Scholars@Duke
Rex Monroe McCallum

Rex Monroe McCallum

Professor of Medicine
Medicine, Rheumatology and Immunology
rmmcal@duke.edu
Duke Box 3544, Durham, NC 27710
234 Cooked Creek Pwky., Durham, NC 27713

Selected Publications

Peripheral ulcerative keratitis due to systemic diseases.

Journal Article Curr Opin Ophthalmol · November 1, 2022 PURPOSE OF REVIEW: To discuss peripheral ulcerative keratitis, with a focus on the evaluation and management of associated systemic diseases. RECENT FINDINGS: Peripheral ulcerative keratitis (PUK) is a sight-threatening condition that is often defined by t ... Full text Link to item Cite

Development of a quality improvement program in a department of ophthalmology.

Journal Article Br J Ophthalmol · December 2013 OBJECTIVE: To design and implement a quality improvement (QI) programme in an academic department of ophthalmology. DESIGN: The six core competencies of the Accreditation Council for Graduate Medical Education serve as the model for this programme in an in ... Full text Link to item Cite

Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis.

Journal Article Ophthalmology · July 2005 PURPOSE: To investigate the safety and efficacy of a fluocinolone acetonide intravitreal implant in the treatment of noninfectious posterior uveitis. DESIGN: Noncomparative interventional case series, dose randomized, dose masked, prospective. PARTICIPANTS ... Full text Link to item Cite

Demographic-related variations in posterior segment ocular sarcoidosis.

Journal Article Ophthalmology · February 2004 OBJECTIVE: To compare the frequency of posterior segment involvement (PSI), the prevalence of specific posterior segment signs, and visual acuity in ocular sarcoidosis by patient race, sex, and age. DESIGN: Retrospective, cross-sectional observational stud ... Full text Link to item Cite

Methotrexate treatment for sarcoid-associated panuveitis.

Journal Article Ophthalmology · January 1999 OBJECTIVE: To determine the safety and efficacy of low-dose methotrexate (MTX) for sarcoid-associated panuveitis. DESIGN: Retrospective noncomparative case series. PARTICIPANTS: Twenty eyes from 11 patients were analyzed. Eight patients had sarcoidosis. Th ... Full text Link to item Cite

Cogan's syndrome.

Journal Article Curr Opin Rheumatol · January 1999 Work originating in the 1940s led to the characterization of a rare, chronic inflammatory disorder with a unique predilection for the cornea and vestibuloauditory apparatus, now called Cogan's syndrome (CS) after the ophthalmologist who first described it. ... Full text Link to item Cite

Uveitis in the southeastern United States.

Journal Article Curr Eye Res · September 1997 PURPOSE: Previous epidemiologic studies of uveitis have focused on predominantly Caucasian populations, and none have been based in the Southeast. We analyzed the epidemiology of uveitis among a referral population with a high percentage of African America ... Full text Link to item Cite

Arthritis syndromes associated with human T cell lymphotropic virus type I infection.

Journal Article Med Clin North Am · January 1997 Arthritis syndromes occur associated with HTLV-I infection both in the presence and in the absence of clinical ATL, and polyarthritis may be the presenting manifestation of HTLV-I-associated ATL. In both clinical settings, HTLV-I-infected T cells home to a ... Full text Link to item Cite

Transcranial doppler sonography to monitor cerebral vasculitis.

Journal Article J Rheumatol · March 1996 We describe a patient with cerebral vasculitis treated with prednisone and cyclophosphamide and followed by serial transcranial Doppler sonography and arteriography. Proximal cerebral angiographic abnormalities correlated with transcranial Doppler abnormal ... Link to item Cite

Changing concepts in pathophysiology of the vasculitides.

Journal Article Curr Opin Rheumatol · January 1994 Vasculitis is a clinicopathologic process that involves inflammation and necrosis of blood vessels, resulting in a wide range of clinical diseases. The pathogenesis of vasculitis has been attributed to immunologic mechanisms, including immune complexes, ce ... Full text Link to item Cite

Analysis of corneal and conjunctival microenvironments using monoclonal antibodies.

Journal Article Invest Ophthalmol Vis Sci · April 1993 PURPOSE: The authors phenotypically compared epithelial and nonepithelial components of human corneal and conjunctival microenvironments using a panel of monoclonal antibody reagents that included markers of epithelial cell maturation, markers of mesoderma ... Link to item Cite

Cyclosporin A therapy for Wegener's granulomatosis.

Journal Article Adv Exp Med Biol · 1993 Five patients with active Wegener's granulomatosis were treated with the immunosuppressive agent Cyclosporin A, along with low dose prednisone. All five patients had previously taken cyclophosphamide, but further treatment with this agent was not desired, ... Full text Link to item Cite

Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis.

Journal Article Arthritis Rheum · November 1991 The hyaluronate receptor (CD44) molecule is a multifunctional cell surface protein involved in T cell activation, monocyte cytokine release, fibroblast locomotion, and lymphocyte binding to high endothelial venules. To study the roles CD44 molecules play i ... Full text Link to item Cite

Rheumatologic manifestations of cancer.

Journal Article Med Clin North Am · March 1986 A variety of musculoskeletal syndromes have been described in association with malignancy. The majority of such descriptions have dealt with the connective tissue disorder as a paraneoplastic syndrome, frequently the presenting feature of an otherwise occu ... Full text Link to item Cite