Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Clinical Research Training Program, Duke University School of Medicine 2015 - 2016
  • Fellowship in Electrophysiology, Duke University School of Medicine 2015 - 2016
  • Fellowship in Clinical Research, Duke Clinical Research Institute, Duke University School of Medicine 2013 - 2015
  • Fellowship in Electrophysiology, Medicine, Duke University School of Medicine 2012 - 2013
  • Fellowship in Cardiovascular Medicine, Medicine, Duke University School of Medicine 2010 - 2012
  • Internal Medicine Internship and Residency, Medicine, Duke University School of Medicine 2007 - 2010
  • M.D., University of Florida, College of Medicine 2007
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2018 - 2020
  • Medical Instructor in the Department of Medicine, Medicine, Cardiology, Medicine 2016 - 2018
• Research
• 

  Selected Grants

  • VIVID awarded by Patient Centered Outcomes Research Institute 2017 - 2020
• 

  External Relationships

  • Covidien (Medtronic)
  • Medtronic (Covidien)
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Jackson, Larry R., Peter Schrader, Laine Thomas, Benjamin A. Steinberg, Rosalia Blanco, Larry A. Allen, Gregg C. Fonarow, et al. “Dosing of Direct Oral Anticoagulants in Patients with Moderate Chronic Kidney Disease in US Clinical Practice: Results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF II).” Am J Cardiovasc Drugs 21, no. 5 (September 2021): 553–61. https://doi.org/10.1007/s40256-021-00473-x.
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    • Kennedy, Danielle L., Maren K. Olsen, Hongqiu Yang, Xiaomei Gao, Aviel Alkon, Neil S. Prose, Kayla Dunbar, Larry R. Jackson, and Kathryn I. Pollak. “Communication Coaching in Cardiology (CCC): A study protocol and methodological challenges and solutions of a randomized controlled trial in outpatient cardiology clinics.” Contemp Clin Trials 105 (June 2021): 106389. https://doi.org/10.1016/j.cct.2021.106389.
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    • Jackson, Larry R., Kevin P. Jackson, and Kevin L. Thomas. “Percutaneous left atrial appendage occlusion: A review of current devices, clinical evidence, patient selection, and post procedural antithrombotic management.” Prog Cardiovasc Dis 66 (May 2021): 92–100. https://doi.org/10.1016/j.pcad.2021.06.006.
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    • Yankey, George S., Larry R. Jackson, Colin Marts, Karen Chiswell, Angie Wu, Francis Ugowe, Jimica Wilson, Sreekanth Vemulapalli, Zainab Samad, and Kevin L. Thomas. “African American-Caucasian American differences in aortic valve replacement in patients with severe aortic stenosis.” Am Heart J 234 (April 2021): 111–21. https://doi.org/10.1016/j.ahj.2021.01.005.
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    • Mason, Pamela K., Akshay Desai, Olujimi A. Ajijola, Anish K. Amin, Chirag Barbhaiya, Anuj Basil, Ralph DeBiasi, et al. “Integrated electrophysiology care for patients with heart failure: An envisioned future.” Heart Rhythm 18, no. 2 (February 2021): e51–63. https://doi.org/10.1016/j.hrthm.2020.10.008.
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    • Rymer, Jennifer A., Camille G. Frazier-Mills, Larry R. Jackson, Kevin L. Thomas, Pamela S. Douglas, Andrew Wang, Manesh R. Patel, and Anna Lisa Crowley. “Evaluation of Women and Underrepresented Racial and Ethnic Group Representation in a General Cardiology Fellowship After a Systematic Recruitment Initiative.” Jama Netw Open 4, no. 1 (January 4, 2021): e2030832. https://doi.org/10.1001/jamanetworkopen.2020.30832.
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    • Chery, Godefroy, Larry Jackson, and Kevin L. Thomas. “Letter to the Editor: Inappropriate subcutaneous implantable cardioverter-defibrillator discharge related to myopotential oversensing.” J Arrhythm 36, no. 5 (October 2020): 948–49. https://doi.org/10.1002/joa3.12415.
