Scholars@Duke

• Background
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  Education, Training, & Certifications

  • M.D., Stanford University 1978
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  Duke Appointment History

  • Chief, Division of VA Anesthesiology, Anesthesiology, VA Anesthesiology Service, Anesthesiology 1992 - 2018
  • Associate Professor of Anesthesiology, Anesthesiology, VA Anesthesiology Service, Anesthesiology 1999 - 2002
  • Assistant Professor in Medicine, Medicine, Clinical Science Departments 1994 - 1999
  • Associate Professor of Anesthesiology, Anesthesiology, VA Anesthesiology Service, Anesthesiology 1992 - 1999
• Research
• 

  Selected Grants

  • Nurse Anesthetist Program 2000 - 2003
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Hatton, Kevin W., Suraj Yalamuri, Sharon McCartney, Eugene A. Hessel, and Jonathan B. Mark. “Oscillating Continuous Cardiac Output in Postoperative Critically Ill Patients: Is this Phenomenon Accurate, Artifact, or Error?.” J Cardiothorac Vasc Anesth 31, no. 4 (August 2017): e61–62. https://doi.org/10.1053/j.jvca.2017.02.040.
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    • Mark, Jonathan B. “Use of Pressure Transducers..” N Engl J Med 377, no. 4 (July 27, 2017): 400–401. https://doi.org/10.1056/NEJMc1705833.
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    • Segall, Noa, Alberto S. Bonifacio, Atilio Barbeito, Rebecca A. Schroeder, Sharon R. Perfect, Melanie C. Wright, James D. Emery, B Zane Atkins, Jeffrey M. Taekman, and Jonathan B. Mark. “Operating Room-to-ICU Patient Handovers: A Multidisciplinary Human-Centered Design Approach..” Jt Comm J Qual Patient Saf 42, no. 9 (September 2016): 400–414.
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    • Asgarian, Camellia D., Susan M. Martinelli, Jonathan B. Mark, and Priya A. Kumar. “Partial Anomalous Hepatic Venous Return: A Systematic Intraoperative Exclusion of Other Serious Diagnoses..” Anesth Analg 122, no. 2 (February 2016): 349–53. https://doi.org/10.1213/ANE.0000000000001051.
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    • Maxwell, C., R. Konoske, and J. Mark. “Emerging Concepts in Transesophageal Echocardiography.” F1000research 5 (January 1, 2016). https://doi.org/10.12688/f1000research.7169.1.
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    • Barbeito, Atilio, Alberto Bonifacio, Mary Holtschneider, Noa Segall, Rebecca Schroeder, Jonathan Mark, and Jonathan Durham Veterans Affairs Medical Center Patient Safety Center of Inquiry. “In situ simulated cardiac arrest exercises to detect system vulnerabilities..” Simul Healthc 10, no. 3 (June 2015): 154–62. https://doi.org/10.1097/SIH.0000000000000087.
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    • Whitener, Stephanie, Ryan Konoske, and Jonathan B. Mark. “Pulmonary artery catheter..” Best Pract Res Clin Anaesthesiol 28, no. 4 (December 2014): 323–35. https://doi.org/10.1016/j.bpa.2014.08.003.
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    • Barbeito, Atilio, William Travis Lau, Nathaen Weitzel, James H. Abernathy, Joyce Wahr, and Jonathan B. Mark. “FOCUS: the Society of Cardiovascular Anesthesiologists' initiative to improve quality and safety in the cardiovascular operating room..” Anesth Analg 119, no. 4 (October 2014): 777–83. https://doi.org/10.1213/ANE.0000000000000359.
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    • Bonifacio, Alberto S., Noa Segall, Atilio Barbeito, Jeffrey Taekman, Rebecca Schroeder, and Jonathan B. Mark. “Handovers from the OR to the ICU..” Int Anesthesiol Clin 51, no. 1 (2013): 43–61. https://doi.org/10.1097/AIA.0b013e31826f2b0e.
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    • Segall, Noa, Alberto S. Bonifacio, Rebecca A. Schroeder, Atilio Barbeito, Dawn Rogers, Deirdre K. Thornlow, James Emery, et al. “Can we make postoperative patient handovers safer? A systematic review of the literature..” Anesth Analg 115, no. 1 (July 2012): 102–15. https://doi.org/10.1213/ANE.0b013e318253af4b.
