Scholars@Duke
Manju Liu

Manju Liu

Assistant Professor of Medical Physics at Duke Kunshan University
DKU Faculty

Selected Publications

Assessing global and regional iron content in deep gray matter as a function of age using susceptibility mapping.

Journal Article Journal of magnetic resonance imaging : JMRI · July 2016 PurposeTo investigate the correlation of non-heme iron content in deep gray matter nuclei as a function of age using quantitative susceptibility mapping (QSM) from both whole-structural and regional perspectives.Materials and methodsWe st ... Full text Cite

Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2.

Journal Article Magnetic resonance imaging · June 2015 PurposeTo evaluate the sensitivity and specificity of quantitative magnetic resonance (MR) iron mapping including R2, R2* and magnetic susceptibility to differentiate patients with Parkinson's disease (PD) from healthy controls.Materials and m ... Full text Cite

Patterns of chronic venous insufficiency in the dural sinuses and extracranial draining veins and their relationship with white matter hyperintensities for patients with Parkinson's disease.

Journal Article Journal of vascular surgery · June 2015 BackgroundIdiopathic Parkinson's disease (IPD) remains one of those neurodegenerative diseases for which the cause remains unknown. Many clinically diagnosed cases of IPD are associated with cerebrovascular disease and white matter hyperintensitie ... Full text Cite

Iron accumulation is not homogenous among patients with Parkinson's disease

Journal Article Parkinson S Disease · January 1, 2015 Background. Iron is considered to lead to neurodegeneration and has been hypothesized as a possible cause of Parkinson's disease (PD). Susceptibility-weighted imaging (SWI) is a powerful tool to measure phase related iron content of brain. Methods. Twelve ... Full text Cite

Evaluation of the deformation and corresponding dosimetric implications in prostate cancer treatment.

Journal Article Physics in medicine and biology · September 2012 The cone-beam computed tomography (CBCT) imaging modality is an integral component of image-guided adaptive radiation therapy (IGART), which uses patient-specific dynamic/temporal information for potential treatment plan modification. In this study, an off ... Full text Cite

Value of magnetic resonance imaging for nodal staging in patients with head and neck squamous cell carcinoma: a meta-analysis.

Journal Article Academic radiology · March 2012 ObjectivesTo evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting lymph node metastases in patients with head and neck squamous cell carcinoma (HNSCC).MethodsMEDLINE, EMBASE, the CBM disc databases, and other ... Full text Cite

Different iron-deposition patterns of multiple system atrophy with predominant parkinsonism and idiopathetic Parkinson diseases demonstrated by phase-corrected susceptibility-weighted imaging.

Journal Article AJNR. American journal of neuroradiology · February 2012 Background and purposeMSA-P and IPD have similar clinical presentations that may complicate accurate clinical diagnosis. Different iron-deposition patterns of those 2 diseases have been demonstrated in histopathology. The aim was to demonstrate th ... Full text Cite

Assessing abnormal iron content in the deep gray matter of patients with multiple sclerosis versus healthy controls.

Journal Article AJNR. American journal of neuroradiology · February 2012 Background and purposeIt is well known that patients with MS tend to have abnormal iron deposition in and around the MS plaques, in the basal ganglia and the THA. In this study, we used SWI to quantify iron content in patients with MS and healthy ... Full text Cite

Diagnostic value of diffusion-weighted magnetic resonance imaging compared with fluorodeoxyglucose positron emission tomography/computed tomography for pancreatic malignancy: A meta-analysis using a hierarchical regression model

Journal Article Journal of Gastroenterology and Hepatology Australia · January 1, 2012 Background and Aim: To obtain diagnostic performance of diffusion-weighted magnetic resonance imaging (DWI) and fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the detection of pancreatic malignancy. Method ... Full text Cite

Correlation of putative iron content as represented by changes in R2* and phase with age in deep gray matter of healthy adults.

Journal Article Journal of magnetic resonance imaging : JMRI · September 2010 PurposeTo establish a correlation between putative iron content using susceptibility weighted imaging (SWI) phase and T2* weighted magnitude values in the basal ganglia and the thalamus as a function of age in healthy human brains.Materials an ... Full text Cite

Iron stores and cerebral veins in MS studied by susceptibility weighted imaging.

Journal Article International angiology : a journal of the International Union of Angiology · April 2010 AimIn this paper, we seek to determine whether the iron deposition as seen by susceptibility weighted imaging (SWI) in the basal ganglia and thalamus of patients with multiple sclerosis is greater than the iron content measured in normal subjects ... Cite