Scholars@Duke
Lisa Mei-ling Ho

Lisa Mei-ling Ho

Associate Professor of Radiology
Radiology, Abdominal Imaging
lisa.ho@duke.edu
Box 3808 Med Ctr, Durham, NC 27710
Dept of Radiology, Durham, NC 27710

Selected Publications

Splenic imaging and non-vascular intervention: when to intervene on the spleen and how to do it safely.

Journal Article Abdominal radiology (New York) · April 2025 Cross-sectional interventional radiology (CSIR) for the spleen has evolved over the past two decades. Contemporary data show that CT- and US-guided splenic procedures are safer than once assumed, allowing for biopsy and drainage when clinically appropriate ... Full text Cite

Increasing utilization of contrast-enhanced ultrasound during abdominal biopsies: impact of an educational training program.

Journal Article J Ultrasound · June 2024 RATIONAL AND OBJECTIVES: To increase utilization of contrast-enhanced ultrasound (CEUS) during ultrasound-guided targeted liver biopsies. MATERIAL AND METHODS: Two educational training interventions performed to increase use of CEUS. First, 14 radiologists ... Full text Link to item Cite

Simplifying risk stratification for thyroid nodules on ultrasound: validation and performance of an artificial intelligence thyroid imaging reporting and data system.

Journal Article Curr Probl Diagn Radiol · 2024 PURPOSE: To validate the performance of a recently created risk stratification system (RSS) for thyroid nodules on ultrasound, the Artificial Intelligence Thyroid Imaging Reporting and Data System (AI TI-RADS). MATERIALS AND METHODS: 378 thyroid nodules fr ... Full text Link to item Cite

Deep learning for classification of thyroid nodules on ultrasound: validation on an independent dataset.

Journal Article Clin Imaging · July 2023 OBJECTIVES: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. METHODS: Prior study presented an algorithm which is able to detect thyroid ... Full text Link to item Cite

Needle types used in abdominal cross-sectional interventional radiology: a survey of the Society of Abdominal Radiology emerging technology commission.

Journal Article Abdom Radiol (NY) · August 2022 PURPOSE: To identify commonly used needle types in cross-sectional interventional radiology (CSIR) and to review features and safety profiles of those needles. METHODS: Members of the Society of Abdominal Radiology (SAR) emerging technologies commission (E ... Full text Link to item Cite

Comparison of clinical efficacy, subjective user experience, and safety for two different core biopsy needles, the Achieve® and Marquee®.

Journal Article Abdom Radiol (NY) · August 2022 PURPOSE: To compare clinical efficacy, subjective radiologist preference, and complication rates for two different core biopsy needles, the Achieve® and Marquee®. METHODS: Retrospective review included consecutive patients who underwent 18 gauge non-target ... Full text Link to item Cite

Automated Structured Reporting for Thyroid Ultrasound: Effect on Reporting Errors and Efficiency.

Journal Article J Am Coll Radiol · February 2021 PURPOSE: To compare the effectiveness of different reporting templates using the ACR Thyroid Imaging Reporting and Data System (TI-RADS) for thyroid ultrasound. METHODS: In this retrospective study, four radiologists implemented ACR TI-RADS while dictating ... Full text Open Access Link to item Cite

Ultrasound-guided non-targeted liver core biopsy: comparison of the efficacy of two different core needle biopsy systems using an ex-vivo animal model and retrospective review of clinical experience.

Journal Article Clin Imaging · May 2020 PURPOSE: To compare the efficacy of two 18-gauge core needle biopsy systems, the Achieve® (Merit Medical) and the Marquee® (BD Bard), using an ex-vivo animal liver model and retrospective review of clinical experience. METHODS: Sixty ex-vivo liver biopsy s ... Full text Link to item Cite

Can Texture Analysis Be Used to Distinguish Benign From Malignant Adrenal Nodules on Unenhanced CT, Contrast-Enhanced CT, or In-Phase and Opposed-Phase MRI?

