Mark William Onaitis
Adjunct Associate Professor in the Department of Surgery
Mouse Models of Foregut Malignancies
Normal Tissue and Cancer Stem Cells
Risk Prediction in Thoracic Malignancies
Normal Tissue and Cancer Stem Cells
Risk Prediction in Thoracic Malignancies
Current Appointments & Affiliations
- Adjunct Associate Professor in the Department of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2016
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- Box 3305 Med Ctr, Durham, NC 27710
- Dept of Surgery, Durham, NC 27710
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mark.onaitis@duke.edu
(919) 684-6974
- Background
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Education, Training, & Certifications
- M.H.S., Duke University School of Medicine 2010
- M.D., Duke University 1997
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Previous Appointments & Affiliations
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1997 - 2017
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2016
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2011 - 2016
- Assistant Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2007 - 2011
- Research
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Selected Grants
- National Longitudinal Outcomes Following Surgical Therapy for Lung Cancer awarded by Society of Thoracic Surgeons 2014 - 2019
- Targeting Integrator Kinases in Lung Cancer Metastasis awarded by Free to Breathe 2015 - 2018
- Anti-CTGF Therapy for Squamous Cell Lung Cancer awarded by National Institutes of Health 2016 - 2017
- K-RAS mutant lung adenocarcinoma treatment awarded by AATS Graham Foundation 2014 - 2016
- Novel druggable pathway required for lung cancer progression and metastasis awarded by Uniting Against Lung Cancer 2014 - 2016
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Burt, B. M., and M. Onaitis. “Robotic Ivor-Lewis esophagectomy in 15 steps.” Jtcvs Techniques, January 1, 2023. https://doi.org/10.1016/j.xjtc.2023.03.007.Full Text
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Onaitis, M. “Discussion.” Journal of Thoracic and Cardiovascular Surgery, January 1, 2023. https://doi.org/10.1016/j.jtcvs.2023.03.013.Full Text
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Onaitis, Mark. “Discussion.” J Thorac Cardiovasc Surg 165, no. 1 (January 2023): 349–50. https://doi.org/10.1016/j.jtcvs.2022.08.041.Full Text Link to Item
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Erwin, Philip A., Andy C. Lee, Usman Ahmad, Mara Antonoff, Andrew Arndt, Leah Backhus, Mark Berry, et al. “Consensus for Thoracoscopic Lower Lobectomy: Essential Components and Targets for Simulation.” Ann Thorac Surg 114, no. 5 (November 2022): 1895–1901. https://doi.org/10.1016/j.athoracsur.2021.09.033.Full Text Link to Item
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Wood, Douglas E., Ella A. Kazerooni, Denise Aberle, Abigail Berman, Lisa M. Brown, Georgie A. Eapen, David S. Ettinger, et al. “NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022.” J Natl Compr Canc Netw 20, no. 7 (July 2022): 754–64. https://doi.org/10.6004/jnccn.2022.0036.Full Text Link to Item
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Smith, Ryan J., Hongpan Zhang, Shengen Shawn Hu, Theodora Yung, Roshane Francis, Lilian Lee, Mark W. Onaitis, Peter B. Dirks, Chongzhi Zang, and Tae-Hee Kim. “Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions.” Nat Commun 13, no. 1 (May 26, 2022): 2965. https://doi.org/10.1038/s41467-022-30624-w.Full Text Link to Item
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Boys, Josh, and Mark Onaitis. “Commentary: You can't hit what you can't see: Esophageal adenocarcinoma with signet ring cells.” J Thorac Cardiovasc Surg 162, no. 5 (November 2021): 1415–16. https://doi.org/10.1016/j.jtcvs.2020.09.090.Full Text Link to Item
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Wilshire, Candice L., Sandra L. Blitz, Carson C. Fuller, Jens C. Rückert, Feng Li, Robert J. Cerfolio, Asem F. Ghanim, et al. “Minimally invasive thymectomy for myasthenia gravis favours left-sided approach and low severity class.” Eur J Cardiothorac Surg 60, no. 4 (October 22, 2021): 898–905. https://doi.org/10.1093/ejcts/ezab014.Full Text Link to Item
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Bazhenova, Lyudmila, James Urbanic, and Mark Onaitis. “Commentary: Epidermal growth factor receptor mutations in resectable lung cancer: What is the prognostic importance?” J Thorac Cardiovasc Surg 162, no. 3 (September 2021): 676–77. https://doi.org/10.1016/j.jtcvs.2020.06.109.Full Text Link to Item
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Horgan, Santiago, and Mark Onaitis. “Commentary: Minimally invasive esophagectomy: Steady progress.” J Thorac Cardiovasc Surg 162, no. 3 (September 2021): 707–8. https://doi.org/10.1016/j.jtcvs.2021.02.054.Full Text Link to Item
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Sienicki, Elise, and Mark Onaitis. “Commentary: New players in epidermal growth factor receptor tyrosine kinase inhibitor resistance.” J Thorac Cardiovasc Surg 162, no. 2 (August 2021): 474–75. https://doi.org/10.1016/j.jtcvs.2020.04.096.Full Text Link to Item
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Broderick, Ryan C., Arielle M. Lee, Rachel R. Blitzer, Beiqun Zhao, Jenny Lam, Joslin N. Cheverie, Bryan J. Sandler, et al. “It's not always too late: a case for minimally invasive salvage esophagectomy.” Surg Endosc 35, no. 8 (August 2021): 4700–4711. https://doi.org/10.1007/s00464-020-07937-2.Full Text Link to Item
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Bryan, Darren S., Mark K. Ferguson, Mara B. Antonoff, Leah M. Backhus, Thomas J. Birdas, Shanda H. Blackmon, Daniel J. Boffa, et al. “Consensus for Thoracoscopic Left Upper Lobectomy-Essential Components and Targets for Simulation.” Ann Thorac Surg 112, no. 2 (August 2021): 436–42. https://doi.org/10.1016/j.athoracsur.2020.06.152.Full Text Link to Item
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Brown, Lisa M., Dylan P. Thibault, Andrzej S. Kosinski, David T. Cooke, Mark W. Onaitis, Henning A. Gaissert, and Patrick S. Romano. “Readmission After Lobectomy for Lung Cancer: Not All Complications Contribute Equally.” Ann Surg 274, no. 1 (July 1, 2021): e70–79. https://doi.org/10.1097/SLA.0000000000003561.Full Text Link to Item
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Medbery, Rachel L., Felix G. Fernandez, Andrzej S. Kosinski, Betty C. Tong, Anthony P. Furnary, Liqi Feng, Mark Onaitis, et al. “Costs Associated With Lobectomy for Lung Cancer: An Analysis Merging STS and Medicare Data.” Ann Thorac Surg 111, no. 6 (June 2021): 1781–90. https://doi.org/10.1016/j.athoracsur.2020.08.073.Full Text Link to Item
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Cowper, Patricia A., Liqi Feng, Andrzej S. Kosinski, Betty C. Tong, Robert H. Habib, Joe B. Putnam, Mark W. Onaitis, et al. “Initial and Longitudinal Cost of Surgical Resection for Lung Cancer.” Ann Thorac Surg 111, no. 6 (June 2021): 1827–33. https://doi.org/10.1016/j.athoracsur.2020.07.048.Full Text Link to Item
