Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Duke University 1992
  • M.A., University of Virginia 1988
• 

  Previous Appointments & Affiliations

  • Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2016 - 2020
  • Chief, Division of Translational Neuroscience, Psychiatry & Behavioral Sciences, Clinical Science Departments 2012 - 2020
  • Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2010 - 2015
  • Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2007 - 2010
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2001 - 2007
• Research
• 

  Selected Grants

  • Novel Intervention for Chronic Complex TBI in OEF/OIF/OND Veterans awarded by Department of Defense 2022 - 2026
  • VA Research Service Agreement (Doug Williamson) awarded by Durham Veterans Affairs Medical Center 2022 - 2023
  • Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
  • VA Research Service Agreement (Doug Williamson) awarded by Durham Veterans Affairs Medical Center 2021 - 2022
  • IPA - Susan Helene O'Loughlin awarded by Durham Veterans Affairs Medical Center 2021 - 2022
  • Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders awarded by University of Texas - Southwestern 2018 - 2022
  • VA Research Service Agreement (Doug Williamson) awarded by Durham Veterans Affairs Medical Center 2020 - 2021
  • IPA - Brian Thomas Cuffe awarded by Durham Veterans Affairs Medical Center 2019 - 2021
  • IPA - Lawrence Shampine awarded by Durham Veterans Affairs Medical Center 2019 - 2021
  • IPA - Patricia Resick awarded by Veterans Affairs Boston Healthcare System 2020
  • IPA - Jason Kilts awarded by Durham Veterans Affairs Medical Center 2019 - 2020
  • IPA - Larry Allen Tupler awarded by Durham Veterans Affairs Medical Center 2018 - 2020
  • IPA - Rachel Phillips awarded by Durham Veterans Affairs Medical Center 2019
  • IPA - Lawrence Shampine awarded by Veterans Administration Medical Center 2006 - 2008
  • Neurosteroids and Schizophrenia awarded by National Institutes of Health 2001 - 2007
• 

  Fellowships, Supported Research, & Other Grants

  • Biomarker Candidates in Gulf War Veterans: A 10-year Follow-up Investigation awarded by VA Merit Award 2018 - 2022
  • Neurosteroids in PTSD - Biomarkers to Therapeutics awarded by VA Career Development Award to Steven Szabo, MD 2018 - 2023
  • Neurosteroid Intervention in Gulf War Veterans Illnesses (GWVI) awarded by VA Merit Award 2014 - 2017
  • Neuroactive Steroids in OEF/OIF Veterans with TBI awarded by VA Merit Award 2011 - 2016
• 

  External Relationships

  • Invited to give the Edwin Gildea lecture at Washington University on November 15, 2022 (travel was covered and the lectureship provided a 1,000 honorarium)
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Bjork, J. M., P. B. Perrin, M. Redae, L. A. Tupler, M. Brancu, J. C. Beckham, P. S. Calhoun, et al. “Warzone experiences and subsequent clinician suicide risk assessment in veterans.” Suicide and Life Threatening Behavior 51, no. 6 (December 1, 2021): 1067–76. https://doi.org/10.1111/sltb.12789.
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    • Graziano, Robert C., Frances M. Aunon, Stefanie T. LoSavio, Eric B. Elbogen, Jean C. Beckham, Jean C. VA Mid-Atlantic MIRECC Workgroup, and Kirsten H. Dillon. “A network analysis of risk factors for suicide in Iraq/Afghanistan-era veterans.” J Psychiatr Res 138 (June 2021): 264–71. https://doi.org/10.1016/j.jpsychires.2021.03.065.
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    • Dillon, Kirsten H., Elizabeth E. Van Voorhees, Eric B. Elbogen, Jean C. Beckham, Jean C. VA Mid-Atlantic MIRECC Workgroup, and Patrick S. Calhoun. “Cannabis use disorder, anger, and violence in Iraq/Afghanistan-era veterans.” J Psychiatr Res 138 (June 2021): 375–79. https://doi.org/10.1016/j.jpsychires.2021.04.018.
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    • Garrett, Melanie E., Xue Jun Qin, Divya Mehta, Michelle F. Dennis, Christine E. Marx, Gerald A. Grant, Gerald A. VA Mid-Atlantic MIRECC Workgroup, et al. “Gene Expression Analysis in Three Posttraumatic Stress Disorder Cohorts Implicates Inflammation and Innate Immunity Pathways and Uncovers Shared Genetic Risk With Major Depressive Disorder.” Front Neurosci 15 (2021): 678548. https://doi.org/10.3389/fnins.2021.678548.
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    • Rauch, Sheila A. M., Rebecca Sripada, Mark Burton, Vasiliki Michopoulos, Kimberly Kerley, Christine E. Marx, Jason D. Kilts, et al. “Corrigendum to "Neuroendocrine biomarkers of prolonged exposure treatment response in military-related PTSD" [Psychoneuroendocrinology (2020) Article 104749].” Psychoneuroendocrinology 120 (October 2020): 104802. https://doi.org/10.1016/j.psyneuen.2020.104802.
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    • Rauch, Sheila A. M., Rebecca Sripada, Mark Burton, Vasiliki Michopoulos, Kimberly Kerley, Christine E. Marx, Jason D. Kilts, et al. “Neuroendocrine biomarkers of prolonged exposure treatment response in military-related PTSD.” Psychoneuroendocrinology 119 (September 2020): 104749. https://doi.org/10.1016/j.psyneuen.2020.104749.
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    • Fisher, Lauren B., Jessica Bomyea, Garrett Thomas, Joey C. Cheung, Feng He, Sonia Jain, Laura A. Flashman, et al. “Contributions of posttraumatic stress disorder (PTSD) and mild TBI (mTBI) history to suicidality in the INTRuST consortium.” Brain Inj 34, no. 10 (August 23, 2020): 1339–49. https://doi.org/10.1080/02699052.2020.1807054.
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    • Kinzel, Philipp, Christine E. Marx, Nico Sollmann, Elisabeth Hartl, Jeffrey P. Guenette, David Kaufmann, Sylvain Bouix, et al. “Serum Neurosteroid Levels Are Associated With Cortical Thickness in Individuals Diagnosed With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury.” Clin Eeg Neurosci 51, no. 4 (July 2020): 285–99. https://doi.org/10.1177/1550059420909676.
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    • Morey, Rajendra A., Courtney C. Haswell, Daniel Stjepanović, Daniel Mid-Atlantic MIRECC Workgroup, Joseph E. Dunsmoor, and Kevin S. LaBar. “Neural correlates of conceptual-level fear generalization in posttraumatic stress disorder.” Neuropsychopharmacology 45, no. 8 (July 2020): 1380–89. https://doi.org/10.1038/s41386-020-0661-8.
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    • Logue, Mark W., Mark W. Miller, Erika J. Wolf, Bertrand Russ Huber, Filomene G. Morrison, Zhenwei Zhou, Yuanchao Zheng, et al. “An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.” Clin Epigenetics 12, no. 1 (March 14, 2020): 46. https://doi.org/10.1186/s13148-020-0820-0.
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    • Naylor, Jennifer C., Jason D. Kilts, Lawrence J. Shampine, Gillian J. Parke, H Ryan Wagner, Steven T. Szabo, Karen D. Smith, et al. “Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.” Jama Netw Open 3, no. 3 (March 2, 2020): e200287. https://doi.org/10.1001/jamanetworkopen.2020.0287.
