Meira Epplein
Professor in Population Health Sciences
Meira Epplein is a cancer epidemiologist interested in modifiable risk factors in under-served populations. She is a Professor in Population Health Sciences and in Medicine, and currently serves as Co-Leader of the Cancer Risk, Detection, and Interception research program of the Duke Cancer Institute. Previously, she was a tenured faculty member at Vanderbilt University Medical Center, after two years as a post-doctoral fellow with the Multiethnic Cohort Study at the University of Hawaii. Prior to earning her PhD in epidemiology from the University of Washington, she completed an MA in international studies, and spent five years as a program officer for the Asian research think tank, the National Bureau of Asian Research.
Dr. Epplein’s research program is focused on the prevention of infection-associated cancers, and has specifically centered around the bacteria Helicobacter pylori, a spiral, gram-negative bacterium that infects approximately 50% of the world’s population, and is the leading carcinogenic infectious agent according to the International Agency for Research on Cancer. Her research seeks to determine the most toxigenic forms of the bacteria so to identify the highest risk populations which can then be targeted for antibiotic therapy, which has been shown to be effective for risk reduction. At the same time, she is committed to furthering our understanding of the co-factors involved in both H. pylori-associated disease risk and benefit, as the bacteria has inhabited the stomachs of humans for over 100,000 years, and so very likely also confers certain biological advantages to its hosts.
She has been PI of four grants from the NIH focusing on a greater understanding of the diversity of Helicobacter pylori and host response to infection and the association with gastrointestinal cancers. Through this work she has established the importance of the understanding of H. pylori as a heterogeneous exposure, identifying bacteria-specific blood biomarkers of increased cancer risk, and finding that these biomarkers interact with other potentially modifiable factors such as diet and aspirin use, in their association with the development of gastric cancer. She has also found significant differences in H. pylori prevalence and antibody response by self-reported race within the US, and have begun local initiatives to understand the prevalence of H. pylori in the community and clinic and to move towards eradication trials for high-risk individuals.
Area of expertise: Epidemiology
Current Appointments & Affiliations
- Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2023
- Professor in Medicine, Medicine, Medical Oncology, Medicine 2023
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017
Contact Information
- 2424 Erwin Road, Suite 602, Durham, NC 27705
- DUMC 2715, Durham, NC 27710
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meira.epplein@duke.edu
(919) 668-0766
- Background
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Education, Training, & Certifications
- Ph.D., University of Washington 2007
- M.S., University of Washington 2005
- M.A., University of Washington 1997
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Previous Appointments & Affiliations
- Associate Professor in Medicine, Medicine, Medical Oncology, Medicine 2020 - 2022
- Associate Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2021 - 2022
- Associate Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2017 - 2020
- Associate Professor in Medicine, Medicine, Medical Oncology, Medicine 2017 - 2020
- Instructor in the Department of Population Health Sciences, Population Health Sciences, Basic Science Departments 2017
- Instructor, Temporary in the Department ofMedicine, Medicine, Medical Oncology, Medicine 2017
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Leadership & Clinical Positions at Duke
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Co-Leader, Cancer Risk, Detection, and Interception Research Program, Duke Cancer Institute, 2021-present
Co-Leader, Cancer Control and Population Sciences, Duke Cancer Institute, 2017-2021
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Co-Leader, Cancer Risk, Detection, and Interception Research Program, Duke Cancer Institute, 2021-present
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Academic Positions Outside Duke
- Adjunct Associate Professor of Medicine, Vanderbilt University Medical Center. 2017
- Recognition
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In the News
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SEP 6, 2022 School of Medicine Magnify -
APR 15, 2022 School of Medicine Magnify -
MAY 21, 2019 Duke Cancer Institute