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Boys, Josh, and Mark Onaitis. “Commentary: Predicting intrathoracic pathologic concordance in patients with metastatic nonseminomatous germ cell tumor is clearly unclear.” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 871–72. https://doi.org/10.1016/j.jtcvs.2020.11.132.Full Text Link to Item
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Onaitis, Mark. “Commentary: Survival after small cell lung cancer resection: Small opportunity?” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 773–74. https://doi.org/10.1016/j.jtcvs.2020.11.069.Full Text Link to Item
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Onaitis, Mark. “Commentary: Induction immunotherapy for esophageal cancer: A safe start.” J Thorac Cardiovasc Surg 161, no. 3 (March 2021): 844. https://doi.org/10.1016/j.jtcvs.2020.12.027.Full Text Link to Item
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Golts, Eugene, and Mark Onaitis. “Commentary: Ischemia reperfusion-Looking ahead.” J Thorac Cardiovasc Surg 161, no. 2 (February 2021): e124–25. https://doi.org/10.1016/j.jtcvs.2019.12.010.Full Text Link to Item
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Fetten, Katharina, and Mark Onaitis. “Commentary: Octogenarians and Esophageal Cancer, Are We Afraid to Treat, or Are We Missing Information?” Semin Thorac Cardiovasc Surg 33, no. 3 (2021): 893–94. https://doi.org/10.1053/j.semtcvs.2020.10.037.Full Text Link to Item
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Patel, Sandip Pravin, and Mark Onaitis. “Commentary: Induction Immunotherapy: Intriguing Initiative for Investigation.” Semin Thorac Cardiovasc Surg 33, no. 3 (2021): 858–59. https://doi.org/10.1053/j.semtcvs.2021.02.013.Full Text Link to Item
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Onaitis, Mark W., Anthony P. Furnary, Andrzej S. Kosinski, Liqi Feng, Daniel Boffa, Betty C. Tong, Patricia Cowper, et al. “Equivalent Survival Between Lobectomy and Segmentectomy for Clinical Stage IA Lung Cancer.” Ann Thorac Surg 110, no. 6 (December 2020): 1882–91. https://doi.org/10.1016/j.athoracsur.2020.01.020.Full Text Link to Item
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Onaitis, Mark. “Discussion.” J Thorac Cardiovasc Surg 160, no. 4 (October 2020): 1073. https://doi.org/10.1016/j.jtcvs.2019.12.116.Full Text Link to Item
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Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.Full Text Link to Item
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Boys, Joshua, and Mark Onaitis. “Commentary: Breaking down non-small cell lung cancer tumor microenvironment heterogeneity and predicting response to immune checkpoint inhibitors.” J Thorac Cardiovasc Surg 159, no. 4 (April 2020): 1612–13. https://doi.org/10.1016/j.jtcvs.2019.11.097.Full Text Link to Item
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Garman, Katherine S., Teminioluwa A. Ajayi, Harold J. Boutte, Shih-Ting Chiu, Richard J. von Furstenberg, Benjamin R. Lloyd, Cecelia Zhang, Mark W. Onaitis, Shein-Chung Chow, and Shannon J. McCall. “Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma.” Plos One 15, no. 7 (2020): e0235906. https://doi.org/10.1371/journal.pone.0235906.Full Text Link to Item
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Galant-Swafford, Jessica, Matthew Light, Mark W. Onaitis, Stephen A. Rawlings, Joshua Fierer, and Judd W. Landsberg. “A 37-Year-Old Man With Pleuritic Chest Pain.” Chest 156, no. 1 (July 2019): e15–21. https://doi.org/10.1016/j.chest.2019.02.002.Full Text Link to Item
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Huang, L., Y. Shen, and M. Onaitis. “Comparative study of anatomic lung resection by robotic vs. Video-assisted thoracoscopic surgery.” Journal of Thoracic Disease 11, no. 4 (April 1, 2019): 1243–50. https://doi.org/10.21037/jtd.2019.03.104.Full Text
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Fernandez, Felix G., Andrzej S. Kosinski, Betty C. Tong, Anthony P. Furnary, Liqi Feng, Mark Onaitis, Daniel Boffa, et al. “Lack of correlation between short- and long-term performance after lung cancer surgery.” J Thorac Cardiovasc Surg 157, no. 4 (April 2019): 1633-1643.e3. https://doi.org/10.1016/j.jtcvs.2018.09.141.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Shivani A. Shah, Belle K. Lin, Keith W. VanDusen, Derek Y. Chan, Wendy D. Tan, David N. Ranney, Morgan L. Cox, Thomas A. D’Amico, and Mark F. Berry. “Right-Sided Versus Left-Sided Pneumonectomy After Induction Therapy for Non-Small Cell Lung Cancer.” Ann Thorac Surg 107, no. 4 (April 2019): 1074–81. https://doi.org/10.1016/j.athoracsur.2018.10.009.Full Text Link to Item
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Wolfe, Gil I., Henry J. Kaminski, Inmaculada B. Aban, Greg Minisman, Hui-Chien Kuo, Alexander Marx, Philipp Ströbel, et al. “Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.” Lancet Neurol 18, no. 3 (March 2019): 259–68. https://doi.org/10.1016/S1474-4422(18)30392-2.Full Text Link to Item
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Tong, Betty C., Sunghee Kim, Andrzej Kosinski, Mark W. Onaitis, Daniel J. Boffa, Robert H. Habib, Joe B. Putnam, et al. “Penetration, Completeness, and Representativeness of The Society of Thoracic Surgeons General Thoracic Surgery Database for Lobectomy.” Ann Thorac Surg 107, no. 3 (March 2019): 897–902. https://doi.org/10.1016/j.athoracsur.2018.07.059.Full Text Link to Item
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Boffa, Daniel J., Andrzej S. Kosinski, Anthony P. Furnary, Sunghee Kim, Mark W. Onaitis, Betty C. Tong, Patricia A. Cowper, et al. “Minimally Invasive Lung Cancer Surgery Performed by Thoracic Surgeons as Effective as Thoracotomy.” J Clin Oncol 36, no. 23 (August 10, 2018): 2378–85. https://doi.org/10.1200/JCO.2018.77.8977.Full Text Link to Item
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Iglesias-Bartolome, Ramiro, Akihiko Uchiyama, Alfredo A. Molinolo, Loreto Abusleme, Stephen R. Brooks, Juan Luis Callejas-Valera, Dean Edwards, et al. “Transcriptional signature primes human oral mucosa for rapid wound healing.” Sci Transl Med 10, no. 451 (July 25, 2018). https://doi.org/10.1126/scitranslmed.aap8798.Full Text Link to Item
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Upham, Trevor C., and Mark W. Onaitis. “Video-assisted thoracoscopic surgery versus robot-assisted thoracoscopic surgery versus thoracotomy for early-stage lung cancer.” J Thorac Cardiovasc Surg 156, no. 1 (July 2018): 365–68. https://doi.org/10.1016/j.jtcvs.2018.02.064.Full Text Link to Item
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Fernandez, Felix G., Andrzej S. Kosinski, Anthony P. Furnary, Mark Onaitis, Sunghee Kim, Robert H. Habib, Betty C. Tong, et al. “Differential effects of operative complications on survival after surgery for primary lung cancer.” J Thorac Cardiovasc Surg 155, no. 3 (March 2018): 1254-1264.e1. https://doi.org/10.1016/j.jtcvs.2017.09.149.Full Text Link to Item
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Cheng, Xinghua, Mark W. Onaitis, Thomas A. D’amico, and Haiquan Chen. “Minimally Invasive Thoracic Surgery 3.0: Lessons Learned From the History of Lung Cancer Surgery.” Ann Surg 267, no. 1 (January 2018): 37–38. https://doi.org/10.1097/SLA.0000000000002405.Full Text Link to Item
