Laine Elliott Thomas | Scholars@Duke

Laine Elliott Thomas
Associate Professor of Biostatistics and Bioinformatics

Measurement error, longitudinal data, joint modeling

Current Appointments & Affiliations

Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2018
Associate Director, DCRI Biostatistics, Biostatistics & Bioinformatics, Basic Science Departments 2018
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2009

Contact Information

2400 Pratt Street, 6002 North Pavilion, Durham, NC 27705
Duke Box 3850, Durham, NC 27710
laine.thomas@duke.edu (919) 684-1289

Background
Education, Training, & Certifications
- Ph.D., North Carolina State University 2009
Duke Appointment History
- Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2009 - 2018
Leadership & Clinical Positions at Duke
- Associate Director, Biostatistics at the DCRI
Expertise
Global Scholarship
- Research
  - Denmark (Country)
Research
Selected Grants
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2003 - 2024
- CHAMP-HF awarded by Novartis Pharmaceuticals Corporation 2016 - 2020
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- Statistical Methods for Complex Data in Cardiovascular Disease awarded by North Carolina State University 2013 - 2018
- Matching Methods for Comparative Effectiveness Studies of Longitudinal Treatments awarded by Agency for Healthcare Research and Quality 2015 - 2017
- NCDR-ACTION awarded by American College of Cardiology Foundation 2008 - 2015
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Jackson, LR, Kim, S, Shrader, P, Blanco, R, Thomas, L, Ezekowitz, MD, Ansell, J, Fonarow, GC, Gersh, BJ, Go, AS, Kowey, PR, Mahaffey, KW, Hylek, EM, Peterson, ED, and Piccini, JP. "Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry." Journal of Thrombosis and Thrombolysis 46, no. 4 (November 2018): 435-439. Full Text
  - O'Brien, EC, Li, S, Thomas, L, Wang, TY, Roe, MT, and Peterson, ED. "The impact of clinical vs administrative claims coding on hospital risk-adjusted outcomes." Clinical Cardiology 41, no. 9 (September 22, 2018): 1225-1231. Full Text
  - DeVore, AD, Hill, CL, Thomas, L, Sharma, PP, Albert, NM, Butler, J, Patterson, JH, Spertus, JA, Williams, FB, Duffy, CI, McCague, K, Hernandez, AF, and Fonarow, GC. "Patient, Provider, and Practice Characteristics Associated With Sacubitril/Valsartan Use in the United States." Circulation. Heart Failure 11, no. 9 (September 2018): e005400-null. Full Text
  - Rymer, JA, Chen, AY, Thomas, L, Stafford, J, Enriquez, JR, Goyal, A, Peterson, ED, and Wang, TY. "Advanced Practice Provider Versus Physician-Only Outpatient Follow-Up After Acute Myocardial Infarction." Journal of the American Heart Association 7, no. 17 (September 2018): e008481-null. Full Text
  - Washam, JB, Holmes, DN, Thomas, LE, Pokorney, SD, Hylek, EM, Fonarow, GC, Mahaffey, KW, Gersh, BJ, Kowey, PR, Ansell, JE, Go, AS, Reiffel, JA, Freeman, JV, Singer, DE, Naccarelli, G, Blanco, R, Peterson, ED, and Piccini, JP. "Pharmacotherapy for Atrial Fibrillation in Patients With Chronic Kidney Disease: Insights From ORBIT-AF." Journal of the American Heart Association 7, no. 18 (September 2018): e008928-null. Full Text
  - Jackson, LR, Kim, S, Fonarow, GC, Freeman, JV, Gersh, BJ, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Singer, D, Thomas, L, Blanco, R, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation Patients and Investigators, . "Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHA2DS2-VASc Scores: Findings From the ORBIT-AF I and II Registries." Journal of the American Heart Association 7, no. 16 (August 2018): e008764-null. Full Text Open Access Copy
  - Greene, SJ, Butler, J, Albert, NM, DeVore, AD, Sharma, PP, Duffy, CI, Hill, CL, McCague, K, Mi, X, Patterson, JH, Spertus, JA, Thomas, L, Williams, FB, Hernandez, AF, and Fonarow, GC. "Medical Therapy for Heart Failure With Reduced Ejection Fraction: The CHAMP-HF Registry." Journal of the American College of Cardiology 72, no. 4 (July 2018): 351-366. Full Text
  - Stewart, EA, Lytle, BL, Thomas, L, Wegienka, GR, Jacoby, V, Diamond, MP, Nicholson, WK, Anchan, RM, Venable, S, Wallace, K, Marsh, EE, Maxwell, GL, Borah, BJ, Catherino, WH, and Myers, ER. "The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design." American Journal of Obstetrics and Gynecology 219, no. 1 (July 2018): 95.e1-95.e10. Full Text
  - DeVore, AD, Mi, X, Thomas, L, Sharma, PP, Albert, NM, Butler, J, Hernandez, AF, Patterson, JH, Spertus, JA, Williams, FB, Duffy, CI, McCague, K, and Fonarow, GC. "Characteristics and Treatments of Patients Enrolled in the CHAMP-HF Registry Compared With Patients Enrolled in the PARADIGM-HF Trial." Journal of the American Heart Association 7, no. 12 (June 12, 2018). Full Text
  - O'Brien, EC, Holmes, DN, Thomas, L, Fonarow, GC, Kowey, PR, Ansell, JE, Mahaffey, KW, Gersh, BJ, Peterson, ED, Piccini, JP, and Hylek, EM. "Therapeutic Strategies Following Major, Clinically Relevant Nonmajor, and Nuisance Bleeding in Atrial Fibrillation: Findings From ORBIT-AF." Journal of the American Heart Association 7, no. 12 (June 9, 2018). Full Text
  - Khariton, Y, Nassif, ME, Thomas, L, Fonarow, GC, Mi, X, DeVore, AD, Duffy, C, Sharma, PP, Albert, NM, Patterson, JH, Butler, J, Hernandez, AF, Williams, FB, McCague, K, and Spertus, JA. "Health Status Disparities by Sex, Race/Ethnicity, and Socioeconomic Status in Outpatients With Heart Failure." Jacc. Heart Failure 6, no. 6 (June 2018): 465-473. Full Text
