Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.H.S., Duke University School of Medicine 2010
  • M.D., Duke University 1997
• 

  Previous Appointments & Affiliations

  • Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1997 - 2017
  • Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2016
  • Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2011 - 2016
  • Assistant Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2007 - 2011
• Research
• 

  Selected Grants

  • National Longitudinal Outcomes Following Surgical Therapy for Lung Cancer awarded by Society of Thoracic Surgeons 2014 - 2019
  • Targeting Integrator Kinases in Lung Cancer Metastasis awarded by Free to Breathe 2015 - 2018
  • Anti-CTGF Therapy for Squamous Cell Lung Cancer awarded by National Institutes of Health 2016 - 2017
  • K-RAS mutant lung adenocarcinoma treatment awarded by AATS Graham Foundation 2014 - 2016
  • Novel druggable pathway required for lung cancer progression and metastasis awarded by Uniting Against Lung Cancer 2014 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Burt, B. M., and M. Onaitis. “Robotic Ivor-Lewis esophagectomy in 15 steps.” Jtcvs Techniques, January 1, 2023. https://doi.org/10.1016/j.xjtc.2023.03.007.
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    • Onaitis, M. “Discussion.” Journal of Thoracic and Cardiovascular Surgery, January 1, 2023. https://doi.org/10.1016/j.jtcvs.2023.03.013.
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    • Onaitis, Mark. “Discussion.” J Thorac Cardiovasc Surg 165, no. 1 (January 2023): 349–50. https://doi.org/10.1016/j.jtcvs.2022.08.041.
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    • Erwin, Philip A., Andy C. Lee, Usman Ahmad, Mara Antonoff, Andrew Arndt, Leah Backhus, Mark Berry, et al. “Consensus for Thoracoscopic Lower Lobectomy: Essential Components and Targets for Simulation.” Ann Thorac Surg 114, no. 5 (November 2022): 1895–1901. https://doi.org/10.1016/j.athoracsur.2021.09.033.
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    • Wood, Douglas E., Ella A. Kazerooni, Denise Aberle, Abigail Berman, Lisa M. Brown, Georgie A. Eapen, David S. Ettinger, et al. “NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022.” J Natl Compr Canc Netw 20, no. 7 (July 2022): 754–64. https://doi.org/10.6004/jnccn.2022.0036.
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    • Smith, Ryan J., Hongpan Zhang, Shengen Shawn Hu, Theodora Yung, Roshane Francis, Lilian Lee, Mark W. Onaitis, Peter B. Dirks, Chongzhi Zang, and Tae-Hee Kim. “Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions.” Nat Commun 13, no. 1 (May 26, 2022): 2965. https://doi.org/10.1038/s41467-022-30624-w.
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    • Boys, Josh, and Mark Onaitis. “Commentary: You can't hit what you can't see: Esophageal adenocarcinoma with signet ring cells.” J Thorac Cardiovasc Surg 162, no. 5 (November 2021): 1415–16. https://doi.org/10.1016/j.jtcvs.2020.09.090.
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    • Wilshire, Candice L., Sandra L. Blitz, Carson C. Fuller, Jens C. Rückert, Feng Li, Robert J. Cerfolio, Asem F. Ghanim, et al. “Minimally invasive thymectomy for myasthenia gravis favours left-sided approach and low severity class.” Eur J Cardiothorac Surg 60, no. 4 (October 22, 2021): 898–905. https://doi.org/10.1093/ejcts/ezab014.
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    • Bazhenova, Lyudmila, James Urbanic, and Mark Onaitis. “Commentary: Epidermal growth factor receptor mutations in resectable lung cancer: What is the prognostic importance?” J Thorac Cardiovasc Surg 162, no. 3 (September 2021): 676–77. https://doi.org/10.1016/j.jtcvs.2020.06.109.
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    • Horgan, Santiago, and Mark Onaitis. “Commentary: Minimally invasive esophagectomy: Steady progress.” J Thorac Cardiovasc Surg 162, no. 3 (September 2021): 707–8. https://doi.org/10.1016/j.jtcvs.2021.02.054.
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    • Sienicki, Elise, and Mark Onaitis. “Commentary: New players in epidermal growth factor receptor tyrosine kinase inhibitor resistance.” J Thorac Cardiovasc Surg 162, no. 2 (August 2021): 474–75. https://doi.org/10.1016/j.jtcvs.2020.04.096.
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    • Broderick, Ryan C., Arielle M. Lee, Rachel R. Blitzer, Beiqun Zhao, Jenny Lam, Joslin N. Cheverie, Bryan J. Sandler, et al. “It's not always too late: a case for minimally invasive salvage esophagectomy.” Surg Endosc 35, no. 8 (August 2021): 4700–4711. https://doi.org/10.1007/s00464-020-07937-2.
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    • Bryan, Darren S., Mark K. Ferguson, Mara B. Antonoff, Leah M. Backhus, Thomas J. Birdas, Shanda H. Blackmon, Daniel J. Boffa, et al. “Consensus for Thoracoscopic Left Upper Lobectomy-Essential Components and Targets for Simulation.” Ann Thorac Surg 112, no. 2 (August 2021): 436–42. https://doi.org/10.1016/j.athoracsur.2020.06.152.
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    • Brown, Lisa M., Dylan P. Thibault, Andrzej S. Kosinski, David T. Cooke, Mark W. Onaitis, Henning A. Gaissert, and Patrick S. Romano. “Readmission After Lobectomy for Lung Cancer: Not All Complications Contribute Equally.” Ann Surg 274, no. 1 (July 1, 2021): e70–79. https://doi.org/10.1097/SLA.0000000000003561.
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    • Medbery, Rachel L., Felix G. Fernandez, Andrzej S. Kosinski, Betty C. Tong, Anthony P. Furnary, Liqi Feng, Mark Onaitis, et al. “Costs Associated With Lobectomy for Lung Cancer: An Analysis Merging STS and Medicare Data.” Ann Thorac Surg 111, no. 6 (June 2021): 1781–90. https://doi.org/10.1016/j.athoracsur.2020.08.073.
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    • Cowper, Patricia A., Liqi Feng, Andrzej S. Kosinski, Betty C. Tong, Robert H. Habib, Joe B. Putnam, Mark W. Onaitis, et al. “Initial and Longitudinal Cost of Surgical Resection for Lung Cancer.” Ann Thorac Surg 111, no. 6 (June 2021): 1827–33. https://doi.org/10.1016/j.athoracsur.2020.07.048.
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    • Boys, Josh, and Mark Onaitis. “Commentary: Predicting intrathoracic pathologic concordance in patients with metastatic nonseminomatous germ cell tumor is clearly unclear.” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 871–72. https://doi.org/10.1016/j.jtcvs.2020.11.132.
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    • Onaitis, Mark. “Commentary: Survival after small cell lung cancer resection: Small opportunity?” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 773–74. https://doi.org/10.1016/j.jtcvs.2020.11.069.
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    • Onaitis, Mark. “Commentary: Induction immunotherapy for esophageal cancer: A safe start.” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 844. https://doi.org/10.1016/j.jtcvs.2020.12.027.
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    • Golts, Eugene, and Mark Onaitis. “Commentary: Ischemia reperfusion-Looking ahead.” J Thorac Cardiovasc Surg 161, no. 2 (February 2021): e124–25. https://doi.org/10.1016/j.jtcvs.2019.12.010.