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    • Morey, Rajendra A., Emily K. Clarke, Courtney C. Haswell, Rachel D. Phillips, Ashley N. Clausen, Mary S. Mufford, Zeynep Saygin, Zeynep VA Mid-Atlantic MIRECC Workgroup, H Ryan Wagner, and Kevin S. LaBar. “Amygdala Nuclei Volume and Shape in Military Veterans With Posttraumatic Stress Disorder.” Biol Psychiatry Cogn Neurosci Neuroimaging 5, no. 3 (March 2020): 281–90. https://doi.org/10.1016/j.bpsc.2019.11.016.
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    • Clausen, Ashley N., Emily Clarke, Rachel D. Phillips, Courtney Haswell, Courtney VA Mid-Atlantic MIRECC Workgroup, and Rajendra A. Morey. “Combat exposure, posttraumatic stress disorder, and head injuries differentially relate to alterations in cortical thickness in military Veterans.” Neuropsychopharmacology 45, no. 3 (February 2020): 491–98. https://doi.org/10.1038/s41386-019-0539-9.
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    • Rakesh, Gopalkumar, Rajendra A. Morey, Anthony S. Zannas, Zainab Malik, Christine E. Marx, Ashley N. Clausen, Michael D. Kritzer, and Steven T. Szabo. “Resilience as a translational endpoint in the treatment of PTSD.” Mol Psychiatry 24, no. 9 (September 2019): 1268–83. https://doi.org/10.1038/s41380-019-0383-7.
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    • Naylor, Jennifer C., H Ryan Wagner, Cynthia Johnston, Eric E. Elbogen, Mira Brancu, Christine E. Marx, Christine E. VA Mid-Atlantic MIRECC Work Group, Christine E. VA Mid-Atlantic MIRECC Women Veterans Work Group, and Jennifer L. Strauss. “Pain Intensity and Pain Interference in Male and Female Iraq/Afghanistan-era Veterans.” Womens Health Issues 29 Suppl 1 (June 25, 2019): S24–31. https://doi.org/10.1016/j.whi.2019.04.015.
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    • Shura, Robert D., Sarra Nazem, Holly M. Miskey, Trisha A. Hostetter, Jared A. Rowland, Lisa A. Brenner, Lisa A. Va Mid-Atlantic Mirecc Workgroup, and Katherine H. Taber. “Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans.” Psychol Serv 16, no. 2 (May 2019): 312–20. https://doi.org/10.1037/ser0000208.
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    • Epstein, Erica L., Sarah L. Martindale, Sarah L. Va Mid-Atlantic Mirecc Workgroup, and Holly M. Miskey. “Posttraumatic stress disorder and traumatic brain Injury: Sex differences in veterans.” Psychiatry Res 274 (April 2019): 105–11. https://doi.org/10.1016/j.psychres.2019.01.097.
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    • Bomyea, Jessica, Laura A. Flashman, Ross Zafonte, Norberto Andaluz, Raul Coimbra, Mark S. George, Gerald A. Grant, et al. “Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.” Psychiatry Res 272 (February 2019): 531–39. https://doi.org/10.1016/j.psychres.2018.12.021.
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    • Cruz, Dianne A., Leisa A. Glantz, Kara D. McGaughey, Gillian Parke, Lawrence J. Shampine, Jason D. Kilts, Jennifer C. Naylor, Christine E. Marx, and Douglas E. Williamson. “Neurosteroid Levels in the Orbital Frontal Cortex of Subjects with PTSD and Controls: A Preliminary Report.” Chronic Stress (Thousand Oaks) 3 (January 2019). https://doi.org/10.1177/2470547019838570.
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    • Morey, Rajendra A., Sarah L. Davis, Courtney C. Haswell, Jennifer C. Naylor, Jason D. Kilts, Steven T. Szabo, Larry J. Shampine, et al. “Widespread Cortical Thickness Is Associated With Neuroactive Steroid Levels.” Front Neurosci 13 (2019): 1118. https://doi.org/10.3389/fnins.2019.01118.
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    • Sheerin, Christina M., Ananda B. Amstadter, Erin D. Kurtz, Kaitlin E. Bountress, Kelcey J. Stratton, Scott D. McDonald, and Scott D. Mid-Atlantic Va Mirecc Workgroup. “The association of resilience on psychiatric, substance use, and physical health outcomes in combat trauma-exposed military service members and veterans.” Eur J Psychotraumatol 10, no. 1 (2019): 1625700. https://doi.org/10.1080/20008198.2019.1625700.
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    • Martindale, Sarah L., Erica L. Epstein, Katherine H. Taber, Katherine H. VA Mid-Atlantic MIRECC Workgroup, and Jared A. Rowland. “Behavioral and Health Outcomes Associated With Deployment and Nondeployment Acquisition of Traumatic Brain Injury in Iraq and Afghanistan Veterans.” Arch Phys Med Rehabil 99, no. 12 (December 2018): 2485–95. https://doi.org/10.1016/j.apmr.2018.04.029.
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    • Elbogen, Eric B., H Ryan Wagner, Mira Brancu, Nathan A. Kimbrel, Jennifer C. Naylor, Cindy M. Swinkels, Cindy M. VA Mid-Atlantic MIRECC Workgroup, and John A. Fairbank. “Psychosocial Risk Factors and Other Than Honorable Military Discharge: Providing Healthcare to Previously Ineligible Veterans.” Mil Med 183, no. 9–10 (September 1, 2018): e532–38. https://doi.org/10.1093/milmed/usx128.
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    • Swanson, Jeffrey, Michele Easter, Mira Brancu, Mira VA Mid-Atlantic MIRECC Workgroup, and John A. Fairbank. “Informing Federal Policy on Firearm Restrictions for Veterans with Fiduciaries: Risk Indicators in the Post-Deployment Mental Health Study.” Adm Policy Ment Health 45, no. 4 (July 2018): 673–83. https://doi.org/10.1007/s10488-018-0881-y.
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    • Wilson, Sarah M., Thomas K. Burroughs, Amie R. Newins, Eric A. Dedert, Alyssa M. Medenblik, Scott D. McDonald, Jean C. Beckham, Jean C. VA Mid-Atlantic MIRECC Workgroup, and Patrick S. Calhoun. “The Association Between Alcohol Consumption, Lifetime Alcohol Use Disorder, and Psychiatric Distress Among Male and Female Veterans.” J Stud Alcohol Drugs 79, no. 4 (July 2018): 591–600. https://doi.org/10.15288/jsad.2018.79.591.
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    • Lepage, Christian, Amicie de Pierrefeu, Inga K. Koerte, Michael J. Coleman, Ofer Pasternak, Gerald Grant, Christine E. Marx, et al. “White matter abnormalities in mild traumatic brain injury with and without post-traumatic stress disorder: a subject-specific diffusion tensor imaging study.” Brain Imaging Behav 12, no. 3 (June 2018): 870–81. https://doi.org/10.1007/s11682-017-9744-5.
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    • Elbogen, Eric B., H Ryan Wagner, Nathan A. Kimbrel, Mira Brancu, Jennifer Naylor, Robert Graziano, Eric Crawford, and Eric VA Mid-Atlantic MIRECC Workgroup. “Risk factors for concurrent suicidal ideation and violent impulses in military veterans.” Psychol Assess 30, no. 4 (April 2018): 425–35. https://doi.org/10.1037/pas0000490.
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    • Mirzaalian, Hengameh, Lipeng Ning, Peter Savadjiev, Ofer Pasternak, Sylvain Bouix, Oleg Michailovich, Sarina Karmacharya, et al. “Multi-site harmonization of diffusion MRI data in a registration framework.” Brain Imaging Behav 12, no. 1 (February 2018): 284–95. https://doi.org/10.1007/s11682-016-9670-y.