  - Udell, JA, Desai, NR, Li, S, Thomas, L, de Lemos, JA, Wright-Slaughter, P, Zhang, W, Roe, MT, and Bhatt, DL. "Neighborhood Socioeconomic Disadvantage and Care After Myocardial Infarction in the National Cardiovascular Data Registry." Circulation. Cardiovascular Quality and Outcomes 11, no. 6 (June 2018): e004054-null. Full Text
  - Fanaroff, AC, Chen, AY, Thomas, LE, Pieper, KS, Garratt, KN, Peterson, ED, Newby, LK, de Lemos, JA, Kosiborod, MN, Amsterdam, EA, and Wang, TY. "Risk Score to Predict Need for Intensive Care in Initially Hemodynamically Stable Adults With Non-ST-Segment-Elevation Myocardial Infarction." Journal of the American Heart Association 7, no. 11 (May 25, 2018). Full Text
  - O'Brien, EC, Holmes, DN, Thomas, LE, Fonarow, GC, Allen, LA, Gersh, BJ, Kowey, PR, Singer, DE, Ezekowitz, MD, Naccarelli, GV, Ansell, JE, Chan, PS, Mahaffey, KW, Go, AS, Freeman, JV, Reiffel, JA, Peterson, ED, Piccini, JP, and Hylek, EM. "Prognostic Significance of Nuisance Bleeding in Anticoagulated Patients with Atrial Fibrillation." Circulation (April 20, 2018). Full Text
  - Fudim, M, Liu, PR, Shrader, P, Blanco, RG, Allen, LA, Fonarow, GC, Gersh, BJ, Kowey, PR, Mahaffey, KW, Hylek, E, Go, AS, Thomas, L, Peterson, ED, and Piccini, JP. "Mineralocorticoid Receptor Antagonism in Patients With Atrial Fibrillation: Findings From the ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) Registry." Journal of the American Heart Association 7, no. 8 (April 13, 2018). Full Text
  - Khariton, Y, Hernandez, AF, Fonarow, GC, Sharma, PP, Duffy, CI, Thomas, L, Mi, X, Albert, NM, Butler, J, McCague, K, Nassif, ME, Williams, FB, DeVore, A, Patterson, JH, and Spertus, JA. "Health Status Variation Across Practices in Outpatients With Heart Failure: Insights From the CHAMP-HF (Change the Management of Patients With Heart Failure) Registry." Circulation. Cardiovascular Quality and Outcomes 11, no. 4 (April 2018): e004668-null. Full Text
  - Pokorney, SD, Yen, DC, Campbell, KB, Allen LaPointe, NM, Sheng, S, Thomas, L, Bahnson, TD, Daubert, JP, Picini, JP, Jackson, KP, Thomas, KL, and Al-Khatib, SM. "Dofetilide dose reductions and discontinuations in women compared with men." Heart Rhythm 15, no. 4 (April 2018): 478-484. Full Text
  - Lopes, RD, Rordorf, R, De Ferrari, GM, Leonardi, S, Thomas, L, Wojdyla, DM, Ridefelt, P, Lawrence, JH, De Caterina, R, Vinereanu, D, Hanna, M, Flaker, G, Al-Khatib, SM, Hohnloser, SH, Alexander, JH, Granger, CB, Wallentin, L, and ARISTOTLE Committees and Investigators, . "Digoxin and Mortality in Patients With Atrial Fibrillation." Journal of the American College of Cardiology 71, no. 10 (March 2018): 1063-1074. Full Text
  - Shavadia, JS, French, W, Hellkamp, AS, Thomas, L, Bates, ER, Manoukian, SV, Kontos, MC, Suter, R, Henry, TD, Dauerman, HL, Roe, MT, and AHA Mission: Lifeline® Investigators, . "Comprehensive electrocardiogram-to-device time for primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A report from the American Heart Association mission: Lifeline program." American Heart Journal 197 (March 2018): 9-17. Full Text
  - Steinberg, BA, Shrader, P, Pieper, K, Thomas, L, Allen, LA, Ansell, J, Chan, PS, Ezekowitz, MD, Fonarow, GC, Freeman, JV, Gersh, BJ, Kowey, PR, Mahaffey, KW, Naccarelli, GV, Reiffel, JA, Singer, DE, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT‐AF) II Investigators, . "Frequency and Outcomes of Reduced Dose Non-Vitamin K Antagonist Anticoagulants: Results From ORBIT-AF II (The Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II)." Journal of the American Heart Association 7, no. 4 (February 16, 2018). Full Text
  - Echouffo-Tcheugui, JB, Shrader, P, Thomas, L, Piccini, JP, and Fonarow, GC. "Reply: Graphing Ratio Measures on Forest Plot." Journal of the American College of Cardiology 71, no. 5 (February 2018): 586-. (Letter) Full Text
  - Wang, WT, Hellkamp, A, Doll, JA, Thomas, L, Navar, AM, Fonarow, GC, Julien, HM, Peterson, ED, and Wang, TY. "Lipid Testing and Statin Dosing After Acute Myocardial Infarction." Journal of the American Heart Association 7, no. 3 (January 25, 2018). Full Text
  - Inohara, T, Shrader, P, Pieper, K, Blanco, RG, Thomas, L, Singer, DE, Freeman, JV, Allen, LA, Fonarow, GC, Gersh, B, Ezekowitz, MD, Kowey, PR, Reiffel, JA, Naccarelli, GV, Chan, PS, Steinberg, BA, Peterson, ED, and Piccini, JP. "Association of of Atrial Fibrillation Clinical Phenotypes With Treatment Patterns and Outcomes: A Multicenter Registry Study." Jama Cardiology 3, no. 1 (January 2018): 54-63. Full Text
  - Kraus, WE, Yates, T, Tuomilehto, J, Sun, J-L, Thomas, L, McMurray, JJV, Bethel, MA, and Holman, RR. "Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial." Bmj Open Diabetes Research & Care 6, no. 1 (January 2018): e000523-null. Full Text
  - Thomas, LE, and Schulte, PJ. "Separating variability in healthcare practice patterns from random error." Statistical Methods in Medical Research (January 2018): 962280217754230-null. Full Text
  - Steinberg, BA, Gao, H, Shrader, P, Pieper, K, Thomas, L, Camm, AJ, Ezekowitz, MD, Fonarow, GC, Gersh, BJ, Goldhaber, S, Haas, S, Hacke, W, Kowey, PR, Ansell, J, Mahaffey, KW, Naccarelli, G, Reiffel, JA, Turpie, A, Verheugt, F, Piccini, JP, Kakkar, A, Peterson, ED, Fox, KAA, GARFIELD-AF, , and ORBIT-AF Investigators, . "International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries." American Heart Journal 194 (December 2017): 132-140. Full Text