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    • American Society of Anesthesiologists Task Force on Central Venous Access, Avery, Stephen M. Rupp, Jeffrey L. Apfelbaum, Casey Blitt, Robert A. Caplan, Richard T. Connis, Karen B. Domino, et al. “Practice guidelines for central venous access: a report by the American Society of Anesthesiologists Task Force on Central Venous Access..” Anesthesiology 116, no. 3 (March 2012): 539–73. https://doi.org/10.1097/ALN.0b013e31823c9569.
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    • Wright, M. C., N. Segall, J. B. Mark, and J. M. Taekman. “Qualitative and task analytic methods to support comprehensible intelligent system design.” Isda 2009  9th International Conference on Intelligent Systems Design and Applications, December 1, 2009, 444–49. https://doi.org/10.1109/ISDA.2009.173.
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    • Barbeito, Atilio, Shahar Bar-Yosef, James E. Lowe, Broadus Z. Atkins, and Jonathan B. Mark. “Unusual cause of superior vena cava syndrome diagnosed with transesophageal echocardiography..” Can J Anaesth 55, no. 11 (November 2008): 774–78. https://doi.org/10.1007/BF03016351.
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    • Segall, N., J. M. Taekman, J. B. Mark, G. Hobbs, and M. C. Wright. “Coding and visualizing eye tracking data in simulated anesthesia care.” Proceedings of the Human Factors and Ergonomics Society 2 (December 1, 2007): 765–69.
    • Welsby, Ian J., Robert Jones, John Pylman, Jonathan B. Mark, Charles S. Brudney, Barbara Phillips-Bute, Joseph P. Mathew, Mary Lee Campbell, Mark Stafford-Smith, and Mark Cardiothoracic Anesthesiology Research Endeavours (C.A.R.E.), Department of Anesthesiology, Duke University Medical Center. “ABO blood group and bleeding after coronary artery bypass graft surgery..” Blood Coagul Fibrinolysis 18, no. 8 (December 2007): 781–85. https://doi.org/10.1097/MBC.0b013e3282f1029c.
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    • Barbeito, Atilio, and Jonathan B. Mark. “Arterial and central venous pressure monitoring..” Anesthesiol Clin 24, no. 4 (December 2006): 717–35.
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    • Wright, M. C., B. Phillips-Bute, J. B. Mark, M. Stafford-Smith, K. P. Grichnik, B. C. Andregg, and J. M. Taekman. “Time of day effects on the incidence of anesthetic adverse events..” Qual Saf Health Care 15, no. 4 (August 2006): 258–63. https://doi.org/10.1136/qshc.2005.017566.
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    • Schroeder, Rebecca A., and Jonathan B. Mark. “Is the valve OK or not? Immediate evaluation of a replaced aortic valve..” Anesth Analg 101, no. 5 (November 2005): 1288–91. https://doi.org/10.1213/01.ANE.0000181339.39448.F0.
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    • Melnick, Abigail H., Marek Brzezinski, and Jonathan B. Mark. “Incidental cor triatriatum sinister during coronary artery bypass surgery..” Anesth Analg 101, no. 3 (September 2005): 637–38. https://doi.org/10.1213/01.ANE.0000175207.19332.6C.
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    • Pittman, James, Shahar Bar-Yosef, John SumPing, Matthew Sherwood, and Jonathan Mark. “Continuous cardiac output monitoring with pulse contour analysis: a comparison with lithium indicator dilution cardiac output measurement..” Crit Care Med 33, no. 9 (September 2005): 2015–21. https://doi.org/10.1097/01.ccm.0000179021.36805.1f.
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    • Mark, Jonathan B. “Multimodal detection of perioperative myocardial ischemia..” Tex Heart Inst J 32, no. 4 (2005): 461–66.
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    • Wright, M. C., B. C. Andregg, J. B. Mark, M. Stafford-Smith, K. P. Grichnik, B. Phillips-Bute, and J. M. Taekman. “Effects of time of day and surgery duration on adverse events in anaesthesia.” Healthcare Systems Ergonomics and Patient Safety: Human Factor, a Bridge Between Care and Cure  Proceedings of the International Conference Heps 2005, 2005, 377–80.