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- Research
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Selected Grants
- Delineating the underlying reasons for the racial disparity in gastric cancer incidence in the United States awarded by National Institutes of Health 2022 - 2027
- Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program awarded by National Institutes of Health 2022 - 2027
- Duke Training Grant in Digestive Diseases and Nutrition awarded by National Institutes of Health 1988 - 2027
- DIRECT - Diversifying Research and Experiential Learning in Cancer Training awarded by Emerson Collective 2021 - 2024
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
- Helicobacter pylori blood biomarker for gastric cancer risk in East Asia awarded by National Institutes of Health 2017 - 2020
- Helicobacter pylori protein-specific antibodies and colorectal cancer risk awarded by National Institutes of Health 2017 - 2020
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External Relationships
- American Association for Cancer Research
- National Institutes of Health
- Stand Up To Cancer
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Butt, Julia, and Meira Epplein. “How do global trends in Helicobacter pylori prevalence inform prevention planning?” Lancet Gastroenterol Hepatol 8, no. 6 (June 2023): 498–99. https://doi.org/10.1016/S2468-1253(23)00101-2.Full Text Link to Item
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Alagesan, Priya, Jessica C. Goodwin, Katherine S. Garman, and Meira Epplein. “Cancer Progress and Priorities: Gastric Cancer.” Cancer Epidemiol Biomarkers Prev 32, no. 4 (April 3, 2023): 473–86. https://doi.org/10.1158/1055-9965.EPI-22-0994.Full Text Link to Item
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Huang, Robert J., Monika Laszkowska, Haejin In, Joo Ha Hwang, and Meira Epplein. “Controlling Gastric Cancer in a World of Heterogeneous Risk.” Gastroenterology 164, no. 5 (April 2023): 736–51. https://doi.org/10.1053/j.gastro.2023.01.018.Full Text Link to Item
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Huang, Robert J., Meira Epplein, Chisato Hamashima, Il Ju Choi, Eunjung Lee, Dennis Deapen, Yanghee Woo, et al. “An Approach to the Primary and Secondary Prevention of Gastric Cancer in the United States.” Clin Gastroenterol Hepatol 20, no. 10 (October 2022): 2218-2228.e2. https://doi.org/10.1016/j.cgh.2021.09.039.Full Text Link to Item
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Butt, Julia, Matti Lehtinen, Hanna Öhman, Tim Waterboer, and Meira Epplein. “Association of Helicobacter pylori and Autoimmune Gastritis With Stomach Cancer in a Cohort of Young Finnish Women.” Gastroenterology 163, no. 1 (July 2022): 305-307.e4. https://doi.org/10.1053/j.gastro.2022.03.012.Full Text Link to Item
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In, Haejin, Srawani Sarkar, Jessica Ward, Patricia Friedmann, Michael Parides, Julie Yang, and Meira Epplein. “Serum Pepsinogen as a Biomarker for Gastric Cancer in the United States: A Nested Case-Control Study Using the PLCO Cancer Screening Trial Data.” Cancer Epidemiol Biomarkers Prev 31, no. 7 (July 1, 2022): 1426–32. https://doi.org/10.1158/1055-9965.EPI-21-1328.Full Text Link to Item
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Murphy, John D., Andrew F. Olshan, Feng-Chang Lin, Melissa A. Troester, Hazel B. Nichols, Julia Butt, You-Lin Qiao, et al. “A Predictive Model of Noncardia Gastric Adenocarcinoma Risk Using Antibody Response to Helicobacter pylori Proteins and Pepsinogen.” Cancer Epidemiol Biomarkers Prev 31, no. 4 (April 1, 2022): 811–20. https://doi.org/10.1158/1055-9965.EPI-21-0869.Full Text Link to Item
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Kayamba, Violet, Julia Butt, Matthew Gordon Varga, Aaron Shibemba, Maria Blanca Piazuelo, Keith Tucker Wilson, Kanekwa Zyambo, et al. “Serum antibodies to selected Helicobacter pylori antigens are associated with active gastritis in patients seen at the University Teaching Hospital in Lusaka, Zambia.” Malawi Med J 34, no. 1 (March 2022): 17–24. https://doi.org/10.4314/mmj.v34i1.4.Full Text Link to Item
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Brown, HannahSofia, Sarah Cantrell, Helen Tang, Meira Epplein, and Katherine S. Garman. “Racial Differences in Helicobacter pylori Prevalence in the US: A Systematic Review.” Gastro Hep Adv 1, no. 5 (2022): 857–68. https://doi.org/10.1016/j.gastha.2022.06.001.Full Text Link to Item
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Lo, Chun-Han, William J. Blot, Lauren R. Teras, Kala Visvanathan, Loïc Le Marchand, Christopher A. Haiman, Yu Chen, et al. “Prediagnostic Antibody Responses to Fusobacterium nucleatum Proteins Are Not Associated with Risk of Colorectal Cancer in a Large U.S. Consortium.” Cancer Epidemiol Biomarkers Prev 30, no. 6 (June 2021): 1279–82. https://doi.org/10.1158/1055-9965.EPI-20-1471.Full Text Link to Item
