Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • P.T., Yokohama City University (Japan) 1999
  • M.D., Norman Bethune University of Medical Sciences (China) 1988
• 

  Previous Appointments & Affiliations

  • Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2015 - 2021
  • Member of the Center for Brain Imaging and Analysis, Duke-UNC Center for Brain Imaging and Analysis, Institutes and Centers 2006 - 2020
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2007 - 2014
• Research
• 

  Selected Grants

  • 2/2 Phenotype-Genotype Predictors of Cognitive Outcomes in Geriatric Depression awarded by National Institutes of Health 2020 - 2022
  • Dorsal Cingulate Activity and Cognitive Decline in Late-Life Depression awarded by National Institutes of Health 2012 - 2018
  • Prefrontal Function in Adolescent Limited vs Life Course Persistent SUD awarded by National Institutes of Health 2008 - 2014
  • Neuroimaging of Nicotine Dependence, Depression and Emotion Regulation awarded by National Institutes of Health 2012 - 2013
  • Geriatric Depression: Risk Factors for Adverse Outcomes awarded by National Institutes of Health 1995 - 2012
  • FMRI: Prediction of Mild Cognitive Impairment in Geriatric Depression awarded by National Institutes of Health 2008 - 2012
  • A Linux Cluster Computational Facility for Neuroimaging Research awarded by National Institutes of Health 2009 - 2010
• 

  External Relationships

  • Beijing Hospital of Traditional Chinese Medicine
  • University of Connecticut Health Center
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Steffens, David C., Mario Fahed, Kevin J. Manning, and Lihong Wang. “The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research.” Transl Psychiatry 12, no. 1 (December 26, 2022): 525. https://doi.org/10.1038/s41398-022-02292-3.
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    • Zhang, Zhu-Qing, Zhi-Peng Guo, Xue-Yu Lv, Peter Sörös, Xiao-Xu Wang, Lihong Wang, and Chun-Hong Liu. “Effect and neural mechanisms of the transcutaneous vagus nerve stimulation for relapse prevention in patients with remitted major depressive disorder: protocol for a longitudinal study.” Bmj Open 12, no. 2 (February 22, 2022): e050446. https://doi.org/10.1136/bmjopen-2021-050446.
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    • Manning, Kevin J., Joshua Preciado-Pina, Lihong Wang, Kimberly Fitzgibbon, Grace Chan, and David C. Steffens. “Cognitive variability, brain aging, and cognitive decline in late-life major depression.” Int J Geriatr Psychiatry 36, no. 5 (May 2021): 665–76. https://doi.org/10.1002/gps.5465.
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    • Joseph, Chinaka, Lihong Wang, Rong Wu, Kevin J. Manning, and David C. Steffens. “Structural brain changes and neuroticism in late-life depression: a neural basis for depression subtypes.” Int Psychogeriatr 33, no. 5 (May 2021): 515–20. https://doi.org/10.1017/S1041610221000284.
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    • Steffens, David C., Lihong Wang, and Godfrey D. Pearlson. “Functional connectivity predictors of acute depression treatment outcome.” Int Psychogeriatr 31, no. 12 (December 2019): 1831–35. https://doi.org/10.1017/S1041610218002260.
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    • Zou, Dongfang, Feiqiu Wen, Hongwu Zeng, Huirong Mai, Xiuli Yuan, Lihong Wang, Yue Li, Liwei Liu, Sixi Liu, and Guosheng Liu. “Improving brain function of pediatric acute lymphoblastic leukemia patients after induction chemotherapy, a pilot self-contrast study by fractional amplitude of low-frequency fluctuation.” J Clin Neurosci 66 (August 2019): 149–55. https://doi.org/10.1016/j.jocn.2019.04.033.
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    • Zhang, Xue, Scott A. Huettel, O’Dhaniel A. Mullette-Gillman, Hua Guo, and Lihong Wang. “Exploring common changes after acute mental stress and acute tryptophan depletion: Resting-state fMRI studies.” J Psychiatr Res 113 (June 2019): 172–80. https://doi.org/10.1016/j.jpsychires.2019.03.025.
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    • Liu, Chun-Hong, Li-Rong Tang, Yue Gao, Guang-Zhong Zhang, Bin Li, Meng Li, Marie Woelfer, Walter Martin, and Lihong Wang. “Resting-state mapping of neural signatures of vulnerability to depression relapse.” J Affect Disord 250 (May 1, 2019): 371–79. https://doi.org/10.1016/j.jad.2019.03.022.