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    • Sun, Delin, Sarah L. Davis, Courtney C. Haswell, Chelsea A. Swanson, Chelsea A. Mid-Atlantic MIRECC Workgroup, Kevin S. LaBar, John A. Fairbank, and Rajendra A. Morey. “Brain Structural Covariance Network Topology in Remitted Posttraumatic Stress Disorder.” Front Psychiatry 9 (2018): 90. https://doi.org/10.3389/fpsyt.2018.00090.
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    • Sheerin, C. M., K. J. Stratton, A. B. Amstadter, S. D. McDonald, J. C. Beckham, M. Brancu, P. S. Calhoun, et al. “Exploring resilience models in a sample of combat-exposed military service members and veterans: a comparison and commentary.” European Journal of Psychotraumatology 9, no. 1 (January 1, 2018). https://doi.org/10.1080/20008198.2018.1486121.
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    • Mason, Brittany L., Erin Van Enkevort, Francesca Filbey, Christine E. Marx, John Park, Alyson Nakamura, Prabha Sunderajan, and E Sherwood Brown. “Neurosteroid Levels in Patients With Bipolar Disorder and a History of Cannabis Use Disorders.” Journal of Clinical Psychopharmacology 37, no. 6 (December 2017): 684–88. https://doi.org/10.1097/jcp.0000000000000793.
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    • Morey, Rajendra A., Sarah L. Davis, Melanie E. Garrett, Courtney C. Haswell, Courtney C. Mid-Atlantic MIRECC Workgroup, Christine E. Marx, Jean C. Beckham, Gregory McCarthy, Michael A. Hauser, and Allison E. Ashley-Koch. “Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.” Transl Psychiatry 7, no. 11 (November 30, 2017): 1265. https://doi.org/10.1038/s41398-017-0021-6.
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    • Martindale, Sarah L., Leah V. Farrell-Carnahan, Christi S. Ulmer, Nathan A. Kimbrel, Scott D. McDonald, Jared A. Rowland, and Jared A. VA Mid-Atlantic MIRECC Registry Workgroup. “Sleep quality in returning veterans: The influence of mild traumatic brain injury.” Rehabil Psychol 62, no. 4 (November 2017): 563–70. https://doi.org/10.1037/rep0000159.
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    • Brancu, Mira, H Ryan Wagner, Rajendra A. Morey, Jean C. Beckham, Patrick S. Calhoun, Larry A. Tupler, Christine E. Marx, et al. “The Post-Deployment Mental Health (PDMH) study and repository: A multi-site study of US Afghanistan and Iraq era veterans.” Int J Methods Psychiatr Res 26, no. 3 (September 2017). https://doi.org/10.1002/mpr.1570.
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    • Roberge, E. M., D. M. Benedek, C. E. Marx, A. M. Rasmusson, and A. J. Lang. “Analysis of recruitment strategies: Enrolling veterans with PTSD into a clinical trial.” Military Psychology 29, no. 5 (September 1, 2017): 407–17. https://doi.org/10.1037/mil0000178.
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    • Naylor, Jennifer C., H. Ryan Wagner, Mira Brancu, Megan Shepherd-Banigan, Eric Elbogen, Michelle Kelley, Teresa Fecteau, et al. “Self-Reported Pain in Male and Female Iraq/Afghanistan-Era Veterans: Associations with Psychiatric Symptoms and Functioning.” Pain Med 18, no. 9 (September 1, 2017): 1658–67. https://doi.org/10.1093/pm/pnw308.
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    • Rasmusson, Ann M., Christine E. Marx, Sonia Jain, Gail M. Farfel, Julia Tsai, Xiaoying Sun, Thomas D. Geracioti, et al. “A randomized controlled trial of ganaxolone in posttraumatic stress disorder.” Psychopharmacology (Berl) 234, no. 15 (August 2017): 2245–57. https://doi.org/10.1007/s00213-017-4649-y.
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    • Rasmusson, Ann M., Christine E. Marx, Suzanne L. Pineles, Andrea Locci, Erica R. Scioli-Salter, Yael I. Nillni, Jennifer J. Liang, and Graziano Pinna. “Neuroactive steroids and PTSD treatment.” Neurosci Lett 649 (May 10, 2017): 156–63. https://doi.org/10.1016/j.neulet.2017.01.054.
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    • Servatius, Richard J., Justin D. Handy, Michael J. Doria, Catherine E. Myers, Christine E. Marx, Robert Lipsky, Nora Ko, Pelin Avcu, W Geoffrey Wright, and Jack W. Tsao. “Stress-Related Mental Health Symptoms in Coast Guard: Incidence, Vulnerability, and Neurocognitive Performance.” Front Psychol 8 (2017): 1513. https://doi.org/10.3389/fpsyg.2017.01513.
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    • Servatius, Richard J., Christine E. Marx, Swamini Sinha, Pelin Avcu, Jason D. Kilts, Jennifer C. Naylor, and Kevin C. H. Pang. “Brain and Serum Androsterone Is Elevated in Response to Stress in Rats with Mild Traumatic Brain Injury.” Frontiers in Neuroscience 10 (August 26, 2016). https://doi.org/10.3339/fnins.2016.00379.
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    • Mirzaalian, H., L. Ning, P. Savadjiev, O. Pasternak, S. Bouix, O. Michailovich, G. Grant, et al. “Inter-site and inter-scanner diffusion MRI data harmonization.” Neuroimage 135 (July 15, 2016): 311–23. https://doi.org/10.1016/j.neuroimage.2016.04.041.
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    • Schry, Amie R., Jean C. Beckham, Jean C. The Va Mid-Atlantic Mirecc Workgroup, and Patrick S. Calhoun. “Sexual revictimization among Iraq and Afghanistan war era veterans.” Psychiatry Res 240 (June 30, 2016): 406–11. https://doi.org/10.1016/j.psychres.2016.04.016.
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    • Servatius, Richard J., Christine E. Marx, Swamini Sinha, Pelin Avcu, Jason D. Kilts, Jennifer C. Naylor, and Kevin C. H. Pang. “Brain and Serum Androsterone Is Elevated in Response to Stress in Rats with Mild Traumatic Brain Injury.” Front Neurosci 10 (2016): 379. https://doi.org/10.3389/fnins.2016.00379.
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    • Naylor, Jennifer C., Jason D. Kilts, Jennifer L. Strauss, Steven T. Szabo, Charlotte E. Dunn, H Ryan Wagner, Robert M. Hamer, et al. “An exploratory pilot investigation of neurosteroids and self-reported pain in female Iraq/Afghanistan-era Veterans.” J Rehabil Res Dev 53, no. 4 (2016): 499–510. https://doi.org/10.1682/JRRD.2014.11.0294.
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    • Naylor, Jennifer C., Jason D. Kilts, Steven T. Szabo, Charlotte E. Dunn, Francis J. Keefe, Larry A. Tupler, Lawrence J. Shampine, et al. “Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.” Pain Med 17, no. 1 (January 2016): 25–32. https://doi.org/10.1111/pme.12860.
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    • Scioli-Salter, Erica, Daniel E. Forman, John D. Otis, Carlos Tun, Kelly Allsup, Christine E. Marx, Richard L. Hauger, et al. “Potential neurobiological benefits of exercise in chronic pain and posttraumatic stress disorder: Pilot study.” J Rehabil Res Dev 53, no. 1 (2016): 95–106. https://doi.org/10.1682/JRRD.2014.10.0267.