Journal Article AJR Am J Roentgenol · March 2019 OBJECTIVE: The purpose of this study is to determine whether second-order texture analysis can be used to distinguish lipid-poor adenomas from malignant adrenal nodules on unenhanced CT, contrast-enhanced CT (CECT), and chemical-shift MRI. MATERIALS AND ME ... Full text Link to item Cite

Comparison of Visualization Rates of LI-RADS Version 2014 Major Features With IV Gadobenate Dimeglumine or Gadoxetate Disodium in Patients at Risk for Hepatocellular Carcinoma.

Journal Article AJR Am J Roentgenol · June 2018 OBJECTIVE: The purpose of this study is to compare visualization rates of the major features covered by Liver Imaging Reporting and Data System (LI-RADS) version 2014 in patients at risk for hepatocellular carcinoma using either gadobenate dimeglumine or g ... Full text Link to item Cite

Clinically Acceptable Optimized Dose Reduction in Computed Tomographic Imaging of Necrotizing Pancreatitis Using a Noise Addition Software Tool.

Journal Article J Comput Assist Tomogr · 2018 OBJECTIVE: This study aimed to determine potential radiation dose reduction of contrast-enhanced computed tomography (CECT) for imaging necrotizing pancreatitis (NP) using a noise addition tool. METHODS: Eighty-four patients were identified with at least 1 ... Full text Link to item Cite

Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality.

Journal Article Abdom Imaging · October 2015 PURPOSE: To prospectively evaluate whether clinical experience with an adaptive statistical iterative reconstruction algorithm (ASiR) has an effect on radiologists' diagnostic performance and confidence for the diagnosis of hypervascular liver tumors, as w ... Full text Link to item Cite

Diagnostic performance of imaging criteria for distinguishing autoimmune cholangiopathy from primary sclerosing cholangitis and bile duct malignancy.

Journal Article Abdom Imaging · October 2015 OBJECTIVE: To determine the diagnostic performance of imaging criteria for distinguishing Ig-G4-associated autoimmune cholangiopathy (IAC) from primary sclerosing cholangitis (PSC) and bile duct malignancy. METHODS: A medical records search between January ... Full text Link to item Cite

Management of Anticoagulant and Antiplatelet Medications in Adults Undergoing Percutaneous Interventions.

Journal Article AJR Am J Roentgenol · August 2015 OBJECTIVE: Many radiologists are unfamiliar with the new antithrombogenic medications and how to modify patient management before nonvascular percutaneous procedures performed in a radiology department. In this article, we review the indications for use, m ... Full text Link to item Cite

Dual-energy multidetector CT for the characterization of incidental adrenal nodules: diagnostic performance of contrast-enhanced material density analysis.

Journal Article Radiology · February 2015 PURPOSE: To determine whether contrast material-enhanced dual-energy multidetector computed tomography (CT) with material decomposition analysis allows differentiation of adrenal adenomas from nonadenomatous lesions and to compare findings with those of no ... Full text Link to item Cite

Adrenal glands

Chapter · May 1, 2014 The adrenal glands can develop a myriad of abnormalities, which can be fundamentally differentiated into benign or malignant lesions having either hyperfunction or non-hyperfunction (i.e., non-function) [1, 2]. Functioning lesions typically secrete hormona ... Full text Cite

Fulminant herpes simplex viral hepatitis: ultrasound and CT imaging appearance and a review of the imaging literature.

Journal Article Clin Imaging · 2014 We report the case of a previously healthy 21-year-old woman who presented 6 days post-partum in acute fulminant hepatic failure. A liver ultrasound demonstrated normal echogenicity without discrete nodules while an enhanced computed tomography (CT) demons ... Full text Link to item Cite

Adrenal Glands

Chapter · 2014 Full text Cite

Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique.

Journal Article Eur Radiol · December 2013 OBJECTIVES: To investigate the impact of an adaptive statistical iterative reconstruction (ASiR) algorithm on diagnostic accuracy and confidence for the diagnosis of hypervascular liver tumours, as well as the reader's perception of image quality, using a ... Full text Link to item Cite

FDG-PET/CT characterization of adrenal nodules: diagnostic accuracy and interreader agreement using quantitative and qualitative methods.