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    • Emam, Hadeer, David C. Steffens, Godfrey D. Pearlson, and Lihong Wang. “Increased ventromedial prefrontal cortex activity and connectivity predict poor sertraline treatment outcome in late-life depression.” Int J Geriatr Psychiatry 34, no. 5 (May 2019): 730–37. https://doi.org/10.1002/gps.5079.
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    • Liu, Chun-Hong, Guang-Zhong Zhang, Bin Li, Meng Li, Marie Woelfer, Martin Walter, and Lihong Wang. “Role of inflammation in depression relapse.” J Neuroinflammation 16, no. 1 (April 17, 2019): 90. https://doi.org/10.1186/s12974-019-1475-7.
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    • Manning, Kevin, Lihong Wang, and David Steffens. “Recent advances in the use of imaging in psychiatry: functional magnetic resonance imaging of large-scale brain networks in late-life depression.” F1000res 8 (2019). https://doi.org/10.12688/f1000research.17399.1.
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    • Ji, Lanxin, Godfrey D. Pearlson, Xue Zhang, David C. Steffens, Xiaoqing Ji, Hua Guo, and Lihong Wang. “Physical exercise increases involvement of motor networks as a compensatory mechanism during a cognitively challenging task.” Int J Geriatr Psychiatry 33, no. 8 (August 2018): 1153–59. https://doi.org/10.1002/gps.4909.
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    • Liu, C. H., J. Guo, S. L. Lu, L. R. Tang, J. Fan, C. Y. Wang, L. Wang, Q. Q. Liu, and C. Z. Liu. “Increased salience network activity in patients with insomnia complaints in major depressive disorder.” Frontiers in Psychiatry 9, no. MAR (March 20, 2018). https://doi.org/10.3389/fpsyt.2018.00093.
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    • Ji, L., G. D. Pearlson, K. A. Hawkins, D. C. Steffens, H. Guo, and L. Wang. “A new measure for neural compensation is positively correlated with working memory and gait speed.” Frontiers in Aging Neuroscience 10, no. MAR (March 19, 2018). https://doi.org/10.3389/fnagi.2018.00071.
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    • Li, Xuesong, Xiaodong Ma, Lyu Li, Zhe Zhang, Xue Zhang, Yan Tong, Lihong Wang, Lihong Sen Song, and Hua Guo. “Dual-TRACER: High resolution fMRI with constrained evolution reconstruction.” Neuroimage 164 (January 1, 2018): 172–82. https://doi.org/10.1016/j.neuroimage.2017.02.087.
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    • Hu, Zhanqi, Dongfang Zou, Huirong Mai, Xiuli Yuan, Lihong Wang, Yue Li, Jianxiang Liao, et al. “Altered brain function in new onset childhood acute lymphoblastic leukemia before chemotherapy: A resting-state fMRI study.” Brain Dev 39, no. 9 (October 2017): 743–50. https://doi.org/10.1016/j.braindev.2017.04.014.
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    • Steffens, David C., Lihong Wang, Kevin J. Manning, and Godfrey D. Pearlson. “Negative Affectivity, Aging, and Depression: Results From the Neurobiology of Late-Life Depression (NBOLD) Study.” Am J Geriatr Psychiatry 25, no. 10 (October 2017): 1135–49. https://doi.org/10.1016/j.jagp.2017.03.017.
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    • Siciliano, Rachel E., David J. Madden, Catherine W. Tallman, Maria A. Boylan, Imke Kirste, Zachary A. Monge, Lauren E. Packard, Guy G. Potter, and Lihong Wang. “Task difficulty modulates brain activation in the emotional oddball task.” Brain Res 1664 (June 1, 2017): 74–86. https://doi.org/10.1016/j.brainres.2017.03.028.
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    • Liu, Chun-Hong, Xin Ma, Zhen Yuan, Lu-Ping Song, Bing Jing, Hong-Yu Lu, Li-Rong Tang, et al. “Decreased Resting-State Activity in the Precuneus Is Associated With Depressive Episodes in Recurrent Depression.” J Clin Psychiatry 78, no. 4 (April 2017): e372–82. https://doi.org/10.4088/JCP.15m10022.
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    • Li, Xuesong, David C. Steffens, Guy G. Potter, Hua Guo, Sen Song, and Lihong Wang. “Decreased between-hemisphere connectivity strength and network efficiency in geriatric depression.” Hum Brain Mapp 38, no. 1 (January 2017): 53–67. https://doi.org/10.1002/hbm.23343.
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    • Chou, Ying-Hui, Mark Sundman, Heather E. Whitson, Pooja Gaur, Mei-Lan Chu, Carol P. Weingarten, David J. Madden, et al. “Maintenance and Representation of Mind Wandering during Resting-State fMRI.” Scientific Reports 7 (January 2017): 40722. https://doi.org/10.1038/srep40722.
