Michael J Pencina | Scholars@Duke

Michael J Pencina
Professor of Biostatistics & Bioinformatics

Current Appointments & Affiliations

Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2013
Vice Dean, Data Science and Information Technology, Biostatistics & Bioinformatics, Basic Science Departments 2018
Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2013

Contact Information

200 Trent Drive, M144 Davison Bldg, Durham, NC 27705
Duke Box 2927, Durham, NC 27710
(919) 613-9066

Background
Education, Training, & Certifications
- Ph.D., Boston University 2003
Leadership & Clinical Positions at Duke
- Vice Dean for Data Science and Information Technology
Recognition
In the News
- APR 19, 2017 Duke Health News
  
  Dueling Statin Guidelines Put 9 Million Americans at Crossroads
- NOV 13, 2016 Duke Health News
  
  Coronary Heart Disease Drops 20 Percent Since the 1980s
- JAN 27, 2015 TIME
  
  High cholesterol can be dangerous even if you're young
- JAN 27, 2015 The New York Times
  
  High cholesterol takes its toll over time
- JUN 24, 2014
  
  DCRI and Industry Collaboration Promotes Open Data Access
- MAR 20, 2014 USA Today
  
  Millions more would get statins based on new guidelines
- MAR 20, 2014
  
  New Guidelines Deem 13 Million More Americans Eligible for Statins
Awards & Honors
- Highly Cited Researcher. Thomson Reuters. 2014
Research
Selected Grants
- Addressing Bias from Missing Data in EHR Based Studies of CVD awarded by National Institutes of Health 2018 - 2023
- Financial and Social Behavioral Economic Incentives to Increase Physical Activity in Adolescents and Young Adults for Cardiovascular Health awarded by National Institutes of Health 2018 - 2023
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Preventing Cardiovascular Disease through Improved Risk Prediction and Communication awarded by National Institutes of Health 2016 - 2021
- Improved Disease Stratification Using Electronic Health Records awarded by National Institutes of Health 2017 - 2020
- ADAPTABLE awarded by Patient-Centered Outcomes Research Institute 2015 - 2020
- QuBBD: Deep Poisson Methods for Biomedical Time-to-Event and Longitudinal Data awarded by National Institutes of Health 2017 - 2020
- Predictive Analytic Treatment effect Heterogeneity (PATH) awarded by Tufts Medical Center 2018 - 2020
- A Personalized Metabolomic Approach to Human Obesity and Weight Loss awarded by National Institutes of Health 2016 - 2019
- Administrative Claims-based Efficiencies for the Advancement of Regulatory Sciences awarded by Burroughs Wellcome Fund 2014 - 2019
- PROSPER awarded by Patient-Centered Outcomes Research Institute 2013 - 2019
- PESRAMHIP awarded by Brigham and Women's Hospital 2016 - 2019
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2014 - 2019
- Risk prediction for S Arteriosclerotic Cardiovascular Disease (ASCVD) in persons on statins awarded by Regeneron Pharmaceuticals, Inc. 2016 - 2018
- Cardiovascular Risk Profile of LAL Deficiency Patients awarded by Alexion Pharmaceuticals, Inc. 2016 - 2018
- Risk Prediction for Secondary Events in Adults with Arteriosclerotic Cardiovascular Disease (ASCVD) awarded by Regeneron Pharmaceuticals, Inc. 2015 - 2018
- Duke CTSA (UL1): Statistical methods for complex data in CV disease research awarded by National Institutes of Health 2013 - 2018
- Modified KOR Phase 2A Study awarded by National Institutes of Health 2014 - 2017
- CKD Biomarkers Consortium awarded by University of Pennsylvania 2015 - 2017
- Assessment of the Number of Patients Treated for In-stent Restenosis using the Duke Health System awarded by Abbott Cardiovascular Systems, Inc. 2016 - 2017
- HIV and Asthma in the Post- ART Era awarded by National Institutes of Health 2014 - 2016
- FAST- MAS Administrative Task Year 3 awarded by National Institutes of Health 2014 - 2015
- Southern Consortium Node of the Clinical Trials Network awarded by Medical University of South Carolina 2013 - 2015
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Magnani, JW, Zhu, L, Lopez, F, Pencina, MJ, Agarwal, SK, Soliman, EZ, Benjamin, EJ, and Alonso, A. "P-wave indices and atrial fibrillation: Cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study (Accepted)." Mosby Inc., May 5, 2014. Full Text
- Journal Articles
  - Li, J, Feng, Q, Fine, JP, Pencina, MJ, and Van Calster, B. "Nonparametric estimation and inference for polytomous discrimination index." Statistical Methods in Medical Research 27, no. 10 (October 2018): 3092-3103. Full Text
  - Pagidipati, NJ, Hellkamp, AS, Sharma, PP, Wang, TY, Fonarow, GC, and Pencina, M. "High-sensitivity C-reactive protein elevation in patients with prior myocardial infarction in the United States." American Heart Journal 204 (October 1, 2018): 151-155. Full Text
  - Pencina, KM, D'Agostino, RB, Vasan, RS, and Pencina, MJ. "Microsimulation model to predict incremental value of biomarkers added to prognostic models." Journal of the American Medical Informatics Association : Jamia 25, no. 10 (October 2018): 1382-1385. Full Text
  - Carin, L, and Pencina, MJ. "On deep learning for medical image analysis." Jama Journal of the American Medical Association 320, no. 11 (September 18, 2018): 1192-1193. (Review) Full Text
  - Pencina, MJ, Rockhold, FW, and D'Agostino, RB. "Deriving Real-World Insights From Real-World Data: Biostatistics to the Rescue." Annals of Internal Medicine 169, no. 6 (September 2018): 401-402. Full Text
  - O'Brien, EC, Holmes, DN, Thomas, L, Singer, DE, Fonarow, GC, Mahaffey, KW, Kowey, PR, Hylek, EM, Pokorney, SD, Ansell, JE, Pencina, MJ, Peterson, ED, Piccini, JP, and ORBIT-AF Patients & Investigators, . "Incremental prognostic value of renal function for stroke prediction in atrial fibrillation." International Journal of Cardiology (July 25, 2018). Full Text
  - Navar, AM, Pencina, MJ, Mulder, H, Elias, P, and Peterson, ED. "Improving patient risk communication: Translating cardiovascular risk into standardized risk percentiles." American Heart Journal 198 (April 2018): 18-24. Full Text
  - Rosenstock, J, Perkovic, V, Alexander, JH, Cooper, ME, Marx, N, Pencina, MJ, Toto, RD, Wanner, C, Zinman, B, Baanstra, D, Pfarr, E, Mattheus, M, Broedl, UC, Woerle, H-J, George, JT, von Eynatten, M, McGuire, DK, and CARMELINA® investigators, . "Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk." Cardiovascular Diabetology 17, no. 1 (March 14, 2018): 39-null. Full Text
  - Isakova, T, Cai, X, Lee, J, Xie, D, Wang, X, Mehta, R, Allen, NB, Scialla, JJ, Pencina, MJ, Anderson, AH, Talierco, J, Chen, J, Fischer, MJ, Steigerwalt, SP, Leonard, MB, Hsu, C-Y, de Boer, IH, Kusek, JW, Feldman, HI, Wolf, M, and Chronic Renal Insufficiency Cohort (CRIC) Study Investigators, . "Longitudinal FGF23 Trajectories and Mortality in Patients with CKD." Journal of the American Society of Nephrology : Jasn 29, no. 2 (February 2018): 579-590. Full Text
  - Leening, MJG, and Pencina, MJ. "Absolute vs Additive Net Reclassification Index." JAMA 319, no. 6 (February 2018): 616-. (Letter) Full Text
  - Pencina, MJ, Chipman, J, Steyerberg, EW, Braun, D, Fine, JP, and D'Agostino, RB. "Authors' response to comments." Statistics in Medicine 36, no. 28 (December 2017): 4511-4513. Full Text
  - Pencina, MJ, Fine, JP, and D'Agostino, RB. "Discrimination slope and integrated discrimination improvement - properties, relationships and impact of calibration." Statistics in Medicine 36, no. 28 (December 2017): 4482-4490. Full Text
  - Pencina, MJ, Steyerberg, EW, and D'Agostino, RB. "Net reclassification index at event rate: properties and relationships." Statistics in Medicine 36, no. 28 (December 2017): 4455-4467. Full Text
  - Burstein, B, Altobelli, KK, Williams, K, Cannon, CP, Pencina, MJ, Sniderman, AD, and Thanassoulis, G. "Impact of Heart Outcomes Prevention Evaluation Trial on Statin Eligibility for the Primary Prevention of Cardiovascular Disease: Insights from the National Health and Nutrition Examination Survey." Circulation 136, no. 19 (November 2017): 1860-1862. (Letter) Full Text
  - Thanassoulis, G, Pencina, MJ, and Sniderman, AD. "The Benefit Model for Prevention of Cardiovascular Disease: An Opportunity to Harmonize Guidelines." JAMA cardiology 2, no. 11 (November 2017): 1175-1176. Full Text
  - Rybin, D, Lew, R, Pencina, MJ, Fava, M, and Doros, G. "Placebo Response as a Latent Characteristic: Application to Analysis of Sequential Parallel Comparison Design Studies." Journal of the American Statistical Association (September 29, 2017): 0-0. Full Text
