Neil Ross MacIntyre Jr. | Scholars@Duke

Neil Ross MacIntyre Jr.
Professor of Medicine

1) Mechanical Ventilation and respiratory failure. Current projects involve studying patient-ventilator interactions during modes of support that require patient activity. The focus is on ventilatory muscle function during these assisted modes. Other projects include evaluating respiratory system mechanics in acute respiratory failure and the role of ECMO in the adult. Duke is also one of several institutions in the NIH ARDS Network, a consortium designed to perform multi-center trials.

2) Diffusing capacity of the lung for carbon monoxide. Current projects involve using a rapidly responding gas analyzer to measure lung diffusing capacity in discrete regions of the lung. These analyses are being extended into mechanically ventilated patients.

3) COPD. Current projects involve studying the physiology of cardio-respiratory conditioning in patients with obstructive lung disease and the role of pulmonary rehabilitation in improving COPD outcomes. Duke is also a member of two NIH sponsored multicenter programs: the COPDgene project correlating genetic profiles with physiologic/clinical phenotypes; and the NIH LOTT project evaluating the role of oxygen therapy in exercise and sleep hypoxemia.

4) Aerosol delivery systems. The current project is the development of a prototype aerosol generating catheter that can be directly inserted into the airways. Studies are being conducted in both ex vivo animal lungs and in mechanically ventilated patients.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 1995

Contact Information

1120 Hosp North, Durham, NC 27710
Duke Box 3911, Durham, NC 27710
macin001@mc.duke.edu (919) 681-2720

Background
Education, Training, & Certifications
- M.D., Cornell University 1972
Duke Appointment History
- Vice-Chair for Clinical Affairs - Hospital, Medicine, Clinical Science Departments 2005 - 2007
- Interim Chief, Division of Pulmonary, Allergy and Critical Care Medical, Medicine, Clinical Science Departments 2004 - 2006
- Acting Chief, Division of Pulm and Critical Care Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 1999 - 2000
- Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 1989 - 1995
Research
Selected Grants
- Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2020
- Vyaire Educational Workshop awarded by Vyaire Medical, Inc. 2017 - 2020
- Respiratory Compromise & Unplanned Intubations awarded by Respiratory Compromise Institute 2018
- Clinical Calibration of a Digital, Low Cost Spirometry Device awarded by Vigor Medical Systems 2018
- Effects of Teleflex Catheter on Ventilator Mechanics awarded by Teleflex, Inc. 2018
- Human Lung Regional Ventilation Defect Severity Measured by Fluorine-19 Gas MRI awarded by National Institutes of Health 2012 - 2018
- Mallinckrodt Educational Workshop awarded by Mallinckrodt Pharmaceuticals 2017
- GSK Study CTT116855 awarded by GlaxoSmithKline 2015 - 2017
- LOTT Option IV Core awarded by National Institutes of Health 2006 - 2016
- LOTT Option 1 awarded by National Institutes of Health 2006 - 2016
- LOTT Option II awarded by National Institutes of Health 2006 - 2016
- LOTT Option III awarded by National Institutes of Health 2006 - 2016
- ARDSNet Option 5 extension awarded by National Institutes of Health 2005 - 2014
- Idiopathic Pulmonary Fibrosis Clinical Research Network awarded by National Institutes of Health 2005 - 2014
- Telephone-based coping skills training for COPD awarded by National Institutes of Health 2000 - 2014
- SAILS awarded by National Institutes of Health 2010 - 2014
- ARDSNet Option 4 awarded by National Institutes of Health 2011 - 2013
- Long-term Oxygen Treatment Trial (LOTT) - Regional Clinical Centers (RCCs) awarded by National Institutes of Health 2006 - 2012
- Clinical Centers for a Clinical Research Network for the Treatment of ALI and ARDS awarded by National Institutes of Health 2005 - 2011
- Measuring/Improving Quality of Life in Acute Lung Injury awarded by National Institutes of Health 2005 - 2010
- Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 1982 - 2009
- Weaning Preterm Infants from Mechanical Ventilation awarded by National Institutes of Health 2003 - 2006
- Clinical Centers For A Clinical Network For The Treatment awarded by National Institutes of Health 1994 - 2006
- Clinical Centers For Lung Volume Reduction Surgery For Emp awarded by National Institutes of Health 1996 - 2005
Publications & Artistic Works
Selected Publications
- Book Sections
  - Radcliff, V, and MacIntyre, N. "Mechanical ventilation." In Surgical Intensive Care Medicine, Third Edition, 335-347. January 1, 2016. Full Text
- Conference Papers
  - Schoenberg, NC, Barker, AF, Bernardo, J, Deterding, RR, Ellner, JJ, Hess, DR, MacIntyre, NR, Martinez, FJ, and Wilson, KC. "A Comparative Analysis of Pulmonary and Critical Care Medicine Guideline Development Methodologies." September 2017. Full Text
- Journal Articles
  - MacIntyre, NR, Gentile, M, Davies, J, Bergin, S, Rackley, C, and Mathews, A. "Airway pressure release ventilation: a step forward?." Intensive care medicine 44, no. 2 (February 2018): 272-. (Letter) Full Text
  - Paul, DW, Lagat, DK, MacIntyre, N, Egger, JR, Murdoch, DM, Que, LG, and Kussin, PS. "Validation of spirometry prediction equations in western Kenya." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 22, no. 1 (January 2018): 112-118. Full Text
  - Yusen, RD, Criner, GJ, Sternberg, AL, Au, DH, Fuhlbrigge, AL, Albert, RK, Casaburi, R, Stoller, JK, Harrington, KF, Cooper, JAD, Diaz, P, Gay, S, Kanner, R, MacIntyre, N, Martinez, FJ, Piantadosi, S, Sciurba, F, Shade, D, Stibolt, T, Tonascia, J, Wise, R, Bailey, WC, Bailey, WC, Fuhlbrigge, AL, Sampong, E, Sloan, K, Wagner, A, Anderson, S, Moy, M, Okunbor, O, Stoller, JK, Marlow, S, Meli, Y, Rice, R, Aboussouan, LS, Castele, R, Parambil, J, Khatri, S, Pande, A, Zein, J, Olbrych, T, and Alkins, S et al. "The Long-Term Oxygen Treatment Trial for Chronic Obstructive Pulmonary Disease: Rationale, Design, and Lessons Learned." Annals of the American Thoracic Society 15, no. 1 (January 2018): 89-101. Full Text
  - Culver, BH, Graham, BL, Coates, AL, Wanger, J, Berry, CE, Clarke, PK, Hallstrand, TS, Hankinson, JL, Kaminsky, DA, MacIntyre, NR, McCormack, MC, Rosenfeld, M, Stanojevic, S, Weiner, DJ, and ATS Committee on Proficiency Standards for Pulmonary Function Laboratories, . "Recommendations for a Standardized Pulmonary Function Report. An Official American Thoracic Society Technical Statement." American journal of respiratory and critical care medicine 196, no. 11 (December 2017): 1463-1472. Full Text
  - MacIntyre, NR. "Humidified High-Flow Nasal Cannula Oxygen-More Than Just Supplemental Oxygen." Critical care medicine 45, no. 12 (December 2017): 2103-2104. Full Text
  - Giovacchini, CX, Mathews, AM, Lawlor, BR, and MacIntyre, NR. "Titrating Oxygen Requirements During Exercise: Evaluation of a Standardized Single Walk Test Protocol." Chest (November 20, 2017). Full Text
  - Boueiz, A, Chang, Y, Cho, MH, Washko, GR, San José Estépar, R, Bowler, RP, Crapo, JD, DeMeo, DL, Dy, JG, Silverman, EK, Castaldi, PJ, Crapo, J, Silverman, E, Make, B, Regan, E, Beaty, T, Laird, N, Lange, C, Cho, MH, Santorico, S, Hokanson, J, DeMeo, D, Hansel, N, Hersh, C, Castaldi, P, McDonald, M-L, Wan, E, Hardin, M, Hetmanski, J, Parker, M, Foreman, M, Hobbs, B, Busch, R, Boueiz, A, Castaldi, P, Hardin, M, Qiao, D, Regan, E, Halper-Stromberg, E, Begum, F, Won, S, Lutz, S, and Lynch, DA et al. "Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression." Chest (September 2017). Full Text
  - Morris, TA, Gay, PC, MacIntyre, NR, Hess, DR, Hanneman, SK, Lamberti, JP, Doherty, DE, Chang, L, and Seckel, MA. "Respiratory Compromise as a New Paradigm for the Care of Vulnerable Hospitalized Patients." Respiratory care 62, no. 4 (April 2017): 497-512. Full Text
  - Miller, AG, and MacIntyre, NR. "Initial Ventilator Settings in the Emergency Department." Annals of emergency medicine 69, no. 2 (February 2017): 266-267. (Letter) Full Text
  - Graham, BL, Brusasco, V, Burgos, F, Cooper, BG, Jensen, R, Kendrick, A, MacIntyre, NR, Thompson, BR, and Wanger, J. "2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung." The European respiratory journal 49, no. 1 (January 3, 2017). Full Text
  - Graham, BL, Brusasco, V, Burgos, F, Cooper, BG, Jensen, R, Kendrick, A, MacIntyre, NR, Thompson, BR, and Wanger, J. "Executive Summary: 2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung." The European respiratory journal 49, no. 1 (January 3, 2017). Full Text
  - MacIntyre, N. "Design Features of Modern Mechanical Ventilators." Clinics in chest medicine 37, no. 4 (December 2016): 607-613. (Review) Full Text
  - MacIntyre, N. "Evolving Concepts in Mechanical Ventilation." Clinics in chest medicine 37, no. 4 (December 2016): xiii-. Full Text
  - Long-Term Oxygen Treatment Trial Research Group, , Albert, RK, Au, DH, Blackford, AL, Casaburi, R, Cooper, JA, Criner, GJ, Diaz, P, Fuhlbrigge, AL, Gay, SE, Kanner, RE, MacIntyre, N, Martinez, FJ, Panos, RJ, Piantadosi, S, Sciurba, F, Shade, D, Stibolt, T, Stoller, JK, Wise, R, Yusen, RD, Tonascia, J, Sternberg, AL, and Bailey, W. "A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation." The New England journal of medicine 375, no. 17 (October 2016): 1617-1627. Full Text
  - Sun, W, Kechris, K, Jacobson, S, Drummond, MB, Hawkins, GA, Yang, J, Chen, T-H, Quibrera, PM, Anderson, W, Barr, RG, Basta, PV, Bleecker, ER, Beaty, T, Casaburi, R, Castaldi, P, Cho, MH, Comellas, A, Crapo, JD, Criner, G, Demeo, D, Christenson, SA, Couper, DJ, Curtis, JL, Doerschuk, CM, Freeman, CM, Gouskova, NA, Han, MK, Hanania, NA, Hansel, NN, Hersh, CP, Hoffman, EA, Kaner, RJ, Kanner, RE, Kleerup, EC, Lutz, S, Martinez, FJ, Meyers, DA, Peters, SP, Regan, EA, Rennard, SI, and Scholand, MB et al. "Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD." PLoS genetics 12, no. 8 (August 17, 2016): e1006011-. Full Text
  - Macintyre, N. "Spontaneous breathing during mechanical ventilation: A two-edged sword." Critical Care Medicine 44, no. 8 (August 1, 2016): 1625-1626. Full Text
  - MacIntyre, N. "Measuring Clinical Performance: Make Sure the Ruler Is Accurate." Critical care medicine 44, no. 6 (June 2016): 1230-. Full Text
  - Nguyen, AP, Schmidt, UH, and MacIntyre, NR. "Should High-Frequency Ventilation in the Adult Be Abandoned?." Respiratory care 61, no. 6 (June 2016): 791-800. (Review) Full Text
  - Schmidt, UH, Knecht, L, and MacIntyre, NR. "Should Early Mobilization Be Routine in Mechanically Ventilated Patients?." Respiratory care 61, no. 6 (June 2016): 867-875. (Review) Full Text
  - Vaz Fragoso, CA, McAvay, G, Van Ness, PH, Casaburi, R, Jensen, RL, MacIntyre, N, Yaggi, HK, Gill, TM, and Concato, J. "Phenotype of Spirometric Impairment in an Aging Population." American journal of respiratory and critical care medicine 193, no. 7 (April 2016): 727-735. Full Text
  - MacIntyre, N. "Oxygen: Providing Too Much of a Good Thing?." Critical care medicine 44, no. 3 (March 2016): 641-. Full Text
  - MacIntyre, NR. "Lung Protective Ventilator Strategies: Beyond Scaling Tidal Volumes to Ideal Lung Size." Critical care medicine 44, no. 1 (January 2016): 244-245. Full Text
  - Andrade, JD, Schwarz, M, Collard, HR, Gentry-Bumpass, T, Colby, T, Lynch, D, Kaner, RJ, and IPFnet Investigators, . "The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet): diagnostic and adjudication processes." Chest 148, no. 4 (October 2015): 1034-1042. Full Text
  - Vaz Fragoso, CA, McAvay, G, Van Ness, PH, Casaburi, R, Jensen, RL, MacIntyre, N, Gill, TM, Yaggi, HK, and Concato, J. "Phenotype of normal spirometry in an aging population." American journal of respiratory and critical care medicine 192, no. 7 (October 2015): 817-825. Full Text
  - MacIntyre, N. "Take a Deep Breath-or Not." Critical care medicine 43, no. 9 (September 2015): 2021-2022. Full Text
  - Regan, EA, Lynch, DA, Curran-Everett, D, Curtis, JL, Austin, JHM, Grenier, PA, Kauczor, H-U, Bailey, WC, DeMeo, DL, Casaburi, RH, Friedman, P, Van Beek, EJR, Hokanson, JE, Bowler, RP, Beaty, TH, Washko, GR, Han, MK, Kim, V, Kim, SS, Yagihashi, K, Washington, L, McEvoy, CE, Tanner, C, Mannino, DM, Make, BJ, Silverman, EK, Crapo, JD, and Genetic Epidemiology of COPD (COPDGene) Investigators, . "Clinical and Radiologic Disease in Smokers With Normal Spirometry." JAMA internal medicine 175, no. 9 (September 2015): 1539-1549. Full Text
  - Fink, JB, and Macintyre, NR. "Discussion." Respiratory Care 60, no. 6 (June 1, 2015): 790-793.