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    • Ji, Lanxin, Han Zhang, Guy G. Potter, Yu-Feng Zang, David C. Steffens, Hua Guo, and Lihong Wang. “Multiple Neuroimaging Measures for Examining Exercise-induced Neuroplasticity in Older Adults: A Quasi-experimental Study.” Front Aging Neurosci 9 (2017): 102. https://doi.org/10.3389/fnagi.2017.00102.
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    • Zhao, Y., X. Zhao, L. Wang, Y. Chen, and X. Zhang. “Does elicitation method matter? Behavioral and neuroimaging evidence from capacity allocation game.” Production and Operations Management 25, no. 5 (May 1, 2016): 919–34. https://doi.org/10.1111/poms.12515.
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    • Zou, Dong-Fang, Hong-Wu Zeng, Jie Yu, Hui-Rong Mai, Xiu-Li Yuan, Li-Hong Wang, Jian-Xiang Liao, and Fei-Qiu Wen. “[Brain injury after induction chemotherapy in children with acute lymphoblastic leukemia].” Zhongguo Dang Dai Er Ke Za Zhi 18, no. 3 (March 2016): 254–58. https://doi.org/10.7499/j.issn.1008-8830.2016.03.013.
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    • Ou, Jinli, Li Xie, Xiang Li, Dajiang Zhu, Douglas P. Terry, A Nicholas Puente, Rongxin Jiang, et al. “Atomic connectomics signatures for characterization and differentiation of mild cognitive impairment.” Brain Imaging Behav 9, no. 4 (December 2015): 663–77. https://doi.org/10.1007/s11682-014-9320-1.
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    • Liu, Wei, HuiJuan Liu, Dongtao Wei, Jiangzhou Sun, Junyi Yang, Jie Meng, Lihong Wang, and Jiang Qiu. “Abnormal degree centrality of functional hubs associated with negative coping in older Chinese adults who lost their only child.” Biol Psychol 112 (December 2015): 46–55. https://doi.org/10.1016/j.biopsycho.2015.09.005.
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    • Liu, Chun-Hong, Xin Ma, Lu-Ping Song, Jin Fan, Wei-Dong Wang, Xue-Yu Lv, Yu Zhang, Feng Li, Lihong Wang, and Chuan-Yue Wang. “Abnormal spontaneous neural activity in the anterior insular and anterior cingulate cortices in anxious depression.” Behav Brain Res 281 (March 15, 2015): 339–47. https://doi.org/10.1016/j.bbr.2014.11.047.
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    • Wang, Lihong, Ying-Hui Chou, Guy G. Potter, and David C. Steffens. “Altered Synchronizations among Neural Networks in Geriatric Depression.” Biomed Res Int 2015 (2015): 343720. https://doi.org/10.1155/2015/343720.
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    • Jiang, Xi, Dajiang Zhu, Kaiming Li, Tuo Zhang, Lihong Wang, Dinggang Shen, Lei Guo, and Tianming Liu. “Predictive models of resting state networks for assessment of altered functional connectivity in mild cognitive impairment.” Brain Imaging Behav 8, no. 4 (December 2014): 542–57. https://doi.org/10.1007/s11682-013-9280-x.
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    • Zhu, Dajiang, Kaiming Li, Douglas P. Terry, A Nicholas Puente, Lihong Wang, Dinggang Shen, L Stephen Miller, and Tianming Liu. “Connectome-scale assessments of structural and functional connectivity in MCI.” Hum Brain Mapp 35, no. 7 (July 2014): 2911–23. https://doi.org/10.1002/hbm.22373.
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    • Crozier, Joseph C., Lihong Wang, Scott A. Huettel, and Michael D. De Bellis. “Neural correlates of cognitive and affective processing in maltreated youth with posttraumatic stress symptoms: does gender matter?” Dev Psychopathol 26, no. 2 (May 2014): 491–513. https://doi.org/10.1017/S095457941400008X.
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    • Wang, Zicong, Sen Song, and Lihong Wang. “[The impact of mood on the intrinsic functional connectivity].” Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 31, no. 2 (April 2014): 262–66.
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    • Wee, Chong-Yaw, Pew-Thian Yap, Daoqiang Zhang, Lihong Wang, and Dinggang Shen. “Group-constrained sparse fMRI connectivity modeling for mild cognitive impairment identification.” Brain Struct Funct 219, no. 2 (March 2014): 641–56. https://doi.org/10.1007/s00429-013-0524-8.