  - Barnett, AS, Kim, S, Fonarow, GC, Thomas, LE, Reiffel, JA, Allen, LA, Freeman, JV, Naccarelli, G, Mahaffey, KW, Go, AS, Kowey, PR, Ansell, JE, Gersh, BJ, Hylek, EM, Peterson, ED, and Piccini, JP. "Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines: Findings From ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation)." Circulation. Arrhythmia and Electrophysiology 10, no. 11 (November 2017). Full Text
  - Xian, Y, Thomas, L, Liang, L, Federspiel, JJ, Webb, LE, Bushnell, CD, Duncan, PW, Schwamm, LH, Stein, J, Fonarow, GC, Hoenig, H, Montalvo, C, George, MG, Lutz, BJ, Peterson, ED, and Bettger, JP. "Unexplained Variation for Hospitals' Use of Inpatient Rehabilitation and Skilled Nursing Facilities After an Acute Ischemic Stroke." Stroke 48, no. 10 (October 2017): 2836-2842. Full Text
  - Echouffo-Tcheugui, JB, Shrader, P, Thomas, L, Gersh, BJ, Kowey, PR, Mahaffey, KW, Singer, DE, Hylek, EM, Go, AS, Peterson, ED, Piccini, JP, and Fonarow, GC. "Care Patterns and Outcomes in Atrial Fibrillation Patients With and Without Diabetes: ORBIT-AF Registry." Journal of the American College of Cardiology 70, no. 11 (September 2017): 1325-1335. Full Text
  - Pagidipati, NJ, Hellkamp, A, Thomas, L, Gulati, M, Peterson, ED, and Wang, TY. "Use of Prescription Smoking Cessation Medications After Myocardial Infarction Among Older Patients in Community Practice." Jama Cardiology 2, no. 9 (September 2017): 1040-1042. Full Text
  - Brennan, JM, Thomas, L, Cohen, DJ, Shahian, D, Wang, A, Mack, MJ, Holmes, DR, Edwards, FH, Frankel, NZ, Baron, SJ, Carroll, J, Thourani, V, Tuzcu, EM, Arnold, SV, Cohn, R, Maser, T, Schawe, B, Strong, S, Stickfort, A, Patrick-Lake, E, Graham, FL, Dai, D, Li, F, Matsouaka, RA, O'Brien, S, Pencina, MJ, and Peterson, ED. "Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison." Journal of the American College of Cardiology 70, no. 4 (July 2017): 439-450. Full Text
  - DeVore, AD, Thomas, L, Albert, NM, Butler, J, Hernandez, AF, Patterson, JH, Spertus, JA, Williams, FB, Turner, SJ, Chan, WW, Duffy, CI, McCague, K, Mi, X, and Fonarow, GC. "Change the management of patients with heart failure: Rationale and design of the CHAMP-HF registry." American heart journal 189 (July 2017): 177-183. Full Text
  - Melloni, C, Shrader, P, Carver, J, Piccini, JP, Thomas, L, Fonarow, GC, Ansell, J, Gersh, B, Go, AS, Hylek, E, Herling, IM, Mahaffey, KW, Yu, AF, Peterson, ED, Kowey, PR, and ORBIT-AF Steering Committee, . "Management and outcomes of patients with atrial fibrillation and a history of cancer: the ORBIT-AF registry." European Heart Journal. Quality of Care & Clinical Outcomes 3, no. 3 (July 2017): 192-197. Full Text Open Access Copy
  - Steinberg, BA, Shrader, P, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Hylek, E, Kowey, PR, Mahaffey, KW, O'Brien, EC, Singer, DE, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators and Patients, . "Factors associated with non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)." American Heart Journal 189 (July 2017): 40-47. Full Text
  - Cherian, TS, Shrader, P, Fonarow, GC, Allen, LA, Piccini, JP, Peterson, ED, Thomas, L, Kowey, PR, Gersh, BJ, and Mahaffey, KW. "Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF])." The American Journal of Cardiology 119, no. 11 (June 2017): 1763-1769. Full Text
  - Lopes, RD, Guimarães, PO, Kolls, BJ, Wojdyla, DM, Bushnell, CD, Hanna, M, Easton, JD, Thomas, L, Wallentin, L, Al-Khatib, SM, Held, C, Gabriel Melo de Barros E Silva, P, Alexander, JH, Granger, CB, and Diener, H-C. "Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy." Blood 129, no. 22 (June 2017): 2980-2987. Full Text
  - Bethel, MA, Hyland, KA, Chacra, AR, Deedwania, P, Fulcher, GR, Holman, RR, Jenssen, T, Levitt, NS, McMurray, JJV, Boutati, E, Thomas, L, Sun, J-L, Haffner, SM, and NAVIGATOR Study Group, . "Updated risk factors should be used to predict development of diabetes." Journal of diabetes and its complications 31, no. 5 (May 2017): 859-863. Full Text
  - Steinberg, BA, Simon, DN, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Kowey, PR, Mahaffey, KW, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators and Patients, . "Management of Major Bleeding in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants Compared With Warfarin in Clinical Practice (from Phase II of the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF II])." The American Journal of Cardiology 119, no. 10 (May 2017): 1590-1595. Full Text
  - Hess, PL, Kim, S, Fonarow, GC, Thomas, L, Singer, DE, Freeman, JV, Gersh, BJ, Ansell, J, Kowey, PR, Mahaffey, KW, Chan, PS, Steinberg, BA, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Patients and Investigators, . "Absence of Oral Anticoagulation and Subsequent Outcomes Among Outpatients with Atrial Fibrillation." The American Journal of Medicine 130, no. 4 (April 2017): 449-456. Full Text
  - Sharma, A, de Souza Brito, F, Sun, J-L, Thomas, L, Haffner, S, Holman, RR, and Lopes, RD. "Noncardiovascular deaths are more common than cardiovascular deaths in patients with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: Insights from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial." American Heart Journal 186 (April 2017): 73-82. Full Text
  - Pokorney, SD, Kim, S, Thomas, L, Fonarow, GC, Kowey, PR, Gersh, BJ, Mahaffey, KW, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators, . "Cardioversion and subsequent quality of life and natural history of atrial fibrillation." American Heart Journal 185 (March 2017): 59-66. Full Text