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    • Fetten, Katharina, and Mark Onaitis. “Commentary: Octogenarians and Esophageal Cancer, Are We Afraid to Treat, or Are We Missing Information?” Semin Thorac Cardiovasc Surg 33, no. 3 (2021): 893–94. https://doi.org/10.1053/j.semtcvs.2020.10.037.
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    • Patel, Sandip Pravin, and Mark Onaitis. “Commentary: Induction Immunotherapy: Intriguing Initiative for Investigation.” Semin Thorac Cardiovasc Surg 33, no. 3 (2021): 858–59. https://doi.org/10.1053/j.semtcvs.2021.02.013.
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    • Onaitis, Mark W., Anthony P. Furnary, Andrzej S. Kosinski, Liqi Feng, Daniel Boffa, Betty C. Tong, Patricia Cowper, et al. “Equivalent Survival Between Lobectomy and Segmentectomy for Clinical Stage IA Lung Cancer.” Ann Thorac Surg 110, no. 6 (December 2020): 1882–91. https://doi.org/10.1016/j.athoracsur.2020.01.020.
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    • Onaitis, Mark. “Discussion.” J Thorac Cardiovasc Surg 160, no. 4 (October 2020): 1073. https://doi.org/10.1016/j.jtcvs.2019.12.116.
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    • Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.
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    • Boys, Joshua, and Mark Onaitis. “Commentary: Breaking down non-small cell lung cancer tumor microenvironment heterogeneity and predicting response to immune checkpoint inhibitors.” J Thorac Cardiovasc Surg 159, no. 4 (April 2020): 1612–13. https://doi.org/10.1016/j.jtcvs.2019.11.097.
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    • Garman, Katherine S., Teminioluwa A. Ajayi, Harold J. Boutte, Shih-Ting Chiu, Richard J. von Furstenberg, Benjamin R. Lloyd, Cecelia Zhang, Mark W. Onaitis, Shein-Chung Chow, and Shannon J. McCall. “Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma.” Plos One 15, no. 7 (2020): e0235906. https://doi.org/10.1371/journal.pone.0235906.
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    • Galant-Swafford, Jessica, Matthew Light, Mark W. Onaitis, Stephen A. Rawlings, Joshua Fierer, and Judd W. Landsberg. “A 37-Year-Old Man With Pleuritic Chest Pain.” Chest 156, no. 1 (July 2019): e15–21. https://doi.org/10.1016/j.chest.2019.02.002.
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    • Huang, L., Y. Shen, and M. Onaitis. “Comparative study of anatomic lung resection by robotic vs. Video-assisted thoracoscopic surgery.” Journal of Thoracic Disease 11, no. 4 (April 1, 2019): 1243–50. https://doi.org/10.21037/jtd.2019.03.104.
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    • Fernandez, Felix G., Andrzej S. Kosinski, Betty C. Tong, Anthony P. Furnary, Liqi Feng, Mark Onaitis, Daniel Boffa, et al. “Lack of correlation between short- and long-term performance after lung cancer surgery.” J Thorac Cardiovasc Surg 157, no. 4 (April 2019): 1633-1643.e3. https://doi.org/10.1016/j.jtcvs.2018.09.141.
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    • Yang, Chi-Fu Jeffrey, Shivani A. Shah, Belle K. Lin, Keith W. VanDusen, Derek Y. Chan, Wendy D. Tan, David N. Ranney, Morgan L. Cox, Thomas A. D’Amico, and Mark F. Berry. “Right-Sided Versus Left-Sided Pneumonectomy After Induction Therapy for Non-Small Cell Lung Cancer.” Ann Thorac Surg 107, no. 4 (April 2019): 1074–81. https://doi.org/10.1016/j.athoracsur.2018.10.009.
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    • Wolfe, Gil I., Henry J. Kaminski, Inmaculada B. Aban, Greg Minisman, Hui-Chien Kuo, Alexander Marx, Philipp Ströbel, et al. “Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.” Lancet Neurol 18, no. 3 (March 2019): 259–68. https://doi.org/10.1016/S1474-4422(18)30392-2.
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    • Tong, Betty C., Sunghee Kim, Andrzej Kosinski, Mark W. Onaitis, Daniel J. Boffa, Robert H. Habib, Joe B. Putnam, et al. “Penetration, Completeness, and Representativeness of The Society of Thoracic Surgeons General Thoracic Surgery Database for Lobectomy.” Ann Thorac Surg 107, no. 3 (March 2019): 897–902. https://doi.org/10.1016/j.athoracsur.2018.07.059.
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    • Boffa, Daniel J., Andrzej S. Kosinski, Anthony P. Furnary, Sunghee Kim, Mark W. Onaitis, Betty C. Tong, Patricia A. Cowper, et al. “Minimally Invasive Lung Cancer Surgery Performed by Thoracic Surgeons as Effective as Thoracotomy.” J Clin Oncol 36, no. 23 (August 10, 2018): 2378–85. https://doi.org/10.1200/JCO.2018.77.8977.
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    • Iglesias-Bartolome, Ramiro, Akihiko Uchiyama, Alfredo A. Molinolo, Loreto Abusleme, Stephen R. Brooks, Juan Luis Callejas-Valera, Dean Edwards, et al. “Transcriptional signature primes human oral mucosa for rapid wound healing.” Sci Transl Med 10, no. 451 (July 25, 2018). https://doi.org/10.1126/scitranslmed.aap8798.
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    • Upham, Trevor C., and Mark W. Onaitis. “Video-assisted thoracoscopic surgery versus robot-assisted thoracoscopic surgery versus thoracotomy for early-stage lung cancer.” J Thorac Cardiovasc Surg 156, no. 1 (July 2018): 365–68. https://doi.org/10.1016/j.jtcvs.2018.02.064.
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    • Fernandez, Felix G., Andrzej S. Kosinski, Anthony P. Furnary, Mark Onaitis, Sunghee Kim, Robert H. Habib, Betty C. Tong, et al. “Differential effects of operative complications on survival after surgery for primary lung cancer.” J Thorac Cardiovasc Surg 155, no. 3 (March 2018): 1254-1264.e1. https://doi.org/10.1016/j.jtcvs.2017.09.149.
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    • Cheng, Xinghua, Mark W. Onaitis, Thomas A. D’amico, and Haiquan Chen. “Minimally Invasive Thoracic Surgery 3.0: Lessons Learned From the History of Lung Cancer Surgery.” Ann Surg 267, no. 1 (January 2018): 37–38. https://doi.org/10.1097/SLA.0000000000002405.
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    • Tirrell, T., and M. Onaitis. “Lymph node assessment and survival: We still have work to do.” Journal of Thoracic Disease 10, no. 1 (January 1, 2018): 15–16. https://doi.org/10.21037/jtd.2017.12.112.
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    • Onaitis, Mark W., Anthony P. Furnary, Andrzej S. Kosinski, Sunghee Kim, Daniel Boffa, Betty C. Tong, Patricia Cowper, et al. “Prediction of Long-Term Survival After Lung Cancer Surgery for Elderly Patients in The Society of Thoracic Surgeons General Thoracic Surgery Database.” Ann Thorac Surg 105, no. 1 (January 2018): 309–16. https://doi.org/10.1016/j.athoracsur.2017.06.071.
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    • Boyer, Matthew J., Christina D. Williams, David H. Harpole, Mark W. Onaitis, Michael J. Kelley, and Joseph K. Salama. “Improved Survival of Stage I Non-Small Cell Lung Cancer: A VA Central Cancer Registry Analysis.” J Thorac Oncol 12, no. 12 (December 2017): 1814–23. https://doi.org/10.1016/j.jtho.2017.09.1952.