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Aquilina, Sydney R., Martha J. Shrubsole, Julia Butt, Maureen Sanderson, David G. Schlundt, Mekeila C. Cook, and Meira Epplein. “Adverse childhood experiences and adult diet quality.” J Nutr Sci 10 (2021): e95. https://doi.org/10.1017/jns.2021.85.Full Text Link to Item
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Varga, Matthew G., Cecily R. Wood, Julia Butt, Mackenzie E. Ryan, Wei-Cheng You, Kaifeng Pan, Tim Waterboer, Meira Epplein, and Carrie L. Shaffer. “Immunostimulatory membrane proteins potentiate H. pylori-induced carcinogenesis by enabling CagA translocation.” Gut Microbes 13, no. 1 (2021): 1–13. https://doi.org/10.1080/19490976.2020.1862613.Full Text Link to Item
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Butt, Julia, William J. Blot, Kala Visvanathan, Loïc Le Marchand, Lynne R. Wilkens, Yu Chen, Howard D. Sesso, et al. “Auto-antibodies to p53 and the Subsequent Development of Colorectal Cancer in a U.S. Prospective Cohort Consortium.” Cancer Epidemiol Biomarkers Prev 29, no. 12 (December 2020): 2729–34. https://doi.org/10.1158/1055-9965.EPI-20-0780.Full Text Link to Item
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Epplein, Meira, Loïc Le Marchand, Timothy L. Cover, Mingyang Song, William J. Blot, Richard M. Peek, Lauren R. Teras, et al. “Association of Combined Sero-Positivity to Helicobacter pylori and Streptococcus gallolyticus with Risk of Colorectal Cancer.” Microorganisms 8, no. 11 (October 30, 2020). https://doi.org/10.3390/microorganisms8111698.Full Text Link to Item
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Huang, Robert J., Howard Koh, Joo Ha Hwang, and Joo Ha Summit Leaders. “A Summary of the 2020 Gastric Cancer Summit at Stanford University.” Gastroenterology 159, no. 4 (October 2020): 1221–26. https://doi.org/10.1053/j.gastro.2020.05.100.Full Text Link to Item
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Varga, Matthew G., Julia Butt, William J. Blot, Loïc Le Marchand, Christopher A. Haiman, Yu Chen, Sylvia Wassertheil-Smoller, et al. “Racial Differences in Helicobacter pylori CagA Sero-prevalence in a Consortium of Adult Cohorts in the United States.” Cancer Epidemiol Biomarkers Prev 29, no. 10 (October 2020): 2084–92. https://doi.org/10.1158/1055-9965.EPI-20-0525.Full Text Link to Item
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Crankshaw, Sydnee, Julia Butt, Jennifer M. Gierisch, Nadine J. Barrett, Sabrena Mervin-Blake, Kevin Oeffinger, Steven Patierno, Valarie Worthy, Ronald Godbee, and Meira Epplein. “The Durham Initiative for Stomach Health (DISH): a pilot community-based Helicobacter pylori education and screening study.” Bmc Gastroenterol 20, no. 1 (August 6, 2020): 261. https://doi.org/10.1186/s12876-020-01405-w.Full Text Link to Item
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Jang, Jieun, Tianyi Wang, Hui Cai, Fei Ye, Gwen Murphy, Taichi Shimazu, Philip R. Taylor, et al. “The U-shaped association between body mass index and gastric cancer risk in the Helicobacter pylori Biomarker Cohort Consortium: A nested case-control study from eight East Asian cohort studies.” Int J Cancer 147, no. 3 (August 1, 2020): 777–84. https://doi.org/10.1002/ijc.32790.Full Text Link to Item
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Butt, Julia, William J. Blot, Martha J. Shrubsole, Tim Waterboer, Michael Pawlita, and Meira Epplein. “Differences in antibody levels to H. pylori virulence factors VacA and CagA among African Americans and whites in the Southeast USA.” Cancer Causes Control 31, no. 6 (June 2020): 601–6. https://doi.org/10.1007/s10552-020-01295-z.Full Text Link to Item
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Butt, Julia, William J. Blot, Martha J. Shrubsole, Matthew G. Varga, Laura H. Hendrix, Sydnee Crankshaw, Tim Waterboer, Michael Pawlita, and Meira Epplein. “Performance of multiplex serology in discriminating active vs past Helicobacter pylori infection in a primarily African American population in the southeastern United States.” Helicobacter 25, no. 1 (February 2020): e12671. https://doi.org/10.1111/hel.12671.Full Text Link to Item
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Butt, Julia, and Meira Epplein. “Helicobacter pylori and colorectal cancer-A bacterium going abroad?” Plos Pathog 15, no. 8 (August 2019): e1007861. https://doi.org/10.1371/journal.ppat.1007861.Full Text Link to Item
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Butt, Julia, Matthew G. Varga, and Meira Epplein. “Reply.” Gastroenterology 156, no. 8 (June 2019): 2356. https://doi.org/10.1053/j.gastro.2019.04.040.Full Text Link to Item
