by Orphavant Sciences GmbH · 2017 - 2019

Duke-UNC Clinical Hematology and Transfusion Research Career Development Program

ResearchMentor · Awarded by National Institutes of Health · 2006 - 2019

A Phase I Trial of a Single ProHema CB Product (Ex Vivo Modulated Human Cord Blood Cells) as Part of Single Cord Blood Unit Transplant after Busulfan/Cyclophosphamide/ATG Conditioning for Pediatric Patients with Inherited Metabolic Disorders

Clinical TrialPrincipal Investigator · Awarded by Fate Therapeutics · 2015 - 2019

A Single-arm, Prospective Study of Remestemcel-L, Ex-Vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Patients who have Failed to Respond to Steroid Treatment for Acute GVHD

Clinical TrialPrincipal Investigator · Awarded by Mesoblast International Sarl · 2015 - 2018

Safety Follow-up Through 180 Days of Treatment with Remestemcel-L in Study MSB-GVHD001 in Pediatric Patients who have Failed to Respond to Steroid Treatment for Acute GVHD

Clinical TrialPrincipal Investigator · Awarded by Mesoblast International Sarl · 2015 - 2018

Duke Research Training Program for Pediatricians

Inst. Training Prgm or CMETraining Manager · Awarded by National Institutes of Health · 2002 - 2018

(TEACH) Atemtuzumab, Costimulation Blockade and Sirolimus: A Tolerogenic Canvas for Donor Antigen Delivery via Mesenchymal

ResearchInvestigator · Awarded by Benaroya Research Institute at Virginia Mason · 2014 - 2018