Michael J Pencina
Professor of Biostatistics & Bioinformatics
As Vice Dean for Data Science, Dr. Pencina is responsible for developing and implementing quantitative science strategies as they pertain to the education and training, and laboratory, clinical science, and data science missions of the School of Medicine. Dr. Pencina is a Professor of Biostatistics and Bioinformatics at Duke University and Director of Duke AI Health. Previously, he served as Director of Biostatistics at the Duke Clinical Research Institute.
Dr. Pencina is an internationally recognized authority in risk prediction model development and evaluation. Expert panels and guideline groups frequently recommend methods proposed in his research and have adopted them as the most promising new statistical tools in assessing and quantifying model performance.
Dr. Pencina is actively involved in the design, conduct and analysis of clinical studies with particular focus on novel and efficient designs and applications of machine learning for medical decision support. He interacts regularly with investigators from academic and industry institutions as well as the Food and Drug Administration.
Thomson Reuters/Clarivate Analytics recognized Dr. Pencina as a Highly Cited Researcher in two fields, social sciences and clinical medicine, for the years 2014 – 2020. He is co-author of more than 370 manuscripts published in peer-reviewed journals and has been cited over 90,000 times in professional publications. He serves as Deputy Editor for Statistics at JAMA-Cardiology and Associate Editor for Statistics in Medicine.
In 2003, Dr. Pencina received his PhD in Mathematics and Statistics from Boston University. He holds master’s degrees from the University of Warsaw in actuarial mathematics and business culture. He joined the Duke University faculty in 2013. Dr. Pencina served as an Associate Professor in the Department of Biostatistics at Boston University and the Framingham Heart Study and as Director of Statistical Consulting at the Harvard Clinical Research Institute.
strategies as they pertain to the education and training, and laboratory, clinical science, and data science missions of the School of Medicine. Dr. Pencina is a Professor of Biostatistics and Bioinformatics at Duke University and Director of Duke AI Health. Previously, he served as Director of Biostatistics at the Duke Clinical Research Institute.
Dr. Pencina is an internationally recognized authority in risk prediction model development and evaluation. Expert panels and guideline groups frequently recommend methods proposed in his research and have adopted them as the most promising new statistical tools in assessing and quantifying model performance.
Dr. Pencina is actively involved in the design, conduct and analysis of clinical studies with particular focus on novel and efficient designs and applications of machine learning for medical decision support. He interacts regularly with investigators from academic and industry institutions as well as the Food and Drug Administration.
Thomson Reuters/Clarivate Analytics recognized Dr. Pencina as a Highly Cited Researcher in two fields, social sciences and clinical medicine, for the years 2014 – 2020. He is co-author of more than 370 manuscripts published in peer-reviewed journals and has been cited over 83,000 times in professional publications. He serves as Deputy Editor for Statistics at JAMA-Cardiology and Associate Editor for Statistics in Medicine.
In 2003, Dr. Pencina received his PhD in Mathematics and Statistics from Boston University. He holds master’s degrees from the University of Warsaw in actuarial mathematics and business culture. He joined the Duke University faculty in 2013. Dr. Pencina served as an Associate Professor in the Department of Biostatistics at Boston University and the Framingham Heart Study and as Director of Statistical Consulting at the Harvard Clinical Research Institute.
Current Research Interests
- Development and assessment of performance of risk prediction models
- Use of electronic health records (EHR) for predictive medicine
- Assessment of the usefulness of new biomarkers
- Optimal treatment guidelines and resource utilization
- Risk communication strategies: novel approaches
- Design of clinical trials with composite outcomes
- Data monitoring committees (DMC): role, mandate and operation
Current Appointments & Affiliations
- Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2021
- Vice Dean, Data Science and Information Technology, School of Medicine, Duke University 2018
- Director of Duke AI Health, School of Medicine, Duke University 2021
- Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2013
Contact Information
- 200 Trent Drive, M144 Davison Bldg, Durham, NC 27705
- Duke Box 2927, Durham, NC 27710
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(919) 613-9066
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Duke SoM Data Science & Information Technology
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Duke University School of Medicine, Leadership Profile
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Google Scholar Profile for Dr. Michael Pencina
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Independent Monitoring Committees, Clinical Trials Transformation Initiative (CITI)
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Scientific Council of the Medical Research Agency of the Republic of Poland
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The Framingham Heart Study
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YouTube Channel for Dr. Michael Pencina
- Background
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Education, Training, & Certifications
- Ph.D., Boston University 2003
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Previous Appointments & Affiliations
- Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2013 - 2020
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Leadership & Clinical Positions at Duke
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Vice Dean for Data Science & Information Technology
, Duke University School of Medicine, 06/2018 – Present
Professor of Biostatistics & Bioinformatics , Department of Biostatistics & Bioinformatics, Duke University School of Medicine, 06/2013 – Present
Director of DCRI Biostatistics , Duke Clinical Research Institute (DCRI), Duke University, 06/2013 – 06/2018
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Vice Dean for Data Science & Information Technology
, Duke University School of Medicine, 06/2018 – Present
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Academic Positions Outside Duke
- Director of Statistical Consulting, Harvard Clinical Research Institute, Harvard Medical School. 2010 - 2013
- Associate Professor, Department of Biostatistics, School of Public Health, Boston University. 2008 - 2013
- Senior Consulting Statistician, Harvard Clinical Research Institute, Harvard Medical School. 2008 - 2010
- Consulting Statistician, Harvard Clinical Research Institute, Harvard Medical School. 2007
- Research Assistant Professor, Department of Mathematics & Statistics, Boston University. 2003 - 2008
- Research Assistant & Teaching Assistant, Department of Mathematics & Statistics, Boston University. 1999 - 2003
- Recognition
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In the News
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JAN 27, 2023 Duke Health News -
JAN 23, 2023 Duke AI Health -
JUL 26, 2022 Duke Health News -
JUL 22, 2020 School of Medicine -
NOV 19, 2019 -
DEC 11, 2018 Duke Health News -
NOV 27, 2018 -
APR 19, 2017 Duke Health News -
NOV 13, 2016 Duke Health News -
JAN 27, 2015 TIME -
JAN 27, 2015 TIME -
JAN 27, 2015 The New York Times -
JAN 27, 2015 The New York Times -
JUN 24, 2014 Duke Today -
JUN 24, 2014 -
MAR 20, 2014 USA Today -
MAR 20, 2014
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Awards & Honors
- Highly Cited Researcher. Thomson Reuters. 2020
- Charter Member. Scientific Council of the Medical Research Agency of the Republic of Poland. 2019
- Highly Cited Researcher. Thomson Reuters. 2018
- Highly Cited Researcher. Thomson Reuters. 2017
- Highly Cited Researcher. Thomson Reuters. 2016
- Keynote Speaker, Remington Methodology Lecture. American Heart Association Council on Epidemiology and Prevention. 2016
- Highly Cited Researcher. Thomson Reuters. 2015
- Highly Cited Researcher. Thomson Reuters. 2014
- Expertise
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Subject Headings
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Global Scholarship
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Expertise
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- Research
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Selected Grants
- Improving Racial Equity in Clinical Decision Making about Access to Organ Transplant awarded by National Institutes of Health 2022 - 2027
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2022 - 2027
- Improving stroke risk prediction with cohort data and machine learning methods awarded by National Institute of Neurological Disorders and Stroke 2020 - 2025
- New causal inference methods for cluster randomized trials with post-randomization selection awarded by Patient Centered Outcomes Research Institute 2020 - 2024
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2013 - 2024
- Cardiovascular Risk Prediction for Improved Maternal Health awarded by Foundation for Anesthesia Education and Research 2022 - 2023
- Advanced computational approaches for integrating data to assess effect heterogeneity awarded by Johns Hopkins University 2021 - 2023
- The HPV, HIV and Oral Microbiome Interplay in Children and Adolescents in Nigeria (HOMINI) Project awarded by Rutgers, The State University of New Jersey 2022 - 2023
- Addressing Bias from Missing Data in EHR Based Studies of CVD awarded by National Institutes of Health 2018 - 2023
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2023
- Health AI Coalition Workgroup awarded by Mitre Corporation 2022
- Methods for the Design and Conduct of Subgroup Analysis in Observational Studies awarded by Patient Centered Outcomes Research Institute 2019 - 2022
- Administrative Claims-based Efficiencies for the Advancement of Regulatory Sciences awarded by Burroughs Wellcome Fund 2014 - 2021
- QuBBD: Deep Poisson Methods for Biomedical Time-to-Event and Longitudinal Data awarded by National Institutes of Health 2017 - 2021
- Risk Prediction for Secondary Events in Adults with Arteriosclerotic Cardiovascular Disease (ASCVD) awarded by Regeneron Pharmaceuticals, Inc. 2015 - 2021
- Preventing Cardiovascular Disease through Improved Risk Prediction and Communication awarded by National Institutes of Health 2016 - 2020
- Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) awarded by Patient Centered Outcomes Research Institute 2015 - 2020
- Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research awarded by Patient Centered Outcomes Research Institute 2013 - 2020
- Cardiovascular Risk Profile of LAL Deficiency Patients awarded by Alexion Pharmaceuticals, Inc. 2016 - 2020
- Financial and Social Behavioral Economic Incentives to Increase Physical Activity in Adolescents and Young Adults for Cardiovascular Health awarded by National Institutes of Health 2018 - 2019
- Predictive Analytic Treatment effect Heterogeneity (PATH) awarded by Tufts Medical Center 2018 - 2019
- Risk prediction for S Arteriosclerotic Cardiovascular Disease (ASCVD) in persons on statins awarded by Regeneron Pharmaceuticals, Inc. 2016 - 2019
- Semi-automated terminology extension and term extraction enhancement to improve disease stratification using clinical notes awarded by National Institutes of Health 2017 - 2019
- Duke CTSA (UL1): Statistical methods for complex data in CV disease research awarded by National Institutes of Health 2013 - 2018
- Modified KOR Phase 2A Study awarded by National Institutes of Health 2014 - 2017
- CKD Biomarkers Consortium awarded by University of Pennsylvania 2015 - 2017
- Assessment of the Number of Patients Treated for In-stent Restenosis using the Duke Health System awarded by Abbott Cardiovascular Systems, Inc. 2016 - 2017
- HIV and Asthma in the Post- ART Era awarded by National Institutes of Health 2014 - 2016
- FAST- MAS Administrative Task Year 3 awarded by National Institutes of Health 2014 - 2015
- Southern Consortium Node of the Clinical Trials Network awarded by Medical University of South Carolina 2013 - 2015
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External Relationships
- American Medical Association
- InQuera
- Instytut Kardiologii, Warsaw, Poland
- Janssen Pharmaceuticals (Johnson & Johnson)
- McGill University Health System/Doggone Foundation
- Novavax, Inc.
- Polska Agencja Badan Medycznych/Polish Medical Research Agency
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Bedoya, Armando D., Nicoleta J. Economou-Zavlanos, Benjamin A. Goldstein, Allison Young, J Eric Jelovsek, Cara O’Brien, Amanda B. Parrish, et al. “A framework for the oversight and local deployment of safe and high-quality prediction models.” J Am Med Inform Assoc 29, no. 9 (August 16, 2022): 1631–36. https://doi.org/10.1093/jamia/ocac078.Full Text Link to Item
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Khan, Sadiya S., Courtney Page, Daniel M. Wojdyla, Yosef Y. Schwartz, Philip Greenland, and Michael J. Pencina. “Predictive Utility of a Validated Polygenic Risk Score for Long-Term Risk of Coronary Heart Disease in Young and Middle-Aged Adults.” Circulation 146, no. 8 (August 2022): 587–96. https://doi.org/10.1161/circulationaha.121.058426.Full Text
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Navar, Ann Marie, Gregg C. Fonarow, and Michael J. Pencina. “Time to Revisit Using 10-Year Risk to Guide Statin Therapy.” Jama Cardiol 7, no. 8 (August 1, 2022): 785–86. https://doi.org/10.1001/jamacardio.2022.1883.Full Text Link to Item
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Pencina, Karol M., Michael J. Pencina, Line Dufresne, Michael Holmes, George Thanassoulis, and Allan D. Sniderman. “An adverse lipoprotein phenotype-hypertriglyceridaemic hyperapolipoprotein B-and the long-term risk of type 2 diabetes: a prospective, longitudinal, observational cohort study.” Lancet Healthy Longev 3, no. 5 (May 2022): e339–46. https://doi.org/10.1016/S2666-7568(22)00079-4.Full Text Link to Item
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Yan, Mengying, Michael J. Pencina, L Ebony Boulware, and Benjamin A. Goldstein. “Observability and its impact on differential bias for clinical prediction models.” J Am Med Inform Assoc 29, no. 5 (April 13, 2022): 937–43. https://doi.org/10.1093/jamia/ocac019.Full Text Link to Item
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Cerrato, Paul, John Halamka, and Michael Pencina. “A proposal for developing a platform that evaluates algorithmic equity and accuracy.” Bmj Health Care Inform 29, no. 1 (April 2022). https://doi.org/10.1136/bmjhci-2021-100423.Full Text Link to Item
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Irzmański, Robert, Renata Glowczynska, Maciej Banach, Dominika Szalewska, Ryszard Piotrowicz, Ilona Kowalik, Michael J. Pencina, et al. “Prognostic Impact of Hybrid Comprehensive Telerehabilitation Regarding Diastolic Dysfunction in Patients with Heart Failure with Reduced Ejection Fraction-Subanalysis of the TELEREH-HF Randomized Clinical Trial.” J Clin Med 11, no. 7 (March 26, 2022). https://doi.org/10.3390/jcm11071844.Full Text Link to Item
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Piotrowicz, E., M. Pencina, G. Opolski, W. Zaręba, M. Banach, I. Kowalik, P. Orzechowski, et al. “Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial.” Applied Sciences (Switzerland) 12, no. 5 (March 1, 2022). https://doi.org/10.3390/app12052595.Full Text
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Stone, Neil J., Sidney C. Smith, Carl E. Orringer, Nancy A. Rigotti, Ann Marie Navar, Sadiya S. Khan, Daniel W. Jones, et al. “Managing Atherosclerotic Cardiovascular Risk in Young Adults: JACC State-of-the-Art Review.” J Am Coll Cardiol 79, no. 8 (March 1, 2022): 819–36. https://doi.org/10.1016/j.jacc.2021.12.016.Full Text Link to Item
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Orzechowski, Piotr, Ryszard Piotrowicz, Wojciech Zareba, Michael J. Pencina, Ilona Kowalik, Ewa Komar, Grzegorz Opolski, et al. “Antiarrhythmic effect of 9-week hybrid comprehensive telerehabilitation and its influence on cardiovascular mortality in long-term follow-up - subanalysis of the TELEREHabilitation in Heart Failure Patients randomized clinical trial.” Arch Med Sci 18, no. 2 (2022): 293–306. https://doi.org/10.5114/aoms/136563.Full Text Link to Item
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Piotrowicz, Ewa, Piotr Orzechowski, Ilona Kowalik, Wojciech Zaręba, Michael Pencina, Ewa Komar, Grzegorz Opolski, et al. “Predictors of proarrhythmic effect in heart failure patients after 9-week hybrid comprehensive telerehabilitation and their influence on cardiovascular mortality in long-term follow-up: Subanalysis of the TELEREH-HF randomized clinical trial.” J Electrocardiol 75 (2022): 28–35. https://doi.org/10.1016/j.jelectrocard.2022.10.004.Full Text Link to Item
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Orzechowski, Piotr, Ryszard Piotrowicz, Wojciech Zaręba, Renata Główczyńska, Dominika Szalewska, Sławomir Pluta, Robert Irzmański, et al. “Assessment of ECG during hybrid comprehensive telerehabilitation in heart failure patients-Subanalysis of the Telerehabilitation in Heart Failure Patients (TELEREH-HF) randomized clinical trial.” Annals of Noninvasive Electrocardiology : The Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 26, no. 6 (November 2021): e12887. https://doi.org/10.1111/anec.12887.Full Text
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Thomas, Laine Elliott, Ann Marie Navar, and Michael J. Pencina. “Extrapolating Survival From Randomized Clinical Trial Data-Possibilities and Caution.” Jama Cardiol 6, no. 11 (November 1, 2021): 1305–7. https://doi.org/10.1001/jamacardio.2021.2629.Full Text Link to Item
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Thomas, Laine Elliott, Mintu P. Turakhia, and Michael J. Pencina. “Competing Risks, Treatment Switching, and Informative Censoring.” Jama Cardiol 6, no. 8 (August 1, 2021): 871–73. https://doi.org/10.1001/jamacardio.2021.1239.Full Text Link to Item
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Singh, Vikash, Michael Pencina, Andrew J. Einstein, Joanna X. Liang, Daniel S. Berman, and Piotr Slomka. “Impact of train/test sample regimen on performance estimate stability of machine learning in cardiovascular imaging.” Sci Rep 11, no. 1 (July 14, 2021): 14490. https://doi.org/10.1038/s41598-021-93651-5.Full Text Link to Item
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Engelhard, Matthew M., Ann Marie Navar, and Michael J. Pencina. “Incremental Benefits of Machine Learning-When Do We Need a Better Mousetrap?” Jama Cardiol 6, no. 6 (June 1, 2021): 621–23. https://doi.org/10.1001/jamacardio.2021.0139.Full Text Link to Item
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Główczyńska, Renata, Ewa Piotrowicz, Dominika Szalewska, Ryszard Piotrowicz, Ilona Kowalik, Michael J. Pencina, Wojciech Zaręba, et al. “Effects of hybrid comprehensive telerehabilitation on cardiopulmonary capacity in heart failure patients depending on diabetes mellitus: subanalysis of the TELEREH-HF randomized clinical trial.” Cardiovascular Diabetology 20, no. 1 (May 2021): 106. https://doi.org/10.1186/s12933-021-01292-9.Full Text
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Jones, W Schuyler, Hillary Mulder, Lisa M. Wruck, Michael J. Pencina, Sunil Kripalani, Daniel Muñoz, David L. Crenshaw, et al. “Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease.” The New England Journal of Medicine 384, no. 21 (May 2021): 1981–90. https://doi.org/10.1056/nejmoa2102137.Full Text
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Szalewska, Dominika, Renata Główczyńska, Ryszard Piotrowicz, Ilona Kowalik, Michael J. Pencina, Grzegorz Opolski, Wojciech Zaręba, et al. “An aetiology-based subanalysis of the Telerehabilitation in Heart Failure Patients (TELEREH-HF) trial.” Esc Heart Fail 8, no. 2 (April 2021): 1263–73. https://doi.org/10.1002/ehf2.13189.Full Text Link to Item
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Wosik, Jedrek, Megan E. B. Clowse, Robert Overton, Bhargav Adagarla, Nicoleta Economou-Zavlanos, Joanna Cavalier, Ricardo Henao, et al. “Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care.” Am Heart J 231 (January 2021): 1–5. https://doi.org/10.1016/j.ahj.2020.10.074.Full Text Link to Item
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Allan, Sniderman, Michael Pencina, and George Thanassoulis. “Clinical reasoning and prevention of cardiovascular disease.” J Clin Lipidol 15, no. 3 (2021): 394–98. https://doi.org/10.1016/j.jacl.2021.04.001.Full Text Link to Item
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Sriram, Karishma, Hillary S. Mulder, Heather R. Frank, Taruni S. Santanam, Asheley C. Skinner, Eliana M. Perrin, Sarah C. Armstrong, Eric D. Peterson, Michael J. Pencina, and Charlene A. Wong. “The Dose-Response Relationship Between Physical Activity and Cardiometabolic Health in Adolescents.” Am J Prev Med 60, no. 1 (January 2021): 95–103. https://doi.org/10.1016/j.amepre.2020.06.027.Full Text Link to Item
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Pluta, Sławomir, Ewa Piotrowicz, Ryszard Piotrowicz, Ewa Lewicka, Wojciech Zaręba, Monika Kozieł, Ilona Kowalik, et al. “Remote Monitoring of Cardiac Implantable Electronic Devices in Patients Undergoing Hybrid Comprehensive Telerehabilitation in Comparison to the Usual Care. Subanalysis from Telerehabilitation in Heart Failure Patients (TELEREH-HF) Randomised Clinical Trial.” J Clin Med 9, no. 11 (November 20, 2020). https://doi.org/10.3390/jcm9113729.Full Text Link to Item
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Goldstein, Benjamin A., and Michael J. Pencina. “Testing Clinical Prediction Models.” Jama 324, no. 19 (November 17, 2020): 1998–99. https://doi.org/10.1001/jama.2020.19392.Full Text Link to Item
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Chapfuwa, Paidamoyo, Chenyang Tao, Chunyuan Li, Irfan Khan, Karen J. Chandross, Michael J. Pencina, Lawrence Carin, and Ricardo Henao. “Calibration and Uncertainty in Neural Time-to-Event Modeling.” Ieee Trans Neural Netw Learn Syst PP (October 29, 2020). https://doi.org/10.1109/TNNLS.2020.3029631.Full Text Link to Item
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Thomas, Laine E., Robert O. Bonow, and Michael J. Pencina. “Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19).” Jama Cardiol 5, no. 9 (September 1, 2020): 988–90. https://doi.org/10.1001/jamacardio.2020.1874.Full Text Link to Item
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Pencina, Michael J., Karol M. Pencina, Donald Lloyd-Jones, Alberico L. Catapano, George Thanassoulis, and Allan D. Sniderman. “The Expected 30-Year Benefits of Early Versus Delayed Primary Prevention of Cardiovascular Disease by Lipid Lowering.” Circulation 142, no. 9 (September 2020): 827–37. https://doi.org/10.1161/CIRCULATIONAHA.120.045851.Full Text Link to Item
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Sniderman, Allan D., George Thanassoulis, and Michael Pencina. “Prevention of cardiovascular disease: time for a course correction.” Eur Heart J 41, no. 31 (August 14, 2020): 3016–17. https://doi.org/10.1093/eurheartj/ehaa259.Full Text Link to Item
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Curfman, Gregory, Deepak L. Bhatt, and Michael Pencina. “Federal judge invalidates icosapent ethyl patents - but on the basis of a common statistical mistake.” Nat Biotechnol 38, no. 8 (August 2020): 939–41. https://doi.org/10.1038/s41587-020-0616-y.Full Text Link to Item
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Frank, Heather R., Hillary Mulder, Karishma Sriram, Taruni S. Santanam, Asheley C. Skinner, Eliana M. Perrin, Sarah C. Armstrong, Eric D. Peterson, Michael Pencina, and Charlene A. Wong. “The Dose-Response Relationship Between Physical Activity and Cardiometabolic Health in Young Adults.” J Adolesc Health 67, no. 2 (August 2020): 201–8. https://doi.org/10.1016/j.jadohealth.2020.04.021.Full Text Link to Item
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Thomas, Laine E., Fan Li, and Michael J. Pencina. “Overlap Weighting: A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial.” Jama 323, no. 23 (June 2020): 2417–18. https://doi.org/10.1001/jama.2020.7819.Full Text
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Thomas, Laine E., Robert O. Bonow, and Michael J. Pencina. “Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19).” Jama Cardiol, May 5, 2020. https://doi.org/10.1001/jamacardio.2020.1874.Full Text Link to Item
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Cardet, Juan Carlos, Paula J. Busse, Jennifer K. Carroll, Thomas B. Casale, Tamera Coyne-Beasley, Sherrie Dixon-Williams, Maureen Fagan, et al. “Adherence to adding inhaled corticosteroids to rescue therapy in a pragmatic trial with adults with asthma: A pilot study.” Ann Allergy Asthma Immunol 124, no. 5 (May 2020): 487-493.e1. https://doi.org/10.1016/j.anai.2019.12.027.Full Text Link to Item
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Marquis-Gravel, Guillaume, Matthew T. Roe, Holly R. Robertson, Robert A. Harrington, Michael J. Pencina, Lisa G. Berdan, Bradley G. Hammill, et al. “Rationale and Design of the Aspirin Dosing-A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) Trial.” Jama Cardiol 5, no. 5 (May 1, 2020): 598–607. https://doi.org/10.1001/jamacardio.2020.0116.Full Text Link to Item
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Pencina, Michael J., Benjamin A. Goldstein, and Ralph B. D’Agostino. “Prediction Models - Development, Evaluation, and Clinical Application.” N Engl J Med 382, no. 17 (April 23, 2020): 1583–86. https://doi.org/10.1056/NEJMp2000589.Full Text Link to Item
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Piotrowicz, Ewa, Michael J. Pencina, Grzegorz Opolski, Wojciech Zareba, Maciej Banach, Ilona Kowalik, Piotr Orzechowski, et al. “Effects of a 9-Week Hybrid Comprehensive Telerehabilitation Program on Long-term Outcomes in Patients With Heart Failure: The Telerehabilitation in Heart Failure Patients (TELEREH-HF) Randomized Clinical Trial.” Jama Cardiol 5, no. 3 (March 1, 2020): 300–308. https://doi.org/10.1001/jamacardio.2019.5006.Full Text Link to Item
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Thomas, Laine, Fan Li, and Michael Pencina. “Using Propensity Score Methods to Create Target Populations in Observational Clinical Research.” Jama 323, no. 5 (February 4, 2020): 466–67. https://doi.org/10.1001/jama.2019.21558.Full Text Link to Item
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Kent, David M., David van Klaveren, Jessica K. Paulus, Ralph D’Agostino, Steve Goodman, Rodney Hayward, John P. A. Ioannidis, et al. “The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement: Explanation and Elaboration.” Ann Intern Med 172, no. 1 (January 7, 2020): W1–25. https://doi.org/10.7326/M18-3668.Full Text Link to Item
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Kent, David M., Jessica K. Paulus, David van Klaveren, Ralph D’Agostino, Steve Goodman, Rodney Hayward, John P. A. Ioannidis, et al. “The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement.” Ann Intern Med 172, no. 1 (January 7, 2020): 35–45. https://doi.org/10.7326/M18-3667.Full Text Link to Item
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Chapfuwa, Paidamoyo, Serge Assaad, Shuxi Zeng, Michael J. Pencina, Lawrence Carin, and Ricardo Henao. “Survival Analysis meets Counterfactual Inference.” Corr abs/2006.07756 (2020).
