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Kyle Jason Rehder

Dr. Glenn A. Kiser and Eltha Muriel Kiser Professor of Pediatrics
Pediatrics, Critical Care Medicine
Dept of Pediatrics, Box 3046 DUMC, Durham, NC 27710

Selected Publications


Ketamine Use in the Intubation of Critically Ill Children with Neurological Indications: A Multicenter Retrospective Analysis.

Journal Article Neurocritical care · February 2024 BackgroundKetamine has traditionally been avoided for tracheal intubations (TIs) in patients with acute neurological conditions. We evaluate its current usage pattern in these patients and any associated adverse events.MethodsWe conducted ... Full text Cite

Association Between Dead Space to Tidal Volume Ratio and Duration of Respiratory Support After Extubation in Critically Ill Children.

Journal Article Respir Care · November 2023 BACKGROUND: The dead-space-to-tidal-volume ratio (VD/VT) has been used to successfully predict extubation failure in children who are critically ill. However, a singular reliable measure to predict the level and duration of respiratory support after libera ... Full text Link to item Cite

Characteristics, Identification, Training, and Perception of Leaders in Respiratory Care.

Journal Article Respir Care · October 2023 BACKGROUND: Leadership is critical to high-functioning teams; however, data are lacking for what defines successful respiratory therapist (RT) leadership. Leaders need a wide range of skills to be successful, although the exact characteristics, behaviors, ... Full text Link to item Cite

Implementation of Video Laryngoscope-Assisted Coaching Reduces Adverse Tracheal Intubation-Associated Events in the PICU.

Journal Article Crit Care Med · July 1, 2023 OBJECTIVES: To evaluate implementation of a video laryngoscope (VL) as a coaching device to reduce adverse tracheal intubation associated events (TIAEs). DESIGN: Prospective multicenter interventional quality improvement study. SETTING: Ten PICUs in North ... Full text Link to item Cite

Mechanical Ventilation during ECMO: Best Practices.

Journal Article Respir Care · June 2023 Adults and children who require extracorporeal membrane oxygenation for respiratory failure remain at risk for ongoing lung injury if ventilator management is not optimized. This review serves as a guide to assist the bedside clinician in ventilator titrat ... Full text Link to item Cite

Enhancing Respiratory Therapists' Well-Being: Battling Burnout in Respiratory Care.

Journal Article Respir Care · May 2023 Burnout is a major problem in health care and is associated with adverse sequelae for patients, health care workers, and organizations. Burnout among respiratory therapists (RTs) is as high as 79% and is associated with poor or ineffective leadership, inad ... Full text Link to item Cite

Teamwork Before and During COVID-19: The Good, the Same, and the Ugly….

Journal Article J Patient Saf · January 1, 2023 OBJECTIVES: The COVID 19 pandemic placed unprecedented strain on healthcare systems and workers, likely also impacting patient safety and outcomes. This study aimed to understand how teamwork climate changed during that pandemic and how these changes affec ... Full text Open Access Link to item Cite

Strengthening patient-family engagement amidst a pandemic: Lessons learned and paths forward

Journal Article Patient Experience Journal · January 1, 2023 The COVID-19 pandemic was highly disruptive to healthcare and negatively affected healthcare worker and patient experience on multiple levels. Patient Family Advisors serve an important role in partnering with health systems to improve patient experience, ... Full text Cite

Burnout Among Respiratory Therapists Amid the COVID-19 Pandemic.

Journal Article Respir Care · December 2022 BACKGROUND: Burnout is a major challenge in health care and is associated with poor overall well-being, increased medical errors, worse patient outcomes, and low job satisfaction. There is scant literature focused on the respiratory therapist's (RT) experi ... Full text Link to item Cite

Factors Associated With a Positive View of Respiratory Care Leadership.

Journal Article Respir Care · October 2022 BACKGROUND: Burnout within health care is prevalent, and its effects are detrimental to patient outcomes, organizations, and individuals. Effects stemming from burnout include anxiety, depression, excessive alcohol and drug use, cardiovascular problems, ti ... Full text Link to item Cite

The Psychological Safety Scale of the Safety, Communication, Operational, Reliability, and Engagement (SCORE) Survey: A Brief, Diagnostic, and Actionable Metric for the Ability to Speak Up in Healthcare Settings.

Journal Article J Patient Saf · September 1, 2022 OBJECTIVES: The current study aimed to guide the assessment and improvement of psychological safety (PS) by (1) examining the psychometric properties of a brief novel PS scale, (2) assessing relationships between PS and other safety culture domains, (3) ex ... Full text Open Access Link to item Cite

Mechanical Ventilation and Respiratory Support in the Pediatric Intensive Care Unit.

Journal Article Pediatr Clin North Am · June 2022 Children admitted to the pediatric intensive care unit often require respiratory support for the treatment of respiratory distress and failure. Respiratory support comprises both noninvasive modalities (ie, heated humidified high-flow nasal cannula, contin ... Full text Link to item Cite

Extracorporeal membrane oxygenation in critically ill neonatal and pediatric patients with acute respiratory failure: a guide for the clinician.

Journal Article Expert Rev Respir Med · October 2021 Intro: Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure continues to demonstrate improving outcomes, largely due to advances in technology along with refined management strategies despite mounting patient acuity and comple ... Full text Link to item Cite

The Science of Health Care Worker Burnout: Assessing and Improving Health Care Worker Well-Being.

Journal Article Arch Pathol Lab Med · September 1, 2021 CONTEXT.—: Problems with health care worker (HCW) well-being have become a leading concern in medicine given their severity and robust links to outcomes like medical error, mortality, and turnover. OBJECTIVE.—: To describe the state of the science regardin ... Full text Open Access Link to item Cite

Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT).

Journal Article Chest · September 2021 BACKGROUND: The use of electronic clinical decision support (CDS) systems for pediatric critical care trials is rare. We sought to describe in detail the use of a CDS tool (Children's Hospital Euglycemia for Kids Spreadsheet [CHECKS]), for the management o ... Full text Link to item Cite

High-Flow Nasal Cannula in Pediatric Critical Asthma.

Journal Article Respir Care · August 2021 BACKGROUND: High-flow nasal cannula (HFNC) has been used in the treatment of pediatric asthma, although high-quality data comparing HFNC to aerosol mask nebulizer are lacking. We hypothesized that HFNC would perform similarly to the aerosol mask for meanin ... Full text Link to item Cite