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Lori Ann Orlando

Professor of Medicine
Medicine, General Internal Medicine
102906, Aesthetic Center 2nd Floor, Durham, NC 27705
3475 Erwin Rd, 2nd Floor Aesthetics Bldg, Durham, NC 27705

Research Interests


Family health history and genomics, improving risk assessment for healthy patients and integration with clinical workflow, development and integration of multiple data streams and data types into clinical decision support platforms using data standards such as SMART-FHIR.

Selected Grants


Deploying a genomic-medicine risk assessment model for diverse primary care populations and settings

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2026

Building and Deploying a Genomic-Medicine Risk Assessment Model for Diverse Primary Care Populations.

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2025

The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network-Coordinating Center

ResearchPrincipal Investigator · Awarded by Vanderbilt University Medical Center · 2020 - 2025

Implementing Pharmacogenomics in Diverse Health Care Systems

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2024

Postdoctoral Training in Genomic Medicine Research

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2017 - 2023

VGER, The Vanderbilt Genome-Electronic Records Project

ResearchPrincipal Investigator · Awarded by Vanderbilt University Medical Center · 2018 - 2020

Implementation, Adoption, and Utility of Family History in Diverse Care Settings

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2013 - 2019

VA Metree Subaward

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2016 - 2019

Genome Medical Pilot

ResearchPrincipal Investigator · Awarded by Genome Medical, Inc · 2017 - 2017

Comparative Effectiveness Reveiws for MMA Section 1013

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2005 - 2008

External Relationships


  • MeTree&You

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.