Laine Elliott Thomas | Scholars@Duke

Laine Elliott Thomas
Professor of Biostatistics & Bioinformatics

Causal Inference, Heterogeneity of Treatment Effects, Observational Data, Time-varying Treatments, Real World Evidence

Current Appointments & Affiliations

Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2022
Associate Director, DCRI Biostatistics, Biostatistics & Bioinformatics, Basic Science Departments 2018
Associate Chair for Diversity and Inclusion in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2020
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2009

Contact Information

200 Morris Street, 7812 200 Morris, Durham, NC 27701
Duke Box 3850, Durham, NC 27710
laine.thomas@duke.edu (919) 684-1289

Background
Education, Training, & Certifications
- Ph.D., North Carolina State University 2009
Previous Appointments & Affiliations
- Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2021 - 2022
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2018 - 2020
- Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2009 - 2018
Leadership & Clinical Positions at Duke
- Associate Director, Biostatistics at the DCRI
Expertise
Global Scholarship
- Research
  - Denmark (Country)
Research
Selected Grants
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2022 - 2027
- Innovative Biostatistical Methods for Analysis and Assessment of Clinical Trials Augmented by Real World Data awarded by Burroughs Wellcome Fund 2021 - 2026
- New causal inference methods for cluster randomized trials with post-randomization selection awarded by Patient Centered Outcomes Research Institute 2020 - 2024
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2013 - 2024
- HERO Program, HERO Registry, HERO-HCQ Trial awarded by Patient Centered Outcomes Research Institute 2020 - 2023
- Methods for the Design and Conduct of Subgroup Analysis in Observational Studies awarded by Patient Centered Outcomes Research Institute 2019 - 2022
- CHAMP-HF awarded by Novartis Pharmaceuticals Corporation 2016 - 2022
- Hero Ancillary Study: The Nurse HERO Study awarded by Children's Hospital of Philadelphia 2021
- GARFIELD-Atrial Fibrillation Registry Research awarded by Thrombosis Research Institute 2016 - 2020
- Statistical Methods for Complex Data in Cardiovascular Disease awarded by North Carolina State University 2013 - 2018
- Matching Methods for Comparative Effectiveness Studies of Longitudinal Treatments awarded by Agency for Healthcare Research and Quality 2015 - 2017
- NCDR-ACTION awarded by American College of Cardiology Foundation 2008 - 2015
External Relationships
- AstraZeneca
- InQuera
- JAMA
- Merck
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Chen-Lim ML, McCabe MA, Xu H, Thomas LE, Forrest CB, Birnbaum S, et al. Experiences of U.S. Nurses Compared With Nonnurses in the First Year of COVID-19: Findings From a National Registry. Nurs Res. 2022 Nov;71(6):421–31.
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  - Pokorney SD, Berchuck SI, Chiswell K, Sun J-L, Thomas L, Jones WS, et al. Atrial branch coronary artery stenosis as a mechanism for atrial fibrillation. Heart Rhythm. 2022 Aug;19(8):1237–44.
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  - Bahit MC, Vora AN, Li Z, Wojdyla DM, Thomas L, Goodman SG, et al. Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke: A Post Hoc Analysis From the AUGUSTUS Trial. Jama Cardiol. 2022 Jul 1;7(7):682–9.
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  - Chapman B, Hellkamp AS, Thomas LE, Albert NM, Butler J, Patterson JH, et al. Angiotensin Receptor Neprilysin Inhibition and Associated Outcomes by Race and Ethnicity in Patients With Heart Failure With Reduced Ejection Fraction: Data From CHAMP-HF. J Am Heart Assoc. 2022 Jun 20;11(12):e022889.
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  - Cheng C, Li F, Thomas LE, Li FF. Addressing Extreme Propensity Scores in Estimating Counterfactual Survival Functions via the Overlap Weights. Am J Epidemiol. 2022 May 20;191(6):1140–51.
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  - DeVore AD, Hellkamp AS, Thomas L, Albert NM, Butler J, Patterson JH, et al. The association of improvement in left ventricular ejection fraction with outcomes in patients with heart failure with reduced ejection fraction: data from CHAMP-HF. Eur J Heart Fail. 2022 May;24(5):762–70.
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  - Wise LA, Thomas L, Anderson S, Baird DD, Anchan RM, Terry KL, et al. Route of myomectomy and fertility: a prospective cohort study. Fertil Steril. 2022 May;117(5):1083–93.
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  - Greene SJ, Butler J, Hellkamp AS, Spertus JA, Vaduganathan M, Devore AD, et al. Comparative Effectiveness of Dosing of Medical Therapy for Heart Failure: From the CHAMP-HF Registry. J Card Fail. 2022 Mar;28(3):370–84.
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  - Zhou T, Tong G, Li F, Thomas LE. PSweight: An R Package for Propensity ScoreWeighting Analysis. R Journal. 2022 Mar 1;14(1):282–99.
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  - Harskamp RE, Fanaroff AC, Lopes RD, Wojdyla DM, Goodman SG, Thomas LE, et al. Antithrombotic Therapy in Patients With Atrial Fibrillation After Acute Coronary Syndromes or Percutaneous Intervention. J Am Coll Cardiol. 2022 Feb 8;79(5):417–27.
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  - DeVore AD, Hill CL, Thomas LE, Albert NM, Butler J, Patterson JH, et al. Identifying patients at increased risk for poor outcomes from heart failure with reduced ejection fraction: the PROMPT-HF risk model. Esc Heart Fail. 2022 Feb;9(1):178–85.
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  - Vaduganathan M, Fonarow GC, Greene SJ, Devore AD, Albert NM, Duffy CI, et al. Treatment Persistence of Renin-Angiotensin-Aldosterone-System Inhibitors Over Time in Heart Failure with Reduced Ejection Fraction. J Card Fail. 2022 Feb;28(2):191–201.