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    • Jackson, Larry R., Sunghee Kim, Rosalia Blanco, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, et al. “Discontinuation rates of warfarin versus direct acting oral anticoagulants in US clinical practice: Results from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II).” Am Heart J 226 (August 2020): 85–93. https://doi.org/10.1016/j.ahj.2020.04.016.
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    • Wang, Allen, Tracy Truong, Eric Black-Maier, Cynthia Green, Kristen B. Campbell, Adam S. Barnett, Janice Febre, et al. “Catheter ablation of atrial fibrillation in patients with diabetes mellitus.” Heart Rhythm O2 1, no. 3 (August 2020): 180–88. https://doi.org/10.1016/j.hroo.2020.04.006.
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    • Black-Maier, Eric, Benjamin A. Steinberg, Kevin M. Trulock, Frances Wang, Yuliya Lokhnygina, Wanda O’Neal, Sana Al-Khatib, et al. “Effectiveness of catheter ablation of atrial fibrillation according to heart failure etiology.” J Arrhythm 36, no. 1 (February 2020): 84–92. https://doi.org/10.1002/joa3.12291.
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    • Sutter, Joanne S., Yuliya Lokhnygina, James P. Daubert, Tristram Bahnson, Kevin Jackson, Jason I. Koontz, Albert Y. Sun, et al. “Safety and efficacy outcomes of left atrial posterior wall isolation compared to pulmonary vein isolation and pulmonary vein isolation with linear ablation for the treatment of persistent atrial fibrillation.” Am Heart J 220 (February 2020): 89–96. https://doi.org/10.1016/j.ahj.2019.11.010.
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    • Thomas, Kevin L., Lonnie T. Sullivan, Sana M. Al-Khatib, Nancy Allen LaPointe, Sam Sears, Andrzej S. Kosinski, Larry R. Jackson, Valentina Kutyifa, and Eric D. Peterson. “Videos to reduce racial disparities in ICD therapy Via Innovative Designs (VIVID) trial: Rational, design and methodology.” Am Heart J 220 (February 2020): 59–67. https://doi.org/10.1016/j.ahj.2019.10.011.
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    • Wilson, Jimica B., Larry R. Jackson, Francis E. Ugowe, Terrell Jones, George S. A. Yankey, Colin Marts, and Kevin L. Thomas. “Racial and Ethnic Differences in Treatment and Outcomes of Severe Aortic Stenosis: A Review.” Jacc Cardiovasc Interv 13, no. 2 (January 27, 2020): 149–56. https://doi.org/10.1016/j.jcin.2019.08.056.
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    • Black-Maier, Eric, Alice Parish, Benjamin A. Steinberg, Cynthia L. Green, Zak Loring, Adam S. Barnett, Sana M. Al-Khatib, et al. “Predicting atrial fibrillation recurrence after ablation in patients with heart failure: Validity of the APPLE and CAAP-AF risk scoring systems.” Pacing Clin Electrophysiol 42, no. 11 (November 2019): 1440–47. https://doi.org/10.1111/pace.13805.
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    • Sullivan, Lonnie T., Hillary Mulder, Karen Chiswell, Linda K. Shaw, Tracy Y. Wang, Larry R. Jackson, and Kevin L. Thomas. “Racial differences in long-term outcomes among black and white patients with drug-eluting stents.” Am Heart J 214 (August 2019): 46–53. https://doi.org/10.1016/j.ahj.2019.04.005.
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    • Linares, Jered D., Larry R. Jackson, Farah Z. Dawood, Katrina Swett, Emelia J. Benjamin, Neil Schneiderman, Elsayed Z. Soliman, et al. “Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: The Hispanic Community Health Study/Study of Latinos.” Heart Rhythm 16, no. 5 (May 2019): 686–93. https://doi.org/10.1016/j.hrthm.2018.11.033.
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    • Ugowe, Francis E., Larry R. Jackson, and Kevin L. Thomas. “Atrial Fibrillation and Diabetes Mellitus: Can We Modify Stroke Risk Through Glycemic Control?” Circ Arrhythm Electrophysiol 12, no. 5 (May 2019): e007351. https://doi.org/10.1161/CIRCEP.119.007351.
