Scholars@Duke
Lalita Mazgaeen

Lalita Mazgaeen

Postdoctoral Associate
Neurosurgery, Neuro-Oncology

Current Appointments & Affiliations

Postdoctoral Associate Neurosurgery, Neuro-Oncology, Neurosurgery

Recent Publications

IMMU-37. PRE-TREATMENT INNATE INFLAMMATION ASSOCIATES WITH SURVIVAL AFTER POLIO VIROTHERAPY AND CAN BE MODULATED TO SENSITIZE GLIOMAS TO IN SITU VACCINATION

Conference Neuro-Oncology · November 11, 2024 AbstractEarly-stage clinical trials in glioblastoma (GBM) have tested various virotherapy strategies, yet only a subset of patients appear to benefit. We previously demonstrated that a recombinant poliovirus ... Full text Cite

CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation.

Journal Article Science advances · January 2023 Mice with SHP1 proteins, which have a single amino acid substitution from tyrosine-208 residue to asparagine (hereafter Ptpn6spin mice), develop an autoinflammatory disease with inflamed footpads. Genetic crosses to study CD47 function in ... Full text Cite

Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection.

Journal Article ImmunoHorizons · September 2020 Leishmania spp. infection is a global health problem affecting more than 2 million people every year with 300 million at risk worldwide. It is well established that a dominant Th1 response (IFN-γ, a hallmark Th1 cytokine) provides resistance, wherea ... Full text Cite
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