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Michael C. Fitzgerald
Professor of Chemistry
Chemistry
michael.c.fitzgerald@duke.edu
Box 90346, Durham, NC 27708-0346
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Research
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At a Glance
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Credentials
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Expertise
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Research
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Publications
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Teaching
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Advising & Mentoring
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Selected Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Institutes of Health ·
2025 - 2030
Chemical Biology Strategies to Resolve Plasmodium Heat Shock Protein Function
Research
Co Investigator ·
Awarded by National Institute of Allergy and Infectious Diseases ·
2023 - 2028
Noncovalent interaction of mutant KRAS inhibitors
Research
Co Investigator ·
Awarded by National Cancer Institute ·
2025 - 2027
Elucidating the Molecular Basis of Cellular Metal Stress by using Mass Spectrometry-Based Proteomic Methods
Research
Co-Principal Investigator ·
Awarded by National Institute of General Medical Sciences ·
2022 - 2026
MRI: Acquisition of a Microscale Thermophoresis System
Equipment
Major User ·
Awarded by National Science Foundation ·
2022 - 2025
Protein Stability Profiling for the Characterization of Alzheimer's Disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2022 - 2025
Global Measurements of Protein Folding Stability for Characterization of Aging and Disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2023
Discovery and Manipulation of Biomolecular-Noble Gas Interactions
Research
Co-Principal Investigator ·
Awarded by Defense Threat Reduction Agency ·
2018 - 2022
Anti-Malarial Drug Target Discovery using Energetics-Based Proteomics Methods
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2018 - 2020
GAANN - Department of Chemistry
Inst. Training Prgm or CME
Mentor ·
Awarded by Department of Education ·
2015 - 2019
Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer
Equipment
Major User ·
Awarded by National Institutes of Health ·
2018 - 2019
Analysis of Protein-Ligand Binding on the Proteomic Scale
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2019
MRI: Acquisition of a Triple Quadrupole LC/MS System
Equipment
Principal Investigator ·
Awarded by National Science Foundation ·
2015 - 2018
Acquisition of a MALDI-TOF Mass Spectrometer System at Duke University
Equipment
Principal Investigator ·
Awarded by North Carolina Biotechnology Center ·
2017 - 2018
Expanding the Scope of a Chemical Modification and Mass Spectrometry-Based Method for Protein-Ligand Binding Analysis
Research
Principal Investigator ·
Awarded by National Science Foundation ·
2013 - 2016
BC123577: Targeting Epigenetics Therapy for Estrogen Receptor Negative Breast Cancers
Research
Co Investigator ·
Awarded by United States Army Medical Research and Materiel Command ·
2013 - 2016
Structural Biology and Biophysics Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1994 - 2015
A Chemical Modification and Mass Spectrometry-Based Method for Analysis of Protein Folding and Ligand Binding
Research
Principal Investigator ·
Awarded by National Science Foundation ·
2009 - 2012
Analysis of PH1-Associated Alanine:Glyoxylate Aminotranferase (AGT) Using Yeast
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2008 - 2011
Purchase of a Q-TOF LC/MS System
Equipment
Principal Investigator ·
Awarded by National Institutes of Health ·
2010 - 2011
Identification of pharmacological chaperones for misfolded proteins
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2008 - 2011
Discovery of Cancer Imaging Probes using SUPREX
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2008 - 2010
Backbone-Backbone H-Bonds in Protein Folding
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2002 - 2008
Structure And Function Of Enzymes--Role Of Metals
Research
Collaborator ·
Awarded by National Institutes of Health ·
1977 - 2008
Backbone H-Bonds in Protein Folding (Supplement)
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2002 - 2007
Purchase of a High-Throughput MALDI TOF/TOF
Equipment
Principal Investigator ·
Awarded by National Institutes of Health ·
2006 - 2007
CAREER: Development of a New Mass Spectrometry-Based Approach fro Assaying Protein Stability and Initiation of a High Sc
Research
Principal Investigator ·
Awarded by National Science Foundation ·
2001 - 2006
Acquisition of a Time-Resolved Step-Scan Fourier Transform Infrared Spectrometer
Equipment
Co-Principal Investigator ·
Awarded by National Science Foundation ·
2001 - 2004
