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Overview


Dr. Vajzovic is a vitreoretinal surgeon and tenured Professor of Ophthalmology at Duke University School of Medicine with expertise in adult and pediatric retinal diseases and surgery. 

Dr. Vajzovic is passionate about translational research and collaborates closely with Duke biomedical engineers to develop imaging devices to improve ophthalmic care.  She serves as a principal investigator for numerous national clinical trials in early to late stages of development.  Her research interests span from pediatric retinal diseases such as retinopathy of prematurity to adult diseases such as age-related macular degeneration, diabetic retinopathy and venous occlusive diseases, as well as vitreoretinal surgical topics such as retinal tears, retinal detachments, macular holes and macular puckers.

In addition, Dr. Vajzovic is interested in cutting edge technologies and recovery of vision in hereditary and common retinal diseases with gene-therapy, stem cell technology and retinal implants. She is a co-director of the Duke Pediatric Retina and Optic Nerve Center, and directs the Duke Center for Artificial and Regenerative Vision, where she performs gene-therapy delivery, and implantation of the Argus II “bionic eye” to restore vision to individuals with total blindness.

An influential educator, she organizes and directs several highly successful national and international courses, including the first-of-its-kind Advances in Pediatric Retina Course at Duke and the international Duke Fellows Advances in Vitreous Surgery Course. She is director of prestigious Duke Vitreoretinal Surgical Fellowship and director of Duke Eye Center’s Continuing Medical Education program.

Dr. Vajzovic completed her vitreoretinal fellowship training at Duke and residency training at Bascom Palmer Eye Institute in Miami, FL.  While in training, she received Heed Fellowship Award, Society of Heed Fellows Award and Retina Society Research Award. She is active on the Women in Ophthalmology Board of Directors where she serves as a Treasurer and a Chair of Clinical Trial Training Program.  In addition, she serves as a Retina Society AAO Council Representative.  She is elected member of the Retina Society, Macula Society and Club Jules Gonin Society.  Dr. Vajzovic has been awarded the American Academy of Ophthalmology Achievement Award, American Society of Retina Specialists Senior Honor Award, Women in Ophthalmology Emerging Leader Award and Emerging Leader Award by Duke University School of Medicine and Duke Medical Alumni Association.

Current Appointments & Affiliations


Professor of Ophthalmology · 2024 - Present Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology
Director of CME - Ophthalmology · 2017 - Present Ophthalmology, Clinical Science Departments

In the News


Published November 2, 2025
Preserving Sight With a Gene Therapy Implant
Published May 31, 2021
2020 Emerging Leader Lejla Vajzovic, MD, HS’11-’13

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Recent Publications


Approach to Ophthalmic Surgery Involving the Anterior Vitreous: A Clinical Practice Update from the American Society of Retina Specialists

Journal Article Journal of Vitreoretinal Diseases · November 1, 2025 When encountering diseases of the anterior vitreous and peripheral retina (ie, the “middle segment” of the eye), vitreoretinal (VR) surgeons are specifically trained in surgical techniques for managing the vitreous and visualizing the peripheral retina dur ... Full text Cite

Novel artificial intelligence applications for pediatric retina.

Journal Article Curr Opin Ophthalmol · September 19, 2025 PURPOSE OF REVIEW: This review examines the emerging role of artificial intelligence (AI) in the detection and management of pediatric retinal diseases, with a focus on systems that achieve expert-level performance in classifying fundus abnormalities. We h ... Full text Link to item Cite

Effect of Faricimab on Visual Acuity and Retinal Structure in Neovascular Age-Related Macular Degeneration Previously Treated With Anti-VEGF Therapy.

Journal Article J Vitreoretin Dis · August 30, 2025 Purpose: To evaluate the effects of switching from traditional antivascular endothelial growth factor (anti-VEGF) therapies to faricimab, a biclonal antibody that targets both VEGF and angiopoietin-2, on eyes with neovascular age-related macular degenerati ... Full text Link to item Cite
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Education, Training & Certifications


Mayo Clinic, Alix School of Medicine · 2006 M.D.
University of Missouri, Columbia · 2002 B.S.