  - Macintyre, NR, and Fink, JB. "Discussion." Respiratory Care 60, no. 6 (June 1, 2015): 891-893.
  - Grissom, CK, Hirshberg, EL, Dickerson, JB, Brown, SM, Lanspa, MJ, Liu, KD, Schoenfeld, D, Tidswell, M, Hite, RD, Rock, P, Miller, RR, Morris, AH, and National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network, . "Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*." Critical care medicine 43, no. 2 (February 2015): 288-295. Full Text
  - Fink, JB, Macintyre, NR, and Suggett, JA. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 821-824.
  - Fink, JB, and Macintyre, NR. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 874-879.
  - Macintyre, NR, and Fink, JB. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 955-957.
  - Macintyre, NR, and Fink, JB. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 771-773.
  - Macintyre, NR, and Fink, JB. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 847-849.
  - Macintyre, NR. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 802-805.
  - Schell-Chaple, HM, Puntillo, KA, Matthay, MA, Liu, KD, National Heart, Lung, and and Blood Institute Acute Respiratory Distress Syndrome Network, . "Body temperature and mortality in patients with acute respiratory distress syndrome." American journal of critical care : an official publication, American Association of Critical-Care Nurses 24, no. 1 (January 2015): 15-23. Full Text
  - Suggett, JA, Fink, JB, and Macintyre, NR. "Discussion." Respiratory Care 60, no. 6 (January 1, 2015): 830-832.
  - Holland, AE, Spruit, MA, Troosters, T, Puhan, MA, Pepin, V, Saey, D, McCormack, MC, Carlin, BW, Sciurba, FC, Pitta, F, Wanger, J, MacIntyre, N, Kaminsky, DA, Culver, BH, Revill, SM, Hernandes, NA, Andrianopoulos, V, Camillo, CA, Mitchell, KE, Lee, AL, Hill, CJ, and Singh, SJ. "An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease." The European respiratory journal 44, no. 6 (December 2014): 1428-1446. (Review) Full Text
  - Miller, AG, Cappiello, JL, Gentile, MA, Almond, AM, Thalman, JJ, and MacIntyre, NR. "Analysis of radial artery catheter placement by respiratory therapists using ultrasound guidance." Respiratory care 59, no. 12 (December 2014): 1813-1816. Full Text
  - Singh, SJ, Puhan, MA, Andrianopoulos, V, Hernandes, NA, Mitchell, KE, Hill, CJ, Lee, AL, Camillo, CA, Troosters, T, Spruit, MA, Carlin, BW, Wanger, J, Pepin, V, Saey, D, Pitta, F, Kaminsky, DA, McCormack, MC, MacIntyre, N, Culver, BH, Sciurba, FC, Revill, SM, Delafosse, V, and Holland, AE. "An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease." The European respiratory journal 44, no. 6 (December 2014): 1447-1478. (Review) Full Text
  - Wan, ES, Castaldi, PJ, Cho, MH, Hokanson, JE, Regan, EA, Make, BJ, Beaty, TH, Han, MK, Curtis, JL, Curran-Everett, D, Lynch, DA, DeMeo, DL, Crapo, JD, and Silverman, EK. "Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene." Respiratory Research 15, no. 1 (December 2014). Full Text
  - Hobbs, BD, Foreman, MG, Bowler, R, Jacobson, F, Make, BJ, Castaldi, PJ, San José Estépar, R, Silverman, EK, Hersh, CP, and COPDGene Investigators, . "Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease." Annals of the American Thoracic Society 11, no. 9 (November 2014): 1387-1394. Full Text
  - McDonald, M-LN, Cho, MH, Sørheim, I-C, Lutz, SM, Castaldi, PJ, Lomas, DA, Coxson, HO, Edwards, LD, MacNee, W, Vestbo, J, Yates, JC, Agusti, A, Calverley, PMA, Celli, B, Crim, C, Rennard, SI, Wouters, EFM, Bakke, P, Tal-Singer, R, Miller, BE, Gulsvik, A, Casaburi, R, Wells, JM, Regan, EA, Make, BJ, Hokanson, JE, Lange, C, Crapo, JD, Beaty, TH, Silverman, EK, Hersh, CP, and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints and COPDGene Investigators, . "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51, no. 5 (November 2014): 678-687. Full Text
  - Hersh, CP, Make, BJ, Lynch, DA, Barr, RG, Bowler, RP, Calverley, PMA, Castaldi, PJ, Cho, MH, Coxson, HO, DeMeo, DL, Foreman, MG, Han, MK, Harshfield, BJ, Hokanson, JE, Lutz, S, Ramsdell, JW, Regan, EA, Rennard, SI, Schroeder, JD, Sciurba, FC, Steiner, RM, Tal-Singer, R, van Beek, E, Silverman, EK, Crapo, JD, and COPDGene and ECLIPSE Investigators, . "Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus." BMC pulmonary medicine 14 (October 24, 2014): 164-. Full Text
  - Bowler, RP, Kim, V, Regan, E, Williams, AAA, Santorico, SA, Make, BJ, Lynch, DA, Hokanson, JE, Washko, GR, Bercz, P, Soler, X, Marchetti, N, Criner, GJ, Ramsdell, J, Han, MK, Demeo, D, Anzueto, A, Comellas, A, Crapo, JD, Dransfield, M, Wells, JM, Hersh, CP, MacIntyre, N, Martinez, F, Nath, HP, Niewoehner, D, Sciurba, F, Sharafkhaneh, A, Silverman, EK, van Beek, EJR, Wilson, C, Wendt, C, and Wise, RA. "Prediction of acute respiratory disease in current and former smokers with and without COPD." Chest 146, no. 4 (October 2014): 941-950. Full Text
  - MacIntyre, NR. "Tissue hypoxia: implications for the respiratory clinician." Respiratory care 59, no. 10 (October 2014): 1590-1596. (Review) Full Text
  - Sottile, PD, Moss, M, Patel, JJ, Truwit, JD, Sheikh, M, Zimmerman, JL, Diwakar, A, Schmidt, GA, Means, GT, Katz, JN, Desai, AS, MacIntyre, NR, and Poston, JT. "ATS Core Curriculum 2014: Part II. Adult critical care medicine." Annals of the American Thoracic Society 11, no. 8 (October 2014): 1307-1315. (Review) Full Text
  - Lee, JH, Cho, MH, Hersh, CP, McDonald, M-LN, Crapo, JD, Bakke, PS, Gulsvik, A, Comellas, AP, Wendt, CH, Lomas, DA, Kim, V, Silverman, EK, and COPDGene and ECLIPSE Investigators, . "Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease." Respiratory research 15 (September 21, 2014): 113-. Full Text
  - Lee, JH, McDonald, M-LN, Cho, MH, Wan, ES, Castaldi, PJ, Hunninghake, GM, Marchetti, N, Lynch, DA, Crapo, JD, Lomas, DA, Coxson, HO, Bakke, PS, Silverman, EK, Hersh, CP, and COPDGene and ECLIPSE Investigators, . "DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease." Respiratory research 15 (August 20, 2014): 97-. Full Text
  - Wan, ES, Castaldi, PJ, Cho, MH, Hokanson, JE, Regan, EA, Make, BJ, Beaty, TH, Han, MK, Curtis, JL, Curran-Everett, D, Lynch, DA, DeMeo, DL, Crapo, JD, Silverman, EK, and COPDGene Investigators, . "Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene." Respiratory research 15 (August 6, 2014): 89-. Full Text
  - Pathak, V, Welsby, I, Mahmood, K, Wahidi, M, MacIntyre, N, and Shofer, S. "Ventilation and anesthetic approaches for rigid bronchoscopy." Annals of the American Thoracic Society 11, no. 4 (May 2014): 628-634. (Review) Full Text
  - Kim, V, Davey, A, Comellas, AP, Han, MK, Washko, G, Martinez, CH, Lynch, D, Lee, JH, Silverman, EK, Crapo, JD, Make, BJ, Criner, GJ, Farzadegan, H, Bragan, S, Cayetano, S, Curtis, J, Kazerooni, E, Hanania, N, Alapat, P, Bandi, V, Guntupalli, K, Guy, E, Mallampalli, A, Trinh, C, Atik, M, Al-Azzawi, H, Willis, M, Pinero, S, Fahr, L, Nachiappan, A, Bray, C, Frigini, LA, Farinas, C, Katz, D, Freytes, J, Marciel, AM, DeMeo, D, Hersh, C, Jacobson, F, Hatabu, H, Clarke, P, Gill, R, and Hunsaker, A et al. "Clinical and computed tomographic predictors of chronic bronchitis in COPD: A cross sectional analysis of the COPDGene study." Respiratory Research 15, no. 1 (April 27, 2014). Full Text
  - Kim, V, Davey, A, Comellas, AP, Han, MK, Washko, G, Martinez, CH, Lynch, D, Lee, JH, Silverman, EK, Crapo, JD, Make, BJ, Criner, GJ, and COPDGene® Investigators, . "Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study." Respiratory research 15 (April 27, 2014): 52-. Full Text
  - Cho, MH, McDonald, M-LN, Zhou, X, Mattheisen, M, Castaldi, PJ, Hersh, CP, Demeo, DL, Sylvia, JS, Ziniti, J, Laird, NM, Lange, C, Litonjua, AA, Sparrow, D, Casaburi, R, Barr, RG, Regan, EA, Make, BJ, Hokanson, JE, Lutz, S, Dudenkov, TM, Farzadegan, H, Hetmanski, JB, Tal-Singer, R, Lomas, DA, Bakke, P, Gulsvik, A, Crapo, JD, Silverman, EK, Beaty, TH, NETT Genetics, ICGN, and ECLIPSE and COPDGene Investigators, . "Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis." The Lancet. Respiratory medicine 2, no. 3 (March 2014): 214-225. Full Text
  - Swigris, JJ, Streiner, DL, Brown, KK, Belkin, A, Green, KE, Wamboldt, FS, and IPFnet Investigators, . "Assessing exertional dyspnea in patients with idiopathic pulmonary fibrosis." Respiratory medicine 108, no. 1 (January 2014): 181-188. Full Text
  - Matthay, MA, Brower, RG, Carson, S, Douglas, IS, Eisner, M, Hite, D, Holets, S, Kallet, RH, Liu, KD, and MacIntyre, N. "Erratum: Randomized, placebo-controlled clinical trial of an aerosolized β2-agonist for treatment of acute lung injury (American Journal of Respiratory and Critical Care Medicine (2011) 184 (561-568))." American Journal of Respiratory and Critical Care Medicine 188, no. 11 (December 1, 2013): 1378-.
