Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Cardiology, Medicine, Duke University 1999 - 2003
  • Medical Resident, Medicine, Vanderbilt University 1996 - 1999
  • M.D., Duke University 1996
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2011 - 2020
  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2003 - 2011
  • Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2003
• Expertise
• 

  Global Scholarship

  • Research

    • China (Country) 
    • South Africa (Country) 
• Research
• 

  Selected Grants

  • Lifestyle, CVD Risk and Cognitive Impairment awarded by National Institutes of Health 2011 - 2018
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial.” J Cardiovasc Dev Dis 9, no. 10 (September 22, 2022). https://doi.org/10.3390/jcdd9100320.
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    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Longer term benefits of exercise and escitalopram in the treatment of anxiety in patients with coronary heart disease: Six month follow-up of the UNWIND randomized clinical trial.” Am Heart J 251 (September 2022): 91–100. https://doi.org/10.1016/j.ahj.2022.05.014.
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    • Smith, Patrick J., Andrew Sherwood, Alan L. Hinderliter, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.” J Hypertens 40, no. 7 (July 1, 2022): 1359–68. https://doi.org/10.1097/HJH.0000000000003151.
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    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, Lawrence Liao, Jonathan Davidson, and Andrew Sherwood. “Effect of Exercise, Escitalopram, or Placebo on Anxiety in Patients With Coronary Heart Disease: The Understanding the Benefits of Exercise and Escitalopram in Anxious Patients With Coronary Heart Disease (UNWIND) Randomized Clinical Trial.” Jama Psychiatry 78, no. 11 (November 1, 2021): 1270–78. https://doi.org/10.1001/jamapsychiatry.2021.2236.
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    • Blumenthal, James A., Alan L. Hinderliter, Patrick J. Smith, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.” Circulation 144, no. 15 (October 2021): 1212–26. https://doi.org/10.1161/circulationaha.121.055329.
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    • Atwater, Brett D., Kasper Emerek, Zainab Samad, Edward Sze, Eric Black-Maier, Zak Loring, Martin Ugander, et al. “Predicting the Development of Reduced Left Ventricular Ejection Fraction in Patients With Left Bundle Branch Block.” Am J Cardiol 137 (December 15, 2020): 39–44. https://doi.org/10.1016/j.amjcard.2020.09.034.
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    • Geurink, Kyle R., Christopher B. Granger, Lawrence Liao, Neel G. Thomas, Benjamin C. Lindsey, Elizabeth Babin, Natalie Turgeon, Justine Alexander, and Sean D. Pokorney. “A reversal of fortune: A case of cardiovascular collapse following protamine sulfate infusion.” Heartrhythm Case Rep 6, no. 6 (June 2020): 322–24. https://doi.org/10.1016/j.hrcr.2020.02.008.
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    • Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Pao-Hwa Lin, Lawrence Liao, Kathleen A. Welsh-Bohmer, et al. “Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.” Neurology 92, no. 3 (January 15, 2019): e212–23. https://doi.org/10.1212/WNL.0000000000006784.
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    • Main, Michael L., Dali Fan, Vivek Y. Reddy, David R. Holmes, Nicole T. Gordon, Tina R. Coggins, John A. House, et al. “Assessment of Device-Related Thrombus and Associated Clinical Outcomes With the WATCHMAN Left Atrial Appendage Closure Device for Embolic Protection in Patients With Atrial Fibrillation (from the PROTECT-AF Trial).” Am J Cardiol 117, no. 7 (April 1, 2016): 1127–34. https://doi.org/10.1016/j.amjcard.2016.01.039.
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    • Sivak, Joseph A., Amit N. Vora, Ann Marie Navar, Phillip J. Schulte, Anna Lisa Crowley, Joseph Kisslo, G Ralph Corey, et al. “An Approach to Improve the Negative Predictive Value and Clinical Utility of Transthoracic Echocardiography in Suspected Native Valve Infective Endocarditis.” J Am Soc Echocardiogr 29, no. 4 (April 2016): 315–22. https://doi.org/10.1016/j.echo.2015.12.009.
