Skip to main content

Mark William Onaitis

Adjunct Associate Professor in the Department of Surgery
Surgery, Cardiovascular and Thoracic Surgery
Box 3305 Med Ctr, Durham, NC 27710
Dept of Surgery, Durham, NC 27710

Overview


Mouse Models of Foregut Malignancies
Normal Tissue and Cancer Stem Cells
Risk Prediction in Thoracic Malignancies

Current Appointments & Affiliations


Adjunct Associate Professor in the Department of Surgery · 2016 - Present Surgery, Cardiovascular and Thoracic Surgery, Surgery
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

Recent Publications


Lobectomy vs Sublobar Resection in The Society of Thoracic Surgeons Database: Importance of Patient Factors and Lymph Node Evaluation.

Journal Article Ann Thorac Surg · January 24, 2025 BACKGROUND: Prospective randomized trials have demonstrated noninferior survival between sublobar resection and lobectomy in healthy patients with non-small cell lung cancer with tumors ≤2 cm. However, some patient attributes are not well represented in ra ... Full text Link to item Cite

NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2025.

Journal Article J Natl Compr Canc Netw · January 2025 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Lung Cancer Screening provide criteria for selecting individuals for screening and offer recommendations for evaluating and managing lung nodules detected during initial and subsequent ... Full text Link to item Cite

Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.

Journal Article Cancer Res · May 15, 2024 UNLABELLED: Cancer stem/tumor-initiating cells display stress tolerance and metabolic flexibility to survive in a harsh environment with limited nutrient and oxygen availability. The molecular mechanisms underlying this phenomenon could provide targets to ... Full text Link to item Cite
View All Publications

Recent Grants


National Longitudinal Outcomes Following Surgical Therapy for Lung Cancer

ResearchCo Investigator · Awarded by Society of Thoracic Surgeons · 2014 - 2019

Targeting Integrator Kinases in Lung Cancer Metastasis

ResearchCo-Principal Investigator · Awarded by Free to Breathe · 2015 - 2018

Anti-CTGF Therapy for Squamous Cell Lung Cancer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2017

View All Grants

Education, Training & Certifications


Duke University, School of Medicine · 2010 M.H.S.
Duke University · 1997 M.D.