  - Gilstrap, D, and MacIntyre, N. "Patient-ventilator interactions. Implications for clinical management." American journal of respiratory and critical care medicine 188, no. 9 (November 2013): 1058-1068. (Review) Full Text
  - Halaweish, AF, Moon, RE, Foster, WM, Soher, BJ, McAdams, HP, MacFall, JR, Ainslie, MD, MacIntyre, NR, and Charles, HC. "Perfluoropropane gas as a magnetic resonance lung imaging contrast agent in humans." Chest 144, no. 4 (October 2013): 1300-1310. Full Text Link to Item
  - Al-Hegelan, M, and MacIntyre, NR. "Novel modes of mechanical ventilation." Semin Respir Crit Care Med 34, no. 4 (August 2013): 499-507. (Review) Full Text Link to Item
  - Collard, HR, Yow, E, Richeldi, L, Anstrom, KJ, Glazer, C, and IPFnet investigators, . "Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials. (Published online)" Respir Res 14 (July 13, 2013): 73-. Full Text Link to Item
  - MacIntyre, NR. "The ventilator discontinuation process: an expanding evidence base." Respir Care 58, no. 6 (June 2013): 1074-1086. (Review) Full Text Link to Item
  - Scott, JB, Gentile, MA, Bennett, SN, Couture, M, and MacIntyre, NR. "Apnea testing during brain death assessment: a review of clinical practice and published literature." Respir Care 58, no. 3 (March 2013): 532-538. (Review) Full Text Link to Item
  - MacIntyre, N. "Patient-ventilator trigger dys-synchrony: A common phenomenon with important implications." Critical Care 17, no. 3 (2013). Full Text
  - MacIntyre, NR. "Supporting oxygenation in acute respiratory failure." Respir Care 58, no. 1 (January 2013): 142-150. (Review) Full Text Link to Item
  - Macintyre, NR. "Evidence-based assessments in the ventilator discontinuation process." Respir Care 57, no. 10 (October 2012): 1611-1618. (Review) Full Text Link to Item
  - Macintyre, NR. "Chronic critical illness: the growing challenge to health care." Respir Care 57, no. 6 (June 2012): 1021-1027. (Review) Full Text Link to Item
  - Rambod, M, Porszasz, J, Make, BJ, Crapo, JD, Casaburi, R, and COPDGene Investigators, . "Six-minute walk distance predictors, including CT scan measures, in the COPDGene cohort." Chest 141, no. 4 (April 2012): 867-875. Full Text Link to Item
  - Dunne, PJ, MacIntyre, NR, Schmidt, UH, Haas, CF, Rye, KJ-B, Kauffman, GW, and Hess, DR. "Respiratory care year in review 2011: Long-term oxygen therapy, pulmonary rehabilitation, airway management, acute lung injury, education, and management." Respiratory Care 57, no. 4 (2012): 590-606. Full Text
  - Hegewald, MJ, Jensen, RL, Teeter, JG, Wise, RA, Riese, RJ, England, RD, Ahrens, RC, Crapo, RO, and MacIntyre, NR. "Long-term intersession variability for single-breath diffusing capacity." Respiration 84, no. 5 (2012): 377-384. Full Text
  - III, RRM, MacIntyre, NR, Hite, RD, Truwit, JD, Brower, RG, Morris, AH, and Schmidt, GA. "Point: Should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes\No." Chest 141, no. 6 (2012): 1379-1387. Full Text
  - MacIntyre, NR. "Mechanical ventilation in the context of a "bag-in-box" respiratory system." Critical Care Medicine 40, no. 6 (2012): 1988-1989. Full Text
  - MacIntyre, NR. "The future of pulmonary function testing." Respir Care 57, no. 1 (January 2012): 154-161. Full Text Link to Item
  - Martinez, CH, Chen, Y-H, Westgate, PM, Liu, LX, Murray, S, Curtis, JL, Make, BJ, Kazerooni, EA, Lynch, DA, Marchetti, N, Washko, GR, Martinez, FJ, Han, MK, Hanania, N, Alapat, P, Bandi, V, Guntupalli, K, Guy, E, Mallampalli, A, Trinh, C, Atik, M, DeMeo, D, Hersh, C, Jacobson, F, Barr, RG, Thomashow, B, Austin, J, Jr, NM, Washington, L, McAdams, HP, Rosiello, R, Bresnahan, T, McEvoy, C, Tashjian, J, Wise, R, Hansel, N, Brown, R, Diette, G, Casaburi, R, Porszasz, J, Fischer, H, and Budoff, M et al. "Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease." Thorax 67, no. 5 (2012): 399-406. Full Text
  - Shenolikar, S. "Preface." Progress in Molecular Biology and Translational Science 106 (2012): xv-xvii. Full Text
  - Siedlinski, M, Cho, MH, Bakke, P, Gulsvik, A, Lomas, DA, Anderson, W, Kong, X, Rennard, SI, Beaty, TH, Hokanson, JE, Crapo, JD, Silverman, EK, COPDGene Investigators, , and ECLIPSE Investigators, . "Genome-wide association study of smoking behaviours in patients with COPD." Thorax 66, no. 10 (October 2011): 894-902. Full Text Link to Item
  - National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, , Matthay, MA, Brower, RG, Carson, S, Douglas, IS, Eisner, M, Hite, D, Holets, S, Kallet, RH, Liu, KD, MacIntyre, N, Moss, M, Schoenfeld, D, Steingrub, J, and Thompson, BT. "Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury." Am J Respir Crit Care Med 184, no. 5 (September 1, 2011): 561-568. Full Text Link to Item
  - Turner, DA, Williford, WL, Peters, MA, Thalman, JJ, Shearer, IR, Walczak, RJ, Griffis, M, Olson, SA, Sowers, KW, Govert, JA, Macintyre, NR, and Cheifetz, IM. "Development of a collaborative program to provide extracorporeal membrane oxygenation for adults with refractory hypoxemia within the framework of a pandemic." Pediatr Crit Care Med 12, no. 4 (July 2011): 426-430. Full Text Link to Item
  - Macintyre, NR, Nava, S, Diblasi, RM, Restrepo, RD, and Hess, DR. "Respiratory care year in review 2010: part 2. Invasive mechanical ventilation, noninvasive ventilation, pediatric mechanical ventilation, aerosol therapy." Respir Care 56, no. 5 (May 2011): 667-680. (Review) Full Text Link to Item
  - Hess, DR, and MacIntyre, NR. "Ventilator discontinuation: Why are we still weaning?." American Journal of Respiratory and Critical Care Medicine 184, no. 4 (2011): 392-394. Full Text
  - MacIntyre, N. "Airway pressure release ventilation: Hope or hype?." Critical Care Medicine 39, no. 10 (2011): 2376-2377. Full Text
  - MacIntyre, N. "Counterpoint: Is pressure assist-control preferred over volume assist-control mode for lung protective ventilation in patients with ARDS? No." Chest 140, no. 2 (2011): 290-292. Full Text
  - MacIntyre, NR. "Patient-ventilator interactions: optimizing conventional ventilation modes." Respir Care 56, no. 1 (January 2011): 73-84. Full Text Link to Item
  - Marini, JJ, and MacIntyre, N. "Point: Is pressure assist-control preferred over volume assist-control mode for lung protective ventilation in patients with ARDS? Yes - No." Chest 140, no. 2 (2011): 286-294. Full Text
  - Miller, MR, Hankinson, J, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Enright, P, van der Grinten, C, Gustafsson, P, Jensen, R, Macintyre, N, McKay, RT, Pedersen, OF, Pellegrino, R, Viegi, G, and Wanger, J. "Standardisation of lung function testing: the authors' replies to readers' comments." Eur Respir J 36, no. 6 (December 2010): 1496-1498. (Letter) Full Text Link to Item
  - Idiopathic Pulmonary Fibrosis Clinical Research Network, , Zisman, DA, Schwarz, M, Anstrom, KJ, Collard, HR, Flaherty, KR, and Hunninghake, GW. "A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis." N Engl J Med 363, no. 7 (August 12, 2010): 620-628. Full Text Link to Item
  - Unroe, M, and MacIntyre, N. "Evolving approaches to assessing and monitoring patient-ventilator interactions." Curr Opin Crit Care 16, no. 3 (June 2010): 261-268. (Review) Full Text Link to Item
  - Branson, RD, and MacIntyre, NR. "Respiratory care controversies II: 44th journal conference." Respir Care 55, no. 2 (February 2010): 121-. Link to Item
  - MacIntyre, N. "Talk to me! Toward better patient-ventilator communication." Crit Care Med 38, no. 2 (February 2010): 714-715. Full Text Link to Item
  - MacIntyre, NR, and Sessler, CN. "Are there benefits or harm from pressure targeting during lung-protective ventilation?." Respir Care 55, no. 2 (February 2010): 175-180. Link to Item
  - MacIntyre, NR, and Branson, RD. "Respiratory care controversies II." Respir Care 55, no. 1 (January 2010): 34-. Link to Item
  - MacIntyre, NR, and Selecky, PA. "Is there a role for screening spirometry?." Respir Care 55, no. 1 (January 2010): 35-42. (Review) Link to Item
  - Peno-Green, L, Verrill, D, Vitcenda, M, Macintyre, N, Graham, H, and American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), . "Patient and program outcome assessment in pulmonary rehabilitation: an AACVPR statement." J Cardiopulm Rehabil Prev 29, no. 6 (November 2009): 402-410. (Review) Full Text Link to Item
  - Macintyre, NR. "Spirometry for the diagnosis and management of chronic obstructive pulmonary disease." Respir Care 54, no. 8 (August 2009): 1050-1057. Link to Item
  - Panettieri, RA, MacIntyre, N, Sims, M, Kerwin, E, Fogarty, C, Noonan, M, Claus, R, and Andrews, WT. "Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study." Clin Ther 31, no. 8 (August 2009): 1716-1723. Full Text Link to Item
  - MacIntyre, N. "Pulse oximetry in critical care scoring systems." Crit Care Med 37, no. 4 (April 2009): 1505-1506. Full Text Link to Item
  - Dunlap, C. "Foreword." (2009).
