Scholars@Duke
Holman Page McAdams

Holman Page McAdams

Consulting Associate in the Department of Radiology
Radiology, Cardiothoracic Imaging
mcada003@mc.duke.edu
Box 3808 Med Ctr, Durham, NC 27710
2523 Hosp South, Durham, NC 27710

Selected Publications

Radiographic Imaging of Community-Acquired Pneumonia: A Case-Based Review.

Journal Article Infect Dis Clin North Am · March 2024 The chest radiograph is the most common imaging examination performed in most radiology departments, and one of the more common indications for these studies is suspected infection. Radiologists must therefore be aware of less common radiographic patterns ... Full text Link to item Cite

Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease.

Journal Article Respir Med · March 2023 INTRODUCTION: Recent evidence suggests a high prevalence of undiagnosed chronic obstructive pulmonary disease (COPD). These individuals are at risk of exacerbations and delayed treatment. We analyzed an at-risk population for the prevalence of abnormal spi ... Full text Link to item Cite

Imaging of Smoking and Vaping Related Diffuse Lung Injury.

Journal Article Radiol Clin North Am · November 2022 Lung injury associated with smoking tobacco or other substances results in a variety of clinical presentations and imaging patterns, depending on mechanism of injury and substance inhaled. Patients may present in the acute setting, as in the case of acute ... Full text Link to item Cite

Radiographic Imaging of Community-Acquired Pneumonia: A Case-Based Review.

Journal Article Radiol Clin North Am · May 2022 The chest radiograph is the most common imaging examination performed in most radiology departments, and one of the more common indications for these studies is suspected infection. Radiologists must therefore be aware of less common radiographic patterns ... Full text Link to item Cite

Mediastinal Lymphadenopathy in the National Lung Screening Trial (NLST) Is Associated with Interval Lung Cancer.

Journal Article Radiology · March 2022 Background There are currently no evidence-based guidelines for the management of enlarged mediastinal lymph nodes found on lung cancer screening (LCS) CT scans. Purpose To assess the frequency and clinical significance of enlarged mediastinal lymph nodes ... Full text Link to item Cite

Hyperpolarized 129Xe MRI and Spectroscopy of Gas-Exchange Abnormalities in Nonspecific Interstitial Pneumonia.

Journal Article Radiology · October 2021 Background Recent studies demonstrate that antifibrotic drugs previously reserved for idiopathic pulmonary fibrosis (IPF) may slow progression in other interstitial lung diseases (ILDs), creating an urgent need for tools that can sensitively assess disease ... Full text Link to item Cite

Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort.

Journal Article Chest · October 2021 BACKGROUND: Attenuation of transforming growth factor β by blocking angiotensin II has been shown to reduce emphysema in a murine model. General population studies have demonstrated that the use of angiotensin converting enzyme inhibitors (ACEis) and angio ... Full text Link to item Cite

Managing Incidental Findings on Thoracic CT: Lung Findings. A White Paper of the ACR Incidental Findings Committee.

Journal Article J Am Coll Radiol · September 2021 The ACR Incidental Findings Committee presents recommendations for managing incidentally detected lung findings on thoracic CT. The Chest Subcommittee is composed of thoracic radiologists who endorsed and developed the provided guidance. These recommendati ... Full text Link to item Cite

The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers.

Journal Article Chest · September 2021 BACKGROUND: Smokers manifest varied phenotypes of pulmonary impairment. RESEARCH QUESTION: Which pulmonary phenotypes are associated with coronary artery disease (CAD) in smokers? STUDY DESIGN AND METHODS: We analyzed data from the University of Pittsburgh ... Full text Link to item Cite

Complications of Lung Transplantation: Update on Imaging Manifestations and Management.

Journal Article Radiol Cardiothorac Imaging · August 2021 As lung transplantation has become the most effective definitive treatment option for end-stage chronic respiratory diseases, yearly rates of this surgery have been steadily increasing. Despite improvement in surgical techniques and medical management of t ... Full text Link to item Cite

Cardio-Respiratory tolerability of perfluoropropaneEnhanced MRI of pulmonary ventilation

Conference Journal of Lung, Pulmonary & Respiratory Research · December 30, 2020 Rationale: Recent advances in perfluoropropane magnetic resonance imaging of the lung have provided the means to assess pulmonary ventilation and gas distribution throughout the pulmonary airways and acini in a non-invasive manner. Objectives: The ... Full text Cite

The St. George's Respiratory Questionnaire Definition of Chronic Bronchitis May Be a Better Predictor of COPD Exacerbations Compared With the Classic Definition.

Journal Article Chest · October 2019 BACKGROUND: Chronic bronchitis (CB) increases risk of COPD exacerbations. We have shown that the St. George's Respiratory Questionnaire (SGRQ) CB definition identifies patients with a similar clinical phenotype as classically defined CB. Whether the SGRQ C ... Full text Link to item Cite

Multireader Determination of Clinically Significant Obstruction Using Hyperpolarized 129Xe-Ventilation MRI.

Journal Article AJR Am J Roentgenol · April 2019 OBJECTIVE: The objective of our study was to identify the magnitude and distribution of ventilation defect scores (VDSs) derived from hyperpolarized (HP) 129Xe-MRI associated with clinically relevant airway obstruction. MATERIALS AND METHODS: From 2012 to ... Full text Link to item Cite

A protocol for quantifying cardiogenic oscillations in dynamic 129 Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis.

Journal Article NMR Biomed · January 2019 The spectral parameters of hyperpolarized 129 Xe exchanging between airspaces, interstitial barrier, and red blood cells (RBCs) are sensitive to pulmonary pathophysiology. This study sought to evaluate whether the dynamics of 129 Xe spectroscopy provide ad ... Full text Link to item Cite

Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study.

Journal Article Am J Respir Crit Care Med · December 1, 2018 RATIONALE: Increasing awareness of the prevalence and significance of Preserved Ratio Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative for Chronic Obstructive Lung Disease (GOLD)-unclassified spirometry, has expanded the ... Full text Link to item Cite

Managing Incidental Findings on Thoracic CT: Mediastinal and Cardiovascular Findings. A White Paper of the ACR Incidental Findings Committee.

Journal Article J Am Coll Radiol · August 2018 The ACR Incidental Findings Committee presents recommendations for managing incidentally detected mediastinal and cardiovascular findings found on CT. The Chest Subcommittee was composed of thoracic radiologists who developed the provided guidance. These r ... Full text Link to item Cite

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease.

Journal Article J Allergy Clin Immunol · June 2018 BACKGROUND: Eosinophilic airway inflammation in patients with chronic obstructive pulmonary disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting potential shared mechanisms with eosinophilic asthma. However, there is no ... Full text Link to item Cite

Uncovering a third dissolved-phase 129 Xe resonance in the human lung: Quantifying spectroscopic features in healthy subjects and patients with idiopathic pulmonary fibrosis.

Journal Article Magn Reson Med · October 2017 PURPOSE: The purpose of this work was to accurately characterize the spectral properties of hyperpolarized 129 Xe in patients with idiopathic pulmonary fibrosis (IPF) compared to healthy volunteers. METHODS: Subjects underwent hyperpolarized 129 Xe breath- ... Full text Link to item Cite

Novel Magnetic Resonance Imaging for Assessment of Bronchial Stenosis in Lung Transplant Recipients.

Journal Article Am J Transplant · July 2017 Bronchial stenosis in lung transplant recipients is a common disorder that adversely affects clinical outcomes. It is evaluated by spirometry, CT scanning, and bronchoscopy with significant limitations. We hypothesize that MRI using both ultrashort echo ti ... Full text Link to item Cite

Quantitative analysis of hyperpolarized 129 Xe gas transfer MRI.

Journal Article Med Phys · June 2017 PURPOSE: Hyperpolarized 129 Xe magnetic resonance imaging (MRI) using Dixon-based decomposition enables single-breath imaging of 129 Xe in the airspaces, interstitial barrier tissues, and red blood cells (RBCs). However, methods to quantitatively visualize ... Full text Link to item Cite

Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women.

Journal Article Am J Respir Cell Mol Biol · March 2017 Chronic obstructive pulmonary disease (COPD) is a complex disease with strong environmental and genetic influences and sexually dimorphic features. Although genetic risk factors for COPD have been identified, much of the heritability remains unexplained. S ... Full text Link to item Cite

Hyperpolarized 129Xenon Magnetic Resonance Imaging to Quantify Regional Ventilation Differences in Mild to Moderate Asthma: A Prospective Comparison Between Semiautomated Ventilation Defect Percentage Calculation and Pulmonary Function Tests.

