Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Resident, Surgery, Duke University 1991 - 1998
  • M.D., University of Wisconsin - Madison 1991
• 

  Previous Appointments & Affiliations

  • Associate Professor of Surgery, Surgical Oncology, Surgery 2009 - 2015
  • Associate Professor of Surgery, Surgery, Clinical Science Departments 2004 - 2009
  • Assistant Professor of Surgery, Surgery, Clinical Science Departments 1999 - 2004
• Research
• 

  Selected Grants

  • Inhibition of CaMKK2 sensitizes rectal cancers to radiation therapy awarded by National Institutes of Health 2021 - 2022
  • Prevention of Surgical Site Infection using Statistical Process Control Charts awarded by Agency for Healthcare Research and Quality 2015 - 2020
  • A Randomized, Double-blind, Placebo Controlled Efficacy, Safety, and Tolerability Study of up to 20 mL of DFA-02 in Patients Undergoing Abdominal Surgery awarded by Dr. Reddy's Laboratories Ltd. 2014 - 2016
  • Cancer Control Using Message Framing to Promote Physical Activity in Colorectal Cancer Survivors awarded by National Institutes of Health 2008 - 2012
  • Coherence Imaging for Assessing Colorectal Neoplasia awarded by National Institutes of Health 2009 - 2012
  • Effects of Short Chain Fatty Acids on Colonic Motility awarded by National Institutes of Health 2005 - 2007
  • Cancer Care Quality Measures: Diagnosis and Treatment of Colorectal Cancer awarded by Agency for Healthcare Research and Quality 2004 - 2005
• 

  External Relationships

  • Becton, Dickinson and Company
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Cooper, H. J., D. P. Singh, A. Gabriel, C. Mantyh, R. Silverman, and L. Griffin. “Closed Incision Negative Pressure Therapy versus Standard of Care in Reduction of Surgical Site Complications: A Systematic Review and Meta-analysis.” Plastic and Reconstructive Surgery  Global Open 11, no. 3 (March 16, 2023). https://doi.org/10.1097/GOX.0000000000004722.
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    • Seidelman, Jessica L., Christopher R. Mantyh, and Deverick J. Anderson. “Surgical Site Infection Prevention: A Review.” Jama 329, no. 3 (January 17, 2023): 244–52. https://doi.org/10.1001/jama.2022.24075.
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    • Baker, Arthur W., Iulian Ilieş, James C. Benneyan, Yuliya Lokhnygina, Katherine R. Foy, Sarah S. Lewis, Brittain Wood, et al. “Early recognition and response to increases in surgical site infections using optimised statistical process control charts-The early 2RIS trial: A multicentre stepped wedge cluster randomised controlled trial.” Eclinicalmedicine 54 (December 2022): 101698. https://doi.org/10.1016/j.eclinm.2022.101698.
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    • PelvEx Collaborative, Camille P. “Minimum standards of pelvic exenterative practice: PelvEx Collaborative guideline.” Br J Surg 109, no. 12 (November 22, 2022): 1251–63. https://doi.org/10.1093/bjs/znac317.
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    • Krischak, Madison K., Joshua P. Hayden, Kevin Krughoff, Brian M. Inouye, William R. Boysen, Christopher R. Mantyh, Detlev Erdmann, and Andrew C. Peterson. “Patient-Reported and Physiologic Outcomes Following Pelvic Exenteration for Non-Repairable Radiated Rectourethral Fistula.” Urology 166 (August 2022): 257–63. https://doi.org/10.1016/j.urology.2022.03.041.
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    • Lam, Sean Shao Wei, Hamed Zaribafzadeh, Boon Yew Ang, Wendy Webster, Daniel Buckland, Christopher Mantyh, and Hiang Khoon Tan. “Estimation of Surgery Durations Using Machine Learning Methods-A Cross-Country Multi-Site Collaborative Study.” Healthcare (Basel) 10, no. 7 (June 25, 2022). https://doi.org/10.3390/healthcare10071191.
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    • Turley, Megan C., Carrie Moore, John M. Creasy, Jeremy Sharib, Billy Lan, Julie K. M. Thacker, John Migaly, et al. “Combined Primary Resection with Hepatic Artery Infusion Pump Implantation Is Safe for Unresectable Colorectal Liver Metastases.” J Gastrointest Surg 26, no. 4 (April 2022): 764–71. https://doi.org/10.1007/s11605-021-05195-8.
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    • Berger, Miles, Jeffrey N. Browndyke, Mary Cooter Wright, Chloe Nobuhara, Melody Reese, Leah Acker, W Michael Bullock, et al. “Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.” Ann Clin Transl Neurol 9, no. 2 (February 2022): 155–70. https://doi.org/10.1002/acn3.51499.
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    • Ruiz-Tovar, Jaime, Marja A. Boermeester, Liliana Bordeianou, George J. Chang, Emre Gorgun, Christoph Justinger, Elise H. Lawson, et al. “Delphi Consensus on Intraoperative Technical/Surgical Aspects to Prevent Surgical Site Infection after Colorectal Surgery.” J Am Coll Surg 234, no. 1 (January 1, 2022): 1–11. https://doi.org/10.1097/XCS.0000000000000022.
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    • Browndyke, Jeffrey N., Mary C. Wright, Rosa Yang, Ayesha Syed, John Park, Ashley Hall, Katherine Martucci, et al. “Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study.” Br J Anaesth 127, no. 6 (December 2021): 917–28. https://doi.org/10.1016/j.bja.2021.08.012.
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    • PelvEx Collaborative, P. P. “Induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer: study protocol of a multicentre, open-label, parallel-arms, randomized controlled study (PelvEx II).” Bjs Open 5, no. 3 (May 7, 2021). https://doi.org/10.1093/bjsopen/zrab029.
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    • Freischlag, Kyle, L. Olivere, M. Turner, M. Adam, C. Mantyh, and J. Migaly. “Does Fragmentation of Care in Locally Advanced Rectal Cancer Increase Patient Mortality?” J Gastrointest Surg 25, no. 5 (May 2021): 1287–96. https://doi.org/10.1007/s11605-020-04760-x.
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    • Terrando, Niccolò, John J. Park, Michael Devinney, Cliburn Chan, Mary Cooter, Pallavi Avasarala, Joseph P. Mathew, et al. “Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.” Sci Rep 11, no. 1 (February 4, 2021): 3047. https://doi.org/10.1038/s41598-021-82606-5.
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    • PelvEx Collaborative, Elihu. “Perioperative management and anaesthetic considerations in pelvic exenterations using Delphi methodology: results from the PelvEx Collaborative.” Bjs Open 5, no. 1 (January 8, 2021). https://doi.org/10.1093/bjsopen/zraa055.
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    • Gilmore, Brian, Mohamed A. Adam, Kristen Rhodin, Megan C. Turner, Brian Ezekian, Christopher R. Mantyh, and John Migaly. “Evolution of minimally invasive surgery for rectal cancer: update from the national cancer database.” Surg Endosc 35, no. 1 (January 2021): 275–90. https://doi.org/10.1007/s00464-020-07393-y.
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    • VanDusen, Keith W., Yi-Ju Li, Victor Cai, Ashley Hall, Sarah Hiles, J Will Thompson, M Arthur Moseley, et al. “Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.” J Alzheimers Dis 80, no. 3 (2021): 1281–97. https://doi.org/10.3233/JAD-201544.
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    • PelvEx Collaborative, Xin. “Predicting outcomes of pelvic exenteration using machine learning.” Colorectal Dis 22, no. 12 (December 2020): 1933–40. https://doi.org/10.1111/codi.15235.
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    • Somarelli, Jason A., Roham Salman Roghani, Ali Sanjari Moghaddam, Beatrice C. Thomas, Gabrielle Rupprecht, Kathryn E. Ware, Erdem Altunel, et al. “A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.” Mol Cancer Ther 19, no. 12 (December 2020): 2516–27. https://doi.org/10.1158/1535-7163.MCT-20-0454.
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    • PelvEx Collaborative, Aparna S. “Simultaneous pelvic exenteration and liver resection for primary rectal cancer with synchronous liver metastases: results from the PelvEx Collaborative.” Colorectal Dis 22, no. 10 (October 2020): 1258–62. https://doi.org/10.1111/codi.15064.
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    • PelvEx Collaborative, D. C. “The impact of the COVID-19 pandemic on the Management of Locally Advanced Primary/Recurrent Rectal Cancer.” Br J Surg 107, no. 11 (October 2020): e547–48. https://doi.org/10.1002/bjs.11893.
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    • PelvEx Collaborative, Gil I. “The global cost of pelvic exenteration: in-hospital perioperative costs.” Br J Surg 107, no. 11 (October 2020): e470–71. https://doi.org/10.1002/bjs.11924.
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    • PelvEx Collaborative, Daniela. “Management strategies for patients with advanced rectal cancer and liver metastases using modified Delphi methodology: results from the PelvEx Collaborative.” Colorectal Dis 22, no. 9 (September 2020): 1184–88. https://doi.org/10.1111/codi.15007.
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    • Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.
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    • Turner, M. C., O. Jawitz, M. A. Adam, E. Srinivasan, D. Niedzwiecki, J. Migaly, D. A. Fisher, and C. R. Mantyh. “Comparison of survival of stage I-III colon cancer by travel distance and hospital volume.” Tech Coloproctol 24, no. 7 (July 2020): 703–10. https://doi.org/10.1007/s10151-020-02207-8.
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    • Aronson, Solomon, Gavin Martin, Padma Gulur, Mike E. Lipkin, Sandhya A. Lagoo-Deenadayalan, Christopher R. Mantyh, David E. Attarian, Joseph P. Mathew, and Allan D. Kirk. “Preoperative Optimization: A Continued Call to Action.” Anesth Analg 130, no. 4 (April 2020): 808–10. https://doi.org/10.1213/ANE.0000000000004492.
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    • Aronson, Solomon, Sutton Murray, Gavin Martin, Jeanna Blitz, Timothy Crittenden, Mike E. Lipkin, Christopher R. Mantyh, et al. “Roadmap for Transforming Preoperative Assessment to Preoperative Optimization.” Anesth Analg 130, no. 4 (April 2020): 811–19. https://doi.org/10.1213/ANE.0000000000004571.
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    • VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.
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    • Berger, Miles, David M. Murdoch, Janet S. Staats, Cliburn Chan, Jake P. Thomas, Grant E. Garrigues, Jeffrey N. Browndyke, et al. “Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.” Anesth Analg 129, no. 5 (November 2019): e150–54. https://doi.org/10.1213/ANE.0000000000004179.
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    • Raman, Vignesh, Mohamed A. Adam, Megan C. Turner, Harvey G. Moore, Christopher R. Mantyh, and John Migaly. “Disparity of Colon Cancer Outcomes in Rural America: Making the Case to Travel the Extra Mile.” J Gastrointest Surg 23, no. 11 (November 2019): 2285–93. https://doi.org/10.1007/s11605-019-04270-5.
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    • PelvEx Collaborative, Patricia. “Palliative pelvic exenteration: A systematic review of patient-centered outcomes.” Eur J Surg Oncol 45, no. 10 (October 2019): 1787–95. https://doi.org/10.1016/j.ejso.2019.06.011.
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    • Turner, M. C., D. Becerra, Z. Sun, J. Watson, K. Leung, J. Migaly, C. R. Mantyh, and D. G. Blazer. “The side of the primary tumor affects overall survival in colon adenocarcinoma: an analysis of the national cancer database.” Tech Coloproctol 23, no. 6 (June 2019): 537–44. https://doi.org/10.1007/s10151-019-01997-w.
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    • Turner, M. C., M. D. Talbott, C. Reed, Z. Sun, M. L. Cox, B. Ezekian, K. L. Sherman, C. R. Mantyh, and J. Migaly. “Disparities in colostomy reversal after Hartmann's procedure for diverticulitis.” Tech Coloproctol 23, no. 5 (May 2019): 445–51. https://doi.org/10.1007/s10151-019-01995-y.
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    • Turner, Megan C., Shay L. Behrens, Wendy Webster, Kirk Huslage, Becky A. Smith, Rebekah Wrenn, Regina Woody, and Christopher R. Mantyh. “Multidisciplinary Approach to Clostridium difficile Infection in Adult Surgical Patients.” J Am Coll Surg 228, no. 4 (April 2019): 570–80. https://doi.org/10.1016/j.jamcollsurg.2018.12.045.