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    • Morey, R. A., J. E. Dunsmoor, C. C. Haswell, V. M. Brown, A. Vora, J. Weiner, D. Stjepanovic, H. R. Wagner, H. R. VA Mid-Atlantic MIRECC Workgroup, and K. S. LaBar. “Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.” Transl Psychiatry 5, no. 12 (December 15, 2015): e700. https://doi.org/10.1038/tp.2015.196.
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    • Schry, Amie R., Rachel Hibberd, H Ryan Wagner, Jessica A. Turchik, Nathan A. Kimbrel, Madrianne Wong, Eric E. Elbogen, Jennifer L. Strauss, Jennifer L. Veterans Affairs Mid-Atlantic Mental Illness Research, Education and Clinical Center Workgroup, and Mira Brancu. “Functional correlates of military sexual assault in male veterans.” Psychol Serv 12, no. 4 (November 2015): 384–93. https://doi.org/10.1037/ser0000053.
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    • Ben Dor, Rivka, Christine E. Marx, Lawrence J. Shampine, David R. Rubinow, and Peter J. Schmidt. “Erratum to: DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.” Psychopharmacology (Berl) 232, no. 19 (October 2015): 3683. https://doi.org/10.1007/s00213-015-4046-3.
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    • Kimbrel, Nathan A., Melanie E. Garrett, Michelle F. Dennis, Yutao Liu, Ilyas Patanam, Va Mid-Atlantic Mirecc Workgroup, Allison E. Ashley-Koch, Michael A. Hauser, and Jean C. Beckham. “Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.” Psychiatry Res 229, no. 1–2 (September 30, 2015): 326–31. https://doi.org/10.1016/j.psychres.2015.07.002.
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    • Ben Dor, Rivka, Christine E. Marx, Lawrence J. Shampine, David R. Rubinow, and Peter J. Schmidt. “DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.” Psychopharmacology (Berl) 232, no. 18 (September 2015): 3375–83. https://doi.org/10.1007/s00213-015-3991-1.
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    • Kelley, Michelle L., Mira Brancu, Allison T. Robbins, Gabrielle M. D’Lima, Jennifer L. Strauss, John F. Curry, John A. Fairbank, Jennifer Runnals, and Jennifer VA Mid-Atlantic MIRECC Women Veterans Workgroup, VA Mid-Atlantic MIRECC Workgroup. “Drug use and childhood-, military- and post-military trauma exposure among women and men veterans.” Drug Alcohol Depend 152 (July 1, 2015): 201–8. https://doi.org/10.1016/j.drugalcdep.2015.03.038.
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    • Naylor, Jennifer C., Jason D. Kilts, Daniel W. Bradford, Jennifer L. Strauss, Bruce P. Capehart, Steven T. Szabo, Karen D. Smith, et al. “A pilot randomized placebo-controlled trial of adjunctive aripiprazole for chronic PTSD in US military Veterans resistant to antidepressant treatment.” Int Clin Psychopharmacol 30, no. 3 (May 2015): 167–74. https://doi.org/10.1097/YIC.0000000000000061.
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    • Youssef, Nagy A., Daniel W. Bradford, Jason D. Kilts, Steven T. Szabo, Jennifer C. Naylor, Trina B. Allen, Jennifer L. Strauss, et al. “Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.” Crisis 36, no. 1 (2015): 46–54. https://doi.org/10.1027/0227-5910/a000280.
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    • Kimbrel, Nathan A., Patrick S. Calhoun, Eric B. Elbogen, Mira Brancu, Mira VA Mid-Atlantic MIRECC Registry Workgroup, and Jean C. Beckham. “The factor structure of psychiatric comorbidity among Iraq/Afghanistan-era veterans and its relationship to violence, incarceration, suicide attempts, and suicidality.” Psychiatry Res 220, no. 1–2 (December 15, 2014): 397–403. https://doi.org/10.1016/j.psychres.2014.07.064.
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    • Gentes, Emily L., Paul A. Dennis, Nathan A. Kimbrel, Michelle B. Rissling, Jean C. Beckham, Jean C. VA Mid-Atlantic MIRECC Workgroup, and Patrick S. Calhoun. “DSM-5 posttraumatic stress disorder: factor structure and rates of diagnosis.” J Psychiatr Res 59 (December 2014): 60–67. https://doi.org/10.1016/j.jpsychires.2014.08.014.
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    • Brown, E Sherwood, John Park, Christine E. Marx, Linda S. Hynan, Claire Gardner, Domingo Davila, Alyson Nakamura, Prabha Sunderajan, Alexander Lo, and Traci Holmes. “A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression.” Neuropsychopharmacology 39, no. 12 (November 2014): 2867–73. https://doi.org/10.1038/npp.2014.138.
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    • Guffanti, G., A. E. Ashley-Koch, A. L. Roberts, M. E. Garrett, N. Solovieff, A. Ratanatharathorn, I. De Vivo, et al. “No association between RORA polymorphisms and PTSD in two independent samples.” Mol Psychiatry 19, no. 10 (October 2014): 1056–57. https://doi.org/10.1038/mp.2014.19.
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    • Marx, Christine E., Jimmy Lee, Mythily Subramaniam, Attilio Rapisarda, Dianne C. T. Bautista, Edwin Chan, Jason D. Kilts, et al. “Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia.” Psychopharmacology (Berl) 231, no. 17 (September 2014): 3647–62. https://doi.org/10.1007/s00213-014-3673-4.
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    • Naylor, Jennifer C., Jeffery J. Borckardt, Christine E. Marx, Robert M. Hamer, Sarah Fredrich, Scott T. Reeves, and Mark S. George. “Cathodal and anodal left prefrontal tDCS and the perception of control over pain.” Clin J Pain 30, no. 8 (August 2014): 693–700. https://doi.org/10.1097/AJP.0000000000000025.
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    • Sripada, Rebecca K., Robert C. Welsh, Christine E. Marx, and Israel Liberzon. “The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting-state amygdala connectivity.” Hum Brain Mapp 35, no. 7 (July 2014): 3249–61. https://doi.org/10.1002/hbm.22399.
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    • Brancu, Mira, Nivonne L. Thompson, Jean C. Beckham, Kimberly T. Green, Patrick S. Calhoun, Eric B. Elbogen, Allison T. Robbins, John A. Fairbank, John A. VA Mid-Atlantic MIRECC Registry Workgroup, and H Ryan Wagner. “The impact of social support on psychological distress for U.S. Afghanistan/Iraq era veterans with PTSD and other psychiatric diagnoses.” Psychiatry Res 217, no. 1–2 (June 30, 2014): 86–92. https://doi.org/10.1016/j.psychres.2014.02.025.
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    • Szabo, Steven T., Jason D. Kilts, Jennifer C. Naylor, Nagy A. Youssef, Jennifer L. Strauss, Rajendra A. Morey, Mira Brancu, et al. “Amino acids as biomarker candidates for suicidality in male OEF/OIF Veterans: relevance to NMDA receptor modulation and nitric oxide signaling.” Mil Med 179, no. 5 (May 2014): 486–91. https://doi.org/10.7205/MILMED-D-13-00337.
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    • Diaz-Arrastia, Ramon, Patrick M. Kochanek, Peter Bergold, Kimbra Kenney, Christine E. Marx, Col Jamie B. Grimes, LTC Yince Loh, et al. “Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup.” J Neurotrauma 31, no. 2 (January 15, 2014): 135–58. https://doi.org/10.1089/neu.2013.3019.