Journal Article Invest Radiol · February 2017 OBJECTIVES: The aim of this study was to investigate ventilation in mild to moderate asthmatic patients and age-matched controls using hyperpolarized (HP) Xenon magnetic resonance imaging (MRI) and correlate findings with pulmonary function tests (PFTs). M ... Full text Link to item Cite

Multi-Institutional Evaluation of Digital Tomosynthesis, Dual-Energy Radiography, and Conventional Chest Radiography for the Detection and Management of Pulmonary Nodules.

Journal Article Radiology · January 2017 Purpose To conduct a multi-institutional, multireader study to compare the performance of digital tomosynthesis, dual-energy (DE) imaging, and conventional chest radiography for pulmonary nodule detection and management. Materials and Methods In this binat ... Full text Link to item Cite

Persistent pulmonary subsolid nodules with solid portions of 5 mm or smaller: Their natural course and predictors of interval growth.

Journal Article Eur Radiol · June 2016 OBJECTIVE: To investigate the natural course of persistent pulmonary subsolid nodules (SSNs) with solid portions ≤5 mm and the clinico-radiological features that influence interval growth over follow-ups. METHODS: From 2005 to 2013, the natural courses of ... Full text Link to item Cite

Single-breath clinical imaging of hyperpolarized (129)Xe in the airspaces, barrier, and red blood cells using an interleaved 3D radial 1-point Dixon acquisition.

Journal Article Magn Reson Med · April 2016 PURPOSE: We sought to develop and test a clinically feasible 1-point Dixon, three-dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of (129)Xe in the airspaces, barrier, and red blood cells (RBCs) in a single breath. The approac ... Full text Link to item Cite

Abnormalities in hyperpolarized (129)Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease.

Journal Article Pulm Circ · March 2016 The diagnosis of pulmonary vascular disease (PVD) is usually based on hemodynamic and/or clinical criteria. Noninvasive imaging of the heart and proximal vasculature can also provide useful information. An alternate approach to such criteria in the diagnos ... Full text Link to item Cite

Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort.

Journal Article BMC Pulm Med · February 10, 2016 BACKGROUND: Despite inhaled medications that decrease exacerbation risk, some COPD patients experience frequent exacerbations. We determined prospective risk factors for exacerbations among subjects in the COPDGene Study taking inhaled medications. METHODS ... Full text Link to item Cite

Percutaneous transthoracic localization of pulmonary nodules under C-arm cone-beam CT virtual navigation guidance.

Journal Article Diagn Interv Radiol · 2016 PURPOSE: We aimed to describe our initial experience with percutaneous transthoracic localization (PTL) of pulmonary nodules using a C-arm cone-beam CT (CBCT) virtual navigation guidance system. METHODS: From February 2013 to March 2014, 79 consecutive pat ... Full text Link to item Cite

Differentiating Early Stage And Later Stage Ipf Using Hyperpolarized 129xe Ventilation Mri

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2016 Link to item Cite

Persistent Pure Ground-Glass Nodules Larger Than 5 mm: Differentiation of Invasive Pulmonary Adenocarcinomas From Preinvasive Lesions or Minimally Invasive Adenocarcinomas Using Texture Analysis.

Journal Article Invest Radiol · November 2015 OBJECTIVE: To evaluate the differentiating potentials of computed tomography texture analysis for invasive pulmonary adenocarcinomas (IPAs) from their preinvasive lesions or minimally invasive adenocarcinomas (MIAs) manifesting as persistent pure ground-gl ... Full text Link to item Cite

Prognostic value of computed tomography texture features in non-small cell lung cancers treated with definitive concomitant chemoradiotherapy.

Journal Article Invest Radiol · October 2015 OBJECTIVES: The aim of this study was to investigate whether the computed tomography (CT) texture features of primary tumors are associated with the overall survival (OS) of non-small cell lung cancer (NSCLC) patients undergoing definitive concomitant chem ... Full text Link to item Cite

Dose and pulse sequence considerations for hyperpolarized (129)Xe ventilation MRI.

Journal Article Magn Reson Imaging · September 2015 PURPOSE: The aim of this study was to evaluate the effect of hyperpolarized (129)Xe dose on image signal-to-noise ratio (SNR) and ventilation defect conspicuity on both multi-slice gradient echo and isotropic 3D-radially acquired ventilation MRI. MATERIALS ... Full text Link to item Cite

Hyperpolarized Gas MR Imaging: Technique and Applications.

Journal Article Magn Reson Imaging Clin N Am · May 2015 Functional imaging offers information more sensitive to changes in lung structure and function. Hyperpolarized helium ((3)He) and xenon ((129)Xe) MR imaging of the lungs provides sensitive contrast mechanisms to probe changes in pulmonary ventilation, micr ... Full text Link to item Cite

Extending semiautomatic ventilation defect analysis for hyperpolarized (129)Xe ventilation MRI.

Journal Article Acad Radiol · December 2014 RATIONALE AND OBJECTIVES: Clinical deployment of hyperpolarized (129)Xe magnetic resonance imaging requires accurate quantification and visualization of the ventilation defect percentage (VDP). Here, we improve the robustness of our previous semiautomated ... Full text Link to item Cite

Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.

Journal Article Am J Respir Cell Mol Biol · November 2014 Hypoxemia is a major complication of chronic obstructive pulmonary disease (COPD) that correlates with disease prognosis. Identifying genetic variants associated with oxygenation may provide clues for deciphering the heterogeneity in prognosis among patien ... Full text Link to item Cite

Automated characterization of perceptual quality of clinical chest radiographs: validation and calibration to observer preference.

Journal Article Med Phys · November 2014 PURPOSE: The authors previously proposed an image-based technique [Y. Lin et al. Med. Phys. 39, 7019-7031 (2012)] to assess the perceptual quality of clinical chest radiographs. In this study, an observer study was designed and conducted to validate the ou ... Full text Link to item Cite

Measuring diffusion limitation with a perfusion-limited gas--hyperpolarized 129Xe gas-transfer spectroscopy in patients with idiopathic pulmonary fibrosis.

Journal Article J Appl Physiol (1985) · September 15, 2014 Although xenon is classically taught to be a "perfusion-limited" gas, (129)Xe in its hyperpolarized (HP) form, when detected by magnetic resonance (MR), can probe diffusion limitation. Inhaled HP (129)Xe diffuses across the pulmonary blood-gas barrier, and ... Full text Link to item Cite

Validation of an image-based technique to assess the perceptual quality of clinical chest radiographs with an observer study

Journal Article Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2014 We previously proposed a novel image-based quality assessment technique1 to assess the perceptual quality of clinical chest radiographs. In this paper, an observer study was designed and conducted to systematically validate this technique. Ten metrics were ... Full text Cite

Hyperpolarized 129xe Mri To Quantify Regional Ventilation Differences In Older Versus Younger Asthmatics

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2014 Link to item Cite

Hyperpolarized 129xe Spectroscopy As A Biomarker For Gas-Transfer Impairment In Idiopathic Pulmonary Fibrosis

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2014 Link to item Cite

Perfluoropropane gas as a magnetic resonance lung imaging contrast agent in humans.

Journal Article Chest · October 2013 BACKGROUND: Fluorine-enhanced MRI is a relatively inexpensive and straightforward technique that facilitates regional assessments of pulmonary ventilation. In this report, we assess its suitability through the use of perfluoropropane (PFP) in a cohort of h ... Full text Link to item Cite

Probing the regional distribution of pulmonary gas exchange through single-breath gas- and dissolved-phase 129Xe MR imaging.

Journal Article J Appl Physiol (1985) · September 2013 Although some central aspects of pulmonary function (ventilation and perfusion) are known to be heterogeneous, the distribution of diffusive gas exchange remains poorly characterized. A solution is offered by hyperpolarized 129Xe magnetic resonance (MR) im ... Full text Link to item Cite

Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease.

Journal Article NMR Biomed · April 2013 In this study, hyperpolarized (129) Xe MR ventilation and (1) H anatomical images were obtained from three subject groups: young healthy volunteers (HVs), subjects with chronic obstructive pulmonary disease (COPD) and age-matched controls (AMCs). Ventilati ... Full text Link to item Cite

Preliminary evaluation of biplane correlation (BCI) stereographic imaging for lung nodule detection.