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    • Kokosis, George, Brett T. Phillips, Joanne Soo, Luke Poveromo, Detlev Erdmann, Christopher R. Mantyh, John Migaly, and Howard Levinson. “Modified V-Y Fasciocutaneous Flap Reconstruction After Abdominoperineal Resection in Irradiated Patients Prevents Wound Dehiscence and Associated Complications: A Retrospective Analysis and Benchtop Confirmation.” Ann Plast Surg 82, no. 2 (February 2019): 218–23. https://doi.org/10.1097/SAP.0000000000001672.
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    • Freischlag, K., M. Adam, M. Turner, J. Watson, B. Ezekian, P. M. Schroder, C. Mantyh, and J. Migaly. “With widespread adoption of MIS colectomy for colon cancer, does hospital type matter?” Surg Endosc 33, no. 1 (January 2019): 159–68. https://doi.org/10.1007/s00464-018-6289-7.
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    • Mantyh, Christopher. “Expert Commentary on Anastomotic Leak After Colonic Resection.” Dis Colon Rectum 62, no. 1 (January 2019): 12–13. https://doi.org/10.1097/DCR.0000000000001268.
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    • Turner, Megan C., Mohamed A. Adam, Christopher R. Mantyh, and John Migaly. “Response: "Recognizing Implicit Bias, Not Proteomics, Is the Next Step in Mitigating Disparities in Surgical Care".” Ann Surg 268, no. 6 (December 2018): e49–50. https://doi.org/10.1097/SLA.0000000000002589.
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    • Turner, Megan C., Julia D. O’Brien, Rachel M. Kahn, Christopher R. Mantyh, John Migaly, and Dan Ariely. “Impact of Disgust on Intentions to Undergo Colorectal Surgery.” Dis Colon Rectum 61, no. 12 (December 2018): 1386–92. https://doi.org/10.1097/DCR.0000000000001254.
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    • Ezekian, Brian, Mohamad A. Adam, Megan C. Turner, Brian F. Gilmore, Kyle Freischlag, Harold J. Leraas, Christopher R. Mantyh, and John Migaly. “Local excision results in comparable survival to radical resection for early-stage rectal carcinoid.” J Surg Res 230 (October 2018): 28–33. https://doi.org/10.1016/j.jss.2018.04.038.
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    • Sun, Zhifei, Megan C. Turner, John Migaly, and Christopher R. Mantyh. “Response to Letter to the Editor.” Dis Colon Rectum 61, no. 5 (May 2018): e36–37. https://doi.org/10.1097/DCR.0000000000001092.
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    • Turner, M. C., Z. Sun, J. Migaly, and C. R. Mantyh. “Response to Mroczkowski.” Colorectal Dis 20, no. 5 (May 2018): 452–53. https://doi.org/10.1111/codi.14109.
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    • Kokosis, G., A. Barbas, C. Ong, H. Levinson, D. Erdmann, and C. R. Mantyh. “Flap repair of complex pilonidal sinus: a single institution experience.” European Journal of Plastic Surgery 41, no. 2 (April 1, 2018): 217–22. https://doi.org/10.1007/s00238-017-1361-4.
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    • Turner, Megan C., Norma E. Farrow, Kristen E. Rhodin, Zhifei Sun, Mohamed A. Adam, Christopher R. Mantyh, and John Migaly. “Delay in Adjuvant Chemotherapy and Survival Advantage in Stage III Colon Cancer.” J Am Coll Surg 226, no. 4 (April 2018): 670–78. https://doi.org/10.1016/j.jamcollsurg.2017.12.048.
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    • Turner, Megan C., Mohamed Abdelgadir Adam, Zhifei Sun, Jina Kim, Brian Ezekian, Babatunde A. Yerokun, Christopher R. Mantyh, and John Migaly. “Response to Letter: Comment on "Insurance Status, Not Race Is Associated With Use of Minimally Invasive Surgical Approach for Rectal Cancer".” Ann Surg 267, no. 2 (February 2018): e30. https://doi.org/10.1097/SLA.0000000000001974.
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    • Adam, Mohamed Abdelgadir, Megan C. Turner, Zhifei Sun, Jina Kim, Brian Ezekian, John Migaly, and Christopher R. Mantyh. “The appropriateness of 30-day mortality as a quality metric in colorectal cancer surgery.” Am J Surg 215, no. 1 (January 2018): 66–70. https://doi.org/10.1016/j.amjsurg.2017.04.018.
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    • Sun, Z., M. A. Adam, J. Kim, M. C. Turner, D. A. Fisher, K. R. Choudhury, B. G. Czito, J. Migaly, and C. R. Mantyh. “Association between neoadjuvant chemoradiation and survival for patients with locally advanced rectal cancer.” Colorectal Dis 19, no. 12 (December 2017): 1058–66. https://doi.org/10.1111/codi.13754.
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    • Sun, Zhifei, Brian Gilmore, Mohamed A. Adam, Jina Kim, Shiao-Wen D. Hsu, John Migaly, and Christopher R. Mantyh. “Adjuvant Chemotherapy After Preoperative Chemoradiation Improves Survival in Patients With Locally Advanced Rectal Cancer.” Dis Colon Rectum 60, no. 10 (October 2017): 1050–56. https://doi.org/10.1097/DCR.0000000000000907.
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    • Casey, A. L., J. M. Badia, A. Higgins, J. Korndorffer, C. Mantyh, O. Mimoz, and M. Moro. “Skin antisepsis: it's not only what you use, it's the way that you use it.” J Hosp Infect 96, no. 3 (July 2017): 221–22. https://doi.org/10.1016/j.jhin.2017.04.019.
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    • Freischlag, Kyle, Zhifei Sun, Mohamed A. Adam, Jina Kim, Manisha Palta, Brian G. Czito, John Migaly, and Christopher R. Mantyh. “Association Between Incomplete Neoadjuvant Radiotherapy and Survival for Patients With Locally Advanced Rectal Cancer.” Jama Surg 152, no. 6 (June 1, 2017): 558–64. https://doi.org/10.1001/jamasurg.2017.0010.
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    • Madden-Fuentes, Ramiro Jose, Bridget F. Koontz, Michael R. Harrison, Daniel J. George, Brittany Davidson, Brian F. Gilmore, Judd W. Moul, Christopher Mantyh, and Andrew C. Peterson. “How Can We Effectively Address the Medical and Psychological Concerns of Survivors of Pelvic Malignancies?” Oncology (Williston Park) 31, no. 4 (April 15, 2017): 286–94.
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    • Bendersky, Victoria, Zhifei Sun, Mohamed A. Adam, Christel Rushing, Jina Kim, Linda Youngwirth, Megan Turner, John Migaly, and Christopher R. Mantyh. “Determining the Optimal Quantitative Threshold for Preoperative Albumin Level Before Elective Colorectal Surgery.” J Gastrointest Surg 21, no. 4 (April 2017): 692–99. https://doi.org/10.1007/s11605-017-3370-9.
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    • Leraas, Harold J., Cecilia T. Ong, Zhifei Sun, Mohamed A. Adam, Jina Kim, Brian F. Gilmore, Brian Ezekian, Uttara S. Nag, Christopher R. Mantyh, and John Migaly. “Hand-Assisted Laparoscopic Colectomy Improves Perioperative Outcomes Without Increasing Operative Time Compared to the Open Approach: a National Analysis of 8791 Patients.” J Gastrointest Surg 21, no. 4 (April 2017): 684–91. https://doi.org/10.1007/s11605-016-3350-5.
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    • Turner, Megan, Mohamed Abdelgadir Adam, Zhifei Sun, Jina Kim, Brian Ezekian, Babatunde Yerokun, Christopher Mantyh, and John Migaly. “Insurance Status, Not Race, is Associated With Use of Minimally Invasive Surgical Approach for Rectal Cancer.” Ann Surg 265, no. 4 (April 2017): 774–81. https://doi.org/10.1097/SLA.0000000000001781.
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    • Mantyh, Christopher R., Hugo Xi, Lena Pearson, and Trish M. Perl. “Minimizing hair dispersal: Is this an opportunity for improvement in health care-acquired infection prevention?” Am J Infect Control 45, no. 3 (March 1, 2017): 308–10. https://doi.org/10.1016/j.ajic.2016.09.001.
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    • Kokosis, George, Zhifei Sun, Yash J. Avashia, Mohamed A. Adam, Howard Levinson, Detlev Erdmann, Christopher R. Mantyh, and John Migaly. “V-Y fasciocutaneous flap closure technique is a safe and efficacious alternative to primary closure of the perineal wound following abdominoperineal resection.” Am J Surg 213, no. 2 (February 2017): 371–76. https://doi.org/10.1016/j.amjsurg.2016.04.018.
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    • Sun, Zhifei, Mohamed A. Adam, Jina Kim, Brian Czito, Christopher Mantyh, and John Migaly. “Intensity-Modulated Radiation Therapy Is Not Associated with Perioperative or Survival Benefit over 3D-Conformal Radiotherapy for Rectal Cancer.” J Gastrointest Surg 21, no. 1 (January 2017): 106–11. https://doi.org/10.1007/s11605-016-3242-8.
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    • Giattino, Charles M., Jacob E. Gardner, Faris M. Sbahi, Kenneth C. Roberts, Mary Cooter, Eugene Moretti, Jeffrey N. Browndyke, et al. “Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults.” Front Syst Neurosci 11 (2017): 24. https://doi.org/10.3389/fnsys.2017.00024.
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    • Gilmore, Brian F., Zhifei Sun, Mohamed Adam, Jina Kim, Brian Ezekian, Cecilia Ong, John Migaly, and Christopher R. Mantyh. “Hand-Assisted Laparoscopic Versus Standard Laparoscopic Colectomy: Are Outcomes and Operative Time Different?” J Gastrointest Surg 20, no. 11 (November 2016): 1854–60. https://doi.org/10.1007/s11605-016-3206-z.
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    • Hirschey, Rachel, Isaac Lipkus, Lee Jones, Christopher Mantyh, Richard Sloane, and Wendy Demark-Wahnefried. “Message Framing and Physical Activity Promotion in Colorectal Cancer Survivors.” Oncol Nurs Forum 43, no. 6 (November 1, 2016): 697–705. https://doi.org/10.1188/16.ONF.43-06AP.
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    • Ezekian, Brian, Zhifei Sun, Mohamed A. Adam, Jina Kim, Megan C. Turner, Brian F. Gilmore, Cecilia T. Ong, Christopher R. Mantyh, and John Migaly. “Robotic-Assisted Versus Laparoscopic Colectomy Results in Increased Operative Time Without Improved Perioperative Outcomes.” J Gastrointest Surg 20, no. 8 (August 2016): 1503–10. https://doi.org/10.1007/s11605-016-3124-0.
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    • Gilmore, B., B. Ezekian, Z. Sun, A. Peterson, and C. Mantyh. “Urinary Dysfunction in the Rectal Cancer Survivor.” Current Bladder Dysfunction Reports 11, no. 2 (June 1, 2016): 105–12. https://doi.org/10.1007/s11884-016-0357-4.
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    • Sun, Zhifei, Jina Kim, Mohamed A. Adam, Daniel P. Nussbaum, Paul J. Speicher, Christopher R. Mantyh, and John Migaly. “Minimally Invasive Versus Open Low Anterior Resection: Equivalent Survival in a National Analysis of 14,033 Patients With Rectal Cancer.” Ann Surg 263, no. 6 (June 2016): 1152–58. https://doi.org/10.1097/SLA.0000000000001388.
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    • Yerokun, Babatunde A., Mohamed A. Adam, Zhifei Sun, Jina Kim, Shanna Sprinkle, John Migaly, and Christopher R. Mantyh. “Does Conversion in Laparoscopic Colectomy Portend an Inferior Oncologic Outcome? Results from 104,400 Patients.” J Gastrointest Surg 20, no. 5 (May 2016): 1042–48. https://doi.org/10.1007/s11605-016-3073-7.
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    • Gulack, Brian C., Daniel P. Nussbaum, Jeffrey E. Keenan, Asvin M. Ganapathi, Zhifei Sun, Mathias Worni, John Migaly, and Christopher R. Mantyh. “Surgical Resection of the Primary Tumor in Stage IV Colorectal Cancer Without Metastasectomy is Associated With Improved Overall Survival Compared With Chemotherapy/Radiation Therapy Alone.” Dis Colon Rectum 59, no. 4 (April 2016): 299–305. https://doi.org/10.1097/DCR.0000000000000546.
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    • Sun, Zhifei, Mohamed A. Adam, Jina Kim, Mithun Shenoi, John Migaly, and Christopher R. Mantyh. “Optimal Timing to Surgery after Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.” J Am Coll Surg 222, no. 4 (April 2016): 367–74. https://doi.org/10.1016/j.jamcollsurg.2015.12.017.
