Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Pulmonary and Critical Care Medicine, Medicineq, Duke University 1995 - 1998
  • Chief Medical Resident, Medicine, University of Alabama at Birmingham 1994 - 1995
  • Medical Resident, Medicine, University of Alabama at Birmingham 1991 - 1994
  • M.D., Wake Forest University 1991
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2010 - 2011
  • Assistant Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2001 - 2010
  • Associate in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 1998 - 2001
  • Instructor, Temporary in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 1998
• Research
• 

  Selected Grants

  • Role of S-nitrosothiols in Akt1 signaling and pneumonia resolution awarded by National Institutes of Health 2017 - 2021
  • Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2020
  • S-nitrosothiols, NF-KappaB and Inflammation in Acute Lung Injury awarded by National Institutes of Health 2014 - 2019
  • S-nitrosothiol-regulated pathways in acute lung injury awarded by National Institutes of Health 2010 - 2013
  • Regulation of NF-Kappa B by Nirtic oxide in the lung awarded by National Institutes of Health 2000 - 2006
• Publications & Artistic Works
• 

  Selected Publications

  • Journal Articles

    • Kelleher, ZT, Sha, Y, Foster, MW, Foster, WM, Forrester, MT, and Marshall, HE. "Thioredoxin-mediated denitrosylation regulates cytokine-induced nuclear factor κB (NF-κB) activation." The Journal of Biological Chemistry 289, no. 5 (January 2014): 3066-3072.  Full Text
    • Foster, MW, Thompson, JW, Forrester, MT, Sha, Y, McMahon, TJ, Bowles, DE, Moseley, MA, and Marshall, HE. "Proteomic analysis of the NOS2 interactome in human airway epithelial cells." Nitric Oxide 34 (November 2013): 37-46.  Full Text
    • Foster, MW, Thompson, JW, Forrester, MT, Sha, Y, McMahon, TJ, Bowles, DE, Moseley, MA, and Marshall, HE. "Proteomic analysis of the NOS2 interactome in human airway epithelial cells." Nitric oxide : biology and chemistry 34 (November 2013): 37-46.  Full Text
    • Foster, MW, Thompson, JW, Que, LG, Yang, IV, Schwartz, DA, Moseley, MA, and Marshall, HE. "Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure." J Proteome Res 12, no. 5 (May 3, 2013): 2194-2205.  Full Text  Link to Item
    • Marshall, HE, and Foster, MW. "S-nitrosylation of Ras in breast cancer. (Published online)" Breast Cancer Res 14, no. 6 (November 12, 2012): 113-.  Full Text  Link to Item
    • Marshall, HE, and Gow, A. "Regulation of cellular processes by S-nitrosylation. Preface." Biochim Biophys Acta 1820, no. 6 (June 2012): 673-674.  Full Text  Link to Item
    • Sha, Y, and Marshall, HE. "S-nitrosylation in the regulation of gene transcription." Biochim Biophys Acta 1820, no. 6 (June 2012): 701-711.  Full Text  Link to Item
    • Yang, IV, Tomfohr, J, Singh, J, Foss, CM, Marshall, HE, Que, LG, McElvania-Tekippe, E, Florence, S, Sundy, JS, and Schwartz, DA. "The clinical and environmental determinants of airway transcriptional profiles in allergic asthma." American Journal of Respiratory and Critical Care Medicine 185, no. 6 (March 2012): 620-627.  Full Text
    • Kelleher, ZT, Potts, EN, Brahmajothi, MV, Foster, MW, Auten, RL, Foster, WM, and Marshall, HE. "NOS2 regulation of LPS-induced airway inflammation via S-nitrosylation of NF-{kappa}B p65." American Journal of Physiology. Lung Cellular and Molecular Physiology 301, no. 3 (September 2011): L327-L333.  Full Text
    • Forrester, MT, Seth, D, Hausladen, A, Eyler, CE, Foster, MW, Matsumoto, A, Benhar, M, Marshall, HE, and Stamler, JS. "Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation." The Journal of Biological Chemistry 284, no. 52 (December 2009): 36160-36166.  Full Text
    • Marshall, HE, Potts, EN, Kelleher, ZT, Stamler, JS, Foster, WM, and Auten, RL. "Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols." American Journal of Respiratory and Critical Care Medicine 180, no. 1 (July 2009): 11-18.  Full Text
    • Kelleher, ZT, Matsumoto, A, Stamler, JS, and Marshall, HE. "NOS2 regulation of NF-kappaB by S-nitrosylation of p65." J Biol Chem 282, no. 42 (October 19, 2007): 30667-30672.  Full Text  Link to Item
    • Hess, DT, Matsumoto, A, Kim, S-O, Marshall, HE, and Stamler, JS. "Protein S-nitrosylation: purview and parameters." Nature Reviews. Molecular Cell Biology 6, no. 2 (February 2005): 150-166. (Review)  Full Text
    • Marshall, HE, Hess, DT, and Stamler, JS. "S-nitrosylation: physiological regulation of NF-kappaB." Proceedings of the National Academy of Sciences of the United States of America 101, no. 24 (June 8, 2004): 8841-8842. (Review)  Full Text
    • Liu, L, Yan, Y, Zeng, M, Zhang, J, Hanes, MA, Ahearn, G, McMahon, TJ, Dickfeld, T, Marshall, HE, Que, LG, and Stamler, JS. "Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock." Cell 116, no. 4 (February 2004): 617-628.  Full Text
    • Marshall, HE, and Stamler, JS. "Nitrosative stress-induced apoptosis through inhibition of NF-kappa B." J Biol Chem 277, no. 37 (September 13, 2002): 34223-34228.  Full Text  Link to Item
    • Marshall, HE, and Stamler, JS. "Inhibition of NF-kappa B by S-nitrosylation." Biochemistry 40, no. 6 (February 13, 2001): 1688-1693.  Link to Item
    • Marshall, HE, Merchant, K, and Stamler, JS. "Nitrosation and oxidation in the regulation of gene expression." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 14, no. 13 (October 2000): 1889-1900. (Review)  Full Text
    • Marshall, HE, and Stamler, JS. "NO waiting to exhale in asthma." Am J Respir Crit Care Med 161, no. 3 Pt 1 (March 2000): 685-687.  Full Text  Link to Item
    • Marshall, HE, and Stamler, JS. "NO waiting to exhale in asthma." American Journal of Respiratory and Critical Care Medicine 161, no. 3 I (2000): 685-687.
    • Marshall, HE, and Stamler, JS. "Exhaled nitric oxide (NO), NO synthase activity, and regulation of nuclear factor (NF)-kappaB." Am J Respir Cell Mol Biol 21, no. 3 (September 1999): 296-297. (Review)  Full Text  Link to Item
    • Marshall, HE, Keenan, KP, and McDowell, EM. "The stathmokinetic and morphological response of the hamster respiratory epithelium to intralaryngeal instillations of saline and ferric oxide in saline." Fundam Appl Toxicol 9, no. 4 (November 1987): 705-714.  Link to Item
    • III, HEM, Keenan, KP, and McDowell, EM. "The stathmokinetic and morphological response of the hamster respiratory epithelium to intralaryngeal instillations of saline and ferric oxide in saline." Fundamental and Applied Toxicology 9, no. 4 (1987): 705-714.
• Teaching & Mentoring
• 

  Recent Courses

  • MEDICINE 430C: Pulmonary Medicine 2018

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