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Tirrell, T., and M. Onaitis. “Lymph node assessment and survival: We still have work to do.” Journal of Thoracic Disease 10, no. 1 (January 1, 2018): 15–16. https://doi.org/10.21037/jtd.2017.12.112.Full Text
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Onaitis, Mark W., Anthony P. Furnary, Andrzej S. Kosinski, Sunghee Kim, Daniel Boffa, Betty C. Tong, Patricia Cowper, et al. “Prediction of Long-Term Survival After Lung Cancer Surgery for Elderly Patients in The Society of Thoracic Surgeons General Thoracic Surgery Database.” Ann Thorac Surg 105, no. 1 (January 2018): 309–16. https://doi.org/10.1016/j.athoracsur.2017.06.071.Full Text Link to Item
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Boyer, Matthew J., Christina D. Williams, David H. Harpole, Mark W. Onaitis, Michael J. Kelley, and Joseph K. Salama. “Improved Survival of Stage I Non-Small Cell Lung Cancer: A VA Central Cancer Registry Analysis.” J Thorac Oncol 12, no. 12 (December 2017): 1814–23. https://doi.org/10.1016/j.jtho.2017.09.1952.Full Text Link to Item
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Gaissert, Henning A., Felix G. Fernandez, Traves Crabtree, William R. Burfeind, Mark S. Allen, Mark I. Block, Paul H. Schipper, et al. “The Society of Thoracic Surgeons General Thoracic Surgery Database: 2017 Update on Research.” Ann Thorac Surg 104, no. 5 (November 2017): 1450–55. https://doi.org/10.1016/j.athoracsur.2017.08.060.Full Text Link to Item
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Asselin-Labat, Marie-Liesse, Rishi Rampersad, Xia Xu, Matthew E. Ritchie, Jacob Michalski, Lingling Huang, and Mark W. Onaitis. “High-LET Radiation Increases Tumor Progression in a K-Ras-Driven Model of Lung Adenocarcinoma.” Radiat Res 188, no. 5 (November 2017): 562–70. https://doi.org/10.1667/RR14794.1.Full Text Link to Item
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Karhausen, Jörn A., Alan M. Smeltz, Igor Akushevich, Mary Cooter, Mihai V. Podgoreanu, Mark Stafford-Smith, Susan M. Martinelli, Manuel L. Fontes, and Miklos D. Kertai. “Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery.” Anesth Analg 125, no. 4 (October 2017): 1129–39. https://doi.org/10.1213/ANE.0000000000002187.Full Text Open Access Copy Link to Item
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Cerfolio, Robert, Brian E. Louie, Alexander S. Farivar, Mark Onaitis, and Bernard J. Park. “Consensus statement on definitions and nomenclature for robotic thoracic surgery.” J Thorac Cardiovasc Surg 154, no. 3 (September 2017): 1065–69. https://doi.org/10.1016/j.jtcvs.2017.02.081.Full Text Link to Item
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Roberts, Sheridan L., Xin-Peng Dun, Robin D. S. Doddrell, Thomas Mindos, Louisa K. Drake, Mark W. Onaitis, Francesca Florio, et al. “Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.” Development 144, no. 17 (September 1, 2017): 3114–25. https://doi.org/10.1242/dev.150656.Full Text Link to Item
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Boffa, Daniel, Felix G. Fernandez, Sunghee Kim, Andrzej Kosinski, Mark W. Onaitis, Patricia Cowper, Jeffrey P. Jacobs, Cameron D. Wright, Joe B. Putnam, and Anthony P. Furnary. “Surgically Managed Clinical Stage IIIA-Clinical N2 Lung Cancer in The Society of Thoracic Surgeons Database.” Ann Thorac Surg 104, no. 2 (August 2017): 395–403. https://doi.org/10.1016/j.athoracsur.2017.02.031.Full Text Link to Item
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Gu, Jing Jin, Clay Rouse, Xia Xu, Jun Wang, Mark W. Onaitis, and Ann Marie Pendergast. “Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis.” Jci Insight 1, no. 21 (December 22, 2016): e89647. https://doi.org/10.1172/jci.insight.89647.Full Text Link to Item
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Gulack, Brian C., Chi-Fu Jeffrey Yang, Paul J. Speicher, Babatunde A. Yerokun, Betty C. Tong, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, Matthew G. Hartwig, and Mark F. Berry. “A Risk Score to Assist Selecting Lobectomy Versus Sublobar Resection for Early Stage Non-Small Cell Lung Cancer.” Ann Thorac Surg 102, no. 6 (December 2016): 1814–20. https://doi.org/10.1016/j.athoracsur.2016.06.032.Full Text Link to Item
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Gaissert, Henning A., Felix G. Fernandez, Mark S. Allen, William R. Burfeind, Mark I. Block, James M. Donahue, John D. Mitchell, et al. “The Society of Thoracic Surgeons General Thoracic Surgery Database: 2016 Update on Research.” Ann Thorac Surg 102, no. 5 (November 2016): 1444–51. https://doi.org/10.1016/j.athoracsur.2016.09.014.Full Text Link to Item
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Onaitis, Mark, and Bernard Park. “Teaching robotic surgery: Making progress.” J Thorac Cardiovasc Surg 152, no. 4 (October 2016): 950–51. https://doi.org/10.1016/j.jtcvs.2016.07.039.Full Text Link to Item
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Boyer, Matthew J., Lin Gu, Xiaofei Wang, Chris R. Kelsey, David S. Yoo, Mark W. Onaitis, Frank R. Dunphy, Jeffrey Crawford, Neal E. Ready, and Joseph K. Salama. “Toxicity of definitive and post-operative radiation following ipilimumab in non-small cell lung cancer.” Lung Cancer 98 (August 2016): 76–78. https://doi.org/10.1016/j.lungcan.2016.05.014.Full Text Link to Item
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Yerokun, Babatunde A., Zhifei Sun, Chi-Fu Jeffrey Yang, Brian C. Gulack, Paul J. Speicher, Mohamed A. Adam, Thomas A. D’Amico, et al. “Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis.” Ann Thorac Surg 102, no. 2 (August 2016): 416–23. https://doi.org/10.1016/j.athoracsur.2016.02.078.Full Text Link to Item
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Onaitis, Mark W., and Joseph Salama. “Surgery versus stereotactic body radiation therapy for operable stage I non-small cell lung cancer: Can we achieve equipoise?” J Thorac Cardiovasc Surg 152, no. 1 (July 2016): 1–2. https://doi.org/10.1016/j.jtcvs.2016.04.016.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Robert Ryan Meyerhoff, Nicholas Ryan Mayne, Terry Singhapricha, Christopher B. Toomey, Paul J. Speicher, Matthew G. Hartwig, et al. “Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1615–23. https://doi.org/10.1093/ejcts/ezv428.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Syed M. Adil, Kevin L. Anderson, Robert Ryan Meyerhoff, Ryan S. Turley, Matthew G. Hartwig, David H. Harpole, et al. “Impact of patient selection and treatment strategies on outcomes after lobectomy for biopsy-proven stage IIIA pN2 non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1607–13. https://doi.org/10.1093/ejcts/ezv431.Full Text Link to Item