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    • Mantyh, Christopher. “Mechanical bowel preps improve surgical outcomes in colorectal surgery.” Evid Based Med 21, no. 1 (February 2016): 27. https://doi.org/10.1136/ebmed-2015-110323.
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    • Sun, Zhifei, Mohamed A. Adam, Jina Kim, Daniel P. Nussbaum, Ehsan Benrashid, Christopher R. Mantyh, and John Migaly. “Determining the Optimal Timing for Initiation of Adjuvant Chemotherapy After Resection for Stage II and III Colon Cancer.” Dis Colon Rectum 59, no. 2 (February 2016): 87–93. https://doi.org/10.1097/DCR.0000000000000518.
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    • Fleshman, James W Jr, Eugene “‘Chip’” Foley, Jose Guillem, and Christopher Mantyh. “Optimal Timing to Surgery after Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer Discussion.” Journal of the American College of Surgeons 222, no. 4 (2016): 374–76.
    • Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Daniel P. Nussbaum, Christopher R. Mantyh, and John Migaly. “Robotic Low Anterior Resection for Rectal Cancer: A National Perspective on Short-term Oncologic Outcomes.” Ann Surg 262, no. 6 (December 2015): 1040–45. https://doi.org/10.1097/SLA.0000000000001017.
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    • Keenan, Jeffrey E., Paul J. Speicher, Daniel P. Nussbaum, Mohamed Abdelgadir Adam, Timothy E. Miller, Christopher R. Mantyh, and Julie K. M. Thacker. “Improving Outcomes in Colorectal Surgery by Sequential Implementation of Multiple Standardized Care Programs.” J Am Coll Surg 221, no. 2 (August 2015): 404-14.e1. https://doi.org/10.1016/j.jamcollsurg.2015.04.008.
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    • Scarborough, John E., Christopher R. Mantyh, Zhifei Sun, and John Migaly. “Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP.” Ann Surg 262, no. 2 (August 2015): 331–37. https://doi.org/10.1097/SLA.0000000000001041.
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    • Sun, Z., J. Galeotti, S. J. McCall, and C. Mantyh. “Metastatic gallbladder cancer masquerading as primary colon malignancy.” Clinical Medicine Review Case Reports 2 (June 1, 2015): 1–3.
    • Ganapathi, Asvin M., Paul J. Speicher, Brian R. Englum, Anthony W. Castleberry, John Migaly, David S. Hsu, and Christopher R. Mantyh. “Adjuvant chemotherapy for t1 node-positive colon cancers provides significant survival benefit.” Dis Colon Rectum 57, no. 12 (December 2014): 1341–48. https://doi.org/10.1097/DCR.0000000000000245.
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    • Speicher, Paul J., Daniel P. Nussbaum, John E. Scarborough, Sabino Zani, Rebekah R. White, Dan G. Blazer, Christopher R. Mantyh, Douglas S. Tyler, and Bryan M. Clary. “Wound classification reporting in HPB surgery: can a single word change public perception of institutional performance?” Hpb (Oxford) 16, no. 12 (December 2014): 1068–73. https://doi.org/10.1111/hpb.12275.
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    • Kokosis, G., R. Schmitz, A. A. Secord, L. J. Havrilesky, A. Berchuck, C. R. Mantyh, and D. Erdmann. “A modified bipedicle VRAM flap for simultaneous reconstruction of a perineal and posterior vaginal defect.” Gynakologe 47, no. 10 (October 14, 2014): 784–87. https://doi.org/10.1007/s00129-014-3448-3.
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    • Keenan, Jeffrey E., Paul J. Speicher, Julie K. M. Thacker, Monica Walter, Maragatha Kuchibhatla, and Christopher R. Mantyh. “The preventive surgical site infection bundle in colorectal surgery: an effective approach to surgical site infection reduction and health care cost savings.” Jama Surg 149, no. 10 (October 2014): 1045–52. https://doi.org/10.1001/jamasurg.2014.346.
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    • Hanna, Jennifer M., Ryan Turley, Anthony Castleberry, Thomas Hopkins, Andrew C. Peterson, Christopher Mantyh, and John Migaly. “Surgical management of complex rectourethral fistulas in irradiated and nonirradiated patients.” Dis Colon Rectum 57, no. 9 (September 2014): 1105–12. https://doi.org/10.1097/DCR.0000000000000175.
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    • Hanna, Jennifer M., Andrew C. Peterson, and Christopher Mantyh. “Rectourethral fistulas in the cancer survivor.” Curr Opin Urol 24, no. 4 (July 2014): 382–88. https://doi.org/10.1097/MOU.0000000000000073.
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    • Castleberry, A. W., U. Güller, I. Tarantino, M. F. Berry, L. Brügger, R. Warschkow, T. Cerny, C. R. Mantyh, D. Candinas, and M. Worni. “Discrete improvement in racial disparity in survival among patients with stage IV colorectal cancer: a 21-year population-based analysis.” J Gastrointest Surg 18, no. 6 (June 2014): 1194–1204. https://doi.org/10.1007/s11605-014-2515-3.
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    • Miller, Timothy E., Julie K. Thacker, William D. White, Christopher Mantyh, John Migaly, Juying Jin, Anthony M. Roche, et al. “Reduced length of hospital stay in colorectal surgery after implementation of an enhanced recovery protocol.” Anesth Analg 118, no. 5 (May 2014): 1052–61. https://doi.org/10.1213/ANE.0000000000000206.
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    • Speicher, P. J., C. Ligh, J. E. Scarborough, J. K. Thacker, C. R. Mantyh, R. S. Turley, and J. Migaly. “A simple scoring system for risk-stratifying rectal cancer patients prior to radical resection.” Tech Coloproctol 18, no. 5 (May 2014): 459–65. https://doi.org/10.1007/s10151-013-1076-x.
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    • Speicher, Paul J., Brian R. Englum, Betty Jiang, Ricardo Pietrobon, Christopher R. Mantyh, and John Migaly. “The impact of laparoscopic versus open approach on reoperation rate after segmental colectomy: a propensity analysis.” J Gastrointest Surg 18, no. 2 (February 2014): 378–84. https://doi.org/10.1007/s11605-013-2289-z.
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    • Turley, R. S., C. R. Mantyh, and J. Migaly. “Minimally invasive surgery for diverticulitis.” Tech Coloproctol 17 Suppl 1 (February 2013): S11–22. https://doi.org/10.1007/s10151-012-0940-4.
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    • Turley, Ryan S., Andrew S. Barbas, Michael E. Lidsky, Christopher R. Mantyh, John Migaly, and John E. Scarborough. “Laparoscopic versus open Hartmann procedure for the emergency treatment of diverticulitis: a propensity-matched analysis.” Dis Colon Rectum 56, no. 1 (January 2013): 72–82. https://doi.org/10.1097/DCR.0b013e3182749cf5.
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    • Worni, Mathias, Christopher R. Mantyh, Igor Akushevich, Ricardo Pietrobon, and Bryan M. Clary. “Is there a role for simultaneous hepatic and colorectal resections? A contemporary view from NSQIP.” J Gastrointest Surg 16, no. 11 (November 2012): 2074–85. https://doi.org/10.1007/s11605-012-1990-7.
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    • Barbas, Andrew S., Ryan S. Turley, Christopher R. Mantyh, and John Migaly. “Effect of surgeon specialization on long-term survival following colon cancer resection at an NCI-designated cancer center.” J Surg Oncol 106, no. 3 (September 1, 2012): 219–23. https://doi.org/10.1002/jso.22154.
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    • Fuente, Sebastian G. de la, Kirk A. Ludwig, Douglas S. Tyler, and Christopher R. Mantyh. “Ex vivo evaluation of preoperatively treated rectal cancer specimens of patients undergoing radical resection.” Ann Surg Oncol 19, no. 6 (June 2012): 1954–58. https://doi.org/10.1245/s10434-012-2259-9.
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    • Ganapathi, Asvin M., Tammy Westmoreland, Douglas Tyler, and Christopher R. Mantyh. “Bevacizumab-associated fistula formation in postoperative colorectal cancer patients.” J Am Coll Surg 214, no. 4 (April 2012): 582–88. https://doi.org/10.1016/j.jamcollsurg.2011.12.030.
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    • VanDeusen, Jeffrey Bryan, Joshua Uronis, Michael Morse, Michael L. Gatza, Michael B. Datto, Christopher Mantyh, H Kim Lyerly, Joseph R. Nevins, Bryan M. Clary, and Shiaowen David Hsu. “Predictive and prognostic markers of recurrence after resection of primary or metastatic colorectal cancer.” Journal of Clinical Oncology 30, no. 4_suppl (February 1, 2012): 447–447. https://doi.org/10.1200/jco.2012.30.4_suppl.447.
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    • Guillem, Jose, John Pemberton, Patrick O’Leary, David Cole, Harry Papaconstantinou, Mark Duncan, and Christopher Mantyh. “Bevacizumab-Associated Fistula Formation in Postoperative Colorectal Cancer Patients Discussion.” Journal of the American College of Surgeons 214, no. 4 (2012): 588–90.
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    • Uronis, Joshua M., Takuya Osada, Shannon McCall, Xiao Yi Yang, Christopher Mantyh, Michael A. Morse, H Kim Lyerly, Bryan M. Clary, and David S. Hsu. “Histological and molecular evaluation of patient-derived colorectal cancer explants.” Plos One 7, no. 6 (2012): e38422. https://doi.org/10.1371/journal.pone.0038422.
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    • Terry, Neil, Yizheng Zhu, Julie K. M. Thacker, John Migaly, Cynthia Guy, Christopher R. Mantyh, and Adam Wax. “Detection of intestinal dysplasia using angle-resolved low coherence interferometry.” J Biomed Opt 16, no. 10 (October 2011): 106002. https://doi.org/10.1117/1.3631799.
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    • Barbas, Andrew, Ryan Turley, Christopher Mantyh, and John Migaly. “Advanced fellowship training is associated with improved lymph node retrieval in colon cancer resections.” J Surg Res 170, no. 1 (September 2011): e41–46. https://doi.org/10.1016/j.jss.2011.03.055.
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    • Hadeed, Josef G., Mark D. Walsh, Theodore N. Pappas, Ivo A. Pestana, Douglas S. Tyler, Howard Levinson, Christopher Mantyh, Danny O. Jacobs, Sandhya A. Lagoo-Deenadalayan, and Detlev Erdmann. “Complex abdominal wall hernias: a new classification system and approach to management based on review of 133 consecutive patients.” Ann Plast Surg 66, no. 5 (May 2011): 497–503. https://doi.org/10.1097/SAP.0b013e3182145387.
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    • Duda, Dan G., Christopher G. Willett, Marek Ancukiewicz, Emmanuelle di Tomaso, Mira Shah, Brian G. Czito, Rex Bentley, et al. “Abstract LB-213: Plasma soluble VEGFR1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.” Cancer Research 70, no. 8_Supplement (April 15, 2010). https://doi.org/10.1158/1538-7445.am10-lb-213.
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    • Duda, Dan G., Christopher G. Willett, Marek Ancukiewicz, Emmanuelle di Tomaso, Mira Shah, Brian G. Czito, Rex Bentley, et al. “Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.” Oncologist 15, no. 6 (2010): 577–83. https://doi.org/10.1634/theoncologist.2010-0029.
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    • Willett, Christopher G., Dan G. Duda, Marek Ancukiewicz, Mira Shah, Brian G. Czito, Rex Bentley, Martin Poleski, et al. “A safety and survival analysis of neoadjuvant bevacizumab with standard chemoradiation in a phase I/II study compared with standard chemoradiation in locally advanced rectal cancer.” Oncologist 15, no. 8 (2010): 845–51. https://doi.org/10.1634/theoncologist.2010-0030.
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    • Fuente, Sebastian G. de la, Roberto J. Manson, Kirk A. Ludwig, and Christopher R. Mantyh. “Neoadjuvant chemoradiation for rectal cancer reduces lymph node harvest in proctectomy specimens.” J Gastrointest Surg 13, no. 2 (February 2009): 269–74. https://doi.org/10.1007/s11605-008-0717-2.
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    • Takami, Yoji, Christopher R. Mantyh, Theodore N. Pappas, Toku Takahashi, Keiji Koda, and Masaru Miyazaki. “Extrinsic surgical denervation ameliorates TNBS-induced colitis in rats.” Hepatogastroenterology 56, no. 91–92 (2009): 682–86.
