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Linfeng Huang

Associate Professor of Biology at Duke Kunshan University
DKU Faculty

Research Interests

Prof. Huang is passionate about pursuing fundamental questions in RNA biology and firmly believes such knowledge can be exploited to create powerful RNA-based biotechnology and therapeutics. His research is mainly in the RNA interference (RNAi) field. Recently he discovered a species of bacterial small RNAs which is similar to eukaryotic small interfering RNA (siRNA). Those bacterial small RNAs, named pro-siRNAs (for prokaryotic siRNAs), were stabilized by ectopic expression of p19, a plant viral siRNA binding protein. Based on this discovery, he invented a technology of producing gene specific and highly efficient ‘recombinant’ siRNAs in bacteria.
Currently, Prof. Huang’s research focuses on developing pro-siRNA-based RNAi technology and using high-throughput RNAi screen to study human diseases.