  - Westenbrink, BD, Alings, M, Granger, CB, Alexander, JH, Lopes, RD, Hylek, EM, Thomas, L, Wojdyla, DM, Hanna, M, Keltai, M, Steg, PG, De Caterina, R, Wallentin, L, and van Gilst, WH. "Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." American Heart Journal 185 (March 2017): 140-149. Full Text
  - Hu, PT, Lopes, RD, Stevens, SR, Wallentin, L, Thomas, L, Alexander, JH, Hanna, M, Lewis, BS, Verheugt, FWA, Granger, CB, and Jones, WS. "Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial." Journal of the American Heart Association 6, no. 1 (January 17, 2017). Full Text
  - Bettger, JP, Thomas, L, Liang, L, Xian, Y, Bushnell, CD, Saver, JL, Fonarow, GC, and Peterson, ED. "Hospital Variation in Functional Recovery After Stroke." Circulation. Cardiovascular Quality and Outcomes 10, no. 1 (January 2017). Full Text
  - Fanaroff, AC, Peterson, ED, Chen, AY, Thomas, L, Doll, JA, Fordyce, CB, Newby, LK, Amsterdam, EA, Kosiborod, MN, de Lemos, JA, and Wang, TY. "Intensive Care Unit Utilization and Mortality Among Medicare Patients Hospitalized With Non-ST-Segment Elevation Myocardial Infarction." Jama Cardiology 2, no. 1 (January 2017): 36-44. Full Text
  - Guimarães, PO, Wojdyla, DM, Alexander, JH, Thomas, L, Alings, M, Flaker, GC, Al-Khatib, SM, Hanna, M, Horowitz, JD, Wallentin, L, Granger, CB, and Lopes, RD. "Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial." International Journal of Cardiology 227 (January 2017): 443-449. Full Text
  - Pokorney, SD, Miller, AL, Chen, AY, Thomas, L, Fonarow, GC, de Lemos, JA, Al-Khatib, SM, Velazquez, EJ, Peterson, ED, and Wang, TY. "Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction." Circulation 135, no. 1 (January 2017): 38-47. Full Text
  - Randolph, TC, Simon, DN, Thomas, L, Allen, LA, Fonarow, GC, Gersh, BJ, Kowey, PR, Reiffel, JA, Naccarelli, GV, Chan, PS, Spertus, JA, Peterson, ED, Piccini, JP, and ORBIT AF Investigators and Patients, . "Patient factors associated with quality of life in atrial fibrillation." American Heart Journal 182 (December 2016): 135-143. Full Text
  - Steinberg, BA, Shrader, P, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Kowey, PR, Mahaffey, KW, Naccarelli, G, Reiffel, J, Singer, DE, Peterson, ED, Piccini, JP, and ORBIT-AF Investigators and Patients, . "Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry." Journal of the American College of Cardiology 68, no. 24 (December 2016): 2597-2604. Full Text
  - Thomas, LE, and Pencina, MJ. "Do Not Over (P) Value Your Research Article." JAMA cardiology 1, no. 9 (December 2016): 1055-. Full Text
  - Pandey, A, Kim, S, Moore, C, Thomas, L, Gersh, B, Allen, LA, Kowey, PR, Mahaffey, KW, Hylek, E, Peterson, ED, Piccini, JP, and Fonarow, GC. "Predictors and Prognostic Implications of Incident Heart Failure in Patients With Prevalent Atrial Fibrillation." Jacc. Heart Failure (November 30, 2016). Full Text
  - Steinberg, BA, Shrader, P, Kim, S, Thomas, L, Fonarow, GC, Ansell, J, Kowey, PR, Singer, DE, Gersh, BJ, Mahaffey, KW, Peterson, ED, Piccini, JP, and ORBIT-AF Investigators and Patients, . "How well does physician risk assessment predict stroke and bleeding in atrial fibrillation? Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)." American Heart Journal 181 (November 2016): 145-152. Full Text
  - Edmund Anstey, D, Li, S, Thomas, L, Wang, TY, and Wiviott, SD. "Race and Sex Differences in Management and Outcomes of Patients After ST-Elevation and Non-ST-Elevation Myocardial Infarct: Results From the NCDR." Clinical cardiology 39, no. 10 (October 2016): 585-595. Full Text
  - Kontos, MC, Wang, TY, Chen, AY, Bates, ER, Dauerman, HL, Henry, TD, Manoukian, SV, Roe, MT, Suter, R, Thomas, L, and French, WJ. "The effect of high-risk ST elevation myocardial infarction transfer patients on risk-adjusted in-hospital mortality: A report from the American Heart Association Mission: Lifeline program." American Heart Journal 180 (October 2016): 74-81. Full Text
  - Pokorney, SD, Shrader, P, Thomas, L, Fonarow, GC, Kowey, PR, Singer, DE, Ansell, J, Gersh, BJ, Mahaffey, KW, Hylek, EM, Go, AS, Piccini, JP, Peterson, ED, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators, . "Influence of Kidney Function Estimation Methods on Eligibility for Edoxaban Population Impact of the US Food and Drug Administration's Approach for Its Product Labeling." Circulation 134, no. 15 (October 2016): 1122-1124. (Letter) Full Text
  - Vora, AN, Wang, TY, Hellkamp, AS, Thomas, L, Henry, TD, Goyal, A, and Roe, MT. "Differences in Short- and Long-Term Outcomes Among Older Patients With ST-Elevation Versus Non-ST-Elevation Myocardial Infarction With Angiographically Proven Coronary Artery Disease." Circulation. Cardiovascular Quality and Outcomes 9, no. 5 (September 6, 2016): 513-522. Full Text
  - Pokorney, SD, Simon, DN, Thomas, L, Gersh, BJ, Hylek, EM, Piccini, JP, and Peterson, ED. "Stability of International Normalized Ratios in Patients Taking Long-term Warfarin Therapy." Jama 316, no. 6 (August 2016): 661-663. Full Text
  - Sutton, NR, Li, S, Thomas, L, Wang, TY, de Lemos, JA, Enriquez, JR, Shah, RU, and Fonarow, GC. "The association of left ventricular ejection fraction with clinical outcomes after myocardial infarction: Findings from the Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry-Get With the Guidelines (GWTG) Medicare-linked database." American Heart Journal 178 (August 2016): 65-73. Full Text
  - Goldstein, BA, Thomas, L, Zaroff, JG, Nguyen, J, Menza, R, and Khush, KK. "Assessment of Heart Transplant Waitlist Time and Pre- and Post-transplant Failure: A Mixed Methods Approach." Epidemiology (Cambridge, Mass.) 27, no. 4 (July 2016): 469-476. Full Text