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Epplein, Meira, Julia Butt, Yang Zhang, Laura H. Hendrix, Christian C. Abnet, Gwen Murphy, Wei Zheng, et al. “Validation of a Blood Biomarker for Identification of Individuals at High Risk for Gastric Cancer.” Cancer Epidemiol Biomarkers Prev 27, no. 12 (December 2018): 1472–79. https://doi.org/10.1158/1055-9965.EPI-18-0582.Full Text Link to Item
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Varga, Matthew G., Hui Cai, Tim Waterboer, Gwen Murphy, Taichi Shimazu, Phil R. Taylor, You-Lin Qiao, et al. “Epstein-Barr Virus Antibody Titers Are Not Associated with Gastric Cancer Risk in East Asia.” Dig Dis Sci 63, no. 10 (October 2018): 2765–72. https://doi.org/10.1007/s10620-018-5154-9.Full Text Link to Item
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Butt, Julia, William J. Blot, Lauren R. Teras, Kala Visvanathan, Loïc Le Marchand, Christopher A. Haiman, Yu Chen, et al. “Antibody Responses to Streptococcus Gallolyticus Subspecies Gallolyticus Proteins in a Large Prospective Colorectal Cancer Cohort Consortium.” Cancer Epidemiol Biomarkers Prev 27, no. 10 (October 2018): 1186–94. https://doi.org/10.1158/1055-9965.EPI-18-0249.Full Text Link to Item
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Varga, Matthew G., Tianyi Wang, Hui Cai, Yong-Bing Xiang, Yu-Tang Gao, Bu-Tian Ji, Michael Pawlita, et al. “Helicobacter pylori Blood Biomarkers and Gastric Cancer Survival in China.” Cancer Epidemiol Biomarkers Prev 27, no. 3 (March 2018): 342–44. https://doi.org/10.1158/1055-9965.EPI-17-1084.Full Text Link to Item
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Wang, Tianyi, Hui Cai, Wei Zheng, Angelika Michel, Michael Pawlita, Ginger Milne, Yong-Bing Xiang, et al. “A Prospective Study of Urinary Prostaglandin E2 Metabolite, Helicobacter pylori Antibodies, and Gastric Cancer Risk.” Clin Infect Dis 64, no. 10 (May 15, 2017): 1380–86. https://doi.org/10.1093/cid/cix106.Full Text Link to Item
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Wang, Tianyi, Hui Cai, Shizuka Sasazuki, Shoichiro Tsugane, Wei Zheng, Eo Rin Cho, Sun Ha Jee, et al. “Fruit and vegetable consumption, Helicobacter pylori antibodies, and gastric cancer risk: A pooled analysis of prospective studies in China, Japan, and Korea.” Int J Cancer 140, no. 3 (February 1, 2017): 591–99. https://doi.org/10.1002/ijc.30477.Full Text Link to Item
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Cai, Hui, Fei Ye, Angelika Michel, Gwen Murphy, Shizuka Sasazuki, Philip R. Taylor, You-Lin Qiao, et al. “Helicobacter pylori blood biomarker for gastric cancer risk in East Asia.” Int J Epidemiol 45, no. 3 (June 2016): 774–81. https://doi.org/10.1093/ije/dyw078.Full Text Link to Item
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Xu, Hong-Li, Yu-Ting Tan, Meira Epplein, Hong-Lan Li, Jing Gao, Yu-Tang Gao, Wei Zheng, Xiao-Ou Shu, and Yong-Bing Xiang. “Population-based cohort studies of type 2 diabetes and stomach cancer risk in Chinese men and women.” Cancer Sci 106, no. 3 (March 2015): 294–98. https://doi.org/10.1111/cas.12597.Full Text Link to Item
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Epplein, Meira, Roberd M. Bostick, Lina Mu, Shuji Ogino, Dejana Braithwaite, and Peter A. Kanetsky. “Challenges and opportunities in international molecular cancer prevention research: An ASPO Molecular Epidemiology and the Environment and International Cancer Prevention Interest Groups Report.” Cancer Epidemiol Biomarkers Prev 23, no. 11 (November 2014): 2613–17. https://doi.org/10.1158/1055-9965.EPI-14-0848.Full Text Link to Item
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Epplein, Meira, Raymond F. Burk, Qiuyin Cai, Margaret K. Hargreaves, and William J. Blot. “A prospective study of plasma Selenoprotein P and lung cancer risk among low-income adults.” Cancer Epidemiol Biomarkers Prev 23, no. 7 (July 2014): 1238–44. https://doi.org/10.1158/1055-9965.EPI-13-1308.Full Text Link to Item
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Epplein, Meira, Richard M. Peek, and William J. Blot. “Helicobacter pylori Biomarkers and Risk of Colorectal Oncogenesis--Response.” Cancer Epidemiol Biomarkers Prev 23, no. 2 (February 2014): 366. https://doi.org/10.1158/1055-9965.EPI-13-1191.Full Text Link to Item
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Epplein, Meira, Wei Zheng, Honglan Li, Richard M. Peek, Pelayo Correa, Jing Gao, Angelika Michel, et al. “Diet, Helicobacter pylori strain-specific infection, and gastric cancer risk among Chinese men.” Nutr Cancer 66, no. 4 (2014): 550–57. https://doi.org/10.1080/01635581.2014.894096.Full Text Link to Item