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    • Blumenthal, James A., Andrew Sherwood, Patrick J. Smith, Stephanie Mabe, Lana Watkins, Pao-Hwa Lin, Linda W. Craighead, et al. “Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.” Am Heart J 170, no. 5 (November 2015): 986-994.e5. https://doi.org/10.1016/j.ahj.2015.08.006.
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    • Daubert, Melissa A., Joseph Massaro, Lawrence Liao, Ashish Pershad, Suresh Mulukutla, Erik Magnus Ohman, Jeffrey Popma, William W. O’Neill, and Pamela S. Douglas. “High-risk percutaneous coronary intervention is associated with reverse left ventricular remodeling and improved outcomes in patients with coronary artery disease and reduced ejection fraction.” American Heart Journal 170, no. 3 (September 2015): 550–58. https://doi.org/10.1016/j.ahj.2015.06.013.
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    • Liao, L., D. F. Kong, Z. Samad, P. A. Pappas, J. G. Jollis, S. S. Lin, A. Wang, et al. “Echocardiographic risk stratification for early surgery with endocarditis: a cost-effectiveness analysis.” Heart 94, no. 5 (May 2008): e18. https://doi.org/10.1136/hrt.2006.106716.
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    • Rao, Sunil V., Padma R. Kaul, Lawrence Liao, Paul W. Armstrong, E Magnus Ohman, Christopher B. Granger, Robert M. Califf, Robert A. Harrington, Eric L. Eisenstein, and Daniel B. Mark. “Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes.” Am Heart J 155, no. 2 (February 2008): 369–74. https://doi.org/10.1016/j.ahj.2007.10.014.
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    • Curtis, Lesley H., Bradley G. Hammill, M Angelyn Bethel, Kevin J. Anstrom, Lawrence Liao, John S. Gottdiener, and Kevin A. Schulman. “Pancreatic beta-cell function as a predictor of cardiovascular outcomes and costs: findings from the Cardiovascular Health Study.” Curr Med Res Opin 24, no. 1 (January 2008): 41–50. https://doi.org/10.1185/030079908x253573.
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    • Liao, Lawrence, Larry A. Allen, and David J. Whellan. “Economic burden of heart failure in the elderly.” Pharmacoeconomics 26, no. 6 (2008): 447–62. https://doi.org/10.2165/00019053-200826060-00001.
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    • Liao, Lawrence. “Benefits of coronary revascularization: a failure to communicate.” Am Heart J 154, no. 4 (October 2007): 613–14. https://doi.org/10.1016/j.ahj.2007.06.021.
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    • Liao, Lawrence, Kevin J. Anstrom, John S. Gottdiener, Paul A. Pappas, David J. Whellan, Dalane W. Kitzman, Gerard P. Aurigemma, Daniel B. Mark, Kevin A. Schulman, and James G. Jollis. “Long-term costs and resource use in elderly participants with congestive heart failure in the Cardiovascular Health Study.” Am Heart J 153, no. 2 (February 2007): 245–52. https://doi.org/10.1016/j.ahj.2006.11.010.
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    • Whellan, David J., Shelby D. Reed, Lawrence Liao, Stuart D. Gould, Christopher M. O’connor, and Kevin A. Schulman. “Financial implications of a model heart failure disease management program for providers, hospital, healthcare systems, and payer perspectives.” Am J Cardiol 99, no. 2 (January 15, 2007): 256–60. https://doi.org/10.1016/j.amjcard.2006.08.019.
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    • Liao, Lawrence, James G. Jollis, Kevin J. Anstrom, David J. Whellan, Dalane W. Kitzman, Gerard P. Aurigemma, Daniel B. Mark, Kevin A. Schulman, and John S. Gottdiener. “Costs for heart failure with normal vs reduced ejection fraction.” Arch Intern Med 166, no. 1 (January 9, 2006): 112–18. https://doi.org/10.1001/archinte.166.1.112.
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    • Halabi, Abdul R., John H. Alexander, Linda K. Shaw, Todd J. Lorenz, Lawrence Liao, David F. Kong, Carmelo A. Milano, Robert A. Harrington, and Peter K. Smith. “Relation of early saphenous vein graft failure to outcomes following coronary artery bypass surgery.” Am J Cardiol 96, no. 9 (November 1, 2005): 1254–59. https://doi.org/10.1016/j.amjcard.2005.06.067.