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Arges, Kristine, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, et al. “The Project Baseline Health Study: a step towards a broader mission to map human health.” Npj Digit Med 3 (2020): 84. https://doi.org/10.1038/s41746-020-0290-y.Full Text Open Access Copy Link to Item
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Sniderman, Allan D., George Thanassoulis, and Michael Pencina. “Letter by Sniderman et al Regarding Article, "Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease".” Circulation 140, no. 24 (December 10, 2019): e822–23. https://doi.org/10.1161/CIRCULATIONAHA.119.042776.Full Text Link to Item
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Brennan, J Matthew, Lisa Wruck, Michael J. Pencina, Robert M. Clare, Renato D. Lopes, John H. Alexander, Sean O’Brien, et al. “Claims-based cardiovascular outcome identification for clinical research: Results from 7 large randomized cardiovascular clinical trials.” Am Heart J 218 (December 2019): 110–22. https://doi.org/10.1016/j.ahj.2019.09.002.Full Text Link to Item
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Chlebus, Krzysztof, Tomasz Zdrojewski, Marcin Gruchała, Rafał Gałąska, Marcin Pajkowski, Marzena Romanowska- Kocejko, Magdalena Chmara, and Michael J. Pencina. “Cardiovascular risk factor profiles in familial hypercholesterolemia patients with and without genetic mutation compared to a nationally representative sample of adults in a high-risk European country.” Am Heart J 218 (December 2019): 32–45. https://doi.org/10.1016/j.ahj.2019.09.007.Full Text Link to Item
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Edmonston, Daniel, Daniel Wojdyla, Rupal Mehta, Xuan Cai, Claudia Lora, Debbie Cohen, Raymond R. Townsend, et al. “Single Measurements of Carboxy-Terminal Fibroblast Growth Factor 23 and Clinical Risk Prediction of Adverse Outcomes in CKD.” Am J Kidney Dis 74, no. 6 (December 2019): 771–81. https://doi.org/10.1053/j.ajkd.2019.05.026.Full Text Link to Item
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Sniderman, Allan D., George Thanassoulis, Tamara Glavinovic, Ann Marie Navar, Michael Pencina, Alberico Catapano, and Brian A. Ference. “Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review.” Jama Cardiol 4, no. 12 (December 1, 2019): 1287–95. https://doi.org/10.1001/jamacardio.2019.3780.Full Text Link to Item
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Piotrowicz, Ewa, Ryszard Piotrowicz, Grzegorz Opolski, Michael Pencina, Maciej Banach, and Wojciech Zaręba. “Hybrid comprehensive telerehabilitation in heart failure patients (TELEREH-HF): A randomized, multicenter, prospective, open-label, parallel group controlled trial-Study design and description of the intervention.” Am Heart J 217 (November 2019): 148–58. https://doi.org/10.1016/j.ahj.2019.08.015.Full Text Link to Item
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Kohli-Lynch, Ciaran N., Brandon K. Bellows, George Thanassoulis, Yiyi Zhang, Mark J. Pletcher, Eric Vittinghoff, Michael J. Pencina, Dhruv Kazi, Allan D. Sniderman, and Andrew E. Moran. “Cost-effectiveness of Low-density Lipoprotein Cholesterol Level-Guided Statin Treatment in Patients With Borderline Cardiovascular Risk.” Jama Cardiol 4, no. 10 (October 1, 2019): 969–77. https://doi.org/10.1001/jamacardio.2019.2851.Full Text Link to Item
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Xian, Ying, Haolin Xu, Emily C. O’Brien, Shreyansh Shah, Laine Thomas, Michael J. Pencina, Gregg C. Fonarow, et al. “Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” Jama Neurol 76, no. 10 (October 1, 2019): 1192–1202. https://doi.org/10.1001/jamaneurol.2019.2099.Full Text Open Access Copy Link to Item
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Enserro, Danielle M., Olga V. Demler, Michael J. Pencina, and Ralph B. D’Agostino. “Measures for evaluation of prognostic improvement under multivariate normality for nested and nonnested models.” Stat Med 38, no. 20 (September 10, 2019): 3817–31. https://doi.org/10.1002/sim.8204.Full Text Link to Item
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Mazidi, Mohsen, Niki Katsiki, Dimitri P. Mikhailidis, Michael J. Pencina, and Maciej Banach. “Egg Consumption and Risk of Total and Cause-Specific Mortality: An Individual-Based Cohort Study and Pooling Prospective Studies on Behalf of the Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group.” Journal of the American College of Nutrition 38, no. 6 (August 2019): 552–63. https://doi.org/10.1080/07315724.2018.1534620.Full Text Open Access Copy
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Pencina, Karol M., George Thanassoulis, John T. Wilkins, Ramachandran S. Vasan, Ann Marie Navar, Eric D. Peterson, Michael J. Pencina, and Allan D. Sniderman. “Trajectories of Non-HDL Cholesterol Across Midlife: Implications for Cardiovascular Prevention.” J Am Coll Cardiol 74, no. 1 (July 9, 2019): 70–79. https://doi.org/10.1016/j.jacc.2019.04.047.Full Text Link to Item
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Thomas, Laine E., Emily C. O’Brien, Jonathan P. Piccini, Ralph B. D’Agostino, and Michael J. Pencina. “Application of net reclassification index to non-nested and point-based risk prediction models: a review.” Eur Heart J 40, no. 23 (June 14, 2019): 1880–87. https://doi.org/10.1093/eurheartj/ehy345.Full Text Link to Item
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Pencina, Michael J., Chirag R. Parikh, Paul L. Kimmel, Nancy R. Cook, Josef Coresh, Harold I. Feldman, Andrea Foulkes, et al. “Statistical methods for building better biomarkers of chronic kidney disease.” Stat Med 38, no. 11 (May 20, 2019): 1903–17. https://doi.org/10.1002/sim.8091.Full Text Link to Item
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Sniderman, Allan D., Michael Pencina, and George Thanassoulis. “ApoB.” Circ Res 124, no. 10 (May 10, 2019): 1425–27. https://doi.org/10.1161/CIRCRESAHA.119.315019.Full Text Link to Item
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Goldstein, Benjamin A., Matthew Phelan, Neha J. Pagidipati, Rury R. Holman, Michael J. Pencina, and Elizabeth A. Stuart. “An outcome model approach to transporting a randomized controlled trial results to a target population.” J Am Med Inform Assoc 26, no. 5 (May 1, 2019): 429–37. https://doi.org/10.1093/jamia/ocy188.Full Text Link to Item
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Navar, Ann Marie, Eric D. Peterson, Dylan L. Steen, Daniel M. Wojdyla, Robert J. Sanchez, Irfan Khan, Xue Song, Matthew E. Gold, and Michael J. Pencina. “Evaluation of Mortality Data From the Social Security Administration Death Master File for Clinical Research.” Jama Cardiol 4, no. 4 (April 1, 2019): 375–79. https://doi.org/10.1001/jamacardio.2019.0198.Full Text Link to Item
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Pencina, Michael J., Ann Marie Navar, Daniel Wojdyla, Robert J. Sanchez, Irfan Khan, Joseph Elassal, Ralph B. D’Agostino, Eric D. Peterson, and Allan D. Sniderman. “Quantifying Importance of Major Risk Factors for Coronary Heart Disease.” Circulation 139, no. 13 (March 26, 2019): 1603–11. https://doi.org/10.1161/CIRCULATIONAHA.117.031855.Full Text Link to Item
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Pennells, Lisa, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, et al. “Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.” Eur Heart J 40, no. 7 (February 14, 2019): 621–31. https://doi.org/10.1093/eurheartj/ehy653.Full Text Open Access Copy Link to Item
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Pencina, Michael J., Ewout W. Steyerberg, and Ralph B. D’Agostino. “Single-number summary and decision analytic measures can happily coexist.” Stat Med 38, no. 3 (February 10, 2019): 499–500. https://doi.org/10.1002/sim.8031.Full Text Link to Item
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O’Brien, Emily C., DaJuanicia N. Holmes, Laine Thomas, Daniel E. Singer, Gregg C. Fonarow, Kenneth W. Mahaffey, Peter R. Kowey, et al. “Incremental prognostic value of renal function for stroke prediction in atrial fibrillation.” Int J Cardiol 274 (January 1, 2019): 152–57. https://doi.org/10.1016/j.ijcard.2018.07.113.Full Text Link to Item
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Rosenstock, Julio, Vlado Perkovic, Odd Erik Johansen, Mark E. Cooper, Steven E. Kahn, Nikolaus Marx, John H. Alexander, et al. “Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial.” Jama 321, no. 1 (January 1, 2019): 69–79. https://doi.org/10.1001/jama.2018.18269.Full Text Link to Item
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Thanassoulis, George, Allan D. Sniderman, and Michael J. Pencina. “A Long-term Benefit Approach vs Standard Risk-Based Approaches for Statin Eligibility in Primary Prevention.” Jama Cardiol 3, no. 11 (November 1, 2018): 1090–95. https://doi.org/10.1001/jamacardio.2018.3476.Full Text Link to Item
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Robinson, Jennifer G., Kevin Jon Williams, Samuel Gidding, Jan Borén, Ira Tabas, Edward A. Fisher, Chris Packard, et al. “Eradicating the Burden of Atherosclerotic Cardiovascular Disease by Lowering Apolipoprotein B Lipoproteins Earlier in Life.” J Am Heart Assoc 7, no. 20 (October 16, 2018): e009778. https://doi.org/10.1161/JAHA.118.009778.Full Text Link to Item
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Edmonston, Daniel, Myles Wolf, and Michael Pencina. “Statins at Dialysis Transition-Supportive but Not Sufficient.” Jama Netw Open 1, no. 6 (October 5, 2018): e182411. https://doi.org/10.1001/jamanetworkopen.2018.2411.Full Text Link to Item
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Sniderman, Allan D., George Thanassoulis, John T. Wilkins, Curt D. Furberg, and Michael Pencina. “Sick Individuals and Sick Populations by Geoffrey Rose: Cardiovascular Prevention Updated.” J Am Heart Assoc 7, no. 19 (October 2, 2018): e010049. https://doi.org/10.1161/JAHA.118.010049.Full Text Link to Item
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Rybin, D., R. Lew, M. J. Pencina, M. Fava, and G. Doros. “Placebo Response as a Latent Characteristic: Application to Analysis of Sequential Parallel Comparison Design Studies.” Journal of the American Statistical Association 113, no. 524 (October 2, 2018): 1411–30. https://doi.org/10.1080/01621459.2017.1375930.Full Text
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Li, Jialiang, Qunqiang Feng, Jason P. Fine, Michael J. Pencina, and Ben Van Calster. “Nonparametric estimation and inference for polytomous discrimination index.” Stat Methods Med Res 27, no. 10 (October 2018): 3092–3103. https://doi.org/10.1177/0962280217692830.Full Text Link to Item
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Pagidipati, Neha J., Anne S. Hellkamp, Puza P. Sharma, Tracy Y. Wang, Gregg C. Fonarow, and Michael Pencina. “High-sensitivity C-reactive protein elevation in patients with prior myocardial infarction in the United States.” Am Heart J 204 (October 2018): 151–55. https://doi.org/10.1016/j.ahj.2018.07.014.Full Text Link to Item
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Pencina, Karol M., Ralph B. D’Agostino, Ramachandran S. Vasan, and Michael J. Pencina. “Microsimulation model to predict incremental value of biomarkers added to prognostic models.” J Am Med Inform Assoc 25, no. 10 (October 1, 2018): 1382–85. https://doi.org/10.1093/jamia/ocy108.Full Text Link to Item
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Carin, Lawrence, and Michael J. Pencina. “On Deep Learning for Medical Image Analysis.” Jama 320, no. 11 (September 18, 2018): 1192–93. https://doi.org/10.1001/jama.2018.13316.Full Text Link to Item
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Pencina, Michael J., Frank W. Rockhold, and Ralph B. D’Agostino. “Deriving Real-World Insights From Real-World Data: Biostatistics to the Rescue.” Ann Intern Med 169, no. 6 (September 18, 2018): 401–2. https://doi.org/10.7326/M18-1093.Full Text Open Access Copy Link to Item
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Navar, Ann Marie, Michael J. Pencina, Hillary Mulder, Pierre Elias, and Eric D. Peterson. “Improving patient risk communication: Translating cardiovascular risk into standardized risk percentiles.” Am Heart J 198 (April 2018): 18–24. https://doi.org/10.1016/j.ahj.2017.12.005.Full Text Link to Item
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Rosenstock, Julio, Vlado Perkovic, John H. Alexander, Mark E. Cooper, Nikolaus Marx, Michael J. Pencina, Robert D. Toto, et al. “Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk.” Cardiovasc Diabetol 17, no. 1 (March 14, 2018): 39. https://doi.org/10.1186/s12933-018-0682-3.Full Text Open Access Copy Link to Item
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Leening, Maarten J. G., and Michael J. Pencina. “Absolute vs Additive Net Reclassification Index.” Jama 319, no. 6 (February 13, 2018): 616. https://doi.org/10.1001/jama.2017.20541.Full Text Link to Item
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Isakova, Tamara, Xuan Cai, Jungwha Lee, Dawei Xie, Xue Wang, Rupal Mehta, Norrina B. Allen, et al. “Longitudinal FGF23 Trajectories and Mortality in Patients with CKD.” J Am Soc Nephrol 29, no. 2 (February 2018): 579–90. https://doi.org/10.1681/ASN.2017070772.Full Text Link to Item
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Pencina, Michael J., Jonathan Chipman, Ewout W. Steyerberg, Danielle Braun, Jason P. Fine, and Ralph B. D’Agostino. “Authors' response to comments.” Stat Med 36, no. 28 (December 10, 2017): 4511–13. https://doi.org/10.1002/sim.7520.Full Text Link to Item
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Pencina, Michael J., Ewout W. Steyerberg, and Ralph B. D’Agostino. “Net reclassification index at event rate: properties and relationships.” Stat Med 36, no. 28 (December 10, 2017): 4455–67. https://doi.org/10.1002/sim.7041.Full Text Link to Item
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Pencina, Michael J., Jason P. Fine, and Ralph B. D’Agostino. “Discrimination slope and integrated discrimination improvement - properties, relationships and impact of calibration.” Stat Med 36, no. 28 (December 10, 2017): 4482–90. https://doi.org/10.1002/sim.7139.Full Text Link to Item
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Burstein, Barry, Kathleen K. Altobelli, Ken Williams, Christopher P. Cannon, Michael J. Pencina, Allan D. Sniderman, and George Thanassoulis. “Impact of Heart Outcomes Prevention Evaluation Trial on Statin Eligibility for the Primary Prevention of Cardiovascular Disease: Insights from the National Health and Nutrition Examination Survey.” Circulation 136, no. 19 (November 7, 2017): 1860–62. https://doi.org/10.1161/CIRCULATIONAHA.117.029102.Full Text Link to Item
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Thanassoulis, George, Michael J. Pencina, and Allan D. Sniderman. “The Benefit Model for Prevention of Cardiovascular Disease: An Opportunity to Harmonize Guidelines.” Jama Cardiol 2, no. 11 (November 1, 2017): 1175–76. https://doi.org/10.1001/jamacardio.2017.2543.Full Text Link to Item
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Demler, Olga V., Michael J. Pencina, Nancy R. Cook, and Ralph B. D’Agostino. “Asymptotic distribution of ∆AUC, NRIs, and IDI based on theory of U-statistics.” Stat Med 36, no. 21 (September 20, 2017): 3334–60. https://doi.org/10.1002/sim.7333.Full Text Link to Item
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Pagidipati, Neha J., Ann Marie Navar, and Michael J. Pencina. “Guideline Recommendations for Statin Therapy-Reply.” Jama 318, no. 10 (September 12, 2017): 964. https://doi.org/10.1001/jama.2017.11379.Full Text Link to Item
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Awad, Kamal, Dimitri P. Mikhailidis, Peter P. Toth, Steven R. Jones, Patrick Moriarty, Gregory Y. H. Lip, Paul Muntner, et al. “Efficacy and Safety of Alternate-Day Versus Daily Dosing of Statins: a Systematic Review and Meta-Analysis.” Cardiovasc Drugs Ther 31, no. 4 (August 2017): 419–31. https://doi.org/10.1007/s10557-017-6743-0.Full Text Link to Item
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Calis, Karim A., Patrick Archdeacon, Raymond Bain, David DeMets, Miriam Donohue, M Khair Elzarrad, Annemarie Forrest, et al. “Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative.” Clin Trials 14, no. 4 (August 2017): 342–48. https://doi.org/10.1177/1740774517707743.Full Text Link to Item
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Goldstein, Benjamin A., Gina Maria Pomann, Wolfgang C. Winkelmayer, and Michael J. Pencina. “A comparison of risk prediction methods using repeated observations: an application to electronic health records for hemodialysis.” Stat Med 36, no. 17 (July 30, 2017): 2750–63. https://doi.org/10.1002/sim.7308.Full Text Link to Item
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Brennan, J Matthew, Laine Thomas, David J. Cohen, David Shahian, Alice Wang, Michael J. Mack, David R. Holmes, et al. “Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison.” J Am Coll Cardiol 70, no. 4 (July 25, 2017): 439–50. https://doi.org/10.1016/j.jacc.2017.05.060.Full Text Link to Item
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Li, J., J. P. Fine, and M. J. Pencina. “Multi-category diagnostic accuracy based on logistic regression.” Statistical Theory and Related Fields 1, no. 2 (July 3, 2017): 143–58. https://doi.org/10.1080/24754269.2017.1319105.Full Text
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Nagarajan, Vijaiganesh, Gregg C. Fonarow, Christine Ju, Michael Pencina, Warren K. Laskey, Thomas M. Maddox, Adrian Hernandez, and Deepak L. Bhatt. “Seasonal and circadian variations of acute myocardial infarction: Findings from the Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) program.” Am Heart J 189 (July 2017): 85–93. https://doi.org/10.1016/j.ahj.2017.04.002.Full Text Link to Item
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Hoffmann, Udo, Maros Ferencik, James E. Udelson, Michael H. Picard, Quynh A. Truong, Manesh R. Patel, Megan Huang, et al. “Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain: Insights From the PROMISE Trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain).” Circulation 135, no. 24 (June 13, 2017): 2320–32. https://doi.org/10.1161/CIRCULATIONAHA.116.024360.Full Text Link to Item
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Fleming, Thomas R., David L. DeMets, Matthew T. Roe, Janet Wittes, Karim A. Calis, Amit N. Vora, Alan Meisel, et al. “Rejoinder.” Clin Trials 14, no. 2 (April 2017): 126–27. https://doi.org/10.1177/1740774516688917.Full Text Link to Item
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Fleming, Thomas R., David L. DeMets, Matthew T. Roe, Janet Wittes, Karim A. Calis, Amit N. Vora, Alan Meisel, et al. “Data monitoring committees: Promoting best practices to address emerging challenges.” Clin Trials 14, no. 2 (April 2017): 115–23. https://doi.org/10.1177/1740774516688915.Full Text Link to Item
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Pagidipati, Neha J., Ann Marie Navar, Hillary Mulder, Allan D. Sniderman, Eric D. Peterson, and Michael J. Pencina. “Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines.” Jama 317, no. 15 (April 2017): 1563–67. https://doi.org/10.1001/jama.2017.3416.Full Text
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Spratt, Susan E., Katherine Pereira, Bradi B. Granger, Bryan C. Batch, Matthew Phelan, Michael Pencina, Marie Lynn Miranda, et al. “Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus.” J Am Med Inform Assoc 24, no. e1 (April 1, 2017): e121–28. https://doi.org/10.1093/jamia/ocw123.Full Text Link to Item
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Xian, Ying, Emily C. O’Brien, Li Liang, Haolin Xu, Lee H. Schwamm, Gregg C. Fonarow, Deepak L. Bhatt, et al. “Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation.” Jama 317, no. 10 (March 14, 2017): 1057–67. https://doi.org/10.1001/jama.2017.1371.Full Text Open Access Copy Link to Item
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Kopeć, Grzegorz, Marcin Waligóra, Anna Tyrka, Kamil Jonas, Michael J. Pencina, Tomasz Zdrojewski, Deddo Moertl, Jakub Stokwiszewski, Paweł Zagożdżon, and Piotr Podolec. “Low-density lipoprotein cholesterol and survival in pulmonary arterial hypertension.” Scientific Reports 7 (February 2017): 41650. https://doi.org/10.1038/srep41650.Full Text Open Access Copy
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Gopalakrishna, Gowri, Miranda Langendam, Rob Scholten, Patrick Bossuyt, Mariska Leeflang, Anna Noel-Storr, James Thomas, et al. “Erratum to: Methods for evaluating medical tests and biomarkers.” Diagn Progn Res 1 (2017): 11. https://doi.org/10.1186/s41512-017-0011-4.Full Text Open Access Copy Link to Item
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Goldstein, Benjamin A., Ann Marie Navar, Michael J. Pencina, and John P. A. Ioannidis. “Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review.” Journal of the American Medical Informatics Association : Jamia 24, no. 1 (January 2017): 198–208. https://doi.org/10.1093/jamia/ocw042.Full Text
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Goldstein, Benjamin A., Michael J. Pencina, Maria E. Montez-Rath, and Wolfgang C. Winkelmayer. “Predicting mortality over different time horizons: which data elements are needed?” J Am Med Inform Assoc 24, no. 1 (January 2017): 176–81. https://doi.org/10.1093/jamia/ocw057.Full Text Link to Item
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Sharma, Abhinav, Robert H. Bigelow, and Michael J. Pencina. “Scientific, societal, and economic consequences of releasing interim data from clinical trials.” Eur Heart J Qual Care Clin Outcomes 3, no. 1 (January 1, 2017): 9–10. https://doi.org/10.1093/ehjqcco/qcw037.Full Text Link to Item
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Stolker, Joshua M., David J. Cohen, Kevin F. Kennedy, Michael J. Pencina, Suzanne V. Arnold, Neal S. Kleiman, John A. Spertus, and John A. EVENT Investigators. “Combining clinical and angiographic variables for estimating risk of target lesion revascularization after drug eluting stent placement.” Cardiovasc Revasc Med 18, no. 3 (2017): 169–76. https://doi.org/10.1016/j.carrev.2016.12.014.Full Text Link to Item
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Robinson, Jennifer G., Roeland Huijgen, Kausik Ray, Jane Persons, John J. P. Kastelein, and Michael J. Pencina. “Determining When to Add Nonstatin Therapy: A Quantitative Approach.” J Am Coll Cardiol 68, no. 22 (December 6, 2016): 2412–21. https://doi.org/10.1016/j.jacc.2016.09.928.Full Text Link to Item
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Wilson, Peter W. F., and Michael J. Pencina. “Estimation of Risk for Initial Atherosclerotic Cardiovascular Disease Events: Taking Stock and Moving Forward.” Circulation 134, no. 23 (December 6, 2016): 1792–93. https://doi.org/10.1161/CIRCULATIONAHA.116.025026.Full Text Link to Item
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Thomas, Laine E., and Michael J. Pencina. “Do Not Over (P) Value Your Research Article.” Jama Cardiol 1, no. 9 (December 1, 2016): 1055. https://doi.org/10.1001/jamacardio.2016.3827.Full Text Link to Item
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Barnhart, Huiman X., Eric Yow, Anna Lisa Crowley, Melissa A. Daubert, Dawn Rabineau, Robert Bigelow, Michael Pencina, and Pamela S. Douglas. “Choice of agreement indices for assessing and improving measurement reproducibility in a core laboratory setting.” Stat Methods Med Res 25, no. 6 (December 2016): 2939–58. https://doi.org/10.1177/0962280214534651.Full Text Link to Item
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Crowley, Anna Lisa, Eric Yow, Huiman X. Barnhart, Melissa A. Daubert, Robert Bigelow, Daniel C. Sullivan, Michael Pencina, and Pamela S. Douglas. “Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research.” J Am Soc Echocardiogr 29, no. 12 (December 2016): 1144-1154.e7. https://doi.org/10.1016/j.echo.2016.08.006.Full Text Open Access Copy Link to Item
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Goldstein, Benjamin A., Ann Marie Navar, and Michael J. Pencina. “Risk Prediction With Electronic Health Records: The Importance of Model Validation and Clinical Context.” Jama Cardiol 1, no. 9 (December 1, 2016): 976–77. https://doi.org/10.1001/jamacardio.2016.3826.Full Text Link to Item
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Goldstein, Benjamin A., Nrupen A. Bhavsar, Matthew Phelan, and Michael J. Pencina. “Controlling for Informed Presence Bias Due to the Number of Health Encounters in an Electronic Health Record.” American Journal of Epidemiology 184, no. 11 (December 2016): 847–55. https://doi.org/10.1093/aje/kww112.Full Text
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Pandey, Ambarish, Harsh Golwala, Haolin Xu, Adam D. DeVore, Roland Matsouaka, Michael Pencina, Dharam J. Kumbhani, et al. “Association of 30-Day Readmission Metric for Heart Failure Under the Hospital Readmissions Reduction Program With Quality of Care and Outcomes.” Jacc Heart Fail 4, no. 12 (December 2016): 935–46. https://doi.org/10.1016/j.jchf.2016.07.003.Full Text Link to Item
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Navar, Ann Marie, Eric D. Peterson, Daniel Wojdyla, Robert J. Sanchez, Allan D. Sniderman, Ralph B. D’Agostino, and Michael J. Pencina. “Temporal Changes in the Association Between Modifiable Risk Factors and Coronary Heart Disease Incidence.” Jama 316, no. 19 (November 15, 2016): 2041–43. https://doi.org/10.1001/jama.2016.13614.Full Text Link to Item
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Ngwa, J. S., H. J. Cabral, D. M. Cheng, M. J. Pencina, D. R. Gagnon, M. P. LaValley, and L. A. Cupples. “A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study.” Bmc Medical Research Methodology 16, no. 1 (November 3, 2016): 148.