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    • Taniguchi, Hiroshi, Hajime Ariga, Jun Zheng, Kirk Ludwig, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Endogenous ghrelin and 5-HT regulate interdigestive gastrointestinal contractions in conscious rats.” Am J Physiol Gastrointest Liver Physiol 295, no. 2 (August 2008): G403–11. https://doi.org/10.1152/ajpgi.90260.2008.
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    • Kalady, Matthew F., Christopher R. Mantyh, Jason Petrofski, and Kirk A. Ludwig. “Routine contrast imaging of low pelvic anastomosis prior to closure of defunctioning ileostomy: is it necessary?” J Gastrointest Surg 12, no. 7 (July 2008): 1227–31. https://doi.org/10.1007/s11605-008-0510-2.
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    • Lee, Woo Yong, Toku Takahashi, Theodore Pappas, Christopher R. Mantyh, and Kirk A. Ludwig. “Surgical autonomic denervation results in altered colonic motility: an explanation for low anterior resection syndrome?” Surgery 143, no. 6 (June 2008): 778–83. https://doi.org/10.1016/j.surg.2008.03.014.
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    • Ariga, Hajime, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Does ghrelin explain accelerated gastric emptying in the early stages of diabetes mellitus?” Am J Physiol Regul Integr Comp Physiol 294, no. 6 (June 2008): R1807–12. https://doi.org/10.1152/ajpregu.00785.2007.
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    • Takahashi, Toku, Yukiomi Nakade, Hiroyuki Fukuda, Kiyoshi Tsukamoto, Christopher Mantyh, and Theodore N. Pappas. “Daily intake of high dietary fiber slows accelerated colonic transit induced by restrain stress in rats.” Dig Dis Sci 53, no. 5 (May 2008): 1271–77. https://doi.org/10.1007/s10620-008-0228-8.
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    • Fuente, S. G. de la, and C. R. Mantyh. “Outcomes Review of Reconstructive Techniques Following Proctectomy.” Seminars in Colon and Rectal Surgery 19, no. 1 (March 1, 2008): 41–47. https://doi.org/10.1053/j.scrs.2008.01.009.
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    • Ariga, Hajime, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Fixed feeding potentiates interdigestive gastric motor activity in rats: importance of eating habits for maintaining interdigestive MMC.” Am J Physiol Gastrointest Liver Physiol 294, no. 3 (March 2008): G655–59. https://doi.org/10.1152/ajpgi.00484.2007.
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    • Imai, Kenji, Hajime Ariga, Cindy Chen, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Effects of electroacupuncture on gastric motility and heart rate variability in conscious rats.” Auton Neurosci 138, no. 1–2 (February 29, 2008): 91–98. https://doi.org/10.1016/j.autneu.2007.11.003.
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    • Ariga, Hajime, Yukiomi Nakade, Kiyoshi Tsukamoto, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Ghrelin accelerates gastric emptying via early manifestation of antro-pyloric coordination in conscious rats.” Regul Pept 146, no. 1–3 (February 7, 2008): 112–16. https://doi.org/10.1016/j.regpep.2007.08.022.
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    • Reddy, Srinevas K., Timothy M. Pawlik, Daria Zorzi, Ana L. Gleisner, Dario Ribero, Lia Assumpcao, Andrew S. Barbas, et al. “Simultaneous resections of colorectal cancer and synchronous liver metastases: a multi-institutional analysis.” Ann Surg Oncol 14, no. 12 (December 2007): 3481–91. https://doi.org/10.1245/s10434-007-9522-5.
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    • Patwardhan, Meenal, Deborah A. Fisher, Christopher R. Mantyh, Douglas C. McCrory, Michael A. Morse, Robert G. Prosnitz, Kathryn Cline, and Gregory P. Samsa. “Assessing the quality of colorectal cancer care: do we have appropriate quality measures? (A systematic review of literature).” J Eval Clin Pract 13, no. 6 (December 2007): 831–45. https://doi.org/10.1111/j.1365-2753.2006.00762.x.
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    • Ueno, Tomio, Sebastian G. de la Fuente, Omar I. Abdel-Wahab, Toku Takahashi, Marcia Gottfried, Mary B. Harris, Makoto Tatewaki, et al. “Functional evaluation of the grafted wall with porcine-derived small intestinal submucosa (SIS) to a stomach defect in rats.” Surgery 142, no. 3 (September 2007): 376–83. https://doi.org/10.1016/j.surg.2007.04.019.
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    • Fuente, Sebastian G. de la, and Christopher R. Mantyh. “Reconstruction techniques after proctectomy: what's the best?” Clin Colon Rectal Surg 20, no. 3 (August 2007): 221–30. https://doi.org/10.1055/s-2007-984866.
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    • Takami, Yoji, Michael B. Russell, Chengjiang Gao, Zhiyong Mi, Hongtao Guo, Christopher R. Mantyh, and Paul C. Kuo. “Sp1 regulates osteopontin expression in SW480 human colon adenocarcinoma cells.” Surgery 142, no. 2 (August 2007): 163–69. https://doi.org/10.1016/j.surg.2007.02.015.
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    • Ariga, H., K. Tsukamoto, C. Chen, C. Mantyh, T. N. Pappas, and T. Takahashi. “Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach.” Neurogastroenterol Motil 19, no. 8 (August 2007): 675–80. https://doi.org/10.1111/j.1365-2982.2007.00945.x.
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    • Tsukamoto, Kiyoshi, Hajime Ariga, Chris Mantyh, Theodore N. Pappas, Hidenori Yanagi, Takehira Yamamura, and Toku Takahashi. “Luminally released serotonin stimulates colonic motility and accelerates colonic transit in rats.” Am J Physiol Regul Integr Comp Physiol 293, no. 1 (July 2007): R64–69. https://doi.org/10.1152/ajpregu.00856.2006.
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    • Czito, Brian G., Johanna C. Bendell, Christopher G. Willett, Michael A. Morse, Gerard C. Blobe, Douglas S. Tyler, John Thomas, et al. “Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: Phase I trial results.” Int J Radiat Oncol Biol Phys 68, no. 2 (June 1, 2007): 472–78. https://doi.org/10.1016/j.ijrobp.2007.02.001.
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    • Nakade, Yukiomi, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Fecal pellet output does not always correlate with colonic transit in response to restraint stress and corticotropin-releasing factor in rats.” J Gastroenterol 42, no. 4 (April 2007): 279–82. https://doi.org/10.1007/s00535-006-1947-2.
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    • Nakade, Yukiomi, Hiroyuki Fukuda, Masahiro Iwa, Kiyoshi Tsukamoto, Hidenori Yanagi, Takehira Yamamura, Christopher Mantyh, Theodore N. Pappas, and Toku Takahashi. “Restraint stress stimulates colonic motility via central corticotropin-releasing factor and peripheral 5-HT3 receptors in conscious rats.” Am J Physiol Gastrointest Liver Physiol 292, no. 4 (April 2007): G1037–44. https://doi.org/10.1152/ajpgi.00419.2006.
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    • Prosnitz, Robert G., Meenal B. Patwardhan, Gregory P. Samsa, Christopher R. Mantyh, Deborah A. Fisher, Douglas C. McCrory, Kathryn E. Cline, Rebecca N. Gray, and Michael A. Morse. “Quality measures for the use of adjuvant chemotherapy and radiation therapy in patients with colorectal cancer: a systematic review.” Cancer 107, no. 10 (November 15, 2006): 2352–60. https://doi.org/10.1002/cncr.22278.
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    • Fukuda, Hiroyuki, Kiyotaka Suenaga, Daisuke Tsuchida, Christopher R. Mantyh, Theodore N. Pappas, Gareth A. Hicks, Diane L. Dehaven-Hudkins, and Toku Takahashi. “The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats.” Brain Res 1102, no. 1 (August 2, 2006): 63–70. https://doi.org/10.1016/j.brainres.2006.02.092.
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    • Patwardhan, M. B., G. P. Samsa, M. A. Michael, R. G. Prosnitz, D. A. Fisher, C. R. Mantyh, and D. C. McCrory. “Quality measures for the diagnosis and management of colorectal cancer.” J Clin Oncol 24, no. 18_suppl (June 20, 2006): 16031.
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    • Tsukamoto, Kiyoshi, Yukiomi Nakade, Christopher Mantyh, Kirk Ludwig, Theodore N. Pappas, and Toku Takahashi. “Peripherally administered CRF stimulates colonic motility via central CRF receptors and vagal pathways in conscious rats.” Am J Physiol Regul Integr Comp Physiol 290, no. 6 (June 2006): R1537–41. https://doi.org/10.1152/ajpregu.00713.2005.
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    • Patwardhan, Meenal B., Gregory P. Samsa, Douglas C. McCrory, Deborah A. Fisher, Christopher R. Mantyh, Michael A. Morse, Robert G. Prosnitz, Kathryn E. Cline, and Rebecca N. Gray. “Cancer care quality measures: diagnosis and treatment of colorectal cancer.” Evid Rep Technol Assess (Full Rep), no. 138 (May 2006): 1–116.
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    • Fukuda, Hiroyuki, Cindy Chen, Christopher Mantyh, Kirk Ludwig, Theodore N. Pappas, and Toku Takahashi. “The herbal medicine, Dai-Kenchu-to, accelerates delayed gastrointestinal transit after the operation in rats.” J Surg Res 131, no. 2 (April 2006): 290–95. https://doi.org/10.1016/j.jss.2005.09.018.
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    • Czito, Brian G., Christopher G. Willett, Johanna C. Bendell, Michael A. Morse, Douglas S. Tyler, Nishan H. Fernando, Christopher R. Mantyh, et al. “Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results.” J Clin Oncol 24, no. 4 (February 1, 2006): 656–62. https://doi.org/10.1200/JCO.2005.04.1749.
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    • Fujino, K., S. G. de la Fuente, Y. Takami, T. Takahashi, and C. R. Mantyh. “Attenuation of acid induced oesophagitis in VR-1 deficient mice.” Gut 55, no. 1 (January 2006): 34–40. https://doi.org/10.1136/gut.2005.066795.
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    • Fuente, Sebastian G. de la, Shukri F. Khuri, Tracy Schifftner, William G. Henderson, Christopher R. Mantyh, and Theodore N. Pappas. “Comparative analysis of vagotomy and drainage versus vagotomy and resection procedures for bleeding peptic ulcer disease: results of 907 patients from the Department of Veterans Affairs National Surgical Quality Improvement Program database.” J Am Coll Surg 202, no. 1 (January 2006): 78–86. https://doi.org/10.1016/j.jamcollsurg.2005.09.001.
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    • Fujino, Kazunori, Yoji Takami, Sebastian G. de la Fuente, Kirk A. Ludwig, and Christopher R. Mantyh. “Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis.” J Gastrointest Surg 8, no. 7 (November 2004): 842–47. https://doi.org/10.1016/j.gassur.2004.07.011.
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    • Uemura, K., M. Tatewaki, M. B. Harris, T. Ueno, C. R. Mantyh, T. N. Pappas, and T. Takahashi. “Magnitude of abdominal incision affects the duration of postoperative ileus in rats.” Surg Endosc 18, no. 4 (April 2004): 606–10. https://doi.org/10.1007/s00464-003-8161-6.
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    • Czito, Brian G., Timothy J. Hong, Darrel P. Cohen, Douglas S. Tyler, Catherine G. Lee, Mitchell S. Anscher, Kirk A. Ludwig, et al. “A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon.” Int J Radiat Oncol Biol Phys 58, no. 3 (March 1, 2004): 779–85. https://doi.org/10.1016/S0360-3016(03)01567-0.
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    • Onaitis, Mark W., and Christopher Mantyh. “Ileal pouch-anal anastomosis for ulcerative colitis and familial adenomatous polyposis: historical development and current status.” Ann Surg 238, no. 6 Suppl (December 2003): S42–48. https://doi.org/10.1097/01.sla.0000098115.90865.16.
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    • Fuente, Sebastian G. de la, L Scott Levin, James D. Reynolds, Carmen Olivares, Theodore N. Pappas, Kirk A. Ludwig, and Christopher R. Mantyh. “Elective stoma construction improves outcomes in medically intractable pressure ulcers.” Dis Colon Rectum 46, no. 11 (November 2003): 1525–30. https://doi.org/10.1007/s10350-004-6808-6.
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    • Fukumoto, S., M. Tatewaki, T. Yamada, M. Fujimiya, C. Mantyh, M. Voss, S. Eubanks, M. Harris, T. N. Pappas, and T. Takahashi. “Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats.” American Journal of Physiology  Regulatory Integrative and Comparative Physiology 284, no. 5 53-5 (May 1, 2003).