    • Pittman, James A. L., John Sum Ping, and Jonathan B. Mark. “Arterial and central venous pressure monitoring..” Int Anesthesiol Clin 42, no. 1 (2004): 13–30.
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    • American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization, N. D. “Practice guidelines for pulmonary artery catheterization: an updated report by the American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization..” Anesthesiology 99, no. 4 (October 2003): 988–1014. https://doi.org/10.1097/00000542-200310000-00036.
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    • Mark, J. B. “Interpretation of hemodynamic monitoring.” Anesthesia and Analgesia 96, no. 3 (March 1, 2003): 56–59.
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    • Faehnrich, Jana A., Robert B. Noone, William D. White, Bruce J. Leone, Andrew K. Hilton, Gautam M. Sreeram, and Jonathan B. Mark. “Effects of positive-pressure ventilation, pericardial effusion, and cardiac tamponade on respiratory variation in transmitral flow velocities..” J Cardiothorac Vasc Anesth 17, no. 1 (February 2003): 45–50. https://doi.org/10.1053/jcan.2003.9.
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    • Aronson, Solomon, Aggie Butler, Raja Subhiyah, Richard E. Buckingham, Michael K. Cahalan, Steven Konstandt, Jonathan Mark, et al. “Development and analysis of a new certifying examination in perioperative transesophageal echocardiography..” Anesth Analg 95, no. 6 (December 2002): 1476–82. https://doi.org/10.1097/00000539-200212000-00004.
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    • Garcia-Rodriguez, Charles, James Pittman, Cynthia H. Cassell, John Sum-Ping, Habib El-Moalem, Christopher Young, and Jonathan B. Mark. “Lithium dilution cardiac output measurement: a clinical assessment of central venous and peripheral venous indicator injection..” Crit Care Med 30, no. 10 (October 2002): 2199–2204. https://doi.org/10.1097/00003246-200210000-00004.
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    • Slaughter, T. F., J. B. Mark, H. El-Moalem, K. A. Hayward, A. K. Hilton, L. P. Hodgins, and C. S. Greenberg. “Hemostatic effects of antithrombin III supplementation during cardiac surgery: results of a prospective randomized investigation..” Blood Coagul Fibrinolysis 12, no. 1 (January 2001): 25–31.
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    • Slaughter, T. F., J. B. Mark, M. J. Jacka, and A. Clark. “Heparin-mediated hypotension associated with cardiac surgery [8] (multiple letters).” Anesthesia and Analgesia 91, no. 3 (September 19, 2000): 766–67.
    • Garcia-Rodriguez, C., C. Cassell, C. Young, J. S. Ping, and J. B. Mark. “Cardiac output measurement without pulmonary artery or central venous catheterization: A clinical assessment of the lithium dilution method.” Anesthesiology 93, no. 3A (September 1, 2000): U166–U166.
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    • Garcia-Rodriguez, C., C. Cassell, C. Young, J. S. Ping, and J. B. Mark. “Cardiac output measurement without pulmonary artery or central venous catheterization: A clinical assessment of the lithium dilution method.” Anesthesiology, September 2000.
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    • Slaughter, T. F., and J. B. Mark. “Heparin-mediated hypotension associated with cardiac surgery..” Anesth Analg 91, no. 3 (September 2000): 766–67. https://doi.org/10.1097/00000539-200009000-00063.
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    • Young, C. C., C. R. Garcia-Rodriguez, C. Cassell, H. El-Moalem, and J. B. Mark. “Lithium dilution versus thermodilution cardiac output measurement in cardiac surgery patients.” Anesthesiology 93, no. 3A (September 1, 2000): U166–U166.
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    • Young, C. C., C. R. Garcia-Rodriguez, C. Cassell, H. El-Moalem, and J. B. Mark. “Lithium dilution versus thermodilution cardiac output measurement in cardiac surgery patients.” Anesthesiology, September 2000.
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    • Shanewise, J. S., A. T. Cheung, S. Aronson, W. J. Stewart, R. L. Weiss, J. B. Mark, R. M. Savage, et al. “ASE/SCA guidelines for performing a comprehensive intraoperative multiplane transesophageal echocardiography examination: recommendations of the American Society of Echocardiography Council for Intraoperative Echocardiography and the Society of Cardiovascular Anesthesiologists Task Force for Certification in Perioperative Transesophageal Echocardiography..” J Am Soc Echocardiogr 12, no. 10 (October 1999): 884–900.