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    • Egwim, Chidiebube C., Alvin J. Rucker, Deng C. Madut, Goderfroy S. Chery, Lonnie T. Sullivan, Larry R. Jackson, Wayne B. Batchelor, and Kevin L. Thomas. “Research Participation of a Professional Organization in Clinical Trials: The Association of Black cardiologists Clinical Trial Investigator Identification Project.” J Natl Med Assoc 111, no. 2 (April 2019): 122–33. https://doi.org/10.1016/j.jnma.2018.07.004.
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    • Essien, Utibe R., and Larry R. Jackson. “Race Effects in CVD Prediction Models.” J Gen Intern Med 34, no. 4 (April 2019): 484. https://doi.org/10.1007/s11606-018-4789-8.
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    • Starks, Monique Anderson, Gillian D. Sanders, Remy Rene Coeytaux, Isaretta L. Riley, Larry R. Jackson, Amanda McBroom Brooks, Kevin L. Thomas, Kingshuk Roy Choudhury, Robert M. Califf, and Adrian F. Hernandez. “Assessing heterogeneity of treatment effect analyses in health-related cluster randomized trials: A systematic review.” Plos One 14, no. 8 (2019): e0219894. https://doi.org/10.1371/journal.pone.0219894.
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    • Ugowe, Francis E., and Larry R. Jackson. “Atrial fibrillation and mortality risk: seeing the big picture.” Eur Heart J Qual Care Clin Outcomes 5, no. 1 (January 1, 2019): 6–7. https://doi.org/10.1093/ehjqcco/qcy050.
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    • Essien, Utibe R., DaJuanicia N. Holmes, Larry R. Jackson, Gregg C. Fonarow, Kenneth W. Mahaffey, James A. Reiffel, Benjamin A. Steinberg, et al. “Association of Race/Ethnicity With Oral Anticoagulant Use in Patients With Atrial Fibrillation: Findings From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II.” Jama Cardiol 3, no. 12 (December 1, 2018): 1174–82. https://doi.org/10.1001/jamacardio.2018.3945.
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    • Jackson, Larry R., Sunghee Kim, Peter Shrader, Rosalia Blanco, Laine Thomas, Michael D. Ezekowitz, Jack Ansell, et al. “Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry.” J Thromb Thrombolysis 46, no. 4 (November 2018): 435–39. https://doi.org/10.1007/s11239-018-1715-1.
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    • Jackson, Larry R., Kevin L. Thomas, Bronislava Polonsky, Wojciech Zareba, Marc Lahiri, Samir Saba, Scott McNitt, et al. “Effectiveness of high rate and delayed detection ICD programming by race: A MADIT-RIT substudy.” J Cardiovasc Electrophysiol 29, no. 10 (October 2018): 1418–24. https://doi.org/10.1111/jce.13693.
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    • Ugowe, Francis E., Larry R. Jackson, and Kevin L. Thomas. “Racial and ethnic differences in the prevalence, management, and outcomes in patients with atrial fibrillation: A systematic review.” Heart Rhythm 15, no. 9 (September 2018): 1337–45. https://doi.org/10.1016/j.hrthm.2018.05.019.
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    • Jackson, Larry R., Sunghee Kim, Gregg C. Fonarow, James V. Freeman, Bernard J. Gersh, Alan S. Go, Elaine M. Hylek, et al. “Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHA2DS2-VASc Scores: Findings From the ORBIT-AF I and II Registries.” J Am Heart Assoc 7, no. 16 (August 21, 2018): e008764. https://doi.org/10.1161/JAHA.118.008764.
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    • Holmqvist, F., B. Rathakrishnan, L. R. Jackson, K. Campbell, and J. P. Daubert. “Pacemaker programming in patients with first-degree AV-block: Programming pattern and possible consequences.” Health Sci Rep 1, no. 6 (June 2018): e39. https://doi.org/10.1002/hsr2.39.
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    • Black-Maier, Eric, Xinru Ren, Benjamin A. Steinberg, Cynthia L. Green, Adam S. Barnett, Normita Sta Rosa, Sana M. Al-Khatib, et al. “Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction.” Heart Rhythm 15, no. 5 (May 2018): 651–57. https://doi.org/10.1016/j.hrthm.2017.12.001.