  - MacIntyre, NR. "The author responds." Respiratory Care 54, no. 11 (2009): 1500--.
  - MacIntyre, NR. "Spirometry for the diagnosis and management of chronic obstructive pulmonary disease (Respiratory Care (2009) 54, 8, 1050-1057)." Respiratory Care 54, no. 11 (2009): 1501--.
  - MacIntyre, NR. "Mechanisms of functional loss in patients with chronic lung disease." Respir Care 53, no. 9 (September 2008): 1177-1184. (Review) Link to Item
  - MacIntyre, NR. "The 23rd annual New Horizons Symposium. Pulmonary rehabilitation: the expanding evidence base. Foreword." Respir Care 53, no. 9 (September 2008): 1176-. Link to Item
  - Drummond, MB, Schwartz, PF, Duggan, WT, Teeter, JG, Riese, RJ, Ahrens, RC, Crapo, RO, England, RD, Macintyre, NR, Jensen, RL, and Wise, RA. "Intersession variability in single-breath diffusing capacity in diabetics without overt lung disease." Am J Respir Crit Care Med 178, no. 3 (August 1, 2008): 225-232. Full Text Link to Item
  - Lugogo, NL, and MacIntyre, NR. "Life-threatening asthma: pathophysiology and management." Respir Care 53, no. 6 (June 2008): 726-735. Link to Item
  - MacIntyre, NR. "Is there a best way to set positive expiratory-end pressure for mechanical ventilatory support in acute lung injury?." Clin Chest Med 29, no. 2 (June 2008): 233-v. (Review) Full Text Link to Item
  - MacIntyre, NR. "Is there a best way to set tidal volume for mechanical ventilatory support?." Clin Chest Med 29, no. 2 (June 2008): 225-v. (Review) Full Text Link to Item
  - MacIntyre, N, and Huang, YC. "Acute exacerbations and respiratory failure in chronic obstructive pulmonary disease." Proc Am Thorac Soc 5, no. 4 (May 1, 2008): 530-535. (Review) Full Text Link to Item
  - Banner, MJ, Euliano, NR, Macintyre, NR, Layon, AJ, Bonett, S, Gentile, MA, Bshouty, Z, Peters, C, and Gabrielli, A. "Ventilator advisory system employing load and tolerance strategy recommends appropriate pressure support ventilation settings: multisite validation study." Chest 133, no. 3 (March 2008): 697-703. Full Text Link to Item
  - Pellegrino, R, Brusasco, V, Viegi, G, Crapo, RO, Burgos, F, Casaburi, R, Coates, A, van der Grinten, CPM, Gustafsson, P, Hankinson, J, Jensen, R, Johnson, DC, Macintyre, N, McKay, R, Miller, MR, Navajas, D, Pedersen, OF, and Wanger, J. "Definition of COPD: based on evidence or opinion?." Eur Respir J 31, no. 3 (March 2008): 681-682. (Letter) Full Text Link to Item
  - MacIntyre, N. "Ventilator discontinuation process: evidence and guidelines." Crit Care Med 36, no. 1 (January 2008): 329-330. Full Text Link to Item
  - MacIntyre, NR, and Myers, TR. "The authors respond." Respiratory Care 53, no. 7 (2008): 923--.
  - MacIntyre, NR, and Myers, TR. "Meeting the challenges of asthma." Respiratory Care 53, no. 5 (2008): 560--.
  - MacIntyre, NR. "Preface." Clinics in Chest Medicine 29, no. 2 (2008): xiii-. Full Text
  - Wise, RA, Teeter, JG, Jensen, RL, England, RD, Schwartz, PF, Giles, DR, Ahrens, RC, MacIntyre, NR, Riese, RJ, and Crapo, RO. "Standardization of the single-breath diffusing capacity in a multicenter clinical trial." Chest 132, no. 4 (October 2007): 1191-1197. Full Text Link to Item
  - MacIntyre, N. "Discontinuing mechanical ventilatory support." Chest 132, no. 3 (September 2007): 1049-1056. (Review) Full Text Link to Item
  - Yang, L-Y, Huang, Y-CT, and Macintyre, NR. "Patient-ventilator synchrony during pressure-targeted versus flow-targeted small tidal volume assisted ventilation." J Crit Care 22, no. 3 (September 2007): 252-257. Full Text Link to Item
  - Macintyre, N. "Finding signals amidst the noise in pulmonary function testing." Chest 132, no. 2 (August 2007): 367-368. Full Text Link to Item
  - Phua, G-C, and Macintyre, NR. "Inhaled corticosteroids in obstructive airway disease." Respir Care 52, no. 7 (July 2007): 852-858. (Review) Link to Item
  - Cheifetz, IM, and MacIntyre, NR. "Respiratory controversies in the critical care setting. Conference summary." Respir Care 52, no. 5 (May 2007): 636-644. Link to Item
  - Cheifetz, IM, and MacIntyre, NR. "Respiratory controversies in the critical care setting. Part I." Respir Care 52, no. 4 (April 2007): 406-407. Link to Item
  - MacIntyre, NR, and Rubin, BK. "Respiratory therapies in the critical care setting. Should aerosolized antibiotics be administered to prevent or treat ventilator-associated pneumonia in patients who do not have cystic fibrosis?." Respir Care 52, no. 4 (April 2007): 416-421. Link to Item
  - Myers, TR, and MacIntyre, NR. "Respiratory controversies in the critical care setting. Does airway pressure release ventilation offer important new advantages in mechanical ventilator support?." Respir Care 52, no. 4 (April 2007): 452-458. Link to Item
  - Cheifetz, IM, and MacIntyre, NR. "Respiratory controversies in the critical care setting." Respiratory Care 52, no. 5 (2007): 636-644.
  - MacIntyre, N, Crapo, RO, Viegi, G, Johnson, DC, Grinten, CPMVD, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Enright, P, Gustafsson, P, Hankinson, J, Jensen, R, McKay, R, Miller, MR, Navajas, D, Pedersen, OF, Pellegrino, R, and Wanger, J. "Standardisation of the single-breath determination of carbon monoxide uptake in the lung." Revue des Maladies Respiratoires 24, no. 3 C2 (2007): 2S65-2S82.
  - MacIntyre, NR, and Rubin, BK. "Should aerosolized antibiotics be administered to prevent or treat ventilator-associated pneumonia in patients who do not have cystic fibrosis?." Respiratory Care 52, no. 4 (2007): 416-421.
  - McClintock, DE, Ware, LB, Eisner, MD, Wickersham, N, Thompson, BT, Matthay, MA, Wiedemann, HP, Arroliga, AC, Jr, CJF, Jr, JJK, Periz-Trepichio, P, Parsons, PE, Welsh, C, Jr, WJF, MacIntyre, N, Mallatratt, L, Sebastian, M, Davies, J, Dyne, EV, Govert, J, Sevransky, J, Murray, S, Brower, RG, Thompson, D, Fessler, HE, Morris, AH, Clemmer, T, Davis, R, Jr, JO, Weaver, L, Grissom, C, Thomas, F, Gleich, M, Lawton, C, D'Hulst, J, Peerless, JR, Smith, C, Kallet, R, Luce, JM, Gottlieb, J, and Park, P et al. "Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury." American Journal of Respiratory and Critical Care Medicine 175, no. 3 (2007): 256-262. Full Text
  - Miller, MR, Crapo, R, Hankinson, J, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Enright, P, Grinten, CPMVD, Gustafsson, P, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Navajas, D, Pedersen, OF, Pellegrino, R, Viegi, G, and Wanger, J. "General considerations for lung function testing." Revue des Maladies Respiratoires 24, no. 3 C2 (2007): 2S15-2S25.
  - Miller, MR, Hankinson, J, Brusasco, V, Burgo, F, Casaburi, R, Coates, A, Crapo, R, Enright, P, Grinten, CPMVD, Gustafsson, P, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Navajas, D, Pedersen, OF, Pellegrino, R, Viegi, G, and Wanger, J. "Standardisation of spirometry." Revue des Maladies Respiratoires 24, no. 3 C2 (2007): 2S27-2S49.
  - Myers, TR, and MacIntyre, NR. "Does airway pressure release ventilation offer important new advantages in mechanical ventilator support?." Respiratory Care 52, no. 4 (2007): 452-458.
  - Pellegrino, R, Viegi, G, Brusasco, V, Crapo, RO, Burgos, F, Casaburi, R, Coates, A, Grinten, CPMVD, Gustafsson, P, Hankinson, J, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Miller, MR, Navajas, D, Pedersen, OF, and Wanger, J. "Interpretative strategies for lung function tests." Revue des Maladies Respiratoires 24, no. 3 C2 (2007): 2S83-2S108.
  - Wanger, J, Clausen, JL, Coates, A, Pedersen, OF, Brusasco, V, Burgos, F, Casaburi, R, Crapo, R, Enright, P, Grinten, CPMVD, Gustafsson, P, Hankinson, J, Jensen, R, Johnson, D, MacIntyre, N, McKay, R, Miller, MR, Navajas, D, Pellegrino, R, and Viegi, G. "Standardisation of the measurement of lung volumes." Revue des Maladies Respiratoires 24, no. 3 C2 (2007): 2S51-2S64.
