Lalita Mazgaeen

Journal Article Blood Vessels Thrombosis and Hemostasis · November 1, 2025 Lipopolysaccharide (LPS) exposure in mice induces robust morbidity and mortality, and is widely used as a model for sepsis. However, the role of biological sex in modulating immune responses during LPS-induced sepsis remains incompletely understood. In thi ... Full text Cite

IMMU-37. PRE-TREATMENT INNATE INFLAMMATION ASSOCIATES WITH SURVIVAL AFTER POLIO VIROTHERAPY AND CAN BE MODULATED TO SENSITIZE GLIOMAS TO IN SITU VACCINATION

Conference Neuro-Oncology · November 11, 2024 AbstractEarly-stage clinical trials in glioblastoma (GBM) have tested various virotherapy strategies, yet only a subset of patients appear to benefit. We previously demonstrated that a recombinant poliovirus ... Full text Cite

CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation.

Journal Article Science advances · January 2023 Mice with SHP1 proteins, which have a single amino acid substitution from tyrosine-208 residue to asparagine (hereafter Ptpn6spin mice), develop an autoinflammatory disease with inflamed footpads. Genetic crosses to study CD47 function in ... Full text Cite

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