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    • Al-Shahi Salman, Rustam, Martin S. Dennis, Gordon D. Murray, Karen Innes, Jonathan Drever, Lynn Dinsmore, Carol Williams, et al. “The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial.” Trials 19, no. 1 (March 5, 2018): 162. https://doi.org/10.1186/s13063-018-2542-6.
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    • Sullivan, Lonnie T., Tiffany Randolph, Peter Merrill, Larry R. Jackson, Chidiebube Egwim, Monique A. Starks, and Kevin L. Thomas. “Representation of black patients in randomized clinical trials of heart failure with reduced ejection fraction.” Am Heart J 197 (March 2018): 43–52. https://doi.org/10.1016/j.ahj.2017.10.025.
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    • Thomas, Kevin L., Larry R. Jackson, Peter Shrader, Jack Ansell, Gregg C. Fonarow, Bernard Gersh, Peter R. Kowey, et al. “Prevalence, Characteristics, and Outcomes of Valvular Heart Disease in Patients With Atrial Fibrillation: Insights From the ORBIT-AF (Outcomes Registry for Better Informed Treatment for Atrial Fibrillation).” J Am Heart Assoc 6, no. 12 (December 22, 2017). https://doi.org/10.1161/JAHA.117.006475.
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    • Jackson, Larry R., Bharath Rathakrishnan, Kristen Campbell, Kevin L. Thomas, Jonathan P. Piccini, Tristram Bahnson, Jonathan A. Stiber, and James P. Daubert. “Sinus Node Dysfunction and Atrial Fibrillation: A Reversible Phenomenon?” Pacing Clin Electrophysiol 40, no. 4 (April 2017): 442–50. https://doi.org/10.1111/pace.13030.
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    • Jackson, Larry R., Eric D. Peterson, Lisa A. McCoy, Christine Ju, Marjorie Zettler, Brian A. Baker, John C. Messenger, et al. “Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study.” J Am Heart Assoc 5, no. 10 (October 21, 2016). https://doi.org/10.1161/JAHA.116.003824.
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    • Jackson, Larry R., Jonathan P. Piccini, Derek D. Cyr, Matthew T. Roe, Megan L. Neely, Felipe Martinez, Thomas F. Lüscher, et al. “Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial.” Clin Cardiol 39, no. 9 (September 2016): 497–506. https://doi.org/10.1002/clc.22562.
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    • Sabbag, Avi, Ilan Goldenberg, Arthur J. Moss, Scott McNitt, Michael Glikson, Yitschak Biton, Larry Jackson, Bronislava Polonsky, Wojciech Zareba, and Valentina Kutyifa. “Predictors and Risk of Ventricular Tachyarrhythmias or Death in Black and White Cardiac Patients: A MADIT-CRT Trial Substudy.” Jacc Clin Electrophysiol 2, no. 4 (August 2016): 448–55. https://doi.org/10.1016/j.jacep.2016.03.003.
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    • Sullivan, Lonnie T., Larry R. Jackson, and Kevin L. Thomas. “Review of venous thromboembolism and race: the generalizability of treatment guidelines for high-risk populations.” J Thromb Thrombolysis 42, no. 2 (August 2016): 167–71. https://doi.org/10.1007/s11239-016-1352-5.
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    • Mentz, Robert J., L Kristin Newby, Ben Neely, Joseph E. Lucas, Sean D. Pokorney, Meena P. Rao, Larry R. Jackson, et al. “Assessment of Administrative Data to Identify Acute Myocardial Infarction in Electronic Health Records.” J Am Coll Cardiol 67, no. 20 (May 24, 2016): 2441–42. https://doi.org/10.1016/j.jacc.2016.03.511.
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    • Golwala, Harsh, Larry R. Jackson, DaJuanicia N. Simon, Jonathan P. Piccini, Bernard Gersh, Alan S. Go, Elaine M. Hylek, et al. “Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: Insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry.” Am Heart J 174 (April 2016): 29–36. https://doi.org/10.1016/j.ahj.2015.10.028.
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    • Jackson, Larry R., Sung Hee Kim, Jonathan P. Piccini, Bernard J. Gersh, Gerald V. Naccarelli, James A. Reiffel, James Freeman, et al. “Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT-AF Registry.” Clin Cardiol 39, no. 2 (February 2016): 119–25. https://doi.org/10.1002/clc.22504.