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Ngwa, Julius S., Howard J. Cabral, Debbie M. Cheng, Michael J. Pencina, David R. Gagnon, Michael P. LaValley, and L Adrienne Cupples. “A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study.” Bmc Med Res Methodol 16, no. 1 (November 3, 2016): 148. https://doi.org/10.1186/s12874-016-0248-6.Full Text Link to Item
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Hornik, Christoph P., Daniel K. Benjamin, P Brian Smith, Michael J. Pencina, Adriana H. Tremoulet, Edmund V. Capparelli, Jessica E. Ericson, Reese H. Clark, Michael Cohen-Wolkowiez, and Michael Best Pharmaceuticals for Children Act—Pediatric Trials Network. “Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates.” J Pediatr 178 (November 2016): 125-129.e1. https://doi.org/10.1016/j.jpeds.2016.07.011.Full Text Link to Item
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Navar, Ann Marie, Michael J. Pencina, and Eric D. Peterson. “Assessing Cardiovascular Risk to Guide Hypertension Diagnosis and Treatment.” Jama Cardiol 1, no. 8 (November 1, 2016): 864–71. https://doi.org/10.1001/jamacardio.2016.2861.Full Text Link to Item
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Sniderman, Allan D., Shofiqul Islam, Matthew McQueen, Michael Pencina, Curt D. Furberg, George Thanassoulis, and Salim Yusuf. “Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low-Density Lipoprotein Cholesterol or Non-High-Density Lipoprotein Cholesterol.” J Am Heart Assoc 5, no. 10 (October 13, 2016). https://doi.org/10.1161/JAHA.116.003665.Full Text Link to Item
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Chruściel, Piotr, Amirhossein Sahebkar, Magdalena Rembek-Wieliczko, Maria-Corina Serban, Sorin Ursoniu, Dimitri P. Mikhailidis, Steven R. Jones, et al. “Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms.” Atherosclerosis 253 (October 2016): 194–208. https://doi.org/10.1016/j.atherosclerosis.2016.07.897.Full Text Link to Item
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O’Brien, Emily C., Ying Xian, Haolin Xu, Jingjing Wu, Jeffrey L. Saver, Eric E. Smith, Lee H. Schwamm, et al. “Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research).” Stroke 47, no. 10 (October 2016): 2627–33. https://doi.org/10.1161/STROKEAHA.116.013563.Full Text Link to Item
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Lee, Jerry C., Tomasz Zdrojewski, Michael J. Pencina, Adam Wyszomirski, Mateusz Lachacz, Grzegorz Opolski, Piotr Bandosz, et al. “Population Effect of Differences in Cholesterol Guidelines in Eastern Europe and the United States.” Jama Cardiol 1, no. 6 (September 1, 2016): 700–707. https://doi.org/10.1001/jamacardio.2016.1585.Full Text Link to Item
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Navar, Ann Marie, Michael J. Pencina, and Eric D. Peterson. “Open Access Platforms for Sharing Clinical Trial Data--Reply.” Jama 316, no. 6 (August 9, 2016): 666–67. https://doi.org/10.1001/jama.2016.8797.Full Text Link to Item
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Clement, Meredith E., Lawrence P. Park, Ann Marie Navar, Nwora Lance Okeke, Michael J. Pencina, Pamela S. Douglas, and Susanna Naggie. “Statin Utilization and Recommendations Among HIV- and HCV-infected Veterans: A Cohort Study.” Clin Infect Dis 63, no. 3 (August 1, 2016): 407–13. https://doi.org/10.1093/cid/ciw289.Full Text Link to Item
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Sniderman, Allan D., George Thanassoulis, Ken Williams, and Michael Pencina. “Risk of Premature Cardiovascular Disease vs the Number of Premature Cardiovascular Events.” Jama Cardiol 1, no. 4 (July 1, 2016): 492–94. https://doi.org/10.1001/jamacardio.2016.0991.Full Text Link to Item
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Banach, Maciej, Maria-Corina Serban, Amirhossein Sahebkar, Hector M. García-García, Dimitri P. Mikhailidis, Seth S. Martin, Daniel Brie, et al. “Comparison of clinical outcomes between bioresorbable vascular stents versus conventional drug-eluting and metallic stents: a systematic review and meta-analysis.” Eurointervention 12, no. 2 (June 12, 2016): e175–89. https://doi.org/10.4244/EIJY16M06_02.Full Text Link to Item
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Van Calster, Ben, Daan Nieboer, Yvonne Vergouwe, Bavo De Cock, Michael J. Pencina, and Ewout W. Steyerberg. “A calibration hierarchy for risk models was defined: from utopia to empirical data.” J Clin Epidemiol 74 (June 2016): 167–76. https://doi.org/10.1016/j.jclinepi.2015.12.005.Full Text Link to Item
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Mentz, Robert J., L Kristin Newby, Ben Neely, Joseph E. Lucas, Sean D. Pokorney, Meena P. Rao, Larry R. Jackson, et al. “Assessment of Administrative Data to Identify Acute Myocardial Infarction in Electronic Health Records.” J Am Coll Cardiol 67, no. 20 (May 24, 2016): 2441–42. https://doi.org/10.1016/j.jacc.2016.03.511.Full Text Link to Item
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McGuire, Darren K., Frans Van de Werf, Paul W. Armstrong, Eberhard Standl, Joerg Koglin, Jennifer B. Green, M Angelyn Bethel, et al. “Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 1, no. 2 (May 1, 2016): 126–35. https://doi.org/10.1001/jamacardio.2016.0103.Full Text Link to Item
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Pagidipati, Neha J., Michael Pencina, and Allan D. Sniderman. “The Enigma of Glucose and Lipid Metabolism.” Jama Cardiol 1, no. 2 (May 1, 2016): 145–46. https://doi.org/10.1001/jamacardio.2016.0183.Full Text Link to Item
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Pencina, Michael J., and Eric D. Peterson. “Moving From Clinical Trials to Precision Medicine: The Role for Predictive Modeling.” Jama 315, no. 16 (April 26, 2016): 1713–14. https://doi.org/10.1001/jama.2016.4839.Full Text Link to Item
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Thanassoulis, George, Ken Williams, Kathleen Kimler Altobelli, Michael J. Pencina, Christopher P. Cannon, and Allan D. Sniderman. “Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease.” Circulation 133, no. 16 (April 19, 2016): 1574–81. https://doi.org/10.1161/CIRCULATIONAHA.115.018383.Full Text Link to Item
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Banovic, Marko, Bernard Iung, Jozef Bartunek, Milika Asanin, Branko Beleslin, Bojan Biocina, Filip Casselman, et al. “Rationale and design of the Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): A randomized multicenter controlled event-driven trial.” Am Heart J 174 (April 2016): 147–53. https://doi.org/10.1016/j.ahj.2016.02.001.Full Text Link to Item
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Fox, Ervin R., Tandaw E. Samdarshi, Solomon K. Musani, Michael J. Pencina, Jung Hye Sung, Alain G. Bertoni, Vanessa Xanthakis, et al. “Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort.” Jama Cardiol 1, no. 1 (April 1, 2016): 15–25. https://doi.org/10.1001/jamacardio.2015.0300.Full Text Link to Item
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Holman, Rury R., Mary Angelyn Bethel, Jyothis George, Harald Sourij, Zoë Doran, Joanne Keenan, Nardev S. Khurmi, et al. “Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial.” Am Heart J 174 (April 2016): 103–10. https://doi.org/10.1016/j.ahj.2015.12.009.Full Text Link to Item
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Navar, Ann Marie, Michael J. Pencina, Jennifer A. Rymer, Darcy M. Louzao, and Eric D. Peterson. “Use of Open Access Platforms for Clinical Trial Data.” Jama 315, no. 12 (March 22, 2016): 1283–84. https://doi.org/10.1001/jama.2016.2374.Full Text Link to Item
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Pencina, Michael J., Darcy M. Louzao, Brian J. McCourt, Monique R. Adams, Rehbar H. Tayyabkhan, Peter Ronco, and Eric D. Peterson. “Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative.” Am Heart J 172 (February 2016): 64–69. https://doi.org/10.1016/j.ahj.2015.11.002.Full Text Link to Item
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Sahebkar, Amirhossein, Maria-Corina Serban, Dimitri P. Mikhailidis, Peter P. Toth, Paul Muntner, Sorin Ursoniu, Svetlana Mosterou, et al. “Head-to-head comparison of statins versus fibrates in reducing plasma fibrinogen concentrations: A systematic review and meta-analysis.” Pharmacol Res 103 (January 2016): 236–52. https://doi.org/10.1016/j.phrs.2015.12.001.Full Text Link to Item
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Zdrojewski, Tomasz, Bogdan Solnica, Barbara Cybulska, Piotr Bandosz, Marcin Rutkowski, Jakub Stokwiszewski, Zbigniew Gaciong, et al. “Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey.” Kardiol Pol 74, no. 3 (2016): 213–23. https://doi.org/10.5603/KP.2016.0029.Full Text Link to Item
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“The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.” European Heart Journal 36, no. 46 (December 7, 2015): 3258–64. https://doi.org/10.1093/eurheartj/ehv476.Full Text
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O’Brien, Emily C., DaJuanicia N. Simon, Laine E. Thomas, Elaine M. Hylek, Bernard J. Gersh, Jack E. Ansell, Peter R. Kowey, et al. “The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.” Eur Heart J 36, no. 46 (December 7, 2015): 3258–64. https://doi.org/10.1093/eurheartj/ehv476.Full Text Open Access Copy Link to Item
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Shelton, Richard C., Michael J. Pencina, Lori W. Barrentine, Juan A. Ruiz, Maurizio Fava, John M. Zajecka, and George I. Papakostas. “Association of obesity and inflammatory marker levels on treatment outcome: results from a double-blind, randomized study of adjunctive L-methylfolate calcium in patients with MDD who are inadequate responders to SSRIs.” J Clin Psychiatry 76, no. 12 (December 2015): 1635–41. https://doi.org/10.4088/JCP.14m09587.Full Text Link to Item
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Sniderman, Allan D., Ralph B. D’Agostino, and Michael J. Pencina. “Risk Prediction for Individuals--Reply.” Jama 314, no. 17 (November 3, 2015): 1875–76. https://doi.org/10.1001/jama.2015.12221.Full Text Link to Item
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Wu, Li-Tzy, Udi E. Ghitza, Bryan C. Batch, Michael J. Pencina, Leoncio Flavio Rojas, Benjamin A. Goldstein, Tony Schibler, Ashley A. Dunham, Shelley Rusincovitch, and Kathleen T. Brady. “Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data.” Drug Alcohol Depend 156 (November 1, 2015): 162–69. https://doi.org/10.1016/j.drugalcdep.2015.09.003.Full Text Open Access Copy Link to Item
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Wechsler, Michael E., Barbara P. Yawn, Anne L. Fuhlbrigge, Wilson D. Pace, Michael J. Pencina, Gheorghe Doros, Shamsah Kazani, et al. “Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial.” Jama 314, no. 16 (October 27, 2015): 1720–30. https://doi.org/10.1001/jama.2015.13277.Full Text Link to Item
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Navar-Boggan, Ann Marie, Eric D. Peterson, Ralph B. D’Agostino, Benjamin Neely, Allan D. Sniderman, and Michael J. Pencina. “Response to Letter Regarding Article, "Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease".” Circulation 132, no. 16 (October 20, 2015): e203. https://doi.org/10.1161/CIRCULATIONAHA.115.017048.Full Text Link to Item
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O’Brien, Emily C., Melissa A. Greiner, Ying Xian, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” Circulation 132, no. 15 (October 13, 2015): 1404–13. https://doi.org/10.1161/CIRCULATIONAHA.115.016183.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, Tomasz Zdrojewski, Ken Williams, George Thanassoulis, Curt D. Furberg, Eric D. Peterson, Ramachandran S. Vasan, and Allan D. Sniderman. “Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C.” Eur J Prev Cardiol 22, no. 10 (October 2015): 1321–27. https://doi.org/10.1177/2047487315569411.Full Text Link to Item
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Sinning, Jan-Malte, Kai C. Wollert, Alexander Sedaghat, Christian Widera, Marie-Caroline Radermacher, Claire Descoups, Christoph Hammerstingl, et al. “Risk scores and biomarkers for the prediction of 1-year outcome after transcatheter aortic valve replacement.” Am Heart J 170, no. 4 (October 2015): 821–29. https://doi.org/10.1016/j.ahj.2015.07.003.Full Text Link to Item
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Pencina, Michael J., and Ralph B. D’Agostino. “Evaluating Discrimination of Risk Prediction Models: The C Statistic.” Jama 314, no. 10 (September 8, 2015): 1063–64. https://doi.org/10.1001/jama.2015.11082.Full Text Link to Item
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Ko, Min Jung, Yun Jung Kim, Chan Mi Park, Sun-Mi Lee, Woo Je Lee, Michael J. Pencina, Ann Marie Navar-Boggan, and Duk-Woo Park. “Applicability and potential clinical effects of 2013 cholesterol guidelines on major cardiovascular events.” Am Heart J 170, no. 3 (September 2015): 598-605.e7. https://doi.org/10.1016/j.ahj.2015.06.012.Full Text Link to Item
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Jansen, Henning, Christina Loley, Wolfgang Lieb, Michael J. Pencina, Christopher P. Nelson, Sekar Kathiresan, Gina M. Peloso, et al. “Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.” Atherosclerosis 241, no. 2 (August 2015): 419–26. https://doi.org/10.1016/j.atherosclerosis.2015.05.033.Full Text Link to Item
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Min, James K., Allison Dunning, Heidi Gransar, Stephan Achenbach, Fay Y. Lin, Mouaz Al-Mallah, Matthew J. Budoff, et al. “Medical history for prognostic risk assessment and diagnosis of stable patients with suspected coronary artery disease.” Am J Med 128, no. 8 (August 2015): 871–78. https://doi.org/10.1016/j.amjmed.2014.10.031.Full Text Link to Item
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Fine, Jason P., and Michael Pencina. “On the quantitative assessment of predictive biomarkers.” J Natl Cancer Inst 107, no. 8 (August 2015). https://doi.org/10.1093/jnci/djv187.Full Text Link to Item
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Xian, Ying, Jingjing Wu, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Real world effectiveness of warfarin among ischemic stroke patients with atrial fibrillation: observational analysis from Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) study.” Bmj 351 (July 31, 2015): h3786. https://doi.org/10.1136/bmj.h3786.Full Text Open Access Copy Link to Item
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Navar, Ann Marie, and Michael Pencina. “ACP Journal Club. In adults without CV disease, most prediction scores overestimated risk for atherosclerotic CV events.” Ann Intern Med 163, no. 2 (July 21, 2015): JC13. https://doi.org/10.7326/ACPJC-2015-163-2-013.Full Text Link to Item
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Green, Jennifer B., M Angelyn Bethel, Paul W. Armstrong, John B. Buse, Samuel S. Engel, Jyotsna Garg, Robert Josse, et al. “Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes.” N Engl J Med 373, no. 3 (July 16, 2015): 232–42. https://doi.org/10.1056/NEJMoa1501352.Full Text Link to Item
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Rybin, Denis, Gheorghe Doros, Michael J. Pencina, and Maurizio Fava. “Placebo non-response measure in sequential parallel comparison design studies.” Stat Med 34, no. 15 (July 10, 2015): 2281–93. https://doi.org/10.1002/sim.6494.Full Text Link to Item
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Sniderman, Allan D., Ralph B. D’Agostino, and Michael J. Pencina. “The Role of Physicians in the Era of Predictive Analytics.” Jama 314, no. 1 (July 7, 2015): 25–26. https://doi.org/10.1001/jama.2015.6177.Full Text Link to Item
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Goff, David C., Ralph B. D’Agostino, Michael Pencina, and Donald M. Lloyd-Jones. “Calibration and Discrimination Among Multiple Cardiovascular Risk Scores in a Modern Multiethnic Cohort.” Ann Intern Med 163, no. 1 (July 7, 2015): 68. https://doi.org/10.7326/L15-5105.Full Text Link to Item
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Steyerberg, Ewout W., Moniek M. Vedder, Maarten J. G. Leening, Douwe Postmus, Ralph B. D’Agostino, Ben Van Calster, and Michael J. Pencina. “Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives.” Biom J 57, no. 4 (July 2015): 556–70. https://doi.org/10.1002/bimj.201300260.Full Text Link to Item
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Xian, Ying, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deidre Hannah, Brianna Lindholm, et al. “Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research: Implementing the patient-driven research paradigm to aid decision making in stroke care.” Am Heart J 170, no. 1 (July 2015): 36-45.11. https://doi.org/10.1016/j.ahj.2015.04.008.Full Text Link to Item
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Sniderman, Allan D., Michael Pencina, and George Thanassoulis. “Limitations in the conventional assessment of the incremental value of predictors of cardiovascular risk.” Curr Opin Lipidol 26, no. 3 (June 2015): 210–14. https://doi.org/10.1097/MOL.0000000000000181.Full Text Link to Item
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Navar-Boggan, Ann Marie, Eric D. Peterson, Ralph B. D’Agostino, Michael J. Pencina, and Allan D. Sniderman. “Using age- and sex-specific risk thresholds to guide statin therapy: one size may not fit all.” J Am Coll Cardiol 65, no. 16 (April 28, 2015): 1633–39. https://doi.org/10.1016/j.jacc.2015.02.025.Full Text Link to Item
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Bandosz, Piotr, Martin O’Flaherty, Marcin Rutkowski, Chris Kypridemos, Maria Guzman-Castillo, Duncan O. S. Gillespie, Bogdan Solnica, et al. “A victory for statins or a defeat for diet policies? Cholesterol falls in Poland in the past decade: A modeling study.” Int J Cardiol 185 (April 15, 2015): 313–19. https://doi.org/10.1016/j.ijcard.2015.03.079.Full Text Link to Item
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Mühlenbruch, Kristin, Olga Kuxhaus, Michael J. Pencina, Heiner Boeing, Hannelore Liero, and Matthias B. Schulze. “A confidence ellipse for the Net Reclassification Improvement.” Eur J Epidemiol 30, no. 4 (April 2015): 299–304. https://doi.org/10.1007/s10654-015-0001-1.Full Text Link to Item
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Abraham, Tobin M., Karol M. Pencina, Michael J. Pencina, and Caroline S. Fox. “Trends in diabetes incidence: the Framingham Heart Study.” Diabetes Care 38, no. 3 (March 2015): 482–87. https://doi.org/10.2337/dc14-1432.Full Text Link to Item
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Navar-Boggan, Ann Marie, Eric D. Peterson, Ralph B. D’Agostino, Benjamin Neely, Allan D. Sniderman, and Michael J. Pencina. “Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.” Circulation 131, no. 5 (February 3, 2015): 451–58. https://doi.org/10.1161/CIRCULATIONAHA.114.012477.Full Text Link to Item
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Dallmeier, Dhayana, Michael J. Pencina, Iris Rajman, Wolfgang Koenig, Dietrich Rothenbacher, and Hermann Brenner. “Serial measurements of N-terminal pro-brain natriuretic peptide in patients with coronary heart disease.” Plos One 10, no. 1 (2015): e0117143. https://doi.org/10.1371/journal.pone.0117143.Full Text Link to Item
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Magnani, Jared W., Lei Zhu, Faye Lopez, Michael J. Pencina, Sunil K. Agarwal, Elsayed Z. Soliman, Emelia J. Benjamin, and Alvaro Alonso. “P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study.” Am Heart J 169, no. 1 (January 2015): 53-61.e1. https://doi.org/10.1016/j.ahj.2014.10.009.Full Text Link to Item
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Pencina, Michael J., Benjamin Neely, and Ewout W. Steyerberg. “RE: net risk reclassification P Values: valid or misleading?” J Natl Cancer Inst 107, no. 1 (January 2015): 355. https://doi.org/10.1093/jnci/dju355.Full Text Link to Item
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Shao, Fang, Jialiang Li, Jason Fine, Weng Kee Wong, and Michael Pencina. “Inference for reclassification statistics under nested and non-nested models for biomarker evaluation.” Biomarkers 20, no. 4 (2015): 240–52. https://doi.org/10.3109/1354750X.2015.1068854.Full Text Link to Item
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Pencina, Karol M., Michael J. Pencina, and Ralph B. D’Agostino. “What to expect from net reclassification improvement with three categories.” Stat Med 33, no. 28 (December 10, 2014): 4975–87. https://doi.org/10.1002/sim.6286.Full Text Link to Item
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Rutkowski, M., P. Bandosz, L. Czupryniak, Z. Gaciong, B. Solnica, H. Jasiel-Wojculewicz, B. Wyrzykowski, M. J. Pencina, and T. Zdrojewski. “Prevalence of diabetes and impaired fasting glucose in Poland--the NATPOL 2011 Study.” Diabet Med 31, no. 12 (December 2014): 1568–71. https://doi.org/10.1111/dme.12542.Full Text Link to Item
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Clark, Cari Jo, Alvaro Alonso, Rachael A. Spencer, Michael Pencina, Ken Williams, and Susan A. Everson-Rose. “Predicted long-term cardiovascular risk among young adults in the national longitudinal study of adolescent health.” Am J Public Health 104, no. 12 (December 2014): e108–15. https://doi.org/10.2105/AJPH.2014.302148.Full Text Link to Item
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Ahmad, Tariq, Michael J. Pencina, Phillip J. Schulte, Emily O’Brien, David J. Whellan, Ileana L. Piña, Dalane W. Kitzman, Kerry L. Lee, Christopher M. O’Connor, and G Michael Felker. “Clinical implications of chronic heart failure phenotypes defined by cluster analysis.” J Am Coll Cardiol 64, no. 17 (October 28, 2014): 1765–74. https://doi.org/10.1016/j.jacc.2014.07.979.Full Text Link to Item