  - Demler, OV, Pencina, MJ, Cook, NR, and D'Agostino, RB. "Asymptotic distribution of ∆AUC, NRIs, and IDI based on theory of U-statistics." Statistics in Medicine 36, no. 21 (September 2017): 3334-3360. Full Text
  - Pagidipati, NJ, Navar, AM, and Pencina, MJ. "Guideline Recommendations for Statin Therapy-Reply." JAMA 318, no. 10 (September 2017): 964-. (Letter) Full Text
  - Awad, K, Mikhailidis, DP, Toth, PP, Jones, SR, Moriarty, P, Lip, GYH, Muntner, P, Catapano, AL, Pencina, MJ, Rosenson, RS, Rysz, J, Banach, M, and Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group, . "Efficacy and Safety of Alternate-Day Versus Daily Dosing of Statins: a Systematic Review and Meta-Analysis." Cardiovascular Drugs and Therapy 31, no. 4 (August 2017): 419-431. (Review) Full Text
  - Calis, KA, Archdeacon, P, Bain, R, DeMets, D, Donohue, M, Elzarrad, MK, Forrest, A, McEachern, J, Pencina, MJ, Perlmutter, J, and Lewis, RJ. "Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative." Clinical Trials (London, England) 14, no. 4 (August 2017): 342-348. Full Text
  - Brennan, JM, Thomas, L, Cohen, DJ, Shahian, D, Wang, A, Mack, MJ, Holmes, DR, Edwards, FH, Frankel, NZ, Baron, SJ, Carroll, J, Thourani, V, Tuzcu, EM, Arnold, SV, Cohn, R, Maser, T, Schawe, B, Strong, S, Stickfort, A, Patrick-Lake, E, Graham, FL, Dai, D, Li, F, Matsouaka, RA, O'Brien, S, Pencina, MJ, and Peterson, ED. "Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison." Journal of the American College of Cardiology 70, no. 4 (July 2017): 439-450. Full Text
  - Goldstein, BA, Pomann, GM, Winkelmayer, WC, and Pencina, MJ. "A comparison of risk prediction methods using repeated observations: an application to electronic health records for hemodialysis." Statistics in Medicine 36, no. 17 (July 2017): 2750-2763. Full Text
  - Nagarajan, V, Fonarow, GC, Ju, C, Pencina, M, Laskey, WK, Maddox, TM, Hernandez, A, and Bhatt, DL. "Seasonal and circadian variations of acute myocardial infarction: Findings from the Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) program." American heart journal 189 (July 2017): 85-93. Full Text
  - Hoffmann, U, Ferencik, M, Udelson, JE, Picard, MH, Truong, QA, Patel, MR, Huang, M, Pencina, M, Mark, DB, Heitner, JF, Fordyce, CB, Pellikka, PA, Tardif, J-C, Budoff, M, Nahhas, G, Chow, B, Kosinski, AS, Lee, KL, Douglas, PS, and PROMISE Investigators, . "Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain: Insights From the PROMISE Trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain)." Circulation 135, no. 24 (June 2017): 2320-2332. Full Text
  - Fleming, TR, DeMets, DL, Roe, MT, Wittes, J, Calis, KA, Vora, AN, Meisel, A, Bain, RP, Konstam, MA, Pencina, MJ, Gordon, DJ, Mahaffey, KW, Hennekens, CH, Neaton, JD, Pearson, GD, Andersson, TL, Pfeffer, MA, and Ellenberg, SS. "Rejoinder." Clinical Trials (London, England) 14, no. 2 (April 2017): 126-127. Full Text
  - Fleming, TR, DeMets, DL, Roe, MT, Wittes, J, Calis, KA, Vora, AN, Meisel, A, Bain, RP, Konstam, MA, Pencina, MJ, Gordon, DJ, Mahaffey, KW, Hennekens, CH, Neaton, JD, Pearson, GD, Andersson, TL, Pfeffer, MA, and Ellenberg, SS. "Data monitoring committees: Promoting best practices to address emerging challenges." Clinical Trials (London, England) 14, no. 2 (April 2017): 115-123. Full Text
  - Pagidipati, NJ, Navar, AM, Mulder, H, Sniderman, AD, Peterson, ED, and Pencina, MJ. "Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines." Jama 317, no. 15 (April 2017): 1563-1567. Full Text
  - Spratt, SE, Pereira, K, Granger, BB, Batch, BC, Phelan, M, Pencina, M, Miranda, ML, Boulware, E, Lucas, JE, Nelson, CL, Neely, B, Goldstein, BA, Barth, P, Richesson, RL, Riley, IL, Corsino, L, McPeek Hinz, ER, Rusincovitch, S, Green, J, Barton, AB, DDC Phenotype Group, , Kelley, C, Hyland, K, Tang, M, Elliott, A, Ruel, E, Clark, A, Mabrey, M, Morrissey, KL, Rao, J, Hong, B, Pierre-Louis, M, Kelly, K, and Jelesoff, N. "Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus." Journal of the American Medical Informatics Association : Jamia 24, no. e1 (April 2017): e121-e128. Full Text
  - Stolker, JM, Cohen, DJ, Kennedy, KF, Pencina, MJ, Arnold, SV, Kleiman, NS, Spertus, JA, and EVENT Investigators, . "Combining clinical and angiographic variables for estimating risk of target lesion revascularization after drug eluting stent placement." Cardiovascular revascularization medicine : including molecular interventions 18, no. 3 (April 2017): 169-176. Full Text
  - Xian, Y, O'Brien, EC, Liang, L, Xu, H, Schwamm, LH, Fonarow, GC, Bhatt, DL, Smith, EE, Olson, DM, Maisch, L, Hannah, D, Lindholm, B, Lytle, BL, Pencina, MJ, Hernandez, AF, and Peterson, ED. "Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation." Jama 317, no. 10 (March 2017): 1057-1067. Full Text
  - Kopeć, G, Waligóra, M, Tyrka, A, Jonas, K, Pencina, MJ, Zdrojewski, T, Moertl, D, Stokwiszewski, J, Zagożdżon, P, and Podolec, P. "Low-density lipoprotein cholesterol and survival in pulmonary arterial hypertension." Scientific reports 7 (February 15, 2017): 41650-. Full Text
  - Goldstein, BA, Navar, AM, Pencina, MJ, and Ioannidis, JPA. "Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review." Journal of the American Medical Informatics Association : Jamia 24, no. 1 (January 2017): 198-208. (Review) Full Text
  - Goldstein, BA, Pencina, MJ, Montez-Rath, ME, and Winkelmayer, WC. "Predicting mortality over different time horizons: which data elements are needed?." Journal of the American Medical Informatics Association : Jamia 24, no. 1 (January 2017): 176-181. Full Text
  - Sharma, A, Bigelow, RH, and Pencina, MJ. "Scientific, societal, and economic consequences of releasing interim data from clinical trials." European Heart Journal. Quality of Care & Clinical Outcomes 3, no. 1 (January 2017): 9-10. Full Text
  - Barnhart, HX, Yow, E, Crowley, AL, Daubert, MA, Rabineau, D, Bigelow, R, Pencina, M, and Douglas, PS. "Choice of agreement indices for assessing and improving measurement reproducibility in a core laboratory setting." Statistical methods in medical research 25, no. 6 (December 2016): 2939-2958. Full Text
  - Crowley, AL, Yow, E, Barnhart, HX, Daubert, MA, Bigelow, R, Sullivan, DC, Pencina, M, and Douglas, PS. "Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography 29, no. 12 (December 2016): 1144-1154.e7. (Review) Full Text
  - Goldstein, BA, Bhavsar, NA, Phelan, M, and Pencina, MJ. "Controlling for Informed Presence Bias Due to the Number of Health Encounters in an Electronic Health Record." American Journal of Epidemiology 184, no. 11 (December 2016): 847-855. Full Text
  - Goldstein, BA, Navar, AM, and Pencina, MJ. "Risk Prediction With Electronic Health Records: The Importance of Model Validation and Clinical Context." Jama Cardiology 1, no. 9 (December 2016): 976-977. Full Text
  - Pandey, A, Golwala, H, Xu, H, DeVore, AD, Matsouaka, R, Pencina, M, Kumbhani, DJ, Hernandez, AF, Bhatt, DL, Heidenreich, PA, Yancy, CW, de Lemos, JA, and Fonarow, GC. "Association of 30-Day Readmission Metric for Heart Failure Under the Hospital Readmissions Reduction Program With Quality of Care and Outcomes." Jacc. Heart Failure 4, no. 12 (December 2016): 935-946. Full Text
  - Robinson, JG, Huijgen, R, Ray, K, Persons, J, Kastelein, JJP, and Pencina, MJ. "Determining When to Add Nonstatin Therapy: A Quantitative Approach." Journal of the American College of Cardiology 68, no. 22 (December 2016): 2412-2421. (Review) Full Text
  - Thomas, LE, and Pencina, MJ. "Do Not Over (P) Value Your Research Article." JAMA cardiology 1, no. 9 (December 2016): 1055-. Full Text
  - Wilson, PWF, and Pencina, MJ. "Estimation of Risk for Initial Atherosclerotic Cardiovascular Disease Events: Taking Stock and Moving Forward." Circulation 134, no. 23 (December 2016): 1792-1793. Full Text
  - Ngwa, JS, Cabral, HJ, Cheng, DM, Pencina, MJ, Gagnon, DR, LaValley, MP, and Cupples, LA. "A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study." Bmc Medical Research Methodology 16, no. 1 (November 3, 2016): 148-null. Full Text
  - Ngwa, JS, Cabral, HJ, Cheng, DM, Pencina, MJ, Gagnon, DR, LaValley, MP, and Cupples, LA. "A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study." BMC medical research methodology 16, no. 1 (November 3, 2016): 148-.
