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Rex Monroe McCallum

Professor of Medicine
Medicine, Rheumatology and Immunology
Duke Box 3544, Durham, NC 27710
234 Cooked Creek Pwky., Durham, NC 27713


My main research interests remain Cogan's syndrome, inflammatory eye disease, and vasculitis. I maintain a clinical data base of the greater than 50 patients with Cogan's syndrome that have been evaluated by Dr. Barton F. Haynes and me since 1977. Cogan's syndrome is a syndrome of inflammatory eye disease associated with vestibuloauditory dysfunction that is Menierre's-like. The etiology of this unusual illness is felt to be inflammatory and autoimmune. In addition, I am one of two attendings in the Duke Uveitis Clinic with Dr. Glen Jaffe of ophthalmology. We maintain a clinical data base of all patients evaluated in the clinic. We perform clinical trials of medications and new approaches to treating inflammatory eye disease. We use an number of systemic medicines to treat inflammatory eye diseases and evaluate our results.

I am co-principal investigator for my colleague, Dr. E. William St. Clair, on his rheumatoid arthritis trials.

Key words: Cogan's syndrome, vasculitis, inflammatory eye disease, uveitis, rheumatoid arthritis

Current Appointments & Affiliations

Professor of Medicine · 2022 - Present Medicine, Rheumatology and Immunology, Medicine
Vice-Chair for Faculty Affairs in the Department of Medicine · 2007 - Present Medicine, Clinical Science Departments

Education, Training & Certifications

Vanderbilt University · 1980 M.D.