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Marina Tuyishime

Medical Instructor in the Department of Surgery
Surgery, Surgical Sciences
27 Alexandria Way, Duke@RTP, Durham, NC 27703

Current Appointments & Affiliations


Medical Instructor in the Department of Surgery · 2023 - Present Surgery, Surgical Sciences, Surgery

Recent Publications


Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge.

Journal Article Vaccines (Basel) · February 24, 2025 Background: The RV144 trial in Thailand is the only HIV-1 vaccine efficacy trial to date to demonstrate any efficacy. Genetic signatures suggested that antibodies targeting the variable loop 2 (V2) of the HIV-1 envelope played an important protective role. ... Full text Link to item Cite

AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.

Journal Article Nat Med · October 2023 The main barrier to HIV cure is a persistent reservoir of latently infected CD4+ T cells harboring replication-competent provirus that fuels rebound viremia upon antiretroviral therapy (ART) interruption. A leading approach to target this reservoir involve ... Full text Link to item Cite

Functional consequences of allotypic polymorphisms in human immunoglobulin G subclasses.

Journal Article Immunogenetics · February 2023 Heritable polymorphisms within the human IgG locus, collectively termed allotypes, have often been linked by statistical associations, but rarely mechanistically, to a wide range of disease states. One potential explanation for these associations is that I ... Full text Cite
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Recent Grants


Targeting CD180 to induce anti-KSHV response in nonhuman primates

ResearchPrincipal Investigator · Awarded by Oregon Health & Science University · 2024 - 2029

Quantitative Methods for HIV/AIDS Research

Inst. Training Prgm or CMETraining Faculty · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028

SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens

ResearchResearch Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

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Education, Training & Certifications


Drexel University · 2016 Ph.D.
Richard Stockton College · 2009 B.S.