Journal Article J Digit Imaging · February 2013 A biplane correlation (BCI) imaging system obtains images that can be viewed in stereo, thereby minimizing overlapping structures. This study investigated whether using stereoscopic visualization provides superior lung nodule detection compared to standard ... Full text Link to item Cite

The effect of averaging adjacent planes for artifact reduction in matrix inversion tomosynthesis.

Journal Article Med Phys · February 2013 PURPOSE: Matrix inversion tomosynthesis (MITS) uses linear systems theory and knowledge of the imaging geometry to remove tomographic blur that is present in conventional backprojection tomosynthesis reconstructions, leaving in-plane detail rendered clearl ... Full text Link to item Cite

Reproducibility Of Hyperpolarized 129xe Mri: Alveolar Capillary Gas-Transfer Spectroscopy And Imaging

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2013 Link to item Cite

An image-based technique to assess the perceptual quality of clinical chest radiographs.

Journal Article Med Phys · November 2012 PURPOSE: Current clinical image quality assessment techniques mainly analyze image quality for the imaging system in terms of factors such as the capture system modulation transfer function, noise power spectrum, detective quantum efficiency, and the expos ... Full text Link to item Cite

The effects of ambient lighting in chest radiology reading rooms.

Journal Article J Digit Imaging · August 2012 Under typical dark chest radiography reading room conditions, a radiologist's pupils contract and dilate as their visual focus intermittently shifts between the high luminance monitor and the darker background wall, resulting in increased visual fatigue an ... Full text Link to item Cite

A computerized scheme for lung nodule detection in multiprojection chest radiography.

Journal Article Med Phys · April 2012 PURPOSE: Our previous study indicated that multiprojection chest radiography could significantly improve radiologists' performance for lung nodule detection in clinical practice. In this study, the authors further verify that multiprojection chest radiogra ... Full text Link to item Cite

Biplane correlation imaging: a feasibility study based on phantom and human data.

Journal Article J Digit Imaging · February 2012 The objective of this study was to implement and evaluate the performance of a biplane correlation imaging (BCI) technique aimed to reduce the effect of anatomic noise and improve the detection of lung nodules in chest radiographs. Seventy-one low-dose pos ... Full text Link to item Cite

Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients.

Journal Article Radiology · January 2012 PURPOSE: To evaluate the safety and tolerability of inhaling multiple 1-L volumes of undiluted hyperpolarized xenon 129 ((129)Xe) followed by up to a 16-second breath hold and magnetic resonance (MR) imaging. MATERIALS AND METHODS: This study was approved ... Full text Link to item Cite

Gray-scale inversion radiographic display for the detection of pulmonary nodules on chest radiographs.

Journal Article Clin Imaging · 2012 The purpose of this study was to investigate gray-scale inversion in nodule detection on chest radiography. Simulated nodules were superimposed randomly onto normal chest radiographs. Six radiologists interpreted 144 chest radiographs during three reading ... Full text Link to item Cite

A patient image-based technique to assess the image quality of clinical chest radiographs

Journal Article Progress in Biomedical Optics and Imaging - Proceedings of SPIE · May 13, 2011 Current clinical image quality assessment techniques mainly analyze image quality for the imaging system in terms of factors such as the capture system DQE and MTF, the exposure technique, and the particular image processing method and processing parameter ... Full text Cite

Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease.

Journal Article Magn Reson Med · April 2011 Given its greater availability and lower cost, (129) Xe apparent diffusion coefficient (ADC) MRI offers an alternative to (3) He ADC MRI. To demonstrate the feasibility of hyperpolarized (129) Xe ADC MRI, we present results from healthy volunteers (HV), ch ... Full text Link to item Cite

Nonsurgical extracardiac vascular shunts in the thorax: clinical and imaging characteristics.

Journal Article Radiographics · September 2010 Extracardiac nonsurgical vascular shunts in the thorax are a group of well-recognized heterogeneous conditions, frequently symptomatic, in which there is diversion of blood flow from one vessel to another or from a vessel to a cardiac chamber. The authors ... Full text Link to item Cite

Hyperpolarized Xe MR imaging of alveolar gas uptake in humans.

Journal Article PLoS One · August 16, 2010 BACKGROUND: One of the central physiological functions of the lungs is to transfer inhaled gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar gas uptake provide only global information and thus lack the sensitivity a ... Full text Open Access Link to item Cite

Hyperpolarized Xe-129 MR Imaging of Alveolar-Capillary Gas Transfer in Healthy Subjects and COPD Patients

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2010 Link to item Cite

Diffusion Weighted Imaging of Hyperpolarized Xe-129 in Patients with Chronic Obstructive Pulmonary Disease

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2010 Link to item Cite

Chest tomosynthesis: technical principles and clinical update.

Journal Article Eur J Radiol · November 2009 Featured Publication Digital tomosynthesis is a radiographic technique that can produce an arbitrary number of section images of a patient from a single pass of the X-ray tube. It utilizes a conventional X-ray tube, a flat-panel detector, a computer-controlled tube mover, and ... Full text Link to item Cite

CT metrics of airway disease and emphysema in severe COPD.

Other Chest · August 2009 BACKGROUND: CT scan measures of emphysema and airway disease have been correlated with lung function in cohorts of subjects with a range of COPD severity. The contribution of CT scan-assessed airway disease to objective measures of lung function and respir ... Full text Link to item Cite

Stochastic noise characteristics in matrix inversion tomosynthesis (MITS).

Journal Article Med Phys · May 2009 Matrix inversion tomosynthesis (MITS) uses known imaging geometry and linear systems theory to deterministically separate in-plane detail from residual tomographic blur in a set of conventional tomosynthesis ("shift-and-add") planes. A previous investigati ... Full text Link to item Cite

Design and Development of a New Multi-Projection X-Ray System for Chest Imaging.

Journal Article IEEE Trans Nucl Sci · February 2009 Overlapping anatomical structures may confound the detection of abnormal pathology, including lung nodules, in conventional single-projection chest radiography. To minimize this fundamental limiting factor, a dedicated digital multi-projection system for c ... Full text Link to item Cite

Imaging appearances of the sternum and sternoclavicular joints.

Journal Article Radiographics · 2009 The sternum and sternoclavicular joints--critical structures of the anterior chest wall--may be affected by various anatomic anomalies and pathologic processes, some of which require treatment. Pectus excavatum and pectus carinatum are common congenital an ... Full text Link to item Cite

Digital tomosynthesis of the chest for lung nodule detection: interim sensitivity results from an ongoing NIH-sponsored trial.

Journal Article Med Phys · June 2008 Featured Publication The authors report interim clinical results from an ongoing NIH-sponsored trial to evaluate digital chest tomosynthesis for improving detectability of small lung nodules. Twenty-one patients undergoing computed tomography (CT) to follow up lung nodules wer ... Full text Link to item Cite

Digital tomosynthesis of the chest.

Journal Article J Thorac Imaging · May 2008 Digital tomosynthesis is a technique that generates an arbitrary number of section images of a patient from a single pass of the x-ray tube. It is under investigation for application to a number of clinical detection tasks, and has recently been implemente ... Full text Link to item Cite

Kaposi sarcoma after bilateral lung transplantation.

Journal Article J Thorac Imaging · February 2008 We describe radiologic findings in 2 patients and 18-fluoro-deoxy-glucose positron emission tomography/computed tomography findings in 1 patient who developed Kaposi sarcoma of the lung after bilateral lung transplantation. These findings included lung nod ... Full text Link to item Cite

Mucoid impactions: finger-in-glove sign and other CT and radiographic features.

Journal Article Radiographics · 2008 Featured Publication Mucoid impaction is a relatively common finding at chest radiography and computed tomography (CT). Both congenital and acquired abnormalities may cause mucoid impaction of the large airways that often manifests as tubular opacities known as the finger-in-g ... Full text Link to item Cite

Gold medal award of the Society of Thoracic Radiology

Journal Article Journal of Thoracic Imaging · August 1, 2007 Full text Cite

The many faces of pulmonary nontuberculous mycobacterial infection.

Journal Article AJR Am J Roentgenol · July 2007 Featured Publication OBJECTIVE: The purpose of this article is to review clinical and radiologic manifestations of pulmonary nontuberculous mycobacterial infection. CONCLUSION: Common and well-recognized patterns of infection include cavitary and bronchiectatic disease and inf ... Full text Link to item Cite

Follicular dendritic cell sarcoma of the mediastinum.