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    • Gaissert, Henning A., Felix G. Fernandez, Traves Crabtree, William R. Burfeind, Mark S. Allen, Mark I. Block, Paul H. Schipper, et al. “The Society of Thoracic Surgeons General Thoracic Surgery Database: 2017 Update on Research.” Ann Thorac Surg 104, no. 5 (November 2017): 1450–55. https://doi.org/10.1016/j.athoracsur.2017.08.060.
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    • Asselin-Labat, Marie-Liesse, Rishi Rampersad, Xia Xu, Matthew E. Ritchie, Jacob Michalski, Lingling Huang, and Mark W. Onaitis. “High-LET Radiation Increases Tumor Progression in a K-Ras-Driven Model of Lung Adenocarcinoma.” Radiat Res 188, no. 5 (November 2017): 562–70. https://doi.org/10.1667/RR14794.1.
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    • Karhausen, Jörn A., Alan M. Smeltz, Igor Akushevich, Mary Cooter, Mihai V. Podgoreanu, Mark Stafford-Smith, Susan M. Martinelli, Manuel L. Fontes, and Miklos D. Kertai. “Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery.” Anesth Analg 125, no. 4 (October 2017): 1129–39. https://doi.org/10.1213/ANE.0000000000002187.
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    • Cerfolio, Robert, Brian E. Louie, Alexander S. Farivar, Mark Onaitis, and Bernard J. Park. “Consensus statement on definitions and nomenclature for robotic thoracic surgery.” J Thorac Cardiovasc Surg 154, no. 3 (September 2017): 1065–69. https://doi.org/10.1016/j.jtcvs.2017.02.081.
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    • Roberts, Sheridan L., Xin-Peng Dun, Robin D. S. Doddrell, Thomas Mindos, Louisa K. Drake, Mark W. Onaitis, Francesca Florio, et al. “Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.” Development 144, no. 17 (September 1, 2017): 3114–25. https://doi.org/10.1242/dev.150656.
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    • Boffa, Daniel, Felix G. Fernandez, Sunghee Kim, Andrzej Kosinski, Mark W. Onaitis, Patricia Cowper, Jeffrey P. Jacobs, Cameron D. Wright, Joe B. Putnam, and Anthony P. Furnary. “Surgically Managed Clinical Stage IIIA-Clinical N2 Lung Cancer in The Society of Thoracic Surgeons Database.” Ann Thorac Surg 104, no. 2 (August 2017): 395–403. https://doi.org/10.1016/j.athoracsur.2017.02.031.
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    • Gu, Jing Jin, Clay Rouse, Xia Xu, Jun Wang, Mark W. Onaitis, and Ann Marie Pendergast. “Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis.” Jci Insight 1, no. 21 (December 22, 2016): e89647. https://doi.org/10.1172/jci.insight.89647.
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    • Gulack, Brian C., Chi-Fu Jeffrey Yang, Paul J. Speicher, Babatunde A. Yerokun, Betty C. Tong, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, Matthew G. Hartwig, and Mark F. Berry. “A Risk Score to Assist Selecting Lobectomy Versus Sublobar Resection for Early Stage Non-Small Cell Lung Cancer.” Ann Thorac Surg 102, no. 6 (December 2016): 1814–20. https://doi.org/10.1016/j.athoracsur.2016.06.032.
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    • Gaissert, Henning A., Felix G. Fernandez, Mark S. Allen, William R. Burfeind, Mark I. Block, James M. Donahue, John D. Mitchell, et al. “The Society of Thoracic Surgeons General Thoracic Surgery Database: 2016 Update on Research.” Ann Thorac Surg 102, no. 5 (November 2016): 1444–51. https://doi.org/10.1016/j.athoracsur.2016.09.014.
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    • Onaitis, Mark, and Bernard Park. “Teaching robotic surgery: Making progress.” J Thorac Cardiovasc Surg 152, no. 4 (October 2016): 950–51. https://doi.org/10.1016/j.jtcvs.2016.07.039.
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    • Boyer, Matthew J., Lin Gu, Xiaofei Wang, Chris R. Kelsey, David S. Yoo, Mark W. Onaitis, Frank R. Dunphy, Jeffrey Crawford, Neal E. Ready, and Joseph K. Salama. “Toxicity of definitive and post-operative radiation following ipilimumab in non-small cell lung cancer.” Lung Cancer 98 (August 2016): 76–78. https://doi.org/10.1016/j.lungcan.2016.05.014.
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    • Yerokun, Babatunde A., Zhifei Sun, Chi-Fu Jeffrey Yang, Brian C. Gulack, Paul J. Speicher, Mohamed A. Adam, Thomas A. D’Amico, et al. “Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis.” Ann Thorac Surg 102, no. 2 (August 2016): 416–23. https://doi.org/10.1016/j.athoracsur.2016.02.078.
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    • Onaitis, Mark W., and Joseph Salama. “Surgery versus stereotactic body radiation therapy for operable stage I non-small cell lung cancer: Can we achieve equipoise?” J Thorac Cardiovasc Surg 152, no. 1 (July 2016): 1–2. https://doi.org/10.1016/j.jtcvs.2016.04.016.
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    • Yang, Chi-Fu Jeffrey, Robert Ryan Meyerhoff, Nicholas Ryan Mayne, Terry Singhapricha, Christopher B. Toomey, Paul J. Speicher, Matthew G. Hartwig, et al. “Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1615–23. https://doi.org/10.1093/ejcts/ezv428.
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    • Yang, Chi-Fu Jeffrey, Syed M. Adil, Kevin L. Anderson, Robert Ryan Meyerhoff, Ryan S. Turley, Matthew G. Hartwig, David H. Harpole, et al. “Impact of patient selection and treatment strategies on outcomes after lobectomy for biopsy-proven stage IIIA pN2 non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1607–13. https://doi.org/10.1093/ejcts/ezv431.
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    • Fernandez, Felix G., Anthony P. Furnary, Andrzej S. Kosinski, Mark W. Onaitis, Sunghee Kim, Daniel Boffa, Patricia Cowper, Jeffrey P. Jacobs, Cameron D. Wright, and Joe B. Putnam. “Longitudinal Follow-up of Lung Cancer Resection From the Society of Thoracic Surgeons General Thoracic Surgery Database in Patients 65 Years and Older.” Ann Thorac Surg 101, no. 6 (June 2016): 2067–76. https://doi.org/10.1016/j.athoracsur.2016.03.034.
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    • Yang, Chi-Fu Jeffrey, Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Xiaofei Wang, Matthew G. Hartwig, Mark W. Onaitis, et al. “Role of Adjuvant Therapy in a Population-Based Cohort of Patients With Early-Stage Small-Cell Lung Cancer.” J Clin Oncol 34, no. 10 (April 1, 2016): 1057–64. https://doi.org/10.1200/JCO.2015.63.8171.
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    • Yang, Chi-Fu Jeffrey, Zhifei Sun, Paul J. Speicher, Shakir M. Saud, Brian C. Gulack, Matthew G. Hartwig, David H. Harpole, et al. “Use and Outcomes of Minimally Invasive Lobectomy for Stage I Non-Small Cell Lung Cancer in the National Cancer Data Base.” Ann Thorac Surg 101, no. 3 (March 2016): 1037–42. https://doi.org/10.1016/j.athoracsur.2015.11.018.