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    • Jackson, Larry R., Christine Ju, Marjorie Zettler, John C. Messenger, David J. Cohen, Gregg W. Stone, Brian A. Baker, Mark Effron, Eric D. Peterson, and Tracy Y. Wang. “Outcomes of Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention Receiving an Oral Anticoagulant and Dual Antiplatelet Therapy: A Comparison of Clopidogrel Versus Prasugrel From the TRANSLATE-ACS Study.” Jacc Cardiovasc Interv 8, no. 14 (December 21, 2015): 1880–89. https://doi.org/10.1016/j.jcin.2015.08.018.
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    • Jackson, Larry R., Jonathan P. Piccini, James P. Daubert, Lynne M. Hurwitz Koweek, and Brett D. Atwater. “Localization of pacing and defibrillator leads using standard x-ray views is frequently inaccurate and is not reproducible.” J Interv Card Electrophysiol 43, no. 1 (June 2015): 5–12. https://doi.org/10.1007/s10840-015-9984-5.
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    • Jackson, Larry R., Eric D. Peterson, Eze Okeagu, and Kevin Thomas. “Review of race/ethnicity in non vitamin K antagonist oral anticoagulants clinical trials.” J Thromb Thrombolysis 39, no. 2 (February 2015): 222–27. https://doi.org/10.1007/s11239-014-1145-7.
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    • Jackson, Larry R., Sung Hee Kim, Jonathan P. Piccini, Bernard J. Gersh, Gerald V. Naccarelli, James A. Reiffel, James Freeman, et al. “Sinus Node Dysfunction in Associated With Higher Symptom Burden and Increased Risk of Progression to Permanent Atrial Fibrillation: Results From ORBIT-AF Registry.” Circulation 130 (November 25, 2014).
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    • Jackson, Larry R., and Richard C. Becker. “Novel oral anticoagulants: pharmacology, coagulation measures, and considerations for reversal.” J Thromb Thrombolysis 37, no. 3 (April 2014): 380–91. https://doi.org/10.1007/s11239-013-0958-0.
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    • Jackson, Larry R., James P. Daubert, and Kevin L. Thomas. “Expanding the benefits of implantable cardioverter-defibrillator therapy: "is less more"?” Prog Cardiovasc Dis 54, no. 4 (January 2012): 372–78. https://doi.org/10.1016/j.pcad.2011.11.002.
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  • Conference Papers

    • Yankey, George, Zainab Samad, Angie Wu, Karen Chiswell, Larry Jackson, Jimica Wilson, Terrell Jones, and Kevin Thomas. “AORTIC VALVE REPLACEMENT AND OUTCOMES IN PATIENTS WITH SEVERE AORTIC STENOSIS: IS IT BLACK OR WHITE?” In Journal of the American College of Cardiology, 71:A2010–A2010. Elsevier BV, 2018. https://doi.org/10.1016/s0735-1097(18)32551-8.
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    • Jackson, Larry R., Sunghee Kim, Jack Ansell, Gregg Fonarow, James Freeman, Bernard Gersh, Alan Go, et al. “TREATMENT AND STROKE RISK IN LOW RISK CHA2DS2VASC ATRIAL FIBRILLATION PATIENTS: FINDINGS FROM THE ORBIT-AF REGISTRY.” In Journal of the American College of Cardiology, 67:788–788. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30789-6.
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    • Golwala, Harsh, Larry Jackson, DaJuanicia Simon, Gregg Fonarow, Paul Chang, Bernard Gersh, Alan Go, et al. “RACIAL/ETHNIC DIFFERENCES IN ATRIAL FIBRILLATION SYMPTOMS, TREATMENT PATTERNS, AND OUTCOMES: INSIGHTS FROM OUTCOMES REGISTRY FOR BETTER INFORMED TREATMENT FOR ATRIAL FIBRILLATION (ORBIT-AF) REGISTRY.” In Journal of the American College of Cardiology, 65:A462–A462. Elsevier BV, 2015. https://doi.org/10.1016/s0735-1097(15)60462-4.
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