Lauren Howard

Lauren collaborates with different investigators in the Duke Cancer Institute on retrospective studies and clinical trials. She has experience with data management, data analysis, and preparation and editing of manuscripts. Some of her past projects have involved time-varying covariates, competing risks, and repeated measures. She is interested in methods for handling bias and confounding in observational research.

Current Appointments & Affiliations

Biostatistician, Senior Biostatistics & Bioinformatics, Basic Science Departments

Recent Publications

Genetic ancestry-concordant ceramide metabolism and response to androgen receptor pathway inhibition in metastatic castration-resistant prostate cancer.

Journal Article Cancer · June 1, 2026 BACKGROUND: The authors observed differences in response between Black and White patients with metastatic castration-resistant prostate cancer (mCRPC) who were treated prospectively with androgen receptor pathway inhibition (ARPI) in the Abi Race and PANTH ... Full text Link to item Cite

Monitoring treatment response using an ultra-sensitive ctDNA assay in advanced esophagogastric cancer patients.

Journal Article Sci Rep · March 23, 2026 To explore whether ultra-sensitive circulating tumor DNA (ctDNA) profiling enables earlier prediction of treatment response and detection of disease progression, we applied NeXT Personal, an ultra-sensitive bespoke tumor-informed liquid biopsy platform, to ... Full text Link to item Cite

Outcomes for Patients With SPOP Mutated Castration-Resistant Prostate Cancer (CRPC) Treated With an Androgen Receptor Pathway Inhibitor (ARPI).

Journal Article Clin Genitourin Cancer · March 2026 INTRODUCTION: Inactivating missense mutations in the SPOP gene increase the transcriptional activity of the androgen receptor and sensitivity to hormonal therapies in patients with hormone sensitive prostate cancer (HSPC). However, the relationship of SPOP ... Full text Link to item Cite

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