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    • Kang, Xiaozheng, Hongliang Liu, Mark W. Onaitis, Zhensheng Liu, Kouros Owzar, Younghun Han, Li Su, et al. “Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls.” Carcinogenesis 37, no. 3 (March 2016): 280–89. https://doi.org/10.1093/carcin/bgw014.
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    • Oprea, Adriana D., Manuel L. Fontes, Mark W. Onaitis, and Miklos D. Kertai. “Comparison Between the 2007 and 2014 American College of Cardiology/American Heart Association Guidelines on Perioperative Evaluation for Noncardiac Surgery.” J Cardiothorac Vasc Anesth 29, no. 6 (December 2015): 1639–50. https://doi.org/10.1053/j.jvca.2015.04.021.
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    • Yang, Chi-Fu Jeffrey, Brian C. Gulack, Lin Gu, Paul J. Speicher, Xiaofei Wang, David H. Harpole, Mark W. Onaitis, Thomas A. D’Amico, Mark F. Berry, and Matthew G. Hartwig. “Adding radiation to induction chemotherapy does not improve survival of patients with operable clinical N2 non-small cell lung cancer.” J Thorac Cardiovasc Surg 150, no. 6 (December 2015): 1484–92. https://doi.org/10.1016/j.jtcvs.2015.06.062.
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    • Yang, Chi-Fu J., Derek Y. Chan, Brian C. Gulack, Paul J. Speicher, Mark W. Onaitis, Betty C. Tong, Thomas A. D’Amico, David Harpole, Mark F. Berry, and Matthew G. Hartwig. “Wedge Resection vs Segmentectomy for Patients with T1A N0 Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S242–S242.
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    • Yang, Chi-Fu J., Derek Y. Chan, Brian C. Gulack, Paul J. Speicher, Matthew G. Hartwig, Mark F. Berry, Betty C. Tong, Mark W. Onaitis, Thomas A. D’Amico, and David Harpole. “Survival after Surgery for pN1 and pN2 Small Cell Lung Cancer: A Comparison with Surgical Treatment of Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S399–400.
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    • Yang, Chi-Fu J., Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Mark W. Onaitis, Matthew G. Hartwig, Betty C. Tong, Mark F. Berry, Thomas A. D’Amico, and David Harpole. “Long-Term Survival after Surgery for Pathologic N1 and N2 Small Cell Lung Cancer: A Comparison with Nonoperative Management.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S193–94.
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    • Yang, Chi-Fu J., Syed M. Adil, Robert R. Meyerhoff, Kevin L. Anderson, Sameer A. Hirji, David Harpole, Betty C. Tong, et al. “Impact of Radiation on Recurrence Patterns and Survival for Patients Undergoing Lobectomy for Stage IIIA-pN2 Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S573–S573.
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    • Tang, Paul, Mark Onaitis, Jeffrey G. Gaca, Carmelo A. Milano, Mark Stafford-Smith, and Donald Glower. “Right Minithoracotomy Versus Median Sternotomy for Mitral Valve Surgery: A Propensity Matched Study.” Ann Thorac Surg 100, no. 2 (August 2015): 575–81. https://doi.org/10.1016/j.athoracsur.2015.04.027.
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    • Berry, Mark F., Chi-Fu Jeffrey Yang, Matthew G. Hartwig, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Impact of Pulmonary Function Measurements on Long-Term Survival After Lobectomy for Stage I Non-Small Cell Lung Cancer.” Ann Thorac Surg 100, no. 1 (July 2015): 271–76. https://doi.org/10.1016/j.athoracsur.2015.02.076.
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    • Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Outcomes after treatment of 17,378 patients with locally advanced (T3N0-2) non-small-cell lung cancer.” Eur J Cardiothorac Surg 47, no. 4 (April 2015): 636–41. https://doi.org/10.1093/ejcts/ezu270.
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    • Xiao, Lin, Dae Joong Kim, Clayton L. Davis, James V. McCann, James M. Dunleavey, Alissa K. Vanderlinden, Nuo Xu, et al. “Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition.” Cancer Res 75, no. 7 (April 1, 2015): 1244–54. https://doi.org/10.1158/0008-5472.CAN-14-1616.
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    • Coleman, Brooke K., Lesley H. Curtis, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Adjuvant chemotherapy after resection of N1 non-small cell lung cancer: differential impact of new evidence on physician and patient decisions.” J Thorac Dis 7, no. 3 (March 2015): 243–51. https://doi.org/10.3978/j.issn.2072-1439.2015.01.42.
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    • Hanna, Jennifer M., Loretta Erhunmwunsee, Mark Berry, Thomas D’Amico, and Mark Onaitis. “The prognostic importance of the number of dissected lymph nodes after induction chemoradiotherapy for esophageal cancer.” Ann Thorac Surg 99, no. 1 (January 2015): 265–69. https://doi.org/10.1016/j.athoracsur.2014.08.073.
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    • Kara, Hasan Volkan, Mohan K. Mallipeddi, Jeffrey Javidfar, and Mark W. Onaitis. “Benign emptying of the postpneumonectomy space.” Lung India 32, no. 6 (2015): 614–15. https://doi.org/10.4103/0970-2113.168136.
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    • Linden, Philip A., Thomas A. D’Amico, Yaron Perry, Paramita Saha-Chaudhuri, Shubin Sheng, Sunghee Kim, and Mark Onaitis. “Quantifying the safety benefits of wedge resection: a society of thoracic surgery database propensity-matched analysis.” Ann Thorac Surg 98, no. 5 (November 2014): 1705–11. https://doi.org/10.1016/j.athoracsur.2014.06.017.
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    • Xu, Xia, Lingling Huang, Christopher Futtner, Brian Schwab, Rishi R. Rampersad, Yun Lu, Thomas A. Sporn, Brigid L. M. Hogan, and Mark W. Onaitis. “The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.” Genes Dev 28, no. 17 (September 1, 2014): 1929–39. https://doi.org/10.1101/gad.243717.114.
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    • Speicher, Paul J., Asvin M. Ganapathi, Brian R. Englum, Matthew G. Hartwig, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Induction therapy does not improve survival for clinical stage T2N0 esophageal cancer.” J Thorac Oncol 9, no. 8 (August 2014): 1195–1201. https://doi.org/10.1097/JTO.0000000000000228.
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    • Burt, Bryan M., Andrzej S. Kosinski, Joseph B. Shrager, Mark W. Onaitis, and Tracey Weigel. “Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal.” J Thorac Cardiovasc Surg 148, no. 1 (July 2014): 19–28. https://doi.org/10.1016/j.jtcvs.2014.03.007.
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    • Hanna, Jennifer M., and Mark W. Onaitis. “Robotic benign esophageal procedures.” Thorac Surg Clin 24, no. 2 (May 2014): 223–vii. https://doi.org/10.1016/j.thorsurg.2014.02.004.
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    • Huang, Lingling, and Mark Onaitis. “Minimally invasive and robotic Ivor Lewis esophagectomy.” J Thorac Dis 6 Suppl 3, no. Suppl 3 (May 2014): S314–21. https://doi.org/10.3978/j.issn.2072-1439.2014.04.32.
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    • Huang, Lingling, Vonn Walter, D Neil Hayes, and Mark Onaitis. “Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.” Clin Cancer Res 20, no. 6 (March 15, 2014): 1566–75. https://doi.org/10.1158/1078-0432.CCR-13-2195.
