Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow, Pediatric Cardiology, Pediatrics, Duke University 1994 - 1999
  • Chief Resident, Pediatrics, U Mass Memorial Medical Center 1993 - 1994
  • Chief Resident, Pediatrics, University of Maryland, Baltimore 1993 - 1994
  • Resident, Pediatrics, University of Maryland, Baltimore 1990 - 1993
  • M.D., Northeastern Ohio University 1990
• 

  Medical Licensure

  • 9401144. North Carolina. 1994
• 

  Duke Appointment History

  • Assistant Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 2006 - 2020
  • Assistant Clinical Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 2004 - 2006
  • Associate in the Department of Pediatrics, Pediatrics, Cardiology, Pediatrics 1999 - 2001
  • Instructor, Temporary in the Department of Pediatrics, Pediatrics, Cardiology, Pediatrics 1999
• 

  Leadership & Clinical Positions at Duke

  • Medical Director, Pediatric Heart Failure & Transplant Program
• Expertise
• 

  Subject Headings

  • Arrhythmias, Cardiac
  • Arrhythmogenic Right Ventricular Dysplasia
  • Cardiac Electrophysiology
  • Cardiac Pacing, Artificial
  • Cardiac Resynchronization Therapy
  • Cardiac Resynchronization Therapy Devices
  • Cardiomyopathies
  • Cardiomyopathy, Dilated
  • Cardiomyopathy, Hypertrophic
  • Cardiomyopathy, Restrictive
  • Channelopathies
  • Defibrillators, Implantable
  • Heart Conduction System
  • Heart Defects, Congenital
  • Heart Failure
  • Heart Transplantation
  • Pacemaker, Artificial
  • Ventricular Dysfunction
  • Ventricular Fibrillation
• Research
• 