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  - Farjat AE, Virdone S, Thomas LE, Kakkar AK, Pieper KS, Piccini JP. The importance of the design of observational studies in comparative effectiveness research: Lessons from the GARFIELD-AF and ORBIT-AF registries. Am Heart J. 2022 Jan;243:110–21.
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  - Rymer JA, Li S, Pun PH, Thomas L, Wang TY. Racial Disparities in Invasive Management for Patients With Acute Myocardial Infarction With Chronic Kidney Disease. Circ Cardiovasc Interv. 2022 Jan;15(1):e011171.
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  - Khan MS, Greene SJ, Hellkamp AS, DeVore AD, Shen X, Albert NM, et al. Diuretic Changes, Health Care Resource Utilization, and Clinical Outcomes for Heart Failure With Reduced Ejection Fraction: From the Change the Management of Patients With Heart Failure Registry. Circ Heart Fail. 2021 Nov;14(11):e008351.
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  - Thomas LE, Navar AM, Pencina MJ. Extrapolating Survival From Randomized Clinical Trial Data-Possibilities and Caution. Jama Cardiol. 2021 Nov 1;6(11):1305–7.
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  - Tran AT, Fonarow GC, Arnold SV, Jones PG, Thomas LE, Hill CL, et al. Risk Adjustment Model for Preserved Health Status in Patients With Heart Failure and Reduced Ejection Fraction: The CHAMP-HF Registry. Circ Cardiovasc Qual Outcomes. 2021 Oct;14(10):e008072.
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  - Yang S, Li F, Thomas LE. Covariate adjustment in subgroup analyses of randomized clinical trials: A propensity score approach. Clin Trials. 2021 Oct;18(5):570–81.
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  - Etherton MR, Shah S, Haolin X, Xian Y, Maisch L, Hannah D, et al. Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors. Stroke Vasc Neurol. 2021 Sep;6(3):384–94.
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  - Jackson LR, Schrader P, Thomas L, Steinberg BA, Blanco R, Allen LA, et al. Dosing of Direct Oral Anticoagulants in Patients with Moderate Chronic Kidney Disease in US Clinical Practice: Results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF II). Am J Cardiovasc Drugs. 2021 Sep;21(5):553–61.
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  - Yang S, Lorenzi E, Papadogeorgou G, Wojdyla DM, Li F, Thomas LE. Propensity score weighting for causal subgroup analysis. Stat Med. 2021 Aug 30;40(19):4294–309.
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  - Thomas LE, Turakhia MP, Pencina MJ. Competing Risks, Treatment Switching, and Informative Censoring. Jama Cardiol. 2021 Aug 1;6(8):871–3.
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  - Lopes RD, Thomas L, Di Fusco M, Keshishian A, Luo X, Li X, et al. Clinical and Economic Outcomes Among Nonvalvular Atrial Fibrillation Patients With Coronary Artery Disease and/or Peripheral Artery Disease. Am J Cardiol. 2021 Jun 1;148:69–77.
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  - Forrest CB, Xu H, Thomas LE, Webb LE, Cohen LW, Carey TS, et al. Impact of the Early Phase of the COVID-19 Pandemic on US Healthcare Workers: Results from the HERO Registry. J Gen Intern Med. 2021 May;36(5):1319–26.
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  - Albert NM, Tyson RJ, Hill CL, DeVore AD, Spertus JA, Duffy C, et al. Variation in use and dosing escalation of renin angiotensin system, mineralocorticoid receptor antagonist, angiotensin receptor neprilysin inhibitor and beta-blocker therapies in heart failure and reduced ejection fraction: Association of comorbidities. Am Heart J. 2021 May;235:82–96.
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  - Greene SJ, Butler J, Spertus JA, Hellkamp AS, Vaduganathan M, DeVore AD, et al. Comparison of New York Heart Association Class and Patient-Reported Outcomes for Heart Failure With Reduced Ejection Fraction. Jama Cardiol. 2021 May 1;6(5):522–31.
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  - Shen L, Xian Y, Chen AY, Thomas L, Roe MT, Peterson ED, et al. Effect of intervention timing on one-year mortality in elderly non-ST-segment elevation myocardial infarction patients. Coron Artery Dis. 2021 Mar 1;32(2):138–44.
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  - Wegienka G, Stewart EA, Nicholson WK, Zhang S, Li F, Thomas L, et al. Black Women Are More Likely Than White Women to Schedule a Uterine-Sparing Treatment for Leiomyomas. J Womens Health (Larchmt). 2021 Mar;30(3):355–66.
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  - Khariton Y, Fonarow GC, Hellkamp A, Thomas L, Nassif ME, Butler J, et al. Heterogeneity of health status treatment response with sacubitril/valsartan: insights from the CHAMP-HF registry. Esc Heart Fail. 2021 Feb;8(1):710–3.
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  - Li F, Thomas LE. RE:"ADDRESSING EXTREME PROPENSITY SCORES VIA THE OVERLAP WEIGHTS". Am J Epidemiol. 2021 Jan 4;190(1):189–90.
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  - Wosik J, Clowse MEB, Overton R, Adagarla B, Economou-Zavlanos N, Cavalier J, et al. Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care. Am Heart J. 2021 Jan;231:1–5.
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  - Srivastava PK, DeVore AD, Hellkamp AS, Thomas L, Albert NM, Butler J, et al. Heart Failure Hospitalization and Guideline-Directed Prescribing Patterns Among Heart Failure With Reduced Ejection Fraction Patients. Jacc Heart Fail. 2021 Jan;9(1):28–38.
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  - Mentz RJ, Xu H, O’Brien EC, Thomas L, Alexy T, Gupta B, et al. PROVIDE-HF primary results: Patient-Reported Outcomes inVestigation following Initiation of Drug therapy with Entresto (sacubitril/valsartan) in heart failure. Am Heart J. 2020 Dec;230:35–43.
