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Christopher Ritchie Mantyh

Professor of Surgery
Surgical Oncology
Box 3117 Med Ctr, Durham, NC 27710
7676 Hosp North Hafs Building, Durham, NC 27710

Overview


Neurogenic inflammation
Ulcerative colitis
Crohn's disease
Neuropeptides
Receptors
Vanilloid receptor
Substance P
Intestinal motility
Colorectal cancer outcomes
Colon cancer
Rectal cancer

Current Appointments & Affiliations


Professor of Surgery · 2015 - Present Surgical Oncology, Surgery
Vice Chair of Clinical Operations · 2023 - Present Surgery, Clinical Science Departments
Member of the Duke Cancer Institute · 1999 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Perioperative and Oncologic Outcomes of Hepatic Arterial Infusion (HAI) Pump Chemotherapy for Patients with Unresectable Colorectal Liver Metastases at an Expanding HAI Program.

Conference Ann Surg Oncol · February 2025 BACKGROUND: Hepatic arterial infusion (HAI) is an established treatment for patients with unresectable colorectal liver metastases (uCRLM). Until recently, HAI was only performed at a limited number of centers. We previously reported early outcomes suggest ... Full text Link to item Cite

The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal Article Anesth Analg · January 1, 2025 BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of ... Full text Link to item Cite

Social Vulnerability Index and Survivorship after Colorectal Cancer Resection.

Journal Article J Am Coll Surg · April 1, 2024 BACKGROUND: Race and socioeconomic status incompletely identify patients with colorectal cancer (CRC) at the highest risk for screening, treatment, and mortality disparities. Social vulnerability index (SVI) was designed to delineate neighborhoods requirin ... Full text Link to item Cite
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Recent Grants


Inhibition of CaMKK2 sensitizes rectal cancers to radiation therapy

ResearchCollaborator · Awarded by National Institutes of Health · 2021 - 2022

Prevention of Surgical Site Infection using Statistical Process Control Charts

ResearchCo Investigator · Awarded by Agency for Healthcare Research and Quality · 2015 - 2020

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Education, Training & Certifications


University of Wisconsin, Madison · 1991 M.D.