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Fernandez, Felix G., Anthony P. Furnary, Andrzej S. Kosinski, Mark W. Onaitis, Sunghee Kim, Daniel Boffa, Patricia Cowper, Jeffrey P. Jacobs, Cameron D. Wright, and Joe B. Putnam. “Longitudinal Follow-up of Lung Cancer Resection From the Society of Thoracic Surgeons General Thoracic Surgery Database in Patients 65 Years and Older.” Ann Thorac Surg 101, no. 6 (June 2016): 2067–76. https://doi.org/10.1016/j.athoracsur.2016.03.034.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Xiaofei Wang, Matthew G. Hartwig, Mark W. Onaitis, et al. “Role of Adjuvant Therapy in a Population-Based Cohort of Patients With Early-Stage Small-Cell Lung Cancer.” J Clin Oncol 34, no. 10 (April 1, 2016): 1057–64. https://doi.org/10.1200/JCO.2015.63.8171.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Zhifei Sun, Paul J. Speicher, Shakir M. Saud, Brian C. Gulack, Matthew G. Hartwig, David H. Harpole, et al. “Use and Outcomes of Minimally Invasive Lobectomy for Stage I Non-Small Cell Lung Cancer in the National Cancer Data Base.” Ann Thorac Surg 101, no. 3 (March 2016): 1037–42. https://doi.org/10.1016/j.athoracsur.2015.11.018.Full Text Link to Item
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Kang, Xiaozheng, Hongliang Liu, Mark W. Onaitis, Zhensheng Liu, Kouros Owzar, Younghun Han, Li Su, et al. “Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls.” Carcinogenesis 37, no. 3 (March 2016): 280–89. https://doi.org/10.1093/carcin/bgw014.Full Text Link to Item
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Oprea, Adriana D., Manuel L. Fontes, Mark W. Onaitis, and Miklos D. Kertai. “Comparison Between the 2007 and 2014 American College of Cardiology/American Heart Association Guidelines on Perioperative Evaluation for Noncardiac Surgery.” J Cardiothorac Vasc Anesth 29, no. 6 (December 2015): 1639–50. https://doi.org/10.1053/j.jvca.2015.04.021.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Brian C. Gulack, Lin Gu, Paul J. Speicher, Xiaofei Wang, David H. Harpole, Mark W. Onaitis, Thomas A. D’Amico, Mark F. Berry, and Matthew G. Hartwig. “Adding radiation to induction chemotherapy does not improve survival of patients with operable clinical N2 non-small cell lung cancer.” J Thorac Cardiovasc Surg 150, no. 6 (December 2015): 1484–92. https://doi.org/10.1016/j.jtcvs.2015.06.062.Full Text Link to Item
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Yang, Chi-Fu J., Derek Y. Chan, Brian C. Gulack, Paul J. Speicher, Mark W. Onaitis, Betty C. Tong, Thomas A. D’Amico, David Harpole, Mark F. Berry, and Matthew G. Hartwig. “Wedge Resection vs Segmentectomy for Patients with T1A N0 Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S242–S242.Link to Item
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Yang, Chi-Fu J., Derek Y. Chan, Brian C. Gulack, Paul J. Speicher, Matthew G. Hartwig, Mark F. Berry, Betty C. Tong, Mark W. Onaitis, Thomas A. D’Amico, and David Harpole. “Survival after Surgery for pN1 and pN2 Small Cell Lung Cancer: A Comparison with Surgical Treatment of Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S399–400.Link to Item
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Yang, Chi-Fu J., Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Mark W. Onaitis, Matthew G. Hartwig, Betty C. Tong, Mark F. Berry, Thomas A. D’Amico, and David Harpole. “Long-Term Survival after Surgery for Pathologic N1 and N2 Small Cell Lung Cancer: A Comparison with Nonoperative Management.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S193–94.Link to Item
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Yang, Chi-Fu J., Syed M. Adil, Robert R. Meyerhoff, Kevin L. Anderson, Sameer A. Hirji, David Harpole, Betty C. Tong, et al. “Impact of Radiation on Recurrence Patterns and Survival for Patients Undergoing Lobectomy for Stage IIIA-pN2 Non-Small Cell Lung Cancer.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S573–S573.Link to Item
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Tang, Paul, Mark Onaitis, Jeffrey G. Gaca, Carmelo A. Milano, Mark Stafford-Smith, and Donald Glower. “Right Minithoracotomy Versus Median Sternotomy for Mitral Valve Surgery: A Propensity Matched Study.” Ann Thorac Surg 100, no. 2 (August 2015): 575–81. https://doi.org/10.1016/j.athoracsur.2015.04.027.Full Text Open Access Copy Link to Item
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Berry, Mark F., Chi-Fu Jeffrey Yang, Matthew G. Hartwig, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Impact of Pulmonary Function Measurements on Long-Term Survival After Lobectomy for Stage I Non-Small Cell Lung Cancer.” Ann Thorac Surg 100, no. 1 (July 2015): 271–76. https://doi.org/10.1016/j.athoracsur.2015.02.076.Full Text Link to Item
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Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Outcomes after treatment of 17,378 patients with locally advanced (T3N0-2) non-small-cell lung cancer.” Eur J Cardiothorac Surg 47, no. 4 (April 2015): 636–41. https://doi.org/10.1093/ejcts/ezu270.Full Text Link to Item
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Xiao, Lin, Dae Joong Kim, Clayton L. Davis, James V. McCann, James M. Dunleavey, Alissa K. Vanderlinden, Nuo Xu, et al. “Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition.” Cancer Res 75, no. 7 (April 1, 2015): 1244–54. https://doi.org/10.1158/0008-5472.CAN-14-1616.Full Text Link to Item
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Coleman, Brooke K., Lesley H. Curtis, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Adjuvant chemotherapy after resection of N1 non-small cell lung cancer: differential impact of new evidence on physician and patient decisions.” J Thorac Dis 7, no. 3 (March 2015): 243–51. https://doi.org/10.3978/j.issn.2072-1439.2015.01.42.Full Text Link to Item
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Hanna, Jennifer M., Loretta Erhunmwunsee, Mark Berry, Thomas D’Amico, and Mark Onaitis. “The prognostic importance of the number of dissected lymph nodes after induction chemoradiotherapy for esophageal cancer.” Ann Thorac Surg 99, no. 1 (January 2015): 265–69. https://doi.org/10.1016/j.athoracsur.2014.08.073.Full Text Link to Item
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Kara, Hasan Volkan, Mohan K. Mallipeddi, Jeffrey Javidfar, and Mark W. Onaitis. “Benign emptying of the postpneumonectomy space.” Lung India 32, no. 6 (2015): 614–15. https://doi.org/10.4103/0970-2113.168136.Full Text Link to Item
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Linden, Philip A., Thomas A. D’Amico, Yaron Perry, Paramita Saha-Chaudhuri, Shubin Sheng, Sunghee Kim, and Mark Onaitis. “Quantifying the safety benefits of wedge resection: a society of thoracic surgery database propensity-matched analysis.” Ann Thorac Surg 98, no. 5 (November 2014): 1705–11. https://doi.org/10.1016/j.athoracsur.2014.06.017.Full Text Link to Item
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Xu, Xia, Lingling Huang, Christopher Futtner, Brian Schwab, Rishi R. Rampersad, Yun Lu, Thomas A. Sporn, Brigid L. M. Hogan, and Mark W. Onaitis. “The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.” Genes Dev 28, no. 17 (September 1, 2014): 1929–39. https://doi.org/10.1101/gad.243717.114.Full Text Link to Item
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Speicher, Paul J., Asvin M. Ganapathi, Brian R. Englum, Matthew G. Hartwig, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Induction therapy does not improve survival for clinical stage T2N0 esophageal cancer.” J Thorac Oncol 9, no. 8 (August 2014): 1195–1201. https://doi.org/10.1097/JTO.0000000000000228.Full Text Link to Item