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  - Zhou Y, Matsouaka RA, Thomas L. Propensity score weighting under limited overlap and model misspecification. Stat Methods Med Res. 2020 Dec;29(12):3721–56.
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  - Thomas LE, Bonow RO, Pencina MJ. Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19). Jama Cardiol. 2020 Sep 1;5(9):988–90.
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  - Jackson LR, Kim S, Blanco R, Thomas L, Ansell J, Fonarow GC, et al. Discontinuation rates of warfarin versus direct acting oral anticoagulants in US clinical practice: Results from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II). Am Heart J. 2020 Aug;226:85–93.
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  - Thomas LE, Yang S, Wojdyla D, Schaubel DE. Matching with time-dependent treatments: A review and look forward. Stat Med. 2020 Jul 30;39(17):2350–70.
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  - DeVore AD, Hellkamp AS, Thomas L, Albert NM, Butler J, Patterson JH, et al. Improvement in Left Ventricular Ejection Fraction in Outpatients With Heart Failure With Reduced Ejection Fraction: Data From CHAMP-HF. Circ Heart Fail. 2020 Jul;13(7):e006833.
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  - Thomas LE, Li F, Pencina MJ. Overlap Weighting: A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Jama. 2020 Jun 16;323(23):2417–8.
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  - Vaduganathan M, Fonarow GC, Greene SJ, DeVore AD, Kavati A, Sikirica S, et al. Contemporary Treatment Patterns and Clinical Outcomes of Comorbid Diabetes Mellitus and HFrEF: The CHAMP-HF Registry. Jacc Heart Fail. 2020 Jun;8(6):469–80.
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  - Alexander JH, Wojdyla D, Vora AN, Thomas L, Granger CB, Goodman SG, et al. Risk/Benefit Tradeoff of Antithrombotic Therapy in Patients With Atrial Fibrillation Early and Late After an Acute Coronary Syndrome or Percutaneous Coronary Intervention: Insights From AUGUSTUS. Circulation. 2020 May 19;141(20):1618–27.
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  - Thomas LE, Bonow RO, Pencina MJ. Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19). Jama Cardiol. 2020 May 5;
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  - Laughlin-Tommaso SK, Lu D, Thomas L, Diamond M, Wallace K, Wegienka G, et al. Short-term quality of life after myomectomy for uterine fibroids from the compare-uf fibroid registry. Obstetrical and Gynecological Survey. 2020 May 1;75(5):285–7.
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  - Laughlin-Tommaso SK, Lu D, Thomas L, Diamond MP, Wallace K, Wegienka G, et al. Short-term quality of life after myomectomy for uterine fibroids from the COMPARE-UF Fibroid Registry. Am J Obstet Gynecol. 2020 Apr;222(4):345.e1-345.e22.
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  - Pokorney SD, Black-Maier E, Hellkamp AS, Friedman DJ, Vemulapalli S, Granger CB, et al. Oral Anticoagulation and Cardiovascular Outcomes in Patients With Atrial Fibrillation and End-Stage Renal Disease. J Am Coll Cardiol. 2020 Mar 24;75(11):1299–308.
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  - Lopes RD, Leonardi S, Wojdyla DM, Vora AN, Thomas L, Storey RF, et al. Stent Thrombosis in Patients With Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial. Circulation. 2020 Mar 3;141(9):781–3.
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  - Wallace K, Zhang S, Thomas L, Stewart EA, Nicholson WK, Wegienka GR, et al. Comparative effectiveness of hysterectomy versus myomectomy on one-year health-related quality of life in women with uterine fibroids. Fertil Steril. 2020 Mar;113(3):618–26.
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  - Thomas L, Li F, Pencina M. Using Propensity Score Methods to Create Target Populations in Observational Clinical Research. Jama. 2020 Feb 4;323(5):466–7.
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  - Pokorney SD, Holmes DN, Shrader P, Thomas L, Fonarow GC, Mahaffey KW, et al. Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation. Am Heart J. 2020 Feb;220:145–54.
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  - Loring Z, Shrader P, Allen LA, Blanco R, Chan PS, Ezekowitz MD, et al. Guideline-directed therapies for comorbidities and clinical outcomes among individuals with atrial fibrillation. Am Heart J. 2020 Jan;219:21–30.
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  - Vaduganathan M, Fonarow GC, Greene SJ, DeVore AD, Albert NM, Duffy CI, et al. Health-Related Quality of Life in Comorbid Heart Failure With Reduced Ejection Fraction and Diabetes Mellitus. J Am Coll Cardiol. 2019 Dec 24;74(25):3176–8.
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  - Giblin EM, Adams KF, Hill L, Fonarow GC, Williams FB, Sharma PP, et al. Comparison of Hydralazine/Nitrate and Angiotensin Receptor Neprilysin Inhibitor Use Among Black Versus Nonblack Americans With Heart Failure and Reduced Ejection Fraction (from CHAMP-HF). Am J Cardiol. 2019 Dec 15;124(12):1900–6.
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  - Zullig LL, Jazowski SA, Wang TY, Hellkamp A, Wojdyla D, Thomas L, et al. Novel application of approaches to predicting medication adherence using medical claims data. Health Serv Res. 2019 Dec;54(6):1255–62.
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  - Khariton Y, Fonarow GC, Arnold SV, Hellkamp A, Nassif ME, Sharma PP, et al. Association Between Sacubitril/Valsartan Initiation and Health Status Outcomes in Heart Failure With Reduced Ejection Fraction. Jacc Heart Fail. 2019 Nov;7(11):933–41.
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  - Rymer JA, Chen AY, Thomas L, Fonarow GC, Peterson ED, Wang TY. Readmissions After Acute Myocardial Infarction: How Often Do Patients Return to the Discharging Hospital? J Am Heart Assoc. 2019 Oct;8(19):e012059.
