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Jeffrey Harold Lawson

Adjunct Professor in the Department of Surgery
Surgery, Vascular and Endovascular Surgery
Box 2622 Med Ctr, Durham, NC
481 Med Sci Res Bldg, Durham, NC

Overview


The research interests of my laboratory include the study of vascular biology and cellular differentiation of vascular tissue, the proteolytic and cell mediated regulation of blood coagulation, inflammatory mediated thrombosis, and the development of bioengineered blood vessels. The clinical interests of my laboratory include the study of novel therapies for vascular and cardiovascular surgery, thrombosis related to surgical procedures, clinical inhibitors of blood coagulation proteases, and the study of the immune response to biologics used in surgery.

Current Appointments & Affiliations


Adjunct Professor in the Department of Surgery · 2018 - Present Surgery, Vascular and Endovascular Surgery, Surgery

In the News


Published March 15, 2017
Growing Medical Device Company InnAVasc Could Reduce Dialysis Complications
Published May 17, 2016
Lab-grown blood vessels appear a safe alternative to synthetic implants
Published May 12, 2016
Bioengineered Blood Vessel Appears Safe for Dialysis Patients

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Recent Publications


Piezo-type mechanosensitive ion channel component 1 (PIEZO1) is upregulated in peripheral arterial disease (PAD) and a novel murine PAD model.

Journal Article JVS Vasc Sci · 2025 OBJECTIVE: The objectives of this work are to: define murine femoral artery stiffening with age and the modifiability of this process by exercise; impose peripheral arterial disease (PAD) hemodynamics on murine femoral arteries and to deliver focal atheros ... Full text Link to item Cite

Hemodialysis Reliable Outflow (HeRO) graft creation in upper extremities abandoned due to stent obstruction via recanalization and HeRO outflow component insertion across stent interstices.

Journal Article J Vasc Access · September 2023 BACKGROUND: The purpose of this study was to assess the feasibility and outcomes of recanalization and subsequent HeRO graft outflow component insertion across stent interstices in patients with an otherwise abandoned upper extremity. METHODS: Over a 10-ye ... Full text Link to item Cite

Evaluation of tissue-engineered human acellular vessels as a Blalock-Taussig-Thomas shunt in a juvenile primate model.

Journal Article JTCVS Open · September 2023 OBJECTIVES: Palliative treatment of cyanotic congenital heart disease (CCHD) uses systemic-to-pulmonary conduits, often a modified Blalock-Taussig-Thomas shunt (mBTTs). Expanded polytetrafluoroethylene (ePTFE) mBTTs have associated risks for thrombosis and ... Full text Link to item Cite
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Recent Grants


Skeletal Muscle and Vascular Remodeling in Peripheral Artery Disease

ResearchCollaborator · Awarded by National Institutes of Health · 2015 - 2018

Exercise, Nitric Oxide Bioavailability and Arteriovenous Fistula Maturation

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2017

HeRO Graft Registry Protocol

Clinical TrialPrincipal Investigator · Awarded by CryoLife · 2014 - 2017

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Education, Training & Certifications


University of Vermont · 1992 Ph.D.
University of Vermont · 1991 M.D.