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 12, no. 4 (December 1, 2006). Full Text
  - MacIntyre, N. "Discontinuing mechanical ventilatory support: removing positive pressure ventilation vs removing the artificial airway." Chest 130, no. 6 (December 2006): 1635-1636. Full Text Link to Item
  - MacIntyre, N. "Ventilatory Management of ALI/ARDS." Semin Respir Crit Care Med 27, no. 4 (August 2006): 396-403. (Review) Full Text Link to Item
  - MacIntyre, NR. "Muscle dysfunction associated with chronic obstructive pulmonary disease." Respir Care 51, no. 8 (August 2006): 840-847. Link to Item
  - Huang, Y-CT, O'brien, SR, Vredenburgh, J, Folz, RJ, and Macintyre, NR. "Intrabreath analysis of carbon monoxide uptake during exercise in patients at risk for lung injury." Respir Med 100, no. 7 (July 2006): 1226-1233. Full Text Link to Item
  - Nici, L, Donner, C, Wouters, E, Zuwallack, R, Ambrosino, N, Bourbeau, J, Carone, M, Celli, B, Engelen, M, Fahy, B, Garvey, C, Goldstein, R, Gosselink, R, Lareau, S, MacIntyre, N, Maltais, F, Morgan, M, O'Donnell, D, Prefault, C, Reardon, J, Rochester, C, Schols, A, Singh, S, Troosters, T, and ATS/ERS Pulmonary Rehabilitation Writing Committee, . "American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation." Am J Respir Crit Care Med 173, no. 12 (June 15, 2006): 1390-1413. Full Text Link to Item
  - MacIntyre, NR. "Corticosteroid therapy and chronic obstructive pulmonary disease." Respir Care 51, no. 3 (March 2006): 289-296. (Review) Link to Item
  - Roggli, VL, Piantadosi, CA, MacIntyre, NR, Young, SL, Kussin, PS, Steele, MP, Carraway, MS, Welty-Wolf, KE, Govert, JA, McMahon, TJ, Palmer, SM, Sporn, TA, and Ghio, AJ. "Physician subsidies for tobacco advertising." Am J Respir Crit Care Med 173, no. 2 (January 15, 2006): 246-. (Letter) Full Text Link to Item
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 12, no. 4 (2006): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 12, no. 3 (2006): xiii-xiv. Full Text
  - Branson, RD, and MacIntyre, NR. "Humidification and Filtration in Anesthesia and Intensive Care." Respiratory Care Clinics of North America 12, no. 2 (2006): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Polysomnography II." Respiratory Care Clinics of North America 12, no. 1 (2006): xiii-xiv. Full Text
  - McClintock, DE, Starcher, B, Eisner, MD, Thompson, BT, Hayden, DL, Church, GD, Matthay, MA, Wiedemann, HP, Arroliga, AC, Jr, CJF, Jr, JJK, Periz-Trepichio, P, Parsons, PE, Welsh, C, Jr, WJF, MacIntyre, N, Mallatratt, L, Sebastian, M, Davies, J, Dyne, EV, Govert, J, Sevransky, J, Murray, S, Brower, RG, Thompson, D, Fessler, HE, Morris, AH, Clemmer, T, Davis, R, Jr, JO, Weaver, L, Grissom, C, Thomas, F, Gleich, M, Lawton, C, D'Hulst, J, Peerless, JR, Smith, C, Kallet, R, Luce, JM, and Gottlieb, J et al. "Higher urine desmosine levels are associated with mortality in patients with acute lung injury." American Journal of Physiology - Lung Cellular and Molecular Physiology 291, no. 4 (2006): L566-L571. Full Text
  - MacIntyre, NR, Epstein, SK, Carson, S, Scheinhorn, D, Christopher, K, Muldoon, S, and National Association for Medical Direction of Respiratory Care, . "Management of patients requiring prolonged mechanical ventilation: report of a NAMDRC consensus conference." Chest 128, no. 6 (December 2005): 3937-3954. Full Text Link to Item
  - MacIntyre, NR. "Current issues in mechanical ventilation for respiratory failure." Chest 128, no. 5 Suppl 2 (November 2005): 561S-567S. (Review) Full Text Link to Item
  - Pellegrino, R, Viegi, G, Brusasco, V, Crapo, RO, Burgos, F, Casaburi, R, Coates, A, van der Grinten, CPM, Gustafsson, P, Hankinson, J, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Miller, MR, Navajas, D, Pedersen, OF, and Wanger, J. "Interpretative strategies for lung function tests." Eur Respir J 26, no. 5 (November 2005): 948-968. Full Text Link to Item
  - Macintyre, N, Crapo, RO, Viegi, G, Johnson, DC, van der Grinten, CPM, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Enright, P, Gustafsson, P, Hankinson, J, Jensen, R, McKay, R, Miller, MR, Navajas, D, Pedersen, OF, Pellegrino, R, and Wanger, J. "Standardisation of the single-breath determination of carbon monoxide uptake in the lung." Eur Respir J 26, no. 4 (October 2005): 720-735. Full Text Link to Item
  - Wanger, J, Clausen, JL, Coates, A, Pedersen, OF, Brusasco, V, Burgos, F, Casaburi, R, Crapo, R, Enright, P, van der Grinten, CPM, Gustafsson, P, Hankinson, J, Jensen, R, Johnson, D, Macintyre, N, McKay, R, Miller, MR, Navajas, D, Pellegrino, R, and Viegi, G. "Standardisation of the measurement of lung volumes." Eur Respir J 26, no. 3 (September 2005): 511-522. (Review) Full Text Link to Item
  - Miller, MR, Hankinson, J, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Crapo, R, Enright, P, van der Grinten, CPM, Gustafsson, P, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Navajas, D, Pedersen, OF, Pellegrino, R, Viegi, G, Wanger, J, and ATS/ERS Task Force, . "Standardisation of spirometry." Eur Respir J 26, no. 2 (August 2005): 319-338. Full Text Link to Item
  - Ashmore, JA, Emery, CF, Hauck, ER, and MacIntyre, NR. "Marital adjustment among patients with chronic obstructive pulmonary disease who are participating in pulmonary rehabilitation." Heart Lung 34, no. 4 (July 2005): 270-278. Link to Item
  - Miller, MR, Crapo, R, Hankinson, J, Brusasco, V, Burgos, F, Casaburi, R, Coates, A, Enright, P, van der Grinten, CPM, Gustafsson, P, Jensen, R, Johnson, DC, MacIntyre, N, McKay, R, Navajas, D, Pedersen, OF, Pellegrino, R, Viegi, G, Wanger, J, and ATS/ERS Task Force, . "General considerations for lung function testing." Eur Respir J 26, no. 1 (July 2005): 153-161. (Review) Full Text Link to Item
  - MacIntyre, NR. "Ventilator-associated pneumonia: the role of ventilator management strategies." Respir Care 50, no. 6 (June 2005): 766-772. (Review) Link to Item
  - Levy, MM, Abraham, E, Zilberberg, M, and MacIntyre, NR. "A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation." Chest 127, no. 3 (March 2005): 928-935. Full Text Link to Item
  - MacIntyre, NR. "Respiratory mechanics in the patient who is weaning from the ventilator." Respir Care 50, no. 2 (February 2005): 275-286. (Review) Link to Item
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 11, no. 4 (2005): xiii-xiv. Full Text
  - Branson, RD, and MacIntyre, NR. "State-of-the-art respiratory care education." Respiratory Care Clinics of North America 11, no. 3 (2005): xv-xvi. Full Text
  - Branson, RD, and MacIntyre, NR. "Patient-ventilator interaction." Respiratory Care Clinics of North America 11, no. 2 SPEC. ISS. (2005): xiii-xiv. Full Text
  - Branson, RD, and MacIntyre, NR. "Community-acquired pneumonia: An illness with great diversity." Respiratory Care Clinics of North America 11, no. 1 (2005): xiii-xiv. Full Text
  - Dhand, R, and MacIntyre, NR. "Metered-dose inhalers and dry powder inhalers in aerosol therapy." Respiratory Care 50, no. 9 (2005): 1138--.
  - Plankeel, JF, McMullen, B, and MacIntyre, NR. "Exercise outcomes after pulmonary rehabilitation depend on the initial mechanism of exercise limitation among non-oxygen-dependent COPD patients." Chest 127, no. 1 (January 2005): 110-116. Full Text Link to Item
  - MacIntyre, NR. "The "best" tidal volume for managing acute lung injury/acute respiratory distress syndrome." Respir Care Clin N Am 10, no. 3 (September 2004): 309-v. (Review) Full Text Link to Item
  - MacIntyre, NR. "Setting the positive expiratory-end pressure-FIO2 in acute lung injury/acute respiratory distress syndrome." Respir Care Clin N Am 10, no. 3 (September 2004): 301-v. (Review) Full Text Link to Item
  - Brower, RG, Lanken, PN, MacIntyre, N, Matthay, MA, Morris, A, Ancukiewicz, M, Schoenfeld, D, Thompson, BT, National Heart, Lung, and and Blood Institute ARDS Clinical Trials Network, . "Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome." N Engl J Med 351, no. 4 (July 22, 2004): 327-336. Full Text Link to Item
  - MacIntyre, NR. "Evidence-based ventilator weaning and discontinuation." Respir Care 49, no. 7 (July 2004): 830-836. Link to Item
  - MacIntyre, NR, American Association for Respiratory Care, and National Lung Health Education Program, . "The American Association for Respiratory Care and the National Lung Health Education Program: assuring quality in spirometry." Respir Care 49, no. 6 (June 2004): 587-588. Link to Item
  - MacIntyre, NR. "Respiratory system simulations and modeling." Respir Care 49, no. 4 (April 2004): 401-408. (Review) Link to Item
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 10, no. 4 (2004): ix-x. Full Text
  - Branson, RD, and MacIntyre, NR. "Current clinical controversies in respiratory care." Respiratory Care Clinics of North America 10, no. 3 (2004): ix-x. Full Text
  - Branson, RD, and MacIntyre, NR. "Managing respiratory care services." Respiratory Care Clinics of North America 10, no. 2 (2004): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 10, no. 1 (2004): xi-. Full Text
  - Corwin, HL, Gettinger, A, Pearl, RG, Fink, MP, Levy, MM, Abraham, E, MacIntyre, NR, Shabot, MM, Duh, M-S, and Shapiro, MJ. "The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States." Crit Care Med 32, no. 1 (January 2004): 39-52. Full Text Link to Item
  - Jr, NRM. "Chronic Obstructive Pulmonary Disease." Pharmacotherapy 24, no. 5 II (2004): 33S-43S. Full Text
  - MacIntyre, NR. "Chronic obstructive pulmonary disease: emerging medical therapies." Respir Care 49, no. 1 (January 2004): 64-69. (Review) Link to Item
  - Perren, A, Rotta, AT, Brower, R, Morris, A, MacIntyre, N, and Levy, MM. "High versus Low PEEP in ARDS [2] (multiple letters)." New England Journal of Medicine 351, no. 20 (2004): 2128-2129. Full Text
  - Brower, RG, Morris, A, MacIntyre, N, Matthay, MA, Hayden, D, Thompson, T, Clemmer, T, Lanken, PN, Schoenfeld, D, ARDS Clinical Trials Network, National Heart, Lung, and Blood Institute, and National Institutes of Health, . "Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure." Crit Care Med 31, no. 11 (November 2003): 2592-2597. Full Text Link to Item
  - Emery, CF, Shermer, RL, Hauck, ER, Hsiao, ET, and MacIntyre, NR. "Cognitive and psychological outcomes of exercise in a 1-year follow-up study of patients with chronic obstructive pulmonary disease." Health Psychol 22, no. 6 (November 2003): 598-604. Full Text Link to Item
  - MacIntyre, NR, and Foss, CM. "Pulmonary function testing: coding and billing issues." Respir Care 48, no. 8 (August 2003): 786-790. (Review) Link to Item
  - Shapiro, MJ, Gettinger, A, Corwin, HL, Napolitano, L, Levy, M, Abraham, E, Fink, MP, MacIntyre, N, Pearl, RG, and Shabot, MM. "Anemia and blood transfusion in trauma patients admitted to the intensive care unit." J Trauma 55, no. 2 (August 2003): 269-273. Full Text Link to Item
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 9, no. 4 (2003): xv-xvi. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 9, no. 3 (2003): xv-xvi. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 9, no. 2 (2003): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 9, no. 1 (2003): xi-xii. Full Text
  - MacIntyre, NR. "New horizons in respiratory care pulmonary function testing: Updates and answers." Respiratory Care 48, no. 8 (2003): 763--.
