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Michael Brown
Assistant Professor in Neurosurgery
Neurosurgery, Neuro-Oncology
michael.c.brown@duke.edu
Research
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At a Glance
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Credentials
Education
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Academic Experience
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Expertise
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Research
Selected Grants
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Publications
Selected Publications
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Teaching
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Advising & Mentoring
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Selected Grants
Epigenetic Programming of T Cells for Enhanced Cellular Immunotherapy
Research
Co Investigator ·
Awarded by National Cancer Institute ·
2024 - 2029
Role of ATRX deficiency as a determinant of topoisomerase 1 inhibitor sensitivity in high grade gliomas
Research
Co Investigator ·
Awarded by American Cancer Society, Inc. ·
2025 - 2028
Biomarkers to Advance Clinical Phenotypes of Low Back Pain (BACk)
Research
Co Investigator ·
Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases ·
2023 - 2028
Resolving Spatiotemporal Dynamics of Recombinant Poliovirus Immunotherapy
Research
Co Investigator ·
Awarded by National Cancer Institute ·
2023 - 2028
Social Health Factors Associated with the Transition from Acute to Chronic Low Back Pain
Fellowship
Collaborator ·
Awarded by National Institutes of Health ·
2024 - 2027
ATRXmutations,innate immune activation and therapeutic vunerabilityin malignant gliomas
Research
Investigator ·
Awarded by National Cancer Institute ·
2022 - 2027
Beyond tumor staging: measuring immune status at initial diagnosis to detect and prevent melanoma recurrence
Research
Investigator ·
Awarded by Department of Defense ·
2023 - 2026
Resolving targetable sex-differences in the immunobiology of gliomas and brain metastases.
Research
Principal Investigator ·
Awarded by Phi Beta Psi ·
2024 - 2025
Reviving cancer immune surveillance with CD4 T cell help
Research
Principal Investigator ·
Awarded by National Cancer Institute ·
2022 - 2025
Reviving cancer immune surveillance with CD4 T cell help
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2021 - 2023
Is Low Tumor Mutational Burden Predictive of Response to Oncolytic Polio Virus Therapy in Recurrent Glioblastoma?
Research
Collaborator ·
Awarded by National Institutes of Health ·
2019 - 2022
Cancer Immunotherapy Through Intratumoral Activation of Recall Responses
Fellowship
PI-Fellow ·
Awarded by National Institutes of Health ·
2018 - 2021
Cancer Immunotherapy Through Intratumoral Activation of Recall Responses
Fellowship
PI-Fellow ·
Awarded by National Cancer Center ·
2017 - 2019
Oncolytic Virotherapy of Meningeal Cancer
Research
Research Assistant ·
Awarded by National Institutes of Health ·
2009 - 2015