    • Kihara, N., S. G. de la Fuente, K. Fujino, T. Takahashi, T. N. Pappas, and C. R. Mantyh. “Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats.” Gut 52, no. 5 (May 2003): 713–19. https://doi.org/10.1136/gut.52.5.713.
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    • Kalady, Matthew F., Ryan C. Fields, Stephen Klein, Karen C. Nielsen, Christopher R. Mantyh, and Kirk A. Ludwig. “Loop ileostomy closure at an ambulatory surgery facility: a safe and cost-effective alternative to routine hospitalization.” Dis Colon Rectum 46, no. 4 (April 2003): 486–90. https://doi.org/10.1007/s10350-004-6587-0.
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    • Fuente, Sebastian G. de la, Kirk A. Ludwig, and Christopher R. Mantyh. “Preoperative immune status determines anal condyloma recurrence after surgical excision.” Dis Colon Rectum 46, no. 3 (March 2003): 367–73. https://doi.org/10.1007/s10350-004-6557-6.
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    • Fuente, Sebastian G. de la, Marcia R. Gottfried, D Curtis Lawson, Mary B. Harris, Christopher R. Mantyh, and Theodore N. Pappas. “Evaluation of porcine-derived small intestine submucosa as a biodegradable graft for gastrointestinal healing.” J Gastrointest Surg 7, no. 1 (January 2003): 96–101. https://doi.org/10.1016/S1091-255X(02)00050-1.
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    • Onaitis, M. W., R. B. Noone, R. Fields, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival.” Ann Surg Oncol 8, no. 10 (December 2001): 801–6. https://doi.org/10.1007/s10434-001-0801-2.
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    • Onaitis, M. W., R. B. Noone, M. Hartwig, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Neoadjuvant chemoradiation for rectal cancer: analysis of clinical outcomes from a 13-year institutional experience.” Ann Surg 233, no. 6 (June 2001): 778–85. https://doi.org/10.1097/00000658-200106000-00007.
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    • Mantyh, C. R., D. C. McVey, and S. R. Vigna. “Extrinsic surgical denervation inhibits Clostridium difficile toxin A-induced enteritis in rats.” Neurosci Lett 292, no. 2 (October 6, 2000): 95–98. https://doi.org/10.1016/s0304-3940(00)01451-8.
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    • Fazio, V. W., C. R. Mantyh, and T. L. Hull. “Colonic "coloplasty": novel technique to enhance low colorectal or coloanal anastomosis.” Dis Colon Rectum 43, no. 10 (October 2000): 1448–50. https://doi.org/10.1007/BF02236645.
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    • Mantyh, C. R., T. N. Pappas, J. A. Lapp, M. K. Washington, L. M. Neville, J. R. Ghilardi, S. D. Rogers, P. W. Mantyh, and S. R. Vigna. “Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum.” Gastroenterology 111, no. 5 (November 1996): 1272–80. https://doi.org/10.1053/gast.1996.v111.pm8898641.
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    • Mantyh, P. W., S. D. Rogers, J. R. Ghilardi, J. E. Maggio, C. R. Mantyh, and S. R. Vigna. “Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo.” Brain Res 719, no. 1–2 (May 6, 1996): 8–13. https://doi.org/10.1016/0006-8993(96)00050-9.
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    • Mantyh, C. R., J. E. Maggio, P. W. Mantyh, S. R. Vigna, and T. N. Pappas. “Increased substance P receptor expression by blood vessels and lymphoid aggregates in Clostridium difficile-induced pseudomembranous colitis.” Dig Dis Sci 41, no. 3 (March 1996): 614–20. https://doi.org/10.1007/BF02282350.
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    • Mantyh, C. R., S. R. Vigna, R. R. Bollinger, P. W. Mantyh, J. E. Maggio, and T. N. Pappas. “Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis.” Gastroenterology 109, no. 3 (September 1995): 850–60. https://doi.org/10.1016/0016-5085(95)90394-1.
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    • Mantyh, P. W., E. DeMaster, A. Malhotra, J. R. Ghilardi, S. D. Rogers, C. R. Mantyh, H. Liu, A. I. Basbaum, S. R. Vigna, and J. E. Maggio. “Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation.” Science 268, no. 5217 (June 16, 1995): 1629–32. https://doi.org/10.1126/science.7539937.
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    • Mantyh, P. W., C. J. Allen, J. R. Ghilardi, S. D. Rogers, C. R. Mantyh, H. Liu, A. I. Basbaum, S. R. Vigna, and J. E. Maggio. “Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.” Proc Natl Acad Sci U S A 92, no. 7 (March 28, 1995): 2622–26. https://doi.org/10.1073/pnas.92.7.2622.
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    • Mantyh, C. R., T. N. Pappas, and S. R. Vigna. “Localization of cholecystokinin A and cholecystokinin B/gastrin receptors in the canine upper gastrointestinal tract.” Gastroenterology 107, no. 4 (October 1994): 1019–30. https://doi.org/10.1016/0016-5085(94)90226-7.
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    • Mantyh, C. R., S. R. Vigna, J. E. Maggio, P. W. Mantyh, R. R. Bollinger, and T. N. Pappas. “Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors.” Neurosci Lett 178, no. 2 (September 12, 1994): 255–59. https://doi.org/10.1016/0304-3940(94)90772-2.
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    • Lawson, D. C., C. R. Mantyh, and T. N. Pappas. “Effect of CGRP antagonist, alpha-CGRP 8-37, on acid secretion in the dog.” Dig Dis Sci 39, no. 7 (July 1994): 1405–8. https://doi.org/10.1007/BF02088041.
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    • Bacay, A. C., C. R. Mantyh, A. H. Cohen, P. W. Mantyh, and L. G. Fine. “Glomerular atrial natriuretic factor receptors in primary glomerulopathies: studies on human renal biopsies.” Am J Kidney Dis 14, no. 5 (November 1989): 386–95. https://doi.org/10.1016/s0272-6386(89)80172-6.
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    • Vigna, S. R., C. R. Mantyh, A. H. Soll, J. E. Maggio, and P. W. Mantyh. “Substance P receptors on canine chief cells: localization, characterization, and function.” J Neurosci 9, no. 8 (August 1989): 2878–86. https://doi.org/10.1523/JNEUROSCI.09-08-02878.1989.
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    • Gates, T. S., R. P. Zimmerman, C. R. Mantyh, S. R. Vigna, and P. W. Mantyh. “Calcitonin gene-related peptide-alpha receptor binding sites in the gastrointestinal tract.” Neuroscience 31, no. 3 (1989): 757–70. https://doi.org/10.1016/0306-4522(89)90439-9.
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    • Zimmerman, R. P., T. S. Gates, C. R. Mantyh, S. R. Vigna, M. L. Welton, E. P. Passaro, and P. W. Mantyh. “Vasoactive intestinal polypeptide receptor binding sites in the human gastrointestinal tract: localization by autoradiography.” Neuroscience 31, no. 3 (1989): 771–83. https://doi.org/10.1016/0306-4522(89)90440-5.
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    • Mantyh, P. W., M. D. Catton, C. G. Boehmer, M. L. Welton, E. P. Passaro, J. E. Maggio, and S. R. Vigna. “Receptors for sensory neuropeptides in human inflammatory diseases: implications for the effector role of sensory neurons.” Peptides 10, no. 3 (1989): 627–45. https://doi.org/10.1016/0196-9781(89)90154-x.
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    • Mantyh, P. W., T. Gates, C. R. Mantyh, and J. E. Maggio. “Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues.” J Neurosci 9, no. 1 (January 1989): 258–79. https://doi.org/10.1523/JNEUROSCI.09-01-00258.1989.
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    • Kruger, L., P. W. Mantyh, C. Sternini, N. C. Brecha, and C. R. Mantyh. “Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites.” Brain Res 463, no. 2 (November 1, 1988): 223–44. https://doi.org/10.1016/0006-8993(88)90395-2.
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    • Mantyh, P. W., C. R. Mantyh, T. Gates, S. R. Vigna, and J. E. Maggio. “Receptor binding sites for substance P and substance K in the canine gastrointestinal tract and their possible role in inflammatory bowel disease.” Neuroscience 25, no. 3 (June 1988): 817–37. https://doi.org/10.1016/0306-4522(88)90038-3.
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    • Mantyh, C. R., T. S. Gates, R. P. Zimmerman, M. L. Welton, E. P. Passaro, S. R. Vigna, J. E. Maggio, L. Kruger, and P. W. Mantyh. “Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.” Proc Natl Acad Sci U S A 85, no. 9 (May 1988): 3235–39. https://doi.org/10.1073/pnas.85.9.3235.
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    • WELTON, M. L., C. R. MANTYH, T. S. GATES, P. POPPER, S. R. VIGNA, J. E. MAGGIO, E. PASSARO, and P. W. MANTYH. “Localization of Bombesin Receptors in the Human Gastrointestinal Tract Using Quantitative Receptor Autoradiography.” Annals of the New York Academy of Sciences 547, no. 1 (January 1, 1988): 468–70. https://doi.org/10.1111/j.1749-6632.1988.tb23922.x.
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    • Bacay, A. C., C. R. Mantyh, S. R. Vigna, and P. W. Mantyh. “Receptor binding sites for atrial natriuretic factor are expressed by brown adipose tissue.” Peptides 9, no. 5 (1988): 1021–26. https://doi.org/10.1016/0196-9781(88)90083-6.
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    • Gates, T. S., R. P. Zimmerman, C. R. Mantyh, S. R. Vigna, J. E. Maggio, M. L. Welton, E. P. Passaro, and P. W. Mantyh. “Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography.” Peptides 9, no. 6 (1988): 1207–19. https://doi.org/10.1016/0196-9781(88)90184-2.
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    • Popper, P., C. R. Mantyh, S. R. Vigna, J. E. Maggio, and P. W. Mantyh. “The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes.” Peptides 9, no. 2 (1988): 257–67. https://doi.org/10.1016/0196-9781(88)90258-6.
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    • Zimmerman, R. P., T. S. Gates, C. R. Mantyh, S. R. Vigna, C. G. Boehmer, and P. W. Mantyh. “Vasoactive intestinal peptide (VIP) receptors in the canine gastrointestinal tract.” Peptides 9, no. 6 (1988): 1241–53. https://doi.org/10.1016/0196-9781(88)90188-x.
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    • Vigna, S. R., C. R. Mantyh, A. S. Giraud, A. H. Soll, J. H. Walsh, and P. W. Mantyh. “Localization of specific binding sites for bombesin in the canine gastrointestinal tract.” Gastroenterology 93, no. 6 (December 1987): 1287–95. https://doi.org/10.1016/0016-5085(87)90257-5.
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    • Mantyh, C. R., L. Kruger, N. C. Brecha, and P. W. Mantyh. “Localization of specific binding sites for atrial natriuretic factor in the central nervous system of rat, guinea pig, cat and human.” Brain Res 412, no. 2 (June 2, 1987): 329–42. https://doi.org/10.1016/0006-8993(87)91140-1.
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    • Akesson, T. R., P. W. Mantyh, C. R. Mantyh, D. W. Matt, and P. E. Micevych. “Estrous cyclicity of 125I-cholecystokinin octapeptide binding in the ventromedial hypothalamic nucleus. Evidence for downmodulation by estrogen.” Neuroendocrinology 45, no. 4 (April 1987): 257–62. https://doi.org/10.1159/000124737.
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    • Mantyh, C. R., L. Kruger, N. C. Brecha, and P. W. Mantyh. “Localization of specific binding sites for atrial natriuretic factor in peripheral tissues of the guinea pig, rat, and human.” Hypertension 8, no. 8 (August 1986): 712–21. https://doi.org/10.1161/01.hyp.8.8.712.
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    • Mantyh, Christopher, John Migaly, K. Freischlag, and M. Turner. “ASSOCIATION BETWEEN EXTENT OF SURGICAL RESECTION AND OVERALL SURVIVAL IN PATIENTS WITH MUCINOUS NEOPLASMS OF THE APPENDIX.” Diseases of the Colon and Rectum 63, no. 6 (n.d.): E422–23.
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  • Book Sections

    • Moore, H. G., and C. R. Mantyh. “Technique of ileostomy construction and closure.” In Fischer’s Mastery of Surgery, Seventh Edition, 2:1638–49, 2018.
    • Sun, Z., M. A. Adam, and C. R. Mantyh. “Colonic arteriovenous malformations.” In Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management, Second Edition, 159–67, 2016. https://doi.org/10.1007/978-3-319-40646-6_14.