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Burt, Bryan M., Andrzej S. Kosinski, Joseph B. Shrager, Mark W. Onaitis, and Tracey Weigel. “Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal.” J Thorac Cardiovasc Surg 148, no. 1 (July 2014): 19–28. https://doi.org/10.1016/j.jtcvs.2014.03.007.Full Text Link to Item
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Hanna, Jennifer M., and Mark W. Onaitis. “Robotic benign esophageal procedures.” Thorac Surg Clin 24, no. 2 (May 2014): 223–vii. https://doi.org/10.1016/j.thorsurg.2014.02.004.Full Text Link to Item
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Huang, Lingling, and Mark Onaitis. “Minimally invasive and robotic Ivor Lewis esophagectomy.” J Thorac Dis 6 Suppl 3, no. Suppl 3 (May 2014): S314–21. https://doi.org/10.3978/j.issn.2072-1439.2014.04.32.Full Text Link to Item
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Huang, Lingling, Vonn Walter, D Neil Hayes, and Mark Onaitis. “Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.” Clin Cancer Res 20, no. 6 (March 15, 2014): 1566–75. https://doi.org/10.1158/1078-0432.CCR-13-2195.Full Text Link to Item
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Speicher, Paul J., Asvin M. Ganapathi, Brian R. Englum, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Survival in the elderly after pneumonectomy for early-stage non-small cell lung cancer: a comparison with nonoperative management.” J Am Coll Surg 218, no. 3 (March 2014): 439–49. https://doi.org/10.1016/j.jamcollsurg.2013.12.005.Full Text Link to Item
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Liu, Kuancan, Ming Jiang, Yun Lu, Hao Chen, Jun Sun, Shaoping Wu, Wei-Yao Ku, et al. “Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells.” Cell Stem Cell 12, no. 3 (March 7, 2013): 304–15. https://doi.org/10.1016/j.stem.2013.01.007.Full Text Link to Item
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Villamizar, Nestor R., Marcus Darrabie, Jennifer Hanna, Mark W. Onaitis, Betty C. Tong, Thomas A. D’Amico, and Mark F. Berry. “Impact of T status and N status on perioperative outcomes after thoracoscopic lobectomy for lung cancer.” J Thorac Cardiovasc Surg 145, no. 2 (February 2013): 514–20. https://doi.org/10.1016/j.jtcvs.2012.10.039.Full Text Link to Item
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Hanna, Jennifer M., and Mark W. Onaitis. “Cell of origin of lung cancer.” J Carcinog 12 (2013): 6. https://doi.org/10.4103/1477-3163.109033.Full Text Link to Item
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Tang, Paul, Mark Onaitis, Bhargavi Desai, Jeffrey G. Gaca, Carmelo A. Milano, Mark Stafford-Smith, and Donald D. Glower. “Minithoracotomy versus sternotomy for mitral surgery in patients with chronic renal impairment: a propensity-matched study.” Innovations (Phila) 8, no. 5 (2013): 325–31. https://doi.org/10.1097/IMI.0000000000000020.Full Text Link to Item
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Hanna, J. M., and M. W. Onaitis. “Technique of Video-Assisted Thoracoscopic Chest Wall Resection.” Operative Techniques in Thoracic and Cardiovascular Surgery 17, no. 4 (December 1, 2012): 280–91. https://doi.org/10.1053/j.optechstcvs.2012.11.002.Full Text
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Ceppa, DuyKhanh P., Andrzej S. Kosinski, Mark F. Berry, Betty C. Tong, David H. Harpole, John D. Mitchell, Thomas A. D’Amico, and Mark W. Onaitis. “Thoracoscopic lobectomy has increasing benefit in patients with poor pulmonary function: a Society of Thoracic Surgeons Database analysis.” Ann Surg 256, no. 3 (September 2012): 487–93. https://doi.org/10.1097/SLA.0b013e318265819c.Full Text Link to Item
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Boffa, Daniel J., Andrzej S. Kosinski, Subroto Paul, John D. Mitchell, and Mark Onaitis. “Lymph node evaluation by open or video-assisted approaches in 11,500 anatomic lung cancer resections.” Ann Thorac Surg 94, no. 2 (August 2012): 347–53. https://doi.org/10.1016/j.athoracsur.2012.04.059.Full Text Link to Item
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Boffa, Daniel J., Sidharta Gangadharan, Michael Kent, Faraz Kerendi, Mark Onaitis, Edward Verrier, and Eric Roselli. “Self-perceived video-assisted thoracic surgery lobectomy proficiency by recent graduates of North American thoracic residencies.” Interact Cardiovasc Thorac Surg 14, no. 6 (June 2012): 797–800. https://doi.org/10.1093/icvts/ivr098.Full Text Link to Item
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Berry, Mark F., Mark W. Onaitis, Betty C. Tong, Stafford S. Balderson, David H. Harpole, and Thomas A. D’Amico. “Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection.” Eur J Cardiothorac Surg 41, no. 4 (April 2012): 888–92. https://doi.org/10.1093/ejcts/ezr150.Full Text Link to Item
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Shah, Asad A., Michael E. Barfield, Chris R. Kelsey, Mark W. Onaitis, Betty Tong, David Harpole, Thomas A. D’Amico, and Mark F. Berry. “Outcomes after surgical management of synchronous bilateral primary lung cancers.” Ann Thorac Surg 93, no. 4 (April 2012): 1055–60. https://doi.org/10.1016/j.athoracsur.2011.12.070.Full Text Link to Item
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Xu, Xia, Jason R. Rock, Yun Lu, Christopher Futtner, Brian Schwab, Justin Guinney, Brigid L. M. Hogan, and Mark W. Onaitis. “Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.” Proc Natl Acad Sci U S A 109, no. 13 (March 27, 2012): 4910–15. https://doi.org/10.1073/pnas.1112499109.Full Text Link to Item
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Ceppa, Duykhanh P., Ian J. Welsby, Tracy Y. Wang, Mark W. Onaitis, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark F. Berry. “Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection.” Ann Thorac Surg 92, no. 6 (December 2011): 1971–76. https://doi.org/10.1016/j.athoracsur.2011.07.052.Full Text Link to Item
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Atkins, B Zane, Mark W. Onaitis, Kelley A. Hutcheson, Keith Kaye, Rebecca P. Petersen, and Walter G. Wolfe. “Does method of sternal repair influence long-term outcome of postoperative mediastinitis?” Am J Surg 202, no. 5 (November 2011): 565–67. https://doi.org/10.1016/j.amjsurg.2011.06.013.Full Text Link to Item
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Higgins, Kristin A., Junzo P. Chino, Neal Ready, Mark W. Onaitis, Mark F. Berry, Thomas A. D’Amico, and Chris R. Kelsey. “Persistent N2 disease after neoadjuvant chemotherapy for non-small-cell lung cancer.” J Thorac Cardiovasc Surg 142, no. 5 (November 2011): 1175–79. https://doi.org/10.1016/j.jtcvs.2011.07.059.Full Text Link to Item
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Meltzer, Eric B., William T. Barry, Thomas A. D’Amico, Robert D. Davis, Shu S. Lin, Mark W. Onaitis, Lake D. Morrison, Thomas A. Sporn, Mark P. Steele, and Paul W. Noble. “Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principle.” Bmc Med Genomics 4 (October 5, 2011): 70. https://doi.org/10.1186/1755-8794-4-70.Full Text Link to Item