  - MacIntyre, NR. "Aerosol delivery through an artificial airway." Respir Care 47, no. 11 (November 2002): 1279-1288. (Review) Link to Item
  - Huang, Y-CT, O'Brien, SR, and MacIntyre, NR. "Intrabreath diffusing capacity of the lung in healthy individuals at rest and during exercise." Chest 122, no. 1 (July 2002): 177-185. Link to Item
  - MacIntyre, NR. "Invasive mechanical ventilation in adults: conference summary." Respir Care 47, no. 4 (April 2002): 508-518. Link to Item
  - MacIntyre, NR. "Setting the frequency-tidal volume pattern." Respir Care 47, no. 3 (March 2002): 266-274. (Review) Link to Item
  - Branson, RD, and MacIntyre, NR. "Long-term ventilatory support, part II." Respiratory Care Clinics of North America 8, no. 4 (2002): xi-xii.
  - Branson, RD, and MacIntyre, NR. "Long-term ventilatory support, part I." Respiratory Care Clinics of North America 8, no. 3 (2002): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Transport of the mechanically ventilated patient." Respiratory Care Clinics of North America 8, no. 1 (2002): ix-x. Full Text
  - Branson, RD, and MacIntyre, NR. "Adjuncts to mechanical ventilation." Respiratory Care Clinics of North America 8, no. 2 (2002): [d]xiii-.
  - Crapo, RO, Casaburi, R, Coates, AL, Enright, PL, MacIntyre, NR, McKay, RT, Johnson, D, Wanger, JS, Zeballos, RJ, Bittner, V, and Mottram, C. "ATS statement: Guidelines for the six-minute walk test." American Journal of Respiratory and Critical Care Medicine 166, no. 1 (2002): 111-117.
  - MacIntyre, NR. "Bringing scientific evidence to the ventilator weaning and discontinuation process: evidence-based practice guidelines." Respir Care 47, no. 1 (January 2002): 29-30. Link to Item
  - MacIntyre, NR. "Diagnosis and management of severe sepsis." International Congress and Symposium Series - Royal Society of Medicine , no. 249 (2002): 17-38.
  - Wiedemann, HP, Arroliga, AC, Komara, J, Denver, VA, Welsh, C, Jr, WJF, MacIntyre, N, Mallatratt, L, Sebastian, M, Sladen, R, Wilcox, C, Brower, RG, Thompson, D, Morris, AH, Clemmer, T, Davis, R, Jr, JO, Lawton, CB, D'Hulst, J, Smith, C, Jefferson, T, Gottlieb, J, Girod, A, Matthay, MA, Daniel, B, Kallet, R, Luce, JM, Gryzner, MA, Abraham, E, Piedalue, F, Kalous, D, Walberg, C, Lockrem, J, McIntyre, R, Parsons, P, Stevens, C, Silverman, HJ, Corral, W, Toews, GB, Arnoldi, D, and Bartlett, RH et al. "Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome." Critical Care Medicine 30, no. 1 (2002): 1-6.
  - MacIntyre, NR, Cook, DJ, Ely, EW, Epstein, SK, Fink, JB, Heffner, JE, Hess, D, Hubmayer, RD, Scheinhorn, DJ, American College of Chest Physicians, , American Association for Respiratory Care, , and American College of Critical Care Medicine, . "Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine." Chest 120, no. 6 Suppl (December 2001): 375S-395S. (Review) Link to Item
  - MacIntyre, NR. "High-frequency jet ventilation." Respir Care Clin N Am 7, no. 4 (December 2001): 599-610. (Review) Link to Item
  - MacIntyre, NR. "Chronic obstructive pulmonary disease management: the evidence base." Respir Care 46, no. 11 (November 2001): 1294-1303. (Review) Link to Item
  - MacIntyre, NR. "Innovations in mechanical ventilation: what are (and what should be) the drivers? The Roger C. Bone Memorial Lecture." Respir Care 46, no. 3 (March 2001): 267-272. Link to Item
  - Hess, DR, and MacIntyre, NR. "Tracheal gas insufflation: overcoming obstacles to clinical implementation." Respir Care 46, no. 2 (February 2001): 198-199. Link to Item
  - MacIntyre, NR. "Intratracheal catheters as drug delivery systems." Respir Care 46, no. 2 (February 2001): 193-197. (Review) Link to Item
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 7, no. 3 (2001): xiii-xiv. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 7, no. 4 (2001): xi-xii. Full Text
  - Branson, RD, and MacIntyre, NR. "Foreword." Respiratory Care Clinics of North America 7, no. 2 (2001): ix-x. Full Text
  - Branson, RD, and MacIntyre, R. "Foreword." Respiratory Care Clinics of North America 7, no. 1 (2001): xi-. Full Text
  - MacIntyre, NR. "Innovations in mechanical ventilation: What are (and what should be) the drivers?." Respiratory Care 46, no. 3 (2001): 267-272.
  - MacIntyre, NR. "Evidence-based guidelines for weaning and discontinuing ventilatory support: A collective task force facilitated by the American college of chest physicians; the American association for respiratory care; and the American college of critical medicine." Chest 120, no. 6 SUPPL. (2001): 375S-395S.
  - McCrory, DC, Brown, C, Gray, RN, Goslin, RE, Kolimaga, JT, MacIntyre, NR, Oddone, EZ, and Matchar, DB. "Management of acute exacerbations of chronic obstructive pulmonary disease." Evid Rep Technol Assess (Summ) , no. 19 (September 2000): 1-4. Link to Item
  - Dolovich, MA, MacIntyre, NR, Anderson, PJ, Camargo, CA, Chew, N, Cole, CH, Dhand, R, Fink, JB, Gross, NJ, Hess, DR, Hickey, AJ, Kim, CS, Martonen, TB, Pierson, DJ, Rubin, BK, and Smaldone, GC. "Consensus statement: aerosols and delivery devices. American Association for Respiratory Care." Respir Care 45, no. 6 (June 2000): 589-596. (Review) Link to Item
  - MacIntyre, NR. "Aerosolized medications for altering lung surface active properties." Respir Care 45, no. 6 (June 2000): 676-683. (Review) Link to Item
  - Angus, DC, Birmingham, MC, Balk, RA, Scannon, PJ, Collins, D, Kruse, JA, Graham, DR, Dedhia, HV, Homann, S, and MacIntyre, N. "E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators." JAMA 283, no. 13 (April 5, 2000): 1723-1730. Link to Item
  - MacIntyre, N. "Of Goldilocks and ventilatory muscle loading." Crit Care Med 28, no. 2 (February 2000): 588-589. (Review) Link to Item
  - MacIntyre, NR. "Oxygen therapy and exercise response in lung disease." Respir Care 45, no. 2 (February 2000): 194-200. (Review) Link to Item
  - MacIntyre, NR. "Long-term oxygen therapy: conference summary." Respir Care 45, no. 2 (February 2000): 237-245. Link to Item
  - Angus, DC, Birmingham, MC, Balk, RA, Scannon, PJ, Collins, D, Kruse, JA, Graham, DR, Dedhia, HV, Homann, S, and Macintyre, N. "E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: A randomized controlled trial." Journal of the American Medical Association 283, no. 13 (2000): 1723-1730.
  - Crapo, RO, Casaburi, R, Coates, AL, Enright, PL, Hankinson, JL, Irvin, CG, MacIntyre, NR, McKay, RT, Wanger, JS, Anderson, SD, Cockcroft, DW, Fish, JE, and Sterk, PJ. "Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999." Am J Respir Crit Care Med 161, no. 1 (January 2000): 309-329. Full Text Link to Item
  - Crapo, RO, Casaburi, R, Coates, AL, Enright, PL, Hankinson, JL, Irvin, CG, MacIntyre, NR, McKay, RT, Wanger, JS, Anderson, SD, Cockcroft, DW, Fish, JE, and Sterk, PJ. "Guidelines for Methacholine and Exercise Challenge Testing - 1999." American Journal of Respiratory and Critical Care Medicine 161, no. 1 (2000): 309-329.
  - Dolovich, MA, MacIntyre, NR, Anderson, PJ, Jr, CCA, Chew, N, Cole, CH, Dhand, R, Fink, JB, Gross, NJ, Hess, DR, Hickey, AJ, Kim, CS, Martonen, TB, Pierson, DJ, Rubin, BK, and Smaldone, GC. "Consensus statement: Aerosols and delivery devices." Respiratory Care 45, no. 6 (2000): 589-596.
  - Dolovich, MB, Macintyre, NR, Anderson, PJ, Camargo, CA, Chew, N, Cole, CH, Dhand, R, Fink, JB, Gross, NJ, Hess, DR, Hickey, AJ, Kim, CS, Martonen, TB, Pierson, DJ, Rubin, BK, and Smaldone, GC. "Consensus statement: aerosols and delivery devices." J Aerosol Med 13, no. 3 (2000): 291-300. Full Text Link to Item
  - Hijazi, MH, and MacIntyre, NR. "Advances in infection control: ventilator-associated pneumonia." Semin Respir Crit Care Med 21, no. 3 (2000): 245-262. Full Text Link to Item
  - MacIntyre, NR. "Mechanical ventilation strategies for lung protection." Semin Respir Crit Care Med 21, no. 3 (2000): 215-222. Full Text Link to Item
  - MacIntyre, NR. "High-frequency ventilation." Semin Respir Crit Care Med 21, no. 3 (2000): 167-173. Full Text Link to Item
  - MacIntyre, NR. "Scope of mechanical ventilation and need for innovations." Seminars in Respiratory and Critical Care Medicine 21, no. 3 (2000): 155-159.
  - MacIntyre, NR. "Preface: Innovations in mechanical ventilation." Seminars in Respiratory and Critical Care Medicine 21, no. 3 (2000): 153-154.
  - McConnell, R, and MacIntyre, NR. "Tracheal gas insufflation." Semin Respir Crit Care Med 21, no. 3 (2000): 211-214. Full Text Link to Item
  - MacIntyre, NR. "Issues in ventilator weaning." Chest 115, no. 4 (April 1999): 1215-1216. (Letter) Link to Item
  - MacIntyre, NR, Helms, M, Wunderink, R, Schmidt, G, and Sahn, SA. "Automated rotational therapy for the prevention of respiratory complications during mechanical ventilation." Respiratory Care 44, no. 12 (1999): 1447-1451.
