Cyclosporin A therapy for Wegener's granulomatosis.
Publication
, Journal Article
Allen, NB; Caldwell, DS; Rice, JR; McCallum, RM
Published in: Adv Exp Med Biol
1993
Five patients with active Wegener's granulomatosis were treated with the immunosuppressive agent Cyclosporin A, along with low dose prednisone. All five patients had previously taken cyclophosphamide, but further treatment with this agent was not desired, either due to patient choice, drug toxicity or malignancy. In initial doses of up to 5mg/kg/day, CyA showed efficacy but when lowered to 1-2mg/kg/day, mild disease flares occurred. CyA may provide an alternative to traditional therapy in selected patients with WG.
Duke Scholars
Published In
Adv Exp Med Biol
DOI
ISSN
0065-2598
Publication Date
1993
Volume
336
Start / End Page
473 / 476
Location
United States
Related Subject Headings
- Prednisone
- Middle Aged
- Male
- Humans
- Granulomatosis with Polyangiitis
- General & Internal Medicine
- Female
- Drug Therapy, Combination
- Cyclosporine
- Adult
Citation
APA
Chicago
ICMJE
MLA
NLM
Allen, N. B., Caldwell, D. S., Rice, J. R., & McCallum, R. M. (1993). Cyclosporin A therapy for Wegener's granulomatosis. Adv Exp Med Biol, 336, 473–476. https://doi.org/10.1007/978-1-4757-9182-2_85
Allen, N. B., D. S. Caldwell, J. R. Rice, and R. M. McCallum. “Cyclosporin A therapy for Wegener's granulomatosis.” Adv Exp Med Biol 336 (1993): 473–76. https://doi.org/10.1007/978-1-4757-9182-2_85.
Allen NB, Caldwell DS, Rice JR, McCallum RM. Cyclosporin A therapy for Wegener's granulomatosis. Adv Exp Med Biol. 1993;336:473–6.
Allen, N. B., et al. “Cyclosporin A therapy for Wegener's granulomatosis.” Adv Exp Med Biol, vol. 336, 1993, pp. 473–76. Pubmed, doi:10.1007/978-1-4757-9182-2_85.
Allen NB, Caldwell DS, Rice JR, McCallum RM. Cyclosporin A therapy for Wegener's granulomatosis. Adv Exp Med Biol. 1993;336:473–476.
Published In
Adv Exp Med Biol
DOI
ISSN
0065-2598
Publication Date
1993
Volume
336
Start / End Page
473 / 476
Location
United States
Related Subject Headings
- Prednisone
- Middle Aged
- Male
- Humans
- Granulomatosis with Polyangiitis
- General & Internal Medicine
- Female
- Drug Therapy, Combination
- Cyclosporine
- Adult