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Epplein, Meira, Yong-Bing Xiang, Qiuyin Cai, Richard M. Peek, Honglan Li, Pelayo Correa, Jing Gao, et al. “Circulating cytokines and gastric cancer risk.” Cancer Causes Control 24, no. 12 (December 2013): 2245–50. https://doi.org/10.1007/s10552-013-0284-z.Full Text Link to Item
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Epplein, Meira, Michael Pawlita, Angelika Michel, Richard M. Peek, Qiuyin Cai, and William J. Blot. “Helicobacter pylori protein-specific antibodies and risk of colorectal cancer.” Cancer Epidemiol Biomarkers Prev 22, no. 11 (November 2013): 1964–74. https://doi.org/10.1158/1055-9965.EPI-13-0702.Full Text Link to Item
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Kweon, Sun-Seog, Xiao-Ou Shu, Yongbing Xiang, Hui Cai, Gong Yang, Bu-Tian Ji, Honglan Li, Yu-Tang Gao, Wei Zheng, and Meira Epplein. “Intake of specific nonfermented soy foods may be inversely associated with risk of distal gastric cancer in a Chinese population.” J Nutr 143, no. 11 (November 2013): 1736–42. https://doi.org/10.3945/jn.113.177675.Full Text Link to Item
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Epplein, Meira, Wei Zheng, Yong-Bing Xiang, Richard M. Peek, Honglan Li, Pelayo Correa, Jing Gao, et al. “Prospective study of Helicobacter pylori biomarkers for gastric cancer risk among Chinese men.” Cancer Epidemiol Biomarkers Prev 21, no. 12 (December 2012): 2185–92. https://doi.org/10.1158/1055-9965.EPI-12-0792-T.Full Text Link to Item
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Epplein, Meira, Sarah S. Cohen, Jennifer S. Sonderman, Wei Zheng, Scott M. Williams, William J. Blot, and Lisa B. Signorello. “Neighborhood socio-economic characteristics, African ancestry, and Helicobacter pylori sero-prevalence.” Cancer Causes Control 23, no. 6 (June 2012): 897–906. https://doi.org/10.1007/s10552-012-9960-7.Full Text Link to Item
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Nomura, Abraham M. Y., Lynne R. Wilkens, Brian E. Henderson, Meira Epplein, and Laurence N. Kolonel. “The association of cigarette smoking with gastric cancer: the multiethnic cohort study.” Cancer Causes Control 23, no. 1 (January 2012): 51–58. https://doi.org/10.1007/s10552-011-9854-0.Full Text Link to Item
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Epplein, Meira, Lisa B. Signorello, Wei Zheng, Qiuyin Cai, Margaret K. Hargreaves, Angelika Michel, Michael Pawlita, Jay H. Fowke, Pelayo Correa, and William J. Blot. “Helicobacter pylori prevalence and circulating micronutrient levels in a low-income United States population.” Cancer Prev Res (Phila) 4, no. 6 (June 2011): 871–78. https://doi.org/10.1158/1940-6207.CAPR-10-0398.Full Text Link to Item
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Epplein, Meira, Lisa B. Signorello, Wei Zheng, Richard M. Peek, Angelika Michel, Scott M. Williams, Michael Pawlita, Pelayo Correa, Qiuyin Cai, and William J. Blot. “Race, African ancestry, and Helicobacter pylori infection in a low-income United States population.” Cancer Epidemiol Biomarkers Prev 20, no. 5 (May 2011): 826–34. https://doi.org/10.1158/1055-9965.EPI-10-1258.Full Text Link to Item
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Epplein, Meira, Ying Zheng, Wei Zheng, Zhi Chen, Kai Gu, David Penson, Wei Lu, and Xiao-Ou Shu. “Quality of life after breast cancer diagnosis and survival.” J Clin Oncol 29, no. 4 (February 1, 2011): 406–12. https://doi.org/10.1200/JCO.2010.30.6951.Full Text Link to Item
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Piazuelo, M Blanca, Meira Epplein, and Pelayo Correa. “Gastric cancer: an infectious disease.” Infect Dis Clin North Am 24, no. 4 (December 2010): 853–vii. https://doi.org/10.1016/j.idc.2010.07.010.Full Text Link to Item
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Epplein, Meira, Xiao-Ou Shu, Yong-Bing Xiang, Wong-Ho Chow, Gong Yang, Hong-Lan Li, Bu-Tian Ji, Hui Cai, Yu-Tang Gao, and Wei Zheng. “Fruit and vegetable consumption and risk of distal gastric cancer in the Shanghai Women's and Men's Health studies.” Am J Epidemiol 172, no. 4 (August 15, 2010): 397–406. https://doi.org/10.1093/aje/kwq144.Full Text Link to Item
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Reed, Susan D., Katherine M. Newton, Rochelle L. Garcia, Kimberly H. Allison, Lynda F. Voigt, C Diana Jordan, Meira Epplein, et al. “Complex hyperplasia with and without atypia: clinical outcomes and implications of progestin therapy.” Obstet Gynecol 116, no. 2 Pt 1 (August 2010): 365–73. https://doi.org/10.1097/AOG.0b013e3181e93330.Full Text Link to Item
