Linfeng Huang
Associate Professor of Biology at Duke Kunshan University

Prof. Linfeng Huang received his Bachelor of Science degree from the College of Biological Sciences, China Agricultural University in Beijing in 2003. After graduation, he did a short academic visit at the Centre for Ecology and Hydrology - Oxford and then studied his PhD with Prof. Sir David Baulcombe at the Sainsbury Laboratory, the John Innes Centre in the UK. He obtained his PhD degree from the University of East Anglia in 2009. Between 2009 and 2014, he did his postdoctoral training with Prof. Judy Lieberman at Boston Children’s Hospital and Harvard Medical School in the USA. Since Aug 2014, he was an Assistant Professor and then an Associate Professor (tenured) at the Department of Biomedical Sciences, City University of Hong Kong. Prof. Huang joined Duke Kunshan University as an Associate Professor of Biology in Sep 2020.

Current Research Interests

Prof. Huang is passionate about pursuing fundamental questions in RNA biology and firmly believes such knowledge can be exploited to create powerful RNA-based biotechnology and therapeutics. His research is mainly in the RNA interference (RNAi) field. Recently he discovered a species of bacterial small RNAs which is similar to eukaryotic small interfering RNA (siRNA). Those bacterial small RNAs, named pro-siRNAs (for prokaryotic siRNAs), were stabilized by ectopic expression of p19, a plant viral siRNA binding protein. Based on this discovery, he invented a technology of producing gene specific and highly efficient ‘recombinant’ siRNAs in bacteria.
Currently, Prof. Huang’s research focuses on developing pro-siRNA-based RNAi technology and using high-throughput RNAi screen to study human diseases.

Current Appointments & Affiliations

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