Journal Article AJR Am J Roentgenol · June 2007 Full text Link to item Cite

Multiprojection correlation imaging for improved detection of pulmonary nodules.

Journal Article AJR Am J Roentgenol · May 2007 Featured Publication OBJECTIVE: The purpose of this study was the development and preliminary evaluation of multiprojection correlation imaging with 3D computer-aided detection (CAD) on chest radiographs for cost- and dose-effective improvement of early detection of pulmonary ... Full text Link to item Cite

Recent advances in chest radiography.

Journal Article Radiology · December 2006 Featured Publication There have been many remarkable advances in conventional thoracic imaging over the past decade. Perhaps the most remarkable is the rapid conversion from film-based to digital radiographic systems. Computed radiography is now the preferred imaging modality ... Full text Link to item Cite

Imaging of lung transplantation

Journal Article Applied Radiology · July 1, 2006 Although lung transplants are performed only at regional medical centers, an increasing number of posttransplant patients are found throughout the country. Therefore, it is important that radiologists appropriately image these patients and recognize compli ... Cite

Optimization of the matrix inversion tomosynthesis (MITS) impulse response and modulation transfer function characteristics for chest imaging.

Journal Article Med Phys · March 2006 Matrix inversion tomosynthesis (MITS) uses linear systems theory, along with a priori knowledge of the imaging geometry, to deterministically distinguish between true structure and overlying tomographic blur in a set of conventional tomosynthesis planes. I ... Full text Link to item Cite

The role of genetics and cigarette smoking in the development of pulmonary fibrosis

Conference Respirology · January 2006 Abstract:  Several lines of evidence suggest that genetic factors and environmental exposure play a role in the development of pulmonary fibrosis. The authors evaluated families with familial pulmonary fibrosis (FPF), defined ... Full text Cite

Clinical and pathologic features of familial interstitial pneumonia.

Journal Article Am J Respir Crit Care Med · November 1, 2005 RATIONALE: Several lines of evidence suggest that genetic factors and environmental exposures play a role in the development of pulmonary fibrosis. OBJECTIVES: We evaluated families with 2 or more cases of idiopathic interstitial pneumonia among first-degr ... Full text Link to item Cite

A 73-year-old woman with a cough.

Journal Article Chest · August 2005 Full text Link to item Cite

Comparative scatter and dose performance of slot-scan and full-field digital chest radiography systems.

Journal Article Radiology · June 2005 Featured Publication PURPOSE: To evaluate the scatter, dose, and effective detective quantum efficiency (DQE) performance of a slot-scan digital chest radiography system compared with that of a full-field digital radiography system. MATERIALS AND METHODS: Scatter fraction of a ... Full text Link to item Cite

Pulmonary vein diameter, cross-sectional area, and shape: CT analysis.

Journal Article Radiology · April 2005 PURPOSE: To retrospectively establish normal values for pulmonary vein diameter, cross-sectional area, and shape depicted at computed tomography (CT). MATERIALS AND METHODS: Institutional review board waived patient consent requirement and approved the stu ... Full text Link to item Cite

MO‐D‐I‐6B‐04: Matrix Inversion Tomosynthesis (MITS) Imaging of the Chest

Journal Article Medical Physics · January 1, 2005 Tomosynthesis is a method for reconstructing 3‐dimensional (3‐D) image data from a series of x‐ray projection radiographs, acquired with limited motion of the x‐ray source (typically no more than 40 degrees). Digital tomosynthesis (DTS) is implemented with ... Full text Cite

Positron emission tomography with fluoro-2-deoxy-D-glucose (FDG-PET) in the staging of post transplant lymphoproliferative disorder in lung transplant recipients.

Journal Article J Thorac Imaging · April 2004 Posttransplantation lymphoproliferative disorder (PTLD) is a histologic heterogeneous disease that complicates 4 to 8% of lung transplant recipients. Disease extent is an important prognostic factor and may affect therapy. Positron emission tomography with ... Full text Link to item Cite

Variations in pulmonary venous drainage to the left atrium: implications for radiofrequency ablation.

Journal Article Radiology · March 2004 PURPOSE: To evaluate and classify the various drainage patterns of the pulmonary veins as depicted with thin-section chest computed tomography (CT). MATERIALS AND METHODS: Thin-section (2.5-mm collimation) contrast material-enhanced CT scans of 201 consecu ... Full text Link to item Cite

Posttransplant lymphoproliferative disorder: incidence, presentation, and response to treatment in lung transplant recipients.

Journal Article Chest · October 2003 INTRODUCTION: Posttransplant lymphoproliferative disorder (PTLD) is a relatively infrequent but devastating complication that occurs after solid-organ transplantation. Although the optimal treatment for this condition is unknown, rituximab, a murine/human ... Full text Link to item Cite

Pulmonary vasculitis: CT features.

Journal Article Semin Respir Crit Care Med · August 2003 The pulmonary vasculitides are a heterogeneous group of inflammatory disorders that may be primarily localized to the pulmonary vasculature or be systemic in nature. The primary pulmonary vasculitides usually affect small vessels, whereas the systemic vasc ... Full text Link to item Cite

Pleural effusions in lung transplant recipients: image-guided small-bore catheter drainage.

Journal Article Radiology · July 2003 PURPOSE: To assess the efficacy of treating pleural effusions in lung transplant recipients with small-bore catheter drainage. MATERIALS AND METHODS: Chest radiographs and computed tomographic (CT) scans obtained in 31 lung transplant recipients who had pl ... Full text Link to item Cite

Multiplanar and three-dimensional imaging of the thorax.

Journal Article Radiol Clin North Am · May 2003 Featured Publication Although axial images are sufficient for diagnosis in most instances, knowledge of multiplanar imaging techniques is essential to apply them in appropriate circumstances. In particular, appropriately applied multiplanar imaging adds confidence to interpret ... Full text Link to item Cite

Bronchiolitis obliterans syndrome in lung transplant recipients: correlation of computed tomography findings with bronchiolitis obliterans syndrome stage.

Journal Article J Thorac Imaging · April 2003 The purpose of this study was to correlate the extent of computed tomographic (CT) findings with the severity of respiratory dysfunction in lung transplant recipients with bronchiolitis obliterans syndrome (BOS). Eighty-nine conventional and 61 thin-sectio ... Full text Link to item Cite

"Crazy-paving" pattern at thin-section CT of the lungs: radiologic-pathologic overview.

Journal Article Radiographics · 2003 The "crazy-paving" pattern is a common finding at thin-section computed tomography (CT) of the lungs. It consists of scattered or diffuse ground-glass attenuation with superimposed interlobular septal thickening and intralobular lines. This finding has a v ... Full text Link to item Cite

Computed tomography of partial anomalous pulmonary venous connection in adults.

Journal Article J Comput Assist Tomogr · 2003 OBJECTIVES: To systematically describe the imaging features and clinical correlates of a partial anomalous pulmonary venous connection diagnosed on computed tomography (CT) in adults. METHODS: Twenty-nine adults with a partial anomalous pulmonary venous co ... Full text Link to item Cite

From the archives of the AFIP: Localized fibrous tumor of the pleura.

Journal Article Radiographics · 2003 Eighty-two localized fibrous tumors of the pleura (LFTP) were reviewed retrospectively for the clinical, pathologic, and radiologic findings. Forty-four women and 38 men ranged in age from 17 to 78 years (mean, 54.7 years). Sixty-four benign LFTP ranged in ... Full text Link to item Cite

Bronchogenic carcinoma after lung transplantation: frequency, clinical characteristics, and imaging findings.

Journal Article Radiology · July 2002 PURPOSE: To determine the frequency, clinical characteristics, and radiologic findings of bronchogenic carcinoma in patients surviving more than 1 month after lung transplantation. MATERIALS AND METHODS: The study population was composed of 2,168 consecuti ... Full text Link to item Cite

Usefulness of imaging-guided catheter drainage and talc sclerotherapy in patients with metastatic gynecologic malignancies and symptomatic pleural effusions.

Journal Article AJR Am J Roentgenol · July 2002 OBJECTIVE: The purpose of our study was to assess the usefulness of imaging-guided catheter drainage and talc sclerotherapy in patients with metastatic gynecologic malignancies and symptomatic pleural effusions and to assess the affect of ascites on the su ... Full text Link to item Cite

Progression of idiopathic pulmonary fibrosis in native lungs after single lung transplantation.

