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Larry Ronald Jackson II

Associate Professor of Medicine
Medicine, Cardiology
300 W Morgan Street, Office 635, Durham, NC 27701

Overview


Dr. Jackson is a physician-scientist with clinical expertise in adult clinical cardiac electrophysiology. His research focuses on identifying determinants of racial/ethnic differences in arrhythmia care and the development and implementation of patient-centered interventions aimed at facilitating shared decision-making in populations that have been systemically disadvantaged with abnormal heart rhythm conditions. Dr. Jackson has an advanced degree (MHSc) in clinical and qualitative research methodology and is a member of the Duke Clinical Research Institute. His research skills, obtained during his time at the Duke Clinical Research Institute Research Fellowship, include formal training in large database analysis, clinical trial operations, scientific writing, clinical trial adjudication and statistical analysis. Dr. Jackson’s research funding consists of two career development awards: 1) National Institute of Health/National Heart, Lung, and Blood Institute-K01 focused on racial and ethnic differences in oral anticoagulation use in patients with atrial fibrillation and 2) AHA career development award focused on analyzing racial and ethnic differences in the use of rhythm control strategies in patients with atrial fibrillation.  Dr. Jackson’s long-term, overarching goal as a physician-scientist is to decrease racial and ethnic disparities in arrhythmia care for patients with abnormal heart rhythm conditions.

Current Appointments & Affiliations


Associate Professor of Medicine · 2022 - Present Medicine, Cardiology, Medicine
Member in the Duke Clinical Research Institute · 2021 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Atrial fibrillation in the Americas

Journal Article Lancet Regional Health Americas · July 1, 2025 Atrial Fibrillation is the most common sustained cardiac arrhythmia, and is associated with significant impairments in quality of life. Regional variations and challenges in the management of atrial fibrillation are present throughout the Americas. Atrial ... Full text Cite

Evolving Indications, Challenges and Advances in Cardiac Resynchronization Therapy for Heart Failure.

Journal Article J Card Fail · April 16, 2025 Cardiac resynchronization therapy (CRT) via biventricular pacing has markedly improved heart failure outcomes over the past 2 decades. However, some patients show no clinical improvement or evidence of reverse remodeling following device implantation. Chal ... Full text Link to item Cite

Use of a Stylet Driven Lead With a Flexible Neck for Left Bundle Branch Area Pacing: A Single Center Experience.

Journal Article J Cardiovasc Electrophysiol · April 2025 BACKGROUND: The majority of data on left bundle branch area pacing (LBBAP) are on a lumenless lead. Data on the safety and effectiveness of stylet driven leads are comparatively lacking. METHODS: We retrospectively analyzed 265 patients who underwent attem ... Full text Link to item Cite
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Recent Grants


Machine Learning Guided Precision Genetic Testing for Identification of Monogenic Cardiovascular Disorders

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2024 - 2028

Shared Decision-Making to Reduce Racial Disparities in Oral Anticoagulation Use in Patients with Non-Valvular Atrial Fibrillation (K01)

ResearchPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 2021 - 2026

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Education, Training & Certifications


University of Florida, College of Medicine · 2007 M.D.