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    • Dolcos, Florin, Lihong Wang, and Mara Mather. “Current research and emerging directions in emotion-cognition interactions.” Front Integr Neurosci 8 (2014): 83. https://doi.org/10.3389/fnint.2014.00083.
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    • De Bellis, Michael D., Lihong Wang, Sara R. Bergman, Richard H. Yaxley, Stephen R. Hooper, and Scott A. Huettel. “Neural mechanisms of risky decision-making and reward response in adolescent onset cannabis use disorder.” Drug Alcohol Depend 133, no. 1 (November 1, 2013): 134–45. https://doi.org/10.1016/j.drugalcdep.2013.05.020.
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    • Winecoff, Amy, John A. Clithero, R McKell Carter, Sara R. Bergman, Lihong Wang, and Scott A. Huettel. “Ventromedial prefrontal cortex encodes emotional value.” J Neurosci 33, no. 27 (July 3, 2013): 11032–39. https://doi.org/10.1523/JNEUROSCI.4317-12.2013.
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    • Hu, Xintao, Dajiang Zhu, Peili Lv, Kaiming Li, Junwei Han, Lihong Wang, Dinggang Shen, Lei Guo, and Tianming Liu. “Fine-granularity functional interaction signatures for characterization of brain conditions.” Neuroinformatics 11, no. 3 (July 2013): 301–17. https://doi.org/10.1007/s12021-013-9177-2.
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    • Zhu, Dajiang, Kaiming Li, Lei Guo, Xi Jiang, Tuo Zhang, Degang Zhang, Hanbo Chen, et al. “DICCCOL: dense individualized and common connectivity-based cortical landmarks.” Cereb Cortex 23, no. 4 (April 2013): 786–800. https://doi.org/10.1093/cercor/bhs072.
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    • Froeliger, Brett, Leslie A. Modlin, Rachel V. Kozink, Lihong Wang, Eric L. Garland, Merideth A. Addicott, and F Joseph McClernon. “Frontoparietal attentional network activation differs between smokers and nonsmokers during affective cognition.” Psychiatry Res 211, no. 1 (January 30, 2013): 57–63. https://doi.org/10.1016/j.pscychresns.2012.05.002.
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    • Wang, Li, Feng Shi, Gang Li, Weili Lin, John H. Gilmore, and Dinggang Shen. “Integration of sparse multi-modality representation and geometrical constraint for isointense infant brain segmentation.” Med Image Comput Comput Assist Interv 16, no. Pt 1 (2013): 703–10. https://doi.org/10.1007/978-3-642-40811-3_88.
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    • Wang, Li, Ken Chung Chen, Feng Shi, Shu Liao, Gang Li, Yaozong Gao, Steve G. F. Shen, et al. “Automated segmentation of CBCT image using spiral CT atlases and convex optimization.” Med Image Comput Comput Assist Interv 16, no. Pt 3 (2013): 251–58. https://doi.org/10.1007/978-3-642-40760-4_32.
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    • Wang, Lihong, Natalie Paul, Steve J. Stanton, Jeffrey M. Greeson, and Moria J. Smoski. “Loss of sustained activity in the ventromedial prefrontal cortex in response to repeated stress in individuals with early-life emotional abuse: implications for depression vulnerability.” Front Psychol 4 (2013): 320. https://doi.org/10.3389/fpsyg.2013.00320.
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    • Wee, C. -. Y., P. -. T. Yap, D. Zhang, L. Wang, and D. Shen. “Group-constrained sparse fMRI connectivity modeling for mild cognitive impairment identification.” Brain Structure and Function, 2013, 1–16.
    • Li, Gang, Li Wang, Feng Shi, Weili Lin, and Dinggang Shen. “Multi-atlas based simultaneous labeling of longitudinal dynamic cortical surfaces in infants.” Med Image Comput Comput Assist Interv 16, no. Pt 1 (2013): 58–65. https://doi.org/10.1007/978-3-642-40811-3_8.
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    • Paul, Natalie A., Steven J. Stanton, Jeffrey M. Greeson, Moria J. Smoski, and Lihong Wang. “Psychological and neural mechanisms of trait mindfulness in reducing depression vulnerability.” Soc Cogn Affect Neurosci 8, no. 1 (January 2013): 56–64. https://doi.org/10.1093/scan/nss070.
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    • Shi, Feng, Jian Cheng, Li Wang, Pew-Thian Yap, and Dinggang Shen. “Low-rank total variation for image super-resolution.” Med Image Comput Comput Assist Interv 16, no. Pt 1 (2013): 155–62. https://doi.org/10.1007/978-3-642-40811-3_20.