  - Jaspers Focks, J, Brouwer, MA, Wojdyla, DM, Thomas, L, Lopes, RD, Washam, JB, Lanas, F, Xavier, D, Husted, S, Wallentin, L, Alexander, JH, Granger, CB, and Verheugt, FWA. "Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial." Bmj (Clinical Research Ed.) 353 (June 15, 2016): i2868-null. Full Text
  - Lopes, RD, Rao, M, Simon, DN, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Go, AS, Hylek, EM, Kowey, P, Piccini, JP, Singer, DE, Chang, P, Peterson, ED, and Mahaffey, KW. "Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease." The American Journal of Medicine 129, no. 6 (June 2016): 592-599.e1. Full Text
  - Pandey, A, Gersh, BJ, McGuire, DK, Shrader, P, Thomas, L, Kowey, PR, Mahaffey, KW, Hylek, E, Sun, S, Burton, P, Piccini, J, Peterson, E, and Fonarow, GC. "Association of Body Mass Index With Care and Outcomes in Patients With Atrial Fibrillation: Results From the ORBIT-AF Registry." Jacc. Clinical Electrophysiology 2, no. 3 (June 2016): 355-363. Full Text
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  - Fordyce, CB, Wang, TY, Chen, AY, Thomas, L, Granger, CB, Scirica, BM, Henry, TD, Wong, GC, Ramanathan, K, Hansen, CM, Kragholm, K, Peterson, ED, and Anderson, ML. "Long-Term Post-Discharge Risks in Older Survivors of Myocardial Infarction With and Without Out-of-Hospital Cardiac Arrest." Journal of the American College of Cardiology 67, no. 17 (May 2016): 1981-1990. Full Text
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  - Anderson, ML, Nichol, G, Dai, D, Chan, PS, Thomas, L, Al-Khatib, SM, Berg, RA, Bradley, SM, Peterson, ED, and American Heart Association’s Get With the Guidelines–Resuscitation Investigators, . "Association Between Hospital Process Composite Performance and Patient Outcomes After In-Hospital Cardiac Arrest Care." Jama Cardiology 1, no. 1 (April 2016): 37-45. Full Text
  - Golwala, H, Jackson, LR, Simon, DN, Piccini, JP, Gersh, B, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Thomas, L, Fonarow, GC, Peterson, ED, Thomas, KL, and Outcomes Registry for Better Informed Treatment for Atrial Fibrillation (ORBIT-AF) Registry, . "Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: Insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry." American Heart Journal 174 (April 2016): 29-36. Full Text
  - Noheria, A, Shrader, P, Piccini, JP, Fonarow, GC, Kowey, PR, Mahaffey, KW, Naccarelli, G, Noseworthy, PA, Reiffel, JA, Steinberg, BA, Thomas, LE, Peterson, ED, Gersh, BJ, and ORBIT-AF Investigators and Patients, . "Rhythm Control Versus Rate Control and Clinical Outcomes in Patients With Atrial Fibrillation: Results From the ORBIT-AF Registry." Jacc. Clinical Electrophysiology 2, no. 2 (April 2016): 221-229. Full Text
  - Prates, PRL, Williams, JB, Mehta, RH, Stevens, SR, Thomas, L, Smith, PK, Newby, LK, Kalil, RAK, Alexander, JH, and Lopes, RD. "Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate." Brazilian Journal of Cardiovascular Surgery 31, no. 2 (April 2016): 106-114. Full Text Open Access Copy
  - Hess, CN, Hellkamp, AS, Roe, MT, Thomas, L, Scirica, BM, Peng, SA, Peterson, ED, and Wang, TY. "Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization." Journal of the American Heart Association 5, no. 3 (March 14, 2016): e002784-null. Full Text Open Access Copy
  - Fonarow, GC, Liang, L, Thomas, L, Xian, Y, Saver, JL, Smith, EE, Schwamm, LH, Peterson, ED, Hernandez, AF, Duncan, PW, O'Brien, EC, Bushnell, C, and Prvu Bettger, J. "Assessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries." Stroke 47, no. 3 (March 2016): 836-842. Full Text
  - Vora, AN, Peterson, ED, Hellkamp, AS, Sutton, NR, Panacek, E, Thomas, L, de Lemos, JA, and Wang, TY. "Care Transitions After Acute Myocardial Infarction for Transferred-In Versus Direct-Arrival Patients." Circulation. Cardiovascular Quality and Outcomes 9, no. 2 (March 2016): 109-116. Full Text
  - Jackson, LR, Kim, SH, Piccini, JP, Gersh, BJ, Naccarelli, GV, Reiffel, JA, Freeman, J, Thomas, L, Chang, P, Fonarow, GC, Go, AS, Mahaffey, KW, Peterson, ED, and Kowey, PR. "Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT-AF Registry." Clinical Cardiology 39, no. 2 (February 2016): 119-125. Full Text Open Access Copy
  - O'Brien, EC, and Thomas, LE. "Untangling the paradox: Obesity as prognostic marker in prevalent cardiovascular disease." American heart journal 172 (February 2016): 170-172. Full Text
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  - Durheim, MT, Cyr, DD, Lopes, RD, Thomas, LE, Tsuang, WM, Gersh, BJ, Held, C, Wallentin, L, Granger, CB, Palmer, SM, and Al-Khatib, SM. "Chronic obstructive pulmonary disease in patients with atrial fibrillation: Insights from the ARISTOTLE trial." International Journal of Cardiology 202 (January 2016): 589-594. Full Text
  - Xian, Y, Federspiel, JJ, Grau-Sepulveda, M, Hernandez, AF, Schwamm, LH, Bhatt, DL, Smith, EE, Reeves, MJ, Thomas, L, Webb, L, Bettger, JP, Laskowitz, DT, Fonarow, GC, and Peterson, ED. "Risks and Benefits Associated With Prestroke Antiplatelet Therapy Among Patients With Acute Ischemic Stroke Treated With Intravenous Tissue Plasminogen Activator." Jama Neurology 73, no. 1 (January 2016): 50-59. Full Text
  - O'Brien, EC, Simon, DJN, Thomas, LE, Hylek, EM, Gersh, BJ, Ansell, JE, Kowey, PR, Mahaffey, KW, Chang, P, Fonarow, GC, Pencina, MJ, Piccini, JP, and Peterson, ED. "The ORBIT bleeding score: A simple bedside score to assess bleeding risk in atrial fibrillation." European Heart Journal 36, no. 46 (December 7, 2015): 3258-3264. Full Text
