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Overview


Research Interest:

  • Host-pathogen Interactions
  • Molecular Biology
  • Antimicrobial Resistance
  • Drug Development

Current Duke Appointments & Affiliations


Recent Scholarly Works


High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape.

Journal article Cell Genom · February 11, 2026 We present a collection of 17 high-quality long-read inbred mouse strain genomes with complete annotation (contig N50s of 0.8-33.9 Mbp). This collection includes 12 widely used classical laboratory strains and 5 wild-derived strains. We have resolved previ ... Full text Link to item Cite

Violacein-Loaded Outer Membrane Vesicles from <i>Salmonella enterica</i> Exhibit Potent Anti-Melanoma Activity <i>in Vitro</i> and <i>in Vivo</i>.

Journal article ACS biomaterials science & engineering · October 2025 Violacein exhibits antitumor activity, indicating potential for future clinical application. However, an efficient delivery system is required for the clinical use of this hydrophobic compound. Effective delivery systems can enhance the solubility and bioa ... Full text Cite

Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity.

Journal article PLoS Biol · September 2025 Tuberculosis (TB) outcomes vary widely, from asymptomatic infection to mortality, yet most animal models do not recapitulate human phenotypic and genotypic variation. The genetically diverse Collaborative Cross mouse panel models distinct facets of TB dise ... Full text Link to item Cite
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