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    • Singhal, A., A. T. Shafer, M. Russell, B. Gibson, L. Wang, S. Vohra, and F. Dolcos. “Electrophysiological correlates of fearful and sad distraction on target processing in adolescents with attention deficit-hyperactivity symptoms and affective disorders.” Frontiers in Integrative Neuroscience, no. NOV (November 30, 2012). https://doi.org/10.3389/fnint.2012.00119.
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    • Wang, Lihong, Guy G. Potter, RK Ranga Krishnan, Florin Dolcos, Gwenn S. Smith, and David C. Steffens. “Neural correlates associated with cognitive decline in late-life depression.” Am J Geriatr Psychiatry 20, no. 8 (August 2012): 653–63. https://doi.org/10.1097/JGP.0b013e31823e2cc7.
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    • Froeliger, Brett, Leslie A. Modlin, Rachel V. Kozink, Lihong Wang, and F Joseph McClernon. “Smoking abstinence and depressive symptoms modulate the executive control system during emotional information processing.” Addict Biol 17, no. 3 (May 2012): 668–79. https://doi.org/10.1111/j.1369-1600.2011.00410.x.
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    • Wang, L., A. Ashley-Koch, D. C. Steffens, K. R. R. Krishnan, and W. D. Taylor. “Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function.” Genes Brain Behav 11, no. 3 (April 2012): 352–59. https://doi.org/10.1111/j.1601-183X.2012.00764.x.
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    • Froeliger, Brett, Leslie Modlin, Lihong Wang, Rachel V. Kozink, and F Joseph McClernon. “Nicotine withdrawal modulates frontal brain function during an affective Stroop task.” Psychopharmacology (Berl) 220, no. 4 (April 2012): 707–18. https://doi.org/10.1007/s00213-011-2522-y.
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    • Wong, Gloria, Sanda Dolcos, Ekaterina Denkova, Rajendra Morey, Lihong Wang, Gregory McCarthy, and Florin Dolcos. “Brain imaging investigation of the impairing effect of emotion on cognition.” J Vis Exp, no. 60 (February 1, 2012). https://doi.org/10.3791/2434.
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    • Wee, Chong-Yaw, Pew-Thian Yap, Daoqiang Zhang, Kevin Denny, Jeffrey N. Browndyke, Guy G. Potter, Kathleen A. Welsh-Bohmer, Lihong Wang, and Dinggang Shen. “Identification of MCI individuals using structural and functional connectivity networks.” Neuroimage 59, no. 3 (February 1, 2012): 2045–56. https://doi.org/10.1016/j.neuroimage.2011.10.015.
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    • Shi, Feng, Li Wang, Guorong Wu, Yu Zhang, Manhua Liu, John H. Gilmore, Weili Lin, and Dinggang Shen. “Atlas construction via dictionary learning and group sparsity.” Med Image Comput Comput Assist Interv 15, no. Pt 1 (2012): 247–55. https://doi.org/10.1007/978-3-642-33415-3_31.
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    • Singhal, A., A. T. Shafer, M. Russell, B. Gibson, L. Wang, S. Vohra, and F. Dolcos. “Electrophysiological correlates of fearful and sad distraction on target processing in adolescents with attention deficit-hyperactivity symptoms and affective disorders.” Frontiers in Integrative Neuroscience, no. DEC (2012).
    • Wee, C. Y., P. T. Yap, D. Zhang, L. Wang, and D. Shen. “Constrained sparse functional connectivity networks for MCI classification.” Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 7511 LNCS (January 1, 2012): 212–19.
    • Wee, Chong-Yaw, Pew-Thian Yap, Daoqiang Zhang, Lihong Wang, and Dinggang Shen. “Constrained sparse functional connectivity networks for MCI classification.” Med Image Comput Comput Assist Interv 15, no. Pt 2 (2012): 212–19. https://doi.org/10.1007/978-3-642-33418-4_27.
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    • Wee, Chong-Yaw, Pew-Thian Yap, Kevin Denny, Jeffrey N. Browndyke, Guy G. Potter, Kathleen A. Welsh-Bohmer, Lihong Wang, and Dinggang Shen. “Resting-state multi-spectrum functional connectivity networks for identification of MCI patients.” Plos One 7, no. 5 (2012): e37828. https://doi.org/10.1371/journal.pone.0037828.
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    • Layous, Kristin, Joseph Chancellor, Sonja Lyubomirsky, Lihong Wang, and P Murali Doraiswamy. “Delivering happiness: translating positive psychology intervention research for treating major and minor depressive disorders.” J Altern Complement Med 17, no. 8 (August 2011): 675–83. https://doi.org/10.1089/acm.2011.0139.