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  - Xian Y, Xu H, O’Brien EC, Shah S, Thomas L, Pencina MJ, et al. Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study. Jama Neurol. 2019 Oct 1;76(10):1192–202.
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  - Fanaroff AC, Vora AN, Chen AY, Mathews R, Udell JA, Roe MT, et al. Hospital participation in clinical trials for patients with acute myocardial infarction: Results from the National Cardiovascular Data Registry. Am Heart J. 2019 Aug;214:184–93.
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  - Nicholson WK, Wegienka G, Zhang S, Wallace K, Stewart E, Laughlin-Tommaso S, et al. Short-Term Health-Related Quality of Life After Hysterectomy Compared With Myomectomy for Symptomatic Leiomyomas. Obstet Gynecol. 2019 Aug;134(2):261–9.
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  - Pokorney SD, Holmes DN, Thomas L, Fonarow GC, Kowey PR, Reiffel JA, et al. Association Between Warfarin Control Metrics and Atrial Fibrillation Outcomes in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation. Jama Cardiol. 2019 Aug 1;4(8):756–64.
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  - Guimarães PO, Lopes RD, Alexander JH, Thomas L, Hellkamp AS, Hijazi Z, et al. International normalized ratio control and subsequent clinical outcomes in patients with atrial fibrillation using warfarin. J Thromb Thrombolysis. 2019 Jul;48(1):27–34.
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  - Thomas M, Khariton Y, Fonarow GC, Arnold SV, Hill L, Nassif ME, et al. Association of Changes in Heart Failure Treatment With Patients' Health Status: Real-World Evidence From CHAMP-HF. Jacc Heart Fail. 2019 Jul;7(7):615–25.
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  - Shavadia JS, Holmes DN, Thomas L, Peterson ED, Granger CB, Roe MT, et al. Comparative Effectiveness of β-Blocker Use Beyond 3 Years After Myocardial Infarction and Long-Term Outcomes Among Elderly Patients. Circ Cardiovasc Qual Outcomes. 2019 Jul;12(7):e005103.
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  - Thomas LE, O’Brien EC, Piccini JP, D’Agostino RB, Pencina MJ. Application of net reclassification index to non-nested and point-based risk prediction models: a review. Eur Heart J. 2019 Jun 14;40(23):1880–7.
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  - Greene SJ, Fonarow GC, DeVore AD, Sharma PP, Vaduganathan M, Albert NM, et al. Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction. J Am Coll Cardiol. 2019 May 21;73(19):2365–83.
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  - Vemulapalli S, Inohara T, Kim S, Thomas L, Piccini JP, Patel MR, et al. Blood Pressure Control and Cardiovascular Outcomes in Patients With Atrial Fibrillation (From the ORBIT-AF Registry). Am J Cardiol. 2019 May 15;123(10):1628–36.
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  - Perino AC, Shrader P, Turakhia MP, Ansell JE, Gersh BJ, Fonarow GC, et al. Comparison of Patient-Reported Care Satisfaction, Quality of Warfarin Therapy, and Outcomes of Atrial Fibrillation: Findings From the ORBIT - AF Registry. J Am Heart Assoc. 2019 May 7;8(9):e011205.
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  - Holmes DN, Piccini JP, Allen LA, Fonarow GC, Gersh BJ, Kowey PR, et al. Defining Clinically Important Difference in the Atrial Fibrillation Effect on Quality-of-Life Score. Circ Cardiovasc Qual Outcomes. 2019 May;12(5):e005358.
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  - Madhavan M, Holmes DN, Piccini JP, Ansell JE, Fonarow GC, Hylek EM, et al. Association of frailty and cognitive impairment with benefits of oral anticoagulation in patients with atrial fibrillation. Am Heart J. 2019 May;211:77–89.
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  - Peri-Okonny PA, Mi X, Khariton Y, Patel KK, Thomas L, Fonarow GC, et al. Target Doses of Heart Failure Medical Therapy and Blood Pressure: Insights From the CHAMP-HF Registry. Jacc Heart Fail. 2019 Apr;7(4):350–8.
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  - Thomas LE, Schulte PJ. Separating variability in healthcare practice patterns from random error. Stat Methods Med Res. 2019 Apr;28(4):1247–60.
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  - Doll JA, Hellkamp AS, Thomas L, Fonarow GC, Peterson E, Wang TY. The association of pre- and posthospital medication adherence in myocardial infarction patients. Am Heart J. 2019 Feb;208:74–80.
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  - O’Brien EC, Holmes DN, Thomas L, Singer DE, Fonarow GC, Mahaffey KW, et al. Incremental prognostic value of renal function for stroke prediction in atrial fibrillation. Int J Cardiol. 2019 Jan 1;274:152–7.
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  - Li F, Thomas LE. Addressing Extreme Propensity Scores via the Overlap Weights. Am J Epidemiol. 2019 Jan 1;188(1):250–7.
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  - Jackson LR, Kim S, Shrader P, Blanco R, Thomas L, Ezekowitz MD, et al. Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. J Thromb Thrombolysis. 2018 Nov;46(4):435–9.
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  - Arnold SV, Cohen DJ, Dai D, Jones PG, Li F, Thomas L, et al. Predicting Quality of Life at 1 Year After Transcatheter Aortic Valve Replacement in a Real-World Population. Circ Cardiovasc Qual Outcomes. 2018 Oct;11(10):e004693.
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  - Huffman MD, Thomas LE. Tools for Evaluating and Improving Causal Inference: Introducing JAMA Cardiology Readers to the Risk of Bias in Nonrandomized Studies of Interventions (ROBINS-I) Tool. Jama Cardiol. 2018 Oct 1;3(10):907.
