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Christine Elizabeth Marx

Professor of Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
Box 3862 Med Ctr, DUMC, Durham, NC
VA Medical Ctr 116 A, 508 Fulton St, Durham, NC

Selected Grants


Duke University Psychiatry Physician-Scientist Residency Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

VA Research Service Agreement (Doug Williamson)

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2023 - 2028

Novel Intervention for Chronic Complex TBI in OEF/OIF/OND Veterans

ResearchPrincipal Investigator · Awarded by Department of Defense · 2022 - 2026

Allopregnanolone in post-stroke depression

ResearchCo Investigator · Awarded by American Heart Association · 2024 - 2026

A Neurosteroid Intervention for Menopausal And Perimenopausal Depression

ResearchPrincipal Investigator · Awarded by University of Texas Southwestern Medical Center · 2023 - 2025

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

VA Research Service Agreement (Doug Williamson)

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2022 - 2023

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

ResearchPrincipal Investigator · Awarded by University of Texas - Southwestern · 2018 - 2023

VA Research Service Agreement (Doug Williamson)

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2021 - 2022

IPA - Susan Helene O'Loughlin

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2021 - 2022

VA Research Service Agreement (Doug Williamson)

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2020 - 2021

IPA - Brian Thomas Cuffe

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2019 - 2021

IPA - Lawrence Shampine

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2019 - 2021

IPA - Patricia Resick

ResearchPrincipal Investigator · Awarded by Veterans Affairs Boston Healthcare System · 2020 - 2020

IPA - Jason Kilts

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2019 - 2020

IPA - Larry Allen Tupler

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2018 - 2020

IPA - Rachel Phillips

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2019 - 2019

IPA - Lawrence Shampine

ResearchPrincipal Investigator · Awarded by Veterans Administration Medical Center · 2006 - 2008

Neurosteroids and Schizophrenia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2001 - 2007

Fellowships, Gifts, and Supported Research


Neurosteroids in PTSD - Biomarkers to Therapeutics · July 2018 - June 2023 Primary Mentor, FDA Sponsor, Study Physician · Awarded by: VA Career Development Award to Steven Szabo, MD The goal of this project is to conduct a randomized controlled trial in OEF/OIF/OND Veterans with PTSD to determine if adjunctive DHEA improves PTSD symptoms. Neurosteroid profiles will be quantified by mass spectrometry at baseline and post-treatment to investigate biomarker candidates of therapeutic response.
Biomarker Candidates in Gulf War Veterans: A 10-year Follow-up Investigation · July 2018 - June 2022 Principal Investigator · Awarded by: VA Merit Award The goal of this project is to investigate biomarker candidates in Gulf War Era Veterans at baseline and 10-year follow-up. This project also includes a neuroimaging component. Blood and neuroimaging biomarker candidates will be investigated as predictors of risk and resilience for Gulf War-related illnesses.
Neurosteroid Intervention in Gulf War Veterans Illnesses (GWVI) · April 2014 - December 2017 Principal Investigator · Awarded by: VA Merit Award The goals of this project are to conduct a randomized controlled trial utilizing an adjunctive neurosteroid in Gulf War Veterans with GWVI, to characterize the pharmocokinetic parameters of the intervention, and to conduct candidate biomarker investigations of potential predictors of therapeutic response utilizing mass spectrometry strategies.
Neuroactive Steroids in OEF/OIF Veterans with TBI · July 2011 - December 2016 Principal Investigator · Awarded by: VA Merit Award The goal of this project is to conduct a randomized controlled trial utilizing a neurosteroid intervention in OEF/OIF Veterans with a history of mild traumatic brain injury (TBI). A subset of participants will also receive neuroimaging to determine fMRI correlates to therapeutic response. Mass spectrometry-based methodologies will be utilized to characterize neurosteroid profiles as candidate biomarkers of therapeutic response.

External Relationships


  • Washington University in St. Louis

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.