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    • De La Fuente, S. G., and C. R. Mantyh. “Colonic arteriovenous malformations.” In Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management, 155–61, 2010. https://doi.org/10.1007/978-1-4419-1693-8_14.
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    • Olcese, V. A., and C. R. Mantyh. “Bleeding colonic tumors.” In Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management, 163–71, 2010. https://doi.org/10.1007/978-1-4419-1693-8_15.
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  • Other Articles

    • Ludwig, K. A., and C. R. Mantyh. “Invited commentary [1].” Diseases of the Colon and Rectum, August 1, 2007. https://doi.org/10.1007/s10350-007-0250-5.
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    • Ludwig, Kirk A., and Christopher R. Mantyh. “The status of radical proctectomy and sphincter-sparing surgery in the United States - Invited commentary.” Diseases of the Colon & Rectum. SPRINGER, August 1, 2007.
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    • Mantyh, C. R. “Incidence and patterns of recurrence after resection for cure of colonic cancer in a well-defined population: Commentary.” Diseases of the Colon and Rectum, January 1, 2007. https://doi.org/10.1007/s10350-005-0243-1.
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    • Mantyh, C. R. “Population-based study of prognostic factors in stage II colonic cancer: Commentary.” Diseases of the Colon and Rectum, October 1, 2006. https://doi.org/10.1007/s10350-006-0241-y.
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    • Mantyh, C. R. “Long-term results in patients with T2-3 N0 distal rectal cancer undergoing radiotherapy before transanal endoscopic microsurgery: Editorial comment.” Diseases of the Colon and Rectum, May 1, 2006. https://doi.org/10.1007/s10350-005-0237-z.
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    • Mantyh, C. “Salvage reoperation for complications after ileal pouch-anal anastomosis: Commentary.” Diseases of the Colon and Rectum, March 1, 2006. https://doi.org/10.1007/s10350-005-0231-5.
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    • Fox-Threlkeld, J. A., and E. E. Daniel. “How selective are the cholecystokinin antagonists in the dog?” Gastroenterology, June 1995. https://doi.org/10.1016/0016-5085(95)90170-1.
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    • Mantyh, C., T. Pappas, and S. Vigna. “Reply.” Gastroenterology, 1995.
    • Mantyh, C. R., and P. W. Mantyh. “Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain.” Eur J Pharmacol, July 11, 1985. https://doi.org/10.1016/0014-2999(85)90356-5.
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    • Mantyh, C. R., N. C. Brecha, P. Soon-Shiong, and P. W. Mantyh. “Specific binding sites for atrial natriuretic factor in the human kidney.” N Engl J Med, June 27, 1985. https://doi.org/10.1056/NEJM198506273122617.
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  • Conference Papers

    • Hayden, Joshua P., William R. Boysen, Urszula Kowalik, Brian M. Inouye, John Migaly, Christopher R. Mantyh, Detlev Erdmann, and Andrew C. Peterson. “Outcomes of an Algorithmic, Multidisciplinary Approach to Rectourethral Fistula Repair: A Pre- and Postintervention Quasi-Experimental Study.” In Dis Colon Rectum, 66:598–608, 2023. https://doi.org/10.1097/DCR.0000000000002467.
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    • Corrigan, K. L., C. D. Jacobs, H. Williamson, S. Behrens, S. D. Hsu, C. G. Willett, C. R. Mantyh, G. Suneja, and B. Czito. “Differences in Clinicopathologic Features and Response to Neoadjuvant Radiotherapy for Early- Versus Late-Onset Stage II-III Rectal Adenocarcinoma.” In International Journal of Radiation Oncology Biology Physics, 108:E623–E623, 2020.
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    • Freischlag, K., M. Turner, J. Migaly, and C. Mantyh. “ASSOCIATION BETWEEN EXTENT OF SURGICAL RESECTION AND OVERALL SURVIVAL IN PATIENTS WITH MUCINOUS NEOPLASMS OF THE APPENDIX.” In Diseases of the Colon & Rectum, 63:E422–23, 2020.
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    • Olivere, Lindsey A., Kyle W. Freischlag, Megan Turner, John Migaly, and Christopher R. Mantyh. “Association between Survival and Fragmented Care in Stage II and III Rectal Cancer.” In Journal of the American College of Surgeons, 229:S52–S52. ELSEVIER SCIENCE INC, 2019.
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    • Turner, Megan C., Jeffrey E. Keenan, Christel N. Rushing, Brian C. Gulack, Daniel P. Nussbaum, Ehsan Benrashid, Terry Hyslop, John H. Strickler, Christopher R. Mantyh, and John Migaly. “Adjuvant Chemotherapy Improves Survival Following Resection of Locally Advanced Rectal Cancer with Pathologic Complete Response.” In J Gastrointest Surg, 23:1614–22, 2019. https://doi.org/10.1007/s11605-018-04079-8.
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    • Kowalik, Urszula, Brian Inouye, Stephanie Sexton, Brian Gilmore, Andrew Peterson, John Migaly, and Christopher Mantyh. “OUTCOMES OF RECTO-URETHRAL FISTULA REPAIR USING A YORK-MASON PROCEDURE - RETURN TO CONTINUITY OF URINARY AND BOWEL FUNCTION.” In Journal of Urology, 201:E973–E973. LIPPINCOTT WILLIAMS & WILKINS, 2019.
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    • Kowalik, Urszula, Brian Inouye, Stephanie Sexton, Brian Gilmore, Arman Kahokehr, Andrew Peterson, Christopher Mantyh, and John Migaly. “SHORT-TERM SUCCESS DOES NOT GUARANTEE LONG-TERM OUTCOMES IN THE RADIATED RECTO-URETHRAL FISTULA REPAIR PATIENT.” In Journal of Urology, 201:E391–E391. LIPPINCOTT WILLIAMS & WILKINS, 2019.
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    • Cox, Morgan L., Mohamed A. Adam, Mithun M. Shenoi, Megan C. Turner, Zhifei Sun, Christopher R. Mantyh, and John Migaly. “Resected irradiated rectal cancers: Are twelve lymph nodes really necessary in the era of neoadjuvant therapy?” In Am J Surg, 216:444–49, 2018. https://doi.org/10.1016/j.amjsurg.2017.08.014.
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    • Adam, M. A., M. Turner, H. G. Moore, C. R. Mantyh, and J. Migaly. “USE OF NEOADJUVANT SHORT-COURSE RADIOTHERAPY FOR RECTAL ADENOCARCINOMA IN THE UNITED STATES: INSIGHTS INTO PATTERNS OF PRACTICE AND OUTCOMES.” In Diseases of the Colon & Rectum, 61:E71–72. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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    • Turner, M., R. M. Kahn, D. Ariely, C. R. Mantyh, J. Migaly, and J. O’Brien. “THE IMPACT OF DISGUST ON PATIENT INTENT TO UNDERGO COLORECTAL SURGERY AND RECALL OF PERIOPERATIVE INSTRUCTIONS.” In Diseases of the Colon & Rectum, 61:E57–E57. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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    • Leraas, H., M. Turner, R. Kamyszek, Z. Sun, U. Nag, B. Gilmore, J. Migaly, and C. Mantyh. “LONGER OPERATIVE TIME IS ASSOCIATED WITH GREATER RISK OF COMPLICATIONS FOR PATIENTS UNDERGOING ABDOMINOPERINEAL RESECTION.” In Diseases of the Colon & Rectum, 60:E455–E455. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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    • Turner, M., Z. Sun, B. Gilmore, D. Chang, C. Mantyh, J. Migaly, and H. Moore. “PERINEAL AND ABDOMINAL APPROACH FOR RECTAL PROLAPSE: EQUIVALENT DURABILITY AT ONE YEAR.” In Diseases of the Colon & Rectum, 60:E88–E88. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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    • Adam, Mohamed Abdelgadir, Lacey M. Lee, Jina Kim, Mithun Shenoi, Mohan Mallipeddi, Hamza Aziz, Sandra Stinnett, Zhifei Sun, Christopher R. Mantyh, and Julie K. M. Thacker. “Alvimopan Provides Additional Improvement in Outcomes and Cost Savings in Enhanced Recovery Colorectal Surgery.” In Ann Surg, 264:141–46, 2016. https://doi.org/10.1097/SLA.0000000000001428.
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    • Sun, Z., M. Adam, J. Kim, M. Shenoi, S. Hsu, J. Migaly, and C. Mantyh. “ADJUVANT CHEMOTHERAPY AFTER PREOPERATIVE CHEMORADIATION IMPROVES SURVIVAL IN PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER.” In Diseases of the Colon & Rectum, 59:E53–54. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Adam, Mohamed A., Zhifei Sun, Jina Kim, John Migaly, and Christopher R. Mantyh. “1021 Thirty-Day Mortality Underestimates Incidence of Death After Colorectal Surgery for Cancer.” In Gastroenterology, 150:S1199–S1199. Elsevier BV, 2016. https://doi.org/10.1016/s0016-5085(16)34054-9.
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    • Sun, Zhifei, Mohamed A. Adam, Mithun Shenoi, Brian Czito, John Migaly, and Christopher R. Mantyh. “349 Intensity-Modulated Radiation Therapy Is Not Associated With Either Short-Term or Long-Term Benefit Over 3D-Conformal Radiotherapy for Rectal Cancer.” In Gastroenterology, 150:S1175–76. Elsevier BV, 2016. https://doi.org/10.1016/s0016-5085(16)33971-3.
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    • Youngwirth, L., M. Adam, Z. Sun, E. Benrashid, C. Mantyh, J. Migaly, and R. Scheri. “Local Excision has Comparable Survival to Abdominoperineal Resection in Patients with Anal Melanoma: An Analysis of 760 Patients from the National Cancer Data Base.” In Annals of Surgical Oncology, 23:S31–S31. SPRINGER, 2016.
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    • Sun, Zhifei, Mohamed A. Adam, Jina Kim, Shiao-Wen D. Hsu, Manisha Palta, Brian G. Czito, John Migaly, and Christopher Mantyh. “Effect of combined neoadjuvant chemoradiation on overall survival for patients with locally advanced rectal cancer.” In Journal of Clinical Oncology, 34:657–657. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.4_suppl.657.
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    • Adam, M Abdelgadir, Z. Sun, J. Migaly, C. Mantyh, and J. Thacker. “PREDICTORS OF LENGTH OF STAY AND COST IN ENHANCED RECOVERY COLORECTAL SURGERY PROTOCOL.” In Diseases of the Colon & Rectum, 58:E173–74. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Gulack, B., D. Nussbaum, J. Keenan, A. Ganapathi, Z. Sun, M. Worni, J. Migaly, and C. Mantyh. “SURGICAL RESECTION OF THE PRIMARY TUMOR IN STAGE IV COLORECTAL CANCER WITHOUT METASTASECTOMY IS ASSOCIATED WITH IMPROVED OVERALL SURVIVAL COMPARED TO CHEMOTHERAPY/RADIATION THERAPY ALONE.” In Diseases of the Colon & Rectum, 58:E104–5. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Sun, Z., M Abdelgadir Adam, J. Kim, D. Nussbaum, E. Benrashid, C. Mantyh, and J. Migaly. “DETERMINING THE OPTIMAL TIMING FOR INITIATION OF ADJUVANT CHEMOTHERAPY AFTER RESECTION FOR STAGE II/III COLON CANCER.” In Diseases of the Colon & Rectum, 58:E103–E103. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Adam, M Abdelgadir, P. Speicher, L. Lee, J. Migaly, C. Mantyh, and J. Thacker. “IMPACT OF ALVIMOPAN IN COMBINATION WITH EPIDURAL AS PART OF ENHANCED RECOVERY PROGRAM IN COLORECTAL SURGERY.” In Diseases of the Colon & Rectum, 57:E245–46. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Englum, Brian R., Paul J. Speicher, Asvin M. Ganapathi, Anthony Castleberry, Julie K. Thacker, Christopher R. Mantyh, and John Migaly. “Optimizing the Utilization of Adjuvant Chemotherapy Following Surgical Resection of Colon Cancer: A Comparison of Laparoscopic Versus Open Approach.” In Gastroenterology, 146:S549–S549. W B SAUNDERS CO-ELSEVIER INC, 2014.
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    • Ganapathi, A., P. Speicher, B. Englum, A. Castleberry, D. Hsu, and C. Mantyh. “TREATMENT OF T1 NODE POSITIVE COLON CANCER: AN ANALYSIS OF NATIONAL TREATMENT PATTERNS.” In Diseases of the Colon & Rectum, 57:E94–95. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Ganapathi, Asvin M., Brian R. Englum, Paul J. Speicher, Anthony Castleberry, Julie K. Thacker, Christopher R. Mantyh, and John Migaly. “The Effect of Surgical Approach on the Use of Adjuvant Chemotherapy Following Low Anterior Resection for Rectal Cancer.” In Gastroenterology, 146:S1080–81. W B SAUNDERS CO-ELSEVIER INC, 2014.