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    • Shanewise, J. S., A. T. Cheung, S. Aronson, W. J. Stewart, R. L. Weiss, J. B. Mark, R. M. Savage, et al. “ASE/SCA guidelines for performing a comprehensive intraoperative multiplane transesophageal echocardiography examination: recommendations of the American Society of Echocardiography Council for Intraoperative Echocardiography and the Society of Cardiovascular Anesthesiologists Task Force for Certification in Perioperative Transesophageal Echocardiography..” Anesth Analg 89, no. 4 (October 1999): 870–84. https://doi.org/10.1097/00000539-199910000-00010.
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    • Heine, T. A., B. L. Halambeck, and J. B. Mark. “Fatal pulmonary fat embolism in the early postoperative period..” Anesthesiology 89, no. 6 (December 1998): 1589–91. https://doi.org/10.1097/00000542-199812000-00046.
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    • Lineberger, C. K., J. B. Mark, and J. G. Reves. “Anesthesia education class sizes: Estimates from the workforce perspective.” Problems in Anesthesia 10, no. 3 (July 1, 1998): 351–60.
    • Watke, C. M., J. B. Mark, A. K. Hilton, L. R. Hodgins, H. El- Moalem, and T. F. Slaughter. “Effects of antithrombin III supplementation on hemostatic activation in cardiac surgical patients.” Anesthesia and Analgesia 86, no. 4 (April 1, 1998): SCA30–SCA30.
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    • Faehnrich, J. A., R. B. Noone, W. D. White, B. J. Leone, A. K. Hilton, and J. B. Mark. “Is increased respiratory variation in transmitral flow a reliable sign of cardiac tamponade during positive pressure ventilation?.” Anesthesiology 85, no. 3A (September 1, 1996): A89–A89.
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    • Slaughter, T. F., H. Grocott, K. Greenblo, E. BennettGuerrero, A. Hilton, L. Hodgins, and J. B. Mark. “The heparin management test (HMT): An improved method for monitoring anticoagulation during cardiac surgery.” Anesthesiology 85, no. 3A (September 1, 1996): A148–A148.
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    • DeNofrio, D., A. F. Ament, J. B. Mark, and S. E. George. “Accelerated TPA for treatment of prosthetic valve thrombosis..” Clin Cardiol 19, no. 8 (August 1996): 665–68. https://doi.org/10.1002/clc.4960190816.
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    • Hilton, A. K., G. H. Botz, M. W. Krucoff, and J. B. Mark. “Continuous 12-lead ECG fingerprint of the post-coronary artery bypass graft (CABG) patient.” Anesthesia and Analgesia 82, no. 4 (April 1, 1996): SCA44–SCA44.
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    • Young, C. C., J. B. Mark, W. White, A. DeBree, J. S. Vender, and A. Fleming. “Clinical evaluation of continuous noninvasive blood pressure monitoring: accuracy and tracking capabilities..” J Clin Monit 11, no. 4 (July 1995): 245–52.
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    • Mark, J. B., S. U. Ahmed, R. Kluger, and S. M. Robinson. “Influence of jet direction on pulmonary vein flow patterns in severe mitral regurgitation..” Anesth Analg 80, no. 3 (March 1995): 486–91. https://doi.org/10.1097/00000539-199503000-00009.
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    • Dentz, M. E., T. F. Slaughter, and J. B. Mark. “Early thrombus formation on heparin-bonded pulmonary artery catheters in patients receiving epsilon aminocaproic acid..” Anesthesiology 82, no. 2 (February 1995): 583–86. https://doi.org/10.1097/00000542-199502000-00030.
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    • Hodgins, L., J. A. Kisslo, and J. B. Mark. “Perioperative transesophageal echocardiography: the anesthesiologist as cardiac diagnostician..” Anesth Analg 80, no. 1 (January 1995): 4–6. https://doi.org/10.1097/00000539-199501000-00002.
