Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • D.Phil., University of Tokyo (Japan) 2005
• Research
• 

  Selected Grants

  • Novel Immunogens to Elicit Broadly Cross-reactive Antibodies That Target the Hemagglutinin Head Trimer Interface awarded by National Institutes of Health 2021 - 2025
  • Structure-function analysis of infection- and vaccine-induced B-cell repertoires awarded by Boston Children's Hospital 2014 - 2022
  • Epitope focusing by molecular grafting of subdominant epitopes to achieve a universal-influenza vaccine. awarded by Massachusetts General Hospital 2020 - 2022
  • Immunity to novel T/F SHIVs: variability in the co-evolution of virus and host immunity awarded by National Institutes of Health 2017 - 2022
  • SHIV/HIV Env-Antibody Coevolution as a Guide to Iterative Vaccine Design awarded by University of Pennsylvania 2017 - 2022
  • Modeling affinity maturation at molecular resolution awarded by Boston University 2015 - 2020
  • Attenuated HSV Vaccines That Induce Protective Mucosal Antibodies awarded by Albert Einstein College of Medicine 2016 - 2020
  • Testing the Nearest Neighbor Approach to Active Vaccination for HIV-1 awarded by University of Washington 2014 - 2017
  • Eliciting B cells to produce anti-HIV gp41 MPER-specific neutralizing antibodies, Identifying Critical Stages in Vaccine Indcued HIV-1 Immunity - Project 4 awarded by Dana-Farber Cancer Institute 2010 - 2015
  • B-cell Tolerance and Humoral Immunity to HIV-1 awarded by National Institutes of Health 2009 - 2014
  • Analysis of the Murine Antibody Repertoire awarded by National Institutes of Health 2009 - 2011
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Nojima, Takuya, Alexander E. Reynolds, Daisuke Kitamura, Garnett Kelsoe, and Masayuki Kuraoka. “Tracing Self-Reactive B Cells in Normal Mice.” J Immunol 205, no. 1 (July 1, 2020): 90–101. https://doi.org/10.4049/jimmunol.1901015.
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    • Bajic, Goran, Max J. Maron, Yu Adachi, Taishi Onodera, Kevin R. McCarthy, Charles E. McGee, Gregory D. Sempowski, et al. “Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope.” Cell Host Microbe 25, no. 6 (June 12, 2019): 827-835.e6. https://doi.org/10.1016/j.chom.2019.04.003.
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    • Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.
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    • Kuraoka, Masayuki, Aaron G. Schmidt, Takuya Nojima, Feng Feng, Akiko Watanabe, Daisuke Kitamura, Stephen C. Harrison, Thomas B. Kepler, and Garnett Kelsoe. “Complex Antigens Drive Permissive Clonal Selection in Germinal Centers.” Immunity 44, no. 3 (March 15, 2016): 542–52. https://doi.org/10.1016/j.immuni.2016.02.010.
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    • McWilliams, Laurie, Kuei-Ying Su, Xiaoe Liang, Dongmei Liao, Serina Floyd, Joshua Amos, M Anthony Moody, Garnett Kelsoe, and Masayuki Kuraoka. “The human fetal lymphocyte lineage: identification by CD27 and LIN28B expression in B cell progenitors.” J Leukoc Biol 94, no. 5 (November 2013): 991–1001. https://doi.org/10.1189/jlb.0113048.
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    • Kuraoka, Masayuki, T Matt Holl, Dongmei Liao, Mandy Womble, Derek W. Cain, Alexander E. Reynolds, and Garnett Kelsoe. “Activation-induced cytidine deaminase mediates central tolerance in B cells.” Proc Natl Acad Sci U S A 108, no. 28 (July 12, 2011): 11560–65. https://doi.org/10.1073/pnas.1102571108.
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    • Kuraoka, Masayuki, Dongmei Liao, Kaiyong Yang, Sallie D. Allgood, Marc C. Levesque, Garnett Kelsoe, and Yoshihiro Ueda. “Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.” J Immunol 183, no. 5 (September 1, 2009): 3237–48. https://doi.org/10.4049/jimmunol.0901548.
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    • Holl, T. M., M. Kuraoka, D. Liao, L. Verkoczy, M. A. Moody, M. Alam, H. Liao, B. F. Haynes, and G. H. Kelsoe. “P04-44. Generation of antibody responses to HIV-1 membrane proximal external region (MPER) antigen.” Retrovirology 6, no. SUPPL. 3 (2009): P72.

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