  - MacIntyre, NR, Manthous, CA, Schmidt, GA, and Hall, JB. "Issues in ventilator weaning [3] (multiple letters)." Chest 115, no. 4 (1999): 1215-1216. Full Text
  - MacIntyre, NR. "High-frequency ventilation." Crit Care Med 26, no. 12 (December 1998): 1955-1956. (Review) Link to Item
  - Emery, CF, Schein, RL, Hauck, ER, and MacIntyre, NR. "Psychological and cognitive outcomes of a randomized trial of exercise among patients with chronic obstructive pulmonary disease." Health Psychol 17, no. 3 (May 1998): 232-240. Link to Item
  - Crouch, R, and MacIntyre, NR. "Pulmonary rehabilitation of the patient with nonobstructive lung disease." Respir Care Clin N Am 4, no. 1 (March 1998): 59-70. (Review) Link to Item
  - Brown, CD, MacIntyre, NR, and Huang, YC. "Diffusing capacity and pulmonary capillary blood flow during maximal exercise." Chest 114, no. 4 SUPPL. (1998): 335S-.
  - MacIntyre, NR. "Mechanical ventilation: The next 50 years." Respiratory Care 43, no. 6 (1998): 490-493.
  - MacIntyre, NR, McConnell, R, Cheng, KC, and Sane, A. "Patient-ventilator flow dyssynchrony: flow-limited versus pressure-limited breaths." Crit Care Med 25, no. 10 (October 1997): 1671-1677. Link to Item
  - MacIntyre, NR. "Ventilatory muscles and mechanical ventilatory support." Crit Care Med 25, no. 7 (July 1997): 1106-1107. Link to Item
  - MacIntyre, NR. "Diffusing capacity of the lung for carbon monoxide." Respir Care Clin N Am 3, no. 2 (June 1997): 221-233. Link to Item
  - Bach, JR, Brougher, P, Hess, DR, Hill, NS, Kacmarek, RM, Kreimer, D, MacIntyre, NR, Pierson, DJ, Rubenfeld, GD, Stoller, JK, Teague, WG, Turner, RE, and Wunderink, RG. "Consensus conference: Noninvasive positive pressure ventilation." Respiratory Care 42, no. 4 (1997): 362-369.
  - MacIntyre, NR, Cheng, KC, and McConnell, R. "Applied PEEP during pressure support reduces the inspiratory threshold load of intrinsic PEEP." Chest 111, no. 1 (January 1997): 188-193. Link to Item
  - Mishoe, SC, and MacIntyre, NR. "Expanding professional roles for respiratory care practitioners." Respiratory Care 42, no. 1 (1997): 71-91.
  - MacIntyre, NR. "New modes of mechanical ventilation." Clin Chest Med 17, no. 3 (September 1996): 411-421. (Review) Link to Item
  - Abou-Shala, N, and MacIntyre, N. "Emergent management of acute asthma." Med Clin North Am 80, no. 4 (July 1996): 677-699. (Review) Link to Item
  - Fulkerson, WJ, MacIntyre, N, Stamler, J, and Crapo, JD. "Pathogenesis and treatment of the adult respiratory distress syndrome." Arch Intern Med 156, no. 1 (January 8, 1996): 29-38. (Review) Link to Item
  - Branson, RD, MacIntyre, NR, Kacmarek, , MacIntyre, NRWTP, East, TD, and Haas, . "Dual-control modes of mechanical ventilation." Respiratory Care 41, no. 4 (1996): 294-305.
  - Jr, WJO, Baker, JP, Dexter, JR, Dozor, AJ, Hess, DR, Kerby, GR, Kushner, PR, Lerner, SD, MacIntyre, NR, Nielson, DW, O'Donnell, AE, Plummer, AL, Smith, LJ, Telatnik, SC, Quinn, T, Mossor, RC, Bently, CL, Powell, RE, and Meddleton, D. "Guidelines for the use of nebulizers in the home and at domiciliary sites: Report of a consensus conference." Chest 109, no. 3 (1996): 814-820.
  - MacIntyre, NR, Lawlor, B, Carstens, D, and Yetsko, D. "Accuracy and precision of a point-of-care blood gas analyzer incorporating optodes." Respiratory Care 41, no. 9 (1996): 800-804.
  - MacIntyre, NR. "What is tracheal pressure-triggering? - And do we need it? Yes! We do need it!." Respiratory Care 41, no. 6 (1996): 524-525.
  - MacIntyre, NR. "Minimizing alveolar stretch injury during mechanical ventilation." Respiratory Care 41, no. 4 (1996): 318-323.
  - Rosenberg, E, and MacIntyre, N. "The 1995 update of recommendations for a standard technique for measuring the single-breath carbon monoxide diffusing capacity (transfer factor) [2]." American Journal of Respiratory and Critical Care Medicine 154, no. 1 (1996): 265-266.
  - Crouch, R, and MacIntyre, N. "Asthma rehabilitation program." Respir Care Clin N Am 1, no. 2 (December 1995): 345-355. (Review) Link to Item
  - MacIntyre, N. "Mechanical ventilation in asthma." Respir Care Clin N Am 1, no. 2 (December 1995): 333-343. (Review) Link to Item
  - MacIntyre, NR. "Efficacy assessment criteria based on risk and cost." Respir Care 40, no. 9 (September 1995): 968-970. (Review) Link to Item
  - Bone, RC, Balk, RA, Fein, AM, Perl, TM, Wenzel, RP, Reines, HD, Quenzer, RW, Iberti, TJ, Macintyre, N, and Schein, RM. "A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group." Crit Care Med 23, no. 6 (June 1995): 994-1006. Link to Item
  - MacIntyre, NR. "Controversies in mechanical ventilation." Contemp Intern Med 7, no. 4 (April 1995): 10-15. Link to Item
  - MacIntyre, NR. "Psychological factors in weaning from mechanical ventilatory support." Respir Care 40, no. 3 (March 1995): 277-281. Link to Item
  - Armstrong, BW, and MacIntyre, NR. "Pressure-controlled, inverse ratio ventilation that avoids air trapping in the adult respiratory distress syndrome." Crit Care Med 23, no. 2 (February 1995): 279-285. Link to Item
  - Bernard, GR, Branson, RD, Brougher, P, Dellinger, RP, DeVries, D, East, TD, Hess, DR, Hill, NS, Kacmarek, RM, Lachmann, B, MacIntyre, NR, Pierson, DJ, Rubenfeld, G, Slutsky, AS, and Tobin, MJ. "Consensus conference III: Assessing innovations in mechanical ventilatory support." Respiratory Care 40, no. 9 (1995): 926-932.
  - Crapo, RO, Hankinson, JL, Irvin, C, MacIntyre, NR, Voter, KZ, Wise, RA, Graham, B, O'Donnell, C, Paoletti, P, Roca, J, and Veigi, G. "Standardization of spirometry: 1994 Update." American Journal of Respiratory and Critical Care Medicine 152, no. 3 (1995): 1107-1136.
  - Crapo, RO, Hankinson, JL, Irvin, C, MacIntyre, NR, Voter, KZ, Wise, RA, and Graham, B. "Single-breath carbon monoxide diffusing capacity (transfer factor): Recommendations for a standard technique-1995 update." American Journal of Respiratory and Critical Care Medicine 152, no. 6 I (1995): 2185-2198.
  - MacIntyre, NR. "Breathing comfort during weaning with two ventilatory modes." Am J Respir Crit Care Med 151, no. 1 (January 1995): 254-255. (Letter) Full Text Link to Item
  - MacIntyre, NR. "Respiratory factors in weaning from mechanical ventilatory support." Respiratory Care 40, no. 3 (1995): 244-248.
  - Weg, JG, Balk, RA, Tharratt, RS, Jenkinson, SG, Shah, JB, Zaccardelli, D, Horton, J, and Pattishall, EN. "Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome." JAMA 272, no. 18 (November 1994): 1433-1438. Full Text
  - Chiang, AA, Steinfeld, A, Gropper, C, and MacIntyre, N. "Demand-flow airway pressure release ventilation as a partial ventilatory support mode: comparison with synchronized intermittent mandatory ventilation and pressure support ventilation." Crit Care Med 22, no. 9 (September 1994): 1431-1437. Link to Item
  - Roggli, VL, Coin, PG, MacIntyre, NR, and Bell, DY. "Asbestos content of bronchoalveolar lavage fluid. A comparison of light and scanning electron microscopic analysis." Acta Cytol 38, no. 4 (July 1994): 502-510. Link to Item
  - Coleman, RE, MacIntyre, N, Snyder, G, Pattishall, E, and Zaccardelli, D. "Aerosol characteristics of 99mTc-pentetic acid (DTPA) and synthetic surfactant (Exosurf)." Chest 105, no. 6 (June 1994): 1765-1769. Link to Item
  - Huang, YC, Helms, MJ, and MacIntyre, NR. "Normal values for single exhalation diffusing capacity and pulmonary capillary blood flow in sitting, supine positions, and during mild exercise." Chest 105, no. 2 (February 1994): 501-508. Link to Item
  - MacIntyre, NR, Gropper, C, and Westfall, T. "Combining pressure-limiting and volume-cycling features in a patient-interactive mechanical breath." Crit Care Med 22, no. 2 (February 1994): 353-357. Link to Item
  - Emery, CF, Hauck, ER, MacIntyre, NR, and Leatherman, NE. "Psychological functioning among middle-aged and older adult pulmonary patients in exercise rehabilitation." Physical and Occupational Therapy in Geriatrics 12, no. 2 (1994): 13-26. Full Text
  - MacIntyre, NR. "Pressure-limited versus volume-cycled breath delivery strategies." Crit Care Med 22, no. 1 (January 1994): 4-5. Link to Item
  - MacIntyre, NR. "Automated lateral rotational therapy in the intensive care unit." Care of the Critically Ill 10, no. 5 (1994): 210+212-210+213.
  - MacIntyre, NR. "Erratum: Building consensus on the use of mechanical ventilation (Chest (1993) 104 (334-335))." Chest 105, no. 2 (1994): 648--.
  - MacIntyre, NR. "Clinically available new strategies for mechanical ventilatory support." Chest 104, no. 2 (August 1993): 560-565. Link to Item
  - MacIntyre, NR. "Building consensus on the use of mechanical ventilation." Chest 104, no. 2 (August 1993): 334-335. Link to Item
  - Hazinski, MF, Iberti, TJ, MacIntyre, NR, Parker, MM, Tribett, D, Prion, S, and Chmel, H. "Epidemiology, pathophysiology and clinical presentation of gram-negative sepsis." Am J Crit Care 2, no. 3 (May 1993): 224-235. (Review) Link to Item
  - Thalman, JJ, Rinaldo-Gallo, S, and MacIntyre, NR. "Analysis of an endotracheal intubation service provided by respiratory care practitioners." Respir Care 38, no. 5 (May 1993): 469-473. Link to Item
  - Reihsaus, E, Innis, M, MacIntyre, N, and Liggett, SB. "Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects." Am J Respir Cell Mol Biol 8, no. 3 (March 1993): 334-339. Full Text Link to Item
  - MacIntyre, NR. "Pressure support: Coming of age." Seminars in Respiratory Medicine 14, no. 4 (1993): 293-298.
