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Linfeng Huang

Associate Professor of Biology at Duke Kunshan University
DKU Faculty

Overview


Prof. Linfeng Huang received his Bachelor of Science degree from the College of Biological Sciences, China Agricultural University in Beijing in 2003. After graduation, he did a short academic visit at the Centre for Ecology and Hydrology - Oxford and then studied his PhD with Prof. Sir David Baulcombe at the Sainsbury Laboratory, the John Innes Centre in the UK. He obtained his PhD degree from the University of East Anglia in 2009. Between 2009 and 2014, he did his postdoctoral training with Prof. Judy Lieberman at Boston Children’s Hospital and Harvard Medical School in the USA. Since Aug 2014, he was an Assistant Professor and then an Associate Professor (tenured) at the Department of Biomedical Sciences, City University of Hong Kong. Prof. Huang joined Duke Kunshan University as an Associate Professor of Biology in Sep 2020.

Current Appointments & Affiliations


Associate Professor of Biology at Duke Kunshan University · 2020 - Present DKU Faculty

Recent Publications


Single-cell encoded gene silencing for high-throughput combinatorial siRNA screening.

Journal Article Nature communications · November 2024 The use of combinatorial siRNAs shows great promise for drug discovery, but the identification of safe and effective siRNA combinations remains challenging. Here, we develop a massively multiplexed technology for systematic screening of siRNA-based cocktai ... Full text Cite

H3K27me3-mediated epigenetic regulation in pluripotency maintenance and lineage differentiation.

Journal Article Cell insight · August 2024 Cell fate determination is an intricate process which is orchestrated by multiple regulatory layers including signal pathways, transcriptional factors, epigenetic modifications, and metabolic rewiring. Among the sophisticated epigenetic modulations, the re ... Full text Cite

Liver cancer cells as the model for developing liver-targeted RNAi therapeutics.

Journal Article Biochemical and biophysical research communications · February 2023 RNAi is a sequence-specific gene regulation mechanism that involves small interfering RNAs (siRNAs). RNAi therapeutic has become a new class of precision medicine and has shown great potential in treating liver-associated diseases, especially metabolic dis ... Full text Cite
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Education, Training & Certifications


University of East Anglia (United Kingdom) · 2009 Ph.D.

External Links


Huang lab website