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    • Liao, Lawrence, David F. Kong, Linda K. Shaw, Michael H. Sketch, Carmelo A. Milano, Kerry L. Lee, and Daniel B. Mark. “A new anatomic score for prognosis after cardiac catheterization in patients with previous bypass surgery.” J Am Coll Cardiol 46, no. 9 (November 1, 2005): 1684–92. https://doi.org/10.1016/j.jacc.2005.06.074.
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    • Liao, Lawrence, Antonio Sarria-Santamera, David B. Matchar, Ayn Huntington, Shu Lin, David J. Whellan, and David F. Kong. “Meta-analysis of survival and relief of angina pectoris after transmyocardial revascularization.” Am J Cardiol 95, no. 10 (May 15, 2005): 1243–45. https://doi.org/10.1016/j.amjcard.2005.01.057.
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    • Liao, Lawrence, William T. Smith, Robert H. Tuttle, Linda K. Shaw, R Edward Coleman, and Salvador Borges-Neto. “Prediction of death and nonfatal myocardial infarction in high-risk patients: a comparison between the Duke treadmill score, peak exercise radionuclide angiography, and SPECT perfusion imaging.” J Nucl Med 46, no. 1 (January 2005): 5–11.
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    • Liao, Lawrence, Christopher H. Cabell, James G. Jollis, Eric J. Velazquez, William T. Smith, Kevin J. Anstrom, Paul A. Pappas, Thomas Ryan, Joseph A. Kisslo, and Carolyn K. Landolfo. “Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization.” Am J Cardiol 93, no. 10 (May 15, 2004): 1275–79. https://doi.org/10.1016/j.amjcard.2004.01.071.
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    • Liao, Lawrence, David J. Whellan, Katsuhiko Tabuchi, and Kevin A. Schulman. “Differences in care-seeking behavior for acute chest pain in the United States and Japan.” Am Heart J 147, no. 4 (April 2004): 630–35. https://doi.org/10.1016/j.ahj.2003.10.006.
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    • Liao, Lawrence, and Daniel B. Mark. “Clinical prediction models: are we building better mousetraps?” J Am Coll Cardiol 42, no. 5 (September 3, 2003): 851–53. https://doi.org/10.1016/s0735-1097(03)00836-2.
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    • Liao, L., M. K. Bundorf, T. Kauf, K. A. Schulman, D. Whellan, and J. Jollis. “PCV37: BASELINE PREDICTORS OF ONE-YEAR COSTS AFTER ACUTE MYOCARDIAL INFARCTION IN THE ELDERLY.” Value in Health 6, no. 3 (May 2003): 320–320. https://doi.org/10.1016/s1098-3015(10)64151-4.
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    • Bulsara, Ketan R., Matthew J. McGirt, Lawrence Liao, Alan T. Villavicencio, Cecil Borel, Michael J. Alexander, and Allan H. Friedman. “Use of the peak troponin value to differentiate myocardial infarction from reversible neurogenic left ventricular dysfunction associated with aneurysmal subarachnoid hemorrhage.” J Neurosurg 98, no. 3 (March 2003): 524–28. https://doi.org/10.3171/jns.2003.98.3.0524.
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    • Liao, Lawrence, and David F. Kong. “Angiographic changes in vein grafts: stable surrogate or seductive siren?” Am Heart J 145, no. 2 (February 2003): 187–89. https://doi.org/10.1067/mhj.2003.114.
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    • Kandzari, David E., Joseph Kay, J Conor O’Shea, Benjamin H. Trichon, Mark Donahue, Lawrence Liao, and Sunil V. Rao. “Highlights from the American Heart Association annual scientific sessions 2001: November 11 to 14, 2001.” Am Heart J 143, no. 2 (February 2002): 217–28. https://doi.org/10.1067/mhj.2002.121794.
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    • Liao, L., J. G. Jollis, E. R. DeLong, E. D. Peterson, K. G. Morris, and D. B. Mark. “Impact of an interactive video on decision making of patients with ischemic heart disease.” J Gen Intern Med 11, no. 6 (June 1996): 373–76. https://doi.org/10.1007/BF02600051.