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    • Speicher, Paul J., Asvin M. Ganapathi, Brian R. Englum, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Survival in the elderly after pneumonectomy for early-stage non-small cell lung cancer: a comparison with nonoperative management.” J Am Coll Surg 218, no. 3 (March 2014): 439–49. https://doi.org/10.1016/j.jamcollsurg.2013.12.005.
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    • Liu, Kuancan, Ming Jiang, Yun Lu, Hao Chen, Jun Sun, Shaoping Wu, Wei-Yao Ku, et al. “Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells.” Cell Stem Cell 12, no. 3 (March 7, 2013): 304–15. https://doi.org/10.1016/j.stem.2013.01.007.
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    • Villamizar, Nestor R., Marcus Darrabie, Jennifer Hanna, Mark W. Onaitis, Betty C. Tong, Thomas A. D’Amico, and Mark F. Berry. “Impact of T status and N status on perioperative outcomes after thoracoscopic lobectomy for lung cancer.” J Thorac Cardiovasc Surg 145, no. 2 (February 2013): 514–20. https://doi.org/10.1016/j.jtcvs.2012.10.039.
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    • Hanna, Jennifer M., and Mark W. Onaitis. “Cell of origin of lung cancer.” J Carcinog 12 (2013): 6. https://doi.org/10.4103/1477-3163.109033.
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    • Tang, Paul, Mark Onaitis, Bhargavi Desai, Jeffrey G. Gaca, Carmelo A. Milano, Mark Stafford-Smith, and Donald D. Glower. “Minithoracotomy versus sternotomy for mitral surgery in patients with chronic renal impairment: a propensity-matched study.” Innovations (Phila) 8, no. 5 (2013): 325–31. https://doi.org/10.1097/IMI.0000000000000020.
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    • Hanna, J. M., and M. W. Onaitis. “Technique of Video-Assisted Thoracoscopic Chest Wall Resection.” Operative Techniques in Thoracic and Cardiovascular Surgery 17, no. 4 (December 1, 2012): 280–91. https://doi.org/10.1053/j.optechstcvs.2012.11.002.
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    • Ceppa, DuyKhanh P., Andrzej S. Kosinski, Mark F. Berry, Betty C. Tong, David H. Harpole, John D. Mitchell, Thomas A. D’Amico, and Mark W. Onaitis. “Thoracoscopic lobectomy has increasing benefit in patients with poor pulmonary function: a Society of Thoracic Surgeons Database analysis.” Ann Surg 256, no. 3 (September 2012): 487–93. https://doi.org/10.1097/SLA.0b013e318265819c.
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    • Boffa, Daniel J., Andrzej S. Kosinski, Subroto Paul, John D. Mitchell, and Mark Onaitis. “Lymph node evaluation by open or video-assisted approaches in 11,500 anatomic lung cancer resections.” Ann Thorac Surg 94, no. 2 (August 2012): 347–53. https://doi.org/10.1016/j.athoracsur.2012.04.059.
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    • Boffa, Daniel J., Sidharta Gangadharan, Michael Kent, Faraz Kerendi, Mark Onaitis, Edward Verrier, and Eric Roselli. “Self-perceived video-assisted thoracic surgery lobectomy proficiency by recent graduates of North American thoracic residencies.” Interact Cardiovasc Thorac Surg 14, no. 6 (June 2012): 797–800. https://doi.org/10.1093/icvts/ivr098.
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    • Berry, Mark F., Mark W. Onaitis, Betty C. Tong, Stafford S. Balderson, David H. Harpole, and Thomas A. D’Amico. “Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection.” Eur J Cardiothorac Surg 41, no. 4 (April 2012): 888–92. https://doi.org/10.1093/ejcts/ezr150.
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    • Shah, Asad A., Michael E. Barfield, Chris R. Kelsey, Mark W. Onaitis, Betty Tong, David Harpole, Thomas A. D’Amico, and Mark F. Berry. “Outcomes after surgical management of synchronous bilateral primary lung cancers.” Ann Thorac Surg 93, no. 4 (April 2012): 1055–60. https://doi.org/10.1016/j.athoracsur.2011.12.070.
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    • Xu, Xia, Jason R. Rock, Yun Lu, Christopher Futtner, Brian Schwab, Justin Guinney, Brigid L. M. Hogan, and Mark W. Onaitis. “Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.” Proc Natl Acad Sci U S A 109, no. 13 (March 27, 2012): 4910–15. https://doi.org/10.1073/pnas.1112499109.
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    • Ceppa, Duykhanh P., Ian J. Welsby, Tracy Y. Wang, Mark W. Onaitis, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark F. Berry. “Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection.” Ann Thorac Surg 92, no. 6 (December 2011): 1971–76. https://doi.org/10.1016/j.athoracsur.2011.07.052.
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    • Atkins, B Zane, Mark W. Onaitis, Kelley A. Hutcheson, Keith Kaye, Rebecca P. Petersen, and Walter G. Wolfe. “Does method of sternal repair influence long-term outcome of postoperative mediastinitis?” Am J Surg 202, no. 5 (November 2011): 565–67. https://doi.org/10.1016/j.amjsurg.2011.06.013.
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    • Higgins, Kristin A., Junzo P. Chino, Neal Ready, Mark W. Onaitis, Mark F. Berry, Thomas A. D’Amico, and Chris R. Kelsey. “Persistent N2 disease after neoadjuvant chemotherapy for non-small-cell lung cancer.” J Thorac Cardiovasc Surg 142, no. 5 (November 2011): 1175–79. https://doi.org/10.1016/j.jtcvs.2011.07.059.
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    • Meltzer, Eric B., William T. Barry, Thomas A. D’Amico, Robert D. Davis, Shu S. Lin, Mark W. Onaitis, Lake D. Morrison, Thomas A. Sporn, Mark P. Steele, and Paul W. Noble. “Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principle.” Bmc Med Genomics 4 (October 5, 2011): 70. https://doi.org/10.1186/1755-8794-4-70.
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    • Hartwig, Matthew G., Deverick J. Anderson, Mark W. Onaitis, Shekur Reddy, Laurie D. Snyder, Shu S. Lin, and R Duane Davis. “Fundoplication after lung transplantation prevents the allograft dysfunction associated with reflux.” Ann Thorac Surg 92, no. 2 (August 2011): 462–68. https://doi.org/10.1016/j.athoracsur.2011.04.035.
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    • D’Amico, Thomas A., Betty C. Tong, Mark F. Berry, William R. Burfeind, and Mark W. Onaitis. “Incorporating research into thoracic surgery practice.” Thorac Surg Clin 21, no. 3 (August 2011): 369–77. https://doi.org/10.1016/j.thorsurg.2011.04.004.
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    • D’Amico, Thomas A., Joyce Niland, Rizvan Mamet, Carrie Zornosa, Elisabeth U. Dexter, and Mark W. Onaitis. “Efficacy of mediastinal lymph node dissection during lobectomy for lung cancer by thoracoscopy and thoracotomy.” Ann Thorac Surg 92, no. 1 (July 2011): 226–31. https://doi.org/10.1016/j.athoracsur.2011.03.134.
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    • Berry, Mark F., Mark W. Onaitis, Betty C. Tong, David H. Harpole, and Thomas A. D’Amico. “A model for morbidity after lung resection in octogenarians.” Eur J Cardiothorac Surg 39, no. 6 (June 2011): 989–94. https://doi.org/10.1016/j.ejcts.2010.09.038.
