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Liuyang Wang

Assistant Research Professor of Molecular Genetics and Microbiology
Molecular Genetics and Microbiology
0049 CARL, Box 3053, Durham, NC 27710
0049 CARL Box 3053 DUMC, 213 Research Drive, Durham, NC 27710

Overview


Leveraging bioinformatics and big data to understand the intricacies of human diseases.

My overall research goals are centered on unraveling the molecular mechanism underpinning human disease susceptibility and harnessing these findings to innovative diagnostic and therapeutic strategies. I have adopted a multidisciplinary approach that integrates genomics, transcriptomics, and computational biology. Leveraging high-throughput cellular screening and genome-wide association study (GWAS), we have successfully identified hundreds of genomic loci associated with 8 different pathogens (Wang et al. 2018). Utilizing single-cell RNA-seq, we developed scHi-HOST to rapidly identify host genes associated with the influenza virus (Schott and Wang, et al. 2022). I also have developed several novel statistical tools, CPAG and iCPAGdb, that estimate genetic associations among human diseases and traits (Wang et al. 2015, 2021). Combining experimental and computational approaches, I expect to gain a deeper understanding of the genetic architecture of human susceptibility to infection and inflammatory disorders.

Current Appointments & Affiliations


Assistant Research Professor of Molecular Genetics and Microbiology · 2019 - Present Molecular Genetics and Microbiology, Basic Science Departments

Education, Training & Certifications


Chinese Academy of Medical Sciences (China) · 2009 Ph.D.