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  - Washam JB, Holmes DN, Thomas LE, Pokorney SD, Hylek EM, Fonarow GC, et al. Pharmacotherapy for Atrial Fibrillation in Patients With Chronic Kidney Disease: Insights From ORBIT-AF. J Am Heart Assoc. 2018 Sep 18;7(18):e008928.
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  - Rymer JA, Chen AY, Thomas L, Stafford J, Enriquez JR, Goyal A, et al. Advanced Practice Provider Versus Physician-Only Outpatient Follow-Up After Acute Myocardial Infarction. J Am Heart Assoc. 2018 Sep 4;7(17):e008481.
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  - DeVore AD, Hill CL, Thomas L, Sharma PP, Albert NM, Butler J, et al. Patient, Provider, and Practice Characteristics Associated With Sacubitril/Valsartan Use in the United States. Circ Heart Fail. 2018 Sep;11(9):e005400.
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  - O’Brien EC, Li S, Thomas L, Wang TY, Roe MT, Peterson ED. The impact of clinical vs administrative claims coding on hospital risk-adjusted outcomes. Clin Cardiol. 2018 Sep;41(9):1225–31.
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  - O’Brien EC, Holmes DN, Thomas LE, Fonarow GC, Allen LA, Gersh BJ, et al. Prognostic Significance of Nuisance Bleeding in Anticoagulated Patients With Atrial Fibrillation. Circulation. 2018 Aug 28;138(9):889–97.
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  - Jackson LR, Kim S, Fonarow GC, Freeman JV, Gersh BJ, Go AS, et al. Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHA2DS2-VASc Scores: Findings From the ORBIT-AF I and II Registries. J Am Heart Assoc. 2018 Aug 21;7(16):e008764.
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  - Greene SJ, Butler J, Albert NM, DeVore AD, Sharma PP, Duffy CI, et al. Medical Therapy for Heart Failure With Reduced Ejection Fraction: The CHAMP-HF Registry. J Am Coll Cardiol. 2018 Jul 24;72(4):351–66.
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  - Stewart EA, Lytle BL, Thomas L, Wegienka GR, Jacoby V, Diamond MP, et al. The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design. Am J Obstet Gynecol. 2018 Jul;219(1):95.e1-95.e10.
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  - DeVore AD, Mi X, Thomas L, Sharma PP, Albert NM, Butler J, et al. Characteristics and Treatments of Patients Enrolled in the CHAMP-HF Registry Compared With Patients Enrolled in the PARADIGM-HF Trial. J Am Heart Assoc. 2018 Jun 12;7(12).
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  - O’Brien EC, Holmes DN, Thomas L, Fonarow GC, Kowey PR, Ansell JE, et al. Therapeutic Strategies Following Major, Clinically Relevant Nonmajor, and Nuisance Bleeding in Atrial Fibrillation: Findings From ORBIT-AF. J Am Heart Assoc. 2018 Jun 9;7(12).
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  - Udell JA, Desai NR, Li S, Thomas L, de Lemos JA, Wright-Slaughter P, et al. Neighborhood Socioeconomic Disadvantage and Care After Myocardial Infarction in the National Cardiovascular Data Registry. Circ Cardiovasc Qual Outcomes. 2018 Jun;11(6):e004054.
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  - Khariton Y, Nassif ME, Thomas L, Fonarow GC, Mi X, DeVore AD, et al. Health Status Disparities by Sex, Race/Ethnicity, and Socioeconomic Status in Outpatients With Heart Failure. Jacc Heart Fail. 2018 Jun;6(6):465–73.
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  - Fanaroff AC, Chen AY, Thomas LE, Pieper KS, Garratt KN, Peterson ED, et al. Risk Score to Predict Need for Intensive Care in Initially Hemodynamically Stable Adults With Non-ST-Segment-Elevation Myocardial Infarction. J Am Heart Assoc. 2018 May 25;7(11).
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  - Mathews R, Wang W, Kaltenbach LA, Thomas L, Shah RU, Ali M, et al. Hospital Variation in Adherence Rates to Secondary Prevention Medications and the Implications on Quality. Circulation. 2018 May 15;137(20):2128–38.
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  - Fudim M, Liu PR, Shrader P, Blanco RG, Allen LA, Fonarow GC, et al. Mineralocorticoid Receptor Antagonism in Patients With Atrial Fibrillation: Findings From the ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) Registry. J Am Heart Assoc. 2018 Apr 13;7(8).
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  - Khariton Y, Hernandez AF, Fonarow GC, Sharma PP, Duffy CI, Thomas L, et al. Health Status Variation Across Practices in Outpatients With Heart Failure: Insights From the CHAMP-HF (Change the Management of Patients With Heart Failure) Registry. Circ Cardiovasc Qual Outcomes. 2018 Apr;11(4):e004668.
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  - Pokorney SD, Yen DC, Campbell KB, Allen LaPointe NM, Sheng S, Thomas L, et al. Dofetilide dose reductions and discontinuations in women compared with men. Heart Rhythm. 2018 Apr;15(4):478–84.
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  - Lopes RD, Rordorf R, De Ferrari GM, Leonardi S, Thomas L, Wojdyla DM, et al. Digoxin and Mortality in Patients With Atrial Fibrillation. J Am Coll Cardiol. 2018 Mar 13;71(10):1063–74.
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  - Preiss D, Haffner SM, Thomas LE, Sun J-L, Sattar N, Yates T, et al. Change in levels of physical activity after diagnosis of type 2 diabetes: an observational analysis from the NAVIGATOR study. Diabetes Obes Metab. 2014 Dec;16(12):1265–8.
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  - Allen LA, Fonarow GC, Holmes DN, Thomas LE, Marzec LN, Pokorney SD, et al. Digoxin Use and Subsequent Outcomes Among Patients with and without Heart Failure in a Contemporary Atrial Fibrillation Cohort: Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). Circulation. 2014 Nov 25;130.