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    • Swaminathan, Madhav, Alina Nicoara, Barbara G. Phillips-Bute, Nicolas Aeschlimann, Carmelo A. Milano, G Burkhard Mackensen, Mihai V. Podgoreanu, et al. “Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery.” Ann Thorac Surg 91, no. 6 (June 2011): 1844–50. https://doi.org/10.1016/j.athoracsur.2011.02.008.
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    • Onaitis, Mark, Thomas A. D’Amico, Cheryl P. Clark, Justin Guinney, David H. Harpole, and Emma L. Rawlins. “A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.” Ann Thorac Surg 91, no. 4 (April 2011): 1046–50. https://doi.org/10.1016/j.athoracsur.2010.12.054.
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    • Pepek, Joseph M., Junzo P. Chino, Lawrence B. Marks, Thomas A. D’amico, David S. Yoo, Mark W. Onaitis, Neal E. Ready, Jessica L. Hubbs, Jessamy Boyd, and Chris R. Kelsey. “How well does the new lung cancer staging system predict for local/regional recurrence after surgery?: A comparison of the TNM 6 and 7 systems.” J Thorac Oncol 6, no. 4 (April 2011): 757–61. https://doi.org/10.1097/JTO.0b013e31821038c0.
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    • Walsh, Mark D., Anthony D. Bruno, Mark W. Onaitis, Detlev Erdmann, Walter G. Wolfe, Eric M. Toloza, and L Scott Levin. “The role of intrathoracic free flaps for chronic empyema.” Ann Thorac Surg 91, no. 3 (March 2011): 865–68. https://doi.org/10.1016/j.athoracsur.2010.10.019.
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    • Hanna, Jennifer M., and Mark W. Onaitis. “Human lung stem cells: has the future arrived?” Semin Thorac Cardiovasc Surg 23, no. 4 (2011): 259–60. https://doi.org/10.1053/j.semtcvs.2011.10.009.
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    • Berry, Mark F., B Zane Atkins, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia.” J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1266–71. https://doi.org/10.1016/j.jtcvs.2010.08.038.
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    • Onaitis, Mark, Thomas D’Amico, Yue Zhao, Sean O’Brien, and David Harpole. “Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database.” Ann Thorac Surg 90, no. 2 (August 2010): 368–74. https://doi.org/10.1016/j.athoracsur.2010.03.100.
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    • Lu, Yun, Christopher Futtner, Jason R. Rock, Xia Xu, Walter Whitworth, Brigid L. M. Hogan, and Mark W. Onaitis. “Evidence that SOX2 overexpression is oncogenic in the lung.” Plos One 5, no. 6 (June 10, 2010): e11022. https://doi.org/10.1371/journal.pone.0011022.
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    • Berry, Mark F., Nestor R. Villamizar-Ortiz, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Pulmonary function tests do not predict pulmonary complications after thoracoscopic lobectomy.” Ann Thorac Surg 89, no. 4 (April 2010): 1044–51. https://doi.org/10.1016/j.athoracsur.2009.12.065.
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    • Paul, Subroto, Nasser K. Altorki, Shubin Sheng, Paul C. Lee, David H. Harpole, Mark W. Onaitis, Brendon M. Stiles, Jeffrey L. Port, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database.” J Thorac Cardiovasc Surg 139, no. 2 (February 2010): 366–78. https://doi.org/10.1016/j.jtcvs.2009.08.026.
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    • Tong, Betty C., Jennifer Hanna, Eric M. Toloza, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, and William R. Burfeind. “Outcomes of video-assisted thoracoscopic decortication.” Ann Thorac Surg 89, no. 1 (January 2010): 220–25. https://doi.org/10.1016/j.athoracsur.2009.09.021.
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    • Stevenson, Marvaretta, William Mostertz, Chaitanya Acharya, William Kim, Kelli Walters, William Barry, Kristin Higgins, et al. “Characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.” Clin Cancer Res 15, no. 24 (December 15, 2009): 7553–61. https://doi.org/10.1158/1078-0432.CCR-09-1939.
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    • Berry, Mark F., Jennifer Hanna, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Risk factors for morbidity after lobectomy for lung cancer in elderly patients.” Ann Thorac Surg 88, no. 4 (October 2009): 1093–99. https://doi.org/10.1016/j.athoracsur.2009.06.012.
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    • Rock, Jason R., Mark W. Onaitis, Emma L. Rawlins, Yun Lu, Cheryl P. Clark, Yan Xue, Scott H. Randell, and Brigid L. M. Hogan. “Basal cells as stem cells of the mouse trachea and human airway epithelium.” Proc Natl Acad Sci U S A 106, no. 31 (August 4, 2009): 12771–75. https://doi.org/10.1073/pnas.0906850106.
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    • Villamizar, Nestor R., Marcus D. Darrabie, William R. Burfeind, Rebecca P. Petersen, Mark W. Onaitis, Eric Toloza, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy.” J Thorac Cardiovasc Surg 138, no. 2 (August 2009): 419–25. https://doi.org/10.1016/j.jtcvs.2009.04.026.
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    • Erhunmwunsee, Loretta, and Mark W. Onaitis. “Smoking cessation and the success of lung cancer surgery.” Curr Oncol Rep 11, no. 4 (July 2009): 269–74. https://doi.org/10.1007/s11912-009-0038-y.
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    • Onaitis, Mark W., Rebecca P. Petersen, John C. Haney, Leonard Saltz, Bernard Park, Raja Flores, Nabil Rizk, et al. “Prognostic factors for recurrence after pulmonary resection of colorectal cancer metastases.” Ann Thorac Surg 87, no. 6 (June 2009): 1684–88. https://doi.org/10.1016/j.athoracsur.2009.03.034.
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    • Onaitis, M. W., J. Haney, R. Petersen, L. B. Saltz, R. M. Flores, N. Rizk, M. S. Bains, et al. “Factors influencing outcome after pulmonary resection for colorectal cancer (CRC) metastases in the current era.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 4024.
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    • Onaitis, Mark W., Rebecca P. Petersen, Stafford S. Balderson, Eric Toloza, William R. Burfeind, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients.” Ann Surg 244, no. 3 (September 2006): 420–25. https://doi.org/10.1097/01.sla.0000234892.79056.63.
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    • Onaitis, Mark, Kirk Ludwig, Anthony Perez-Tamayo, Marcia Gottfried, Linda Russell, Phillip Shadduck, Theodore Pappas, Hilliard F. Seigler, and Douglas S. Tyler. “The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions.” J Surg Oncol 94, no. 3 (September 1, 2006): 194–202. https://doi.org/10.1002/jso.20591.
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    • Aloia, Thomas A., Elizabeth Grubbs, Mark Onaitis, Paul J. Mosca, Tsung-Yen Cheng, Hilliard Seigler, and Douglas S. Tyler. “Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response.” Arch Surg 140, no. 11 (November 2005): 1115–20. https://doi.org/10.1001/archsurg.140.11.1115.
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    • Abdel-Wahab, Zeinab, Robin Cisco, Jens Dannull, Tomio Ueno, Omar Abdel-Wahab, Matthew F. Kalady, Mark W. Onaitis, Douglas S. Tyler, and Scott K. Pruitt. “Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses.” J Surg Res 124, no. 2 (April 2005): 264–73. https://doi.org/10.1016/j.jss.2004.10.002.