Journal Article Chest · June 2002 This retrospective, single-center study was conducted to assess the response of native idiopathic pulmonary fibrosis (IPF) lungs to a potent cyclosporine-based immunosuppressive regimen in single-lung transplantation recipients. The study included IPF pati ... Full text Link to item Cite

Computed tomography diagnosis of macroscopic pulmonary fat embolism.

Journal Article J Thorac Imaging · April 2002 Pulmonary fat embolism probably occurs commonly after major orthopedic injuries and after orthopedic surgery. Furthermore, tiny fat emboli can often be shown by transesophageal echocardiography during orthopedic surgery. However, large macroscopic are rare ... Full text Link to item Cite

Drug-induced lung injury.

Journal Article Semin Roentgenol · January 2002 Featured Publication Lung injury is an increasing cause of morbidity and mortality in patients treated with cytotoxic and noncytotoxic drugs. Prompt diagnosis is important because early drug-induced lung injury will often regress with the cessation of therapy. Diagnosis requir ... Full text Link to item Cite

Low-dose spiral CT: application to surface-rendered three-dimensional imaging of central airways.

Journal Article J Comput Assist Tomogr · 2002 PURPOSE: The purpose of this work was to assess the utility of low-dose spiral CT for three-dimensional imaging of the central airways. METHOD: Spiral CT was performed in 15 patients using two tube currents (50 and 240 mA), producing 30 CT data sets. Surfa ... Full text Link to item Cite

Relapsing polychondritis affecting the lower respiratory tract.

Journal Article AJR Am J Roentgenol · January 2002 OBJECTIVE: The purpose of this study was to describe the CT findings of lower respiratory tract involvement by relapsing polychondritis. CONCLUSION: The most common CT manifestations were increased attenuation and smooth thickening of airway walls. Trachea ... Full text Link to item Cite

High-resolution CT of drug-induced lung disease.

Journal Article Radiol Clin North Am · January 2002 Featured Publication Drug-induced pulmonary toxicity is increasing and early diagnosis is important because of the associated morbidity and mortality. Diagnosis is often difficult and is usually based on a history of drug therapy and exclusion of infection, radiation pneumonit ... Full text Link to item Cite

Reperfusion edema after lung transplantation: effect of daclizumab.

Journal Article Radiology · November 2001 PURPOSE: To determine if daclizumab, an interleukin-2 antagonist, reduced the severity of reperfusion edema in lung transplant recipients. MATERIALS AND METHODS: Eighty-five patients who were to undergo 86 consecutive lung transplants were included; 43 (50 ... Full text Link to item Cite

Idiopathic multilocular thymic cyst: CT features with clinical and histopathologic correlation.

Journal Article AJR Am J Roentgenol · October 2001 OBJECTIVE: We performed this study to describe the CT features of idiopathic multilocular thymic cysts with clinical and histopathologic correlation. CONCLUSION: Multilocular thymic cysts typically manifest on CT as unilocular or multilocular cystic thymic ... Full text Link to item Cite

Multidimensional imaging of the thorax: practical applications.

Journal Article J Thorac Imaging · October 2001 Over the past decade, faster CT scan times, thinner collimation, and the development of multirow detectors, coupled with the increasing capability of computers to process large amounts of data in short periods of time, have lead to an expansion in the abil ... Full text Link to item Cite

Congenital unilateral pulmonary vein atresia: radiologic findings in three adult patients.

Journal Article AJR Am J Roentgenol · September 2001 OBJECTIVE: The purpose of our study is to describe the radiologic findings of adult patients presenting with congenital unilateral pulmonary vein atresia. CONCLUSION: Chest radiography in affected patients typically reveals a small hemithorax and ipsilater ... Full text Link to item Cite

CT fluoroscopy--guided interventional procedures: techniques and radiation dose to radiologists.

Journal Article Radiology · July 2001 PURPOSE: To determine the radiation dose to radiologists who perform computed tomographic (CT) fluoroscopic interventional procedures by using a quick-check method and a low-milliampere technique. MATERIALS AND METHODS: Two hundred twenty CT fluoroscopy--g ... Full text Link to item Cite

Sarcoidosis induced by interferon therapy.

Journal Article AJR Am J Roentgenol · July 2001 Full text Link to item Cite

Frequency and CT findings of recurrent disease after lung transplantation.

Journal Article Radiology · May 2001 PURPOSE: To determine the frequency and computed tomographic (CT) findings of recurrence of the primary disease after lung transplantation at six North American lung transplantation centers. MATERIALS AND METHODS: Medical records of 1,394 lung transplant r ... Full text Link to item Cite

Influenza pneumonia in lung transplant recipients: clinical features and association with bronchiolitis obliterans syndrome.

Journal Article Chest · April 2001 Influenza infection is increasingly recognized to cause significant morbidity and mortality in the community, especially in pediatric patients and elderly persons. Influenza infection, however, has not been well described among thoracic organ transplant re ... Full text Link to item Cite

Diffuse abnormalities of the trachea and main bronchi.

Journal Article AJR Am J Roentgenol · March 2001 Full text Link to item Cite

Focal abnormalities of the trachea and main bronchi.

Journal Article AJR Am J Roentgenol · March 2001 Full text Link to item Cite

Fibrosing mediastinitis.

Journal Article Radiographics · 2001 Fibrosing mediastinitis is a rare benign disorder caused by proliferation of acellular collagen and fibrous tissue within the mediastinum. Although many cases are idiopathic, many (and perhaps most) cases in the United States are thought to be caused by an ... Full text Link to item Cite

Integration of peripheral blood biomarkers with computed tomography to differentiate benign from malignant pulmonary opacities.

Journal Article Cancer Detect Prev · 2001 Our purpose was to determine whether peripheral blood biomarkers MUC1 and CK19 could be used to complement imaging studies in differentiating benign from malignant indeterminate pulmonary nodules or masses detected on computed tomography CT. One hundred an ... Link to item Cite

Complications (excluding hyperinflation) involving the native lung after single-lung transplantation: incidence, radiologic features, and clinical importance.

Journal Article Radiology · January 2001 PURPOSE: To determine the incidence, importance, and radiologic features of native lung complications after single-lung transplantation. MATERIALS AND METHODS: Seventeen (15%) of 111 single-lung transplant recipients developed native lung complications (ex ... Full text Link to item Cite

Computed tomography pulmonary angiography: Diagnostic pitfalls and artifacts

Journal Article Applied Radiology · January 1, 2001 Cite

Bronchial atresia: Clinical observations and review of the literature

Journal Article Clinical Pulmonary Medicine · January 1, 2001 Bronchial atresia is a rare condition that is caused by the congenital occlusion of a proximal bronchus, which is likely the consequence of a vascular insult that occurs early in gestation. Because the involved bronchus does not communicate with the centra ... Full text Cite

Epithelioid hemangioendothelioma of the pleura: clinical and radiologic features.

Journal Article AJR Am J Roentgenol · December 2000 OBJECTIVE: The purpose of our study was to describe the clinical and radiologic features of epithelioid hemangioendothelioma of the pleura. CONCLUSION: Pleural epithelioid hemangioendothelioma is an uncommon malignancy that typically affects older men, who ... Full text Link to item Cite

Bronchogenic cyst: imaging features with clinical and histopathologic correlation.

Journal Article Radiology · November 2000 PURPOSE: To characterize the imaging features of bronchogenic cysts. MATERIALS AND METHODS: The computed tomographic (CT) and/or magnetic resonance (MR) or ultrasonographic images in 68 histopathologically proved cases of bronchogenic cyst in 38 male and 3 ... Full text Link to item Cite

The "High-Riding" superior pericardial recess: CT findings.

Journal Article AJR Am J Roentgenol · October 2000 OBJECTIVE. We recently observed patients in whom the superior pericardial recess extended cephalad ("high-riding") into the right paratracheal region. In these patients, differentiation from mediastinal lymphadenopathy or mass was difficult. The purpose of ... Full text Link to item Cite

FDG PET of pleural effusions in patients with non-small cell lung cancer.

Journal Article AJR Am J Roentgenol · July 2000 OBJECTIVE: We determined the ability of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) to differentiate benign and malignant pleural effusions in patients with non-small cell lung cancer. MATERIALS AND METHODS: Over a 6-year period, we rev ... Full text Link to item Cite

Non-small cell lung cancer: FDG PET for nodal staging in patients with stage I disease.