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    • Brown, Vanessa M., Kevin S. LaBar, Courtney C. Haswell, Andrea L. Gold, Andrea L. Mid-Atlantic MIRECC Workgroup, Gregory McCarthy, and Rajendra A. Morey. “Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder.” Neuropsychopharmacology 39, no. 2 (January 2014): 351–59. https://doi.org/10.1038/npp.2013.197.
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    • Morey, Rajendra A., Courtney C. Haswell, Elizabeth S. Selgrade, Dino Massoglia, Chunlei Liu, Jonathan Weiner, Christine E. Marx, Christine E. MIRECC Work Group, Ibolja Cernak, and Gregory McCarthy. “Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.” Hum Brain Mapp 34, no. 11 (November 2013): 2986–99. https://doi.org/10.1002/hbm.22117.
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    • Sripada, Rebecca K., Christine E. Marx, Anthony P. King, Nirmala Rajaram, Sarah N. Garfinkel, James L. Abelson, and Israel Liberzon. “DHEA enhances emotion regulation neurocircuits and modulates memory for emotional stimuli.” Neuropsychopharmacology 38, no. 9 (August 2013): 1798–1807. https://doi.org/10.1038/npp.2013.79.
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    • Strauss, Jennifer L., Jennifer B. Zervakis, Karen M. Stechuchak, Maren K. Olsen, Jeffrey Swanson, Marvin S. Swartz, Morris Weinberger, et al. “Adverse impact of coercive treatments on psychiatric inpatients' satisfaction with care.” Community Ment Health J 49, no. 4 (August 2013): 457–65. https://doi.org/10.1007/s10597-012-9539-5.
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    • Swinkels, Cindy M., Christi S. Ulmer, Jean C. Beckham, Natalie Buse, and Patrick S. Calhoun. “The Association of Sleep Duration, Mental Health, and Health Risk Behaviors among U.S. Afghanistan/Iraq Era Veterans.” Sleep 36, no. 7 (July 2013): 1019–25. https://doi.org/10.5665/sleep.2800.
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    • Sripada, Rebecca K., Christine E. Marx, Anthony P. King, Jessica C. Rampton, S Shaun Ho, and Israel Liberzon. “Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits.” Biol Psychiatry 73, no. 11 (June 1, 2013): 1045–53. https://doi.org/10.1016/j.biopsych.2012.12.008.
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    • Naylor, Jennifer C., Trygve R. Dolber, Jennifer L. Strauss, Jason D. Kilts, Timothy J. Strauman, Daniel W. Bradford, Steven T. Szabo, et al. “A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.” Psychiatry Res 206, no. 2–3 (April 30, 2013): 318–20. https://doi.org/10.1016/j.psychres.2012.11.008.
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    • Youssef, Nagy A., Christine E. Marx, Daniel W. Bradford, Sandra Zinn, Michael A. Hertzberg, Jason D. Kilts, Jennifer C. Naylor, Marian I. Butterfield, and Jennifer L. Strauss. “An open-label pilot study of aripiprazole for male and female veterans with chronic post-traumatic stress disorder who respond suboptimally to antidepressants.” Int Clin Psychopharmacol 27, no. 4 (July 2012): 191–96. https://doi.org/10.1097/YIC.0b013e328352ef4e.
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    • Wong, Peiyan, Cecilia Chin Roei Chang, Christine E. Marx, Marc G. Caron, William C. Wetsel, and Xiaodong Zhang. “Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.” Plos One 7, no. 12 (2012): e51455. https://doi.org/10.1371/journal.pone.0051455.
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    • Chong, Siow-Ann, Alastair Campbell, Michael Chee, Jianjun Liu, Christine Marx, Patrick McGorry, Mythily Subramaniam, Alison Yung, and Richard S. E. Keefe. “The Singapore flagship programme in translational and clinical research in psychosis.” Early Interv Psychiatry 5, no. 4 (November 2011): 290–300. https://doi.org/10.1111/j.1751-7893.2011.00304.x.
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    • Marx, C. E., D. W. Bradford, R. M. Hamer, J. C. Naylor, T. B. Allen, J. A. Lieberman, J. L. Strauss, and J. D. Kilts. “Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence.” Neuroscience 191 (September 15, 2011): 78–90. https://doi.org/10.1016/j.neuroscience.2011.06.076.
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    • Youssef, Nagy A., Margaret Ege, Sohair S. Angly, Jennifer L. Strauss, and Christine E. Marx. “Is obstructive sleep apnea associated with ADHD?” Ann Clin Psychiatry 23, no. 3 (August 2011): 213–24.
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    • Strauss, Jennifer L., Christine E. Marx, Julie C. Weitlauf, Karen M. Stechuchak, Kristy Straits-Troster, Ayaba W. Worjoloh, Christina B. Sherrod, Maren K. Olsen, Marian I. Butterfield, and Patrick S. Calhoun. “Is military sexual trauma associated with trading sex among women veterans seeking outpatient mental health care?” J Trauma Dissociation 12, no. 3 (2011): 290–304. https://doi.org/10.1080/15299732.2011.551509.
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    • Strauss, J. L., V. S. Guerra, C. E. Marx, A. Meade Eggleston, and P. S. Calhoun. “Adherence and psychotherapy,” December 1, 2010, 215–40. https://doi.org/10.1007/978-1-4419-5866-2_9.
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    • Kilts, Jason D., Larry A. Tupler, Francis J. Keefe, Victoria M. Payne, Robert M. Hamer, Jennifer C. Naylor, Rohana P. Calnaido, et al. “Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.” Pain Med 11, no. 10 (October 2010): 1469–76. https://doi.org/10.1111/j.1526-4637.2010.00927.x.
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    • Elbogen, Eric B., H Ryan Wagner, Sara R. Fuller, Patrick S. Calhoun, Patricia M. Kinneer, Patricia M. Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and Jean C. Beckham. “Correlates of anger and hostility in Iraq and Afghanistan war veterans.” Am J Psychiatry 167, no. 9 (September 2010): 1051–58. https://doi.org/10.1176/appi.ajp.2010.09050739.
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    • Naylor, Jennifer C., Jason D. Kilts, Christine M. Hulette, David C. Steffens, Dan G. Blazer, John F. Ervin, Jennifer L. Strauss, et al. “Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.” Biochim Biophys Acta 1801, no. 8 (August 2010): 951–59. https://doi.org/10.1016/j.bbalip.2010.05.006.
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    • Strauss, J. L., P. S. Calhoun, and C. E. Marx. “Guided imagery as a therapeutic tool in post-traumatic stress disorder,” December 1, 2009, 363–73. https://doi.org/10.1007/978-1-60327-329-9_17.
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    • Chong, Siow-Ann, Yuen Yeng Ong, Mythily Subramaniam, Edimansyah Abdin, Christine E. Marx, and Alastair Vincent Campbell. “An assessment of the understanding and motivations of patients with schizophrenia about participating in a clinical trial.” Contemp Clin Trials 30, no. 5 (September 2009): 446–50. https://doi.org/10.1016/j.cct.2009.04.006.
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    • Marx, Christine E., Richard S. E. Keefe, Robert W. Buchanan, Robert M. Hamer, Jason D. Kilts, Daniel W. Bradford, Jennifer L. Strauss, et al. “Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.” Neuropsychopharmacology 34, no. 8 (July 2009): 1885–1903. https://doi.org/10.1038/npp.2009.26.