  Selected Grants

  • "Multicenter, open-label, single dose study to evaluate safety, tolerability and pharmacokinetics of LCZ696 followed by a 52-week randomized, double-blind, parallel group, active-controlled study to evaluate the efficacy and safety of LCZ696 compared awarded by Novartis Pharma AG 2016 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Sparks, Joshua D., Ryan S. Cantor, Elizabeth Pruitt, James K. Kirklin, Michael Carboni, William Dreyer, Steven Kindel, Thomas D. Ryan, and W Robert Morrow. “New-onset diabetes after pediatric heart transplantation: A review of the Pediatric Heart Transplant Study.” Pediatr Transplant 23, no. 5 (August 2019): e13476. https://doi.org/10.1111/petr.13476.
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    • “Correction to: 2016 Scientific Sessions Abstract, Variability in Radiation Dose and Image Quality: A Comparison Across Fluoroscopy-system Vendors and Generations of Equipment.” Circulation 137, no. 17 (April 24, 2018). https://doi.org/10.1161/cir.0000000000000572.
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    • Kannankeril, Prince J., Jeremy P. Moore, Marina Cerrone, Silvia G. Priori, Naomi J. Kertesz, Pamela S. Ro, Anjan S. Batra, et al. “Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.” Jama Cardiol 2, no. 7 (July 1, 2017): 759–66. https://doi.org/10.1001/jamacardio.2017.1320.
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    • Mikati, Mohamad A., Yong-Hui Jiang, Michael Carboni, Vandana Shashi, Slave Petrovski, Rebecca Spillmann, Carol J. Milligan, et al. “Quinidine in the treatment of KCNT1-positive epilepsies.” Ann Neurol 78, no. 6 (December 2015): 995–99. https://doi.org/10.1002/ana.24520.
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    • Schumacher, Kurt R., Jeffrey Gossett, Kristine Guleserian, David C. Naftel, Elizabeth Pruitt, Debra Dodd, Michael Carboni, et al. “Fontan-associated protein-losing enteropathy and heart transplant: A Pediatric Heart Transplant Study analysis.” J Heart Lung Transplant 34, no. 9 (September 2015): 1169–76. https://doi.org/10.1016/j.healun.2015.03.022.
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    • Kindel, Steven J., Yuk M. Law, Clifford Chin, Michael Burch, James K. Kirklin, David C. Naftel, Elizabeth Pruitt, et al. “Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients.” J Am Coll Cardiol 66, no. 5 (August 4, 2015): 547–57. https://doi.org/10.1016/j.jacc.2015.05.063.
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    • Carboni, Michael P. “Sudden cardiac death after heart transplantation: can ICD prevent SCD?” Heart Rhythm 11, no. 10 (October 2014): 1691–92. https://doi.org/10.1016/j.hrthm.2014.08.039.
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    • Silva, Jennifer N. A., Christopher C. Erickson, Christopher D. Carter, E Anne Greene, Michal Kantoch, Kathryn K. Collins, Christina Y. Miyake, et al. “Management of pediatric tachyarrhythmias on mechanical support.” Circ Arrhythm Electrophysiol 7, no. 4 (August 2014): 658–63. https://doi.org/10.1161/CIRCEP.113.000973.
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    • McCanta, Anthony C., Melissa H. Kong, Michael P. Carboni, Ruth A. Greenfield, Patrick M. Hranitzky, and Ronald J. Kanter. “Laser lead extraction in congenital heart disease: a case-controlled study.” Pacing Clin Electrophysiol 36, no. 3 (March 2013): 372–80. https://doi.org/10.1111/pace.12071.
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    • Srinivasan, Chandra, Christoph P. Hornik, Angela Lloyd, Christine Meliones, Michael P. Carboni, William Darden, and Ronald J. Kanter. “Evaluation of Syncope and its Electrophysiologic Associations in Children and Adolescents: A Pediatric Referral Center Experience.” Circulation 126, no. 21 (November 20, 2012).
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    • Colan, Steven D., Girish Shirali, Renee Margossian, Dianne Gallagher, Karen Altmann, Charles Canter, Shan Chen, et al. “The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathy.” J Am Soc Echocardiogr 25, no. 8 (August 2012): 842-854.e6. https://doi.org/10.1016/j.echo.2012.05.004.
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    • Kanter, Ronald J., Ryan Pfeiffer, Dan Hu, Héctor Barajas-Martinez, Michael P. Carboni, and Charles Antzelevitch. “Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay.” Circulation 125, no. 1 (January 3, 2012): 14–22. https://doi.org/10.1161/CIRCULATIONAHA.111.054007.
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    • Gray, Amie, and Michael P. Carboni. “PROGRESSIVE RIGHT BUNDLE BRANCH BLOCK IN A CHILD WITH ACUTE CARDIAC ALLOGRAFT REJECTION.” Pediatric Transplantation 15 (August 1, 2011): 112–13.
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    • Hornik, Christoph P., Michael J. Campbell, Michael P. Carboni, Andrew J. Lodge, John F. Rhodes, and Ronald J. Kanter. “Preoperative diagnosis of long QT syndrome in an infant with tetralogy of Fallot.” Pediatr Cardiol 32, no. 6 (August 2011): 834–38. https://doi.org/10.1007/s00246-011-9957-0.
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    • Jeewa, Aamir, Clifford Chin, Elfriede Pahl, Andrew M. Atz, Michael P. Carboni, Margaret A. Tresler, David C. Naftel, Rose J. Rodriguez, Tina Allain-Rooney, and Anne I. Dipchand. “OUTCOMES AFTER CORONARY ARTERY REVASCULARIZATION PROCEDURES FOR ALLOGRAFT VASCULOPATHY IN PEDIATRIC HEART TRANSPLANT RECIPIENTS.” Pediatric Transplantation 15 (August 1, 2011): 53–53.
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    • Chemla, Jeremy C., Ronald J. Kanter, Michael P. Carboni, and Edward C. Smith. “Two children with "dropped head" syndrome due to lamin A/C mutations.” Muscle Nerve 42, no. 5 (November 2010): 839–41. https://doi.org/10.1002/mus.21820.