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Ahmad, Tariq, Mona Fiuzat, Michael J. Pencina, Nancy L. Geller, Faiez Zannad, John G. F. Cleland, James V. Snider, et al. “Charting a roadmap for heart failure biomarker studies.” Jacc Heart Fail 2, no. 5 (October 2014): 477–88. https://doi.org/10.1016/j.jchf.2014.02.005.Full Text Link to Item
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Boone, M Dustin, Leo A. Celi, Ben G. Ho, Michael Pencina, Michael P. Curry, Yotam Lior, Daniel Talmor, and Victor Novack. “Model for End-Stage Liver Disease score predicts mortality in critically ill cirrhotic patients.” J Crit Care 29, no. 5 (October 2014): 881.e7-881.13. https://doi.org/10.1016/j.jcrc.2014.05.013.Full Text Link to Item
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Sinner, Moritz F., Katherine A. Stepas, Carlee B. Moser, Bouwe P. Krijthe, Thor Aspelund, Nona Sotoodehnia, João D. Fontes, et al. “B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies.” Europace 16, no. 10 (October 2014): 1426–33. https://doi.org/10.1093/europace/euu175.Full Text Link to Item
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Baker, Stuart G., Ewoud Schuit, Ewout W. Steyerberg, Michael J. Pencina, Andrew Vickers, Karel G. M. Moons, Ben W. J. Mol, and Karen S. Lindeman. “How to interpret a small increase in AUC with an additional risk prediction marker: decision analysis comes through.” Stat Med 33, no. 22 (September 28, 2014): 3946–59. https://doi.org/10.1002/sim.6195.Full Text Link to Item
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Leening, Maarten J. G., Ewout W. Steyerberg, Ben Van Calster, Ralph B. D’Agostino, and Michael J. Pencina. “Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective.” Stat Med 33, no. 19 (August 30, 2014): 3415–18. https://doi.org/10.1002/sim.6133.Full Text Link to Item
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Navar-Boggan, Ann Marie, Michael J. Pencina, and Eric D. Peterson. “Patients affected by changes to hypertension guideline--reply.” Jama 312, no. 8 (August 27, 2014): 846–47. https://doi.org/10.1001/jama.2014.9882.Full Text Link to Item
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Chan, Raymond H., Barry J. Maron, Iacopo Olivotto, Michael J. Pencina, Gabriele Egidy Assenza, Tammy Haas, John R. Lesser, et al. “Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy.” Circulation 130, no. 6 (August 5, 2014): 484–95. https://doi.org/10.1161/CIRCULATIONAHA.113.007094.Full Text Link to Item
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Hess, Connie N., Matthew T. Roe, C Michael Gibson, Robert J. Temple, Michael J. Pencina, Deborah A. Zarin, Kevin J. Anstrom, et al. “Independent data monitoring committees: preparing a path for the future.” Am Heart J 168, no. 2 (August 2014): 135-41.e1. https://doi.org/10.1016/j.ahj.2014.05.003.Full Text Link to Item
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Marino, Miguel, Yi Li, Michael J. Pencina, Ralph B. D’Agostino, Lisa F. Berkman, and Orfeu M. Buxton. “Quantifying cardiometabolic risk using modifiable non-self-reported risk factors.” Am J Prev Med 47, no. 2 (August 2014): 131–40. https://doi.org/10.1016/j.amepre.2014.03.006.Full Text Link to Item
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Xanthakis, Vanessa, Lisa M. Sullivan, Ramachandran S. Vasan, Emelia J. Benjamin, Joseph M. Massaro, Ralph B. D’Agostino, and Michael J. Pencina. “Assessing the incremental predictive performance of novel biomarkers over standard predictors.” Stat Med 33, no. 15 (July 10, 2014): 2577–84. https://doi.org/10.1002/sim.6165.Full Text Link to Item
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Navar-Boggan, Ann Marie, Allan D. Sniderman, and Michael J. Pencina. “Application of the new cholesterol guidelines.” N Engl J Med 371, no. 1 (July 3, 2014): 79. https://doi.org/10.1056/NEJMc1405680.Full Text Link to Item
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Michalska, Marta, Jacek Rysz, Michael J. Pencina, Tomasz Zdrojewski, and Maciej Banach. “The knowledge and awareness of hypertension among patients with hypertension in central Poland: a pilot registry.” Angiology 65, no. 6 (July 2014): 525–32. https://doi.org/10.1177/0003319713489166.Full Text Link to Item
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Pen, Ally, Yeung Yam, Li Chen, Sharmila Dorbala, Marcelo F. Di Carli, Michael E. Merhige, Brent A. Williams, et al. “Prognostic value of Rb-82 positron emission tomography myocardial perfusion imaging in coronary artery bypass patients.” Eur Heart J Cardiovasc Imaging 15, no. 7 (July 2014): 787–92. https://doi.org/10.1093/ehjci/jet259.Full Text Link to Item
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Vardi, Moshe, Gregory Piazza, Michael J. Pencina, David A. Burke, Lanyu Lei, Samuel Z. Goldhaber, and Donald E. Cutlip. “Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention.” Clin Appl Thromb Hemost 20, no. 5 (July 2014): 478–83. https://doi.org/10.1177/1076029613517166.Full Text Link to Item
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Piotrowicz, Ewa, Michael Pencina, Walerian Piotrowski, Maciej Banach, and Ryszard Piotrowicz. “Influence of exercise training on T-wave alternans assessed during exercise test in heart failure patients.” Int J Cardiol 174, no. 3 (July 1, 2014): 747–49. https://doi.org/10.1016/j.ijcard.2014.04.088.Full Text Link to Item
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Bangalore, Sripal, Michael J. Pencina, Neal S. Kleiman, and David J. Cohen. “Heparin monotherapy or bivalirudin during percutaneous coronary intervention in patients with non-ST-segment-elevation acute coronary syndromes or stable ischemic heart disease: results from the Evaluation of Drug-Eluting Stents and Ischemic Events registry.” Circ Cardiovasc Interv 7, no. 3 (June 2014): 365–73. https://doi.org/10.1161/CIRCINTERVENTIONS.113.001126.Full Text Link to Item
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Ahmad, Tariq, Mona Fiuzat, Benjamin Neely, Megan L. Neely, Michael J. Pencina, William E. Kraus, Faiez Zannad, et al. “Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure.” Jacc Heart Fail 2, no. 3 (June 2014): 260–68. https://doi.org/10.1016/j.jchf.2013.12.004.Full Text Link to Item
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Sniderman, Allan D., Peter P. Toth, George Thanassoulis, Michael J. Pencina, and Curt D. Furberg. “Taking a longer term view of cardiovascular risk: the causal exposure paradigm.” Bmj 348 (May 21, 2014): g3047. https://doi.org/10.1136/bmj.g3047.Full Text Link to Item
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Van Calster, Ben, Ewout W. Steyerberg, Ralph B. D’Agostino, and Michael J. Pencina. “Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models.” Med Decis Making 34, no. 4 (May 2014): 513–22. https://doi.org/10.1177/0272989X13513654.Full Text Link to Item
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Vardi, Moshe, Victor Novack, Michael J. Pencina, Gheorghe Doros, David A. Burke, Sammy Elmariah, Donald E. Cutlip, Laura Mauri, and Robert W. Yeh. “Safety and efficacy metrics for primary nitinol stenting in femoropopliteal occlusive disease: a meta-analysis and critical examination of current methodologies.” Catheter Cardiovasc Interv 83, no. 6 (May 1, 2014): 975–83. https://doi.org/10.1002/ccd.25179.Full Text Link to Item
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Pencina, Michael J., Ann Marie Navar-Boggan, Ralph B. D’Agostino, Ken Williams, Benjamin Neely, Allan D. Sniderman, and Eric D. Peterson. “Application of new cholesterol guidelines to a population-based sample.” N Engl J Med 370, no. 15 (April 10, 2014): 1422–31. https://doi.org/10.1056/NEJMoa1315665.Full Text Link to Item
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Navar-Boggan, Ann Marie, Michael J. Pencina, Ken Williams, Allan D. Sniderman, and Eric D. Peterson. “Proportion of US adults potentially affected by the 2014 hypertension guideline.” Jama 311, no. 14 (April 9, 2014): 1424–29. https://doi.org/10.1001/jama.2014.2531.Full Text Link to Item
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Chow, Benjamin J. W., Sharmila Dorbala, Marcelo F. Di Carli, Michael E. Merhige, Brent A. Williams, Emir Veledar, James K. Min, et al. “Prognostic value of PET myocardial perfusion imaging in obese patients.” Jacc Cardiovasc Imaging 7, no. 3 (March 2014): 278–87. https://doi.org/10.1016/j.jcmg.2013.12.008.Full Text Link to Item
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Fox, Caroline S., Michael J. Pencina, Nancy L. Heard-Costa, Peter Shrader, Cashell Jaquish, Christopher J. O’Donnell, Ramachandran S. Vasan, L Adrienne Cupples, and Ralph B. D’Agostino. “Trends in the association of parental history of obesity over 60 years.” Obesity (Silver Spring) 22, no. 3 (March 2014): 919–24. https://doi.org/10.1002/oby.20564.Full Text Link to Item
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Ren, Xiushui, Nader M. Banki, Richard E. Shaw, Edward J. McNulty, Sherry C. Williams, Michael Pencina, and Nelson B. Schiller. “Doppler-detected valve movement in aortic stenosis: a predictor of adverse outcome.” Clin Cardiol 37, no. 3 (March 2014): 167–71. https://doi.org/10.1002/clc.22236.Full Text Link to Item
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Baker, S. G., E. Schuit, E. W. Steyerberg, M. J. Pencina, A. Vickers, K. G. M. Moons, B. W. J. Mol, and K. S. Lindeman. “Correction to How to interpret a small increase in AUC with an additional risk prediction marker: Decision analysis comes through [Statist. Med. (2015) 33, 22, 3946-3959] DOI: 10.1002/sim.6195.” Statistics in Medicine 34, no. 5 (February 28, 2014): 900. https://doi.org/10.1002/sim.6330.Full Text
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Leening, Maarten J. G., Moniek M. Vedder, Jacqueline C. M. Witteman, Michael J. Pencina, and Ewout W. Steyerberg. “Net reclassification improvement: computation, interpretation, and controversies: a literature review and clinician's guide.” Ann Intern Med 160, no. 2 (January 21, 2014): 122–31. https://doi.org/10.7326/M13-1522.Full Text Link to Item
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Avriel, Avital, Maya Paryente Wiessman, Yaniv Almog, Yael Perl, Victor Novack, Ori Galante, Moti Klein, Michael J. Pencina, and Amos Douvdevani. “Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care.” Plos One 9, no. 6 (2014): e100514. https://doi.org/10.1371/journal.pone.0100514.Full Text Link to Item
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Velagaleti, Raghava S., Philimon Gona, Michael J. Pencina, Jayashri Aragam, Thomas J. Wang, Daniel Levy, Ralph B. D’Agostino, et al. “Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction.” Am J Cardiol 113, no. 1 (January 1, 2014): 117–22. https://doi.org/10.1016/j.amjcard.2013.09.028.Full Text Link to Item
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Kemp, D. E., L. G. Sylvia, J. R. Calabrese, A. A. Nierenberg, M. E. Thase, N. A. Reilly-Harrington, M. J. Ostacher, et al. “General medical burden in bipolar disorder: findings from the LiTMUS comparative effectiveness trial.” Acta Psychiatr Scand 129, no. 1 (January 2014): 24–34. https://doi.org/10.1111/acps.12101.Full Text Link to Item
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Bangalore, Sripal, Michael J. Pencina, Neal S. Kleiman, and David J. Cohen. “Prognostic implications of procedural vs spontaneous myocardial infarction: results from the Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry.” Am Heart J 166, no. 6 (December 2013): 1027–34. https://doi.org/10.1016/j.ahj.2013.09.008.Full Text Link to Item
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Vardi, Moshe, David A. Burke, Sripal Bangalore, Michael J. Pencina, Laura Mauri, David E. Kandzari, Martin B. Leon, and Donald E. Cutlip. “Long-term efficacy and safety of Zotarolimus-eluting stent in patients with diabetes mellitus: pooled 5-year results from the ENDEAVOR III and IV trials.” Catheter Cardiovasc Interv 82, no. 7 (December 1, 2013): 1031–38. https://doi.org/10.1002/ccd.25045.Full Text Link to Item
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Demler, Olga V., Michael J. Pencina, and Ralph B. D’Agostino. “Impact of correlation on predictive ability of biomarkers.” Stat Med 32, no. 24 (October 30, 2013): 4196–4210. https://doi.org/10.1002/sim.5824.Full Text Link to Item
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Nikolic, Dragana, Maciej Banach, Shekoufeh Nikfar, Pooneh Salari, Dimitri P. Mikhailidis, Peter P. Toth, Mohammad Abdollahi, et al. “A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important?” Int J Cardiol 168, no. 6 (October 15, 2013): 5437–47. https://doi.org/10.1016/j.ijcard.2013.08.060.Full Text Link to Item
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Banach, Maciej, Shekoufeh Nikfar, Roja Rahimi, Agata Bielecka-Dabrowa, Michael J. Pencina, Dimitri P. Mikhailidis, Krzysztof Narkiewicz, et al. “The effects of statins on blood pressure in normotensive or hypertensive subjects--a meta-analysis of randomized controlled trials.” Int J Cardiol 168, no. 3 (October 3, 2013): 2816–24. https://doi.org/10.1016/j.ijcard.2013.03.068.Full Text Link to Item
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Widera, Christian, Michael J. Pencina, Maria Bobadilla, Ines Reimann, Anja Guba-Quint, Ivonne Marquardt, Kerstin Bethmann, et al. “Incremental prognostic value of biomarkers beyond the GRACE (Global Registry of Acute Coronary Events) score and high-sensitivity cardiac troponin T in non-ST-elevation acute coronary syndrome.” Clin Chem 59, no. 10 (October 2013): 1497–1505. https://doi.org/10.1373/clinchem.2013.206185.Full Text Link to Item
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Berry, Sarah D., Elizabeth J. Samelson, Michael J. Pencina, Robert R. McLean, L Adrienne Cupples, Kerry E. Broe, and Douglas P. Kiel. “Repeat bone mineral density screening and prediction of hip and major osteoporotic fracture.” Jama 310, no. 12 (September 25, 2013): 1256–62. https://doi.org/10.1001/jama.2013.277817.Full Text Link to Item
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Lubitz, Steven A., Carlee Moser, Lisa Sullivan, Michiel Rienstra, João D. Fontes, Mark L. Villalon, Manju Pai, et al. “Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community.” J Am Heart Assoc 2, no. 5 (September 3, 2013): e000126. https://doi.org/10.1161/JAHA.113.000126.Full Text Link to Item
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Dording, Christina, Clair Cassiello, Franklin King, Michael Pencina, Maurizio Fava, and David Mischoulon. “The effects of aripiprazole on the subscales of the Kellner Symptom Questionnaire in treatment resistant depression.” Int Clin Psychopharmacol 28, no. 5 (September 2013): 238–44. https://doi.org/10.1097/YIC.0b013e32836220df.Full Text Link to Item
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Vickers, Andrew J., and Michael J. Pencina. “Prostate-specific antigen velocity: new methods, same results, still no evidence of clinical utility.” Eur Urol 64, no. 3 (September 2013): 394–96. https://doi.org/10.1016/j.eururo.2013.03.003.Full Text Link to Item
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Califf, Robert M., and Michael J. Pencina. “Predictive models in heart failure: who cares?” Circ Heart Fail 6, no. 5 (September 1, 2013): 877–78. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000659.Full Text Link to Item
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Shah, Ravi, Bobak Heydari, Otavio Coelho-Filho, Venkatesh L. Murthy, Siddique Abbasi, Jiazhuo H. Feng, Michael Pencina, et al. “Stress cardiac magnetic resonance imaging provides effective cardiac risk reclassification in patients with known or suspected stable coronary artery disease.” Circulation 128, no. 6 (August 6, 2013): 605–14. https://doi.org/10.1161/CIRCULATIONAHA.113.001430.Full Text Link to Item
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Schnabel, Renate B., Michiel Rienstra, Lisa M. Sullivan, Jenny X. Sun, Carlee B. Moser, Daniel Levy, Michael J. Pencina, et al. “Risk assessment for incident heart failure in individuals with atrial fibrillation.” Eur J Heart Fail 15, no. 8 (August 2013): 843–49. https://doi.org/10.1093/eurjhf/hft041.Full Text Link to Item
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Doros, Gheorghe, Michael Pencina, Denis Rybin, Allison Meisner, and Maurizio Fava. “A repeated measures model for analysis of continuous outcomes in sequential parallel comparison design studies.” Stat Med 32, no. 16 (July 20, 2013): 2767–89. https://doi.org/10.1002/sim.5728.Full Text Link to Item
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Barylski, Marcin, Shekoufeh Nikfar, Dimitri P. Mikhailidis, Peter P. Toth, Pooneh Salari, Kausik K. Ray, Michael J. Pencina, et al. “Statins decrease all-cause mortality only in CKD patients not requiring dialysis therapy--a meta-analysis of 11 randomized controlled trials involving 21,295 participants.” Pharmacol Res 72 (June 2013): 35–44. https://doi.org/10.1016/j.phrs.2013.03.007.Full Text Link to Item
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Preis, Sarah Rosner, Michael J. Pencina, Devin M. Mann, Ralph B. D’Agostino, Peter J. Savage, and Caroline S. Fox. “Early-adulthood cardiovascular disease risk factor profiles among individuals with and without diabetes in the Framingham Heart Study.” Diabetes Care 36, no. 6 (June 2013): 1590–96. https://doi.org/10.2337/dc12-1121.Full Text Link to Item
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Jasuja, Guneet Kaur, Thomas G. Travison, Maithili Davda, Joanne M. Murabito, Shehzad Basaria, Anqi Zhang, Mark M. Kushnir, et al. “Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study.” J Gerontol a Biol Sci Med Sci 68, no. 6 (June 2013): 733–40. https://doi.org/10.1093/gerona/gls216.Full Text Link to Item
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Lieb, Wolfgang, Henning Jansen, Christina Loley, Michael J. Pencina, Christopher P. Nelson, Christopher Newton-Cheh, Sekar Kathiresan, et al. “Genetic predisposition to higher blood pressure increases coronary artery disease risk.” Hypertension 61, no. 5 (May 2013): 995–1001. https://doi.org/10.1161/HYPERTENSIONAHA.111.00275.Full Text Link to Item
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Menon, S., J. Massaro, M. J. Pencina, J. Lewis, and Y. C. Wang. “Comparison of operating characteristics of commonly used sample size re-estimation procedures in a two-stage design.” Communications in Statistics: Simulation and Computation 42, no. 5 (May 1, 2013): 1140–52. https://doi.org/10.1080/03610918.2012.661501.Full Text
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Nikolic, Dragana, Shekoufeh Nikfar, Pooneh Salari, Manfredi Rizzo, Kausik K. Ray, Michael J. Pencina, Dimitri P. Mikhailidis, et al. “Effects of statins on lipid profile in chronic kidney disease patients: a meta-analysis of randomized controlled trials.” Curr Med Res Opin 29, no. 5 (May 2013): 435–51. https://doi.org/10.1185/03007995.2013.779237.Full Text Link to Item
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Van Calster, Ben, Andrew J. Vickers, Michael J. Pencina, Stuart G. Baker, Dirk Timmerman, and Ewout W. Steyerberg. “Evaluation of markers and risk prediction models: overview of relationships between NRI and decision-analytic measures.” Med Decis Making 33, no. 4 (May 2013): 490–501. https://doi.org/10.1177/0272989X12470757.Full Text Link to Item
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Miguel-Yanes, Jose M. de, Bianca Porneala, Michael J. Pencina, Caroline S. Fox, Jose C. Florez, David S. Siscovick, Josée Dupuis, and James B. Meigs. “Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.” J Hypertens 31, no. 5 (May 2013): 1001–9. https://doi.org/10.1097/HJH.0b013e32835f5a83.Full Text Link to Item
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Costa, Marco A., Michael Pencina, Serjan Nikolic, Thomas Engels, Barry Templin, and William T. Abraham. “The PARACHUTE IV trial design and rationale: percutaneous ventricular restoration using the parachute device in patients with ischemic heart failure and dilated left ventricles.” Am Heart J 165, no. 4 (April 2013): 531–36. https://doi.org/10.1016/j.ahj.2012.12.022.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Joseph M. Massaro. “Understanding increments in model performance metrics.” Lifetime Data Anal 19, no. 2 (April 2013): 202–18. https://doi.org/10.1007/s10985-012-9238-0.Full Text Link to Item
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Alonso, Alvaro, Bouwe P. Krijthe, Thor Aspelund, Katherine A. Stepas, Michael J. Pencina, Carlee B. Moser, Moritz F. Sinner, et al. “Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium.” J Am Heart Assoc 2, no. 2 (March 18, 2013): e000102. https://doi.org/10.1161/JAHA.112.000102.Full Text Link to Item
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Clair, Carole, Nancy A. Rigotti, Bianca Porneala, Caroline S. Fox, Ralph B. D’Agostino, Michael J. Pencina, and James B. Meigs. “Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes.” Jama 309, no. 10 (March 13, 2013): 1014–21. https://doi.org/10.1001/jama.2013.1644.Full Text Link to Item
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Boggs, Deborah A., Lynn Rosenberg, Michael J. Pencina, Lucile L. Adams-Campbell, and Julie R. Palmer. “Validation of a breast cancer risk prediction model developed for Black women.” J Natl Cancer Inst 105, no. 5 (March 6, 2013): 361–67. https://doi.org/10.1093/jnci/djt008.Full Text Link to Item