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    • Sutton, D. C., R. Kluger, S. U. Ahmed, S. C. Reimold, and J. B. Mark. “Flow reversal in the descending aorta: a guide to intraoperative assessment of aortic regurgitation with transesophageal echocardiography..” J Thorac Cardiovasc Surg 108, no. 3 (September 1994): 576–82.
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    • Mark, J. B., and R. Spillane. “Interluminal communication in a pulmonary artery catheter causing artifactual pressure measurement..” Anesth Analg 78, no. 6 (June 1994): 1184–86. https://doi.org/10.1213/00000539-199406000-00030.
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    • Slaughter, T. F., J. B. Mark, and J. G. Reves. “Pituitary apoplexy and the conflicting perioperative goals of anticoagulation and hemostasis..” Anesth Analg 76, no. 3 (March 1993): 470–71. https://doi.org/10.1213/00000539-199303000-00003.
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    • “Practice guidelines for pulmonary artery catheterization. A report by the American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization..” Anesthesiology 78, no. 2 (February 1993): 380–94.
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    • Hickey, C., L. D. Gugino, L. S. Aglio, J. B. Mark, S. L. Son, and R. Maddi. “Intraoperative somatosensory evoked potential monitoring predicts peripheral nerve injury during cardiac surgery..” Anesthesiology 78, no. 1 (January 1993): 29–35. https://doi.org/10.1097/00000542-199301000-00006.
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    • Burke, R. P., J. B. Mark, J. J. Collins, and L. H. Cohn. “Improved surgical approach to left atrial appendage aneurysm..” J Card Surg 7, no. 2 (June 1992): 104–7.
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    • Mark, J. B., G. L. Chien, R. A. Steinbrook, and T. Fenton. “Electrocardiographic R-wave changes during cardiac surgery..” Anesth Analg 74, no. 1 (January 1992): 26–31. https://doi.org/10.1213/00000539-199201000-00005.
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    • Mark, J. B., D. FitzGerald, T. Fenton, A. M. Fosberg, W. Camann, N. Maffeo, and J. Winkelman. “Continuous arterial and venous blood gas monitoring during cardiopulmonary bypass..” J Thorac Cardiovasc Surg 102, no. 3 (September 1991): 431–39.
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    • Steinbrook, R. A., D. B. Goldman, J. B. Mark, J. H. Philip, and D. B. Raemer. “How best to monitor for detection of myocardial ischemia?.” Anesthesiology 74, no. 6 (June 1991): 1171–72. https://doi.org/10.1097/00000542-199106000-00055.
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    • Mark, J. B. “Central venous pressure monitoring: clinical insights beyond the numbers..” J Cardiothorac Vasc Anesth 5, no. 2 (April 1991): 163–73.
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    • Mark, J. B., and P. M. Chetham. “Ventricular pacing can induce hemodynamically significant mitral valve regurgitation..” Anesthesiology 74, no. 2 (February 1991): 375–77. https://doi.org/10.1097/00000542-199102000-00030.
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    • Grayzel, J., and J. B. Mark. “The cardiac cycle [4].” Journal of Cardiothoracic and Vascular Anesthesia 5, no. 6 (1991): 649–51. https://doi.org/10.1016/1053-0770(91)90028-R.
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    • Mark, J. B. “Response.” Journal of Cardiothoracic and Vascular Anesthesia 5, no. 6 (January 1, 1991). https://doi.org/10.1016/1053-0770(91)90029-S.
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    • Maddi, R., J. C. Horrow, J. B. Mark, M. Concepcion, and E. Murray. “Evaluation of a new cutaneous topical anesthesia preparation..” Reg Anesth 15, no. 3 (May 1990): 109–12.
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    • Mark, J. B., S. M. Steele, M. A. Concepcion, D. Raemer, and M. K. Patterson. “Mechanism of arterial hypotension during spinal anesthesia.” Regional Anesthesia 15, no. 1 (January 1, 1990): 54–55.
    • Mushlin, P. S., J. B. Mark, W. R. Elliott, S. Striz, D. B. Goldman, and J. Philip. “Inadvertent development of subatmospheric airway pressure during cardiopulmonary bypass..” Anesthesiology 71, no. 3 (September 1989): 459–62. https://doi.org/10.1097/00000542-198909000-00028.