Journal Article Acad Radiol · August 2013 PURPOSE: To determine interreader agreement and diagnostic accuracy across varying levels of reader experience using qualitative and quantitative methods of evaluating adrenal nodules using ((18)F)-fluorodeoxyglucose-positron emission tomography/computed t ... Full text Link to item Cite

The incarcerated uterus: a review of MRI and ultrasound imaging appearances.

Journal Article AJR Am J Roentgenol · July 2013 OBJECTIVE: The objective of this article is to review the MRI and ultrasound appearances of incarcerated uterus. CONCLUSION: Incarcerated uterus is a rare but serious complication of pregnancy in which the gravid uterus becomes trapped in the posterior pel ... Full text Link to item Cite

Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?

Journal Article J Magn Reson Imaging · February 2013 PURPOSE: To evaluate the value of hepatobiliary phase imaging for detection and characterization of hepatocellular carcinoma (HCC) in liver MRI with Gd-EOB-DTPA, in a North American population. MATERIALS AND METHODS: One hundred MRI examinations performed ... Full text Link to item Cite

Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?

Journal Article J Comput Assist Tomogr · 2013 OBJECTIVE: The objectives of this study were to explore utilization of multi-detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction. METHODS: An electronic mai ... Full text Link to item Cite

Dual-energy CT applications in the abdomen.

Journal Article AJR Am J Roentgenol · November 2012 OBJECTIVE: The purpose of this article is to give a brief overview of the technical background of dual-energy CT (DECT) imaging and to review various DECT applications in the abdomen that are currently available for clinical practice. In a review of the re ... Full text Link to item Cite

Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?

Journal Article AJR Am J Roentgenol · April 2012 OBJECTIVE: The purpose of our study was to investigate whether virtual unenhanced adrenal nodule attenuation values can replace true noncontrast attenuation values. MATERIALS AND METHODS: Twenty-three incidentally discovered adrenal nodules (19 adenomas an ... Full text Link to item Cite

Histogram analysis of small solid renal masses: differentiating minimal fat angiomyolipoma from renal cell carcinoma.

Journal Article AJR Am J Roentgenol · February 2012 OBJECTIVE: The objective of our study was to retrospectively determine whether minimal fat renal angiomyolipoma can be differentiated from clear cell or papillary renal cell carcinoma (RCC) in small renal masses using attenuation measurement histogram anal ... Full text Link to item Cite

Imaging appearance of surgical sponges at 1.5 T MRI: an in vitro study.

Journal Article Eur J Radiol · November 2011 OBJECTIVE: To predict the MR appearance of retained surgical textiles in the acute setting by using an in vitro phantom and body MR imaging protocols. METHODS: Three surgical sponges were embedded in clear gelatin. One of these sponges was soaked in fresh ... Full text Link to item Cite

Pneumatosis intestinalis and pneumoperitoneum after bilateral lung transplantation in adults.

Journal Article AJR Am J Roentgenol · March 2011 OBJECTIVE: The purpose of this article is to determine the clinical features, imaging findings, and possible causes of pneumatosis intestinalis (PI) or pneumoperitoneum that developed in bilateral lung transplant recipients. MATERIALS AND METHODS: From Dec ... Full text Link to item Cite

Detection of pancreatic tumors, image quality, and radiation dose during the pancreatic parenchymal phase: effect of a low-tube-voltage, high-tube-current CT technique--preliminary results.

Journal Article Radiology · August 2010 PURPOSE: To intraindividually compare a low-tube-voltage (80 kVp), high-tube-current (675 mA) computed tomographic (CT) technique with a high-tube-voltage (140 kVp) CT protocol for the detection of pancreatic tumors, image quality, and radiation dose durin ... Full text Link to item Cite

Dual-energy CT for characterization of adrenal nodules: initial experience.

Journal Article AJR Am J Roentgenol · June 2010 OBJECTIVE: The purpose of this study was to determine whether use of dual-energy technique can improve the diagnostic performance of CT in the differential diagnosis of adrenal adenomas and metastatic lesions. SUBJECTS AND METHODS: Thirty-one adrenal nodul ... Full text Link to item Cite

Percutaneous abscess drainage in patients with perforated acute appendicitis: effectiveness, safety, and prediction of outcome.