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    • Dedert, Eric A., Kimberly T. Green, Patrick S. Calhoun, Ruth Yoash-Gantz, Katherine H. Taber, Marinell Miller Mumford, Larry A. Tupler, et al. “Association of trauma exposure with psychiatric morbidity in military veterans who have served since September 11, 2001.” J Psychiatr Res 43, no. 9 (June 2009): 830–36. https://doi.org/10.1016/j.jpsychires.2009.01.004.
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    • Marx, Christine E., R. S. Keefe, V. M. Payne, J. D. Kilts, J. L. Strauss, J. C. Naylor, R. M. Hamer, et al. “NEUROSTEROIDS AS NOVEL THERAPEUTIC AGENTS IN SCHIZOPHRENIA AND PTSD.” Schizophrenia Bulletin 35 (March 1, 2009): 368–368.
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    • Porcu, Patrizia, Todd K. O’Buckley, Sarah E. Alward, Christine E. Marx, Lawrence J. Shampine, Susan S. Girdler, and A Leslie Morrow. “Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.” Steroids 74, no. 4–5 (2009): 463–73. https://doi.org/10.1016/j.steroids.2008.12.015.
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    • Lieberman, J. A., F. P. Bymaster, H. Y. Meltzer, A. Y. Deutch, G. E. Duncan, C. E. Marx, J. R. Aprille, et al. “Antipsychotic drugs: Comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection (Pharmacological Reviews (2002) 60, (358-403)).” Pharmacological Reviews 60, no. 4 (December 1, 2008): 582.
    • Payne, V. M., J. D. Kilts, J. C. Naylor, J. L. Strauss, P. S. Calhoun, R. D. Madison, and C. E. Marx. “Allopregnanolone and pregnenolone alterations following pharmacological agents in rodents and clinic populations,” December 1, 2008, 369–83. https://doi.org/10.1007/978-1-4020-6854-6_18.
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    • Lieberman, Jeffrey A., Frank P. Bymaster, Herbert Y. Meltzer, Ariel Y. Deutch, Gary E. Duncan, Christine E. Marx, June R. Aprille, et al. “Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection.” Pharmacol Rev 60, no. 3 (September 2008): 358–403. https://doi.org/10.1124/pr.107.00107.
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    • Bradford, Daniel W., Mimi M. Kim, Loretta E. Braxton, Christine E. Marx, Marian Butterfield, and Eric B. Elbogen. “Access to medical care among persons with psychotic and major affective disorders.” Psychiatr Serv 59, no. 8 (August 2008): 847–52. https://doi.org/10.1176/ps.2008.59.8.847.
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    • Naylor, Jennifer C., Christine M. Hulette, David C. Steffens, Lawrence J. Shampine, John F. Ervin, Victoria M. Payne, Mark W. Massing, et al. “Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.” J Clin Endocrinol Metab 93, no. 8 (August 2008): 3173–78. https://doi.org/10.1210/jc.2007-1229.
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    • Marx, Christine E., Peixiong Yuan, Jason D. Kilts, Roger D. Madison, Lawrence J. Shampine, and Husseini K. Manji. “Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice.” Int J Neuropsychopharmacol 11, no. 4 (June 2008): 547–52. https://doi.org/10.1017/S1461145708008444.
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    • McDonald, Scott D., Jean C. Beckham, Rajendra Morey, Christine Marx, Larry A. Tupler, and Patrick S. Calhoun. “Factorial invariance of posttraumatic stress disorder symptoms across three veteran samples.” J Trauma Stress 21, no. 3 (June 2008): 309–17. https://doi.org/10.1002/jts.20344.
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    • Wang, Chunsheng, Christine E. Marx, A Leslie Morrow, Wilkie A. Wilson, and Scott D. Moore. “Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors.” Neurosci Lett 415, no. 2 (March 26, 2007): 118–23. https://doi.org/10.1016/j.neulet.2007.01.004.
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    • Calhoun, Patrick S., Karen M. Stechuchak, Jennifer Strauss, Hayden B. Bosworth, Christine E. Marx, and Marian I. Butterfield. “Interpersonal trauma, war zone exposure, and posttraumatic stress disorder among veterans with schizophrenia.” Schizophr Res 91, no. 1–3 (March 2007): 210–16. https://doi.org/10.1016/j.schres.2006.12.011.
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    • Marx, C. “Sexuality and commitment.” Sexologies 16, no. 1 (January 1, 2007): 53–59. https://doi.org/10.1016/j.sexol.2006.07.006.
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    • Massing, Mark W., Judyta Misiurek, Srinivas R. Chadaram, Christine E. Marx, and Roger Madison. “New developments in proteomics.” N C Med J 68, no. 2 (2007): 119–22.
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    • Marx, Christine E., William T. Trost, Lawrence J. Shampine, Robert D. Stevens, Christine M. Hulette, David C. Steffens, John F. Ervin, et al. “The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.” Biol Psychiatry 60, no. 12 (December 15, 2006): 1287–94. https://doi.org/10.1016/j.biopsych.2006.06.017.
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    • Marx, Christine E., Lawrence J. Shampine, Gary E. Duncan, Margaret J. VanDoren, A Chistina Grobin, Mark W. Massing, Roger D. Madison, et al. “Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy?” Pharmacol Biochem Behav 84, no. 4 (August 2006): 598–608. https://doi.org/10.1016/j.pbb.2006.07.026.
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    • Marx, Christine E., Lawrence J. Shampine, Rahul T. Khisti, William T. Trost, Daniel W. Bradford, A Chistina Grobin, Mark W. Massing, et al. “Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions.” Pharmacol Biochem Behav 84, no. 4 (August 2006): 609–17. https://doi.org/10.1016/j.pbb.2006.07.032.
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    • Marx, Christine E., Robert D. Stevens, Lawrence J. Shampine, Veska Uzunova, William T. Trost, Marian I. Butterfield, Mark W. Massing, Robert M. Hamer, A Leslie Morrow, and Jeffrey A. Lieberman. “Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics.” Neuropsychopharmacology 31, no. 6 (June 2006): 1249–63. https://doi.org/10.1038/sj.npp.1300952.
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    • Marx, Christine E., William T. Trost, Lawrence Shampine, Frederique M. Behm, Louis A. Giordano, Mark W. Massing, and Jed E. Rose. “Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers.” Psychopharmacology (Berl) 186, no. 3 (June 2006): 462–72. https://doi.org/10.1007/s00213-005-0226-x.
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    • Pierucci-Lagha, Amira, Jonathan Covault, Richard Feinn, Rahul T. Khisti, A Leslie Morrow, Christine E. Marx, Lawrence J. Shampine, and Henry R. Kranzler. “Subjective effects and changes in steroid hormone concentrations in humans following acute consumption of alcohol.” Psychopharmacology (Berl) 186, no. 3 (June 2006): 451–61. https://doi.org/10.1007/s00213-005-0231-0.
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    • Strauss, J. L., P. S. Calhoun, C. E. Marx, K. M. Stechuchak, E. Z. Oddone, M. S. Swartz, and M. I. Butterfield. “Comorbid posttraumatic stress disorder is associated with suicidality in male veterans with schizophrenia or schizoaffective disorder.” Schizophr Res 84, no. 1 (May 2006): 165–69. https://doi.org/10.1016/j.schres.2006.02.010.
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    • Butterfield, Marian I., Karen M. Stechuchak, Kathryn M. Connor, Jonathan R. T. Davidson, Chungsheng Wang, Courteney L. MacKuen, Anne M. Pearlstein, and Christine E. Marx. “Neuroactive steroids and suicidality in posttraumatic stress disorder.” Am J Psychiatry 162, no. 2 (February 2005): 380–82. https://doi.org/10.1176/appi.ajp.162.2.380.
