Lara Carine Wadi

Journal Article Epileptic Disord · December 2025 All patients with drug-resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic mat ... Full text Link to item Cite

Individualizing Programming of Responsive Neurostimulation and Deep Brain Stimulation Therapies in Epilepsy.

Journal Article J Clin Neurophysiol · July 25, 2025 Responsive neurostimulation and deep brain stimulation have emerged as effective intracranial neuromodulation therapies for drug-resistant epilepsy when surgical resection is not an option. However, programming these devices presents unique challenges in e ... Full text Link to item Cite

Sleep-related hypermotor seizures originating from the occipital lobe.

Journal Article Epileptic Disord · December 2024 We present two unique cases of sleep-related hypermotor epilepsy (SHE) originating from the occipital lobe. Patients with sleep-related seizures and drug-resistant occipital lobe epilepsy were identified from the ANPHY lab stereo-electroencephalography (SE ... Full text Link to item Cite

Early cerebral venous drainage associated with focal seizures: a correlation of digital subtraction angiography and electroencephalography. Illustrative case.

Journal Article J Neurosurg Case Lessons · April 29, 2024 BACKGROUND: Early venous drainage is a critical diagnostic feature of arteriovenous malformations (AVMs) and arteriovenous fistulas (AVFs). However, other conditions associated with early venous drainage can mimic AVMs and AVFs and mislead the treating phy ... Full text Link to item Cite

Electroconvulsive therapy for catatonia in anti-NMDA receptor encephalitis: A case series.

Journal Article J Neuroimmunol · January 15, 2024 BACKGROUND: Anti-NMDAR encephalitis is the most common cause of immune-mediated catatonia. CASE SERIES: Three females presented with neuropsychiatric symptoms and were empirically treated with first-line immunotherapy and ovarian teratoma resection for sus ... Full text Link to item Cite

Recurrent Cryptogenic Stroke in a Young Woman: Congenital Thrombotic Thrombocytopenic Purpura Unmasked

Journal Article Annals of Internal Medicine Clinical Cases · December 1, 2022 Cryptogenic stroke of undetermined cause should warrant an exhaustive neurologic and cardiovascular workup. If no cause is identified, additional investigations should be individualized on the basis of clinical history and objective findings. Herein, we pr ... Full text Open Access Cite

Magnetic Resonance Imaging Findings in High School Football Players: Brain and Cervical Spine.

Journal Article Neurotrauma Rep · 2022 Football exposes its players to traumatic brain, neck, and spinal injury. It is unknown whether the adolescent football player develops imaging abnormalities of the brain and spine that are detectable on magnetic resonance imaging (MRI). The objective of t ... Full text Link to item Cite

The Left Atrial Septal Pouch: A New Stroke Risk Factor?

Journal Article Transl Stroke Res · April 2021 The left atrial septal pouch (LASP) occurs due to incomplete fusion of septa primum and secundum at the inter-atrial septum, creating an open flap that may serve as a thromboembolic source. Prior studies have demonstrated increased prevalence of LASP in cr ... Full text Link to item Cite

Stroke Preventability in Large Vessel Occlusion Treated With Mechanical Thrombectomy.

Journal Article Front Neurol · 2021 Objective: The preventability of strokes treated by mechanical thrombectomy is unknown. The purpose of this study was to analyze stroke preventability for patients treated with mechanical thrombectomy for large vessel occlusion. Methods: We conducted retro ... Full text Link to item Cite

Mechanisms of Cerebral Microbleeds.

Journal Article J Neuropathol Exp Neurol · October 1, 2020 Cerebral microbleeds (CMB) are a common MRI finding, representing underlying cerebral microhemorrhages (CMH). The etiology of CMB and microhemorrhages is obscure. We conducted a pathological investigation of CMH, combining standard and immunohistological a ... Full text Link to item Cite

The Medial Pontine Mid-Tegmentum Syndrome.

Journal Article J Stroke Cerebrovasc Dis · June 2020 Isolated pontine infarcts are common and are often associated with well-described syndromes that are classified based on their specific clinical presentation and arterial stroke territories. Here we present a case of acute combined diplopia and unilateral ... Full text Link to item Cite

Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report.

Journal Article J Stroke Cerebrovasc Dis · April 2020 Bihemispheric ischemic strokes secondary to unilateral vessel disease are uncommon. We present the case of a 70-year-old man with multiple acute/subacute bilateral infarcts. The patient was found to have stenosis of the left internal carotid artery seconda ... Full text Link to item Cite

Bilateral Limb-Shaking Transient Ischemic Attacks.

Journal Article J Stroke Cerebrovasc Dis · March 2020 Limb shaking is a rare manifestation of transient ischemic attacks (TIA) associated with carotid occlusion, mostly unilateral events. We describe the case of a 69 year-old man who presented with repeated episodes of irregular jerking movements in the bilat ... Full text Link to item Cite

Cerebral Microbleeds in a Stroke Prevention Clinic.

Journal Article Diagnostics (Basel) · December 30, 2019 The objective of this study is to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January 2011 ... Full text Link to item Cite

Enhanced setup for wired continuous long-term EEG monitoring in juvenile and adult rats: application for epilepsy and other disorders.

Journal Article BMC Neurosci · March 4, 2019 BACKGROUND: The electroencephalogram (EEG) is a widely used laboratory technique in rodent models of epilepsy, traumatic brain injury (TBI), and other neurological diseases accompanied by seizures. Obtaining prolonged continuous EEG tracings over weeks to ... Full text Link to item Cite

Lestaurtinib (CEP-701) modulates the effects of early life hypoxic seizures on cognitive and emotional behaviors in immature rats.

Journal Article Epilepsy Behav · March 2019 Hypoxic encephalopathy of the newborn is a major cause of long-term neurological sequelae. We have previously shown that CEP-701 (lestaurtinib), a drug with an established safety profile in children, attenuates short-term hyperexcitability and tropomyosin- ... Full text Link to item Cite

Overview on Emotional Behavioral Testing in Rodent Models of Pediatric Epilepsy.

Chapter · 2019 Psychiatric and cognitive disturbances are the most common comorbidities of epileptic disorders in children. The successful treatment of these comorbidities faces many challenges including their etiologically heterogonous nature. Translational neurobehavio ... Full text Link to item Cite

Methods in Electrode Implantation and Wiring for Long-Term Continuous EEG Monitoring in Rodent Models of Epilepsy and Behavioral Disturbances.

Chapter · 2019 Rodent seizure models that pathologically and behaviorally recapitulate age-tailored epileptic disorders are used by us and others to advance our understanding of the chronobiology and mechanisms of epileptic seizure emergence and their comorbidities and t ... Full text Link to item Cite

A child with hyperekplexia and epileptic myoclonus.

Journal Article Epileptic Disord · August 1, 2018 Hyperekplexia is a rare neurogenetic disorder characterized by startle. Accurate diagnosis of this notorious mimicker of epilepsy is important to prevent life-threatening apnoea. We report a novel case of concomitant GLRA1-related hyperkeplexia and myoclon ... Full text Link to item Cite

Activating BRAF Mutations Detected in Mixed Hürthle Cell Carcinoma and Multifocal Papillary Carcinoma of the Thyroid Gland: Report of an Unusual Case and Review of the Literature.

Journal Article Int J Surg Pathol · September 2016 Despite the increase in the incidence of thyroid carcinomas, the occurrence of collision tumors in the thyroid remains a rare event. We present the case of a 69-year-old female who presented to the emergency department with a chief complaint of painful nec ... Full text Link to item Cite