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Hartwig, Matthew G., Deverick J. Anderson, Mark W. Onaitis, Shekur Reddy, Laurie D. Snyder, Shu S. Lin, and R Duane Davis. “Fundoplication after lung transplantation prevents the allograft dysfunction associated with reflux.” Ann Thorac Surg 92, no. 2 (August 2011): 462–68. https://doi.org/10.1016/j.athoracsur.2011.04.035.Full Text Link to Item
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D’Amico, Thomas A., Betty C. Tong, Mark F. Berry, William R. Burfeind, and Mark W. Onaitis. “Incorporating research into thoracic surgery practice.” Thorac Surg Clin 21, no. 3 (August 2011): 369–77. https://doi.org/10.1016/j.thorsurg.2011.04.004.Full Text Link to Item
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D’Amico, Thomas A., Joyce Niland, Rizvan Mamet, Carrie Zornosa, Elisabeth U. Dexter, and Mark W. Onaitis. “Efficacy of mediastinal lymph node dissection during lobectomy for lung cancer by thoracoscopy and thoracotomy.” Ann Thorac Surg 92, no. 1 (July 2011): 226–31. https://doi.org/10.1016/j.athoracsur.2011.03.134.Full Text Link to Item
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Berry, Mark F., Mark W. Onaitis, Betty C. Tong, David H. Harpole, and Thomas A. D’Amico. “A model for morbidity after lung resection in octogenarians.” Eur J Cardiothorac Surg 39, no. 6 (June 2011): 989–94. https://doi.org/10.1016/j.ejcts.2010.09.038.Full Text Link to Item
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Swaminathan, Madhav, Alina Nicoara, Barbara G. Phillips-Bute, Nicolas Aeschlimann, Carmelo A. Milano, G Burkhard Mackensen, Mihai V. Podgoreanu, et al. “Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery.” Ann Thorac Surg 91, no. 6 (June 2011): 1844–50. https://doi.org/10.1016/j.athoracsur.2011.02.008.Full Text Link to Item
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Onaitis, Mark, Thomas A. D’Amico, Cheryl P. Clark, Justin Guinney, David H. Harpole, and Emma L. Rawlins. “A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.” Ann Thorac Surg 91, no. 4 (April 2011): 1046–50. https://doi.org/10.1016/j.athoracsur.2010.12.054.Full Text Link to Item
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Pepek, Joseph M., Junzo P. Chino, Lawrence B. Marks, Thomas A. D’amico, David S. Yoo, Mark W. Onaitis, Neal E. Ready, Jessica L. Hubbs, Jessamy Boyd, and Chris R. Kelsey. “How well does the new lung cancer staging system predict for local/regional recurrence after surgery?: A comparison of the TNM 6 and 7 systems.” J Thorac Oncol 6, no. 4 (April 2011): 757–61. https://doi.org/10.1097/JTO.0b013e31821038c0.Full Text Link to Item
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Walsh, Mark D., Anthony D. Bruno, Mark W. Onaitis, Detlev Erdmann, Walter G. Wolfe, Eric M. Toloza, and L Scott Levin. “The role of intrathoracic free flaps for chronic empyema.” Ann Thorac Surg 91, no. 3 (March 2011): 865–68. https://doi.org/10.1016/j.athoracsur.2010.10.019.Full Text Link to Item
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Hanna, Jennifer M., and Mark W. Onaitis. “Human lung stem cells: has the future arrived?” Semin Thorac Cardiovasc Surg 23, no. 4 (2011): 259–60. https://doi.org/10.1053/j.semtcvs.2011.10.009.Full Text Link to Item
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Berry, Mark F., B Zane Atkins, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia.” J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1266–71. https://doi.org/10.1016/j.jtcvs.2010.08.038.Full Text Link to Item
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Onaitis, Mark, Thomas D’Amico, Yue Zhao, Sean O’Brien, and David Harpole. “Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database.” Ann Thorac Surg 90, no. 2 (August 2010): 368–74. https://doi.org/10.1016/j.athoracsur.2010.03.100.Full Text Link to Item
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Lu, Yun, Christopher Futtner, Jason R. Rock, Xia Xu, Walter Whitworth, Brigid L. M. Hogan, and Mark W. Onaitis. “Evidence that SOX2 overexpression is oncogenic in the lung.” Plos One 5, no. 6 (June 10, 2010): e11022. https://doi.org/10.1371/journal.pone.0011022.Full Text Open Access Copy Link to Item
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Berry, Mark F., Nestor R. Villamizar-Ortiz, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Pulmonary function tests do not predict pulmonary complications after thoracoscopic lobectomy.” Ann Thorac Surg 89, no. 4 (April 2010): 1044–51. https://doi.org/10.1016/j.athoracsur.2009.12.065.Full Text Link to Item
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Paul, Subroto, Nasser K. Altorki, Shubin Sheng, Paul C. Lee, David H. Harpole, Mark W. Onaitis, Brendon M. Stiles, Jeffrey L. Port, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database.” J Thorac Cardiovasc Surg 139, no. 2 (February 2010): 366–78. https://doi.org/10.1016/j.jtcvs.2009.08.026.Full Text Link to Item
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Tong, Betty C., Jennifer Hanna, Eric M. Toloza, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, and William R. Burfeind. “Outcomes of video-assisted thoracoscopic decortication.” Ann Thorac Surg 89, no. 1 (January 2010): 220–25. https://doi.org/10.1016/j.athoracsur.2009.09.021.Full Text Link to Item
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Stevenson, Marvaretta, William Mostertz, Chaitanya Acharya, William Kim, Kelli Walters, William Barry, Kristin Higgins, et al. “Characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.” Clin Cancer Res 15, no. 24 (December 15, 2009): 7553–61. https://doi.org/10.1158/1078-0432.CCR-09-1939.Full Text Link to Item
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Berry, Mark F., Jennifer Hanna, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Risk factors for morbidity after lobectomy for lung cancer in elderly patients.” Ann Thorac Surg 88, no. 4 (October 2009): 1093–99. https://doi.org/10.1016/j.athoracsur.2009.06.012.Full Text Link to Item
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Rock, Jason R., Mark W. Onaitis, Emma L. Rawlins, Yun Lu, Cheryl P. Clark, Yan Xue, Scott H. Randell, and Brigid L. M. Hogan. “Basal cells as stem cells of the mouse trachea and human airway epithelium.” Proc Natl Acad Sci U S A 106, no. 31 (August 4, 2009): 12771–75. https://doi.org/10.1073/pnas.0906850106.Full Text Link to Item
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Villamizar, Nestor R., Marcus D. Darrabie, William R. Burfeind, Rebecca P. Petersen, Mark W. Onaitis, Eric Toloza, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy.” J Thorac Cardiovasc Surg 138, no. 2 (August 2009): 419–25. https://doi.org/10.1016/j.jtcvs.2009.04.026.Full Text Link to Item
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Erhunmwunsee, Loretta, and Mark W. Onaitis. “Smoking cessation and the success of lung cancer surgery.” Curr Oncol Rep 11, no. 4 (July 2009): 269–74. https://doi.org/10.1007/s11912-009-0038-y.Full Text Link to Item
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Onaitis, Mark W., Rebecca P. Petersen, John C. Haney, Leonard Saltz, Bernard Park, Raja Flores, Nabil Rizk, et al. “Prognostic factors for recurrence after pulmonary resection of colorectal cancer metastases.” Ann Thorac Surg 87, no. 6 (June 2009): 1684–88. https://doi.org/10.1016/j.athoracsur.2009.03.034.Full Text Link to Item