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Epplein, Meira, Rachel Novotny, Yihe Daida, Vinutha Vijayadeva, Alvin T. Onaka, and Loïc Le Marchand. “Association of maternal and intrauterine characteristics with age at menarche in a multiethnic population in Hawaii.” Cancer Causes Control 21, no. 2 (February 2010): 259–68. https://doi.org/10.1007/s10552-009-9457-1.Full Text Link to Item
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Epplein, Meira, Abraham M. Y. Nomura, Lynne R. Wilkens, Brian E. Henderson, and Laurence N. Kolonel. “Nonsteroidal antiinflammatory drugs and risk of gastric adenocarcinoma: the multiethnic cohort study.” Am J Epidemiol 170, no. 4 (August 15, 2009): 507–14. https://doi.org/10.1093/aje/kwp162.Full Text Link to Item
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Epplein, Meira, Adrian A. Franke, Robert V. Cooney, J Steven Morris, Lynne R. Wilkens, Marc T. Goodman, Suzanne P. Murphy, Brian E. Henderson, Laurence N. Kolonel, and Loïc Le Marchand. “Association of plasma micronutrient levels and urinary isoprostane with risk of lung cancer: the multiethnic cohort study.” Cancer Epidemiol Biomarkers Prev 18, no. 7 (July 2009): 1962–70. https://doi.org/10.1158/1055-9965.EPI-09-0003.Full Text Link to Item
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Reed, S. D., L. F. Voigt, K. M. Newton, R. H. Garcia, K. H. Allison, M. Epplein, D. Jordan, E. Swisher, and N. S. Weiss. “Progestin therapy of complex endometrial hyperplasia with and without atypia.” Obstetrical and Gynecological Survey 64, no. 6 (June 1, 2009): 382–83. https://doi.org/10.1097/01.ogx.0000349785.20763.6d.Full Text
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Reed, Susan D., Katherine M. Newton, Walter L. Clinton, Meira Epplein, Rochelle Garcia, Kimberly Allison, Lynda F. Voigt, and Noel S. Weiss. “Incidence of endometrial hyperplasia.” Am J Obstet Gynecol 200, no. 6 (June 2009): 678.e1-678.e6. https://doi.org/10.1016/j.ajog.2009.02.032.Full Text Link to Item
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Reed, Susan D., Linda F. Voigt, Katherine M. Newton, Rochelle H. Garcia, H Kimberly Allison, Meira Epplein, Diana Jordan, Elizabeth Swisher, and Noel S. Weiss. “Progestin therapy of complex endometrial hyperplasia with and without atypia.” Obstet Gynecol 113, no. 3 (March 2009): 655–62. https://doi.org/10.1097/AOG.0b013e318198a10a.Full Text Link to Item
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Epplein, Meira, Lynne R. Wilkens, Maarit Tiirikainen, Marcin Dyba, Fung-Lung Chung, Marc T. Goodman, Suzanne P. Murphy, Brian E. Henderson, Laurence N. Kolonel, and Loïc Le Marchand. “Urinary isothiocyanates; glutathione S-transferase M1, T1, and P1 polymorphisms; and risk of colorectal cancer: the Multiethnic Cohort Study.” Cancer Epidemiol Biomarkers Prev 18, no. 1 (January 2009): 314–20. https://doi.org/10.1158/1055-9965.EPI-08-0627.Full Text Link to Item
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Epplein, Meira, Susan D. Reed, Lynda F. Voigt, Katherine M. Newton, Victoria L. Holt, and Noel S. Weiss. “Endometrial hyperplasia risk in relation to recent use of oral contraceptives and hormone therapy.” Ann Epidemiol 19, no. 1 (January 2009): 1–7. https://doi.org/10.1016/j.annepidem.2008.08.099.Full Text Link to Item
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Epplein, Meira, Yurii B. Shvetsov, Lynne R. Wilkens, Adrian A. Franke, Robert V. Cooney, Loïc Le Marchand, Brian E. Henderson, Laurence N. Kolonel, and Marc T. Goodman. “Plasma carotenoids, retinol, and tocopherols and postmenopausal breast cancer risk in the Multiethnic Cohort Study: a nested case-control study.” Breast Cancer Res 11, no. 4 (2009): R49. https://doi.org/10.1186/bcr2338.Full Text Link to Item
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Epplein, Meira, Abraham M. Y. Nomura, Jean H. Hankin, Martin J. Blaser, Guillermo Perez-Perez, Grant N. Stemmermann, Lynne R. Wilkens, and Laurence N. Kolonel. “Association of Helicobacter pylori infection and diet on the risk of gastric cancer: a case-control study in Hawaii.” Cancer Causes Control 19, no. 8 (October 2008): 869–77. https://doi.org/10.1007/s10552-008-9149-2.Full Text Link to Item
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Epplein, Meira, Susan D. Reed, Lynda F. Voigt, Katherine M. Newton, Victoria L. Holt, and Noel S. Weiss. “Risk of complex and atypical endometrial hyperplasia in relation to anthropometric measures and reproductive history.” Am J Epidemiol 168, no. 6 (September 15, 2008): 563–70. https://doi.org/10.1093/aje/kwn168.Full Text Link to Item
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Epplein, M., S. D. Reed, L. F. Voigt, K. M. Newton, V. L. Holt, and N. S. Weiss. “Epplein et al. respond to "endometrial hyperplasia - Getting back to normal".” American Journal of Epidemiology 168, no. 6 (September 1, 2008): 575–76. https://doi.org/10.1093/aje/kwn167.Full Text