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  - Rymer J, McCoy LA, Thomas L, Peterson ED, Wang TY. Persistence of evidence-based medication use after discharge from academic versus nonacademic hospitals among patients with non-ST-segment elevation myocardial infarction. Am J Cardiol. 2014 Nov 15;114(10):1479–84.
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  - Thomas KL, Shah BR, Elliot-Bynum S, Thomas KD, Damon K, Allen LaPointe NM, et al. Check it, change it: a community-based, multifaceted intervention to improve blood pressure control. Circ Cardiovasc Qual Outcomes. 2014 Nov;7(6):828–34.
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  - de Barros e Silva PGM, Califf RM, Sun J-L, McMurray JJV, Holman R, Haffner S, et al. Chronic obstructive pulmonary disease and cardiovascular risk: insights from the NAVIGATOR trial. Int J Cardiol. 2014 Oct 20;176(3):1126–8.
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  - Flaker G, Lopes RD, Hylek E, Wojdyla DM, Thomas L, Al-Khatib SM, et al. Amiodarone, anticoagulation, and clinical events in patients with atrial fibrillation: insights from the ARISTOTLE trial. J Am Coll Cardiol. 2014 Oct 14;64(15):1541–50.
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  - O’Brien EC, Simon DN, Allen LA, Singer DE, Fonarow GC, Kowey PR, et al. Reasons for warfarin discontinuation in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). Am Heart J. 2014 Oct;168(4):487–94.
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  - Mathews R, Chen AY, Thomas L, Wang TY, Chin CT, Thomas KL, et al. Differences in short-term versus long-term outcomes of older black versus white patients with myocardial infarction: findings from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of American College of Cardiology/American Heart Association Guidelines (CRUSADE). Circulation. 2014 Aug 19;130(8):659–67.
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  - Steinberg BA, Blanco RG, Ollis D, Kim S, Holmes DN, Kowey PR, et al. Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II: rationale and design of the ORBIT-AF II registry. Am Heart J. 2014 Aug;168(2):160–7.
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  - Halvorsen S, Atar D, Yang H, De Caterina R, Erol C, Garcia D, et al. Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial. Eur Heart J. 2014 Jul 21;35(28):1864–72.
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  - Beatty AL, Li S, Thomas L, Amsterdam EA, Alexander KP, Whooley MA. Trends in referral to cardiac rehabilitation after myocardial infarction: data from the National Cardiovascular Data Registry 2007 to 2012. J Am Coll Cardiol. 2014 Jun 17;63(23):2582–3.
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  - Shen L, Thomas L, Shah BR. Response to letter to the editor by Lin et al. Am Heart J. 2014 Jun;167(6):e21.
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  - Hylek EM, Held C, Alexander JH, Lopes RD, De Caterina R, Wojdyla DM, et al. Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): Predictors, Characteristics, and Clinical Outcomes. J Am Coll Cardiol. 2014 May 27;63(20):2141–7.
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  - Steinberg BA, Kim S, Thomas L, Fonarow GC, Hylek E, Ansell J, et al. Lack of concordance between empirical scores and physician assessments of stroke and bleeding risk in atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. Circulation. 2014 May 20;129(20):2005–12.
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  - O’Brien E, Subherwal S, Roe MT, Holmes DN, Thomas L, Alexander KP, et al. Do patients treated at academic hospitals have better longitudinal outcomes after admission for non-ST-elevation myocardial infarction? Am Heart J. 2014 May;167(5):762–9.
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  - Steinberg BA, Kim S, Fonarow GC, Thomas L, Ansell J, Kowey PR, et al. Drivers of hospitalization for patients with atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). Am Heart J. 2014 May;167(5):735-42.e2.
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  - Huffman KM, Sun J-L, Thomas L, Bales CW, Califf RM, Yates T, et al. Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: results from NAVIGATOR. Metabolism. 2014 Apr;63(4):554–61.
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  - Yates T, Haffner SM, Schulte PJ, Thomas L, Huffman KM, Bales CW, et al. Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis. Lancet. 2014 Mar 22;383(9922):1059–66.
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  - Harskamp RE, Wang TY, Bhatt DL, Wiviott SD, Amsterdam EA, Li S, et al. Hospital patterns of medical management strategy use for patients with non-ST-elevation myocardial infarction and 3-vessel or left main coronary artery disease. Am Heart J. 2014 Mar;167(3):355-362.e3.
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  - Xian Y, Chen AY, Thomas L, Roe MT, Subherwal S, Cannon CP, et al. Sources of hospital-level variation in major bleeding among patients with non-st-segment elevation myocardial infarction: a report from the National Cardiovascular Data Registry (NCDR). Circ Cardiovasc Qual Outcomes. 2014 Mar;7(2):236–43.
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  - Wallentin L, Lopes RD, Hanna M, Thomas L, Hellkamp A, Nepal S, et al. Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation". Circulation. 2014 Jan 14;129(2):e21–2.
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  - Alexander JH, Lopes RD, Thomas L, Alings M, Atar D, Aylward P, et al. Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial. Eur Heart J. 2014 Jan;35(4):224–32.
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  - Harskamp RE, Wang TY, Bhatt DL, Wiviott SD, Amsterdam EA, Li S, et al. Hospital patterns of medical management strategy use for patients with non-ST-elevation myocardial infarction and 3-vessel or left main coronary artery disease. American Heart Journal. 2014;167(3):355-362.e3.
  - Shen L, Shah BR, Reyes EM, Thomas L, Wojdyla D, Diem P, et al. Role of diuretics, β blockers, and statins in increasing the risk of diabetes in patients with impaired glucose tolerance: reanalysis of data from the NAVIGATOR study. Bmj. 2013 Dec 9;347:f6745.
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  - Shen L, Peterson ED, Li S, Thomas L, Alexander K, Xian Y, et al. The association between smoking and long-term outcomes after non-ST-segment elevation myocardial infarction in older patients. Am Heart J. 2013 Dec;166(6):1056–62.