  - Huang, YC, and Macintyre, NR. "Real-time gas analysis improves the measurement of single-breath diffusing capacity." Am Rev Respir Dis 146, no. 4 (October 1992): 946-950. Full Text Link to Item
  - MacIntyre, NR, and Day, S. "Essentials for ventilator-alarm systems." Respir Care 37, no. 9 (September 1992): 1108-1112. (Review) Link to Item
  - Day, SL, Wooton, L, and MacIntyre, N. "Rapid analysis of exhaled CO₂ to assess endotracheal tube placement." Respiratory Care 37, no. 10 (1992): 1161-1165.
  - Emery, CF, Leatherman, NE, Burker, EJ, and MacIntyre, NR. "Psychological outcomes of a pulmonary rehabilitation program." Chest 100, no. 3 (September 1991): 613-617. Link to Item
  - Greenman, RL, Schein, RM, Martin, MA, Wenzel, RP, MacIntyre, NR, Emmanuel, G, Chmel, H, Kohler, RB, McCarthy, M, and Plouffe, J. "A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group." JAMA 266, no. 8 (August 28, 1991): 1097-1102. Link to Item
  - Greenman, RL. "A Controlled Clinical Trial of E5 Murine Monoclonal IgM Antibody to Endotoxin in the Treatment of Gram-Negative Sepsis." JAMA: The Journal of the American Medical Association 266, no. 8 (August 28, 1991): 1097-1097. Full Text
  - Banner, MJ, Kirby, RR, and MacIntyre, NR. "Patient and ventilator work of breathing and ventilatory muscle loads at different levels of pressure support ventilation." Chest 100, no. 2 (August 1991): 531-533. (Review) Link to Item
  - MacIntyre, NR, and Ho, LI. "Effects of initial flow rate and breath termination criteria on pressure support ventilation." Chest 99, no. 1 (January 1991): 134-138. Link to Item
  - Sherman, CR, Fernandez, H, MacIntyre, N, and Brougher, P. "ICN spokesmen emphasize virazole (ribavirin) efficacy and safety [1]." Respiratory Care 36, no. 12 (1991): 1439-1441.
  - MacIntyre, N, Nishimura, M, Usada, Y, Tokioka, H, Takezawa, J, and Shimada, Y. "The Nagoya conference on system design and patient-ventilator interactions during pressure support ventilation." Chest 97, no. 6 (June 1990): 1463-1466. Link to Item
  - MacIntyre, NR. "Importance of trigger sensitivity to ventilator response delay in advanced chronic obstructive pulmonary disease with respiratory failure." Crit Care Med 18, no. 5 (May 1990): 581-582. (Letter) Link to Item
  - MacIntyre, NR, and Leatherman, NE. "Ventilatory muscle loads and the frequency-tidal volume pattern during inspiratory pressure-assisted (pressure-supported) ventilation." Am Rev Respir Dis 141, no. 2 (February 1990): 327-331. Full Text Link to Item
  - Gray, JE, MacIntyre, NR, and Kronenberger, WG. "The effects of bolus normal-saline instillation in conjunction with endotracheal suctioning." Respiratory Care 35, no. 8 (1990): 785-790.
  - MacIntyre, NR. "Pressure support ventilation." Problems in Critical Care 4, no. 2 (1990): 225-231.
  - MacIntyre, NR. "Respiratory monitoring without machinery." Respiratory Care 35, no. 6 (1990): 546-556.
  - Macintyre, NR, and Leatherman, NE. "Ventilatory muscle loads and the frequency-tidal volume pattern during inspiratory pressure-assisted (pressure-supported) ventilation." American Review of Respiratory Disease 141, no. 2 I (1990): 327-331.
  - MacIntyre, NR. "Oxygen uptake and mechanical ventilation." Chest 96, no. 2 (August 1989): 446-447. (Letter) Link to Item
  - Bergin, CJ, Bell, DY, Coblentz, CL, Chiles, C, Gamsu, G, MacIntyre, NR, Coleman, RE, and Putman, CE. "Sarcoidosis: correlation of pulmonary parenchymal pattern at CT with results of pulmonary function tests." Radiology 171, no. 3 (June 1989): 619-624. Full Text Link to Item
  - MacIntyre, NR, and Leatherman, NE. "Mechanical loads on the ventilatory muscles. A theoretical analysis." Am Rev Respir Dis 139, no. 4 (April 1989): 968-973. Full Text Link to Item
  - MacIntyre, NR, and Leatherman, NE. "Mechanical loads on the ventilatory muscles. A theoretical analysis." American Review of Respiratory Disease 139, no. 4 I (1989): 968-973.
  - MacIntyre, NR. "Diffusing capacity of the lung for carbon monoxide." Respiratory Care 34, no. 6 (1989): 489-499.
  - Marini, JJ, Roussos, CS, Marini, JJ, Tobin, MJ, MacIntyre, NR, Belman, MJ, and Moxham, J. "Weaning from mechanical ventilation." Am Rev Respir Dis 138, no. 4 (October 1988): 1043-1046. Link to Item
  - MacIntyre, NR. "New forms of mechanical ventilation in the adult." Clin Chest Med 9, no. 1 (March 1988): 47-54. (Review) Link to Item
  - MacIntyre, NR. "Weaning from mechanical ventilatory support: Volume-assisting intermittent breaths versus pressure-assisting every breath." Respiratory Care 33, no. 2 (1988): 121-125.
  - MacIntyre, NR. "Does positive end-expiratory pressure (PEEP) affect the natural history of acute lung injury?..Yes!." Respiratory Care 33, no. 6 (1988): 487-492.
  - Ramage, JE, Coleman, RE, and MacIntyre, NR. "Rest and exercise cardiac output and diffusing capacity assessed by a single slow exhalation of methane, acetylene, and carbon monoxide." Chest 92, no. 1 (July 1987): 44-50. Link to Item
  - MacIntyre, NR, Ramage, JE, and Follett, JV. "Jet ventilation in support of fiberoptic bronchoscopy." Crit Care Med 15, no. 4 (April 1987): 303-307. Link to Item
  - MacIntyre, NR. "Pressure support ventilation: Effects on ventilatory reflexes and ventilatory-muscle workloads." Respiratory Care 32, no. 6 (1987): 447-453.
  - MacIntyre, NR, Follett, JV, Deitz, JL, and Lawlor, BR. "Jet ventilation at 100 breaths per minute in adult respiratory failure." Am Rev Respir Dis 134, no. 5 (November 1986): 897-901. Full Text Link to Item
  - MacIntyre, NR. "Respiratory function during pressure support ventilation." Chest 89, no. 5 (May 1986): 677-683. Link to Item
  - MacIntyre, NR, Leatherman, N, Deitz, JL, Wagoner, R, and Friedman, M. "Distribution and uptake of helium, carbon monoxide, and acetylene in the lungs during high frequency oscillatory ventilation." Respir Physiol 63, no. 2 (February 1986): 201-212. Link to Item
  - MacIntyre, NR, Silver, RM, Miller, CW, Schuler, F, and Coleman, RE. "Aerosol delivery in intubated, mechanically ventilated patients." Crit Care Med 13, no. 2 (February 1985): 81-84. Link to Item
  - Harlan, WR, Cowie, CC, Oberman, A, Mitchell, RE, and MacIntyre, NR. "Prediction of subsequent ischemic heart disease using serial resting electrocardiograms." Am J Epidemiol 119, no. 2 (February 1984): 208-217. Link to Item
  - Lawlor, BR, Anderson, HR, and MacIntyre, NR. "Accuracy and precision of arterial blood gas measurements from the AVL 940 microsample analyzer." Respiratory Care 29, no. 10 (1984): 1006-1008.
  - MacIntyre, NR, Deitz, JL, Lawlor, BR, and Nagy, RS. "DETERMINANTS OF ARTERIAL OXYGENATION DURING VENTILATION WITH A HIGH FREQUENCY JET VENTILATOR." (1984): 50--.
  - Osgood, CF, Watson, MH, Slaughter, MS, and MacIntyre, NR. "Hemodynamic monitoring in respiratory care." Respir Care 29, no. 1 (January 1984): 25-34. Link to Item
  - MacIntyre, NR, Anderson, HR, Silver, RM, Schuler, FR, and Coleman, RE. "Pulmonary function in mechanically-ventilated patients during 24-hour use of a hygroscopic condensor humidifier." Chest 84, no. 5 (November 1983): 560-564. Link to Item
  - MacIntyre, NR, and Nadel, JA. "Regional diffusing capacity in normal lungs during a slow exhalation." J Appl Physiol Respir Environ Exerc Physiol 52, no. 6 (June 1982): 1487-1492. Full Text Link to Item
  - Stokes, DL, MacIntyre, NR, and Nadel, JA. "Nonlinear increases in diffusing capacity during exercise by seated and supine subjects." J Appl Physiol Respir Environ Exerc Physiol 51, no. 4 (October 1981): 858-863. Full Text Link to Item
  - MacIntyre, NR, Kunkler, JR, Mitchell, RE, Oberman, A, and Graybiel, A. "Eight-year follow-up of exercise electrocardiograms in healthy, middle-aged aviators." Aviat Space Environ Med 52, no. 4 (April 1981): 256-259. Link to Item
  - MacIntyre, NR, Mitchell, RE, Oberman, A, Harlan, WR, and Graybiel, A. "Long-term follow-up of lung volume measurements in initially healthy young aviators." Aviat Space Environ Med 52, no. 1 (January 1981): 1-5. Link to Item
  - MacIntyre, NR, Mitchell, RE, Oberman, A, Harlan, WR, Graybiel, A, and Johnson, E. "Longevity in military pilots: 37-year followup of the Navy's "1000 aviators"." Aviat Space Environ Med 49, no. 9 (September 1978): 1120-1122. Link to Item
- Other Articles
  - Kim, WJ, Silverman, EK, Hoffman, E, Criner, GJ, Mosenifar, Z, Sciurba, FC, Make, BJ, Carey, V, Estépar, RSJ, Diaz, A, Reilly, JJ, Martinez, FJ, Washko, GR, Fishman, AP, Bozzarello, BA, Al-Amin, A, Katz, M, Wheeler, C, Baker, E, Barnard, P, Cagle, P, Carter, J, Chatziioannou, S, Conejo-Gonzales, K, Dubose, K, Haddad, J, Hicks, D, Kleiman, N, Milburn-Barnes, M, Nguyen, C, Reardon, M, Reeves-Viets, J, Sax, S, Sharafkhaneh, A, Wilson, O, Young, C, Espada, R, Butanda, R, Ellisor, M, Fox, P, and Hale, K et al. "CT metrics of airway disease and emphysema in severe COPD." Chest 136, no. 2 (2009): 396-404. Full Text
Teaching & Mentoring
Recent Courses
- MEDICINE 430C: Pulmonary Medicine 2016

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Book Sections

Conference Papers

Journal Articles

Other Articles

Recent Courses