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    • Marx, C. E., A. C. Grobin, A. Y. Deutch, and J. A. Lieberman. “Chapter 3.5 Atypical antipsychotic drugs and stress” 15, no. PART 2 (January 1, 2005): 301–13. https://doi.org/10.1016/S0921-0709(05)80061-6.
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    • Miyamoto, S., G. E. Duncan, C. E. Marx, and J. A. Lieberman. “Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs.” Mol Psychiatry 10, no. 1 (January 2005): 79–104. https://doi.org/10.1038/sj.mp.4001556.
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    • Marx, Christine E., Margaret J. VanDoren, Gary E. Duncan, Jeffrey A. Lieberman, and A Leslie Morrow. “Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents.” Neuropsychopharmacology 28, no. 1 (January 2003): 1–13. https://doi.org/10.1038/sj.npp.1300015.
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    • Butterfield, Marian I., Mary Becker, and Christine E. Marx. “Post-traumatic stress disorder in women: current concepts and treatments.” Curr Psychiatry Rep 4, no. 6 (December 2002): 474–86. https://doi.org/10.1007/s11920-002-0076-8.
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    • Watson, Lea C., and Christine E. Marx. “New onset of neuropsychiatric symptoms in the elderly: possible primary hyperparathyroidism.” Psychosomatics 43, no. 5 (2002): 413–17. https://doi.org/10.1176/appi.psy.43.5.413.
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    • Marx, C. E., L. F. Jarskog, J. M. Lauder, J. A. Lieberman, and J. H. Gilmore. “Cytokine effects on cortical neuron MAP-2 immunoreactivity: implications for schizophrenia.” Biol Psychiatry 50, no. 10 (November 15, 2001): 743–49. https://doi.org/10.1016/s0006-3223(01)01209-4.
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    • Marx, C. E., E. McIntosh, W. H. Wilson, and J. P. McEvoy. “Mecamylamine increases cigarette smoking in psychiatric patients.” J Clin Psychopharmacol 20, no. 6 (December 2000): 706–7. https://doi.org/10.1097/00004714-200012000-00023.
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    • Marx, C. E., L. F. Jarskog, J. M. Lauder, J. H. Gilmore, J. A. Lieberman, and A. L. Morrow. “Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia.” Brain Res 871, no. 1 (July 14, 2000): 104–12. https://doi.org/10.1016/s0006-8993(00)02452-5.
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    • Marx, C. E., G. E. Duncan, J. H. Gilmore, J. A. Lieberman, and A. L. Morrow. “Olanzapine increases allopregnanolone in the rat cerebral cortex.” Biol Psychiatry 47, no. 11 (June 1, 2000): 1000–1004. https://doi.org/10.1016/s0006-3223(99)00305-4.
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    • Marx, C. E., B. J. Vance, L. F. Jarskog, N. C. Chescheir, and J. H. Gilmore. “Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 levels in human amniotic fluid.” Am J Obstet Gynecol 181, no. 5 Pt 1 (November 1999): 1225–30. https://doi.org/10.1016/s0002-9378(99)70113-4.
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    • Marx, C. E., and J. A. Lieberman. “Psychoneuroendocrinology of schizophrenia.” Psychiatr Clin North Am 21, no. 2 (June 1998): 413–34. https://doi.org/10.1016/s0193-953x(05)70013-7.
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    • Marx, C. E., K. Fan, A. J. Morris, M. L. Wilson, A. Damiani, and M. P. Weinstein. “Laboratory and clinical evaluation of Mycobacterium xenopi isolates.” Diagn Microbiol Infect Dis 21, no. 4 (April 1995): 195–202. https://doi.org/10.1016/0732-8893(95)00039-d.
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    • Morris, A. J., S. J. Wilson, C. E. Marx, M. L. Wilson, S. Mirrett, and L. B. Reller. “Clinical impact of bacteria and fungi recovered only from broth cultures.” J Clin Microbiol 33, no. 1 (January 1995): 161–65. https://doi.org/10.1128/jcm.33.1.161-165.1995.
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    • Marx, C. E., A. Morris, M. L. Wilson, and L. B. Reller. “Fecal leukocytes in stool specimens submitted for Clostridium difficile toxin assay.” Diagn Microbiol Infect Dis 16, no. 4 (1993): 313–15. https://doi.org/10.1016/0732-8893(93)90081-h.
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  • Book Sections

    • Marx, C. E., J. C. Naylor, J. D. Kilts, C. E. Dunn, L. A. Tupler, S. T. Szabo, B. P. Capehart, R. A. Morey, L. J. Shampine, and S. K. Acheson. “Neurosteroids and traumatic brain injury translating biomarkers to therapeutics; overview and pilot investigations in Iraq and Afghanistan era veterans.” In Translational Research in Traumatic Brain Injury, 145–61, 2016.
    • Massing, M. W., G. A. Robinson, C. E. Marx, O. Alzate, and R. D. Madison. “Applications of proteomics to nerve regeneration research.” In Neuroproteomics, 289–313, 2009.

  • Conference Papers

    • Morey, Rajendra A., Courtney C. Haswell, Wei Li, Shannon K. Bealll, Cassidy R. Fox, Christine E. Marx, and Chunlei Liu. “Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility Mapping.” In Biological Psychiatry, 77:40S-40S. ELSEVIER SCIENCE INC, 2015.
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    • Marx, Christine E. “Neurosteroids as Novel Therapeutics and Biomarker Candidates in Schizophrenia and PTSD.” In Neuropsychopharmacology, 38:S37–38. NATURE PUBLISHING GROUP, 2013.
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    • Wong, Peiyan, Cecilia Chin Roei Chang, Christine E. Marx, Marc G. Caron, William C. Wetsel, and Xiaodong Zhang. “Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice.” In Biological Psychiatry, 73:115S-116S. ELSEVIER SCIENCE INC, 2013.
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    • Sripada, Rebecca K., Christine E. Marx, Anthony P. King, Jessica Rampton, Shaun Ho, and Israel Liberzon. “Neuroactive Steroids Enhance Activation of Emotion Regulation Brain Circuits.” In Biological Psychiatry, 71:177S-178S. ELSEVIER SCIENCE INC, 2012.
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    • Ben Dor, Rivi, Christine E. Marx, David R. Rubinow, and Peter J. Schmidt. “Plasma Levels of the Neurosteroid Androsterone Increase after DHEA Therapy and Are Associated with Changes in Mood and Sexual Functioning in a Sexually Dimorphic Manner.” In Endocrine Reviews, Vol. 31. ENDOCRINE SOC, 2010.
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    • Marx, Christine E. “Proof-of-Concept Randomized Controlled Trial with Pregnenolone in Mild Traumatic Brain Injury.” In Biological Psychiatry, 67:22S-22S. ELSEVIER SCIENCE INC, 2010.
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    • Eggleston, A. M., S. D. McDonald, P. S. Calhoun, J. C. Beckham, K. Straits-Troster, C. E. Marx, and R. A. Morey. “Alcohol use among OEF-OIF veterans with and without posttraumatic stress disorder.” In Alcoholism Clinical and Experimental Research, 32:75A-75A. BLACKWELL PUBLISHING, 2008.
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    • Nayllor, Jennifer C., Victoria M. Payne, Patrick S. Calhoun, Rajendra A. Morey, Jean C. Beckham, Larry A. Tupler, Gary E. Duncan, Lawrence J. Shampine, Jason D. Kilts, and Christine E. Marx. “L-serine predicts self-reported pain in female OEF/OIF veterans.” In Biological Psychiatry, 63:218S-218S. ELSEVIER SCIENCE INC, 2008.