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    • Smoski, Moria J., Nicholas Salsman, Lihong Wang, Veronica Smith, Thomas R. Lynch, Stephen R. Dager, Kevin S. LaBar, and Marsha M. Linehan. “Functional imaging of emotion reactivity in opiate-dependent borderline personality disorder.” Personal Disord 2, no. 3 (July 2011): 230–41. https://doi.org/10.1037/a0022228.
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    • Wee, Chong-Yaw, Pew-Thian Yap, Wenbin Li, Kevin Denny, Jeffrey N. Browndyke, Guy G. Potter, Kathleen A. Welsh-Bohmer, Lihong Wang, and Dinggang Shen. “Enriched white matter connectivity networks for accurate identification of MCI patients.” Neuroimage 54, no. 3 (February 1, 2011): 1812–22. https://doi.org/10.1016/j.neuroimage.2010.10.026.
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    • Alalade, Emmanuel, Kevin Denny, Guy Potter, David Steffens, and Lihong Wang. “Altered cerebellar-cerebral functional connectivity in geriatric depression.” Plos One 6, no. 5 (2011): e20035. https://doi.org/10.1371/journal.pone.0020035.
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    • Shi, Feng, Li Wang, John H. Gilmore, Weili Lin, and Dinggang Shen. “Learning-based meta-algorithm for MRI brain extraction.” Med Image Comput Comput Assist Interv 14, no. Pt 3 (2011): 313–21. https://doi.org/10.1007/978-3-642-23626-6_39.
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    • Steffens, David C., Warren D. Taylor, Kevin L. Denny, Sara R. Bergman, and Lihong Wang. “Structural integrity of the uncinate fasciculus and resting state functional connectivity of the ventral prefrontal cortex in late life depression.” Plos One 6, no. 7 (2011): e22697. https://doi.org/10.1371/journal.pone.0022697.
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    • Wee, Chong-Yaw, Pew-Thian Yap, Daoqiang Zhang, Kevin Denny, Lihong Wang, and Dinggang Shen. “Identification of individuals with MCI via multimodality connectivity networks.” Med Image Comput Comput Assist Interv 14, no. Pt 2 (2011): 277–84. https://doi.org/10.1007/978-3-642-23629-7_34.
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    • Denkova, Ekaterina, Gloria Wong, Sanda Dolcos, Keen Sung, Lihong Wang, Nicholas Coupland, and Florin Dolcos. “The impact of anxiety-inducing distraction on cognitive performance: a combined brain imaging and personality investigation.” Plos One 5, no. 11 (November 30, 2010): e14150. https://doi.org/10.1371/journal.pone.0014150.
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    • Morey, Rajendra A., Elizabeth S. Selgrade, Henry Ryan Wagner, Scott A. Huettel, Lihong Wang, and Gregory McCarthy. “Scan-rescan reliability of subcortical brain volumes derived from automated segmentation.” Hum Brain Mapp 31, no. 11 (November 2010): 1751–62. https://doi.org/10.1002/hbm.20973.
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    • Wee, C. Y., P. T. Yap, J. N. Brownyke, G. G. Potter, D. C. Steffens, K. Welsh-Bohmer, L. Wang, and D. Shen. “Accurate identification of MCI patients via enriched white-matter connectivity network.” Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 6357 LNCS (October 25, 2010): 140–47. https://doi.org/10.1007/978-3-642-15948-0_18.
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    • Biswal, Bharat B., Maarten Mennes, Xi-Nian Zuo, Suril Gohel, Clare Kelly, Steve M. Smith, Christian F. Beckmann, et al. “Toward discovery science of human brain function.” Proc Natl Acad Sci U S A 107, no. 10 (March 9, 2010): 4734–39. https://doi.org/10.1073/pnas.0911855107.
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    • Wang, Lihong, O’Dhaniel A. Mullette-Gillman, Kishore M. Gadde, Cynthia M. Kuhn, Gregory McCarthy, and Scott A. Huettel. “The effect of acute tryptophan depletion on emotional distraction and subsequent memory.” Soc Cogn Affect Neurosci 4, no. 4 (December 2009): 357–68. https://doi.org/10.1093/scan/nsp025.
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    • Wang, L., F. C. Goldstein, E. Veledar, A. I. Levey, J. J. Lah, C. C. Meltzer, C. A. Holder, and H. Mao. “Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging.” Ajnr Am J Neuroradiol 30, no. 5 (May 2009): 893–99. https://doi.org/10.3174/ajnr.A1484.
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    • Wang, Lihong, Kevin S. LaBar, Moria Smoski, M Zachary Rosenthal, Florin Dolcos, Thomas R. Lynch, Ranga R. Krishnan, and Gregory McCarthy. “Prefrontal mechanisms for executive control over emotional distraction are altered in major depression.” Psychiatry Res 163, no. 2 (July 15, 2008): 143–55. https://doi.org/10.1016/j.pscychresns.2007.10.004.