  - Gruberg, L, Hellkamp, AS, Thomas, LE, de Lemos, JA, Scirica, BM, Hilliard, A, Enriquez, JR, Mohsen, A, and Wang, TY. "The Association of Previous Revascularization With In-Hospital Outcomes in Acute Myocardial Infarction Patients: Results From the National Cardiovascular Data Registry." JACC. Cardiovascular interventions 8, no. 15 (December 2015): 1954-1962. Full Text
  - O'Brien, EC, Simon, DN, Thomas, LE, Hylek, EM, Gersh, BJ, Ansell, JE, Kowey, PR, Mahaffey, KW, Chang, P, Fonarow, GC, Pencina, MJ, Piccini, JP, and Peterson, ED. "The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation." European Heart Journal 36, no. 46 (December 2015): 3258-3264. Full Text Open Access Copy
  - Rao, MP, Halvorsen, S, Wojdyla, D, Thomas, L, Alexander, JH, Hylek, EM, Hanna, M, Bahit, MC, Lopes, RD, De Caterina, R, Erol, C, Goto, S, Lanas, F, Lewis, BS, Husted, S, Gersh, BJ, Wallentin, L, Granger, CB, and Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Steering Committee and Investigators, . "Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial." Journal of the American Heart Association 4, no. 12 (December 2015). Full Text
  - Shen, L, Shah, BR, Li, S, Thomas, L, Wang, TY, Alexander, KP, Peterson, ED, He, B, and Roe, MT. "The Association of Transfer Rate From Hospitals Without Revascularization Capabilities and Mortality Risk for Older Non-ST-Segment Elevation Myocardial Infarction Patients." Clinical Cardiology 38, no. 12 (December 2015): 733-739. Full Text
  - Doll, JA, Hellkamp, A, Thomas, L, Ho, PM, Kontos, MC, Whooley, MA, Boyden, TF, Peterson, ED, and Wang, TY. "Effectiveness of cardiac rehabilitation among older patients after acute myocardial infarction." American Heart Journal 170, no. 5 (November 2015): 855-864. Full Text
  - Enriquez, JR, de Lemos, JA, Parikh, SV, Simon, DN, Thomas, LE, Wang, TY, Chan, PS, Spertus, JA, and Das, SR. "Modest Associations Between Electronic Health Record Use and Acute Myocardial Infarction Quality of Care and Outcomes: Results From the National Cardiovascular Data Registry." Circulation. Cardiovascular quality and outcomes 8, no. 6 (November 2015): 576-585. Full Text
  - Goyal, A, de Lemos, JA, Peng, SA, Thomas, L, Amsterdam, EA, Hockenberry, JM, Peterson, ED, and Wang, TY. "Association of Patient Enrollment in Medicare Part D With Outcomes After Acute Myocardial Infarction." Circulation. Cardiovascular Quality and Outcomes 8, no. 6 (November 2015): 567-575. Full Text
  - Steinberg, BA, Kim, S, Thomas, L, Fonarow, GC, Gersh, BJ, Holmqvist, F, Hylek, E, Kowey, PR, Mahaffey, KW, Naccarelli, G, Reiffel, JA, Chang, P, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT‐AF) Investigators and Patients, . "Increased Heart Rate Is Associated With Higher Mortality in Patients With Atrial Fibrillation (AF): Results From the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF)." Journal of the American Heart Association 4, no. 9 (September 14, 2015): e002031-null. Full Text Open Access Copy
  - Preiss, D, Thomas, LE, Wojdyla, DM, Haffner, SM, Gill, JMR, Yates, T, Davies, MJ, Holman, RR, McMurray, JJ, Califf, RM, Kraus, WE, and NAVIGATOR Investigators, . "Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study." Bmj Open 5, no. 8 (August 14, 2015): e007901-null. Full Text
  - Hess, CN, Peterson, ED, Peng, SA, de Lemos, JA, Fosbol, EL, Thomas, L, Bhatt, DL, Saucedo, JF, and Wang, TY. "Use and Outcomes of Triple Therapy Among Older Patients With Acute Myocardial Infarction and Atrial Fibrillation." Journal of the American College of Cardiology 66, no. 6 (August 2015): 616-627. Full Text
  - Yates, T, Davies, MJ, Haffner, SM, Schulte, PJ, Thomas, L, Huffman, KM, Bales, CW, Preiss, D, Califf, RM, Holman, RR, McMurray, JJV, Bethel, MA, Tuomilehto, J, and Kraus, WE. "Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial." Diabetic Medicine : a Journal of the British Diabetic Association 32, no. 8 (August 2015): 1090-1096. Full Text
  - Freeman, JV, Simon, DN, Go, AS, Spertus, J, Fonarow, GC, Gersh, BJ, Hylek, EM, Kowey, PR, Mahaffey, KW, Thomas, LE, Chang, P, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators and Patients, . "Association Between Atrial Fibrillation Symptoms, Quality of Life, and Patient Outcomes: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)." Circulation. Cardiovascular Quality and Outcomes 8, no. 4 (July 2015): 393-402. Full Text
  - O'Brien, EC, McCoy, LA, Thomas, L, Peterson, ED, and Wang, TY. "Patient adherence to generic versus brand statin therapy after acute myocardial infarction: Insights from the Can Rapid Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association Guidelines Registry." American Heart Journal 170, no. 1 (July 2015): 55-61. Full Text
  - Pokorney, SD, Simon, DN, Thomas, L, Fonarow, GC, Kowey, PR, Chang, P, Singer, DE, Ansell, J, Blanco, RG, Gersh, B, Mahaffey, KW, Hylek, EM, Go, AS, Piccini, JP, Peterson, ED, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators, . "Patients' time in therapeutic range on warfarin among US patients with atrial fibrillation: Results from ORBIT-AF registry." American Heart Journal 170, no. 1 (July 2015): 141-148.e1. Full Text
  - Allen, LA, Fonarow, GC, Simon, DN, Thomas, LE, Marzec, LN, Pokorney, SD, Gersh, BJ, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Chang, P, Peterson, ED, Piccini, JP, and ORBIT-AF Investigators, . "Digoxin Use and Subsequent Outcomes Among Patients in a Contemporary Atrial Fibrillation Cohort." Journal of the American College of Cardiology 65, no. 25 (June 2015): 2691-2698. Full Text