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    • Safford, Shawn D., R Edward Coleman, Jon P. Gockerman, Joseph Moore, Jerome Feldman, Mark W. Onaitis, Douglas S. Tyler, and John A. Olson. “Iodine-131 metaiodobenzylguanidine treatment for metastatic carcinoid. Results in 98 patients.” Cancer 101, no. 9 (November 1, 2004): 1987–93. https://doi.org/10.1002/cncr.20592.
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    • Kalady, Matthew F., Bercedis Peterson, John Baillie, Mark W. Onaitis, Omar I. Abdul-Wahab, James K. Howden, Paul S. Jowell, et al. “Pancreatic duct strictures: identifying risk of malignancy.” Ann Surg Oncol 11, no. 6 (June 2004): 581–88. https://doi.org/10.1245/ASO.2004.03.070.
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    • Kalady, Matthew F., Mark W. Onaitis, Sirisha Emani, Zeinab Abdul-Wahab, Scott K. Pruitt, and Douglas S. Tyler. “Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific antipancreatic cancer T cells.” J Gastrointest Surg 8, no. 2 (February 2004): 175–81. https://doi.org/10.1016/j.gassur.2003.11.003.
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    • Kalady, Matthew F., Mark W. Onaitis, Sirisha Emani, Zeinab Abdel-Wahab, Douglas S. Tyler, and Scott K. Pruitt. “Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity.” J Surg Res 116, no. 1 (January 2004): 24–31. https://doi.org/10.1016/j.jss.2003.09.003.
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    • Onaitis, Mark W., Matthew F. Kalady, Sirisha Emani, Zeinab Abdel-Wahab, Douglas S. Tyler, and Scott K. Pruitt. “CD40 ligand is essential for generation of specific cytotoxic T cell responses in RNA-pulsed dendritic cell immunotherapy.” Surgery 134, no. 2 (August 2003): 300–305. https://doi.org/10.1067/msy.2003.240.
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    • Onaitis, Mark, Michael Morse, Herbert Hurwitz, Peggy Cotton, Douglas Tyler, Pierre Clavien, and Bryan Clary. “Adjuvant hepatic arterial chemotherapy following metastasectomy in patients with isolated liver metastases.” Ann Surg 237, no. 6 (June 2003): 782–88. https://doi.org/10.1097/01.SLA.0000071561.76384.19.
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    • Onaitis, M., R. White, and D. Tyler. “Carcinoid tumors of the gastrointestinal tract. A review and the Duke University institutional overview.” Minerva Chir 58, no. 1 (February 2003): 1–8.
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    • Daniels, Larkin J., Stafford S. Balderson, Mark W. Onaitis, and Thomas A. D’Amico. “Thoracoscopic lobectomy: a safe and effective strategy for patients with stage I lung cancer.” Ann Thorac Surg 74, no. 3 (September 2002): 860–64. https://doi.org/10.1016/s0003-4975(02)03764-5.
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    • Onaitis, Mark, Matthew F. Kalady, Scott Pruitt, and Douglas S. Tyler. “Dendritic cell gene therapy.” Surg Oncol Clin N Am 11, no. 3 (July 2002): 645–60. https://doi.org/10.1016/s1055-3207(02)00027-3.
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    • Kalady, Matthew F., Mark W. Onaitis, Karen M. Padilla, Sirisha Emani, Douglas S. Tyler, and Scott K. Pruitt. “Enhanced dendritic cell antigen presentation in RNA-based immunotherapy.” J Surg Res 105, no. 1 (June 1, 2002): 17–24. https://doi.org/10.1006/jsre.2002.6435.
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    • Kypson, Alan P., Mark W. Onaitis, Jerome M. Feldman, and Douglas S. Tyler. “Carcinoid and chylous ascites: an unusual association.” J Gastrointest Surg 6, no. 5 (2002): 781–83. https://doi.org/10.1016/s1091-255x(02)00014-8.
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    • Onaitis, M. W., R. B. Noone, R. Fields, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival.” Ann Surg Oncol 8, no. 10 (December 2001): 801–6. https://doi.org/10.1007/s10434-001-0801-2.
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    • Onaitis, M. W., P. M. Kirshbom, T. Z. Hayward, F. J. Quayle, J. M. Feldman, H. F. Seigler, and D. S. Tyler. “Gastrointestinal carcinoids: characterization by site of origin and hormone production.” Ann Surg 232, no. 4 (October 2000): 549–56. https://doi.org/10.1097/00000658-200010000-00010.
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    • Kirshbom, P. M., A. R. Kherani, M. W. Onaitis, A. Hata, T. E. Kehoe, C. Feldman, J. M. Feldman, and D. S. Tyler. “Foregut carcinoids: a clinical and biochemical analysis.” Surgery 126, no. 6 (December 1999): 1105–10. https://doi.org/10.1067/msy.2099.101430.
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    • Kirshbom, P. M., A. R. Kherani, M. W. Onaitis, J. M. Feldman, and D. S. Tyler. “Carcinoids of unknown origin: comparative analysis with foregut, midgut, and hindgut carcinoids.” Surgery 124, no. 6 (December 1998): 1063–70. https://doi.org/10.1067/msy.1998.93105.
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  • Book Sections

    • Onaitis, M. W., and T. A. D’amico. “Molecular biology of lung cancer.” In Cardiothoracic Surgery Review, 984–86, 2012.
    • Harpole, D. H., and M. Onaitis. “Present concepts in the molecular biology of lung cancer.” In General Thoracic Surgery: Seventh Edition, 2–2:3577–91, 2011.

  • Other Articles

    • Onaitis, Mark W., and Thomas A. D’Amico. “Modern Management of Pulmonary Metastases.” Thorac Surg Clin, February 2016. https://doi.org/10.1016/j.thorsurg.2015.10.001.
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    • Onaitis, Mark. “Invited Commentary.” Ann Thorac Surg, September 2015. https://doi.org/10.1016/j.athoracsur.2015.05.005.
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    • Onaitis, Mark. “Invited commentary.” Ann Thorac Surg, November 2013. https://doi.org/10.1016/j.athoracsur.2013.06.001.
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    • Stevenson, Marvaretta, William Mostertz, Chaitanya R. Acharya, William Kim, Kelli Walters, William Barry, Kristin Higgins, et al. “Retraction: characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.” Clin Cancer Res, March 15, 2012. https://doi.org/10.1158/1078-0432.CCR-12-0337.
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    • Welsby, Ian J., Barbara Phillips-Bute, and Mark W. Onaitis. “Invited commentary.” Ann Thorac Surg, July 2010. https://doi.org/10.1016/j.athoracsur.2010.04.053.
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    • Friesen, S. R., M. W. Onaitis, A. Frilling, K. A. Kelly, E. L. Kaplan, J. B. D. Mark, and H. T. Debas. “Gastrointestinal carcinoids: Characterization by site of origin and hormone production - Discussion.” Annals of Surgery. LIPPINCOTT WILLIAMS & WILKINS, October 1, 2000.
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  • Conference Papers

    • Iglesias-Bartolome, R., A. Uchiyama, R. Graf, A. A. Molinolo, L. Abusleme, S. R. Brooks, J. Callejas-Valera, et al. “1395 Unique transcriptional signature primes oral mucosa for rapid wound healing in humans.” In Journal of Investigative Dermatology, 138:S237–S237. Elsevier BV, 2018. https://doi.org/10.1016/j.jid.2018.03.1413.
