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Michael Barry Kastan

William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
DUMC Box 3917, 10 Bryan Searle Drive, Rm 422, Durham, NC 27710
DUMC Box 3917, 10 Bryan Searle Drive, Rm 422, Durham, NC 27710

Overview


Dr. Kastan earned his M.D./Ph.D. from Washington University School of Medicine and did his clinical training in Pediatrics and Pediatric Hematology-Oncology at Johns Hopkins. He was a Professor of Oncology at Johns Hopkins prior to becoming Chair of the Hematology-Oncology Department and later Cancer Center Director at St. Jude Children’s Research Hospital, before moving to Duke in 2011, where he currently serves as the Executive Director of the Duke Cancer Institute and is the William and Jane Shingleton Professor of Pharmacology and Cancer Biology. His laboratory research has focused on cellular responses to DNA damage, including many highly cited publications reporting the roles of p53 and ATM in DNA damage signaling. Among his numerous honors are election to the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences, and receipt of the AACR-G.H.A. Clowes Memorial Award and Failla Award from the Radiation Research Society. He has served as Chair of the Board of Scientific Counselors of the National Cancer Institute (NCI), on the Boards of Directors of the American Association for Cancer Research (AACR) and the American Association of Cancer Institutes (AACI), and as Editor-in-Chief of the journal Molecular Cancer Research. His lab continues to study molecular and biochemical controls of cellular stress responses, particularly those related to DNA damage, and has spun out two companies focused on novel anti-cancer therapeutics.

Current Appointments & Affiliations


William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology · 2012 - Present Pharmacology & Cancer Biology, Basic Science Departments
Professor of Pharmacology and Cancer Biology · 2012 - Present Pharmacology & Cancer Biology, Basic Science Departments
Director of the Duke Cancer Institute · 2011 - Present Duke Cancer Institute, Institutes and Centers
Professor of Pediatrics · 2012 - Present Pediatrics, Clinical Science Departments
Member of the Duke Cancer Institute · 2010 - Present Duke Cancer Institute, Institutes and Centers

Education, Training & Certifications


Washington University in St. Louis · 1984 M.D.
Washington University in St. Louis · 1984 Ph.D.