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D’Agostino, Ralph B., Michael J. Pencina, Joseph M. Massaro, and Sean Coady. “Cardiovascular Disease Risk Assessment: Insights from Framingham.” Glob Heart 8, no. 1 (March 2013): 11–23. https://doi.org/10.1016/j.gheart.2013.01.001.Full Text Link to Item
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Matthan, Nirupa R., Lei Zhu, Michael Pencina, Ralph B. D’Agostino, Ernst J. Schaefer, and Alice H. Lichtenstein. “Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants.” J Am Heart Assoc 2, no. 1 (February 19, 2013): e005066. https://doi.org/10.1161/JAHA.112.005066.Full Text Link to Item
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Dorbala, Sharmila, Marcelo F. Di Carli, Rob S. Beanlands, Michael E. Merhige, Brent A. Williams, Emir Veledar, Benjamin J. W. Chow, et al. “Prognostic value of stress myocardial perfusion positron emission tomography: results from a multicenter observational registry.” J Am Coll Cardiol 61, no. 2 (January 15, 2013): 176–84. https://doi.org/10.1016/j.jacc.2012.09.043.Full Text Link to Item
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Sinner, Moritz F., Na Wang, Caroline S. Fox, João D. Fontes, Michiel Rienstra, Jared W. Magnani, Ramachandran S. Vasan, et al. “Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation.” Am J Cardiol 111, no. 2 (January 15, 2013): 219–24. https://doi.org/10.1016/j.amjcard.2012.09.021.Full Text Link to Item
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Mihaescu, Raluca, Michael J. Pencina, Alvaro Alonso, Kathryn L. Lunetta, Susan R. Heckbert, Emelia J. Benjamin, and A Cecile J. W. Janssens. “Incremental value of rare genetic variants for the prediction of multifactorial diseases.” Genome Med 5, no. 8 (2013): 76. https://doi.org/10.1186/gm480.Full Text Link to Item
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Singh, Gitanjali M., Goodarz Danaei, Farshad Farzadfar, Gretchen A. Stevens, Mark Woodward, David Wormser, Stephen Kaptoge, et al. “The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis.” Plos One 8, no. 7 (2013): e65174. https://doi.org/10.1371/journal.pone.0065174.Full Text Link to Item
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Bouchard, Danielle R., Bianca Porneala, Ian Janssen, Marie-France Langlois, Jean-Patrice Baillargeon, Caroline S. Fox, James B. Meigs, Ralph B. D’Agostino, Michael Pencina, and Marie-France Hivert. “Risk of type 2 diabetes and cumulative excess weight exposure in the Framingham Offspring Study.” J Diabetes Complications 27, no. 3 (2013): 214–18. https://doi.org/10.1016/j.jdiacomp.2012.11.009.Full Text Link to Item
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Fatemi, Omid, Jaya Paranilam, Alex Rainow, Kevin Kennedy, Jason Choi, Donald Cutlip, Michael Pencina, Peter B. Berger, David J. Cohen, and Neal S. Kleiman. “Red cell distribution width is a predictor of mortality in patients undergoing percutaneous coronary intervention.” J Thromb Thrombolysis 35, no. 1 (January 2013): 57–64. https://doi.org/10.1007/s11239-012-0767-x.Full Text Link to Item
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Nierenberg, Andrew A., Edward S. Friedman, Charles L. Bowden, Louisa G. Sylvia, Michael E. Thase, Terence Ketter, Michael J. Ostacher, et al. “Lithium treatment moderate-dose use study (LiTMUS) for bipolar disorder: a randomized comparative effectiveness trial of optimized personalized treatment with and without lithium.” Am J Psychiatry 170, no. 1 (January 2013): 102–10. https://doi.org/10.1176/appi.ajp.2012.12060751.Full Text Link to Item
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Preis, Sarah Rosner, Michael J. Pencina, Ralph B. D’Agostino, James B. Meigs, Ramachandran S. Vasan, and Caroline S. Fox. “Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study.” Diabetes Care 36, no. 1 (January 2013): e3. https://doi.org/10.2337/dc12-0738.Full Text Link to Item
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Zdrojewski, Tomasz, Marcin Rutkowski, Piotr Bandosz, Zbigniew Gaciong, Tadeusz Jędrzejczyk, Bogdan Solnica, Michał Pencina, et al. “Prevalence and control of cardiovascular risk factors in Poland. Assumptions and objectives of the NATPOL 2011 Survey.” Kardiol Pol 71, no. 4 (2013): 381–92. https://doi.org/10.5603/KP.2013.0066.Full Text Link to Item
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Papakostas, George I., Richard C. Shelton, John M. Zajecka, Bijan Etemad, Karl Rickels, Alisabet Clain, Lee Baer, et al. “L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials.” Am J Psychiatry 169, no. 12 (December 2012): 1267–74. https://doi.org/10.1176/appi.ajp.2012.11071114.Full Text Link to Item
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Stolker, Joshua M., David J. Cohen, Kevin F. Kennedy, Michael J. Pencina, Jason B. Lindsey, Laura Mauri, Donald E. Cutlip, Neal S. Kleiman, and Neal S. Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) Investigators. “Repeat revascularization after contemporary percutaneous coronary intervention: an evaluation of staged, target lesion, and other unplanned revascularization procedures during the first year.” Circ Cardiovasc Interv 5, no. 6 (December 2012): 772–82. https://doi.org/10.1161/CIRCINTERVENTIONS.111.967802.Full Text Link to Item
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Sun, Hengrui, Beth A. Davison, Gad Cotter, Michael J. Pencina, and Gary G. Koch. “Evaluating treatment efficacy by multiple end points in phase II acute heart failure clinical trials: analyzing data using a global method.” Circ Heart Fail 5, no. 6 (November 2012): 742–49. https://doi.org/10.1161/CIRCHEARTFAILURE.112.969154.Full Text Link to Item
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Vassy, Jason L., Pronabesh Dasmahapatra, James B. Meigs, Nicholas J. Schork, Costan G. Magnussen, Wei Chen, Olli T. Raitakari, et al. “Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population.” Pediatrics 130, no. 5 (November 2012): e1235–42. https://doi.org/10.1542/peds.2012-1132.Full Text Link to Item
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Demler, Olga V., Michael J. Pencina, and Ralph B. D’Agostino. “Misuse of DeLong test to compare AUCs for nested models.” Stat Med 31, no. 23 (October 15, 2012): 2577–87. https://doi.org/10.1002/sim.5328.Full Text Link to Item
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Emerging Risk Factors Collaboration, John, Stephen Kaptoge, Emanuele Di Angelantonio, Lisa Pennells, Angela M. Wood, Ian R. White, Pei Gao, et al. “C-reactive protein, fibrinogen, and cardiovascular disease prediction.” N Engl J Med 367, no. 14 (October 4, 2012): 1310–20. https://doi.org/10.1056/NEJMoa1107477.Full Text Open Access Copy Link to Item
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Ho, Jennifer E., Chunyu Liu, Asya Lyass, Paul Courchesne, Michael J. Pencina, Ramachandran S. Vasan, Martin G. Larson, and Daniel Levy. “Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community.” J Am Coll Cardiol 60, no. 14 (October 2, 2012): 1249–56. https://doi.org/10.1016/j.jacc.2012.04.053.Full Text Link to Item
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Steyerberg, E. W., M. J. Pencina, and B. Van Calster. “Discriminative ability, reclassification and net benefit: Research methodology No. 7: The predictive value of biomarkers.” Nederlands Tijdschrift Voor Geneeskunde 156, no. 43 (October 1, 2012).
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Emerging Risk Factors Collaboration, Surya T. “Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis.” Int J Epidemiol 41, no. 5 (October 2012): 1419–33. https://doi.org/10.1093/ije/dys086.Full Text Link to Item
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Min, James K., Jonathon Leipsic, Michael J. Pencina, Daniel S. Berman, Bon-Kwon Koo, Carlos van Mieghem, Andrejs Erglis, et al. “Diagnostic accuracy of fractional flow reserve from anatomic CT angiography.” Jama 308, no. 12 (September 26, 2012): 1237–45. https://doi.org/10.1001/2012.jama.11274.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, Olga V. Demler, A Cecile J. W. Janssens, and Philip Greenland. “Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution".” Am J Epidemiol 176, no. 6 (September 15, 2012): 492–94. https://doi.org/10.1093/aje/kws206.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, Karol M. Pencina, A Cecile J. W. Janssens, and Philip Greenland. “Interpreting incremental value of markers added to risk prediction models.” Am J Epidemiol 176, no. 6 (September 15, 2012): 473–81. https://doi.org/10.1093/aje/kws207.Full Text Link to Item
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Polak, Joseph F., Allison Meisner, Michael J. Pencina, Philip A. Wolf, and Ralph B. D’Agostino. “Variations in common carotid artery intima-media thickness during the cardiac cycle: implications for cardiovascular risk assessment.” J Am Soc Echocardiogr 25, no. 9 (September 2012): 1023–28. https://doi.org/10.1016/j.echo.2012.05.007.Full Text Link to Item
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D’Agostino, Ralph B., and Michael J. Pencina. “Invited commentary: Clinical usefulness of the Framingham cardiovascular risk profile beyond its statistical performance.” Am J Epidemiol 176, no. 3 (August 1, 2012): 187–89. https://doi.org/10.1093/aje/kws203.Full Text Link to Item
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Pencina, Michael J. “Caution is needed in the interpretation of added value of biomarkers analyzed in matched case control studies.” Clin Chem 58, no. 8 (August 2012): 1176–78. https://doi.org/10.1373/clinchem.2012.188383.Full Text Link to Item
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Brautbar, Ariel, Lisa A. Pompeii, Abbas Dehghan, Julius S. Ngwa, Vijay Nambi, Salim S. Virani, Fernando Rivadeneira, et al. “A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies.” Atherosclerosis 223, no. 2 (August 2012): 421–26. https://doi.org/10.1016/j.atherosclerosis.2012.05.035.Full Text Link to Item
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Caputo, Ronald P., Ankush Goel, Michael Pencina, David J. Cohen, Neal S. Kleiman, Chen-Hsing Yen, Ron Waksman, et al. “Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry).” Am J Cardiol 110, no. 3 (August 1, 2012): 350–55. https://doi.org/10.1016/j.amjcard.2012.03.031.Full Text Link to Item
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Cho, Iksung, Hyuk-Jae Chang, Ji Min Sung, Michael J. Pencina, Fay Y. Lin, Allison M. Dunning, Stephan Achenbach, et al. “Coronary computed tomographic angiography and risk of all-cause mortality and nonfatal myocardial infarction in subjects without chest pain syndrome from the CONFIRM Registry (coronary CT angiography evaluation for clinical outcomes: an international multicenter registry).” Circulation 126, no. 3 (July 17, 2012): 304–13. https://doi.org/10.1161/CIRCULATIONAHA.111.081380.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Linye Song. “Quantifying discrimination of Framingham risk functions with different survival C statistics.” Stat Med 31, no. 15 (July 10, 2012): 1543–53. https://doi.org/10.1002/sim.4508.Full Text Link to Item
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Ho, Jennifer E., Philimon Gona, Michael J. Pencina, Jack V. Tu, Peter C. Austin, Ramachandran S. Vasan, William B. Kannel, Ralph B. D’Agostino, Douglas S. Lee, and Daniel Levy. “Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community.” Eur Heart J 33, no. 14 (July 2012): 1734–41. https://doi.org/10.1093/eurheartj/ehs070.Full Text Link to Item
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Wilson, Peter W. F., Ralph D’Agostino, Deepak L. Bhatt, Kim Eagle, Michael J. Pencina, Sidney C. Smith, Mark J. Alberts, et al. “An international model to predict recurrent cardiovascular disease.” Am J Med 125, no. 7 (July 2012): 695-703.e1. https://doi.org/10.1016/j.amjmed.2012.01.014.Full Text Link to Item
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Fava, M., D. Mischoulon, D. Iosifescu, J. Witte, M. Pencina, M. Flynn, L. Harper, M. Levy, K. Rickels, and M. Pollack. “A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A study):(Psychotherapy and Psychosomatics (2012) 81, (87-97)).” Psychotherapy and Psychosomatics 81, no. 4 (June 1, 2012): 261. https://doi.org/10.1159/000337702.Full Text
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Rana, Jamal S., Heidi Gransar, Nathan D. Wong, Leslee Shaw, Michael Pencina, Khurram Nasir, Alan Rozanski, et al. “Comparative value of coronary artery calcium and multiple blood biomarkers for prognostication of cardiovascular events.” Am J Cardiol 109, no. 10 (May 15, 2012): 1449–53. https://doi.org/10.1016/j.amjcard.2012.01.358.Full Text Link to Item
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Widera, Christian, Michael J. Pencina, Allison Meisner, Tibor Kempf, Kerstin Bethmann, Ivonne Marquardt, Hugo A. Katus, Evangelos Giannitsis, and Kai C. Wollert. “Adjustment of the GRACE score by growth differentiation factor 15 enables a more accurate appreciation of risk in non-ST-elevation acute coronary syndrome.” Eur Heart J 33, no. 9 (May 2012): 1095–1104. https://doi.org/10.1093/eurheartj/ehr444.Full Text Link to Item
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Pencina, Michael J., and Ralph B. D’Agostino. “Thoroughly modern risk prediction?” Sci Transl Med 4, no. 131 (April 25, 2012): 131fs10. https://doi.org/10.1126/scitranslmed.3004127.Full Text Link to Item
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Boggs, Deborah A., Lynn Rosenberg, Michael J. Pencina, and Julie R. Palmer. “Abstract LB-327: Validation of a breast cancer risk prediction model in African American women.” Cancer Research 72, no. 8_Supplement (April 15, 2012). https://doi.org/10.1158/1538-7445.am2012-lb-327.Full Text
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Novack, Victor, Michael Pencina, David J. Cohen, Neal S. Kleiman, Chen-Hsing Yen, Jorge F. Saucedo, Peter B. Berger, and Donald E. Cutlip. “Troponin criteria for myocardial infarction after percutaneous coronary intervention.” Arch Intern Med 172, no. 6 (March 26, 2012): 502–8. https://doi.org/10.1001/archinternmed.2011.2275.Full Text Link to Item
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Prushik, Scott G., Alik Farber, Philimon Gona, Peter Shrader, Michael J. Pencina, Ralph B. D’Agostino, and Joanne M. Murabito. “Parental intermittent claudication as risk factor for claudication in adults.” Am J Cardiol 109, no. 5 (March 1, 2012): 736–41. https://doi.org/10.1016/j.amjcard.2011.10.032.Full Text Link to Item
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Mischoulon, David, Janet Witte, Michael Levy, George I. Papakostas, L Russell Pet, Wen-hua Hsieh, Michael J. Pencina, Sean Ward, Mark H. Pollack, and Maurizio Fava. “Efficacy of dose increase among nonresponders to low-dose aripiprazole augmentation in patients with inadequate response to antidepressant treatment: a randomized, double-blind, placebo-controlled, efficacy trial.” J Clin Psychiatry 73, no. 3 (March 2012): 353–57. https://doi.org/10.4088/JCP.10m06541.Full Text Link to Item
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Dording, Christina M., Elizabeth D. Dalton, Michael J. Pencina, Maurizio Fava, and David Mischoulon. “Comparison of academic and nonacademic sites in multi-center clinical trials.” J Clin Psychopharmacol 32, no. 1 (February 2012): 65–68. https://doi.org/10.1097/JCP.0b013e31823f3b47.Full Text Link to Item
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Steyerberg, Ewout W., Michael J. Pencina, Hester F. Lingsma, Michael W. Kattan, Andrew J. Vickers, and Ben Van Calster. “Assessing the incremental value of diagnostic and prognostic markers: a review and illustration.” Eur J Clin Invest 42, no. 2 (February 2012): 216–28. https://doi.org/10.1111/j.1365-2362.2011.02562.x.Full Text Link to Item
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Thanassoulis, George, Gina M. Peloso, Michael J. Pencina, Udo Hoffmann, Caroline S. Fox, L Adrienne Cupples, Daniel Levy, Ralph B. D’Agostino, Shih-Jen Hwang, and Christopher J. O’Donnell. “A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.” Circ Cardiovasc Genet 5, no. 1 (February 1, 2012): 113–21. https://doi.org/10.1161/CIRCGENETICS.111.961342.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Olga V. Demler. “Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models.” Stat Med 31, no. 2 (January 30, 2012): 101–13. https://doi.org/10.1002/sim.4348.Full Text Link to Item
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Rapsomaniki, Eleni, Ian R. White, Angela M. Wood, Simon G. Thompson, and Simon G. Emerging Risk Factors Collaboration. “A framework for quantifying net benefits of alternative prognostic models.” Stat Med 31, no. 2 (January 30, 2012): 114–30. https://doi.org/10.1002/sim.4362.Full Text Link to Item
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Pencina, M. J., R. B. D’Agostino, and E. W. Steyerberg. “Authors' reply.” Statistics in Medicine 31, no. 1 (January 13, 2012): 96–97. https://doi.org/10.1002/sim.4428.Full Text
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Polak, Joseph F., and Michael J. Pencina. “Measuring carotid artery intima-media thickness: simplicity versus complexity?” J Am Soc Echocardiogr 25, no. 1 (January 2012): 101–4. https://doi.org/10.1016/j.echo.2011.11.004.Full Text Link to Item
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Steyerberg, E. W., M. J. Pencina, and B. V. Calster. “Discriminative ability, reclassification and net benefit: Research methodology No. 7: The predictive value of biomarkers.” Nederlands Tijdschrift Voor Geneeskunde 156, no. 43 (2012).
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Steyerberg, E. W., M. J. Pencina, and B. Van Calster. “[Discriminative ability, reclassification and net benefit: the predictive value of biomarkers].” Nederlands Tijdschrift Voor Geneeskunde 156, no. 41 (January 1, 2012).
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Steyerberg, Ewout W., Michael J. Pencina, and Ben Van Calster. “[Discriminative ability, reclassification and net benefit: the predictive value of biomarkers].” Ned Tijdschr Geneeskd 156, no. 41 (2012): A5029.Link to Item
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Fava, Maurizio, David Mischoulon, Dan Iosifescu, Janet Witte, Michael Pencina, Martina Flynn, Linda Harper, Michael Levy, Karl Rickels, and Mark Pollack. “A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A Study).” Psychother Psychosom 81, no. 2 (2012): 87–97. https://doi.org/10.1159/000332050.Full Text Link to Item
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Murphy, Timothy P., Rajoo Dhangana, Michael J. Pencina, and Ralph B. D’Agostino. “Ankle-brachial index and cardiovascular risk prediction: an analysis of 11,594 individuals with 10-year follow-up.” Atherosclerosis 220, no. 1 (January 2012): 160–67. https://doi.org/10.1016/j.atherosclerosis.2011.10.037.Full Text Link to Item
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Mega, Jessica L., Willibald Hochholzer, Andrew L. Frelinger, Michael J. Kluk, Dominick J. Angiolillo, Dean J. Kereiakes, Steven Isserman, et al. “Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease.” Jama 306, no. 20 (November 23, 2011): 2221–28. https://doi.org/10.1001/jama.2011.1703.Full Text Link to Item
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Murthy, Venkatesh L., Masanao Naya, Courtney R. Foster, Jon Hainer, Mariya Gaber, Gilda Di Carli, Ron Blankstein, et al. “Improved cardiac risk assessment with noninvasive measures of coronary flow reserve.” Circulation 124, no. 20 (November 15, 2011): 2215–24. https://doi.org/10.1161/CIRCULATIONAHA.111.050427.Full Text Link to Item
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Bhasin, Shalender, Guneet K. Jasjua, Michael Pencina, Ralph D’Agostino, Andrea D. Coviello, Ramachandran S. Vasan, and Thomas G. Travison. “Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study.” Diabetes Care 34, no. 11 (November 2011): 2464–70. https://doi.org/10.2337/dc11-0888.Full Text Link to Item
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Mauri, Laura, Sharon-Lise T. Normand, Michael Pencina, Donald E. Cutlip, Cathy Jeon, Paul Dreyer, Richard E. Kuntz, Donald S. Baim, and Alice K. Jacobs. “Rationale and design of the MASS COMM trial: A randomized trial to compare percutaneous coronary intervention between MASSachusetts hospitals with cardiac surgery on-site and COMMunity hospitals without cardiac surgery on-site.” Am Heart J 162, no. 5 (November 2011): 826–31. https://doi.org/10.1016/j.ahj.2011.08.018.Full Text Link to Item
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Polak, Joseph F., Michael J. Pencina, Daniel H. O’Leary, and Ralph B. D’Agostino. “Common carotid artery intima-media thickness progression as a predictor of stroke in multi-ethnic study of atherosclerosis.” Stroke 42, no. 11 (November 2011): 3017–21. https://doi.org/10.1161/STROKEAHA.111.625186.Full Text Link to Item
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Rocha-Singh, Krishna J., Victor Novack, Michael Pencina, Ralph D’Agostino, Gary Ansel, Kenneth Rosenfield, and Michael R. Jaff. “Objective performance goals of safety and blood pressure efficacy for clinical trials of renal artery bare metal stents in hypertensive patients with atherosclerotic renal artery stenosis.” Catheter Cardiovasc Interv 78, no. 5 (November 1, 2011): 779–89. https://doi.org/10.1002/ccd.23055.Full Text Link to Item
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Polak, J. F., M. J. Pencina, and R. B. D’Agostino. “The authors reply.” New England Journal of Medicine 365, no. 17 (October 27, 2011): 1641–42.