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Sun, Li-Min, Meira Epplein, Christopher I. Li, Thomas L. Vaughan, and Noel S. Weiss. “Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002.” Am J Epidemiol 162, no. 12 (December 15, 2005): 1174–78. https://doi.org/10.1093/aje/kwi345.Full Text Link to Item
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Epplein, Meira, Stephen M. Schwartz, John D. Potter, and Noel S. Weiss. “Smoking-adjusted lung cancer incidence among Asian-Americans (United States).” Cancer Causes Control 16, no. 9 (November 2005): 1085–90. https://doi.org/10.1007/s10552-005-0330-6.Full Text Link to Item
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Carr, Darcy B., Meira Epplein, Catherine O. Johnson, Thomas R. Easterling, and Cathy W. Critchlow. “A sister's risk: family history as a predictor of preeclampsia.” Am J Obstet Gynecol 193, no. 3 Pt 2 (September 2005): 965–72. https://doi.org/10.1016/j.ajog.2005.06.034.Full Text Link to Item
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Epplein, Meira, Ksenia P. Koon, Scott D. Ramsey, and John D. Potter. “Genetic services for familial cancer patients: a follow-up survey of National Cancer Institute Cancer Centers.” J Clin Oncol 23, no. 21 (July 20, 2005): 4713–18. https://doi.org/10.1200/JCO.2005.00.133.Full Text Link to Item
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Book Sections
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Varga, M. G., and M. Epplein. “Helicobacter Pylori-mediated carcinogenesis.” In Encyclopedia of Cancer, 187–97, 2018. https://doi.org/10.1016/B978-0-12-801238-3.65172-3.Full Text
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Conference Papers
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Brown, HannahSofia T., Meira Epplein, Helen Tang, and Katherine Garman. “Abstract PO-183: Racial disparities in Helicobacter pylori infection: A systematic review and retrospective study.” In Cancer Epidemiology, Biomarkers &Amp; Prevention, Vol. 31. American Association for Cancer Research (AACR), 2022. https://doi.org/10.1158/1538-7755.disp21-po-183.Full Text
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In, Haejin, Srawani Sarkar, Jessica Ward, Patricia Friedmann, Michael K. Parides, Julie Yang, and Meira Epplein. “SERUM PEPSINOGEN AS A BIOMARKER FOR GASTRIC CANCER IN THE UNITED STATES; A NESTED CASE-CONTROL STUDY USING THE PROSTATE, LUNG, COLORECTAL AND OVARIAN (PLCO) CANCER SCREENING TRIAL DATA.” In Gastroenterology, 162:S1319–S1319, 2022.Link to Item
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In, Haejin, Patricia Friedmann, Srawani Sarkar, Bruce Rapkin, Philip E. Castle, and Meira Epplein. “Risk factors for gastric cancers in the United States: Variation by anatomic site and race/ethnicity.” In Journal of Clinical Oncology, 39:189–189. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.3_suppl.189.Full Text
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In, H., P. Friedmann, M. Parides, S. Sarkar, P. E. Castle, and M. Epplein. “Serum Pepsinogen as a Biomarker for Gastric Cancer: A Nested Case-Control Study Using the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial Data.” In Annals of Surgical Oncology, 28:S41–S41, 2021.Link to Item
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In, H., P. Friedmann, S. Sarkar, B. Rapkin, P. E. Castle, and M. Epplein. “Risk Factors for Gastric Cancers in the US: Variation by Anatomic Site and Race/Ethnicity.” In Annals of Surgical Oncology, 28:S133–34, 2021.Link to Item
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Butt, J., W. J. Blot, K. Visvanathan, L. Le Marchand, Y. Chen, H. D. Sesso, S. Wassertheil-Smoller, et al. “Auto-antibodies to p53 and the Subsequent Development of Colorectal Cancer in a United States Prospective Cohort Consortium.” In Cancer Epidemiology, Biomarkers &Amp; Prevention, 29:690–690. American Association for Cancer Research (AACR), 2020. https://doi.org/10.1158/1055-9965.epi-20-0050.Full Text
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Reichstein, Jonathan, Alice Parish, Stephanie Garbarino, Julius Wilder, Meira Epplein, Deborah A. Fisher, Donna Niedzwiecki, Andrew J. Muir, and David A. Leiman. “Variations and Racial Disparities in Helicobacter pylori Guideline Adherence for Eradication Testing.” In American Journal of Gastroenterology, 115:S670–71, 2020.Link to Item
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Reichstein, Jonathan, Alice Parish, Stephanie Garbarino, Julius Wilder, Meira Epplein, Deborah A. Fisher, Donna Niedzwiecki, Andrew J. Muir, and David A. Leiman. “Antibiotic Resistance Rates in Helicobacter pylori Infection Derived from Retrospective Cure Rates.” In American Journal of Gastroenterology, 115:S670–S670, 2020.Link to Item