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    • Keenan, J., P. Speicher, J. Migaly, C. Mantyh, and J. Thacker. “THE ENHANCED RECOVERY PROGRAM AND SURGICAL SITE INFECTION BUNDLE MARKEDLY IMPROVES OUTCOMES IN COLORECTAL SURGERY.” In Diseases of the Colon & Rectum, 57:E183–84. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Mallipeddi, Mohan K., Paul J. Speicher, Asvin M. Ganapathi, Brian R. Englum, John Migaly, and Christopher R. Mantyh. “Effects of Neoadjuvant and Adjuvant Therapy for Rectal Cancer on Long Term Survival.” In Gastroenterology, 146:S342–S342. W B SAUNDERS CO-ELSEVIER INC, 2014.
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    • Nussbaum, Daniel P., Paul J. Speicher, Asvin M. Ganapathi, Brian R. Englum, Jeffrey E. Keenan, Christopher R. Mantyh, and John Migaly. “Short-Term Oncologic Outcomes Are Superior Following Laparoscopic Versus Open Low Anterior Resection for Rectal Cancer: Results From the National Cancer Database.” In Gastroenterology, 146:S1033–S1033. W B SAUNDERS CO-ELSEVIER INC, 2014.
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    • Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Christopher R. Mantyh, and John Migaly. “Robotic Low Anterior Resection for Rectal Cancer and Short-Term Oncologic Outcomes.” In Gastroenterology, 146:S1019–S1019. W B SAUNDERS CO-ELSEVIER INC, 2014.
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    • Gupta, Shubham, Jennifer Hanna, Aaron Lentz, Ngoc-Bich Le, Matthew Fraser, George Webster, Christopher Mantyh, John Migaly, and Andrew Peterson. “PD3-06 OPTIMIZING THE MANAGEMENT OF SURGICAL AND ABLATIVE-ENERGY RECTO-URETHRAL FISTULAS IN THE PROSTATE CANCER SURVIVOR.” In Journal of Urology, Vol. 191. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1016/j.juro.2014.02.151.
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    • Erhunmwunsee, Loretta, Jennifer M. Hanna, Anthony Castleberry, Matthew Hartwig, and Christopher R. Mantyh. “Outcomes of Lung Transplant Patients With Severe GI Complications.” In Gastroenterology, 144:S1089–S1089. W B SAUNDERS CO-ELSEVIER INC, 2013.
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    • Hanna, J., A. Castleberry, J. Thacker, C. Mantyh, and J. Migaly. “PROGNOSTIC IMPORTANCE OF NUMBER OF DISSECTED LYMPH NODES AFTER INDUCTION CHEMORADIATION FOR RECTAL CANCER.” In Diseases of the Colon & Rectum, 56:E229–E229. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Turley, R., C. Ligh, J. Scarborough, J. Thacker, C. Mantyh, and J. Migaly. “A NOVEL SCORING SYSTEM FOR RISK-STRATIFYING RECTAL CANCER PATIENTS PRIOR TO RADICAL RESECTION.” In Diseases of the Colon & Rectum, 56:E94–E94. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Guller, Ulrich, Ignazio Tarantino, Anthony W. Castleberry, Lukas Brugger, Dieter Koeberle, Thomas Cerny, Ricardo Pietrobon, Christopher Mantyh, and Mathias Worni. “Survival trends of 89,543 patients with metastatic colorectal cancer: A population-based analysis.” In Journal of Clinical Oncology, 31:476–476. American Society of Clinical Oncology (ASCO), 2013. https://doi.org/10.1200/jco.2013.31.4_suppl.476.
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    • Uronis, Joshua M., Jeffrey Bryan VanDeusen, Michael B. Datto, Joseph Lucas, Michael Morse, Christopher Mantyh, H Kim Lyerly, Bryan M. Clary, and Shiaowen David Hsu. “A molecular profile of colorectal cancer to guide prognosis and therapy after resection of primary or metastatic disease.” In Journal of Clinical Oncology, 31:339–339. American Society of Clinical Oncology (ASCO), 2013. https://doi.org/10.1200/jco.2013.31.4_suppl.339.
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    • Worni, Mathias, Christopher R. Mantyh, Igor Akushevich, Ricardo Pietrobon, and Bryan M. Clary. “Is There a Role for Simultaneous Hepatic and Colorectal Resections? a Contemporary View From NSQIP.” In Gastroenterology, 142:S1042–S1042. W B SAUNDERS CO-ELSEVIER INC, 2012.
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    • De Rosa, N., J. Scarborough, and C. R. Mantyh. “Laparoscopic vs. Open Resection for Rectal Cancer: A Comparison of Short-term Outcomes.” In Annals of Surgical Oncology, 19:S107–8. SPRINGER, 2012.
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    • Worni, M., C. Mantyh, I. Akushevich, R. Pietrobon, and B. M. Clary. “Is there a role for simultaneous hepatic and colorectal resections? A contemporary view from the national surgical quality improvement program (NSQIP).” In British Journal of Surgery, 99:8–8, 2012.
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    • Fuente, S. de la, K. Ludwig, D. Tyler, and C. Mantyh. “EX-VIVO EVALUATION OF PREOPERATIVELY TREATED RECTAL CANCER SPECIMENS UNDERGOING RADICAL RESECTION.” In Diseases of the Colon & Rectum, 54:E147–48, 2011.
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    • Terry, Neil G., Yizheng Zhu, Cynthia D. Guy, John Migaly, Julie K. Thacker, Christopher R. Mantyh, and Adam Wax. “Detection of Intestinal Dysplasia Using Angle-Resolved Low Coherence Interferometry.” In Gastroenterology, 138:S666–S666. W B SAUNDERS CO-ELSEVIER INC, 2010.
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    • Willett, Christopher G., Dan G. Duda, Marek Ancukiewicz, Mira Shah, Brian Czito, Rex Bentley, Martin Poleski, et al. “Abstract LB-76: A study of neoadjuvant bevacizumab with standard chemoradiation versus chemoradiation alone in locally advanced rectal cancer.” In Cancer Research, Vol. 70. American Association for Cancer Research (AACR), 2010. https://doi.org/10.1158/1538-7445.am10-lb-76.
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    • Haney, J., B. Czito, D. Tyler, C. Mantyh, and J. Migaly. “INTRAOPERATIVE RADIATION THERAPY FOR ADVANCED COLORECTAL CANCER PROVIDES EFFECTIVE LOCAL CONTROL WITH ACCEPTABLE MORBIDITY.” In Diseases of the Colon & Rectum, 53:523–24. LIPPINCOTT WILLIAMS & WILKINS, 2010.
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    • Mantyh, C., N. Terry, Y. Zhu, A. Wax, C. Guy, J. Migaly, and J. Thacker. “DETECTION OF INTESTINAL DYSPLASIA USING ANGLE-RESOLVED LOW COHERENCE INTERFEROMETRY.” In Diseases of the Colon & Rectum, 53:531–33. LIPPINCOTT WILLIAMS & WILKINS, 2010.
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    • Westmoreland, T., D. Tyler, and C. Mantyh. “BEVACIZUMAB ASSOCIATED FISTULA FORMATION IN POSTOPERATIVE PATIENTS WITH ADVANCED COLORECTAL CANCER.” In Diseases of the Colon & Rectum, 53:614–614, 2010.
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    • Shah, M. M., B. Czito, D. G. Duda, C. Mantyh, J. W. Yea, R. K. Jain, and C. G. Willett. “Neoadjuvant Bevacizumab Does Not Appear to Contribute to Postoperative Complications after Surgery of Rectal Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 75:S264–S264. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.608.
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    • Ariga, Hajime, Kenji Imai, Cindy Chen, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Eating behavior modulates ghrelin surge, resulting in potent interdigestive gastric contractions and acceleration of gastric emptying in rats.” In Gastroenterology, 134:A284–A284. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Ariga, Hajime, Kenji Imai, Kirk A. Ludwig, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Time course of gastric emptying, plasma ghrelin levels and autonomic nerves function in the chronic stage of diabetes in rats.” In Gastroenterology, 134:A395–A395. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Ariga, Hajime, Kiyoshi Tsukamoto, Hiroshi Taniguchi, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Plasma insulin, but not glucose, inhibits ghrelin release in vascularly isolated perfused rat stomach ex-vivo; a possible mechanism of increased plasma ghrelin levels in diabetes.” In Gastroenterology, 134:A533–A533. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Nakajima, Hiroshi, Hiroshi Taniguchi, Kenji Imai, Hajime Ariga, Kirk A. Ludwig, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Acoustic stress attenuates gastric migrating motor complex, without affecting motilin release, via inhibiting sympatho-vagal balance in conscious dogs.” In Gastroenterology, 134:A538–A538. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Nakajima, Hitoshi, Erito Mochiki, Hiroshi Taniguchi, Hajime Ariga, Cindy Chen, Kirk A. Ludwig, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Interdigestive migrating motor complex is regulated by the interaction between motilin and 5-HT of the duodenal mucosa in conscious dogs.” In Gastroenterology, 134:A689–A689. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Taniguchi, Hiroshi, Hajime Ariga, Cindy Chen, Jun Zheng, Kirk A. Ludwig, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Gastroduodenal interdigestive phase III-Like contractions are mediated via ghrelin, while intestinal interdigestive phase III-Like contractions are mediated via 5-HT in conscious rats.” In Gastroenterology, 134:A686–A686. W B SAUNDERS CO-ELSEVIER INC, 2008.
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    • Ariga, H., K. Tsukamoto, K. Imai, E. Mochiki, C. Chen, C. Mantyh, T. N. Pappas, and T. Takahashi. “The mechanism of accelerated gastric emptying in early stage of diabetes: enhanced manifestation of postprandial antro-pyloric coordination in STZ-induced diabetic rats.” In Neurogastroenterology and Motility, 19:434–434. BLACKWELL PUBLISHING, 2007.
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    • Ariga, Hajime, Cindy Chen, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “The mechanism of accelerated gastric emptying in the early stage of diabetes: Endogenous ghrelin plays an important role in enhanced manifestation of Antro-PYLORIC coordination in STZ-Induced diabetic rats. Coordination in STZ-Induced diabetic rats.” In Gastroenterology, 132:A719–A719. W B SAUNDERS CO-ELSEVIER INC, 2007.
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    • Ariga, Hajime, Yukiomi Nakade, Cindy Chen, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Ghrelin administration causes early manifestation of postprandial antro-pyloric coordinations, resulting in rapid gastric emptying in rats.” In Gastroenterology, 132:A720–A720. W B SAUNDERS CO-ELSEVIER INC, 2007.
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    • Imai, Kenji, Cindy Chen, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Site-specific effects of electroacupuncturc (EA) on gastric motility in conscious rats; Stimulatory effect of EA at ST-36 is mediated via vagal pathways, while inhibitory effect of EA at ST-25 is mediated via sympathetic pathways.” In Gastroenterology, 132:A719–A719. W B SAUNDERS CO-ELSEVIER INC, 2007.
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    • Tsukamoto, Kiyoshi, Ento Mochiki, Hajime Ariga, Cindy Chen, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Luminally released 5-HT from EC cells plays an important role to regulate colonic motility in rats.” In Gastroenterology, 132:A715–A715. W B SAUNDERS CO-ELSEVIER INC, 2007.
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    • Fuente, S. de la, R. Manson, K. Ludwig, and C. Mantyh. “Preoperative chemoradiation for rectal cancer reduces lymph node harvest in proctectomy specimens.” In Diseases of the Colon & Rectum, 50:712–712, 2007.
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    • Mantyh, C., K. Tsukamoto, K. Ludwig, T. Pappas, and T. Takahashi. “5-HT release in the proximal colon is modulated by stress-induced brain CRF receptors in rats.” In Diseases of the Colon & Rectum, 50:787–787, 2007.
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    • Czito, B., C. Willett, H. Hurwitz, M. Morse, D. Tyler, K. Ludwig, C. Mantyh, G. Vaccaro, S. Taylor, and J. Bendell. “2097.” In International Journal of Radiation Oncology*Biology*Physics, 66:S263–S263. Elsevier BV, 2006. https://doi.org/10.1016/j.ijrobp.2006.07.501.