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Polak, Joseph F., Michael J. Pencina, and Ralph B. D’Agostino. “Carotid Intima-Media Thickness and Cardiovascular Events REPLY.” New England Journal of Medicine 365, no. 17 (October 27, 2011): 1641–42.Link to Item
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Bangalore, Sripal, David J. Cohen, Neal S. Kleiman, Tal Regev-Beinart, Sunil V. Rao, Michael J. Pencina, Laura Mauri, and Laura EVENT Registry Investigators, Boston, MA. “Bleeding risk comparing targeted low-dose heparin with bivalirudin in patients undergoing percutaneous coronary intervention: results from a propensity score-matched analysis of the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry.” Circ Cardiovasc Interv 4, no. 5 (October 1, 2011): 463–73. https://doi.org/10.1161/CIRCINTERVENTIONS.111.961912.Full Text Link to Item
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Lindsey, Jason B., Kevin F. Kennedy, Joshua M. Stolker, Ian C. Gilchrist, Debabrata Mukherjee, Steven P. Marso, Michael J. Pencina, Neal S. Kleiman, and David J. Cohen. “Prognostic implications of creatine kinase-MB elevation after percutaneous coronary intervention: results from the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry.” Circ Cardiovasc Interv 4, no. 5 (October 1, 2011): 474–80. https://doi.org/10.1161/CIRCINTERVENTIONS.111.962233.Full Text Link to Item
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Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.” Eur J Clin Invest 41, no. 9 (September 2011): 1010–35. https://doi.org/10.1111/j.1365-2362.2011.02493.x.Full Text Link to Item
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Steyerberg, Ewout W., Ben Van Calster, and Michael J. Pencina. “[Performance measures for prediction models and markers: evaluation of predictions and classifications].” Rev Esp Cardiol 64, no. 9 (September 2011): 788–94. https://doi.org/10.1016/j.recesp.2011.04.017.Full Text Link to Item
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Venkitachalam, Lakshmi, Yang Lei, Joshua M. Stolker, Elizabeth M. Mahoney, Amit P. Amin, Jason B. Lindsey, Kevin F. Kennedy, et al. “Clinical and economic outcomes of liberal versus selective drug-eluting stent use: insights from temporal analysis of the multicenter Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry.” Circulation 124, no. 9 (August 30, 2011): 1028–37. https://doi.org/10.1161/CIRCULATIONAHA.110.978593.Full Text Link to Item
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Bhasin, Shalender, Michael Pencina, Guneet Kaur Jasuja, Thomas G. Travison, Andrea Coviello, Eric Orwoll, Patty Y. Wang, et al. “Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts.” J Clin Endocrinol Metab 96, no. 8 (August 2011): 2430–39. https://doi.org/10.1210/jc.2010-3012.Full Text Link to Item
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Lieb, Wolfgang, Michael J. Pencina, Paul F. Jacques, Thomas J. Wang, Martin G. Larson, Daniel Levy, William B. Kannel, and Ramachandran S. Vasan. “Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community.” Eur J Cardiovasc Prev Rehabil 18, no. 4 (August 2011): 664–73. https://doi.org/10.1177/1741826710389406.Full Text Link to Item
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Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration.” J Clin Epidemiol 64, no. 8 (August 2011): e1–22. https://doi.org/10.1016/j.jclinepi.2011.02.003.Full Text Link to Item
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Polak, Joseph F., Michael J. Pencina, Karol M. Pencina, Christopher J. O’Donnell, Philip A. Wolf, and Ralph B. D’Agostino. “Carotid-wall intima-media thickness and cardiovascular events.” N Engl J Med 365, no. 3 (July 21, 2011): 213–21. https://doi.org/10.1056/NEJMoa1012592.Full Text Link to Item
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Polak, Joseph F., Michael J. Pencina, David Herrington, and Daniel H. O’Leary. “Associations of edge-detected and manual-traced common carotid intima-media thickness measurements with Framingham risk factors: the multi-ethnic study of atherosclerosis.” Stroke 42, no. 7 (July 2011): 1912–16. https://doi.org/10.1161/STROKEAHA.110.603449.Full Text Link to Item
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Amin, Amit P., Kevin F. Kennedy, Michael Pencina, Peter Berger, Robert N. Piana, John Lopez, Neal Kleiman, David J. Cohen, and David J. EVENT Investigators. “Effect of clopidogrel pretreatment on ischemic complications of percutaneous coronary intervention among bivalirudin-treated patients (from the EVENT registry).” Am J Cardiol 107, no. 12 (June 15, 2011): 1751–56. https://doi.org/10.1016/j.amjcard.2011.02.331.Full Text Link to Item
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Murphy, Timothy P., Rajoo Dhangana, Michael J. Pencina, Abdul M. Zafar, and Ralph B. D’Agostino. “Performance of current guidelines for coronary heart disease prevention: optimal use of the Framingham-based risk assessment.” Atherosclerosis 216, no. 2 (June 2011): 452–57. https://doi.org/10.1016/j.atherosclerosis.2011.02.020.Full Text Link to Item
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Demler, Olga V., Michael J. Pencina, and Ralph B. D’Agostino. “Equivalence of improvement in area under ROC curve and linear discriminant analysis coefficient under assumption of normality.” Stat Med 30, no. 12 (May 30, 2011): 1410–18. https://doi.org/10.1002/sim.4196.Full Text Link to Item
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Uno, Hajime, Tianxi Cai, Michael J. Pencina, Ralph B. D’Agostino, and L. J. Wei. “On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data.” Stat Med 30, no. 10 (May 10, 2011): 1105–17. https://doi.org/10.1002/sim.4154.Full Text Link to Item
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Dhangana, Rajoo, Timothy P. Murphy, Michael J. Pencina, and Abdul M. Zafar. “Prevalence of low ankle-brachial index, elevated plasma fibrinogen and CRP across Framingham risk categories: data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004.” Atherosclerosis 216, no. 1 (May 2011): 174–79. https://doi.org/10.1016/j.atherosclerosis.2010.10.021.Full Text Link to Item
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Janssens, A. C. J. W., J. P. A. Ioannidis, S. Bedrosian, P. Boffetta, S. M. Dolan, N. Dowling, I. Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.” European Journal of Human Genetics : Ejhg 19, no. 5 (May 1, 2011).
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Zachariah, Justin P., Michael J. Pencina, Asya Lyass, Guneet Kaur, Ralph B. D’Agostino, Jose M. Ordovas, and Ramachandran S. Vasan. “Circulating plasma cholesteryl ester transfer protein activity and blood pressure tracking in the community.” J Hypertens 29, no. 5 (May 2011): 863–68. https://doi.org/10.1097/HJH.0b013e3283450223.Full Text Link to Item
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Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.” Eur J Hum Genet 19, no. 5 (May 2011): 18ppreceding494. https://doi.org/10.1038/ejhg.2011.27.Full Text Link to Item
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Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.” Eur J Epidemiol 26, no. 4 (April 2011): 313–37. https://doi.org/10.1007/s10654-011-9551-z.Full Text Link to Item
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Emerging Risk Factors Collaboration, John, David Wormser, Stephen Kaptoge, Emanuele Di Angelantonio, Angela M. Wood, Lisa Pennells, Alex Thompson, et al. “Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies.” Lancet 377, no. 9771 (March 26, 2011): 1085–95. https://doi.org/10.1016/S0140-6736(11)60105-0.Full Text Link to Item
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Brilakis, Emmanouil S., David J. Cohen, Neal S. Kleiman, Michael Pencina, Deborah Nassif, Jorge Saucedo, Robert N. Piana, et al. “Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry.” Am Heart J 161, no. 2 (February 2011): 360–66. https://doi.org/10.1016/j.ahj.2010.09.028.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Ewout W. Steyerberg. “Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers.” Stat Med 30, no. 1 (January 15, 2011): 11–21. https://doi.org/10.1002/sim.4085.Full Text Link to Item
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Menon, S., J. Massaro, J. Lewis, M. Pencina, Y. C. Wang, and P. Lavin. “Sample size calculation for poisson endpoint using the exact distribution of difference between two poisson random variables.” Statistics in Biopharmaceutical Research 3, no. 3 (January 1, 2011): 497–504. https://doi.org/10.1198/sbr.2011.10015.Full Text
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Dietrich, Marion, Paul F. Jacques, Joseph F. Polak, Michelle J. Keyes, Michael J. Pencina, Jane C. Evans, Philip A. Wolf, Jacob Selhub, Ramachandran S. Vasan, and Ralph B. D’Agostino. “Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study.” J Stroke Cerebrovasc Dis 20, no. 2 (2011): 155–61. https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.10.012.Full Text Link to Item
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Miguel-Yanes, Jose M. de, Peter Shrader, Michael J. Pencina, Caroline S. Fox, Alisa K. Manning, Richard W. Grant, Josèe Dupuis, et al. “Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.” Diabetes Care 34, no. 1 (January 2011): 121–25. https://doi.org/10.2337/dc10-1265.Full Text Link to Item
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Min, James K., Allison Dunning, Fay Y. Lin, Stephan Achenbach, Mouaz H. Al-Mallah, Daniel S. Berman, Matthew J. Budoff, et al. “Rationale and design of the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) Registry.” J Cardiovasc Comput Tomogr 5, no. 2 (2011): 84–92. https://doi.org/10.1016/j.jcct.2011.01.007.Full Text Link to Item
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Lam, Carolyn S. P., Xuan Liu, Qiong Yang, Martin G. Larson, Michael J. Pencina, Jayashri Aragam, Margaret M. Redfield, Emelia J. Benjamin, and Ramachandran S. Vasan. “Familial aggregation of left ventricular geometry and association with parental heart failure: the Framingham Heart Study.” Circ Cardiovasc Genet 3, no. 6 (December 2010): 492–98. https://doi.org/10.1161/CIRCGENETICS.110.941088.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Ramachandran S. Vasan. “Statistical methods for assessment of added usefulness of new biomarkers.” Clin Chem Lab Med 48, no. 12 (December 2010): 1703–11. https://doi.org/10.1515/CCLM.2010.340.Full Text Link to Item
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Mauri, Laura, Dean J. Kereiakes, Sharon-Lise T. Normand, Stephen D. Wiviott, David J. Cohen, David R. Holmes, Sripal Bangalore, Donald E. Cutlip, Michael Pencina, and Joseph M. Massaro. “Rationale and design of the dual antiplatelet therapy study, a prospective, multicenter, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy in subjects undergoing percutaneous coronary intervention with either drug-eluting stent or bare metal stent placement for the treatment of coronary artery lesions.” Am Heart J 160, no. 6 (December 2010): 1035-1041.e1. https://doi.org/10.1016/j.ahj.2010.07.038.Full Text Link to Item
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Polak, Joseph F., Michael J. Pencina, Allison Meisner, Karol M. Pencina, Lisa S. Brown, Philip A. Wolf, and Ralph B. D’Agostino. “Associations of carotid artery intima-media thickness (IMT) with risk factors and prevalent cardiovascular disease: comparison of mean common carotid artery IMT with maximum internal carotid artery IMT.” J Ultrasound Med 29, no. 12 (December 2010): 1759–68. https://doi.org/10.7863/jum.2010.29.12.1759.Full Text Link to Item
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Lubitz, Steven A., Xiaoyan Yin, João D. Fontes, Jared W. Magnani, Michiel Rienstra, Manju Pai, Mark L. Villalon, et al. “Association between familial atrial fibrillation and risk of new-onset atrial fibrillation.” Jama 304, no. 20 (November 24, 2010): 2263–69. https://doi.org/10.1001/jama.2010.1690.Full Text Link to Item
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Schnabel, Renate B., Thor Aspelund, Guo Li, Lisa M. Sullivan, Astrid Suchy-Dicey, Tamara B. Harris, Michael J. Pencina, et al. “Validation of an atrial fibrillation risk algorithm in whites and African Americans.” Arch Intern Med 170, no. 21 (November 22, 2010): 1909–17. https://doi.org/10.1001/archinternmed.2010.434.Full Text Link to Item
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Mitchell, G. F., S. J. Hwang, R. S. Vasan, M. G. Larson, D. Levy, E. J. Benjamin, M. J. Pencina, N. M. Hamburg, and J. A. Vita. “Response to letters regarding article, arterial stiffness and cardiovascular events: The framingham heart study.” Circulation 122, no. 19 (November 9, 2010). https://doi.org/10.1161/CIRCULATIONAHA.110.967141.Full Text
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Lopez, John J., Michelle J. Keyes, Sandeep Nathan, Robert Piana, Michael Pencina, Gaurav Dhar, Steven Marso, et al. “Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era.” Am Heart J 160, no. 4 (October 2010): 767–74. https://doi.org/10.1016/j.ahj.2010.06.048.Full Text Link to Item
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Thompson, Simon, Stephen Kaptoge, Ian White, Angela Wood, Philip Perry, John Danesh, and John Emerging Risk Factors Collaboration. “Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies.” Int J Epidemiol 39, no. 5 (October 2010): 1345–59. https://doi.org/10.1093/ije/dyq063.Full Text Link to Item
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Novack, Victor, Michael C. Nguyen, Meredith Rooney, Riya Chacko, Lena Novack, Michael Pencina, Patricia Apruzzese, et al. “Effect of coronary target lesion revascularization on late cardiac events after insertion of sirolimus-eluting or bare metal stents.” Am J Cardiol 106, no. 6 (September 15, 2010): 774–79. https://doi.org/10.1016/j.amjcard.2010.04.039.Full Text Link to Item
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Berger, Peter B., Neal S. Kleiman, Michael J. Pencina, Wen-Hua Hsieh, Steven R. Steinhubl, Allen Jeremias, Ali Sonel, et al. “Frequency of major noncardiac surgery and subsequent adverse events in the year after drug-eluting stent placement results from the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry.” Jacc Cardiovasc Interv 3, no. 9 (September 2010): 920–27. https://doi.org/10.1016/j.jcin.2010.03.021.Full Text Link to Item
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Novack, Victor, Michael Pencina, Doron Zahger, Lior Fuchs, Roman Nevzorov, Allan Jotkowitz, and Avi Porath. “Routine laboratory results and thirty day and one-year mortality risk following hospitalization with acute decompensated heart failure.” Plos One 5, no. 8 (August 17, 2010): e12184. https://doi.org/10.1371/journal.pone.0012184.Full Text Link to Item
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Vasan, R. S., M. J. Pencina, S. J. Robins, R. B. D’Agostino, G. Kaur, J. P. Zachariah, and J. M. Ordovas. “Response to letter regarding article, "association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community".” Circulation 122, no. 6 (August 10, 2010). https://doi.org/10.1161/CIRCULATIONAHA.110.951822.Full Text
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Stolker, Joshua M., Kevin F. Kennedy, Jason B. Lindsey, Steven P. Marso, Michael J. Pencina, Donald E. Cutlip, Laura Mauri, Neal S. Kleiman, David J. Cohen, and David J. EVENT Investigators. “Predicting restenosis of drug-eluting stents placed in real-world clinical practice: derivation and validation of a risk model from the EVENT registry.” Circ Cardiovasc Interv 3, no. 4 (August 2010): 327–34. https://doi.org/10.1161/CIRCINTERVENTIONS.110.946939.Full Text Link to Item
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Kimokoti, Ruth W., P. K. Newby, Philimon Gona, Lei Zhu, Guneet K. Jasuja, Michael J. Pencina, Catherine McKeon-O’Malley, Caroline S. Fox, Ralph B. D’Agostino, and Barbara E. Millen. “Diet quality, physical activity, smoking status, and weight fluctuation are associated with weight change in women and men.” J Nutr 140, no. 7 (July 2010): 1287–93. https://doi.org/10.3945/jn.109.120808.Full Text Link to Item
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Emerging Risk Factors Collaboration, J., N. Sarwar, P. Gao, SR Kondapally Seshasai, R. Gobin, S. Kaptoge, E. Di Angelantonio, et al. “Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.” Lancet 375, no. 9733 (June 26, 2010): 2215–22. https://doi.org/10.1016/S0140-6736(10)60484-9.Full Text Link to Item
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Krasnoff, Joanne B., Shehzad Basaria, Michael J. Pencina, Guneet K. Jasuja, Ramachandran S. Vasan, Jagadish Ulloor, Anqi Zhang, et al. “Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study.” J Clin Endocrinol Metab 95, no. 6 (June 2010): 2790–99. https://doi.org/10.1210/jc.2009-2680.Full Text Link to Item
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Howell, Michael D., Victor Novack, Philip Grgurich, Diane Soulliard, Lena Novack, Michael Pencina, and Daniel Talmor. “Iatrogenic gastric acid suppression and the risk of nosocomial Clostridium difficile infection.” Arch Intern Med 170, no. 9 (May 10, 2010): 784–90. https://doi.org/10.1001/archinternmed.2010.89.Full Text Link to Item
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Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, John, Nadeem Sarwar, Manjinder S. Sandhu, Sally L. Ricketts, Adam S. Butterworth, Emanuele Di Angelantonio, S Matthijs Boekholdt, et al. “Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.” Lancet 375, no. 9726 (May 8, 2010): 1634–39. https://doi.org/10.1016/S0140-6736(10)60545-4.Full Text Link to Item
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Velagaleti, Raghava S., Michael J. Pencina, Ramachandran S. Vasan, Emelia J. Benjamin, Joseph M. Massaro, Karol Pencina, and Daniel Levy. “Cross-sectional relations of lipid concentrations to left ventricular structural attributes.” Am J Cardiol 105, no. 9 (May 1, 2010): 1297–99. https://doi.org/10.1016/j.amjcard.2009.12.050.Full Text Link to Item
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Wolongevicz, Dolores M., Lei Zhu, Michael J. Pencina, Ruth W. Kimokoti, P. K. Newby, Ralph B. D’Agostino, and Barbara E. Millen. “Diet quality and obesity in women: the Framingham Nutrition Studies.” Br J Nutr 103, no. 8 (April 2010): 1223–29. https://doi.org/10.1017/S0007114509992893.Full Text Link to Item
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Mitchell, Gary F., Shih-Jen Hwang, Ramachandran S. Vasan, Martin G. Larson, Michael J. Pencina, Naomi M. Hamburg, Joseph A. Vita, Daniel Levy, and Emelia J. Benjamin. “Arterial stiffness and cardiovascular events: the Framingham Heart Study.” Circulation 121, no. 4 (February 2, 2010): 505–11. https://doi.org/10.1161/CIRCULATIONAHA.109.886655.Full Text Link to Item
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Steyerberg, Ewout W., and Michael J. Pencina. “Reclassification calculations for persons with incomplete follow-up.” Ann Intern Med 152, no. 3 (February 2, 2010): 195–96. https://doi.org/10.7326/0003-4819-152-3-201002020-00019.Full Text Link to Item
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Dasta, Joseph F., Sandra L. Kane-Gill, Michael Pencina, Yahya Shehabi, Paula M. Bokesch, Wayne Wisemandle, and Richard R. Riker. “A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit.” Crit Care Med 38, no. 2 (February 2010): 497–503. https://doi.org/10.1097/CCM.0b013e3181bc81c9.Full Text Link to Item
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Romanens, Michel, Franz Ackermann, John David Spence, Roger Darioli, Nicolas Rodondi, Roberto Corti, Georg Noll, Matthias Schwenkglenks, and Michael Pencina. “Improvement of cardiovascular risk prediction: time to review current knowledge, debates, and fundamentals on how to assess test characteristics.” Eur J Cardiovasc Prev Rehabil 17, no. 1 (February 2010): 18–23. https://doi.org/10.1097/HJR.0b013e3283347059.Full Text Link to Item
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Schnabel, Renate B., Martin G. Larson, Jennifer F. Yamamoto, Lisa M. Sullivan, Michael J. Pencina, James B. Meigs, Geoffrey H. Tofler, et al. “Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community.” Circulation 121, no. 2 (January 19, 2010): 200–207. https://doi.org/10.1161/CIRCULATIONAHA.109.882241.Full Text Link to Item
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Sofat, Reecha, Aroon D. Hingorani, Liam Smeeth, Steve E. Humphries, Philippa J. Talmud, Jackie Cooper, Tina Shah, et al. “Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.” Circulation 121, no. 1 (January 5, 2010): 52–62. https://doi.org/10.1161/CIRCULATIONAHA.109.865444.Full Text Link to Item
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Wolongevicz, Dolores M., Lei Zhu, Michael J. Pencina, Ruth W. Kimokoti, P. K. Newby, Ralph B. D’Agostino, and Barbara E. Millen. “An obesity dietary quality index predicts abdominal obesity in women: potential opportunity for new prevention and treatment paradigms.” J Obes 2010 (2010). https://doi.org/10.1155/2010/945987.Full Text Link to Item
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Steyerberg, Ewout W., Andrew J. Vickers, Nancy R. Cook, Thomas Gerds, Mithat Gonen, Nancy Obuchowski, Michael J. Pencina, and Michael W. Kattan. “Assessing the performance of prediction models: a framework for traditional and novel measures.” Epidemiology 21, no. 1 (January 2010): 128–38. https://doi.org/10.1097/EDE.0b013e3181c30fb2.Full Text Link to Item
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Vasan, Ramachandran S., Michael J. Pencina, Sander J. Robins, Justin P. Zachariah, Guneet Kaur, Ralph B. D’Agostino, and Jose M. Ordovas. “Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community.” Circulation 120, no. 24 (December 15, 2009): 2414–20. https://doi.org/10.1161/CIRCULATIONAHA.109.872705.Full Text Link to Item
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Emerging Risk Factors Collaboration, John, Emanuele Di Angelantonio, Nadeem Sarwar, Philip Perry, Stephen Kaptoge, Kausik K. Ray, Alexander Thompson, et al. “Major lipids, apolipoproteins, and risk of vascular disease.” Jama 302, no. 18 (November 11, 2009): 1993–2000. https://doi.org/10.1001/jama.2009.1619.Full Text Link to Item
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Lindsey, Jason B., Steven P. Marso, Michael Pencina, Joshua M. Stolker, Kevin F. Kennedy, Charanjit Rihal, Greg Barsness, et al. “Prognostic impact of periprocedural bleeding and myocardial infarction after percutaneous coronary intervention in unselected patients: results from the EVENT (evaluation of drug-eluting stents and ischemic events) registry.” Jacc Cardiovasc Interv 2, no. 11 (November 2009): 1074–82. https://doi.org/10.1016/j.jcin.2009.09.002.Full Text Link to Item
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Matthan, Nirupa R., Michael Pencina, Jane M. LaRocque, Paul F. Jacques, Ralph B. D’Agostino, Ernst J. Schaefer, and Alice H. Lichtenstein. “Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD.” J Lipid Res 50, no. 9 (September 2009): 1927–35. https://doi.org/10.1194/jlr.P900039-JLR200.Full Text Link to Item
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Dietrich, M., P. F. Jacques, M. J. Pencina, K. Lanier, M. J. Keyes, G. Kaur, P. A. Wolf, R. B. D’Agostino, and R. S. Vasan. “Vitamin E supplement use and the incidence of cardiovascular disease and all-cause mortality in the Framingham Heart Study: Does the underlying health status play a role?” Atherosclerosis 205, no. 2 (August 2009): 549–53. https://doi.org/10.1016/j.atherosclerosis.2008.12.019.Full Text Link to Item
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Novack, Victor, Donald Cutlip, Neal Kleiman, Michael Pencina, Laura Mauri, Chen-Hsing Yen, Peter Berger, et al. “In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry.” Jacc Cardiovasc Interv 2, no. 8 (August 2009): 767–75. https://doi.org/10.1016/j.jcin.2009.05.016.Full Text Link to Item
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Emerging Risk Factors Collaboration, John, Sebhat Erqou, Stephen Kaptoge, Philip L. Perry, Emanuele Di Angelantonio, Alexander Thompson, Ian R. White, et al. “Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.” Jama 302, no. 4 (July 22, 2009): 412–23. https://doi.org/10.1001/jama.2009.1063.Full Text Link to Item
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Preis, Sarah Rosner, Michael J. Pencina, Shih-Jen Hwang, Ralph B. D’Agostino, Peter J. Savage, Daniel Levy, and Caroline S. Fox. “Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study.” Circulation 120, no. 3 (July 21, 2009): 212–20. https://doi.org/10.1161/CIRCULATIONAHA.108.846519.Full Text Link to Item
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Melander, Olle, Christopher Newton-Cheh, Peter Almgren, Bo Hedblad, Göran Berglund, Gunnar Engström, Margaretha Persson, et al. “Novel and conventional biomarkers for prediction of incident cardiovascular events in the community.” Jama 302, no. 1 (July 1, 2009): 49–57. https://doi.org/10.1001/jama.2009.943.Full Text Link to Item
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Lieb, Wolfgang, Vanessa Xanthakis, Lisa M. Sullivan, Jayashri Aragam, Michael J. Pencina, Martin G. Larson, Emelia J. Benjamin, and Ramachandran S. Vasan. “Longitudinal tracking of left ventricular mass over the adult life course: clinical correlates of short- and long-term change in the framingham offspring study.” Circulation 119, no. 24 (June 23, 2009): 3085–92. https://doi.org/10.1161/CIRCULATIONAHA.108.824243.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, Martin G. Larson, Joseph M. Massaro, and Ramachandran S. Vasan. “Predicting the 30-year risk of cardiovascular disease: the framingham heart study.” Circulation 119, no. 24 (June 23, 2009): 3078–84. https://doi.org/10.1161/CIRCULATIONAHA.108.816694.Full Text Link to Item