Journal Article AJR Am J Roentgenol · February 2010 OBJECTIVE: The purposes of this study were to retrospectively investigate the effectiveness and safety of CT-guided percutaneous drainage in the treatment of patients with acute appendicitis complicated by perforation and to identify CT findings and proced ... Full text Link to item Cite

Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?

Journal Article Radiographics · 2010 Dual-energy CT provides information about how substances behave at different energies, the ability to generate virtual unenhanced datasets, and improved detection of iodine-containing substances on low-energy images. Knowing how a substance behaves at two ... Full text Link to item Cite

Dual energy versus single energy MDCT: measurement of radiation dose using adult abdominal imaging protocols.

Journal Article Acad Radiol · November 2009 Featured Publication RATIONALE AND OBJECTIVES: The aim of this study was to measure the radiation dose of dual-energy and single-energy multidetector computed tomographic (CT) imaging using adult liver, renal, and aortic imaging protocols. MATERIALS AND METHODS: Dual-energy CT ... Full text Link to item Cite

Hypervascular liver tumors: low tube voltage, high tube current multidetector CT during late hepatic arterial phase for detection--initial clinical experience.

Journal Article Radiology · June 2009 Featured Publication PURPOSE: To intraindividually compare a low tube voltage (80 kVp), high tube current computed tomographic (CT) technique with a standard CT protocol (140 kVp) in terms of image quality, radiation dose, and detection of malignant hypervascular liver tumors ... Full text Link to item Cite

Adrenal nodules at FDG PET/CT in patients known to have or suspected of having lung cancer: a proposal for an efficient diagnostic algorithm.

Journal Article Radiology · February 2009 Featured Publication PURPOSE: To develop an algorithm to maximize the diagnostic yield of positron emission tomography (PET)/computed tomography (CT) by using defined attenuation and standardized uptake value (SUV) criteria. MATERIALS AND METHODS: An IRB-approved, HIPAA-compli ... Full text Link to item Cite

Lipid-poor adenomas on unenhanced CT: does histogram analysis increase sensitivity compared with a mean attenuation threshold?

Journal Article AJR Am J Roentgenol · July 2008 Featured Publication OBJECTIVE: The purpose of our study was to evaluate the efficacy of CT histogram analysis for further characterization of lipid-poor adenomas on unenhanced CT. MATERIALS AND METHODS: One hundred thirty-two adrenal nodules were identified in 104 patients wi ... Full text Link to item Cite

Conventional and reduced radiation dose of 16-MDCT for detection of nephrolithiasis and ureterolithiasis.

Journal Article AJR Am J Roentgenol · January 2008 Featured Publication OBJECTIVE: Our purpose was to prospectively compare the reader compatibility and acceptability of a range of reduced-dose 16-MDCT images with standard-dose 16-MDCT images for the detection of nephroureterolithiasis using a dose reduction simulation techniq ... Full text Link to item Cite

New classes of anticoagulation and antiplatelet agents: preprocedure management and safety guidelines for imaging-guided intervention.

Journal Article J Comput Assist Tomogr · 2008 Featured Publication OBJECTIVE: New medications are available for prophylaxis of deep venous thrombosis, the treatment of venous thromboembolism, and also to reduce the risk of acute coronary syndrome and stroke. The purpose of this review is to provide the radiologist a pract ... Full text Link to item Cite

Pneumatosis intestinalis in the adult: benign to life-threatening causes.

Journal Article AJR Am J Roentgenol · June 2007 Featured Publication OBJECTIVE: The frequency of detection of pneumatosis intestinalis (PI) appears to be increasing. This increase may be the result of increased CT use. New medications and surgical procedures have been reported to be associated with an increase in the incide ... Full text Link to item Cite

Magnetic resonance (MR) cholangiography: quantitative and qualitative comparison of 3.0 Tesla with 1.5 Tesla.

Journal Article Invest Radiol · June 2007 Featured Publication OBJECTIVES: To determine quantitative and qualitative image quality in patients undergoing magnetic resonance (MR) cholangiography at 3.0 Tesla (T) compared with 1.5 T. MATERIALS AND METHODS: Fifty patients (30 women; mean age, 51 years) underwent MR chola ... Full text Link to item Cite

Determining contrast medium dose and rate on basis of lean body weight: does this strategy improve patient-to-patient uniformity of hepatic enhancement during multi-detector row CT?