  - Hornik, CP, Benjamin, DK, Smith, PB, Pencina, MJ, Tremoulet, AH, Capparelli, EV, Ericson, JE, Clark, RH, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act—Pediatric Trials Network, . "Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates." The Journal of Pediatrics 178 (November 2016): 125-129.e1. Full Text
  - Navar, AM, Pencina, MJ, and Peterson, ED. "Assessing Cardiovascular Risk to Guide Hypertension Diagnosis and Treatment." Jama Cardiology 1, no. 8 (November 2016): 864-871. Full Text
  - Navar, AM, Peterson, ED, Wojdyla, D, Sanchez, RJ, Sniderman, AD, D'Agostino, RB, and Pencina, MJ. "Temporal Changes in the Association Between Modifiable Risk Factors and Coronary Heart Disease Incidence." Jama 316, no. 19 (November 2016): 2041-2043. (Letter) Full Text
  - Sniderman, AD, Islam, S, McQueen, M, Pencina, M, Furberg, CD, Thanassoulis, G, and Yusuf, S. "Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low-Density Lipoprotein Cholesterol or Non-High-Density Lipoprotein Cholesterol." Journal of the American Heart Association 5, no. 10 (October 13, 2016). Full Text
  - Chruściel, P, Sahebkar, A, Rembek-Wieliczko, M, Serban, M-C, Ursoniu, S, Mikhailidis, DP, Jones, SR, Mosteoru, S, Blaha, MJ, Martin, SS, Rysz, J, Toth, PP, Lip, GYH, Pencina, MJ, Ray, KK, Banach, M, and Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group, . "Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms." Atherosclerosis 253 (October 2016): 194-208. (Review) Full Text
  - O'Brien, EC, Xian, Y, Xu, H, Wu, J, Saver, JL, Smith, EE, Schwamm, LH, Peterson, ED, Reeves, MJ, Bhatt, DL, Maisch, L, Hannah, D, Lindholm, B, Olson, D, Prvu Bettger, J, Pencina, M, Hernandez, AF, and Fonarow, GC. "Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research)." Stroke 47, no. 10 (October 2016): 2627-2633. Full Text
  - Lee, JC, Zdrojewski, T, Pencina, MJ, Wyszomirski, A, Lachacz, M, Opolski, G, Bandosz, P, Rutkowski, M, Gaciong, Z, Wyrzykowski, B, and Navar, AM. "Population Effect of Differences in Cholesterol Guidelines in Eastern Europe and the United States." Jama Cardiology 1, no. 6 (September 2016): 700-707. Full Text
  - Clement, ME, Park, LP, Navar, AM, Okeke, NL, Pencina, MJ, Douglas, PS, and Naggie, S. "Statin Utilization and Recommendations Among HIV- and HCV-infected Veterans: A Cohort Study." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 63, no. 3 (August 2016): 407-413. Full Text
  - Navar, AM, Pencina, MJ, and Peterson, ED. "Open Access Platforms for Sharing Clinical Trial Data--Reply." JAMA 316, no. 6 (August 2016): 666-667. (Letter) Full Text
  - Sniderman, AD, Thanassoulis, G, Williams, K, and Pencina, M. "Risk of Premature Cardiovascular Disease vs the Number of Premature Cardiovascular Events." JAMA Cardiology 1, no. 4 (July 1, 2016): 492-492. Full Text
  - Banach, M, Serban, M-C, Sahebkar, A, García-García, HM, Mikhailidis, DP, Martin, SS, Brie, D, Rysz, J, Toth, PP, Jones, SR, Hasan, RK, Mosteoru, S, Al Rifai, M, Pencina, MJ, and Serruys, PW. "Comparison of clinical outcomes between bioresorbable vascular stents versus conventional drug-eluting and metallic stents: a systematic review and meta-analysis." EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 12, no. 2 (June 2016): e175-e189. (Review) Full Text
  - Van Calster, B, Nieboer, D, Vergouwe, Y, De Cock, B, Pencina, MJ, and Steyerberg, EW. "A calibration hierarchy for risk models was defined: from utopia to empirical data." Journal of Clinical Epidemiology 74 (June 2016): 167-176. Full Text
  - McGuire, DK, Van de Werf, F, Armstrong, PW, Standl, E, Koglin, J, Green, JB, Bethel, MA, Cornel, JH, Lopes, RD, Halvorsen, S, Ambrosio, G, Buse, JB, Josse, RG, Lachin, JM, Pencina, MJ, Garg, J, Lokhnygina, Y, Holman, RR, Peterson, ED, and Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) Study Group, . "Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial." Jama Cardiology 1, no. 2 (May 2016): 126-135. Full Text
  - Mentz, RJ, Newby, LK, Neely, B, Lucas, JE, Pokorney, SD, Rao, MP, Jackson, LR, Grau-Sepulveda, MV, Smerek, MM, Barth, P, Nelson, CL, Pencina, MJ, and Shah, BR. "Assessment of Administrative Data to Identify Acute Myocardial Infarction in Electronic Health Records." Journal of the American College of Cardiology 67, no. 20 (May 2016): 2441-2442. (Letter) Full Text
  - Pagidipati, NJ, Pencina, M, and Sniderman, AD. "The Enigma of Glucose and Lipid Metabolism." Jama Cardiology 1, no. 2 (May 2016): 145-146. Full Text
  - Banovic, M, Iung, B, Bartunek, J, Asanin, M, Beleslin, B, Biocina, B, Casselman, F, da Costa, M, Deja, M, Gasparovic, H, Kala, P, Labrousse, L, Loncar, Z, Marinkovic, J, Nedeljkovic, I, Nedeljkovic, M, Nemec, P, Nikolic, SD, Pencina, M, Penicka, M, Ristic, A, Sharif, F, Van Camp, G, Vanderheyden, M, Wojakowski, W, and Putnik, S. "Rationale and design of the Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): A randomized multicenter controlled event-driven trial." American heart journal 174 (April 2016): 147-153. Full Text
  - Fox, ER, Samdarshi, TE, Musani, SK, Pencina, MJ, Sung, JH, Bertoni, AG, Xanthakis, V, Balfour, PC, Shreenivas, SS, Covington, C, Liebson, PR, Sarpong, DF, Butler, KR, Mosley, TH, Rosamond, WD, Folsom, AR, Herrington, DM, Vasan, RS, and Taylor, HA. "Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA cardiology 1, no. 1 (April 2016): 15-25. Full Text
  - Holman, RR, Bethel, MA, George, J, Sourij, H, Doran, Z, Keenan, J, Khurmi, NS, Mentz, RJ, Oulhaj, A, Buse, JB, Chan, JC, Iqbal, N, Kundu, S, Maggioni, AP, Marso, SP, Öhman, P, Pencina, MJ, Poulter, N, Porter, LE, Ramachandran, A, Zinman, B, and Hernandez, AF. "Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial." American Heart Journal 174 (April 2016): 103-110. Full Text
  - Pencina, MJ, and Peterson, ED. "Moving From Clinical Trials to Precision Medicine: The Role for Predictive Modeling." JAMA 315, no. 16 (April 2016): 1713-1714. Full Text
  - Thanassoulis, G, Williams, K, Altobelli, KK, Pencina, MJ, Cannon, CP, and Sniderman, AD. "Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease." Circulation 133, no. 16 (April 2016): 1574-1581. Full Text
  - Navar, AM, Pencina, MJ, Rymer, JA, Louzao, DM, and Peterson, ED. "Use of Open Access Platforms for Clinical Trial Data." JAMA 315, no. 12 (March 2016): 1283-1284. Full Text
  - Pencina, MJ, Louzao, DM, McCourt, BJ, Adams, MR, Tayyabkhan, RH, Ronco, P, and Peterson, ED. "Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative." American heart journal 172 (February 2016): 64-69. (Review) Full Text
  - Sahebkar, A, Serban, M-C, Mikhailidis, DP, Toth, PP, Muntner, P, Ursoniu, S, Mosterou, S, Glasser, S, Martin, SS, Jones, SR, Rizzo, M, Rysz, J, Sniderman, AD, Pencina, MJ, Banach, M, and Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group, . "Head-to-head comparison of statins versus fibrates in reducing plasma fibrinogen concentrations: A systematic review and meta-analysis." Pharmacological research 103 (January 2016): 236-252. (Review) Full Text
  - Zdrojewski, T, Solnica, B, Cybulska, B, Bandosz, P, Rutkowski, M, Stokwiszewski, J, Gaciong, Z, Banach, M, Wojtyniak, B, Pencina, M, and Wyrzykowski, B. "Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey." Kardiologia Polska 74, no. 3 (January 2016): 213-223. Full Text
  - O'Brien, EC, Simon, DJN, Thomas, LE, Hylek, EM, Gersh, BJ, Ansell, JE, Kowey, PR, Mahaffey, KW, Chang, P, Fonarow, GC, Pencina, MJ, Piccini, JP, and Peterson, ED. "The ORBIT bleeding score: A simple bedside score to assess bleeding risk in atrial fibrillation." European Heart Journal 36, no. 46 (December 7, 2015): 3258-3264. Full Text
  - O'Brien, EC, Simon, DN, Thomas, LE, Hylek, EM, Gersh, BJ, Ansell, JE, Kowey, PR, Mahaffey, KW, Chang, P, Fonarow, GC, Pencina, MJ, Piccini, JP, and Peterson, ED. "The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation." European Heart Journal 36, no. 46 (December 2015): 3258-3264. Full Text Open Access Copy
  - Shelton, RC, Pencina, MJ, Barrentine, LW, Ruiz, JA, Fava, M, Zajecka, JM, and Papakostas, GI. "Association of obesity and inflammatory marker levels on treatment outcome: results from a double-blind, randomized study of adjunctive L-methylfolate calcium in patients with MDD who are inadequate responders to SSRIs." The Journal of clinical psychiatry 76, no. 12 (December 2015): 1635-1641. Full Text