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Joseph, Jacob, Michael J. Pencina, Thomas J. Wang, Laura Hayes, Geoffrey H. Tofler, Paul Jacques, Jacob Selhub, et al. “Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community.” J Hypertens 27, no. 6 (June 2009): 1317–24. https://doi.org/10.1097/HJH.0b013e328329fc20.Full Text Link to Item
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Novack, Victor, Daniel Tsyvine, David J. Cohen, Michael Pencina, Joseph Dubin, Hossein Dehghani, Neal S. Kleiman, and Donald E. Cutlip. “Multivessel drug-eluting stenting and impact of diabetes mellitus--a report from the EVENT registry.” Catheter Cardiovasc Interv 73, no. 7 (June 1, 2009): 874–80. https://doi.org/10.1002/ccd.21925.Full Text Link to Item
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Jacobs, Karen, Peter Johnson, Jack Dennerlein, Denise Peterson, Justin Kaufman, Joshua Gold, Sarah Williams, et al. “University students' notebook computer use.” Appl Ergon 40, no. 3 (May 2009): 404–9. https://doi.org/10.1016/j.apergo.2008.11.009.Full Text Link to Item
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Preis, Sarah Rosner, Shih-Jen Hwang, Sean Coady, Michael J. Pencina, Ralph B. D’Agostino, Peter J. Savage, Daniel Levy, and Caroline S. Fox. “Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005.” Circulation 119, no. 13 (April 7, 2009): 1728–35. https://doi.org/10.1161/CIRCULATIONAHA.108.829176.Full Text Link to Item
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Dhingra, Ravi, Michael J. Pencina, Peter Schrader, Thomas J. Wang, Daniel Levy, Karol Pencina, Deborah A. Siwik, Wilson S. Colucci, Emelia J. Benjamin, and Ramachandran S. Vasan. “Relations of matrix remodeling biomarkers to blood pressure progression and incidence of hypertension in the community.” Circulation 119, no. 8 (March 3, 2009): 1101–7. https://doi.org/10.1161/CIRCULATIONAHA.108.821769.Full Text Link to Item
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Diaz, Tulio, Michael J. Pencina, Emelia J. Benjamin, Jayashri Aragam, Deborah L. Fuller, Karol M. Pencina, Daniel Levy, and Ramachandran S. Vasan. “Prevalence, clinical correlates, and prognosis of discrete upper septal thickening on echocardiography: the Framingham Heart Study.” Echocardiography 26, no. 3 (March 2009): 247–53. https://doi.org/10.1111/j.1540-8175.2008.00806.x.Full Text Link to Item
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Schnabel, Renate B., Lisa M. Sullivan, Daniel Levy, Michael J. Pencina, Joseph M. Massaro, Ralph B. D’Agostino, Christopher Newton-Cheh, et al. “Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study.” Lancet 373, no. 9665 (February 28, 2009): 739–45. https://doi.org/10.1016/S0140-6736(09)60443-8.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, and Ramachandran S. Vasan. “Response to ‘Net reclassification improvement and decision theory’ by Vickers et al .” Statistics in Medicine 28, no. 3 (February 10, 2009): 526–28. https://doi.org/10.1002/sim.3475.Full Text
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Fernandez, Antonio B., Michelle J. Keyes, Michael Pencina, Ralph D’Agostino, Christopher J. O’Donnell, and Paul D. Thompson. “Relation of corneal arcus to cardiovascular disease (from the Framingham Heart Study data set).” Am J Cardiol 103, no. 1 (January 1, 2009): 64–66. https://doi.org/10.1016/j.amjcard.2008.08.030.Full Text Link to Item
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Latif, Faisal, Neal S. Kleiman, David J. Cohen, Michael J. Pencina, Chen-Hsing Yen, Donald E. Cutlip, David J. Moliterno, et al. “In-hospital and 1-year outcomes among percutaneous coronary intervention patients with chronic kidney disease in the era of drug-eluting stents: a report from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry.” Jacc Cardiovasc Interv 2, no. 1 (January 2009): 37–45. https://doi.org/10.1016/j.jcin.2008.06.012.Full Text Link to Item
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Lieb, Wolfgang, Michael J. Pencina, Katherine J. Lanier, Geoffrey H. Tofler, Daniel Levy, Caroline S. Fox, Thomas J. Wang, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study.” Diabetes 58, no. 1 (January 2009): 134–37. https://doi.org/10.2337/db08-0918.Full Text
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Velagaleti, Raghava S., Michael J. Pencina, Joanne M. Murabito, Thomas J. Wang, Nisha I. Parikh, Ralph B. D’Agostino, Daniel Levy, William B. Kannel, and Ramachandran S. Vasan. “Long-term trends in the incidence of heart failure after myocardial infarction.” Circulation 118, no. 20 (November 11, 2008): 2057–62. https://doi.org/10.1161/CIRCULATIONAHA.108.784215.Full Text Link to Item
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Lago, Rodrigo M., Michael J. Pencina, Thomas J. Wang, Katherine J. Lanier, Ralph B. D’Agostino, William B. Kannel, and Ramachandran S. Vasan. “Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study.” J Hypertens 26, no. 11 (November 2008): 2121–25. https://doi.org/10.1097/HJH.0b013e32830fe4a5.Full Text Link to Item
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Wilson, Peter W. F., Michael Pencina, Paul Jacques, Jacob Selhub, Ralph D’Agostino, and Christopher J. O’Donnell. “C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study.” Circ Cardiovasc Qual Outcomes 1, no. 2 (November 2008): 92–97. https://doi.org/10.1161/CIRCOUTCOMES.108.831198.Full Text Link to Item
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Fox, C. S., M. J. Pencina, and R. S. Vasan. “Obesity and hypothyroidism: Symbiotic coexistence - In reply.” Archives of Internal Medicine 168, no. 19 (October 27, 2008): 2168. https://doi.org/10.1001/archinte.168.19.2168-b.Full Text
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CAMMS223 Trial Investigators, P. K., Alasdair J. Coles, D Alastair S. Compston, Krzysztof W. Selmaj, Stephen L. Lake, Susan Moran, David H. Margolin, Kim Norris, and P. K. Tandon. “Alemtuzumab vs. interferon beta-1a in early multiple sclerosis.” N Engl J Med 359, no. 17 (October 23, 2008): 1786–1801. https://doi.org/10.1056/NEJMoa0802670.Full Text Link to Item
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Ingelsson, Erik, Michael J. Pencina, Daniel Levy, Jayashri Aragam, Gary F. Mitchell, Emelia J. Benjamin, and Ramachandran S. Vasan. “Aortic root diameter and longitudinal blood pressure tracking.” Hypertension 52, no. 3 (September 2008): 473–77. https://doi.org/10.1161/HYPERTENSIONAHA.108.114157.Full Text Link to Item
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McCarthy, Ellen P., Michael J. Pencina, Margaret Kelly-Hayes, Jane C. Evans, Elizabeth J. Oberacker, Ralph B. D’Agostino, Risa B. Burns, and Joanne M. Murabito. “Advance care planning and health care preferences of community-dwelling elders: the Framingham Heart Study.” J Gerontol a Biol Sci Med Sci 63, no. 9 (September 2008): 951–59. https://doi.org/10.1093/gerona/63.9.951.Full Text Link to Item
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Pencina, Michael J., Barbara E. Millen, Laura J. Hayes, and Ralph B. D’Agostino. “Performance of a method for identifying the unique dietary patterns of adult women and men: the Framingham nutrition studies.” J Am Diet Assoc 108, no. 9 (September 2008): 1453–60. https://doi.org/10.1016/j.jada.2008.06.442.Full Text Link to Item
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Jeremias, Allen, Neal S. Kleiman, Deborah Nassif, Wen-Hua Hsieh, Michael Pencina, Kelly Maresh, Manish Parikh, et al. “Prevalence and prognostic significance of preprocedural cardiac troponin elevation among patients with stable coronary artery disease undergoing percutaneous coronary intervention: results from the evaluation of drug eluting stents and ischemic events registry.” Circulation 118, no. 6 (August 5, 2008): 632–38. https://doi.org/10.1161/CIRCULATIONAHA.107.752428.Full Text Link to Item
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Lieb, Wolfgang, Michael J. Pencina, Thomas J. Wang, Martin G. Larson, Katherine J. Lanier, Emelia J. Benjamin, Daniel Levy, et al. “Association of parental hypertension with concentrations of select biomarkers in nonhypertensive offspring.” Hypertension 52, no. 2 (August 2008): 381–86. https://doi.org/10.1161/HYPERTENSIONAHA.108.113589.Full Text Link to Item
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Fox, Caroline S., Michael J. Pencina, Peter W. F. Wilson, Nina P. Paynter, Ramachandran S. Vasan, and Ralph B. D’Agostino. “Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.” Diabetes Care 31, no. 8 (August 2008): 1582–84. https://doi.org/10.2337/dc08-0025.Full Text Link to Item
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Murabito, Joanne M., Michael J. Pencina, Lei Zhu, Margaret Kelly-Hayes, Peter Shrader, and Ralph B. D’Agostino. “Temporal trends in self-reported functional limitations and physical disability among the community-dwelling elderly population: the Framingham heart study.” Am J Public Health 98, no. 7 (July 2008): 1256–62. https://doi.org/10.2105/AJPH.2007.128132.Full Text Link to Item
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Pencina, Michael J., and Ralph B. D’Agostino. “Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort--invited commentary.” Arch Intern Med 168, no. 11 (June 9, 2008): 1216–18. https://doi.org/10.1001/archinte.168.11.1216.Full Text Link to Item
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Cooper, Christopher J., Steven T. Haller, William Colyer, Michael Steffes, Mark W. Burket, William J. Thomas, Robert Safian, et al. “Embolic protection and platelet inhibition during renal artery stenting.” Circulation 117, no. 21 (May 27, 2008): 2752–60. https://doi.org/10.1161/CIRCULATIONAHA.107.730259.Full Text Link to Item
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Fox, Caroline S., Michael J. Pencina, Ralph B. D’Agostino, Joanne M. Murabito, Ellen W. Seely, Elizabeth N. Pearce, and Ramachandran S. Vasan. “Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample.” Arch Intern Med 168, no. 6 (March 24, 2008): 587–92. https://doi.org/10.1001/archinte.168.6.587.Full Text Link to Item
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D’Agostino, Ralph B., Ramachandran S. Vasan, Michael J. Pencina, Philip A. Wolf, Mark Cobain, Joseph M. Massaro, and William B. Kannel. “General cardiovascular risk profile for use in primary care: the Framingham Heart Study.” Circulation 117, no. 6 (February 12, 2008): 743–53. https://doi.org/10.1161/CIRCULATIONAHA.107.699579.Full Text Link to Item
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Cobain, M. R., M. J. Pencina, R. B. D’Agostino, and R. S. Vasan. “The Reply.” American Journal of Medicine 121, no. 2 (February 1, 2008). https://doi.org/10.1016/j.amjmed.2007.10.010.Full Text
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Freiberg, Matthew S., Michael J. Pencina, Ralph B. D’Agostino, Katherine Lanier, Peter W. F. Wilson, and Ramachandran S. Vasan. “BMI vs. waist circumference for identifying vascular risk.” Obesity (Silver Spring) 16, no. 2 (February 2008): 463–69. https://doi.org/10.1038/oby.2007.75.Full Text Link to Item
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Pencina, M. J., R. B. D’Agostino, and R. S. Vasan. “Comments on 'Integrated discrimination and net reclassification improvements - Practical advice'.” Statistics in Medicine 27, no. 2 (January 30, 2008): 207–12. https://doi.org/10.1002/sim.3106.Full Text
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Pencina, Michael J., Ralph B. D’Agostino, and Ramachandran S. Vasan. “Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.” Stat Med 27, no. 2 (January 30, 2008): 157–72. https://doi.org/10.1002/sim.2929.Full Text Link to Item
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Wang, Thomas J., Michael J. Pencina, Sarah L. Booth, Paul F. Jacques, Erik Ingelsson, Katherine Lanier, Emelia J. Benjamin, Ralph B. D’Agostino, Myles Wolf, and Ramachandran S. Vasan. “Vitamin D deficiency and risk of cardiovascular disease.” Circulation 117, no. 4 (January 29, 2008): 503–11. https://doi.org/10.1161/CIRCULATIONAHA.107.706127.Full Text Link to Item
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Levitzky, Yamini S., Michael J. Pencina, Ralph B. D’Agostino, James B. Meigs, Joanne M. Murabito, Ramachandran S. Vasan, and Caroline S. Fox. “Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study.” J Am Coll Cardiol 51, no. 3 (January 22, 2008): 264–70. https://doi.org/10.1016/j.jacc.2007.09.038.Full Text Link to Item
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Parikh, Nisha I., Michael J. Pencina, Thomas J. Wang, Emelia J. Benjamin, Katherine J. Lanier, Daniel Levy, Ralph B. D’Agostino, William B. Kannel, and Ramachandran S. Vasan. “A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study.” Ann Intern Med 148, no. 2 (January 15, 2008): 102–10. https://doi.org/10.7326/0003-4819-148-2-200801150-00005.Full Text Link to Item
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Ingelsson, E., M. J. Pencina, R. B. D’Agostino, and R. S. Vasan. “Utility of different lipid measures to predict coronary heart disease: Reply [3].” Jama 299, no. 1 (January 2, 2008): 36.
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Cromwell, William C., James D. Otvos, Michelle J. Keyes, Michael J. Pencina, Lisa Sullivan, Ramachandran S. Vasan, Peter W. F. Wilson, and Ralph B. D’Agostino. “LDL Particle Number and Risk of Future Cardiovascular Disease in the Framingham Offspring Study - Implications for LDL Management.” J Clin Lipidol 1, no. 6 (December 2007): 583–92. https://doi.org/10.1016/j.jacl.2007.10.001.Full Text Link to Item
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Lunetta, Kathryn L., Ralph B. D’Agostino, David Karasik, Emelia J. Benjamin, Chao-Yu Guo, Raju Govindaraju, Douglas P. Kiel, et al. “Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.” Bmc Med Genet 8 Suppl 1, no. Suppl 1 (September 19, 2007): S13. https://doi.org/10.1186/1471-2350-8-S1-S13.Full Text Link to Item
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Ingelsson, Erik, Michael J. Pencina, Geoffrey H. Tofler, Emelia J. Benjamin, Katherine J. Lanier, Paul F. Jacques, Caroline S. Fox, et al. “Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.” Circulation 116, no. 9 (August 28, 2007): 984–92. https://doi.org/10.1161/CIRCULATIONAHA.107.708537.Full Text Link to Item
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Ingelsson, Erik, Ernst J. Schaefer, John H. Contois, Judith R. McNamara, Lisa Sullivan, Michelle J. Keyes, Michael J. Pencina, et al. “Clinical utility of different lipid measures for prediction of coronary heart disease in men and women.” Jama 298, no. 7 (August 15, 2007): 776–85. https://doi.org/10.1001/jama.298.7.776.Full Text Link to Item
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Pencina, Michael J., Ramachandran S. Vasan, and Ralph B. D’Agostino. “Algorithms for assessing cardiovascular risk in women.” Jama 298, no. 2 (July 11, 2007): 175–76. https://doi.org/10.1001/jama.298.2.175.Full Text Link to Item
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Cobain, Mark R., Michael J. Pencina, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Lifetime risk for developing dyslipidemia: the Framingham Offspring Study.” Am J Med 120, no. 7 (July 2007): 623–30. https://doi.org/10.1016/j.amjmed.2006.12.015.Full Text Link to Item
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Clark, Uraina S., Marlene Oscar-Berman, Barbara Shagrin, and Michael Pencina. “Alcoholism and judgments of affective stimuli.” Neuropsychology 21, no. 3 (May 2007): 346–62. https://doi.org/10.1037/0894-4105.21.3.346.Full Text Link to Item
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Fox, Caroline S., Sean Coady, Paul D. Sorlie, Ralph B. D’Agostino, Michael J. Pencina, Ramachandran S. Vasan, James B. Meigs, Daniel Levy, and Peter J. Savage. “Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study.” Circulation 115, no. 12 (March 27, 2007): 1544–50. https://doi.org/10.1161/CIRCULATIONAHA.106.658948.Full Text Link to Item
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Steg, Ph Gabriel, Deepak L. Bhatt, Peter W. F. Wilson, Ralph D’Agostino, E Magnus Ohman, Joachim Röther, Chiau-Suong Liau, et al. “One-year cardiovascular event rates in outpatients with atherothrombosis.” Jama 297, no. 11 (March 21, 2007): 1197–1206. https://doi.org/10.1001/jama.297.11.1197.Full Text Link to Item
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Pencina, Michael J., Martin G. Larson, and Ralph B. D’Agostino. “Choice of time scale and its effect on significance of predictors in longitudinal studies.” Stat Med 26, no. 6 (March 15, 2007): 1343–59. https://doi.org/10.1002/sim.2699.Full Text Link to Item
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Terry, Dellara F., Jane C. Evans, Michael J. Pencina, Joanne M. Murabito, Ramachandran S. Vasan, Philip A. Wolf, Margaret Kelly-Hayes, Daniel Levy, Ralph B. D’Agostino, and Emelia J. Benjamin. “Characteristics of Framingham offspring participants with long-lived parents.” Arch Intern Med 167, no. 5 (March 12, 2007): 438–44. https://doi.org/10.1001/archinte.167.5.438.Full Text Link to Item
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Parikh, Nisha I., Michael J. Pencina, Thomas J. Wang, Katherine J. Lanier, Caroline S. Fox, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Increasing trends in incidence of overweight and obesity over 5 decades.” Am J Med 120, no. 3 (March 2007): 242–50. https://doi.org/10.1016/j.amjmed.2006.06.004.Full Text Link to Item
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Pencina, Michael J., Ralph B. D’Agostino, Alexa S. Beiser, Mark R. Cobain, and Ramachandran S. Vasan. “Estimating lifetime risk of developing high serum total cholesterol: adjustment for baseline prevalence and single-occasion measurements.” Am J Epidemiol 165, no. 4 (February 15, 2007): 464–72. https://doi.org/10.1093/aje/kwk025.Full Text Link to Item
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Emerging Risk Factors Collaboration, A. M., J. Danesh, S. Erqou, M. Walker, S. G. Thompson, R. Tipping, C. Ford, et al. “The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases.” Eur J Epidemiol 22, no. 12 (2007): 839–69. https://doi.org/10.1007/s10654-007-9165-7.Full Text Link to Item
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Arnlöv, Johan, Michael J. Pencina, Shreyasee Amin, Byung-Ho Nam, Emelia J. Benjamin, Joanne M. Murabito, Thomas J. Wang, et al. “Endogenous sex hormones and cardiovascular disease incidence in men.” Ann Intern Med 145, no. 3 (August 1, 2006): 176–84. https://doi.org/10.7326/0003-4819-145-3-200608010-00005.Full Text Link to Item
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Millen, Barbara E., Michael J. Pencina, Ruth W. Kimokoti, Lei Zhu, James B. Meigs, Jose M. Ordovas, and Ralph B. D’Agostino. “Nutritional risk and the metabolic syndrome in women: opportunities for preventive intervention from the Framingham Nutrition Study.” Am J Clin Nutr 84, no. 2 (August 2006): 434–41. https://doi.org/10.1093/ajcn/84.1.434.Full Text Link to Item
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Quatromoni, Paula A., Michael Pencina, Mark R. Cobain, Paul F. Jacques, and Ralph B. D’Agostino. “Dietary quality predicts adult weight gain: findings from the Framingham Offspring Study.” Obesity (Silver Spring) 14, no. 8 (August 2006): 1383–91. https://doi.org/10.1038/oby.2006.157.Full Text Link to Item
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Lee, Douglas S., Michael J. Pencina, Emelia J. Benjamin, Thomas J. Wang, Daniel Levy, Christopher J. O’Donnell, Byung-Ho Nam, Martin G. Larson, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Association of parental heart failure with risk of heart failure in offspring.” N Engl J Med 355, no. 2 (July 13, 2006): 138–47. https://doi.org/10.1056/NEJMoa052948.Full Text Link to Item
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Fox, Caroline S., Michael J. Pencina, James B. Meigs, Ramachandran S. Vasan, Yamini S. Levitzky, and Ralph B. D’Agostino. “Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study.” Circulation 113, no. 25 (June 27, 2006): 2914–18. https://doi.org/10.1161/CIRCULATIONAHA.106.613828.Full Text Link to Item
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Wilson, P. W. F., M. Pencina, R. B. D’Agostino, and C. J. O’Donnell. “In reply [13].” Archives of Internal Medicine 166, no. 12 (June 26, 2006): 1328. https://doi.org/10.1001/archinte.166.12.1328.Full Text
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Dhingra, Ravi, Michael J. Pencina, Thomas J. Wang, Byung-Ho Nam, Emelia J. Benjamin, Daniel Levy, Martin G. Larson, William B. Kannel, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study.” Hypertension 47, no. 5 (May 2006): 861–67. https://doi.org/10.1161/01.HYP.0000217141.20163.23.Full Text Link to Item
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Murabito, Joanne M., Michael J. Pencina, Byung-Ho Nam, Ralph B. D’Agostino, Thomas J. Wang, Donald Lloyd-Jones, Peter W. F. Wilson, and Christopher J. O’Donnell. “Sibling cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults.” Jama 294, no. 24 (December 28, 2005): 3117–23. https://doi.org/10.1001/jama.294.24.3117.Full Text Link to Item
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Wilson, Peter W. F., Byung-Ho Nam, Michael Pencina, Ralph B. D’Agostino, Emelia J. Benjamin, and Christopher J. O’Donnell. “C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart Study.” Arch Intern Med 165, no. 21 (November 28, 2005): 2473–78. https://doi.org/10.1001/archinte.165.21.2473.Full Text Link to Item
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Terry, Dellara F., Michael J. Pencina, Ramachandran S. Vasan, Joanne M. Murabito, Philip A. Wolf, Margaret Kelly Hayes, Daniel Levy, Ralph B. D’Agostino, and Emelia J. Benjamin. “Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants.” J Am Geriatr Soc 53, no. 11 (November 2005): 1944–50. https://doi.org/10.1111/j.1532-5415.2005.00465.x.Full Text Link to Item
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Millen, Barbara E., Paula A. Quatromoni, Michael Pencina, Ruth Kimokoti, Byung-H O. Nam, Sonia Cobain, Waldemar Kozak, Danielle P. Appugliese, Jose Ordovas, and Ralph B. D’Agostino. “Unique dietary patterns and chronic disease risk profiles of adult men: the Framingham nutrition studies.” J Am Diet Assoc 105, no. 11 (November 2005): 1723–34. https://doi.org/10.1016/j.jada.2005.08.007.Full Text Link to Item
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Vasan, Ramachandran S., Michael J. Pencina, Mark Cobain, Matthew S. Freiberg, and Ralph B. D’Agostino. “Estimated risks for developing obesity in the Framingham Heart Study.” Ann Intern Med 143, no. 7 (October 4, 2005): 473–80. https://doi.org/10.7326/0003-4819-143-7-200510040-00005.Full Text Link to Item
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Arnlöv, Johan, Michael J. Pencina, Byung-Ho Nam, James B. Meigs, Caroline S. Fox, Daniel Levy, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Relations of insulin sensitivity to longitudinal blood pressure tracking: variations with baseline age, body mass index, and blood pressure.” Circulation 112, no. 12 (September 20, 2005): 1719–27. https://doi.org/10.1161/CIRCULATIONAHA.105.535039.Full Text Link to Item
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Millen, Barbara E., Paula A. Quatromoni, Byung-Ho Nam, Michael J. Pencina, Joseph F. Polak, Ruth W. Kimokoti, Jose M. Ordovas, and Ralph B. D’Agostino. “Compliance with expert population-based dietary guidelines and lower odds of carotid atherosclerosis in women: the Framingham Nutrition Studies.” Am J Clin Nutr 82, no. 1 (July 2005): 174–80. https://doi.org/10.1093/ajcn.82.1.174.Full Text Link to Item
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Sonnenberg, Lillian, Michael Pencina, Ruth Kimokoti, Paula Quatromoni, Byung-Ho Nam, Ralph D’Agostino, James B. Meigs, Jose Ordovas, Mark Cobain, and Barbara Millen. “Dietary patterns and the metabolic syndrome in obese and non-obese Framingham women.” Obes Res 13, no. 1 (January 2005): 153–62. https://doi.org/10.1038/oby.2005.20.Full Text Link to Item
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Dhingra, Ravi, Michael J. Pencina, Emelia J. Benjamin, Daniel Levy, Martin G. Larson, James B. Meigs, Nader Rifai, Ralph B. D’Agostino, and Ramachandran S. Vasan. “Cross-sectional relations of urinary sodium excretion to cardiac structure and hypertrophy. The Framingham Heart Study.” Am J Hypertens 17, no. 10 (October 2004): 891–96. https://doi.org/10.1016/j.amjhyper.2004.06.008.Full Text Link to Item
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Pencina, Michael J., and Ralph B. D’Agostino. “Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation.” Stat Med 23, no. 13 (July 15, 2004): 2109–23. https://doi.org/10.1002/sim.1802.Full Text Link to Item
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Conference Papers
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Chapfuwa, P., S. Assaad, S. Zeng, M. J. Pencina, L. Carin, and R. Henao. “Enabling counterfactual survival analysis with balanced representations.” In Acm Chil 2021 Proceedings of the 2021 Acm Conference on Health, Inference, and Learning, 133–45, 2021. https://doi.org/10.1145/3450439.3451875.Full Text
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Poon, Eric G., Charles P. Friedman, Philip R. O. Payne, Michael J. Pencina, and Kevin B. Johnson. “Informatics-Enabled Learning Health Systems: Strategies for Success from Four Academic Medical Centers.” In Amia. AMIA, 2019.
