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Laura Eloise Rupprecht

Adjunct Assistant Professor in the Department of Medicine
Medicine, Gastroenterology

Current Appointments & Affiliations


Adjunct Assistant Professor in the Department of Medicine · 2025 - Present Medicine, Gastroenterology, Medicine

Recent Publications


A gut sense for a microbial pattern regulates feeding.

Journal Article Nature · September 2025 To coexist with its resident microorganisms, the host must have a sense to adjust its behaviour in response to them. In the intestine, a sense for nutrients transduced to the brain through neuroepithelial circuits guides appetitive choices1-5. However, a s ... Full text Link to item Cite

Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits.

Journal Article Nat Biotechnol · June 2024 Progress in understanding brain-viscera interoceptive signaling is hindered by a dearth of implantable devices suitable for probing both brain and peripheral organ neurophysiology during behavior. Here we describe multifunctional neural interfaces that com ... Full text Link to item Cite

Evaluation of Flavor Effects on Oral Nicotine Liking and/or Disliking Using the Taste Reactivity Test in Rats.

Journal Article Nicotine Tob Res · March 26, 2022 INTRODUCTION: Tobacco product flavors may change the sensory properties of nicotine, such as taste and olfactory cues, which may alter nicotine reward and aversion and nicotine taking behavior. The hedonic or aversive value of a taste stimulus can be evalu ... Full text Link to item Cite
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Recent Grants


Gut epithelial control of nutrient reward

ResearchPrincipal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028

Harnessing the neuroepithelial gut-brain circuit in binge eating disorder

ResearchPI-Fellow · Awarded by Brain and Behavior Research Foundation · 2024 - 2026

The efferent synapse in neuropod cells

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2019 - 2024

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Education, Training & Certifications


University of Pittsburgh · 2017 Ph.D.