Journal Article Radiology · June 2000 PURPOSE: To determine the accuracy of 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in the evaluation of regional lymph nodes in patients with stage I non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Imaging and ... Full text Link to item Cite

Hypersensitivity pneumonitis.

Journal Article AJR Am J Roentgenol · April 2000 Full text Link to item Cite

Percutaneous management of intrapulmonary air and fluid collections.

Journal Article Radiol Clin North Am · March 2000 The radiologist's role in the management of intrapulmonary air and fluid collections is becoming more important. Improvements in percutaneous interventional techniques now allow the radiologist to offer patients an alternative treatment option with less mo ... Full text Link to item Cite

Novel techniques for MR imaging of pulmonary airspaces.

Journal Article Magn Reson Imaging Clin N Am · February 2000 Featured Publication Hyperpolarized gas- and molecular oxygen-enhanced MR imaging are two new techniques for high-resolution MR imaging of pulmonary airspaces. Both techniques produce excellent images in a safe, reproducible, and technically feasible manner. Because morphologi ... Link to item Cite

MR imaging of mediastinal masses.

Journal Article Magn Reson Imaging Clin N Am · February 2000 Although ongoing developments in MR imaging have resulted in improved image quality and decreased acquisition time, MR imaging is largely used as an adjunct to CT scanning in the evaluation of mediastinal abnormalities. In this role, MR imaging often provi ... Link to item Cite

Solitary pulmonary nodules: Part II. Evaluation of the indeterminate nodule.

Journal Article Radiographics · 2000 Various strategies may be used to evaluate indeterminate solitary pulmonary nodules. Growth rate assessment is an important and cost-effective step in the evaluation of these nodules. Clinical features (eg, patient age, history of prior malignancy, present ... Full text Link to item Cite

Pulmonary drug toxicity: radiologic and pathologic manifestations.

Journal Article Radiographics · 2000 Pulmonary drug toxicity is increasingly being diagnosed as a cause of acute and chronic lung disease. Numerous agents including cytotoxic and noncytotoxic drugs have the potential to cause pulmonary toxicity. The clinical and radiologic manifestations of t ... Full text Link to item Cite

Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions.

Journal Article Radiographics · 2000 The solitary pulmonary nodule is a common radiologic abnormality that is often detected incidentally. Although most solitary pulmonary nodules have benign causes, many represent stage I lung cancers and must be distinguished from benign nodules in an exped ... Full text Link to item Cite

Thoracic manifestations of neurofibromatosis-I.

Journal Article AJR Am J Roentgenol · December 1999 The intrathoracic manifestations of neurofibromatosis-I are protean and can, on occasion, mimic those of malignancy. Many of the intrathoracic findings are characteristic of the disease and can be expected to be present. Knowledge of the full spectrum of r ... Full text Link to item Cite

Respiratory viral infections in lung transplant recipients: radiologic findings with clinical correlation.

Journal Article Radiology · December 1999 PURPOSE: To evaluate radiologic finding of respiratory viral infection in lung transplant recipients with clinical correlation. MATERIALS AND METHODS: Over 5 years, 21 episodes of respiratory viral infection (parainfluenza [n = 9], respiratory syncytial vi ... Full text Link to item Cite

Sclerotherapy for malignant pleural effusions

Journal Article Pneumologie · December 1, 1999 Cite

Thymic hyperplasia after high-dose chemotherapy and autologous stem cell transplantation: incidence and significance in patients with breast cancer.

Journal Article AJR Am J Roentgenol · November 1999 OBJECTIVE: The purpose of this study was to determine the incidence and clinical significance of thymic hyperplasia after high-dose chemotherapy and autologous stem cell transplantation for treatment of metastatic or high-risk primary (with at least four p ... Full text Link to item Cite

Non-small cell lung cancer: FDG-PET imaging.

Journal Article J Thorac Imaging · October 1999 Positron emission tomography is a clinically useful imaging modality that complements conventional radiologic studies in the evaluation of focal pulmonary opacities, lung cancer staging, tumor recurrence, treatment response, and prognosis. ... Full text Link to item Cite

Cystic fibrosis: usefulness of thoracic CT in the examination of patients before lung transplantation.

Journal Article Radiology · October 1999 PURPOSE: To evaluate the usefulness of thoracic computed tomography (CT) in the pre-lung transplantation examination of patients with cystic fibrosis (CF). MATERIALS AND METHODS: Fifty-six patients (age range, 12-42 years) with CF were evaluated for possib ... Full text Link to item Cite

Hyperpolarized 3He-enhanced MR imaging of lung transplant recipients: preliminary results.

Journal Article AJR Am J Roentgenol · October 1999 Featured Publication OBJECTIVE: Bronchiolitis obliterans syndrome is the major cause of long-term graft failure in lung transplant recipients and may be partially reversible if diagnosed early and treated. Diagnosis is difficult because findings of transbronchial biopsy are of ... Full text Link to item Cite

Staging non-small cell lung cancer with whole-body PET.

Journal Article Radiology · September 1999 PURPOSE: To compare the accuracies of whole-body 2-[fluorine 18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) and conventional imaging (thoracic computed tomography [CT], bone scintigraphy, and brain CT or magnetic resonance [MR] imagin ... Full text Link to item Cite

Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung--preliminary observations.

Journal Article Radiology · September 1999 Featured Publication Four patients with cystic fibrosis (CF) were examined with combined hyperpolarized helium 3-enhanced and conventional proton magnetic resonance (MR) imaging. After inhalation of the polarized 3He gas, single breath-hold, gradient-echo images (resonant freq ... Full text Link to item Cite

Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax.

Journal Article Radiology · July 1999 PURPOSE: To determine whether contrast material-enhanced helical computed tomography (CT) of the thorax and upper abdomen changes the tumor stage and management compared with nonenhanced helical CT in patients with newly diagnosed lung cancer. MATERIALS AN ... Full text Link to item Cite

Pulmonary cholesterol granulomas in patients with pulmonary artery hypertension: chest radiographic and CT findings.

Journal Article AJR Am J Roentgenol · May 1999 OBJECTIVE: We describe the chest radiographic and CT findings of pulmonary cholesterol granulomas in patients with pulmonary artery hypertension. CONCLUSION: Histopathologic evidence of cholesterol granulomas was found in five (25%) of 20 patients with sev ... Full text Link to item Cite

Hyperpolarized helium-3 magnetic resonance imaging of bronchiolitis obliterans syndrome in lung transplant recipients.

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · March 1, 1999 Link to item Cite

Respiratory viral infections in lung transplant recipients: Radiologic findings with clinical correlation

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · March 1, 1999 Link to item Cite

Lung transplantation for lymphangioleiomyomatosis: role of imaging in the assessment of complications related to the underlying disease.

Journal Article Radiology · February 1999 PURPOSE: To identify the complications and imaging findings related to lymphangioleiomyomatosis (LAM) after lung transplantation. MATERIALS AND METHODS: The authors retrospectively reviewed the clinical histories and imaging studies of 13 patients from fiv ... Full text Link to item Cite

Bronchopericardial fistula after placement of an automatic implantable cardioverter defibrillator: radiographic and CT findings.

Journal Article AJR Am J Roentgenol · February 1999 OBJECTIVE: We describe our experience with bronchopericardial fistula as a complication of infection in patients who have undergone placement of automatic implantable cardioverter defibrillator systems. CONCLUSION: Bronchopericardial fistula should be susp ... Full text Link to item Cite

Opportunistic fungal pneumonia.

Journal Article J Thorac Imaging · January 1999 Opportunistic fungal infection is a common cause of serious morbidity and mortality in immunocompromised patients. These infections occur primarily in patients with chemotherapy-induced neutropenia, acquired immunodeficiency syndrome. or immunosuppression ... Full text Link to item Cite

Malignant pleural effusions: treatment with small-bore-catheter thoracostomy and talc pleurodesis.

Journal Article Radiology · January 1999 Thirty-two patients with a known primary malignancy and a symptomatic malignant pleural effusion underwent small-bore-catheter thoracostomy and talc pleurodesis. Twenty-three patients (72%) had a complete response; four (12%), a partial response; and five ... Full text Link to item Cite

The many faces of pulmonary aspiration.