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Cardet, Juan Carlos, Paula J. Busse, Jennifer K. Carroll, Thomas B. Casale, Tamera Coyne-Beasley, Maureen Fagan, Victoria E. Forth, et al. “Adherence to Adding ICS to Rescue Therapy in a Pragmatic Trial with Adults with Asthma– a Pilot Study.” In Journal of Allergy and Clinical Immunology, 141:AB209–AB209. Elsevier BV, 2018. https://doi.org/10.1016/j.jaci.2017.12.662.Full Text
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Rusincovitch, Shelley A., Lisa Wruck, Ricardo Henao, Larisa Rodgers, Allison Dunning, Peter Merrill, Hillary Mulder, et al. “The Duke Health Data Science Internship Program: Integrating the Educational Mission into Real-World Research.” In Amia. AMIA, 2018.
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Rosenstock, Julio, Vlado Perkovic, John H. Alexander, Mark Emmanuel Cooper, Steven E. Kahn, Nikolaus Marx, Michael J. Pencina, et al. “CARMELINA (R) Trial Baseline Characteristics: A Cardiovascular and Renal Microvascular Outcome Trial with Linagliptin in Patients with Type 2 Diabetes at High Vascular Risk.” In Diabetes, 66:A344–A344. AMER DIABETES ASSOC, 2017.Link to Item
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Tasneem, Asba, Karen Chiswell, Brian J. McCourt, Matt Gross, Eric Peterson, and Michael J. Pencina. “Developing a framework for a comprehensive data sharing program.” In Amia. AMIA, 2017.
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Goldstein, Benjamin A., Ann Marie Navar, Michael J. Pencina, and John P. A. Ioannidis. “A Systematic Review of Using Electronic Heath Records to Predict Clinical Events: Assessment of Opportunities and Challenges.” In Cri. AMIA, 2016.
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Shelton, Richard C., Michael J. Pencina, Lori J. Barrentine, Juan A. Ruiz, George I. Papakostas, Zajecka M. Zajecka, and Maurizio Fava. “Association of Obesity and Levels of Inflammatory Markers on Treatment Outcome with Adjunctive (6S)-5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic Acid (CH3-FH4) in MDD Patients Who are Inadequate Responders to SSRIs.” In Biological Psychiatry, 77:131S-131S. ELSEVIER SCIENCE INC, 2015.Link to Item
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Greiner, Melissa A., Emily O’Brien, Ying Xian, Deepak L. Bhatt, Lesley Maisch, Deidre Hannah, Brianna Lindholm, et al. “High vs. Moderate-intensity Statin Therapy After Ischemic Stroke: Findings from PROSPER.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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O’Brien, Emily C., Melissa A. Greiner, Ying Xian, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Statin Therapy after Ischemic Stroke: Primary Results from the PROSPER Study.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Xian, Ying, Jingjing Wu, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Anticoagulation with Warfarin among Ischemic Stroke Patients with Atrial Fibrillation: Findings from the Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Navar-Boggan, Ann M., Eric D. Peterson, Ralph B. D’Agostino, Benjamin Neely, Allan D. Sniderman, and Michael J. Pencina. “Future Risk of Cardiovascular Disease in Adults with Prolonged Exposure to High Blood Pressure.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.Link to Item
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Navar-Boggan, Ann M., Tomasz Zdrojewski, Adam Wyszomirski, Mateusz Lachacz, Grzegorz Opolski, Piotr Bandosz, Marcin Rutkowski, Zbigniew Gaciong, Bogdan Wyrzykowski, and Michael J. Pencina. “European and American Blood Cholesterol Guidelines Result in Similar Rates of Statin Recommendations when Applied to a Country with High Cardiovascular Disease Risk.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.Link to Item
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Polak, Joseph F., Allison Meisner, Michael J. Pencina, Ramachandran S. Vasan, Philip A. Wolf, and Ralph B. D’Agostino. “Incident Congestive Heart Failure and Common Carotid Artery Diameter: The Framingham Offspring Study.” In Circulation, Vol. 124. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Polak, Joseph F., Michael J. Pencina, Allison Meisner, Philip A. Wolf, and Ralph B. D’Agostino. “Prevalent Cardiovascular Disease and Progression of Carotid Intima-Media Thickness.” In Circulation, Vol. 124. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Ho, Jennifer E., Douglas S. Lee, Philimon Gona, Michael J. Pencina, Ramachandran S. Vasan, William B. Kannel, Ralph B. D’Agostino, and Daniel Levy. “Clinical Predictors of Heart Failure with Preserved vs Reduced Ejection Fraction: Data from the Framingham Heart Study.” In Circulation, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Meisner, Allison, Michael J. Pencina, Ralph B. D’Agostino, Philip A. Wolf, and Joseph J. Polak. “Carotid Plaque Improves Discrimination and Reclassification of Cardiovascular Risk Prediction Models.” In Circulation, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Preis, Sarah R., Michael J. Pencina, Ralph B. D’Agostino, Peter J. Savage, and Caroline S. Fox. “Lifecourse Analysis Reveals Adverse Cardiovascular Disease Risk Factor Profiles up to 30 Years Prior to the Diagnosis of Diabetes.” In Circulation, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Zachariah, Justin P., Michael J. Pencina, Asya Lyass, Guneet Kaur, Ralph B. D’Agostino, Jose M. Ordovas, and Ramachandran S. Vasan. “Circulating Plasma CETP Activity and Blood Pressure Tracking in the Community.” In Hypertension, 56:E65–66. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Kimokoti, Ruth W., P. K. Newby, Guneet Kaur, Lei Zhu, Michael J. Pencina, Catherine McKeon-O’Malley, Caroline S. Fox, Ralph B. D’Agostino, and Barbara E. Millen. “Diet Quality, Lifestyle and Weight Change in Framingham Women and Men: The Framingham Nutrition Studies.” In Circulation, 120:S456–57. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Pencina, Michael J., and Ralph B. D’Agostino. “Education Independently Predicts Risk of Cardiovascular Disease but Only Modestly Improves Performance of Framingham Risk Functions.” In Circulation, 120:S410–S410. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Polak, Joseph F., Michael J. Pencina, Christopher J. O’Donnell, Philip A. Wolf, and Ralph D’Agostino. “Added Value of the Common and Internal Carotid Intima-media Thickness (IMT) for the Prediction of Cardiovascular Events: The Framingham Offspring Study.” In Circulation, 120:S425–S425. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Polak, Joseph F., Michael J. Pencina, Lei Zhu, Philip A. Wolf, and Ralph D’Agostino. “Carotid Artery Plaque is More Strongly Associated With Prior Cardiovascular Risk Factor Levels Than With Current Risk Factor Levels.” In Circulation, 120:S1157–S1157. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Preis, Sarah R., Michael J. Pencina, Ralph B. D’Agostino, Ramachandran S. Vasan, Daniel Levy, and Caroline S. Fox. “Neck Circumference and Development of Cardiovascular Disease Risk Factors in the Framingham Heart Study.” In Circulation, 120:S509–S509. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Prushik, Scott G., Alik Farber, Philimon Gona, Peter Shrader, Michael J. Pencina, Ralph B. D’Agostino, and Joanne M. Murabito. “Parental Occurrence of Intermittent Claudication is an Independent Risk Factor for Intermittent Claudication in Adult Offspring: The Framingham Heart Study.” In Circulation, 120:S431–S431. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Velagaleti, Raghava S., Michael J. Pencina, Jayashri Aragam, Thomas J. Wang, Daniel Levy, Ralph B. D’Agostino, William B. Kannel, Emelia J. Benjamin, and Ramachandran S. Vasan. “Left Ventricular Hypertrophy Patterns and the Incidence of Heart Failure: The Framingham Heart Study.” In Circulation, 120:S415–S415. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Kimokoti, Ruth W., P. K. Newby, Guneet Kaur, Lei Zhu, Michael J. Pencina, Ralph B. D’Agostino, and Barbara E. Millen. “The Effect of Diet Quality and Other Determinants on Weight Change in Framingham Women and Men:The Framingham Nutrition Studies.” In Obesity, 17:S311–S311. NATURE PUBLISHING GROUP, 2009.Link to Item
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Stolker, Joshua M., Jason B. Lindsey, Steven P. Marso, Kevin F. Kennedy, Michael J. Pencina, Donald E. Cutlip, Neal S. Kleiman, and David J. Cohen. “Derivation and Validation of a Risk Model for Predicting Clinically-Driven Target Lesion Revascularization in Drug Eluting Stents.” In American Journal of Cardiology, 104:15D-15D. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2009.Link to Item
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Brown, Lisa S., Josepth F. Polak, Michael J. Pencina, Lei Zhu, Sarah M. Karl, Ruth W. Kimokoti, Ralph B. D’Agostino, and Barbara E. Millen. “Segment-Specific Associations of Carotid Artery Intima-Media Thickness with Dietary Fat Intake.” In Circulation, 119:E307–E307. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Lieb, Wolfgang, Vanessa Xanthakis, Lisa M. Sullivan, Jayashri Aragam, Michael J. Pencina, Martin G. Larson, Emelia J. Benjamin, and Ramachandran S. Vasan. “Tracking of Left Ventricular Mass over the Adult Life Course: Clinical Correlates in the Framingham Offspring Study.” In Circulation, 119:E278–79. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Stolker, Joshua M., Jason B. Lindsey, Steven P. Marso, Kevin F. Kennedy, Michael J. Pencina, Donald E. Cutlip, Neal S. Kleiman, and David J. Cohen. “Predictors of Clinical Restenosis in Real-World Clinical Practice: An Analysis of Drug Eluting Stents in the EVENT Multicenter Registry.” In Journal of the American College of Cardiology, 53:A38–A38. ELSEVIER SCIENCE INC, 2009.Link to Item
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Dhangana, Rajoo, Timothy P. Murphy, Michael J. Pencina, and Todd D. Durham. “Ankle-brachial Index And Fibrinogen Improve Cardiovascular Risk Prediction And Classification.” In Circulation, 118:S1156–S1156. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Polak, Joseph F., Michael J. Pencina, Karol M. Pencina, Lisa S. Brown, Philip A. Wolf, and Ralph B. D’Agostino. “Differences in Intima Media Thickness of the Common and Internal Carotid Arteries.” In Circulation, 118:S1096–S1096. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Preis, Sarah R., Michael J. Pencina, Shih-Jen Hwang, Ralph B. D’Agostino, Peter Savage, Daniel Levy, and Caroline S. Fox. “Trends in Cardiovascular Disease Risk Factors among Middle-Aged Individuals with and without Diabetes in the Framingham Heart Study.” In Circulation, 118:S1082–S1082. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Schnabel, Renate B., Lisa M. Sullivan, Daniel Levy, Michael J. Pencina, Joseph M. Massaro, Ralph B. D’Agostino, Christopher Newton-Cheh, et al. “Development of a Risk Score for Incident Atrial Fibrillation in the Community; the Framingham Heart Study.” In Circulation, 118:S1089–90. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Fox, Caroline S., Michael’ J. Pencina, Ramachandran S. Vasan, Larry D. Atwood, Christopher J. O’Donnell, and Ralph B. D’Agostino. “Parental history of obesity is a stronger risk factor for elevated body mass index in more contemporary time periods.” In Diabetes, 57:A280–A280. AMER DIABETES ASSOC, 2008.Link to Item
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Preis, Sarah R., Shih-Jen Hwang, Sean Coady, Ralph D’Agostino, Michael J. Pencina, Peter Savage, Daniel Levy, and Caroline S. Fox. “Trends in mortality among women and men with and without diabetes in the Framingham heart study - Abstracts.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Jeremias, Allen, Deborah Nassif, Wen-Hua Hsieh, Michael J. Pencina, Kelly Maresh, Manish A. Parikh, Donald E. Cutlip, Peter B. Berger, Neal S. Kleiman, and David J. Cohen. “Prevalence and prognostic significance of pre-procedure cardiac troponin elevation among patients with stable coronary artery disease undergoing percutaneous coronary intervention: Results from the EVENT registry.” In Journal of the American College of Cardiology, 51:A260–A260. ELSEVIER SCIENCE INC, 2008.Link to Item
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Brown, Lisa S., Joseph F. Polak, Michael J. Pencina, Ruth W. Kimokoti, Ralph B. D’Agostino, and Barbara E. Millen. “Dietary patterns and risk of increased carotid intima-media thickness in women: The framingham nutrition studies.” In Circulation, 116:827–28. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Palaniappan, Latha P., Michael J. Pencina, Ramachandran S. Vasan, Meng Wang, Ralph B. D’Agostino, and Helena C. Kraemer. “Signal detection decision tree for risk stratification for cardiovascular disease in women.” In Circulation, 115:E562–E562. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Levitzky, Yamini S., Michael J. Pencina, Ralph B. D’Agostino, James B. Meigs, Joanne M. Murabito, Ramachandran S. Vasan, and Caroline S. Fox. “Impaired fasting glucose and cardiovascular disease: The Framingham heart study.” In Diabetes, 55:A1–A1. AMER DIABETES ASSOC, 2006.Link to Item
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- Teaching & Mentoring
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Advising & Mentoring
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- Benjamin A. Goldstein, PhD, who joined Duke from Stanford; nationally recognized leader in methods of analysis of electronic health records data
- Roland A. Matsouaka, PhD, post-doctoral graduate of Harvard who is developing methodologies for analysis of multiple outcome pragmatic trials
- Frank W. Rockhold, PhD, ScM, Fellow of the American Statistical Association who joined Duke after a successful career as Chief Safety Officer and Senior Vice President of Global Clinical Safety and Pharmacovigilance at GSK and is a world leader in Open Science and methods of analysis of clinical trials.
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Teaching Activities
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- Lecturer, Applied Statistical Methods, Goldman School of Dental Medicine, Boston University, 2002
- Co-Lecturer, Advanced Statistical Methods, College of Arts and Sciences, Boston University, 2003 – 2010
- Faculty, Basic Statistics and Probability, College of Arts and Sciences, Boston University, 2003 – 2007
- Faculty, Statistics II, College of Arts and Sciences, Boston University, 2004 – 2006
- Faculty, Applied Statistics, College of Arts and Sciences, Boston University, 2007
- Faculty, Statistical Methods for Epidemiology, Boston University, 2009 – 2013
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- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- “Beyond the Black Box: Using Machine Learning (ML) to Understand Causality”. 2019 Scientific Sessions. American Heart Association. November 2019 2019
- “Informatics-Enabled Learning Health Systems: Strategies for Success from 4 Academic Medical Centers”. 2019 Annual Symposium. American Medical Informatics Association. November 2019 2019
- "AI Health and Data Session" Chair. 2019 Annual Meeting Woo Center for Big Data and Precision Health . Duke University. October 2019 2019
- "Getting the Most Out of Your Data". Community of Scholars Conference. Duke University Office of Scientist Development. October 2019 2019
- “Are We Losing Our Humanity? Health Care Leadership in the Age of Artificial Intelligence”. Duke Health Leadership Summit 2019. Duke University. March 2019 2019
- “Using Electronic Health Records Data for Risk Prediction: Practical Considerations” and “Machine Learning vs. Biostatistics: What is the Difference?”. 2018 Scientific Sessions. American Heart Association. November 2018 2018
- “Fusion of Quantitative Methods to Support Learning”. Precision Medicine World Conference 2018. Duke University. September 2018 2018
- Keynote Lecture: “Integrating the Role of Real-World Evidence (RWE) in Clinical Trials”. Corporate Forum Policy Dialogue. American Heart Association. August 2018 2018
- Keynote Lecture: "Moving from Big Data to Big Insights: Data Science as the Cornerstone of a Learning Health System”. Program on Statistical, Mathematical and Computational Methods for Precision Medicine. Statistical & Applied Mathematical Sciences Institute. August 2018 2018
- “An Equation-Free Presentation of New Methods for Prediction of Treatment Benefit and Model Evaluation”. Evidence and the Individual Patient: Understanding Heterogeneous Treatment Effects for Patient-Centered Care. Predictive Analytics & Comparative Effectiveness (PACE) Center at the Tufts Medical Center + Patient-Centered Outcomes Research Institute (PCORI). August 2018 2018
- “Moving from Big Data to Big Insights”. Biostatistics Seminar. Boston University School of Public Health. August 2018 2018
- "Data Science as a Cornerstone of a Learning Health System". The Data Science Conference. May 2018 2018
- “Evidence and the Individual Patient: Understanding Heterogeneous Treatment Effects (HTE) for Patient- Centered Care”. The National Academy of Medicine & Tufts Predictive Analytics Comparative Effectiveness Center. May 2018 2018
- "Machine Learning in Healthcare" Moderator. 2018 Health Datapalooza. Academy Health. April 2018 2018
- “Does Machine Learning Have a Place In a Learning Health System?”. NIH Collaboratory Grand Rounds. Duke Clinical Research Institute. December 2017 2017
- “Moving from Big Data to Big Insights”. 2017 Scientific Sessions. American Heart Association. November 2017 2017
- “How Can Prediction Models Help Tailor Individual and Population Care?”. 77th Scientific Sessions. American Diabetes Association. June 2017 2017
- Keynote, Richard D. Remington Methodology Lecture: "The Art and Science of Developing and Evaluating Risk Prediction Models”. 2016 Scientific Sessions. American Heart Association, Council on Epidemiology and Prevention. March 2016 2016
- “Neuroscience Trials of the Future – Statistical Considerations”. Institute of Medicine Workshop. U.S. National Academy of Sciences. March 2016 2016
- “Individual Trials versus Pooling Across Trials: A Preferred Approach for ‘Truth’ ”. 2015 Scientific Sessions. American Heart Association. November 2015 2015
- “New U.S. Lipid Guidelines: Main Advances and Open Questions”. Distinguished Professor Program Series. The Mazankowski Alberta Heart Institute, University of Alberta. June 2015 2015
- “Challenges of Surrogate Outcomes". 2014 Scientific Sessions. American Heart Association. November 2014 2014
- “Is There a Universe Beyond Sensitivity and Specificity in Evaluation of Diagnostic and Prognostic Performance?”. Joint Statistical Meeting Session. American Statistical Association. August 2014 2014
- “Discrimination and Reclassification”. 30th Beckman Conference, Statistics and Study Design Session. AACC/ASN. November 2013 2013
- “Interpreting Incremental Value of Biomarkers”. Vanderbilt University. November 2013 2013
- “How to Improve Assessment of Cardiovascular Risk”. Rene Robaire Memorial Lecture in Cardiovascular Research. McGill University. May 2013 2013
- “Assessment of Improvement in Model Performance and Value of New Markers”. Workshop on Risk Prediction. University of Cambridge. November 2012 2012
- “Interpreting Incremental Value of Risk Prediction Models”. University of Alabama. November 2012 2012
- “How to Improve Cardiovascular Disease Risk Assessment”. 2012 Annual Symposium. European Society of Cardiology. August 2012 2012
- Keynote Lecture: "Integrating Lifecourse Data into Risk Prediction Algorithms”. 2012 Netherlands Epidemiologic Conference. WEON, Dutch Society for Epidemiologic Research. June 2012 2012
- “How to Interpret Improvement in Risk Prediction Models”. Society for Epidemiologic Research. June 2012 2012
- “Improving Signal Detection in CNS Trials”. Investing and Partnering Conference. Neurotech. May 2012 2012
- "Discrimination and Reclassification". 2012 Scientific Sessions. American College of Cardiology. March 2012 2012
- "Risk Reclassification Workshop". Quality Control and Outcomes Research Conference. American Heart Association. March 2012 2012
- “How to Build and Interpret Risk Prediction Models”. Imaging Seminar Series. Brigham and Women's Hospital. February 2012 2012
- “Lifetime Risk of Dyslipidemia”. 1st Conference. Polish Lipid Association. September 2011 2011
- “Pioneering the Concept of Cardiovascular Risk to Modern Risk Function”. 10 Days of Hypertension & Diabetes. May 2011 2011
- “Novel Methods for Quantifying Improvement in Risk Prediction”. Biostatistics Seminar Series. Duke University. January 2011 2011
- “Statistical Techniques to Assess Novel Biomarkers: Beyond the ROC Curve”. 2010 Scientific Sessions. American Heart Association. November 2010 2010
- “Issues in Developing and Improving Risk Prediction Models”. Seminar Series. Hannover Medizinische HochSchule (Hannover Medical School). September 2010 2010
- “Development of Framingham Cardiovascular Risk Prediction Algorithms”. Workshop on Computational Cardiovascular and Cardiopulmonary Dynamics. National Heart, Lung, and Blood Institute + Virginia Commonwealth University. March 2009 2009
- “Issues in Development & Validation of Risk Prediction Models”. Joslin Diabetes Center. February 2009 2009
- “Quantifying Improvement in Risk Prediction Models”. Biostatistics Department Seminar Series. Harvard School of Public Health. February 2009 2009
- “Assessing Additional Value of New Biomarkers”. Genetic Risk Prediction Workshop. Harvard School of Public Health. November 2008 2008
- “Measuring the Accuracy of Prediction Models”. Quantitative Health Sciences International Symposium. Cleveland Clinic. September 2008 2008
- “Keynote Lecture, Bridging the Gaps: New Trends in Women’s Health”. Enhancing Partnerships to Improve Women’s Health Conference. March 2006 2006
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Service to the Profession
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Academic & Administrative Activities
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Reviewer for Medical and Statistical Journals:
- American Journal of Epidemiology
- Circulation
- Archives of Internal Medicine
- Journal of the American Dietetic Association
- Biometrics
- New England Journal of Medicine
- Biostatistics
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Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.