  - Sniderman, AD, D'Agostino, RB, and Pencina, MJ. "Risk Prediction for Individuals--Reply." JAMA 314, no. 17 (November 2015): 1875-1876. (Letter) Full Text
  - Wu, L-T, Ghitza, UE, Batch, BC, Pencina, MJ, Rojas, LF, Goldstein, BA, Schibler, T, Dunham, AA, Rusincovitch, S, and Brady, KT. "Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data." Drug and alcohol dependence 156 (November 2015): 162-169. Full Text
  - Navar-Boggan, AM, Peterson, ED, D'Agostino, RB, Neely, B, Sniderman, AD, and Pencina, MJ. "Response to Letter Regarding Article, "Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease"." Circulation 132, no. 16 (October 2015): e203-. (Letter) Full Text
  - O'Brien, EC, Greiner, MA, Xian, Y, Fonarow, GC, Olson, DM, Schwamm, LH, Bhatt, DL, Smith, EE, Maisch, L, Hannah, D, Lindholm, B, Peterson, ED, Pencina, MJ, and Hernandez, AF. "Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study." Circulation 132, no. 15 (October 2015): 1404-1413. Full Text
  - Pencina, MJ, D'Agostino, RB, Zdrojewski, T, Williams, K, Thanassoulis, G, Furberg, CD, Peterson, ED, Vasan, RS, and Sniderman, AD. "Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C." European Journal of Preventive Cardiology 22, no. 10 (October 2015): 1321-1327. Full Text
  - Sinning, J-M, Wollert, KC, Sedaghat, A, Widera, C, Radermacher, M-C, Descoups, C, Hammerstingl, C, Weber, M, Stundl, A, Ghanem, A, Widder, J, Vasa-Nicotera, M, Mellert, F, Schiller, W, Bauersachs, J, Zur, B, Holdenrieder, S, Welz, A, Grube, E, Pencina, MJ, Nickenig, G, Werner, N, and Kempf, T. "Risk scores and biomarkers for the prediction of 1-year outcome after transcatheter aortic valve replacement." American Heart Journal 170, no. 4 (October 2015): 821-829. Full Text
  - Wechsler, ME, Yawn, BP, Fuhlbrigge, AL, Pace, WD, Pencina, MJ, Doros, G, Kazani, S, Raby, BA, Lanzillotti, J, Madison, S, Israel, E, and BELT Investigators, . "Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial." Jama 314, no. 16 (October 2015): 1720-1730. Full Text
  - Ko, MJ, Kim, YJ, Park, CM, Lee, S-M, Lee, WJ, Pencina, MJ, Navar-Boggan, AM, and Park, D-W. "Applicability and potential clinical effects of 2013 cholesterol guidelines on major cardiovascular events." American heart journal 170, no. 3 (September 2015): 598-605.e7. Full Text
  - Pencina, MJ, and D'Agostino, RB. "Evaluating Discrimination of Risk Prediction Models: The C Statistic." Jama 314, no. 10 (September 2015): 1063-1064. Full Text
  - Fine, JP, and Pencina, M. "On the quantitative assessment of predictive biomarkers." Journal of the National Cancer Institute 107, no. 8 (August 2015). Full Text
  - Jansen, H, Loley, C, Lieb, W, Pencina, MJ, Nelson, CP, Kathiresan, S, Peloso, GM, Voight, BF, Reilly, MP, Assimes, TL, Boerwinkle, E, Hengstenberg, C, Laaksonen, R, McPherson, R, Roberts, R, Thorsteinsdottir, U, Peters, A, Gieger, C, Rawal, R, Thompson, JR, König, IR, CARDIoGRAM consortium, , Vasan, RS, Erdmann, J, Samani, NJ, and Schunkert, H. "Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk." Atherosclerosis 241, no. 2 (August 2015): 419-426. Full Text
  - Min, JK, Dunning, A, Gransar, H, Achenbach, S, Lin, FY, Al-Mallah, M, Budoff, MJ, Callister, TQ, Chang, H-J, Cademartiri, F, Maffei, E, Chinnaiyan, K, Chow, BJW, D'Agostino, R, DeLago, A, Friedman, J, Hadamitzky, M, Hausleiter, J, Hayes, SW, Kaufmann, P, Raff, GL, Shaw, LJ, Thomson, L, Villines, T, Cury, RC, Feuchtner, G, Kim, Y-J, Leipsic, J, Marques, H, Berman, DS, and Pencina, M. "Medical history for prognostic risk assessment and diagnosis of stable patients with suspected coronary artery disease." The American journal of medicine 128, no. 8 (August 2015): 871-878. Full Text
  - Xian, Y, Wu, J, O'Brien, EC, Fonarow, GC, Olson, DM, Schwamm, LH, Bhatt, DL, Smith, EE, Suter, RE, Hannah, D, Lindholm, B, Maisch, L, Greiner, MA, Lytle, BL, Pencina, MJ, Peterson, ED, and Hernandez, AF. "Real world effectiveness of warfarin among ischemic stroke patients with atrial fibrillation: observational analysis from Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) study." BMJ (Clinical research ed.) 351 (July 31, 2015): h3786-. Full Text
  - Goff, DC, D'Agostino, RB, Pencina, M, and Lloyd-Jones, DM. "Calibration and Discrimination Among Multiple Cardiovascular Risk Scores in a Modern Multiethnic Cohort." Annals of internal medicine 163, no. 1 (July 2015): 68-. (Letter) Full Text
  - Green, JB, Bethel, MA, Armstrong, PW, Buse, JB, Engel, SS, Garg, J, Josse, R, Kaufman, KD, Koglin, J, Korn, S, Lachin, JM, McGuire, DK, Pencina, MJ, Standl, E, Stein, PP, Suryawanshi, S, Van de Werf, F, Peterson, ED, Holman, RR, and TECOS Study Group, . "Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes." The New England Journal of Medicine 373, no. 3 (July 2015): 232-242. Full Text
  - Navar, AM, and Pencina, M. "ACP Journal Club. In adults without CV disease, most prediction scores overestimated risk for atherosclerotic CV events." Annals of internal medicine 163, no. 2 (July 2015): JC13-. Full Text
  - Rybin, D, Doros, G, Pencina, MJ, and Fava, M. "Placebo non-response measure in sequential parallel comparison design studies." Statistics in medicine 34, no. 15 (July 2015): 2281-2293. Full Text
  - Sniderman, AD, D'Agostino, RB, and Pencina, MJ. "The Role of Physicians in the Era of Predictive Analytics." Jama 314, no. 1 (July 2015): 25-26. Full Text
  - Steyerberg, EW, Vedder, MM, Leening, MJG, Postmus, D, D'Agostino, RB, Van Calster, B, and Pencina, MJ. "Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives." Biometrical journal. Biometrische Zeitschrift 57, no. 4 (July 2015): 556-570. Full Text
  - Xian, Y, O'Brien, EC, Fonarow, GC, Olson, DM, Schwamm, LH, Hannah, D, Lindholm, B, Maisch, L, Lytle, BL, Greiner, MA, Wu, J, Peterson, ED, Pencina, MJ, and Hernandez, AF. "Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research: Implementing the patient-driven research paradigm to aid decision making in stroke care." American heart journal 170, no. 1 (July 2015): 36-45.11. Full Text
  - Sniderman, AD, Pencina, M, and Thanassoulis, G. "Limitations in the conventional assessment of the incremental value of predictors of cardiovascular risk." Current opinion in lipidology 26, no. 3 (June 2015): 210-214. (Review) Full Text
  - Bandosz, P, O'Flaherty, M, Rutkowski, M, Kypridemos, C, Guzman-Castillo, M, Gillespie, DOS, Solnica, B, Pencina, MJ, Wyrzykowski, B, Capewell, S, and Zdrojewski, T. "A victory for statins or a defeat for diet policies? Cholesterol falls in Poland in the past decade: A modeling study." International journal of cardiology 185 (April 2015): 313-319. Full Text
  - Mühlenbruch, K, Kuxhaus, O, Pencina, MJ, Boeing, H, Liero, H, and Schulze, MB. "A confidence ellipse for the Net Reclassification Improvement." European Journal of Epidemiology 30, no. 4 (April 2015): 299-304. Full Text
  - Navar-Boggan, AM, Peterson, ED, D'Agostino, RB, Pencina, MJ, and Sniderman, AD. "Using age- and sex-specific risk thresholds to guide statin therapy: one size may not fit all." Journal of the American College of Cardiology 65, no. 16 (April 2015): 1633-1639. Full Text
  - Abraham, TM, Pencina, KM, Pencina, MJ, and Fox, CS. "Trends in diabetes incidence: the Framingham Heart Study." Diabetes Care 38, no. 3 (March 2015): 482-487. Full Text
  - Navar-Boggan, AM, Peterson, ED, D'Agostino, RB, Neely, B, Sniderman, AD, and Pencina, MJ. "Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease." Circulation 131, no. 5 (February 2015): 451-458. Full Text
  - Dallmeier, D, Pencina, MJ, Rajman, I, Koenig, W, Rothenbacher, D, and Brenner, H. "Serial measurements of N-terminal pro-brain natriuretic peptide in patients with coronary heart disease." PloS one 10, no. 1 (January 28, 2015): e0117143-. Full Text
  - Magnani, JW, Zhu, L, Lopez, F, Pencina, MJ, Agarwal, SK, Soliman, EZ, Benjamin, EJ, and Alonso, A. "P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study." American Heart Journal 169, no. 1 (January 2015): 53-61.e1. Full Text
