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Rex Monroe McCallum

Professor of Medicine
Medicine, Rheumatology and Immunology
Duke Box 3544, Durham, NC 27710
234 Cooked Creek Pwky., Durham, NC 27713

Overview


My main research interests remain Cogan's syndrome, inflammatory eye disease, and vasculitis. I maintain a clinical data base of the greater than 50 patients with Cogan's syndrome that have been evaluated by Dr. Barton F. Haynes and me since 1977. Cogan's syndrome is a syndrome of inflammatory eye disease associated with vestibuloauditory dysfunction that is Menierre's-like. The etiology of this unusual illness is felt to be inflammatory and autoimmune. In addition, I am one of two attendings in the Duke Uveitis Clinic with Dr. Glen Jaffe of ophthalmology. We maintain a clinical data base of all patients evaluated in the clinic. We perform clinical trials of medications and new approaches to treating inflammatory eye disease. We use an number of systemic medicines to treat inflammatory eye diseases and evaluate our results.

I am co-principal investigator for my colleague, Dr. E. William St. Clair, on his rheumatoid arthritis trials.


Key words: Cogan's syndrome, vasculitis, inflammatory eye disease, uveitis, rheumatoid arthritis

Current Appointments & Affiliations


Professor of Medicine · 2022 - Present Medicine, Rheumatology and Immunology, Medicine
Vice-Chair for Faculty Affairs in the Department of Medicine · 2007 - Present Medicine, Clinical Science Departments

Recent Publications


Peripheral ulcerative keratitis due to systemic diseases.

Journal Article Curr Opin Ophthalmol · November 1, 2022 PURPOSE OF REVIEW: To discuss peripheral ulcerative keratitis, with a focus on the evaluation and management of associated systemic diseases. RECENT FINDINGS: Peripheral ulcerative keratitis (PUK) is a sight-threatening condition that is often defined by t ... Full text Link to item Cite

Development of a quality improvement program in a department of ophthalmology.

Journal Article Br J Ophthalmol · December 2013 OBJECTIVE: To design and implement a quality improvement (QI) programme in an academic department of ophthalmology. DESIGN: The six core competencies of the Accreditation Council for Graduate Medical Education serve as the model for this programme in an in ... Full text Link to item Cite

Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis.

Journal Article Ophthalmology · July 2005 PURPOSE: To investigate the safety and efficacy of a fluocinolone acetonide intravitreal implant in the treatment of noninfectious posterior uveitis. DESIGN: Noncomparative interventional case series, dose randomized, dose masked, prospective. PARTICIPANTS ... Full text Link to item Cite
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Education, Training & Certifications


Vanderbilt University · 1980 M.D.