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Butt, Julia, Matthew G. Varga, Tianyi Wang, Shoichiro Tsugane, Taichi Shimazu, Wei Zheng, Christian C. Abnet, et al. “Smoking, Helicobacter Pylori Serology, and Gastric Cancer Risk in Prospective Studies from China, Japan, and Korea.” In Cancer Prev Res (Phila), 12:667–74, 2019. https://doi.org/10.1158/1940-6207.CAPR-19-0238.Full Text Link to Item
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Butt, J., W. J. Blot, M. J. Shrubsole, M. G. Varga, L. Hendrix, S. Crankshaw, T. Waterboer, M. Pawlita, and M. Epplein. “Performance of multiplex serology in discriminating active versus past Helicobacter pylori infection.” In Helicobacter, Vol. 24. WILEY, 2019.Link to Item
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Varga, M. G., J. Butt, W. J. Blot, L. Le Marchand, C. Haiman, Y. Chen, S. Wassertheil-Smoller, et al. “Racial differences in Helicobacter pylori antibody prevalence by year of birth and demographic factors in a consortium of US adults.” In Helicobacter, Vol. 24. WILEY, 2019.Link to Item
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Varga, Matthew G., Julia Butt, William Blot, Loic La Marchand, Chris Haiman, Yu Chen, Sylvia Wassertheil-Smoller, et al. “HELICOBACTER PYLORI ANTIBODY PREVALENCE BY YEAR OF BIRTH AND DEMOGRAPHIC FACTORS IN A CONSORTIUM OF US ADULTS.” In Gastroenterology, 156:S523–24. W B SAUNDERS CO-ELSEVIER INC, 2019.Link to Item
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Varga, Matthew G., Laura Hendrix, William Blot, Julia Butt, Howard D. Sesso, Richard M. Peek, John D. Potter, et al. “HELICOBACTER PYLORI INFECTION DOES NOT MODIFY THE PROTECTIVE EFFECT OF REGULAR ASPIRIN USE ON COLORECTAL CANCER RISK IN A POPULATION OF US ADULTS.” In Gastroenterology, 156:S821–22. W B SAUNDERS CO-ELSEVIER INC, 2019.Link to Item
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Butt, Julia, Matthew G. Varga, William J. Blot, Lauren Teras, Kala Visvanathan, Loïc Le Marchand, Christopher Haiman, et al. “Serologic Response to Helicobacter pylori Proteins Associated With Risk of Colorectal Cancer Among Diverse Populations in the United States.” In Gastroenterology, 156:175-186.e2, 2019. https://doi.org/10.1053/j.gastro.2018.09.054.Full Text Link to Item
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Wang, Tianyi, Hui Cai, Wei Zheng, Angelika Michel, Michael Pawlita, Ginger Milne, Yong-Bing Xiang, et al. “Abstract 2272: A prospective study of urinary prostaglandin E2 metabolite, Helicobacter pylori antibodies, and gastric cancer risk.” In Cancer Research, 77:2272–2272. American Association for Cancer Research (AACR), 2017. https://doi.org/10.1158/1538-7445.am2017-2272.Full Text
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Butt, Julia, Michael Pawlita, and Meira Epplein. “Abstract LB-361: Serology of Streptococcus gallolyticus subsp. gallolyticus and risk of colorectal cancer.” In Cancer Research, Vol. 76. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.am2016-lb-361.Full Text
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Wang, Tianyi, Hui Cai, Shizuka Sasazuki, Shoichiro Tsugane, Wei Zheng, Eo Rin Cho, Sun Ha Jee, et al. “Abstract 1735: Fruit and vegetable consumption and risk of gastric cancer: a prospective nested case-control study in China, Japan and Korea.” In Cancer Research, 76:1735–1735. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.am2016-1735.Full Text
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Epplein, Meira, Wei Zheng, Yong-Bing Xiang, Richard M. Peek, Honglan Li, Pelayo Correa, Jing Gao, et al. “Abstract 1027: Helicobacter pylori blood biomarkers for gastric cancer risk in the Shanghai Men's Health Study.” In Cancer Research, 72:1027–1027. American Association for Cancer Research (AACR), 2012. https://doi.org/10.1158/1538-7445.am2012-1027.Full Text
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Reed, Susan, Katherine Newton, Rochelle Garcia, Kimberly Allison, Lynda Voigt, Meira Epplein, Elizabeth Swisher, and Noel Weiss. “Complex hyperplasia with and without atypia - clinical outcomes and implications of progestin therapy in a 20 year cohort study of 1510 women.” In Cancer Research, Vol. 69. AMER ASSOC CANCER RESEARCH, 2009.Link to Item
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Carr, Darcy, Meira Epplein, Catherine Johnson, Thomas Easterling, and Cathy Critchlow. “A sister's risk: Family history as a predictor of hypertensive disorders of pregnancy.” In American Journal of Obstetrics and Gynecology, 191:S121–S121. Elsevier BV, 2004. https://doi.org/10.1016/j.ajog.2004.10.321.Full Text
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