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    • Yi, John, Jeffrey Melson Clarke, Patrick Healy, Xiaofei F. Wang, Debra Shoemaker, Mark W. Onaitis, Chelsae Dumbauld, et al. “Immune profiling of circulating T cells and TILs following neoadjuvant ipilimumab and chemotherapy in non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, 35:26–26. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.7_suppl.26.
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    • Yang, Chi-Fu Jeffrey, Derek Y. Chan, Babatunde Yerokun, Xiaofei F. Wang, Betty Caroline Tong, Thomas A. D’Amico, Mark W. Onaitis, Matthew G. Hartwig, Mark F. Berry, and David Harpole. “Surgery versus optimal medical management of early-stage small cell lung cancer.” In Journal of Clinical Oncology, 34:8511–8511. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.8511.
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    • Xu, Xia, Rishi Rampersad, Brigid L. M. Hogan, and Mark W. Onaitis. “Mechanism of Notch and Sox2 in Kras driven lung adenocarcinoma in type II cells∗.” In Journal of Thoracic Oncology, 11:S54–S54. Elsevier BV, 2016. https://doi.org/10.1016/j.jtho.2015.12.090.
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    • Mallipeddi, Mohan K., Walid R. Eltaraboulsi, Adam R. Shoffner, Ibtehaj A. Naqvi, Thomas A. D’Amico, Mark W. Onaitis, and Mark F. Berry. “When should surgeons begin surveillance with CT scans after lobectomy for stage 1A non-small cell lung cancer?” In Journal of Clinical Oncology, 32:7549–7549. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.7549.
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    • Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Association of adjuvant chemotherapy with improved survival after esophagectomy without induction therapy for node-positive adenocarinoma.” In Journal of Clinical Oncology, 32:4077–4077. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.4077.
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    • Erhunmwunsee, L., B. R. Englum, T. A. D’Amico, M. W. Onaitis, and M. F. Berry. “Impact of Pre-treatment Imaging on Survival of Esophagectomy after Induction Therapy for Esophageal Cancer: Who Should be Given the Benefit of Doubt?” In Annals of Surgical Oncology, 21:S151–S151. SPRINGER, 2014.
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    • Mallipeddi, M. K., W. R. Eltaraboulsi, A. R. Shoffner, I. A. Naqvi, T. A. D’Amico, M. W. Onaitis, and M. F. Berry. “The Impact of Surveillance after Lobectomy for Stage IA Non-small Cell Lung Cancer.” In Annals of Surgical Oncology, 21:S153–54. SPRINGER, 2014.
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    • Higgins, Kristin A., Neal E. Ready, Thomas A. D’amico, Mark W. Onaitis, Jeffrey Crawford, Robert Clough, Mark F. Berry, et al. “PERSISTENT N2 DISEASE AFTER NEOADJUVANT CHEMOTHERAPY-NOW WHAT?” In Journal of Thoracic Oncology, 6:S1572–S1572. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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    • Onaitis, Mark W. “CASE PRESENTATION: SMALL T1 SUBPLEURAL LUNG LESION IN THE RIGHT UPPER LOBE, INCIDENTALLY FOUND.” In Journal of Thoracic Oncology, 6:S155–S155. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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    • Pepek, J. M., J. P. Chino, M. W. Onaitis, L. B. Marks, N. Ready, J. Crawford, T. A. D’Amico, J. L. Hubbs, and C. R. Kelsey. “Does the revised TNM staging system for lung cancer better estimate actuarial rates of local/regional recurrence after surgery?” In Journal of Clinical Oncology, 28:7072–7072. American Society of Clinical Oncology (ASCO), 2010. https://doi.org/10.1200/jco.2010.28.15_suppl.7072.
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    • Rock, Jason R., Emma L. Rawlins, Mark W. Onaitis, and Brigid L. Hogan. “Basal cells as stem cells of the mouse trachea and human conducting airways.” In Developmental Biology, 331:503–503. Elsevier BV, 2009. https://doi.org/10.1016/j.ydbio.2009.05.438.
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    • Erhunmwunsee, Loretta, Yun Lu, Xiaoyan Luo, David H. Harpole, Brigid L. M. Hogan, and Mark W. Onaitis. “Basal cells in lung cancer.” In Journal of the American College of Surgeons, 207:S30–S30. Ovid Technologies (Wolters Kluwer Health), 2008. https://doi.org/10.1016/j.jamcollsurg.2008.06.053.
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    • Onaitis, M. W., J. Haney, R. Petersen, L. B. Saltz, R. M. Flores, N. Rizk, M. S. Bains, et al. “Factors influencing outcome after pulmonary resection for colorectal cancer (CRC) metastases in the current era.” In Journal of Clinical Oncology, 26:4024–4024. American Society of Clinical Oncology (ASCO), 2008. https://doi.org/10.1200/jco.2008.26.15_suppl.4024.
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    • Kalady, M. F., M. W. Onaitis, C. R. Mantyh, D. S. Tyler, and K. A. Ludwig. “Coloanal anastomotic integrity after total mesorectal excision is not compromised by preoperative chemoradiation for rectal cancer.” In Diseases of the Colon & Rectum, 48:601–2. SPRINGER, 2005.
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    • Kalady, Mathhew F., Mark W. Onaitis, Zeinab Abdul-Wahab, Sirisha Emani, Scott K. Pruitt, and Douglas S. Tyler. “Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific anti-pancreatic cancer T cells.” In Gastroenterology, 124:A788–A788. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)83977-x.
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    • Onaitis, Mark W., Douglas S. Tyler, Edward Coleman, Peggy Cotton, and Bryan M. Clary. “Improved survival in patients with colorectal metastases to the liver undergoing preoperative FDG-PET.” In Gastroenterology, 124:A825–A825. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)84160-4.
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    • Safford, S. D., R. E. Coleman, J. P. Gockerman, J. Moore, J. Feldman, M. W. Onaitis, D. S. Tyler, and J. A. Olson. “I-131-meta-iodobenzylguanidine treatment for metastatic carcinoid tumors in 98 patients.” In Annals of Surgical Oncology, 10:S12–S12. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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    • Kalady, M. F., R. C. Fields, K. B. Wilkins, M. W. Onaitis, D. S. Tyler, C. R. Mantyh, and K. Ludwig. “Routine contrast imaging of low pelvic anastomosis before temporary stoma closure: Lack of clinical impact on patient management.” In Gastroenterology, 123:29–29. W B SAUNDERS CO, 2002.
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    • Kalady, M. F., M. W. Onaitis, J. K. Howden, J. Baillie, P. S. Jowell, M. S. Branch, T. N. Pappas, and D. S. Tyler. “Pancreatic duct strictures without an associated common bile duct stricture: Identifying risk of malignancy.” In Annals of Surgical Oncology, 9:S12–13. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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    • Kalady, M. F., D. C. White, M. W. Onaitis, E. Coleman, H. F. Seigler, and D. Tyler. “Validation of delayed sentinel lymph node mapping for melanoma.” In Cancer Journal, 7:521–22. JONES AND BARTLETT PUBLISHERS, 2001.
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    • Daniels, Larkin J., Elizabeth K. O’Halloran, Mark W. Onaitis, and Steve Eubanks. “Laparoscopic heller myotomy as an effective and durable treatment for achalasia: The Duke University Experience.” In Gastroenterology, 120:A479–A479. Elsevier BV, 2001. https://doi.org/10.1016/s0016-5085(08)82373-6.
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