  - Navar, AM, and Pencina, M. "In adults without CV disease, most prediction scores overestimated risk for atherosclerotic CV events." Annals of Internal Medicine 163, no. 2 (January 1, 2015): JC13-. Full Text
  - Pencina, MJ, Neely, B, and Steyerberg, EW. "RE: net risk reclassification P Values: valid or misleading?." Journal of the National Cancer Institute 107, no. 1 (January 2015): 355-null. (Letter) Full Text
  - Shao, F, Li, J, Fine, J, Wong, WK, and Pencina, M. "Inference for reclassification statistics under nested and non-nested models for biomarker evaluation." Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20, no. 4 (January 2015): 240-252. Full Text
  - Steyerberg, EW, Vedder, MM, Leening, MJG, Postmus, D, D'Agostino, RB, Calster, BV, and Pencina, MJ. "Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives." Biometrical Journal 57, no. 4 (2015): 556-570. Full Text
  - Pencina, KM, Pencina, MJ, and D'Agostino, RB. "What to expect from net reclassification improvement with three categories." Statistics in Medicine 33, no. 28 (December 10, 2014): 4975-4987. Full Text
  - Clark, CJ, Alonso, A, Spencer, RA, Pencina, M, Williams, K, and Everson-Rose, SA. "Predicted long-term cardiovascular risk among young adults in the national longitudinal study of adolescent health." American Journal of Public Health 104, no. 12 (December 2014): e108-e115. Full Text
  - Pencina, KM, Pencina, MJ, and D'Agostino, RB. "What to expect from net reclassification improvement with three categories." Statistics in Medicine 33, no. 28 (December 2014): 4975-4987. Full Text
  - Rutkowski, M, Bandosz, P, Czupryniak, L, Gaciong, Z, Solnica, B, Jasiel-Wojculewicz, H, Wyrzykowski, B, Pencina, MJ, and Zdrojewski, T. "Prevalence of diabetes and impaired fasting glucose in Poland--the NATPOL 2011 Study." Diabetic medicine : a journal of the British Diabetic Association 31, no. 12 (December 2014): 1568-1571. Full Text
  - Ahmad, T, Pencina, MJ, Schulte, PJ, O'Brien, E, Whellan, DJ, Piña, IL, Kitzman, DW, Lee, KL, O'Connor, CM, and Felker, GM. "Clinical implications of chronic heart failure phenotypes defined by cluster analysis." Journal of the American College of Cardiology 64, no. 17 (October 21, 2014): 1765-1774. Full Text
  - Ahmad, T, Fiuzat, M, Pencina, MJ, Geller, NL, Zannad, F, Cleland, JGF, Snider, JV, Blankenberg, S, Adams, KF, Redberg, RF, Kim, JB, Mascette, A, Mentz, RJ, O'Connor, CM, Felker, GM, and Januzzi, JL. "Charting a roadmap for heart failure biomarker studies." Jacc. Heart Failure 2, no. 5 (October 2014): 477-488. (Review) Full Text
  - Boone, MD, Celi, LA, Ho, BG, Pencina, M, Curry, MP, Lior, Y, Talmor, D, and Novack, V. "Model for End-Stage Liver Disease score predicts mortality in critically ill cirrhotic patients." Journal of critical care 29, no. 5 (October 2014): 881.e7-881.13. Full Text
  - Sinner, MF, Stepas, KA, Moser, CB, Krijthe, BP, Aspelund, T, Sotoodehnia, N, Fontes, JD, Janssens, ACJW, Kronmal, RA, Magnani, JW, Witteman, JC, Chamberlain, AM, Lubitz, SA, Schnabel, RB, Vasan, RS, Wang, TJ, Agarwal, SK, McManus, DD, Franco, OH, Yin, X, Larson, MG, Burke, GL, Launer, LJ, Hofman, A, Levy, D, Gottdiener, JS, Kääb, S, Couper, D, Harris, TB, Astor, BC, Ballantyne, CM, Hoogeveen, RC, Arai, AE, Soliman, EZ, Ellinor, PT, Stricker, BHC, Gudnason, V, Heckbert, SR, Pencina, MJ, Benjamin, EJ, and Alonso, A. "B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 16, no. 10 (October 2014): 1426-1433. Full Text
  - Baker, SG, Schuit, E, Steyerberg, EW, Pencina, MJ, Vickers, A, Moons, KGM, Mol, BWJ, and Lindeman, KS. "How to interpret a small increase in AUC with an additional risk prediction marker: Decision analysis comes through." Statistics in Medicine 33, no. 22 (September 28, 2014): 3946-3959. Full Text
  - Baker, SG, Schuit, E, Steyerberg, EW, Pencina, MJ, Vickers, A, Moons, KGM, Mol, BWJ, and Lindeman, KS. "How to interpret a small increase in AUC with an additional risk prediction marker: decision analysis comes through." Statistics in Medicine 33, no. 22 (September 2014): 3946-3959. Full Text
  - Chan, RH, Maron, BJ, Olivotto, I, Pencina, MJ, Assenza, GE, Haas, T, Lesser, JR, Gruner, C, Crean, AM, Rakowski, H, Udelson, JE, Rowin, E, Lombardi, M, Cecchi, F, Tomberli, B, Spirito, P, Formisano, F, Biagini, E, Rapezzi, C, De Cecco, CN, Autore, C, Cook, EF, Hong, SN, Gibson, CM, Manning, WJ, Appelbaum, E, and Maron, MS. "Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy." Circulation 130, no. 6 (August 2014): 484-495. Full Text
  - Hess, CN, Roe, MT, Gibson, CM, Temple, RJ, Pencina, MJ, Zarin, DA, Anstrom, KJ, Alexander, JH, Sherman, RE, Fiedorek, FT, Mahaffey, KW, Lee, KL, Chow, S-C, Armstrong, PW, and Califf, RM. "Independent data monitoring committees: preparing a path for the future." American Heart Journal 168, no. 2 (August 2014): 135-41.e1. Full Text
  - Leening, MJG, Steyerberg, EW, Van Calster, B, D'Agostino, RB, and Pencina, MJ. "Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective." Statistics in medicine 33, no. 19 (August 2014): 3415-3418. Full Text
  - Marino, M, Li, Y, Pencina, MJ, D'Agostino, RB, Berkman, LF, and Buxton, OM. "Quantifying cardiometabolic risk using modifiable non-self-reported risk factors." American Journal of Preventive Medicine 47, no. 2 (August 2014): 131-140. Full Text
  - Navar-Boggan, AM, Pencina, MJ, and Peterson, ED. "Patients affected by changes to hypertension guideline--reply." JAMA 312, no. 8 (August 2014): 846-847. (Letter) Full Text
  - Xanthakis, V, Sullivan, LM, Vasan, RS, Benjamin, EJ, Massaro, JM, D'Agostino, RB, and Pencina, MJ. "Assessing the incremental predictive performance of novel biomarkers over standard predictors." Statistics in Medicine 33, no. 15 (July 10, 2014): 2577-2584. Full Text
  - Michalska, M, Rysz, J, Pencina, MJ, Zdrojewski, T, and Banach, M. "The knowledge and awareness of hypertension among patients with hypertension in central Poland: a pilot registry." Angiology 65, no. 6 (July 2014): 525-532. Full Text
  - Navar-Boggan, AM, Sniderman, AD, and Pencina, MJ. "Application of the new cholesterol guidelines." The New England Journal of Medicine 371, no. 1 (July 2014): 79-null. (Letter) Full Text
  - Pen, A, Yam, Y, Chen, L, Dorbala, S, Di Carli, MF, Merhige, ME, Williams, BA, Veladar, E, Min, JK, Pencina, MJ, Berman, DS, Beanlands, RS, Shaw, LJ, and Chow, BJW. "Prognostic value of Rb-82 positron emission tomography myocardial perfusion imaging in coronary artery bypass patients." European heart journal cardiovascular Imaging 15, no. 7 (July 2014): 787-792. Full Text
  - Piotrowicz, E, Pencina, M, Piotrowski, W, Banach, M, and Piotrowicz, R. "Influence of exercise training on T-wave alternans assessed during exercise test in heart failure patients." International journal of cardiology 174, no. 3 (July 2014): 747-749. (Letter) Full Text
  - Vardi, M, Piazza, G, Pencina, MJ, Burke, DA, Lei, L, Goldhaber, SZ, and Cutlip, DE. "Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention." Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20, no. 5 (July 2014): 478-483. Full Text
  - Xanthakis, V, Sullivan, LM, Vasan, RS, Benjamin, EJ, Massaro, JM, D'Agostino, RB, and Pencina, MJ. "Assessing the incremental predictive performance of novel biomarkers over standard predictors." Statistics in medicine 33, no. 15 (July 2014): 2577-2584. Full Text
  - Ahmad, T, Fiuzat, M, Neely, B, Neely, ML, Pencina, MJ, Kraus, WE, Zannad, F, Whellan, DJ, Donahue, MP, Piña, IL, Adams, KF, Kitzman, DW, O'Connor, CM, and Felker, GM. "Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure." Jacc. Heart Failure 2, no. 3 (June 2014): 260-268. Full Text
  - Bangalore, S, Pencina, MJ, Kleiman, NS, and Cohen, DJ. "Heparin monotherapy or bivalirudin during percutaneous coronary intervention in patients with non-ST-segment-elevation acute coronary syndromes or stable ischemic heart disease: results from the Evaluation of Drug-Eluting Stents and Ischemic Events registry." Circulation. Cardiovascular interventions 7, no. 3 (June 2014): 365-373. Full Text