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Onaitis, M. W., J. Haney, R. Petersen, L. B. Saltz, R. M. Flores, N. Rizk, M. S. Bains, et al. “Factors influencing outcome after pulmonary resection for colorectal cancer (CRC) metastases in the current era.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 4024.Link to Item
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Onaitis, Mark W., Rebecca P. Petersen, Stafford S. Balderson, Eric Toloza, William R. Burfeind, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients.” Ann Surg 244, no. 3 (September 2006): 420–25. https://doi.org/10.1097/01.sla.0000234892.79056.63.Full Text Link to Item
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Onaitis, Mark, Kirk Ludwig, Anthony Perez-Tamayo, Marcia Gottfried, Linda Russell, Phillip Shadduck, Theodore Pappas, Hilliard F. Seigler, and Douglas S. Tyler. “The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions.” J Surg Oncol 94, no. 3 (September 1, 2006): 194–202. https://doi.org/10.1002/jso.20591.Full Text Link to Item
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Aloia, Thomas A., Elizabeth Grubbs, Mark Onaitis, Paul J. Mosca, Tsung-Yen Cheng, Hilliard Seigler, and Douglas S. Tyler. “Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response.” Arch Surg 140, no. 11 (November 2005): 1115–20. https://doi.org/10.1001/archsurg.140.11.1115.Full Text Link to Item
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Abdel-Wahab, Zeinab, Robin Cisco, Jens Dannull, Tomio Ueno, Omar Abdel-Wahab, Matthew F. Kalady, Mark W. Onaitis, Douglas S. Tyler, and Scott K. Pruitt. “Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses.” J Surg Res 124, no. 2 (April 2005): 264–73. https://doi.org/10.1016/j.jss.2004.10.002.Full Text Link to Item
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Safford, Shawn D., R Edward Coleman, Jon P. Gockerman, Joseph Moore, Jerome Feldman, Mark W. Onaitis, Douglas S. Tyler, and John A. Olson. “Iodine-131 metaiodobenzylguanidine treatment for metastatic carcinoid. Results in 98 patients.” Cancer 101, no. 9 (November 1, 2004): 1987–93. https://doi.org/10.1002/cncr.20592.Full Text Link to Item
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Kalady, Matthew F., Bercedis Peterson, John Baillie, Mark W. Onaitis, Omar I. Abdul-Wahab, James K. Howden, Paul S. Jowell, et al. “Pancreatic duct strictures: identifying risk of malignancy.” Ann Surg Oncol 11, no. 6 (June 2004): 581–88. https://doi.org/10.1245/ASO.2004.03.070.Full Text Link to Item
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Kalady, Matthew F., Mark W. Onaitis, Sirisha Emani, Zeinab Abdul-Wahab, Scott K. Pruitt, and Douglas S. Tyler. “Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific antipancreatic cancer T cells.” J Gastrointest Surg 8, no. 2 (February 2004): 175–81. https://doi.org/10.1016/j.gassur.2003.11.003.Full Text Link to Item
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Kalady, Matthew F., Mark W. Onaitis, Sirisha Emani, Zeinab Abdel-Wahab, Douglas S. Tyler, and Scott K. Pruitt. “Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity.” J Surg Res 116, no. 1 (January 2004): 24–31. https://doi.org/10.1016/j.jss.2003.09.003.Full Text Link to Item
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Onaitis, Mark W., Matthew F. Kalady, Sirisha Emani, Zeinab Abdel-Wahab, Douglas S. Tyler, and Scott K. Pruitt. “CD40 ligand is essential for generation of specific cytotoxic T cell responses in RNA-pulsed dendritic cell immunotherapy.” Surgery 134, no. 2 (August 2003): 300–305. https://doi.org/10.1067/msy.2003.240.Full Text Link to Item
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Onaitis, Mark, Michael Morse, Herbert Hurwitz, Peggy Cotton, Douglas Tyler, Pierre Clavien, and Bryan Clary. “Adjuvant hepatic arterial chemotherapy following metastasectomy in patients with isolated liver metastases.” Ann Surg 237, no. 6 (June 2003): 782–88. https://doi.org/10.1097/01.SLA.0000071561.76384.19.Full Text Link to Item
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Onaitis, M., R. White, and D. Tyler. “Carcinoid tumors of the gastrointestinal tract. A review and the Duke University institutional overview.” Minerva Chir 58, no. 1 (February 2003): 1–8.Link to Item
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Daniels, Larkin J., Stafford S. Balderson, Mark W. Onaitis, and Thomas A. D’Amico. “Thoracoscopic lobectomy: a safe and effective strategy for patients with stage I lung cancer.” Ann Thorac Surg 74, no. 3 (September 2002): 860–64. https://doi.org/10.1016/s0003-4975(02)03764-5.Full Text Link to Item
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Onaitis, Mark, Matthew F. Kalady, Scott Pruitt, and Douglas S. Tyler. “Dendritic cell gene therapy.” Surg Oncol Clin N Am 11, no. 3 (July 2002): 645–60. https://doi.org/10.1016/s1055-3207(02)00027-3.Full Text Link to Item
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Kalady, Matthew F., Mark W. Onaitis, Karen M. Padilla, Sirisha Emani, Douglas S. Tyler, and Scott K. Pruitt. “Enhanced dendritic cell antigen presentation in RNA-based immunotherapy.” J Surg Res 105, no. 1 (June 1, 2002): 17–24. https://doi.org/10.1006/jsre.2002.6435.Full Text Link to Item
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Kypson, Alan P., Mark W. Onaitis, Jerome M. Feldman, and Douglas S. Tyler. “Carcinoid and chylous ascites: an unusual association.” J Gastrointest Surg 6, no. 5 (2002): 781–83. https://doi.org/10.1016/s1091-255x(02)00014-8.Full Text Link to Item
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Onaitis, M. W., R. B. Noone, R. Fields, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival.” Ann Surg Oncol 8, no. 10 (December 2001): 801–6. https://doi.org/10.1007/s10434-001-0801-2.Full Text Link to Item
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Onaitis, M. W., P. M. Kirshbom, T. Z. Hayward, F. J. Quayle, J. M. Feldman, H. F. Seigler, and D. S. Tyler. “Gastrointestinal carcinoids: characterization by site of origin and hormone production.” Ann Surg 232, no. 4 (October 2000): 549–56. https://doi.org/10.1097/00000658-200010000-00010.Full Text Link to Item
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Kirshbom, P. M., A. R. Kherani, M. W. Onaitis, A. Hata, T. E. Kehoe, C. Feldman, J. M. Feldman, and D. S. Tyler. “Foregut carcinoids: a clinical and biochemical analysis.” Surgery 126, no. 6 (December 1999): 1105–10. https://doi.org/10.1067/msy.2099.101430.Full Text Link to Item
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Kirshbom, P. M., A. R. Kherani, M. W. Onaitis, J. M. Feldman, and D. S. Tyler. “Carcinoids of unknown origin: comparative analysis with foregut, midgut, and hindgut carcinoids.” Surgery 124, no. 6 (December 1998): 1063–70. https://doi.org/10.1067/msy.1998.93105.Full Text Link to Item
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Book Sections
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Onaitis, M. W., and T. A. D’amico. “Molecular biology of lung cancer.” In Cardiothoracic Surgery Review, 984–86, 2012.
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Harpole, D. H., and M. Onaitis. “Present concepts in the molecular biology of lung cancer.” In General Thoracic Surgery: Seventh Edition, 2–2:3577–91, 2011.