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    • Mantyh, C. R. “Meta-analysis of colonic reserviors versus straight coloanal anastomosis after anterior resection.” In Diseases of the Colon and Rectum, 49:1249–50, 2006. https://doi.org/10.1007/s10350-005-0239-x.
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    • Fisher, Deborah A., Christopher R. Mantyh, Michael A. Morse, Richard G. Prosnitz, Gregory R. Samsa, and Meenal B. Patwardhan. “Quality measures for colorectal cancer diagnosis: A systematic review.” In Gastroenterology, 130:A616–A616. W B SAUNDERS CO-ELSEVIER INC, 2006.
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    • Nakade, Yukiomi, Kiyoshi Tsukamoto, Constant Masere, Kirk Ludwig, Christopher R. Mantyh, Theodore N. Pappas, and Toku Takahashi. “Central glucagon like peptide-1 accelerates colonic transit via a central CRF and peripheral parasympathetic pathway in conscious rats.” In Gastroenterology, 130:A90–A90. W B SAUNDERS CO-ELSEVIER INC, 2006.
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    • Masere, Constant S., Cindy Chen, Yukiomi Nakade, Kiyoshi Tsukamoto, Christopher Mantyh, Kirk Ludwig, Theodore N. Pappas, and Toku Takahashi. “Chronic restraint stress causes NO more stimulation of colonic motor function in conscious rats.” In Gastroenterology, 130:A445–A445, 2006.
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    • Morse, M., R. Prosnitz, C. Mantyh, D. Fisher, G. Samsa, D. McCrory, K. Cline, R. Gray, and M. Patwardhan. “Measurement of quality of care for adjuvant chemotherapy of colorectal cancer.” In Journal of Clinical Oncology, 24:318S-318S, 2006.
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    • Tsukamoto, Kiyoshi, Yukiomi Nakade, Christopher Mantyh, Kirk Ludwig, Theodore N. Pappas, and Toku Takahashi. “Peripherally administered CRF stimulates colonic motility via central CRF receptors and vagal pathways in conscious rats.” In Gastroenterology, 130:A89–A89, 2006.
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    • Kalady, M. F., C. R. Mantyh, and K. A. Ludwig. “Routine contrast imaging of low pelvic anastomosis before defunctioning ileostomy closure: Is it necessary?” In Diseases of the Colon & Rectum, 48:623–24. SPRINGER, 2005.
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    • Kalady, M. F., M. W. Onaitis, C. R. Mantyh, D. S. Tyler, and K. A. Ludwig. “Coloanal anastomotic integrity after total mesorectal excision is not compromised by preoperative chemoradiation for rectal cancer.” In Diseases of the Colon & Rectum, 48:601–2. SPRINGER, 2005.
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    • Lee, W. Y., T. Takahashi, C. R. Mantyh, T. N. Pappas, and K. A. Ludwig. “Surgical autonomic denervation results in altered colonic motility.” In Diseases of the Colon & Rectum, 48:683–683. SPRINGER, 2005.
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    • Takahashi, T., H. Fukuda, D. Tsuchida, C. R. Mantyh, T. N. Pappas, and K. A. Ludwig. “Inhibition of sympathetic pathways improves postoperative ileus in the upper and lower gastrointestinal tract.” In Diseases of the Colon & Rectum, 48:606–7. SPRINGER, 2005.
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    • Fujino, K., S. de la Fuente, S. R. Vigna, and C. R. Mantyh. “Attenuation of acid-induced esophagitis in mice deficient in the vanilloid receptor subtype-1.” In Gastroenterology, 126:A48–A48. W B SAUNDERS CO, 2004.
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    • Fujino, K., Y. Takami, S. De La Fuente, K. A. Ludwig, S. R. Vigna, and C. R. Mantyh. “Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-induced colitis.” In Gastroenterology, 126:A772–A772. W B SAUNDERS CO, 2004.
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    • Fukuda, H., D. Tsuchida, C. R. Mantyh, T. N. Pappas, and T. Takahashi. “Intestinal manipulation causes postoperative ileus via an inhibitory sympathetic efferent pathway.” In Gastroenterology, 126:A223–A223. W B SAUNDERS CO, 2004.
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    • Fukuda, H., K. Suenaga, K. Uemura, D. Tsuchida, C. R. Mantyh, T. N. Papas, G. A. Hicks, and T. Takahashi. “The selective Mu opioid receptor antagonist, alvimopan, accelerates gastrointestinal transit in a rodent model of postoperative ileus.” In Gastroenterology, 126:A641–A641. W B SAUNDERS CO, 2004.
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    • Kalady, M. F., R. C. Fields, S. Klein, K. C. Nielson, C. R. Mantyh, and K. A. Ludwig. “Loop ileostomy closure at an ambulatory surgery facility: A safe and cost-effective alternative to routine hospitalization (vol 46, pg 486, 2003).” In Diseases of the Colon & Rectum, 46:903–903. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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    • De La Fuente, Sebastian G., Kazunori Fujino, Theodore N. Pappas, and Christopher R. Mantyh. “Vanilloid receptor subtype-1 deficient mice are protected from Clostridium difficile toxin-a-induced intestinal edema.” In Gastroenterology, 124:A475–A475. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)82403-4.
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    • Fujino, Kazunori, Sebastian G. De La Fuente, Theodore N. Pappas, and Christopher R. Mantyh. “Dextran sulfate sodium-induced enterocolitis is attenuated in vanilloid receptor-1 knockout mice.” In Gastroenterology, 124:A141–42. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)80700-x.
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    • Kalady, M. F., R. C. Fields, K. B. Wilkins, M. W. Onaitis, D. S. Tyler, C. R. Mantyh, and K. Ludwig. “Routine contrast imaging of low pelvic anastomosis before temporary stoma closure: Lack of clinical impact on patient management.” In Gastroenterology, 123:29–29. W B SAUNDERS CO, 2002.
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    • Kihara, N., S. Fukumoto, S. De La Fuente, T. Takahashi, T. Pappas, and C. R. Mantyh. “Local application of capsazepine, a vanilloid recepter-1 (VR-1) antagonist, inhibits dextran sulfate sodium-induced colitis in rats.” In Gastroenterology, 122:A393–94. W B SAUNDERS CO, 2002.
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    • De La Fuente, S., M. R. Gottfried, D. C. Lawson, M. Harris, C. Mantyh, and T. Pappas. “Histologic evaluation after full-thickness gastric defect repair with porcine small intestine submucosa graft.” In Gastroenterology, 123:21–21, 2002.
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    • Fukumoto, S., T. Kono, M. Voss, S. Eubanks, N. Kihara, C. Mantyh, T. Pappas, and T. Takahashi. “Intraluminal short chain fatty acids accelerate colonic transit by promoting migrating contractions in conscious rats.” In Gastroenterology, 122:A409–A409, 2002.
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    • Mantyh, Christopher R., Douglas C. McVey, and Steven R. Vigna. “Extrinsic denervation inhibits clostridium difficile toxin A-induced enteritis.” In Gastroenterology, 118:A882–A882. Elsevier BV, 2000. https://doi.org/10.1016/s0016-5085(00)85666-8.
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    • Mantyh, C. R., J. R. Ghilardi, S. D. Rogers, S. R. Vigna, T. N. Pappas, and P. W. Mantyh. “Differential release of substance P in the spinal cord in response to visceral versus somatosensory pain.” In Gastroenterology, 110:A1097–A1097, 1996.
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    • CIACCIA, D., S. R. BRAZER, D. C. LAWSON, C. R. MANTYH, R. A. LIDDLE, and T. N. PAPPAS. “CHOLECYSTOKININ IS A PHYSIOLOGICAL MEDIATOR OF FAT-INDUCED LOWER ESOPHAGEAL SPHINCTER RELAXATION.” In Gastroenterology, 108:A584–A584, 1995. https://doi.org/10.1016/0016-5085(95)26648-8.
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    • LAPP, J. A., C. R. MANTYH, D. M. LYERLY, S. R. VIGNA, and T. N. PAPPAS. “ALTERATIONS IN ENTERIC NEURON SUBSTANCE-P RECEPTORS IN CLOSTRIDIUM-DIFFICILE TOXIN-A-INDUCED COLITIS.” In Gastroenterology, 108:A858–A858, 1995. https://doi.org/10.1016/0016-5085(95)27738-2.
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    • MANTYH, C. R., R. R. BOLLINGER, S. R. VIGNA, and T. N. PAPPAS. “DIFFERENTIAL EXPRESSION OF SUBSTANCE-P RECEPTORS IN CROHNS-DISEASE AND ULCERATIVE-COLITIS.” In Gastroenterology, 108:A870–A870, 1995.
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    • MANTYH, C. R., S. R. VIGNA, J. E. MAGGIO, P. W. MANTYH, R. B. SARTOR, and T. N. PAPPAS. “SUBSTANCE-P RECEPTOR EXPRESSION AND RECEPTOR ANTAGONISTS IN HUMAN INFLAMMATORY BOWEL-DISEASE (IBD) AND RAT ENTEROCOLITIS.” In Gastroenterology, 106:A728–A728, 1994.
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    • MANTYH, C. R., S. R. VIGNA, and T. N. PAPPAS. “LOCALIZATION OF CCK(A) AND CCK(B)/GASTRIN RECEPTORS IN THE CANINE UPPER GASTROINTESTINAL-TRACT.” In Gastroenterology, 106:A825–A825, 1994.
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    • BACAY, A. C., C. R. MANTYH, A. H. COHEN, P. W. MANTYH, and L. G. FINE. “GLOMERULAR ATRIAL NATRIURETIC FACTOR (ANF) RECEPTORS IN PRIMARY GLOMERULOPATHIES - STUDIES ON HUMAN RENAL BIOPSIES.” In Kidney International, 35:207–207. BLACKWELL SCIENCE INC, 1989.
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    • VIGNA, S. R., C. R. MANTYH, J. E. MAGGIO, A. H. SOLL, and P. W. MANTYH. “SUBSTANCE-P RECEPTORS ON CANINE CHIEF CELLS.” In Gastroenterology, 94:A480–A480. W B SAUNDERS CO, 1988.
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    • MANTYH, C. R., T. GATES, R. P. ZIMMERMAN, L. KRUGER, J. E. MAGGIO, S. R. VIGNA, A. I. BASBAUM, J. LEVINE, and P. W. MANTYH. “ALTERATIONS IN THE DENSITY OF RECEPTOR-BINDING SITES FOR SENSORY NEUROPEPTIDES IN THE SPINAL-CORD OF ARTHRITIC RATS.” In Arthritic Rat as a Model of Clinical Pain, edited by J. M. BESSON and G. GUILBAUD, 837:139–52. ELSEVIER SCIENCE PUBL B V, 1988.
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    • MANTYH, P. W., C. R. MANTYH, A. S. GIRAUD, A. H. SOLL, J. H. WALSH, and S. R. VIGNA. “LOCALIZATION OF SPECIFIC BINDING-SITES FOR BOMBESIN AND RELATED PEPTIDES IN THE GASTROINTESTINAL-TRACT.” In Regulatory Peptides, 19:125–125. ELSEVIER SCIENCE BV, 1987.
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    • Welton, M. L., C. R. Mantyh, T. S. Gates, P. Popper, S. R. Vigna, J. E. Maggio, E. Passaro, and P. W. Mantyh. “Localization of bombesin receptors in human gastrointestinal tract using quantitative receptor autoradiography.” In Regulatory Peptides, 19:144–144. Elsevier BV, 1987. https://doi.org/10.1016/0167-0115(87)90165-0.
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    • FINE, L. G., C. R. MANTYH, A. COHEN, and P. W. MANTYH. “USE OF THE RENAL BIOPSY TO PROBE THE PATHOPHYSIOLOGY OF HUMAN RENAL-DISEASE - GLOMERULAR BINDING OF ATRIAL-NATRIURETIC-PEPTIDE (ANP).” In Kidney International, 31:198–198. BLACKWELL SCIENCE INC, 1987.
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    • ABOLS, I. A., C. R. MANTYH, and P. W. MANTYH. “NEUROPEPTIDES AND THEIR RECEPTORS IN HUMAN SPINAL-CORD AND DORSAL-ROOT GANGLION NEURONS.” In Neurology, 36:260–260. LIPPINCOTT-RAVEN PUBL, 1986.
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    • KRUGER, L., C. STERNINI, N. BRECHA, C. MANTYH, and P. MANTYH. “CGRP IMMUNOREACTIVITY AND RECEPTOR DISTRIBUTION IN THE RAT CENTRAL-NERVOUS-SYSTEM.” In Anatomical Record, 214:A69–A69, 1986.
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