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Kyra Leigh McCarty

Assistant Professor of Pediatrics
Pediatrics, Hematology-Oncology
DUMC 102382, Durham, NC 27705
2301 Erwin Road, Durham, NC 27705

Research Interests


Predicting asparaginase hypersensitivity reactions in pediatric lymphoblastic leukemia. Ten-year retrospective chart review examining the potential ethnic and genetic associations with incidence of hypersensitivity reactions to asparaginase in pediatric patients with acute leukemia. IRB #STU-2023-1073 (UTSW).
Understanding CNS disease in infant lymphoblastic leukemia. Twenty-year retrospective chart review examining the varied treatment plans and CNS-directed therapies utilized in cases of infant leukemia to better understand the prognostic impact of CNS disease in infants with acute lymphoblastic leukemia. IRB #STU-2025-0370 (UTSW).


Fellowships, Gifts, and Supported Research


Investigator Sponsored Trial Grant · 2024 Awarded by: Jazz Pharmaceuticals Investigator sponsored trial examining the patient demographic and genetic factors associated with hypersensitivity to asparaginase, a chemotherapeutic agent used in the treatment of pediatric lymphoblastic leukemia. This grant funds whole genome sequencing for patient samples and biostatical support for data analysis.

External Relationships


  • Jazz Pharmaceuticals

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.