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    • Mark, J. B. “Systolic venous waves cause spurious signs of arterial hemoglobin desaturation..” Anesthesiology 71, no. 1 (July 1989): 158–60. https://doi.org/10.1097/00000542-198907000-00025.
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    • Mark, J. B., and S. M. Steele. “Cardiovascular effects of spinal anesthesia..” Int Anesthesiol Clin 27, no. 1 (1989): 31–39.
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    • Mark, J. B., J. C. Horrow, P. D. Eckenbrecht, M. Smalky, G. R. Arthur, U. Dhingra, and E. Murray. “Anesthetic induction with fentanyl and intravenous lidocaine for coronary artery surgery..” J Cardiothorac Anesth 1, no. 6 (December 1987): 517–23.
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    • Camann, W. R., S. R. Wojtowicz, and J. B. Mark. “Reoperation for coronary artery bypass grafting: anesthetic challenge..” J Cardiothorac Anesth 1, no. 5 (October 1987): 458–67.
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    • Cohen, M. B., J. B. Mark, R. W. Morris, and E. Frank. “Introducer sheath malfunction producing insidious air embolism..” Anesthesiology 67, no. 4 (October 1987): 573–75. https://doi.org/10.1097/00000542-198710000-00023.
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    • DiSesa, V. J., J. B. Mark, J. P. Gold, F. Kidwell, R. J. Shemin, J. J. Collins, and L. H. Cohn. “Nitrous oxide for blood pressure control after coronary artery surgery: a dose-response hemodynamic study in postoperative patients..” Ann Thorac Surg 44, no. 2 (August 1987): 189–91. https://doi.org/10.1016/s0003-4975(10)62039-5.
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    • Mark, J. B., R. A. Steinbrook, L. D. Gugino, R. Maddi, B. Hartwell, R. Shemin, V. DiSesa, and W. N. Rida. “Continuous noninvasive monitoring of cardiac output with esophageal Doppler ultrasound during cardiac surgery..” Anesth Analg 65, no. 10 (October 1986): 1013–20.
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    • Hartwell, B. L., and J. B. Mark. “Combinations of beta-blockers and calcium channel blockers: a cause of malignant perioperative conduction disturbances?.” Anesth Analg 65, no. 8 (August 1986): 905–7.
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    • DiSesa, V. J., J. P. Gold, and J. B. Mark. “Respiratory and hemodynamic effects of nitrous oxide: A dose-response study in patients following cardiac operation.” Surgical Forum VOL. 36 (January 1, 1985): 243–45.
    • Raemer, D. B., J. C. Horrow, J. B. Mark, R. Maddi, J. J. Collins, and S. L. Son. “A new surgical monitoring and resuscitation cart..” Med Instrum 18, no. 3 (May 1984): 189–90.
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    • Mark, J. B., and L. M. Greenberg. “Intraoperative awareness and hypertensive crisis during high-dose fentanyl-diazepam-oxygen anesthesia..” Anesth Analg 62, no. 7 (July 1983): 698–700.
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  • Book Sections

    • Fink, R. J., and J. B. Mark. “Standard anesthesia monitoring techniques and instruments.” In Clinical Anesthesia Fundamentals, 2015.
    • Atkins, M. E., and J. B. Mark. “Invasive hemodynamic monitoring.” In Core Topics in Cardiac Anesthesia, Second Edition, 141–46, 2012. https://doi.org/10.1017/CBO9780511979095.028.
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    • Karhausen, J., and J. B. Mark. “Routine clinical monitoring.” In Core Topics in Cardiac Anesthesia, Second Edition, 133–40, 2012. https://doi.org/10.1017/CBO9780511979095.027.
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  • Conference Papers

    • Pyati, Srini, Atilio Barbeito, Bonifacio Al, Rebecca Schroeder, and Jonathan B. Mark. “A Program to Teach Moderate Sedation in the Gastrointestinal Endoscopy Suite.” In British Journal of Anaesthesia, 108:366–67. OXFORD UNIV PRESS, 2012.
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    • Pittman, J. A. L., J. S. Sum-Ping, M. W. Sherwood, H. El-Moalem, and J. B. Mark. “The accuracy of cardiac output monitoring by pulse contour analysis in intensive care.” In Intensive Care Medicine, 28:S78–S78. SPRINGER-VERLAG, 2002.
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