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    • Costanzo, Maria Rosa, Anne Dipchand, Randall Starling, Allen Anderson, Michael Chan, Shashank Desai, Savitri Fedson, et al. “The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients.” J Heart Lung Transplant 29, no. 8 (August 2010): 914–56. https://doi.org/10.1016/j.healun.2010.05.034.
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    • Ratnasamy, Christopher, Salim F. Idriss, Michael P. Carboni, and Ronald J. Kanter. “Arrhythmias in children having a single left superior vena cava and minimal structural heart disease.” J Cardiovasc Electrophysiol 20, no. 2 (February 2009): 182–86. https://doi.org/10.1111/j.1540-8167.2008.01307.x.
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    • Kanter, R. J., M. P. Carboni, and M. J. Silka. “Pediatric Arrhythmias,” December 1, 2006, 207–41. https://doi.org/10.1016/B978-032301281-2.50010-2.
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    • Cook, Amanda L., Priya S. Kishnani, Michael P. Carboni, Ronald J. Kanter, Y. T. Chen, Annette K. Ansong, Richard M. Kravitz, Henry Rice, and Jennifer S. Li. “Ambulatory electrocardiogram analysis in infants treated with recombinant human acid alpha-glucosidase enzyme replacement therapy for Pompe disease.” Genet Med 8, no. 5 (May 2006): 313–17. https://doi.org/10.1097/01.gim.0000217786.79173.a8.
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    • Nehgme, Rodrigo A., Michael P. Carboni, Jennifer Care, and John D. Murphy. “Transthoracic percutaneous access for electroanatomic mapping and catheter ablation of atrial tachycardia in patients with a lateral tunnel Fontan.” Heart Rhythm 3, no. 1 (January 2006): 37–43. https://doi.org/10.1016/j.hrthm.2005.09.027.
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    • Carboni, M., Z. -. S. Zhang, V. Neplioueva, C. F. Starmer, and A. O. Grant. “Slow sodium channel inactivation and use-dependent block modulated by the same domain IV S6 residue.” J Membr Biol 207, no. 2 (September 2005): 107–17. https://doi.org/10.1007/s00232-005-0805-0.
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    • Spencer, C. T., B. J. Byrne, M. H. Gewitz, S. B. Wechsler, A. C. Kao, E. P. Gerstenfeld, A. D. Merliss, M. P. Carboni, and R. M. Bryant. “Ventricular arrhythmia in the X-linked cardiomyopathy Barth syndrome.” Pediatr Cardiol 26, no. 5 (September 2005): 632–37. https://doi.org/10.1007/s00246-005-0873-z.
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    • Shah, Maully J., Rodrigo Nehgme, Michael Carboni, and John D. Murphy. “Endocardial atrial pacing lead implantation and midterm follow-up in young patients with sinus node dysfunction after the fontan procedure.” Pacing Clin Electrophysiol 27, no. 7 (July 2004): 949–54. https://doi.org/10.1111/j.1540-8159.2004.00564.x.
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    • Grant, Augustus O., Michael P. Carboni, Valentina Neplioueva, C Frank Starmer, Mirella Memmi, Carlo Napolitano, and Silvia Priori. “Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation.” J Clin Invest 110, no. 8 (October 2002): 1201–9. https://doi.org/10.1172/JCI15570.
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    • Grant, A. O., M. P. Carboni, V. Neplioueva, C. F. Starmer, M. Memmi, C. Napolitano, and S. Priori. “A spontaneous mutation identifies a residue critical for closed-state inactivation of cardiac sodium channels.” Circulation 104, no. 17 (October 23, 2001): 310–310.
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    • Grant, A. O., R. Chandra, C. Keller, M. Carboni, and C. F. Starmer. “Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells.” Biophys J 79, no. 6 (December 2000): 3019–35. https://doi.org/10.1016/S0006-3495(00)76538-6.
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    • Jacquette, B. A., M. P. Carboni, J. S. Li, and R. J. Kanter. “A comparison of transesophageal and intracardiac induction of atrial fibrillation in children: Implications in Wolff-Parkinson-White syndrome.” Journal of the American College of Cardiology 35, no. 2 (February 1, 2000): 516A-517A.
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    • Kanter, R. J., J. Papagiannis, M. P. Carboni, R. M. Ungerleider, W. E. Sanders, and J. M. Wharton. “Radiofrequency catheter ablation of supraventricular tachycardia substrates after mustard and senning operations for d-transposition of the great arteries.” J Am Coll Cardiol 35, no. 2 (February 2000): 428–41. https://doi.org/10.1016/s0735-1097(99)00557-4.
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    • Talner, N. S., and M. P. Carboni. “Chest pain in the adolescent and young adult.” Cardiol Rev 8, no. 1 (January 2000): 49–56. https://doi.org/10.1097/00045415-200008010-00009.
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    • Carboni, M. P., and R. E. Ringel. “Ductus arteriosus in premature infants beyond the second week of life.” Pediatr Cardiol 18, no. 5 (September 1997): 372–75. https://doi.org/10.1007/s002469900203.
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    • CARBONI, M. P., J. B. LONG, A. T. WINSLOW, and R. J. KANTER. “DURATION OF TREATMENT NECESSARY TO PREVENT SYMPTOM RECURRENCE IN YOUNG-PATIENTS WITH NEUROCARDIOGENIC SYNCOPE.” Circulation 92, no. 8 (October 15, 1995): 3677–3677.
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    • CARBONI, M. P., and R. E. RINGEL. “PATENT DUCTUS-ARTERIOSUS IN PREMATURE-INFANTS GREATER-THAN 2 WEEKS OF AGE - UTILITY OF ECHOCARDIOGRAPHIC EXAMINATION.” Pediatric Research 35, no. 4 (April 1, 1994): A218–A218.
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  • Conference Papers