  - Van Calster, B, Steyerberg, EW, D'Agostino, RB, and Pencina, MJ. "Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models." Med Decis Making 34, no. 4 (May 2014): 513-522. Full Text Link to Item
  - Vardi, M, Novack, V, Pencina, MJ, Doros, G, Burke, DA, Elmariah, S, Cutlip, DE, Mauri, L, and Yeh, RW. "Safety and efficacy metrics for primary nitinol stenting in femoropopliteal occlusive disease: A meta-analysis and critical examination of current methodologies." Catheterization and Cardiovascular Interventions 83, no. 6 (May 1, 2014): 975-983. Full Text
  - Vardi, M, Novack, V, Pencina, MJ, Doros, G, Burke, DA, Elmariah, S, Cutlip, DE, Mauri, L, and Yeh, RW. "Safety and efficacy metrics for primary nitinol stenting in femoropopliteal occlusive disease: a meta-analysis and critical examination of current methodologies." Catheter Cardiovasc Interv 83, no. 6 (May 1, 2014): 975-983. (Review) Full Text Link to Item
  - Navar-Boggan, AM, Pencina, MJ, Williams, K, Sniderman, AD, and Peterson, ED. "Proportion of US adults potentially affected by the 2014 hypertension guideline." Jama 311, no. 14 (April 2014): 1424-1429. Full Text
  - Pencina, MJ, Navar-Boggan, AM, D'Agostino, RB, Williams, K, Neely, B, Sniderman, AD, and Peterson, ED. "Application of new cholesterol guidelines to a population-based sample." The New England Journal of Medicine 370, no. 15 (April 2014): 1422-1431. Full Text
  - Chow, BJW, Dorbala, S, Di Carli, MF, Merhige, ME, Williams, BA, Veledar, E, Min, JK, Pencina, MJ, Yam, Y, Chen, L, Anand, SP, Ruddy, TD, Berman, DS, Shaw, LJ, and Beanlands, RS. "Prognostic value of PET myocardial perfusion imaging in obese patients." JACC. Cardiovascular imaging 7, no. 3 (March 2014): 278-287. Full Text
  - Fox, CS, Pencina, MJ, Heard-Costa, NL, Shrader, P, Jaquish, C, O'Donnell, CJ, Vasan, RS, Cupples, LA, and D'Agostino, RB. "Trends in the association of parental history of obesity over 60 years." Obesity (Silver Spring) 22, no. 3 (March 2014): 919-924. Full Text Link to Item
  - Ren, X, Banki, NM, Shaw, RE, McNulty, EJ, Williams, SC, Pencina, M, and Schiller, NB. "Doppler-detected valve movement in aortic stenosis: a predictor of adverse outcome." Clinical cardiology 37, no. 3 (March 2014): 167-171. Full Text
  - Ahmad, T, Fiuzat, M, Pencina, MJ, Geller, NL, Zannad, F, Cleland, JGF, Snider, JV, Blankenberg, S, Adams, KF, Redberg, RF, Kim, JB, Mascette, A, Mentz, RJ, O'Connor, CM, Felker, GM, and Januzzi, JL. "Charting a roadmap for heart failure biomarker studies." JACC: Heart Failure 2, no. 5 (January 1, 2014): 477-488. (Review) Full Text
  - Avriel, A, Paryente Wiessman, M, Almog, Y, Perl, Y, Novack, V, Galante, O, Klein, M, Pencina, MJ, and Douvdevani, A. "Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care." Plos One 9, no. 6 (January 2014): e100514-null. Full Text
  - Baker, SG, Schuit, E, Steyerberg, EW, Pencina, MJ, Vickers, A, Moons, KGM, Mol, BWJ, and Lindeman, KS. "Correction to How to interpret a small increase in AUC with an additional risk prediction marker: Decision analysis comes through [Statist. Med. (2015) 33, 22, 3946-3959] DOI: 10.1002/sim.6195." Statistics in Medicine 34, no. 5 (January 1, 2014): 900-. Full Text
  - Boone, MD, Celi, LA, Ho, BG, Pencina, M, Curry, MP, Lior, Y, Talmor, D, and Novack, V. "Model for End-Stage Liver Disease score predicts mortality in critically ill cirrhotic patients." Journal of Critical Care 29, no. 5 (2014): 881.e7-881.e13. Full Text
  - Boone, MD, Celi, LA, Ho, BG, Pencina, M, Curry, MP, Lior, Y, Talmor, D, and Novack, V. "Model for End-Stage Liver Disease score predicts mortality in critically ill cirrhotic patients." Journal of Critical Care 29, no. 5 (2014): 881.e7-881.e13. Full Text
  - Chow, BJW, Dorbala, S, Di Carli, MF, Merhige, ME, Williams, BA, Veledar, E, Min, JK, Pencina, MJ, Yam, Y, Chen, L, Anand, SP, Ruddy, TD, Berman, DS, Shaw, LJ, and Beanlands, RS. "Prognostic value of PET myocardial perfusion imaging in obese patients." Jacc: Cardiovascular Imaging 7, no. 3 (January 1, 2014): 278-287. Full Text
  - Hess, CN, Roe, MT, Gibson, CM, J Temple, R, Pencina, MJ, Zarin, DA, Anstrom, KJ, Alexander, JH, Sherman, RE, Fiedorek, FT, Mahaffey, KW, Lee, KL, Chow, SC, Armstrong, PW, and Califf, RM. "Independent data monitoring committees: Preparing a path for the future." American Heart Journal 168, no. 2 (January 1, 2014). Full Text
  - Kemp, DE, Sylvia, LG, Calabrese, JR, Nierenberg, AA, Thase, ME, Reilly-Harrington, NA, Ostacher, MJ, Leon, AC, Ketter, TA, Friedman, ES, and al, E. "General medical burden in bipolar disorder: Findings from the LiTMUS comparative effectiveness trial." Acta Psychiatrica Scandinavica 129, no. 1 (2014): 24-34. Full Text
  - Leening, MJG, Vedder, MM, Witteman, JCM, Pencina, MJ, and Steyerberg, EW. "Net reclassification improvement: computation, interpretation, and controversies: a literature review and clinician's guide." Annals of Internal Medicine 160, no. 2 (January 2014): 122-131. (Review) Full Text
  - Marino, M, Li, Y, Pencina, MJ, D'Agostino, RB, Berkman, LF, and Buxton, OM. "Quantifying cardiometabolic risk using modifiable non-self-reported risk factors." American Journal of Preventive Medicine 47, no. 2 (January 1, 2014): 131-140. Full Text
  - Pencina, KM, Pencina, MJ, and D'Agostino, RB. "What to expect from net reclassification improvement with three categories (Accepted)." Statistics in Medicine (2014). Full Text
  - Piotrowicz, E, Pencina, M, Piotrowski, W, Banach, M, and Piotrowicz, R. "Influence of exercise training on T-wave alternans assessed during exercise test in heart failure patients." International Journal of Cardiology 174, no. 3 (2014): 747-749. Full Text
  - Ren, X, Banki, NM, Shaw, RE, McNulty, EJ, Williams, SC, Pencina, M, and Schiller, NB. "Doppler-detected valve movement in aortic stenosis: A predictor of adverse outcome." Clinical Cardiology 37, no. 3 (2014): 167-171. Full Text
  - Rutkowski, M, Bandosz, P, Czupryniak, L, Gaciong, Z, Solnica, B, Jasiel-Wojculewicz, H, Wyrzykowski, B, Pencina, MJ, and Zdrojewski, T. "Prevalence of diabetes and impaired fasting glucose in Poland-the NATPOL 2011 Study." Diabetic Medicine 31, no. 12 (January 1, 2014): 1568-1571. Full Text
  - Sniderman, AD, Toth, PP, Thanassoulis, G, Pencina, MJ, and Furberg, CD. "Taking a longer term view of cardiovascular risk: the causal exposure paradigm." Bmj (Clinical Research Ed.) 348 (January 2014): g3047-null. Full Text
  - Velagaleti, RS, Gona, P, Pencina, MJ, Aragam, J, Wang, TJ, Levy, D, D'Agostino, RB, Lee, DS, Kannel, WB, Benjamin, EJ, and Vasan, RS. "Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction." American Journal of Cardiology 113, no. 1 (January 1, 2014): 117-122. Full Text
  - Velagaleti, RS, Gona, P, Pencina, MJ, Aragam, J, Wang, TJ, Levy, D, D'Agostino, RB, Lee, DS, Kannel, WB, Benjamin, EJ, and Vasan, RS. "Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction." Am J Cardiol 113, no. 1 (January 1, 2014): 117-122. Full Text Link to Item
  - Bangalore, S, Pencina, MJ, Kleiman, NS, and Cohen, DJ. "Prognostic implications of procedural vs spontaneous myocardial infarction: Results from the Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry." American Heart Journal 166, no. 6 (December 1, 2013): 1027-1034. Full Text
  - Vardi, M, Burke, DA, Bangalore, S, Pencina, MJ, Mauri, L, Kandzari, DE, Leon, MB, and Cutlip, DE. "Long-term efficacy and safety of zotarolimus-eluting stent in patients with diabetes mellitus: Pooled 5-year results from the ENDEAVOR III and IV trials." Catheterization and Cardiovascular Interventions 82, no. 7 (December 1, 2013): 1031-1038. Full Text
  - Vardi, M, Burke, DA, Bangalore, S, Pencina, MJ, Mauri, L, Kandzari, DE, Leon, MB, and Cutlip, DE. "Long-term efficacy and safety of Zotarolimus-eluting stent in patients with diabetes mellitus: pooled 5-year results from the ENDEAVOR III and IV trials." Catheter Cardiovasc Interv 82, no. 7 (December 1, 2013): 1031-1038. Full Text Link to Item
  - Demler, OV, Pencina, MJ, and D'Agostino, RB. "Impact of correlation on predictive ability of biomarkers." Stat Med 32, no. 24 (October 30, 2013): 4196-4210. Full Text Link to Item