Journal Article AJR Am J Roentgenol · January 1999 The clinical and radiologic manifestations of aspiration are truly protean. The diagnosis is straightforward in patients with known risk factors and new radiographic findings in dependent portions of lung. However, diagnosis is difficult in patients withou ... Full text Link to item Cite

Pulmonary nontuberculous mycobacterial infection: radiologic manifestations.

Journal Article Radiographics · 1999 The nontuberculous mycobacteria (NTMB) are a group of bacteria that can infect the cervical lymph nodes, skin, soft tissues, and lung. Pulmonary NTMB disease is increasing in prevalence and is most commonly caused by Mycobacterium avium-intracellulare or M ... Full text Link to item Cite

Non-small cell lung cancer: FDG-PET imaging

Journal Article Journal of Thoracic Imaging · January 1, 1999 Positron emission tomography is a clinically useful imaging modality that complements conventional radiologic studies in the evaluation of focal pulmonary opacities, lung cancer staging, tumor recurrence, treatment response, and prognosis. © 1999 Lippincot ... Full text Cite

Bronchial anastomotic complications in lung transplant recipients: virtual bronchoscopy for noninvasive assessment.

Journal Article Radiology · December 1998 PURPOSE: To compare the accuracy of virtual bronchoscopy (VB) with that of axial computed tomography (CT) in the assessment of bronchial anastomotic complications in lung transplant recipients. MATERIALS AND METHODS: Twenty-seven bronchial anastomoses in 1 ... Full text Link to item Cite

Computer aided diagnosis of interstitial lung disease: A texture feature extraction and classification approach

Journal Article Proceedings of SPIE - The International Society for Optical Engineering · December 1, 1998 An approach for the classification of normal or abnormal lung parenchyma from selected regions of interest (ROIs) of chest radiographs is presented for computer aided diagnosis of interstitial lung disease (ILD). The proposed approach uses a feed-forward n ... Full text Cite

Does hyperexpansion of the native lung adversely affect outcome after single lung transplantation for emphysema? Preliminary findings.

Journal Article Acad Radiol · October 1998 RATIONALE AND OBJECTIVES: The authors evaluated the effect of the native emphysematous lung on graft function after single lung transplantation. MATERIALS AND METHODS: Thirty-two patients who underwent single lung transplantation were examined with radiogr ... Full text Link to item Cite

Castleman disease of the thorax: radiologic features with clinical and histopathologic correlation.

Journal Article Radiology · October 1998 PURPOSE: To correlate the radiologic manifestations of thoracic Castleman disease with the clinical and histopathologic features. MATERIALS AND METHODS: The clinical, surgical, and histopathologic records; chest radiographs; and computed tomographic (CT) a ... Full text Link to item Cite

Evaluation of primary pulmonary carcinoid tumors using FDG PET.

Journal Article AJR Am J Roentgenol · May 1998 OBJECTIVE: The purpose of this study was to determine the spectrum of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) findings in patients who have primary pulmonary carcinoid tumors. CONCLUSION: On FDG PET imaging, pulmonary carcinoid ... Full text Link to item Cite

Virtual bronchoscopy for directing transbronchial needle aspiration of hilar and mediastinal lymph nodes: a pilot study.

Journal Article AJR Am J Roentgenol · May 1998 OBJECTIVE: We conducted a preliminary investigation of virtual bronchoscopy as a guide for transbronchial needle aspiration of hilar or mediastinal lymph nodes to assess the usefulness of this technique. CONCLUSION: Virtual bronchoscopic images derived fro ... Full text Link to item Cite

Sclerotherapy for malignant pleural effusions: a prospective randomized trial of bleomycin vs doxycycline with small-bore catheter drainage.

Journal Article Chest · May 1998 BACKGROUND: Malignant pleural effusions are a common problem for patients with metastatic disease. Most patients are treated with tube thoracostomy and sclerotherapy, although there remains no standard approach. The purpose of this study was to compare the ... Full text Link to item Cite

Lentil aspiration pneumonia: radiographic and CT findings.

Journal Article J Comput Assist Tomogr · 1998 Aspiration of leguminous vegetables can cause a granulomatous pneumonitis know as lentil aspiration pneumonia that manifest on radiologic studies with small, poorly defined nodular opacities. We report two cases of lentil aspiration pneumonia that manifest ... Full text Link to item Cite

Evaluation of patients with round atelectasis using 2-[18F]-fluoro-2-deoxy-D-glucose PET.

Journal Article J Comput Assist Tomogr · 1998 PURPOSE: Our goal was to determine the spectrum of 2-[18F]fluoro-2-deoxy-D-glucose (FDG) PET findings in patients with round atelectasis (RA). METHOD: All patients from 1992 to 1997 with radiologic features of RA and FDG-PET scans were evaluated. There wer ... Full text Link to item Cite

Fine needle aspiration of osteogenic sarcoma metastatic to the lung. A report of four cases.

Journal Article Acta Cytol · 1998 BACKGROUND: Osteogenic sarcoma (OGS) is a relatively rare, highly malignant neoplasm of bone with a tendency to metastasize to the lung. Resection of pulmonary metastases in selected instances can increase survival and likelihood of a cure. To date, fine n ... Full text Link to item Cite

Thoracic imaging features of patients with antiphospholipid antibodies.

Journal Article J Comput Assist Tomogr · 1998 PURPOSE: Our aim was to determine the thoracic manifestations of patients with antiphospholipid antibodies (APAs). METHOD: We performed a retrospective review of the clinical records and thoracic imaging studies of 88 patients (63 women, 25 men; mean age 4 ... Full text Link to item Cite

Thoracic FDG PET: state of the art.

Journal Article Radiographics · 1998 The D-glucose analogue 2-(fluorine-18) fluoro-2-deoxy-D-glucose (FDG) is the most commonly used radionuclide in positron emission tomography (PET) of the thorax. Increased glucose metabolism by malignant cells allows physiologic differentiation between ben ... Full text Link to item Cite

Case 5

Journal Article Radiology · January 1, 1998 Full text Cite

Radiologic issues in lung transplantation for end-stage pulmonary disease.

Journal Article AJR Am J Roentgenol · July 1997 Lung transplantation has evolved into an effective therapy for end-stage pulmonary disease. The radiologist has an important role in the management of these patients before and after transplantation. Unfortunately, the radiologic findings of the major comp ... Full text Link to item Cite

Pulmonary mucormycosis: radiologic findings in 32 cases.

Journal Article AJR Am J Roentgenol · June 1997 OBJECTIVE: The purpose of this study was to characterize the radiologic manifestations of pulmonary mucormycosis with clinical and pathologic correlation. MATERIALS AND METHODS: Clinical records, pathology reports, chest radiographs, and CT scans of 32 cas ... Full text Link to item Cite

Evaluation of adrenal masses in patients with bronchogenic carcinoma using 18F-fluorodeoxyglucose positron emission tomography.

Journal Article AJR Am J Roentgenol · May 1997 OBJECTIVE: The purpose of this study was to assess the usefulness of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) when differentiating benign from metastatic adrenal masses in patients with bronchogenic carcinoma. SUBJECTS AND METHO ... Full text Link to item Cite

Telescoping bronchial anastomoses for unilateral or bilateral sequential lung transplantation: CT appearance.

Journal Article Radiology · April 1997 PURPOSE: To determine the computed tomographic (CT) appearance of telescoping bronchial anastomoses. MATERIALS AND METHODS: CT scans obtained in 36 adult patients with 54 telescoping anastomoses (30 right bronchus, 24 left bronchus) were retrospectively re ... Full text Link to item Cite

Hierarchical Markov random field modeling for texture classification in chest radiographs

Journal Article Proceedings of SPIE - The International Society for Optical Engineering · December 1, 1996 A hierarchical Markov random field (MRF) modeling approach is presented for the classification of textures in selected regions of interest (ROIs) of chest radiographs. The procedure integrates possible texture classes and their spatial definition with othe ... Full text Cite

Thoracic FDG PET: State of the art

Journal Article RADIOLOGY · November 1, 1996 Link to item Cite

Apical lung hernia: radiologic findings in six cases.

Journal Article AJR Am J Roentgenol · October 1996 OBJECTIVE: We performed this study to characterize the clinical and radiologic manifestations of apical lung hernias. CONCLUSION: Apical lung hernias typically manifest as unilateral, right-sided air radiolucencies at the thoracic inlet on chest radiograph ... Full text Link to item Cite

The alphabet soup revisited: the chronic interstitial pneumonias in the 1990s.