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  - Steinberg BA, Holmes DN, Piccini JP, Ansell J, Chang P, Fonarow GC, et al. Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation. J Am Heart Assoc. 2013 Nov 25;2(6):e000535.
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  - Fosbol EL, Wang TY, Li S, Piccini J, Lopes RD, Mills RM, et al. Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy. Am Heart J. 2013 Nov;166(5):864–70.
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  - Latini R, Staszewsky L, Sun J-L, Bethel MA, Disertori M, Haffner SM, et al. Incidence of atrial fibrillation in a population with impaired glucose tolerance: the contribution of glucose metabolism and other risk factors. A post hoc analysis of the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial. Am Heart J. 2013 Nov;166(5):935-40.e1.
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  - Shah BR, Thomas KL, Elliot-Bynum S, Thomas K, Damon K, Allen LaPointe N, et al. Check it, change it: a community-based intervention to improve blood pressure control. Circ Cardiovasc Qual Outcomes. 2013 Nov;6(6):741–8.
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  - Thomas L, Stefanski LA, Davidian M. Moment Adjusted Imputation for Multivariate Measurement Error Data with Applications to Logistic Regression. Comput Stat Data Anal. 2013 Nov 1;67:15–24.
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  - Hess CN, Shah BR, Peng SA, Thomas L, Roe MT, Peterson ED. Association of early physician follow-up and 30-day readmission after non-ST-segment-elevation myocardial infarction among older patients. Circulation. 2013 Sep 10;128(11):1206–13.
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  - Garcia DA, Wallentin L, Lopes RD, Thomas L, Alexander JH, Hylek EM, et al. Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial. Am Heart J. 2013 Sep;166(3):549–58.
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  - Preiss D, Giles TD, Thomas LE, Sun J-L, Haffner SM, Holman RR, et al. Predictors of stroke in patients with impaired glucose tolerance: results from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial. Stroke. 2013 Sep;44(9):2590–3.
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  - Steinberg BA, Kim S, Piccini JP, Fonarow GC, Lopes RD, Thomas L, et al. Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry. Circulation. 2013 Aug 13;128(7):721–8.
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  - Al-Khatib SM, Thomas L, Wallentin L, Lopes RD, Gersh B, Garcia D, et al. Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial. Eur Heart J. 2013 Aug;34(31):2464–71.
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  - Bagai A, Chen AY, Wang TY, Alexander KP, Thomas L, Ohman EM, et al. Long-term outcomes among older patients with non-ST-segment elevation myocardial infarction complicated by cardiogenic shock. Am Heart J. 2013 Aug;166(2):298–305.
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  - Fosbol EL, Holmes DN, Piccini JP, Thomas L, Reiffel JA, Mills RM, et al. Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry. J Am Heart Assoc. 2013 Jul 18;2(4):e000110.
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  - Bethel MA, Chacra AR, Deedwania P, Fulcher GR, Holman RR, Jenssen T, et al. A novel risk classification paradigm for patients with impaired glucose tolerance and high cardiovascular risk. Am J Cardiol. 2013 Jul 15;112(2):231–7.
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  - Cullen MW, Kim S, Piccini JP, Ansell JE, Fonarow GC, Hylek EM, et al. Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. Circ Cardiovasc Qual Outcomes. 2013 Jul;6(4):461–9.
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  - Hess PL, Kim S, Piccini JP, Allen LA, Ansell JE, Chang P, et al. Use of evidence-based cardiac prevention therapy among outpatients with atrial fibrillation. Am J Med. 2013 Jul;126(7):625-32.e1.
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  - Wallentin L, Lopes RD, Hanna M, Thomas L, Hellkamp A, Nepal S, et al. Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation. Circulation. 2013 Jun 4;127(22):2166–76.
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  - Chatterjee R, Thomas L, Svetkey L, Brancati FL, Califf RM, Edelman D. Effects of changes in potassium with valsartan use on diabetes risk: Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial. Am J Hypertens. 2013 Jun;26(6):723–6.
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  - Roe MT, Li S, Thomas L, Wang TY, Alexander KP, Ohman EM, et al. Long-term outcomes after invasive management for older patients with non-ST-segment elevation myocardial infarction. Circ Cardiovasc Qual Outcomes. 2013 May 1;6(3):323–32.
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  - Manfredi JA, Al-Khatib SM, Shaw LK, Thomas L, Fogel RI, Padanilam B, et al. Association between left ventricular ejection fraction post-cardiac resynchronization treatment and subsequent implantable cardioverter defibrillator therapy for sustained ventricular tachyarrhythmias. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):257–64.
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  - Fosbøl EL, Peterson ED, Weeke P, Wang TY, Mathews R, Kober L, et al. Spousal depression, anxiety, and suicide after myocardial infarction. Eur Heart J. 2013 Mar;34(9):649–56.
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  - Wong YW, Thomas L, Sun J-L, McMurray JJV, Krum H, Hernandez AF, et al. Predictors of incident heart failure hospitalizations among patients with impaired glucose tolerance: insight from the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research study. Circ Heart Fail. 2013 Mar;6(2):203–10.
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  - Thomas L, Peterson ED. Statistical analysis plans in observational research--reply. Jama. 2013 Jan 2;309(1):32.
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  - Leonardi S, Thomas L, Neely ML, Tricoci P, Lopes RD, White HD, et al. Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction. J Am Coll Cardiol. 2012 Dec 4;60(22):2296–304.
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  - Hohnloser SH, Hijazi Z, Thomas L, Alexander JH, Amerena J, Hanna M, et al. Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial. Eur Heart J. 2012 Nov;33(22):2821–30.
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  - Thomas L, Peterson ED. The value of statistical analysis plans in observational research: defining high-quality research from the start. Jama. 2012 Aug 22;308(8):773–4.