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Other Articles
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Onaitis, Mark W., and Thomas A. D’Amico. “Modern Management of Pulmonary Metastases.” Thorac Surg Clin, February 2016. https://doi.org/10.1016/j.thorsurg.2015.10.001.Full Text Link to Item
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Onaitis, Mark. “Invited Commentary.” Ann Thorac Surg, September 2015. https://doi.org/10.1016/j.athoracsur.2015.05.005.Full Text Link to Item
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Onaitis, Mark. “Invited commentary.” Ann Thorac Surg, November 2013. https://doi.org/10.1016/j.athoracsur.2013.06.001.Full Text Link to Item
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Stevenson, Marvaretta, William Mostertz, Chaitanya R. Acharya, William Kim, Kelli Walters, William Barry, Kristin Higgins, et al. “Retraction: characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.” Clin Cancer Res, March 15, 2012. https://doi.org/10.1158/1078-0432.CCR-12-0337.Full Text Link to Item
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Welsby, Ian J., Barbara Phillips-Bute, and Mark W. Onaitis. “Invited commentary.” Ann Thorac Surg, July 2010. https://doi.org/10.1016/j.athoracsur.2010.04.053.Full Text Link to Item
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Friesen, S. R., M. W. Onaitis, A. Frilling, K. A. Kelly, E. L. Kaplan, J. B. D. Mark, and H. T. Debas. “Gastrointestinal carcinoids: Characterization by site of origin and hormone production - Discussion.” Annals of Surgery. LIPPINCOTT WILLIAMS & WILKINS, October 1, 2000.Link to Item
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Conference Papers
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Iglesias-Bartolome, R., A. Uchiyama, R. Graf, A. A. Molinolo, L. Abusleme, S. R. Brooks, J. Callejas-Valera, et al. “1395 Unique transcriptional signature primes oral mucosa for rapid wound healing in humans.” In Journal of Investigative Dermatology, 138:S237–S237. Elsevier BV, 2018. https://doi.org/10.1016/j.jid.2018.03.1413.Full Text
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Yi, John, Jeffrey Melson Clarke, Patrick Healy, Xiaofei F. Wang, Debra Shoemaker, Mark W. Onaitis, Chelsae Dumbauld, et al. “Immune profiling of circulating T cells and TILs following neoadjuvant ipilimumab and chemotherapy in non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, 35:26–26. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.7_suppl.26.Full Text
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Yang, Chi-Fu Jeffrey, Derek Y. Chan, Babatunde Yerokun, Xiaofei F. Wang, Betty Caroline Tong, Thomas A. D’Amico, Mark W. Onaitis, Matthew G. Hartwig, Mark F. Berry, and David Harpole. “Surgery versus optimal medical management of early-stage small cell lung cancer.” In Journal of Clinical Oncology, 34:8511–8511. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.8511.Full Text
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Xu, Xia, Rishi Rampersad, Brigid L. M. Hogan, and Mark W. Onaitis. “Mechanism of Notch and Sox2 in Kras driven lung adenocarcinoma in type II cells∗.” In Journal of Thoracic Oncology, 11:S54–S54. Elsevier BV, 2016. https://doi.org/10.1016/j.jtho.2015.12.090.Full Text
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Mallipeddi, Mohan K., Walid R. Eltaraboulsi, Adam R. Shoffner, Ibtehaj A. Naqvi, Thomas A. D’Amico, Mark W. Onaitis, and Mark F. Berry. “When should surgeons begin surveillance with CT scans after lobectomy for stage 1A non-small cell lung cancer?” In Journal of Clinical Oncology, 32:7549–7549. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.7549.Full Text
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Speicher, Paul J., Brian R. Englum, Asvin M. Ganapathi, Mark W. Onaitis, Thomas A. D’Amico, and Mark F. Berry. “Association of adjuvant chemotherapy with improved survival after esophagectomy without induction therapy for node-positive adenocarinoma.” In Journal of Clinical Oncology, 32:4077–4077. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.4077.Full Text
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Erhunmwunsee, L., B. R. Englum, T. A. D’Amico, M. W. Onaitis, and M. F. Berry. “Impact of Pre-treatment Imaging on Survival of Esophagectomy after Induction Therapy for Esophageal Cancer: Who Should be Given the Benefit of Doubt?” In Annals of Surgical Oncology, 21:S151–S151. SPRINGER, 2014.Link to Item
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Mallipeddi, M. K., W. R. Eltaraboulsi, A. R. Shoffner, I. A. Naqvi, T. A. D’Amico, M. W. Onaitis, and M. F. Berry. “The Impact of Surveillance after Lobectomy for Stage IA Non-small Cell Lung Cancer.” In Annals of Surgical Oncology, 21:S153–54. SPRINGER, 2014.Link to Item
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Higgins, Kristin A., Neal E. Ready, Thomas A. D’amico, Mark W. Onaitis, Jeffrey Crawford, Robert Clough, Mark F. Berry, et al. “PERSISTENT N2 DISEASE AFTER NEOADJUVANT CHEMOTHERAPY-NOW WHAT?” In Journal of Thoracic Oncology, 6:S1572–S1572. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Onaitis, Mark W. “CASE PRESENTATION: SMALL T1 SUBPLEURAL LUNG LESION IN THE RIGHT UPPER LOBE, INCIDENTALLY FOUND.” In Journal of Thoracic Oncology, 6:S155–S155. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Pepek, J. M., J. P. Chino, M. W. Onaitis, L. B. Marks, N. Ready, J. Crawford, T. A. D’Amico, J. L. Hubbs, and C. R. Kelsey. “Does the revised TNM staging system for lung cancer better estimate actuarial rates of local/regional recurrence after surgery?” In Journal of Clinical Oncology, 28:7072–7072. American Society of Clinical Oncology (ASCO), 2010. https://doi.org/10.1200/jco.2010.28.15_suppl.7072.Full Text
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Rock, Jason R., Emma L. Rawlins, Mark W. Onaitis, and Brigid L. Hogan. “Basal cells as stem cells of the mouse trachea and human conducting airways.” In Developmental Biology, 331:503–503. Elsevier BV, 2009. https://doi.org/10.1016/j.ydbio.2009.05.438.Full Text
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Erhunmwunsee, Loretta, Yun Lu, Xiaoyan Luo, David H. Harpole, Brigid L. M. Hogan, and Mark W. Onaitis. “Basal cells in lung cancer.” In Journal of the American College of Surgeons, 207:S30–S30. Ovid Technologies (Wolters Kluwer Health), 2008. https://doi.org/10.1016/j.jamcollsurg.2008.06.053.Full Text
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Onaitis, M. W., J. Haney, R. Petersen, L. B. Saltz, R. M. Flores, N. Rizk, M. S. Bains, et al. “Factors influencing outcome after pulmonary resection for colorectal cancer (CRC) metastases in the current era.” In Journal of Clinical Oncology, 26:4024–4024. American Society of Clinical Oncology (ASCO), 2008. https://doi.org/10.1200/jco.2008.26.15_suppl.4024.Full Text
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Kalady, M. F., M. W. Onaitis, C. R. Mantyh, D. S. Tyler, and K. A. Ludwig. “Coloanal anastomotic integrity after total mesorectal excision is not compromised by preoperative chemoradiation for rectal cancer.” In Diseases of the Colon & Rectum, 48:601–2. SPRINGER, 2005.Link to Item
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Kalady, Mathhew F., Mark W. Onaitis, Zeinab Abdul-Wahab, Sirisha Emani, Scott K. Pruitt, and Douglas S. Tyler. “Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific anti-pancreatic cancer T cells.” In Gastroenterology, 124:A788–A788. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)83977-x.Full Text
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Onaitis, Mark W., Douglas S. Tyler, Edward Coleman, Peggy Cotton, and Bryan M. Clary. “Improved survival in patients with colorectal metastases to the liver undergoing preoperative FDG-PET.” In Gastroenterology, 124:A825–A825. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)84160-4.Full Text
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Safford, S. D., R. E. Coleman, J. P. Gockerman, J. Moore, J. Feldman, M. W. Onaitis, D. S. Tyler, and J. A. Olson. “I-131-meta-iodobenzylguanidine treatment for metastatic carcinoid tumors in 98 patients.” In Annals of Surgical Oncology, 10:S12–S12. LIPPINCOTT WILLIAMS & WILKINS, 2003.Link to Item
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Kalady, M. F., R. C. Fields, K. B. Wilkins, M. W. Onaitis, D. S. Tyler, C. R. Mantyh, and K. Ludwig. “Routine contrast imaging of low pelvic anastomosis before temporary stoma closure: Lack of clinical impact on patient management.” In Gastroenterology, 123:29–29. W B SAUNDERS CO, 2002.Link to Item
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Kalady, M. F., M. W. Onaitis, J. K. Howden, J. Baillie, P. S. Jowell, M. S. Branch, T. N. Pappas, and D. S. Tyler. “Pancreatic duct strictures without an associated common bile duct stricture: Identifying risk of malignancy.” In Annals of Surgical Oncology, 9:S12–13. LIPPINCOTT WILLIAMS & WILKINS, 2002.Link to Item
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Kalady, M. F., D. C. White, M. W. Onaitis, E. Coleman, H. F. Seigler, and D. Tyler. “Validation of delayed sentinel lymph node mapping for melanoma.” In Cancer Journal, 7:521–22. JONES AND BARTLETT PUBLISHERS, 2001.Link to Item
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Daniels, Larkin J., Elizabeth K. O’Halloran, Mark W. Onaitis, and Steve Eubanks. “Laparoscopic heller myotomy as an effective and durable treatment for achalasia: The Duke University Experience.” In Gastroenterology, 120:A479–A479. Elsevier BV, 2001. https://doi.org/10.1016/s0016-5085(08)82373-6.Full Text
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