  - Holmqvist, F, Kim, S, Steinberg, BA, Reiffel, JA, Mahaffey, KW, Gersh, BJ, Fonarow, GC, Naccarelli, GV, Chang, P, Freeman, JV, Kowey, PR, Thomas, L, Peterson, ED, Piccini, JP, and ORBIT-AF Investigators, . "Heart rate is associated with progression of atrial fibrillation, independent of rhythm." Heart (British Cardiac Society) 101, no. 11 (June 2015): 894-899. Full Text Open Access Copy
  - Lopes, RD, Gharacholou, SM, Holmes, DN, Thomas, L, Wang, TY, Roe, MT, Peterson, ED, and Alexander, KP. "Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI." The American Journal of Medicine 128, no. 6 (June 2015): 582-590. Full Text
  - Pokorney, SD, Miller, AL, Chen, AY, Thomas, L, Fonarow, GC, de Lemos, JA, Al-Khatib, SM, Peterson, ED, and Wang, TY. "Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction." Jama 313, no. 24 (June 2015): 2433-2440. Full Text
  - Allen LaPointe, NM, Dai, D, Thomas, L, Piccini, JP, Peterson, ED, and Al-Khatib, SM. "Comparisons of hospitalization rates among younger atrial fibrillation patients receiving different antiarrhythmic drugs." Circulation. Cardiovascular Quality and Outcomes 8, no. 3 (May 2015): 292-300. Full Text
  - Held, C, Hylek, EM, Alexander, JH, Hanna, M, Lopes, RD, Wojdyla, DM, Thomas, L, Al-Khalidi, H, Alings, M, Xavier, D, Ansell, J, Goto, S, Ruzyllo, W, Rosenqvist, M, Verheugt, FWA, Zhu, J, Granger, CB, and Wallentin, L. "Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial." European Heart Journal 36, no. 20 (May 2015): 1264-1272. Full Text
  - Kontos, MC, Scirica, BM, Chen, AY, Thomas, L, Anderson, ML, Diercks, DB, Jollis, JG, Roe, MT, and NCDR, . "Cardiac arrest and clinical characteristics, treatments and outcomes among patients hospitalized with ST-elevation myocardial infarction in contemporary practice: A report from the National Cardiovascular Data Registry." American heart journal 169, no. 4 (April 2015): 515-22.e1. Full Text
  - Katz, M, Califf, RM, Sun, J-L, McMurray, JJV, Thomas, L, and Lopes, RD. "Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial." The American Journal of Medicine 128, no. 3 (March 2015): 297-302. Full Text
  - Allen LaPointe, NM, Dai, D, Thomas, L, Piccini, JP, Peterson, ED, and Al-Khatib, SM. "Antiarrhythmic drug use in patients <65 years with atrial fibrillation and without structural heart disease." The American Journal of Cardiology 115, no. 3 (February 2015): 316-322. Full Text
  - Allen LaPointe, NM, Dai, D, Thomas, L, Piccini, JP, Peterson, ED, and Al-Khatib, SM. "Antiarrhythmic drug use in patients <65 years with atrial fibrillation and without structural heart disease." American Journal of Cardiology 115, no. 3 (February 1, 2015): 316-322. Full Text
  - Karrowni, W, Wang, TY, Chen, AY, Thomas, L, Saucedo, JF, and El Accaoui, RN. "Chronic vitamin K antagonist therapy and bleeding risk in ST elevation myocardial infarction patients." Heart (British Cardiac Society) 101, no. 4 (February 2015): 264-270. Full Text
  - Steinberg, BA, Peterson, ED, Kim, S, Thomas, L, Gersh, BJ, Fonarow, GC, Kowey, PR, Mahaffey, KW, Sherwood, MW, Chang, P, Piccini, JP, Ansell, J, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation Investigators and Patients, . "Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)." Circulation 131, no. 5 (February 2015): 488-494. Full Text Open Access Copy
  - Vora, AN, Holmes, DN, Rokos, I, Roe, MT, Granger, CB, French, WJ, Antman, E, Henry, TD, Thomas, L, Bates, ER, and Wang, TY. "Fibrinolysis use among patients requiring interhospital transfer for ST-segment elevation myocardial infarction care: a report from the US National Cardiovascular Data Registry." Jama Internal Medicine 175, no. 2 (February 2015): 207-215. Full Text
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  - Granger, CB, Lopes, RD, Hanna, M, Ansell, J, Hylek, EM, Alexander, JH, Thomas, L, Wang, J, Bahit, MC, Verheugt, F, Lawrence, J, Xavier, D, and Wallentin, L. "Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." American heart journal 169, no. 1 (January 2015): 25-30. Full Text
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  - Holmqvist, F, Kim, S, Steinberg, BA, Reiffel, JA, Mahaffey, KW, Gersh, BJ, Fonarow, GC, Naccarelli, GV, Chang, P, Freeman, JV, Kowey, PR, Thomas, L, Peterson, ED, and Piccini, JP. "Heart rate is associated with progression of atrial fibrillation, independent of rhythm." Heart (2015). Full Text
  - Katz, M, Califf, RM, Sun, JL, McMurray, JJV, Thomas, L, and Lopes, RD. "Venous thromboembolism and cardiovascular risk: Results from the NAVIGATOR trial." American Journal of Medicine 128, no. 3 (January 1, 2015): 297-302. Full Text
  - Kontos, MC, Scirica, BM, Chen, AY, Thomas, L, Anderson, ML, Diercks, DB, Jollis, JG, and Roe, MT. "Cardiac arrest and clinical characteristics, treatments and outcomes among patients hospitalized with ST-elevation myocardial infarction in contemporary practice: A report from the National Cardiovascular Data Registry." American Heart Journal 169, no. 4 (January 1, 2015): 515-522.e1. Full Text
  - Lytle, BL, Li, S, Lofthus, DM, Thomas, L, Poteat, JL, Bhatt, DL, Cannon, CP, Fonarow, GC, Peterson, ED, Wang, TY, and Alexander, KP. "Targeted versus standard feedback: results from a randomized quality improvement trial." American Heart Journal 169, no. 1 (January 2015): 132-41.e2. Full Text