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  - Lopes RD, Subherwal S, Holmes DN, Thomas L, Wang TY, Rao SV, et al. The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction. Eur Heart J. 2012 Aug;33(16):2044–53.
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  - Subherwal S, Bhatt DL, Li S, Wang TY, Thomas L, Alexander KP, et al. Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction. Circ Cardiovasc Qual Outcomes. 2012 Jul 1;5(4):541–9.
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  - Subherwal S, Peterson ED, Dai D, Thomas L, Messenger JC, Xian Y, et al. Temporal trends in and factors associated with bleeding complications among patients undergoing percutaneous coronary intervention: a report from the National Cardiovascular Data CathPCI Registry. J Am Coll Cardiol. 2012 May 22;59(21):1861–9.
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  - Fosbol EL, Wang TY, Li S, Piccini JP, Lopes RD, Shah B, et al. Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction. Am Heart J. 2012 Apr;163(4):720–8.
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  - Kociol RD, Lopes RD, Clare R, Thomas L, Mehta RH, Kaul P, et al. International variation in and factors associated with hospital readmission after myocardial infarction. Jama. 2012 Jan 4;307(1):66–74.
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  - Samsa GP, Thomas L, Lee LS, Neal EM. An active learning approach to teach advanced multi-predictor modeling concepts to clinicians. Journal of Statistics Education. 2012 Jan 1;20(1):1–34.
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  - Preiss D, Thomas LE, Sun J-L, Haffner SM, Holman RR, Standl E, et al. Predictors of cardiovascular events in a contemporary population with impaired glucose tolerance: an observational analysis of the Nateglinide and Valsartan in impaired glucose tolerance outcomes research (NAVIGATOR) trial. Bmj Open. 2012;2(6).
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  - Thomas L, Stefanski L, Davidian M. A moment-adjusted imputation method for measurement error models. Biometrics. 2011 Dec;67(4):1461–70.
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  - Roe MT, Chen AY, Thomas L, Wang TY, Alexander KP, Hammill BG, et al. Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk score. Am Heart J. 2011 Nov;162(5):875-883.e1.
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  - Piccini JP, Fraulo ES, Ansell JE, Fonarow GC, Gersh BJ, Go AS, et al. Outcomes registry for better informed treatment of atrial fibrillation: rationale and design of ORBIT-AF. Am Heart J. 2011 Oct;162(4):606-612.e1.
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  - Britton KA, Aggarwal V, Chen AY, Alexander KP, Amsterdam E, Fraulo E, et al. No association between hemoglobin A1c and in-hospital mortality in patients with diabetes and acute myocardial infarction. Am Heart J. 2011 Apr;161(4):657-663.e1.
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  - Fiuzat M, Shaw LK, Thomas L, Felker GM, O’Connor CM. United States stock market performance and acute myocardial infarction rates in 2008-2009 (from the Duke Databank for Cardiovascular Disease). Am J Cardiol. 2010 Dec 1;106(11):1545–9.
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  - Berger JS, Elliott L, Gallup D, Roe M, Granger CB, Armstrong PW, et al. Sex differences in mortality following acute coronary syndromes. Jama. 2009 Aug 26;302(8):874–82.
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  - Ashley-Koch AE, Elliott L, Kail ME, De Castro LM, Jonassaint J, Jackson TL, et al. Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. Blood. 2008 Jun 15;111(12):5721–6.
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  - DREAM Trial Investigators, Dagenais GR, Gerstein HC, Holman R, Budaj A, Escalante A, et al. Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabetes Care. 2008 May;31(5):1007–14.
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  - Elliott L, Ashley-Koch AE, De Castro L, Jonassaint J, Price J, Ataga KI, et al. Genetic polymorphisms associated with priapism in sickle cell disease. Br J Haematol. 2007 May;137(3):262–7.
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  - DREAM Trial Investigators, Bosch J, Yusuf S, Gerstein HC, Pogue J, Sheridan P, et al. Effect of ramipril on the incidence of diabetes. N Engl J Med. 2006 Oct 12;355(15):1551–62.
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- Conference Papers
  - Thomas M, Khariton Y, Fonarow GC, Arnold SV, Hill L, Nassif ME, et al. Association between sacubitril/valsartan initiation and real-world health status trajectories over 18 months in heart failure with reduced ejection fraction. In: Esc Heart Failure. 2021. p. 2670–8.
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  - Melloni C, Dunning A, Granger CB, Thomas L, Khouri MG, Garcia DA, et al. Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial. In: Am J Med. 2017. p. 1440-1448.e1.
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  - Piccini J, Washam JB, Simon DN, Thomas LE, Hylek EM, Fonarow GC, et al. Pharmacotherapy for atrial fibrillation in patients with chronic kidney disease: insights from the outcomes registry for better informed treatment of atrial fibrillation (ORBIT AF). In: European Heart Journal. OXFORD UNIV PRESS; 2016. p. 685–685.
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  - Pokorney SD, Simon DN, Thomas LE, Fonarow GC, Mahaffey KW, Gersh BJ, et al. Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT AF). In: European Heart Journal. OXFORD UNIV PRESS; 2016. p. 686–686.
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  - Noheria A, Shrader P, Piccini JP, Fonarow GC, Kowey PR, Mahaffey KW, et al. Rhythm Control Versus Rate Control and Clinical Outcomes in Patients With Atrial Fibrillation: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). In: Circulation. LIPPINCOTT WILLIAMS & WILKINS; 2015.
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  - Durheim MT, Cyr DD, Al-Khatib SM, Thomas LE, Lopes RD, Gersh BJ, et al. Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial. In: American Journal of Respiratory and Critical Care Medicine. AMER THORACIC SOC; 2015.
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Teaching & Mentoring
Recent Courses
- BIOSTAT 709: Observational Studies 2023
- BIOSTAT 709: Observational Studies 2021

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