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    • JOLLIS, J. G., E. R. DELONG, S. R. COLLINS, L. H. MUHLBAIER, L. LIAO, and D. B. MARK. “SURVIVAL FOLLOWING ACUTE MYOCARDIAL-INFARCTION ACCORDING TO PHYSICIAN SPECIALTY.” Circulation 92, no. 8 (October 15, 1995): 564–564.
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  • Conference Papers

    • Rao, Sunil V., Padma Kaul, Lawrence Liao, Daniel B. Mark, Eric L. Eisenstein, Paul W. Armstrong, Magnus Ohman, Christopher B. Granger, Robert M. Califf, and Robert A. Harrington. “Bleeding complications are a major driver of resource use among patients with acute coronary syndromes.” In Journal of the American College of Cardiology, 49:252A-252A. ELSEVIER SCIENCE INC, 2007.
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    • Liao, L., D. F. Kong, Z. Samad, P. A. Pappas, J. G. Jollis, S. S. Lin, A. Wang, et al. “Echocardiographic risk-stratification for early surgery in patients with endocarditis is a cost-attractive alternative to standard care.” In Journal of the American College of Cardiology, 47:280A-280A. ELSEVIER SCIENCE INC, 2006.
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    • Liao, L., J. H. Alexander, D. F. Kong, M. H. Sketch, P. A. Pappas, J. Zhou, S. S. Lin, L. K. Shaw, K. J. Anstrom, and D. B. Mark. “Which patients with previous bypass surgery benefit most from repeat revascularization?” In Journal of the American College of Cardiology, 47:203A-203A. ELSEVIER SCIENCE INC, 2006.
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    • Liao, L., A. Sarria-Santamera, A. Huntington, D. J. Whellan, D. B. Matchar, and D. F. Kong. “Meta-analysis of survival and angina relief after transmyocardial revascularization.” In Journal of the American College of Cardiology, 45:357A-357A. ELSEVIER SCIENCE INC, 2005.
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    • Liao, L., J. G. Jollis, D. J. Whellan, A. Chen, K. J. Anstrom, D. W. Kitzman, G. P. Aurigemma, K. A. Schulman, and J. S. Gottdiener. “Differences in health care costs for systolic versus diastolic heart failure of the elderly: The cardiovascular health study.” In Circulation, 108:775–775. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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    • Liao, L., J. S. Gottdiener, D. J. Whellan, A. Chen, K. J. Anstrom, D. W. Kitzman, G. P. Aurigemma, K. A. Schulman, and J. G. Jollis. “Total 4-year health care costs and resource use in elderly patients with congestive heart failure: The cardiovascular health study.” In Circulation, 108:756–756. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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    • Kaul, P., L. Davidson-Ray, P. Cowper, L. Liao, and D. Mark. “Economic burden of nonischemic congestive heart failure: Evidence from PRAISE-2.” In Journal of the American College of Cardiology, 41:535A-535A. ELSEVIER SCIENCE INC, 2003.
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    • Liao, L., J. G. Jollis, W. T. Smith, E. J. Velazquez, T. Ryan, T. S. Kisslo, and C. K. Landolfo. “Myocardial viability predicts long-term survival for patients with severe left ventricular dysfunction.” In Journal of the American College of Cardiology, 41:426A-426A. ELSEVIER SCIENCE INC, 2003.
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    • Liao, L., M. K. Bundorf, K. A. Schulman, D. J. Whellan, D. B. Mark, and J. G. Jollis. “Patient, hospital, physician, and market correlates of one-year costs after acute myocardial infarction in the elderly.” In Journal of the American College of Cardiology, 41:540A-540A. ELSEVIER SCIENCE INC, 2003.
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    • Liao, L., D. F. Kong, L. K. Shaw, M. H. Sketch, C. A. Milano, and D. B. Mark. “A statistical tool for predicting survival after bypass surgery: The Duke graft index.” In Circulation, 106:413–413. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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    • Liao, L., D. B. Mark, and J. G. Joilis. “Does an educational intervention influence patient decision making? Impact of an interactive video on ischemic heart disease patients.” In Journal of the American College of Cardiology, 39:449A-450A. ELSEVIER SCIENCE INC, 2002.
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