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    • Wang, Lihong, K Ranga Krishnan, David C. Steffens, Guy G. Potter, Florin Dolcos, and Gregory McCarthy. “Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression.” Am J Psychiatry 165, no. 7 (July 2008): 863–71. https://doi.org/10.1176/appi.ajp.2008.07101590.
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    • Dolcos, Florin, Paul Diaz-Granados, Lihong Wang, and Gregory McCarthy. “Opposing influences of emotional and non-emotional distracters upon sustained prefrontal cortex activity during a delayed-response working memory task.” Neuropsychologia 46, no. 1 (January 15, 2008): 326–35. https://doi.org/10.1016/j.neuropsychologia.2007.07.010.
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    • Wang, Lihong, Scott Huettel, and Michael D. De Bellis. “Neural substrates for processing task-irrelevant sad images in adolescents.” Dev Sci 11, no. 1 (January 2008): 23–32. https://doi.org/10.1111/j.1467-7687.2007.00661.x.
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    • Petrella, Jeffrey R., Steven E. Prince, Lihong Wang, Caroline Hellegers, and P Murali Doraiswamy. “Prognostic value of posteromedial cortex deactivation in mild cognitive impairment.” Plos One 2, no. 10 (October 31, 2007): e1104. https://doi.org/10.1371/journal.pone.0001104.
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    • Petrella, Jeffrey R., Lihong Wang, Sriyesh Krishnan, Melissa J. Slavin, Steven E. Prince, Thanh-Thu T. Tran, and P Murali Doraiswamy. “Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging.” Radiology 245, no. 1 (October 2007): 224–35. https://doi.org/10.1148/radiol.2451061847.
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    • Robertson, Brigitte, Lihong Wang, Michele T. Diaz, Marilyn Aiello, Kenneth Gersing, John Beyer, Srinivasan Mukundan, Gregory McCarthy, and P Murali Doraiswamy. “Effect of bupropion extended release on negative emotion processing in major depressive disorder: a pilot functional magnetic resonance imaging study.” J Clin Psychiatry 68, no. 2 (February 2007): 261–67. https://doi.org/10.4088/jcp.v68n0212.
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    • Wang, Lihong, Kevin S. LaBar, and Gregory McCarthy. “Mood alters amygdala activation to sad distractors during an attentional task.” Biol Psychiatry 60, no. 10 (November 15, 2006): 1139–46. https://doi.org/10.1016/j.biopsych.2006.01.021.
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    • Dolcos, Florin, Philip Kragel, Lihong Wang, and Gregory McCarthy. “Role of the inferior frontal cortex in coping with distracting emotions.” Neuroreport 17, no. 15 (October 23, 2006): 1591–94. https://doi.org/10.1097/01.wnr.0000236860.24081.be.
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    • Li, Mei, Yoshiyuki Kuroiwa, Lihong Wang, Toshiaki Kamitani, Shu Omoto, Eiko Hayashi, Tatsuya Takahashi, et al. “Visual event-related potentials under different interstimulus intervals in Parkinson's disease: relation to motor disability, WAIS-R, and regional cerebral blood flow.” Parkinsonism Relat Disord 11, no. 4 (June 2005): 209–19. https://doi.org/10.1016/j.parkreldis.2004.11.004.
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    • Wang, Lihong, Gregory McCarthy, Allen W. Song, and Kevin S. Labar. “Amygdala activation to sad pictures during high-field (4 tesla) functional magnetic resonance imaging.” Emotion 5, no. 1 (March 2005): 12–22. https://doi.org/10.1037/1528-3542.5.1.12.
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    • Kamitani, Toshiaki, Yoshiyuki Kuroiwa, Lihong Wang, Mei Li, Tadashi Ikegami, and Sho Matsubara. “Event-related potentials during visual S1-S2 paradigm in multiple system atrophy: relation to morphologic changes on brain MRI measurement.” Parkinsonism Relat Disord 10, no. 2 (December 2003): 93–100. https://doi.org/10.1016/s1353-8020(03)00074-9.
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    • Wang, Lihong, Yoshiki Kaneoke, and Ryusuke Kakigi. “Spatiotemporal separability in the human cortical response to visual motion speed: a magnetoencephalography study.” Neurosci Res 47, no. 1 (September 2003): 109–16. https://doi.org/10.1016/s0168-0102(03)00191-3.