Journal Article Radiology · May 2007 Featured Publication PURPOSE: To prospectively evaluate the use of lean body weight (LBW) as the main determinant of the volume and rate of contrast material administration during multi-detector row computed tomography of the liver. MATERIALS AND METHODS: This HIPAA-compliant ... Full text Link to item Cite

Contrast-enhanced hepatic magnetic resonance angiography at 3 T: does parallel imaging improve image quality?

Journal Article J Comput Assist Tomogr · 2007 Featured Publication PURPOSE: To evaluate whether hepatic magnetic resonance angiography (MRA) performed at 3 T and acquired with a parallel imaging acceleration factor of 2 provides satisfactory image quality and adequate contrast-to-noise, compared with an acquisition withou ... Full text Link to item Cite

Pneumatosis intestinalis after lung transplant.

Journal Article Abdom Imaging · 2005 Featured Publication Pneumatosis intestinalis may be idiopathic or associated with numerous conditions. Uncommonly, it has been associated with organ transplantation. We report one case of pneumatosis intestinalis after lung transplantation in an adult patient. To our knowledg ... Full text Link to item Cite

Artificial urethral sphincter

Conference AMERICAN JOURNAL OF ROENTGENOLOGY · January 1, 2005 Link to item Cite

Abdominal aortic aneurysms at multi-detector row helical CT: optimization with interactive determination of scanning delay and contrast medium dose.

Journal Article Radiology · September 2004 Featured Publication PURPOSE: To prospectively evaluate a technique for optimizing aortoiliac enhancement at multi-detector row helical computed tomography (CT) with both the scanning delay and contrast medium dose determined by using an interactive method. MATERIALS AND METHO ... Full text Link to item Cite

Percutaneous biopsy of periarterial soft tissue cuffs in the diagnosis of pancreatic carcinoma.

Journal Article Abdom Imaging · 2004 Pancreatic cancer may present on computed tomography (CT) as an isolated cuff of tumor surrounding the superior mesenteric artery (SMA) or celiac trunk, without an identifiable pancreatic mass. We reviewed our experience with imaging-guided biopsy of the s ... Full text Link to item Cite

Usefulness of sonographic guidance during percutaneous biopsy of mesenteric masses.

Journal Article AJR Am J Roentgenol · June 2003 Featured Publication OBJECTIVE: The objective of our study was to determine the usefulness of sonographic guidance for biopsy of mesenteric masses. MATERIALS AND METHODS: Twenty-five sonographically guided percutaneous biopsies of mesenteric masses were performed in 23 patient ... Full text Link to item Cite

Simple pancreatic cysts: CT and endosonographic appearances.

Journal Article AJR Am J Roentgenol · April 2002 OBJECTIVE. This report describes the CT and endoscopic sonographic appearance of simple pancreatic cysts in three adults. CONCLUSION. Simple pancreatic cysts are typically an incidental finding in adults who have no history of pancreatic disease. The imagi ... Full text Link to item Cite

Isolated primary non-hodgkin's lymphoma of the esophagus.

Journal Article AJR Am J Roentgenol · February 2001 Full text Link to item Cite

Vaginal opacification during defecography: utility of placing a folded gauze square at the introitus.

Journal Article Abdom Imaging · 1999 We evaluated the value of placement of a folded gauze square into the urogenital introitus to improve vaginal opacification in 90 patients who underwent defecography. Of the 50 patients who retained the gauze in the introitus, 96% demonstrated excellent or ... Full text Link to item Cite

Vaginal opacification during defecography: direction of vaginal migration aids in diagnosis of pelvic floor pathology.

Journal Article Abdom Imaging · 1999 BACKGROUND: To determine whether direction of vaginal displacement during defecography aids in diagnosing pelvic floor pathology. METHODS: Ninety patients underwent defecography over a 2-year period. Each study was retrospectively reviewed by three radiolo ... Full text Link to item Cite