    • Hill, Kevin D., Steve D. Mann, Michael P. Carboni, Thomas P. Doyle, Salim F. Idriss, Dana F. Janssen, George T. Nicholson, Shyam Sathanandam, and Greg A. Fleming. “Variability in radiation dose and image quality: A comparison across fluoroscopy-system vendors, generations of equipment and institutions.” In Catheter Cardiovasc Interv, 92:E471–77, 2018. https://doi.org/10.1002/ccd.27793.
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    • Godown, J., E. Pruitt, J. Vo, D. A. Dodd, I. Lytrivi, G. J. Boyle, D. Sutcliffe, et al. “Practice Variation in the Diagnosis of Acute Rejection Among Pediatric Heart Transplant Centers: An Analysis of the Pediatric Heart Transplant Study (PHTS) Database.” In Journal of Heart and Lung Transplantation, 37:S191–S191. ELSEVIER SCIENCE INC, 2018.
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    • Hill, Kevin D., Michael P. Carboni, Thomas P. Doyle, Salim Idriss, Dana Janssen, George Nicholson, Shyam Sathanandam, Steve Mann, and Gregory Fleming. “Variability in Radiation Dose and Image Quality: A Comparison Across Fluoroscopy-system Vendors and Generations of Equipment.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Kannankeril, Prince J., Jeremy P. Moore, Marina Cerrone, Silvia G. Priori, Naomi J. Kertesz, Pam Ro, Anjan S. Batra, et al. “A Prospective Randomized Placebo-Controlled Crossover Trial of Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Jeewa, Aamir, Clifford Chin, Elfriede Pahl, Andrew M. Atz, Michael P. Carboni, Elizabeth Pruitt, David C. Naftel, Rose Rodriguez, Anne I. Dipchand, and Anne I. Pediatric Heart Transplant Study (PHTS) Investigators. “Outcomes after percutaneous coronary artery revascularization procedures for cardiac allograft vasculopathy in pediatric heart transplant recipients: A multi-institutional study.” In J Heart Lung Transplant, 34:1163–68, 2015. https://doi.org/10.1016/j.healun.2014.11.011.
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    • Chen, Dong-Feng, Robert D. B. Jaquiss, Andrew J. Lodge, and Michael P. Carboni. “82-P.” In Human Immunology, 73:104–104. Elsevier BV, 2012. https://doi.org/10.1016/j.humimm.2012.07.208.
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    • Chen, Dong-Feng, Wendy Wegner, Linda Peel, and Michael P. Carboni. “7-OR.” In Human Immunology, 73:7–8. Elsevier BV, 2012. https://doi.org/10.1016/j.humimm.2012.07.019.
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    • Kindel, S. J., C. Chin, Y. Law, M. M. Burch, J. K. Kirklin, D. C. Naftel, M. P. Carboni, et al. “133 Cardiac Allograft Vasculopathy (CAV) in Children: An 18 Year Pediatric Heart Transplant Study (PHTS) Analysis in 3120 Patients.” In The Journal of Heart and Lung Transplantation, 31:S53–54. Elsevier BV, 2012. https://doi.org/10.1016/j.healun.2012.01.137.
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    • Carothers, B., M. Carboni, J. F. Rhodes, M. J. Campbell, J. W. Delaney, A. S. Green, and P. Barker. “Myocardial Strain by Velocity Vector Imaging as a Marker for Function and Rejection in Pediatric Heart Transplant Recipients,” n.d.

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