Journal Article Radiographics · September 1996 Liebow classified the idiopathic interstitial pneumonias as usual (UIP), desquamative (DIP), bronchiolitis obliterans (BIP), lymphoid (LIP), and giant cell (GIP) interstitial pneumonias. This classification was modified to exclude LIP and GIP. UIP, the mos ... Full text Link to item Cite

Complications of lung transplantation: radiologic findings.

Journal Article AJR Am J Roentgenol · June 1996 The first clinically successful lung transplantation was performed in 1983. Since that time, more than 2700 transplants have been recorded by the International Lung Transplant Registry [1]. Lung transplantation is currently limited to patients with endstag ... Full text Link to item Cite

The hepatopulmonary syndrome: radiologic findings in 10 patients.

Journal Article AJR Am J Roentgenol · June 1996 OBJECTIVE: The purpose of this study was to review the radiologic manifestations of the hepatopulmonary syndrome. MATERIALS AND METHODS: We retrospectively reviewed clinical records, chest radiographs, 99m Tc-macroaggregated albumin (MAA) perfusion lung sc ... Full text Link to item Cite

Ambulatory sclerotherapy for malignant pleural effusions.

Journal Article Radiology · April 1996 PURPOSE: To determine the feasibility of ambulatory drainage and sclerotherapy in malignant pleural effusions. MATERIALS AND METHODS: Nineteen consecutive patients with symptomatic malignant pleural effusions were enrolled. None of the patients previously ... Full text Link to item Cite

Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura.

Journal Article Am J Clin Pathol · February 1996 A newly recognized distinctive fibrous soft tissue lesion called "calcifying fibrous pseudotumor" (CFPT) was recently described in the soft tissues of the extremities, trunk, scrotum, groin, neck, or axilla. To date, CFPT has not been described in the pleu ... Full text Link to item Cite

Calcifying fibrous pseudotumor of pleura: radiologic features in three cases.

Journal Article J Comput Assist Tomogr · 1996 PURPOSE: Our goal was to describe the radiologic features of calcifying fibrous pseudotumor (CEPT) of pleura. METHOD: Chest radiographs and CT images of three patients, aged 23-34 years, with pathologically proven CFPT of pleura were reviewed with regard t ... Full text Link to item Cite

Case report. Pericardial hemangioma.

Journal Article J Comput Assist Tomogr · 1996 Hemangiomas are rare cardiac and pericardial neoplasms, with the majority diagnosed incidentally at autopsy. Pericardial hemangiomas typically arise from visceral pericardium, and most are cavernous hemangiomas. They are usually solitary and well circumscr ... Full text Link to item Cite

Assessment of several virtual endoscopy techniques using computed tomography and perspective volume rendering

Journal Article Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) · January 1, 1996 Advanced medical imaging techniques available today, such as CT, MRI, and PET, are capable of producing large quantities of near isotropically-sampled data. These datasets coupled with advanced techniques in Computer graphics can create new ways to explore ... Full text Cite

Chest case of the day. Fibrosing mediastinitis.

Journal Article AJR Am J Roentgenol · July 1995 Full text Link to item Cite

Radiologic manifestations of pulmonary tuberculosis.

Journal Article Radiol Clin North Am · July 1995 In summary, the following points are reemphasized: 1. The chest film is the mainstay in the radiologic evaluation of suspected or proven pulmonary TB. CT is occasionally useful for clarifying confusing findings but has not been conclusively shown to have a ... Link to item Cite

Chest case of the day. Williams-Campbell syndrome.

Journal Article AJR Am J Roentgenol · July 1995 Full text Link to item Cite

Chest case of the day. Hypersensitivity pneumonitis.

Journal Article AJR Am J Roentgenol · July 1995 Full text Link to item Cite

Exploratory thoracotomy for nonresectable lung cancer.

Journal Article Chest · April 1995 We sought to evaluate the effect of new diagnostic modalities on patients explored surgically for inoperable lung cancer. From July 1983 to February 1992, 335 patients underwent thoracotomy for lung cancer. Thirty-three of the 35 patients with nonresectabl ... Full text Link to item Cite

Thoracic mycoses from endemic fungi: radiologic-pathologic correlation.

Journal Article Radiographics · March 1995 The endemic fungi Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides immitis are primary human pathogens whose major portal of entry is the respiratory tract. Their clinical manifestations are categorized as acute, chronic or chronic progre ... Full text Link to item Cite

Thoracic sarcoidosis: radiologic-pathologic correlation.

Journal Article Radiographics · March 1995 Sarcoidosis is a systemic disease of unknown etiology with variable presentation, prognosis, and progression. At diagnosis, about 50% of patients are asymptomatic, 25% complain of cough or dyspnea, and 25% have skin lesions (erythema nodosum, lupus pernio, ... Full text Link to item Cite

Thoracic mycoses from opportunistic fungi: radiologic-pathologic correlation.

Journal Article Radiographics · March 1995 Fungi of the genera Aspergillus, Candida, and Cryptococcus and the class Zygomycetes are the most common causes of thoracic opportunistic mycoses in immunocompromised patients. Candidiasis and zygomycosis usually manifest as severe, often life-threatening, ... Full text Link to item Cite

Chest case of the day

Journal Article American Journal of Roentgenology · January 1, 1995 Cite

Mediastinal hemangioma: radiographic and CT features in 14 patients.

Journal Article Radiology · November 1994 PURPOSE: To characterize the imaging features of mediastinal hemangioma. MATERIALS AND METHODS: The authors retrospectively reviewed chest radiographs and computed tomographic (CT) scans from 14 patients with mediastinal hemangioma. RESULTS: Most mediastin ... Full text Link to item Cite

Mediastinal perigraft seroma: CT and MR imaging.

Journal Article J Thorac Imaging · 1994 We report a patient who developed a perigraft seroma after a modified Blalock-Taussig procedure in which a polytetrafluoroethylene (Gore-tex) graft was used. Computed tomography and magnetic resonance were instrumental in the evaluation of this seroma. ... Full text Link to item Cite

Protein S deficiency: imaging findings.

Journal Article AJR Am J Roentgenol · December 1993 Protein S deficiency is an autosomal-dominant inherited disorder of coagulation associated with spontaneous and recurrent venous thrombosis. Approximately 5% of patients with deep venous thrombosis of the lower extremities who are less than 45 years old ha ... Full text Link to item Cite

Mediastinal bronchogenic cyst: demonstration of a fluid-fluid level at MR imaging.

Journal Article Radiology · February 1993 The appearance of mediastinal bronchogenic cysts at cross-sectional imaging is variable. Intracystic hemorrhage, proteinaceous fluid, or suspended calcium may belie the true cystic nature of the lesion at computed tomography or magnetic resonance (MR) imag ... Full text Link to item Cite

Calcified intrahepatic portal vein thrombus: distinction from intrahepatic choledocholithiasis.

Journal Article J Comput Assist Tomogr · 1992 In a case of calcified intrahepatic portal vein thrombus CT demonstrated a branching calcified intrahepatic mass with peripheral enhancement following dynamic bolus contrast medium administration. The distinction from intrahepatic choledocholithiasis was m ... Full text Link to item Cite

CT and MR imaging of Canavan disease.

Journal Article AJNR Am J Neuroradiol · 1990 Link to item Cite

Leukemic infiltrates of the heart: CT findings.

Journal Article J Comput Assist Tomogr · 1989 Although primary cardiac tumors are rare, metastatic disease to the heart is not uncommon. This is particularly true of the leukemias. Because of increased patient survival, cardiac leukemic infiltrates may assume a larger role in the gamut of leukemic com ... Full text Link to item Cite

IMPLEMENTATION OF ADAPTIVE FILTRATION FOR DIGITAL CHEST IMAGING.

Journal Article Optical Engineering · January 1, 1987 Full text Cite

Histogram-directed processing of digital chest images.

Journal Article Invest Radiol · March 1986 One of the potential advantages of digital chest imaging is the ability to process these images. However, such processing, when uniformly applied to the entire image, is often unsatisfactory due to the different processing requirements of lung field and me ... Full text Link to item Cite

71 HISTOGRAM DIRECTED PROCESSING OF DIGITAL CHEST IMAGES

Journal Article Investigative Radiology · September 1985 Full text Cite

105 Optimization of Adaptive Filtration for Digital Chest Imaging

Journal Article Investigative Radiology · September 1985 Full text Cite