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    • Li, Mei, Yoshiyuki Kuroiwa, Lihong Wang, Toshiaki Kamitani, Tatsuya Takahashi, Yume Suzuki, and Shu Omoto. “Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study.” Parkinsonism Relat Disord 9, no. 6 (August 2003): 329–40. https://doi.org/10.1016/s1353-8020(02)00094-9.
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    • Kamitani, Toshiaki, Yoshiyuki Kuroiwa, Lihong Wang, Mei Li, Yume Suzuki, Tatsuya Takahashi, Tadashi Ikegami, and Sho Matsubara. “Visual event-related potential changes in two subtypes of multiple system atrophy, MSA-C and MSA-P.” J Neurol 249, no. 8 (August 2002): 975–82. https://doi.org/10.1007/s00415-002-0764-7.
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    • Wang, L., R. Kakigi, and M. Hoshiyama. “A magnetoencephalographic study on Wisconsin Card Sorting Test.” International Congress Series 1232, no. C (April 1, 2002): 535–41. https://doi.org/10.1016/S0531-5131(01)00833-0.
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    • Wang, L., C. Barber, R. Kakigi, Y. Kaneoke, T. Okusa, and Y. Wen. “A first comparison of the human multifocal visual evoked magnetic field and visual evoked potential.” Neurosci Lett 315, no. 1–2 (November 23, 2001): 13–16. https://doi.org/10.1016/s0304-3940(01)02302-3.
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    • Wang, L., R. Kakigi, and M. Hoshiyama. “Neural activities during Wisconsin Card Sorting Test--MEG observation.” Brain Res Cogn Brain Res 12, no. 1 (August 2001): 19–31. https://doi.org/10.1016/s0926-6410(01)00022-2.
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    • Wang, L., Y. Kuroiwa, M. Li, J. Wang, and T. Kamitani. “Do P1 and N1 evoked by the ERP task reflect primary visual processing in Parkinson's disease?” Doc Ophthalmol 102, no. 2 (March 2001): 83–93.
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    • Kondo, M., C. H. Piao, A. Tanikawa, M. Horiguchi, and Y. Miyake. “A contact lens electrode with built-in high intensity white light-emitting diodes. A contact lens electrode with built-in white LEDs.” Doc Ophthalmol 102, no. 1 (January 2001): 1–9.
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    • Wang, L., Y. Kuroiwa, T. Kamitani, M. Li, T. Takahashi, Y. Suzuki, M. Shimamura, and O. Hasegawa. “Visual event-related potentials in progressive supranuclear palsy, corticobasal degeneration, striatonigral degeneration, and Parkinson's disease.” J Neurol 247, no. 5 (May 2000): 356–63. https://doi.org/10.1007/s004150050602.
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    • Wang, L., Y. Kuroiwa, M. Li, T. Kamitani, J. Wang, T. Takahashi, Y. Suzuki, T. Ikegami, and S. Matsubara. “The correlation between P300 alterations and regional cerebral blood flow in non-demented Parkinson's disease.” Neurosci Lett 282, no. 3 (March 24, 2000): 133–36. https://doi.org/10.1016/s0304-3940(00)00886-7.
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    • Wang, L., Y. Kuroiwa, T. Kamitani, T. Takahashi, Y. Suzuki, and O. Hasegawa. “Effect of interstimulus interval on visual P300 in Parkinson's disease.” J Neurol Neurosurg Psychiatry 67, no. 4 (October 1999): 497–503. https://doi.org/10.1136/jnnp.67.4.497.
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    • Wang, L., Y. Kuroiwa, and T. Kamitani. “Visual event-related potential changes at two different tasks in nondemented Parkinson's disease.” J Neurol Sci 164, no. 2 (April 1, 1999): 139–47. https://doi.org/10.1016/s0022-510x(99)00060-x.
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  • Book Sections

    • Wang, L., and J. R. Petrella. “Neurodegenerative disorders.” In Functional Neuroimaging: A Clinical Approach, 129–60, 2019.

  • Conference Papers

    • Zhang, Lintao, Minhui Yu, Lihong Wang, David C. Steffens, Rong Wu, Guy G. Potter, and Mingxia Liu. “Understanding Clinical Progression of Late-Life Depression to Alzheimer's Disease Over 5 Years with Structural MRI.” In Mach Learn Med Imaging, 13583:259–68, 2022. https://doi.org/10.1007/978-3-031-21014-3_27.
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    • Yang, E., L. Wang, D. Steffens, G. Potter, and M. Liu. “Deep factor regression for computer-aided analysis of major depressive disorders with structural MRI data.” In Proceedings  International Symposium on Biomedical Imaging, 2021-April:208–11, 2021. https://doi.org/10.1109/ISBI48211.2021.9433817.
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