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    • Marx, Christine E., Richard S. Keefe, Linda A. Leimone, Robert M. Hamer, Daniel W. Bradford, Lawrence Dunn, Victoria M. Payne, et al. “Proof-of-concept trial with the neurosterold pregnenolone targeting neurocognitive and negative symptoms in schizophrenia.” In Biological Psychiatry, 61:13S-13S. ELSEVIER SCIENCE INC, 2007.
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    • Naylor, Jennifer C., Victoria M. Payne, Christine M. Hulette, Lawrence J. Shampine, Robert D. Stevens, John F. Ervin, Mark W. Massing, et al. “Cerebrospinal fluid DHEA levels are elevated in Alzheimer's disease, related to neuropathological disease stage, and correlated with brain DHEA levels.” In Biological Psychiatry, 61:142S-142S. ELSEVIER SCIENCE INC, 2007.
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    • Payne, Victoria M., Rajendra A. Morey, Robert M. Hamer, Larry A. Tupler, Patrick S. Calhoun, Jean C. Beckham, Lawrence J. Shampine, et al. “Neuroactive steroids are related to psychiatric symptoms in veterans returning from iraq and Afghanistan.” In Biological Psychiatry, 61:130S-131S. ELSEVIER SCIENCE INC, 2007.
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    • Bradford, D. W., L. J. Shampine, V. P. Harris, J. C. Naylor, M. W. Massing, J. A. Lieberman, A. L. Morrow, and C. E. Marx. “Pregnenolone reductions in parietal cortex are associated with suicide in patients with schizophrenia.” In Schizophrenia Bulletin, 33:308–308. OXFORD UNIV PRESS, 2007.
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    • Marx, C. E., L. J. Shampine, G. E. Duncan, M. J. VanDoren, A. C. Grobin, M. W. Massing, R. D. Madison, et al. “Clozapine increases the neurosteroid pregnenolone in rat hippocampus, cerebral cortex, and serum: Relevance to superior efficacy?” In Schizophrenia Bulletin, 33:319–319. OXFORD UNIV PRESS, 2007.
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    • Bradford, Daniel W., Lawrence J. Shampine, Victoria P. Harris, Jennifer C. Naylor, Mark W. Massing, Jeffrey A. Lieberman, A. L. Morrow, and Christine E. Marx. “Pregnenolone alterations in parietat cortex are associated with death by suicide in patients with schizophrenia.” In Neuropsychopharmacology, 31:S118–19. NATURE PUBLISHING GROUP, 2006.
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    • Marx, Christine E., Lawrence J. Shampine, Gary E. Duncan, Margaret J. VanDoren, A. C. Grobin, Mark W. Massing, Roger D. Madison, et al. “Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: Candidate mechanism for superior efficacy?” In Neuropsychopharmacology, 31:S117–S117. NATURE PUBLISHING GROUP, 2006.
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    • Marx, C. E. “Neurosteroids as candidate modulators of pathophysiology in Alzheimer's disease and nicotine dependence.” In Biological Psychiatry, 59:193S-193S. ELSEVIER SCIENCE INC, 2006.
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    • Marx, C. E., D. C. Steffens, D. G. Blazer, M. I. Butterfield, C. Hulette, J. Ervin, J. A. Lieberman, and L. J. Shampine. “Deficit in the GABAergic neuroactive steroid allopregnanolone in Alzheimer's dementia and relevance to neuropathological disease stage: Investigations in temporal cortex.” In Neuropsychopharmacology, 30:S79–S79. NATURE PUBLISHING GROUP, 2005.
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    • Marx, C. E. “Neuroactive steroids in schizophrenia, PTSD, and Alzheimer's disease: Relevance to pathophysiology and treatment.” In Biological Psychiatry, 57:70S-70S. ELSEVIER SCIENCE INC, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, A. L. Morrow, V. Uzunova, T. T. William, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in posterior cingulate and parietal cortex in subjects with schizophrenia and bipolar disorder: Potential gender specificity.” In Biological Psychiatry, 57:6S-6S. ELSEVIER SCIENCE INC, 2005.
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    • Marx, C. E., P. X. Yuan, L. J. Shampine, and H. K. Manji. “Neuroactive steroids, mood stabilizers, and neuroplasticity: Alterations following lithium and changes in Bcl-2 knockout mice.” In Biological Psychiatry, 57:205S-205S. ELSEVIER SCIENCE INC, 2005.
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    • Trost, W. T., L. J. Shampine, C. Hulette, D. C. Steffens, J. A. Lieberman, D. G. Blazer, and C. E. Marx. “Neuroactive steroids and neurodegenerative disorders: Investigations in subjects with Alzheimer's and relevance to neuropathological disease stage.” In Biological Psychiatry, 57:204S-205S. ELSEVIER SCIENCE INC, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, A. L. Morrow, V. Uzunova, W. T. Trost, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in schizophrenia and bipolar disorder: Negative ion chemical ionization gas chromatography/mass spectrometry investigations in posterior cingulate and parietal cortex.” In Schizophrenia Bulletin, 31:253–253. OXFORD UNIV PRESS, 2005.
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    • Trost, W. T., R. Khisti, L. J. Shampine, J. A. Lieberman, G. Parke, A. L. Morrow, and C. E. Marx. “Olanzapine and fluoxetine effects on hippocampal pregnenolone and peripheral deoxycorticosterone: Relevance to therapeutic efficacy.” In Schizophrenia Bulletin, 31:313–313. OXFORD UNIV PRESS, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, W. T. Trost, A. L. Morrow, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in schizophrenia and bipolar disorder: A negative ion chemical ionization gas chromatography/mass spectrometry investigation in posterior cingulate.” In Neuropsychopharmacology, 29:S172–73. NATURE PUBLISHING GROUP, 2004.
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    • Marx, C. E., W. T. Trost, F. M. Behm, M. W. Massing, M. I. Butterfield, and J. E. Rose. “The neuroactive steroid dehydroepiandrosterone sulfate (DHEAS) predicts nicotine dependence severity.” In Neuropsychopharmacology, 29:S173–S173. NATURE PUBLISHING GROUP, 2004.
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    • Trost, W. T., L. J. Shampine, C. Hulette, D. C. Steffens, J. A. Lieberman, D. G. Blazer, and C. E. Marx. “Neuroactive steroids in Alzheimer's disease: Investigations in prefrontal cortex.” In Neuropsychopharmacology, 29:S130–31. NATURE PUBLISHING GROUP, 2004.
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    • Marx, C. E., W. T. Trost, L. J. Shampine, J. A. Lieberman, A. L. Morrow, and J. H. Thakore. “Neuroactive steroids in schizophrenia: Relevance to symptoms and therapeutics.” In Biological Psychiatry, 55:171S-172S. ELSEVIER SCIENCE INC, 2004.
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    • Wang, C. J., S. D. Moore, A. L. Morrow, J. A. Lieberman, W. A. Wilson, and C. E. Marx. “Neurosteroid modulation of GABAergic neurotransmission in the central amygdala.” In Schizophrenia Research, 60:263–263. ELSEVIER SCIENCE BV, 2003.
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    • Marx, C. E., M. L. Barbaccia, A. Guidotti, R. Rupprecht, and A. L. Morrow. “Neurosteroids and pharmacological treatment strategies in schizophrenia, depression, and anxiety disorders.” In Biological Psychiatry, 51:94S-94S. ELSEVIER SCIENCE INC, 2002.
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