  - Garcia, D, Alexander, JH, Wallentin, L, Wojdyla, DM, Thomas, L, Hanna, M, Al-Khatib, SM, Dorian, P, Ansell, J, Commerford, P, Flaker, G, Lanas, F, Vinereanu, D, Xavier, D, Hylek, EM, Held, C, Verheugt, FWA, Granger, CB, and Lopes, RD. "Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures." Blood 124, no. 25 (December 2014): 3692-3698. Full Text
  - Preiss, D, Haffner, SM, Thomas, LE, Sun, J-L, Sattar, N, Yates, T, J Davies, M, McMurray, JJ, Holman, RR, Califf, RM, and Kraus, WE. "Change in levels of physical activity after diagnosis of type 2 diabetes: an observational analysis from the NAVIGATOR study." Diabetes, Obesity & Metabolism 16, no. 12 (December 2014): 1265-1268. Full Text
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  - Flaker, G, Lopes, RD, Hylek, E, Wojdyla, DM, Thomas, L, Al-Khatib, SM, Sullivan, RM, Hohnloser, SH, Garcia, D, Hanna, M, Amerena, J, Harjola, V-P, Dorian, P, Avezum, A, Keltai, M, Wallentin, L, Granger, CB, and ARISTOTLE Committees and Investigators, . "Amiodarone, anticoagulation, and clinical events in patients with atrial fibrillation: insights from the ARISTOTLE trial." Journal of the American College of Cardiology 64, no. 15 (October 2014): 1541-1550. Full Text
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  - de Barros e Silva, PGM, Califf, RM, Sun, J-L, McMurray, JJV, Holman, R, Haffner, S, Thomas, L, and Lopes, RD. "Chronic obstructive pulmonary disease and cardiovascular risk: insights from the NAVIGATOR trial." International Journal of Cardiology 176, no. 3 (October 2014): 1126-1128. (Letter) Full Text
  - Mathews, R, Chen, AY, Thomas, L, Wang, TY, Chin, CT, Thomas, KL, Roe, MT, and Peterson, ED. "Differences in short-term versus long-term outcomes of older black versus white patients with myocardial infarction: findings from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of American College of Cardiology/American Heart Association Guidelines (CRUSADE)." Circulation 130, no. 8 (August 2014): 659-667. Full Text
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  - DREAM Trial Investigators, , Dagenais, GR, Gerstein, HC, Holman, R, Budaj, A, Escalante, A, Hedner, T, Keltai, M, Lonn, E, McFarlane, S, McQueen, M, Teo, K, Sheridan, P, Bosch, J, Pogue, J, and Yusuf, S. "Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial." Diabetes Care 31, no. 5 (May 2008): 1007-1014. Full Text
  - Elliott, L, Ashley-Koch, AE, De Castro, L, Jonassaint, J, Price, J, Ataga, KI, Levesque, MC, Brice Weinberg, J, Eckman, JR, Orringer, EP, Vance, JM, and Telen, MJ. "Genetic polymorphisms associated with priapism in sickle cell disease." Br J Haematol 137, no. 3 (May 2007): 262-267. Full Text Link to Item
  - Bosch, J, Yusuf, S, Gerstein, HC, Pogue, J, Sheridan, P, Dagenais, G, Chiasson, JL, Diaz, R, Avezum, A, Lanas, F, Probstfield, J, Fodor, G, Holman, RR, Anand, S, Budaj, A, Conget, I, Davis, M, Dinccag, N, Enjalbert, M, Escalante, A, Hanefeld, M, Hedner, T, Jolly, K, Keltai, M, Laakso, M, Lonn, E, McQueen, M, Mohan, V, Phillips, A, Piegas, L, Pirags, V, Schmid, I, Shaw, J, Teo, K, Zimmet, P, Zinman, B, Ahuad Guerrero, R, Albisu, J, Alvarez, MS, Arregui, V, Avaca, H, Baglivo, H, Balbuena, M, Bello, F, Bono, J, Botto, M, Brandani, L, Brandes, M, Bruera, D, Cabral Venere, R, Caccavo, A, Cacurri, A, Caime, G, Capozzi, M, Carrique, A, Carrique, P, Cartasegna, L, Casabe, J, Casaccia, G, Castellanos, C, Castro, L, Cendali, G, Cerchi, P, Cerdan, M, Cinalli, M, Cipullo, M, Cismondi, M, Citta, N, Citta, L, Crespo, C, Crunger, P, Cuneo, C, De Loredo, L, De Loredo, S, Del Cerro, S, Denaro, R, Esperatti, E, Esposito, L, Farras, H, Fernandez, S, Fernandez, M, Fernandez, A, Ferrari, G, Focaccia, M, Frontini, L, Gabito, A, Gambarte, A, and Garrido, M. "Effect of ramipril on the incidence of diabetes." New England Journal of Medicine 355, no. 15 (October 12, 2006): 1551-1562. Full Text
- Conference Papers
  - Melloni, C, Dunning, A, Granger, CB, Thomas, L, Khouri, MG, Garcia, DA, Hylek, EM, Hanna, M, Wallentin, L, Gersh, BJ, Douglas, PS, Alexander, JH, and Lopes, RD. "Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial." December 2017. Full Text
  - Piccini, J, Washam, JB, Simon, DN, Thomas, LE, Hylek, EM, Fonarow, GC, Mahaffey, KW, Gersh, BJ, Kowey, PR, Ansell, JE, Go, AS, Reiffel, JA, Singer, DE, Pokorney, SD, Peterson, ED, and Investigators, ORBITAF. "Pharmacotherapy for atrial fibrillation in patients with chronic kidney disease: insights from the outcomes registry for better informed treatment of atrial fibrillation (ORBIT AF)." August 1, 2016. Link to Item
  - Pokorney, SD, Simon, DN, Thomas, LE, Fonarow, GC, Mahaffey, KW, Gersh, BJ, Kowey, PR, Singer, DE, Washam, JB, Peterson, ED, Piccini, JP, and Reiffel, JA. "Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT AF)." August 1, 2016. Link to Item
  - Noheria, A, Shrader, P, Piccini, JP, Fonarow, GC, Kowey, PR, Mahaffey, KW, Naccarelli, G, Noseworthy, PA, Reiffel, JA, Steinberg, BA, Thomas, LE, Peterson, ED, and Gersh, BJ. "Rhythm Control Versus Rate Control and Clinical Outcomes in Patients With Atrial Fibrillation: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)." Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association (AHA). Orlando, FL. November 7, 2015 - November 11, 2015.: LIPPINCOTT WILLIAMS & WILKINS, November 10, 2015. Link to Item
  - Durheim, MT, Cyr, DD, Al-Khatib, SM, Thomas, LE, Lopes, RD, Gersh, BJ, Palmer, SM, and Granger, CB. "Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial." 2015. Link to Item
Teaching & Mentoring
Recent Courses
- BIOSTAT 709: Observational Studies 2019
- BIOSTAT 904: Causal Inference 2017

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