  - Nikolic, D, Banach, M, Nikfar, S, Salari, P, Mikhailidis, DP, Toth, PP, Abdollahi, M, Ray, KK, Pencina, MJ, Malyszko, J, Rysz, J, Rizzo, M, and Lipid and Blood Pressure Meta-Analysis Collaboration Group, . "A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important?." Int J Cardiol 168, no. 6 (October 15, 2013): 5437-5447. Full Text Link to Item
  - Nikolic, D, Banach, M, Nikfar, S, Salari, P, Mikhailidis, DP, Toth, PP, Abdollahi, M, Ray, KK, Pencina, MJ, Malyszko, J, Rysz, J, and Rizzo, M. "A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important?." International Journal of Cardiology 168, no. 6 (October 15, 2013): 5437-5447. Full Text
  - Banach, M, Nikfar, S, Rahimi, R, Bielecka-Dabrowa, A, Pencina, MJ, Mikhailidis, DP, Narkiewicz, K, Rysz, J, Ray, KK, Abdollahi, M, and Lipid and Blood Pressure Meta-Analysis Collaboration Group, . "The effects of statins on blood pressure in normotensive or hypertensive subjects--a meta-analysis of randomized controlled trials." International Journal of Cardiology 168, no. 3 (October 2013): 2816-2824. Full Text
  - Widera, C, Pencina, MJ, Bobadilla, M, Reimann, I, Guba-Quint, A, Marquardt, I, Bethmann, K, Korf-Klingebiel, M, Kempf, T, Lichtinghagen, R, Katus, HA, Giannitsis, E, and Wollert, KC. "Incremental prognostic value of biomarkers beyond the GRACE (Global Registry of Acute Coronary Events) score and high-sensitivity cardiac troponin T in non-ST-elevation acute coronary syndrome." Clin Chem 59, no. 10 (October 2013): 1497-1505. Full Text Link to Item
  - Lubitz, SA, Moser, C, Sullivan, L, Rienstra, M, Fontes, JD, Villalon, ML, Pai, M, McManus, DD, Schnabel, RB, Magnani, JW, Yin, X, Levy, D, Pencina, MJ, Larson, MG, Ellinor, PT, and Benjamin, EJ. "Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community." Journal of the American Heart Association 2, no. 5 (September 3, 2013): e000126-null. Full Text
  - Berry, SD, Samelson, EJ, Pencina, MJ, McLean, RR, Cupples, LA, Broe, KE, and Kiel, DP. "Repeat bone mineral density screening and prediction of hip and major osteoporotic fracture." Jama 310, no. 12 (September 2013): 1256-1262. Full Text
  - Califf, RM, and Pencina, MJ. "Predictive models in heart failure: who cares?." Circulation. Heart Failure 6, no. 5 (September 2013): 877-878. Full Text
  - Vickers, AJ, and Pencina, MJ. "Prostate-specific antigen velocity: new methods, same results, still no evidence of clinical utility." Eur Urol 64, no. 3 (September 2013): 394-396. Full Text Link to Item
  - Schnabel, RB, Rienstra, M, Sullivan, LM, Sun, JX, Moser, CB, Levy, D, Pencina, MJ, Fontes, JD, Magnani, JW, McManus, DD, Lubitz, SA, Tadros, TM, Wang, TJ, Ellinor, PT, Vasan, RS, and Benjamin, EJ. "Risk assessment for incident heart failure in individuals with atrial fibrillation." European Journal of Heart Failure 15, no. 8 (August 2013): 843-849. Full Text
  - Shah, R, Heydari, B, Coelho-Filho, O, Murthy, VL, Abbasi, S, Feng, JH, Pencina, M, Neilan, TG, Meadows, JL, Francis, S, Blankstein, R, Steigner, M, di Carli, M, Jerosch-Herold, M, and Kwong, RY. "Stress cardiac magnetic resonance imaging provides effective cardiac risk reclassification in patients with known or suspected stable coronary artery disease." Circulation 128, no. 6 (August 2013): 605-614. Full Text
  - Doros, G, Pencina, M, Rybin, D, Meisner, A, and Fava, M. "A repeated measures model for analysis of continuous outcomes in sequential parallel comparison design studies." Statistics in Medicine 32, no. 16 (July 2013): 2767-2789. Full Text
  - Barylski, M, Nikfar, S, Mikhailidis, DP, Toth, PP, Salari, P, Ray, KK, Pencina, MJ, Rizzo, M, Rysz, J, Abdollahi, M, Nicholls, SJ, Banach, M, and Lipid and Blood Pressure Meta-Analysis Collaboration Group, . "Statins decrease all-cause mortality only in CKD patients not requiring dialysis therapy--a meta-analysis of 11 randomized controlled trials involving 21,295 participants." Pharmacol Res 72 (June 2013): 35-44. Full Text Link to Item
  - Jasuja, GK, Travison, TG, Davda, M, Murabito, JM, Basaria, S, Zhang, A, Kushnir, MM, Rockwood, AL, Meikle, W, Pencina, MJ, Coviello, A, Rose, AJ, D'Agostino, R, Vasan, RS, and Bhasin, S. "Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 68, no. 6 (June 2013): 733-740. Full Text
  - Preis, SR, Pencina, MJ, Mann, DM, D'Agostino, RB, Savage, PJ, and Fox, CS. "Early-adulthood cardiovascular disease risk factor profiles among individuals with and without diabetes in the Framingham Heart Study." Diabetes Care 36, no. 6 (June 2013): 1590-1596. Full Text Link to Item
  - Lieb, W, Jansen, H, Loley, C, Pencina, MJ, Nelson, CP, Newton-Cheh, C, Kathiresan, S, Reilly, MP, Assimes, TL, Boerwinkle, E, Hall, AS, Hengstenberg, C, Laaksonen, R, McPherson, R, Thorsteinsdottir, U, Ziegler, A, Peters, A, Thompson, JR, König, IR, Erdmann, J, Samani, NJ, Vasan, RS, Schunkert, H, and CARDIoGRAM, . "Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension (Dallas, Tex. : 1979) 61, no. 5 (May 2013): 995-1001. Full Text
  - Nikolic, D, Nikfar, S, Salari, P, Rizzo, M, Ray, KK, Pencina, MJ, Mikhailidis, DP, Toth, PP, Nicholls, SJ, Rysz, J, Abdollahi, M, Banach, M, and Lipid and Blood Pressure Meta-Analysis Collaboration Group, . "Effects of statins on lipid profile in chronic kidney disease patients: a meta-analysis of randomized controlled trials." Curr Med Res Opin 29, no. 5 (May 2013): 435-451. (Review) Full Text Link to Item
  - Van Calster, B, Vickers, AJ, Pencina, MJ, Baker, SG, Timmerman, D, and Steyerberg, EW. "Evaluation of markers and risk prediction models: overview of relationships between NRI and decision-analytic measures." Medical Decision Making : an International Journal of the Society for Medical Decision Making 33, no. 4 (May 2013): 490-501. (Review) Full Text
  - de Miguel-Yanes, JM, Porneala, B, Pencina, MJ, Fox, CS, Florez, JC, Siscovick, DS, Dupuis, J, and Meigs, JB. "Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study." Journal of Hypertension 31, no. 5 (May 2013): 1001-1009. Full Text
  - Pencina, MJ, D'Agostino, RB, and Massaro, JM. "Understanding increments in model performance metrics." Lifetime Data Anal 19, no. 2 (April 2013): 202-218. Full Text Link to Item
  - Alonso, A, Krijthe, BP, Aspelund, T, Stepas, KA, Pencina, MJ, Moser, CB, Sinner, MF, Sotoodehnia, N, Fontes, JD, Janssens, ACJW, Kronmal, RA, Magnani, JW, Witteman, JC, Chamberlain, AM, Lubitz, SA, Schnabel, RB, Agarwal, SK, McManus, DD, Ellinor, PT, Larson, MG, Burke, GL, Launer, LJ, Hofman, A, Levy, D, Gottdiener, JS, Kääb, S, Couper, D, Harris, TB, Soliman, EZ, Stricker, BHC, Gudnason, V, Heckbert, SR, and Benjamin, EJ. "Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium." Journal of the American Heart Association 2, no. 2 (March 18, 2013): e000102-null. Full Text
  - Boggs, DA, Rosenberg, L, Pencina, MJ, Adams-Campbell, LL, and Palmer, JR. "Validation of a breast cancer risk prediction model developed for Black women." J Natl Cancer Inst 105, no. 5 (March 6, 2013): 361-367. Full Text Link to Item
  - Clair, C, Rigotti, NA, Porneala, B, Fox, CS, D'Agostino, RB, Pencina, MJ, and Meigs, JB. "Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes." Jama 309, no. 10 (March 2013): 1014-1021. Full Text
  - D'Agostino, RB, Pencina, MJ, Massaro, JM, and Coady, S. "Cardiovascular Disease Risk Assessment: Insights from Framingham." Global Heart 8, no. 1 (March 2013): 11-23. Full Text
  - Matthan, NR, Zhu, L, Pencina, M, D'Agostino, RB, Schaefer, EJ, and Lichtenstein, AH. "Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants." Journal of the American Heart Association 2, no. 1 (February 19, 2013): e005066-null. Full Text
  - Banach, M, Nikfar, S, Rahimi, R, Bielecka-Dabrowa, A, Pencina, MJ, Mikhailidis, DP, Narkiewicz, K, Rysz, J, Ray, KK, and Abdollahi, M. "The effects of statins on blood pressure in normotensive or hypertensive subjects - A meta-analysis of randomized controlled trials." International Journal of Cardiology 168, no. 3 (2013): 2816-2824. Full Text
  - Bangalore, S, Pencina, MJ, Kleiman, NS, and Cohen, DJ. "Prognostic implications of procedural vs spontaneous myocardial infarction: Results from the Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry." American Heart Journal (2013).
  - Bouchard, DR, Porneala, B, Janssen, I, Langlois, M-F, Baillargeon, J-P, Fox, CS, Meigs, JB, Sr, RBD, Pencina, M, and Hivert, M-F. "Risk of type 2 diabetes and cumulative excess weight exposure in the Framingham Offspring Study." Journal of Diabetes and its Complications 27, no. 3 (2013): 214-218. Full Text
  - Costa, MA, Pencina, M, Nikolic, S, Engels, T, Templin, B, and Abraham, WT. "The PARACHUTE IV trial design and rationale: Percutaneous ventricular restoration using the parachute device in patients with ischemic heart failure and dilated left ventricles." American Heart Journal 165, no. 4 (2013): 531-536. Full Text
  - Demler, OV, Pencina, MJ, and D'Agostino, RB. "Impact of correlation on predictive ability of biomarkers." Statistics in Medicine 32, no. 24 (2013): 4196-4210. Full Text
  - Dorbala, S, Di Carli, MF, Beanlands, RS, Merhige, ME, Williams, BA, Veledar, E, Chow, BJW, Min, JK, Pencina, MJ, Berman, DS, and Shaw, LJ. "Prognostic value of stress myocardial perfusion positron emission tomography: results from a multicenter observational registry." Journal of the American College of Cardiology 61, no. 2 (January 2013): 176-184. Full Text
  - Dording, C, Cassiello, C, IV, FK, Pencina, M, Fava, M, and Mischoulon, D. "The effects of aripiprazole on the subscales of the Kellner Symptom Questionnaire in treatment resistant depression." International Clinical Psychopharmacology 28, no. 5 (2013): 238-244. Full Text
  - Fatemi, O, Paranilam, J, Rainow, A, Kennedy, K, Choi, J, Cutlip, D, Pencina, M, Berger, PB, Cohen, DJ, and Kleiman, NS. "Red cell distribution width is a predictor of mortality in patients undergoing percutaneous coronary intervention." Journal of Thrombosis and Thrombolysis 35, no. 1 (January 2013): 57-64. Full Text
  - Kemp, DE, Sylvia, LG, Calabrese, JR, Nierenberg, AA, Thase, ME, Reilly-Harrington, NA, Ostacher, MJ, Leon, AC, Ketter, TA, Friedman, ES, and al, E. "General medical burden in bipolar disorder: Findings from the LiTMUS comparative effectiveness trial." Acta Psychiatrica Scandinavica (2013). Full Text
  - Menon, S, Massaro, J, Pencina, MJ, Lewis, J, and Wang, YC. "Comparison of Operating Characteristics of Commonly Used Sample Size Re-Estimation Procedures in a Two-Stage Design." Communications in Statistics - Simulation and Computation 42 (2013): 1140-1152. Full Text
  - Mihaescu, R, Pencina, MJ, Alonso, A, Lunetta, KL, Heckbert, SR, Benjamin, EJ, and Janssens, ACJW. "Incremental value of rare genetic variants for the prediction of multifactorial diseases. (Published online)" Genome Med 5, no. 8 (2013): 76-. Full Text Link to Item
  - Nierenberg, AA, Friedman, ES, Bowden, CL, Sylvia, LG, Thase, ME, Ketter, T, Ostacher, MJ, Leon, AC, Reilly-Harrington, N, Iosifescu, DV, Pencina, M, Severe, JB, and Calabrese, JR. "Lithium treatment moderate-dose use study (LiTMUS) for bipolar disorder: A randomized comparative effectiveness trial of optimized personalized treatment with and without lithium." American Journal of Psychiatry 170, no. 1 (2013): 102-110. Full Text
  - Preis, SR, Pencina, MJ, D'Agostino, RB, Meigs, JB, Vasan, RS, and Fox, CS. "Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study." Diabetes Care 36, no. 1 (January 2013): e3-null. (Letter) Full Text
  - Singh, GM, Danaei, G, Farzadfar, F, Stevens, GA, Woodward, M, Wormser, D, Kaptoge, S, Whitlock, G, Qiao, Q, Lewington, S, Di Angelantonio, E, Vander Hoorn, S, Lawes, CMM, Ali, MK, Mozaffarian, D, Ezzati, M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group, Asia-Pacific Cohort Studies Collaboration (APCSC), , Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe (DECODE), , Emerging Risk Factor Collaboration (ERFC), , and Prospective Studies Collaboration (PSC), . "The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis." Plos One 8, no. 7 (January 2013): e65174-null. Full Text
  - Sinner, MF, Wang, N, Fox, CS, Fontes, JD, Rienstra, M, Magnani, JW, Vasan, RS, Calderwood, AH, Pencina, M, Sullivan, LM, Ellinor, PT, and Benjamin, EJ. "Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation." The American Journal of Cardiology 111, no. 2 (January 2013): 219-224. Full Text
  - Zdrojewski, T, Rutkowski, M, Bandosz, P, Gaciong, Z, Jedrzejczyk, T, Solnica, B, Pencina, M, Drygas, W, Wojtyniak, B, Grodzicki, T, Piwoński, J, and Wyrzykowski, B. "Prevalence and control of cardiovascular risk factors in Poland. Assumptions and objectives of the NATPOL 2011 Survey." Kardiologia Polska 71, no. 4 (2013): 381-392. Full Text
  - Steyerberg, EW, Pencina, MJ, and Van Calster, B. "[Discriminative ability, reclassification and net benefit: the predictive value of biomarkers]." Nederlands tijdschrift voor geneeskunde 156, no. 41 (December 1, 2012). (Review)
  - Stolker, JM, Cohen, DJ, Kennedy, KF, Pencina, MJ, Lindsey, JB, Mauri, L, Cutlip, DE, Kleiman, NS, and Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) Investigators, . "Repeat revascularization after contemporary percutaneous coronary intervention: an evaluation of staged, target lesion, and other unplanned revascularization procedures during the first year." Circ Cardiovasc Interv 5, no. 6 (December 2012): 772-782. Full Text Link to Item
  - Sun, H, Davison, BA, Cotter, G, Pencina, MJ, and Koch, GG. "Evaluating treatment efficacy by multiple end points in phase II acute heart failure clinical trials: analyzing data using a global method." Circulation. Heart Failure 5, no. 6 (November 2012): 742-749. Full Text
  - Vassy, JL, Dasmahapatra, P, Meigs, JB, Schork, NJ, Magnussen, CG, Chen, W, Raitakari, OT, Pencina, MJ, Jamal, SM, Berenson, GS, and Goodman, E. "Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population." Pediatrics 130, no. 5 (November 2012): e1235-e1242. Full Text Link to Item
  - "Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis." International Journal of Epidemiology 41, no. 5 (October 2012): 1419-1433. Full Text
  - Demler, OV, Pencina, MJ, and D'Agostino, RB. "Misuse of DeLong test to compare AUCs for nested models." Statistics in Medicine 31, no. 23 (October 2012): 2577-2587. Full Text
  - Ho, JE, Liu, C, Lyass, A, Courchesne, P, Pencina, MJ, Vasan, RS, Larson, MG, and Levy, D. "Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community." Journal of the American College of Cardiology 60, no. 14 (October 2012): 1249-1256. Full Text
  - Steyerberg, EW, Pencina, MJ, and Van Calster, B. "Discriminative ability, reclassification and net benefit: Research methodology No. 7: The predictive value of biomarkers." Nederlands Tijdschrift voor Geneeskunde 156, no. 43 (October 1, 2012).
  - Min, JK, Leipsic, J, Pencina, MJ, Berman, DS, Koo, B-K, van Mieghem, C, Erglis, A, Lin, FY, Dunning, AM, Apruzzese, P, Budoff, MJ, Cole, JH, Jaffer, FA, Leon, MB, Malpeso, J, Mancini, GBJ, Park, S-J, Schwartz, RS, Shaw, LJ, and Mauri, L. "Diagnostic accuracy of fractional flow reserve from anatomic CT angiography." Jama 308, no. 12 (September 2012): 1237-1245. Full Text
  - Pencina, MJ, D'Agostino, RB, Demler, OV, Janssens, ACJW, and Greenland, P. "Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution"." American Journal of Epidemiology 176, no. 6 (September 2012): 492-494. Full Text
  - Pencina, MJ, D'Agostino, RB, Pencina, KM, Janssens, ACJW, and Greenland, P. "Interpreting incremental value of markers added to risk prediction models." American Journal of Epidemiology 176, no. 6 (September 2012): 473-481. Full Text
  - Polak, JF, Meisner, A, Pencina, MJ, Wolf, PA, and D'Agostino, RB. "Variations in common carotid artery intima-media thickness during the cardiac cycle: implications for cardiovascular risk assessment." J Am Soc Echocardiogr 25, no. 9 (September 2012): 1023-1028. Full Text Link to Item
  - Brautbar, A, Pompeii, LA, Dehghan, A, Ngwa, JS, Nambi, V, Virani, SS, Rivadeneira, F, Uitterlinden, AG, Hofman, A, Witteman, JCM, Pencina, MJ, Folsom, AR, Cupples, LA, Ballantyne, CM, and Boerwinkle, E. "A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies." Atherosclerosis 223, no. 2 (August 2012): 421-426. Full Text
  - D'Agostino, RB, and Pencina, MJ. "Invited commentary: Clinical usefulness of the Framingham cardiovascular risk profile beyond its statistical performance." Am J Epidemiol 176, no. 3 (August 1, 2012): 187-189. Full Text Link to Item
  - Pencina, MJ. "Caution is needed in the interpretation of added value of biomarkers analyzed in matched case control studies." Clinical Chemistry 58, no. 8 (August 2012): 1176-1178. Full Text
  - Cho, I, Chang, H-J, Sung, JM, Pencina, MJ, Lin, FY, Dunning, AM, Achenbach, S, Al-Mallah, M, Berman, DS, Budoff, MJ, Callister, TQ, Chow, BJW, Delago, A, Hadamitzky, M, Hausleiter, J, Maffei, E, Cademartiri, F, Kaufmann, P, Shaw, LJ, Raff, GL, Chinnaiyan, KM, Villines, TC, Cheng, V, Nasir, K, Gomez, M, Min, JK, and CONFIRM Investigators, . "Coronary computed tomographic angiography and risk of all-cause mortality and nonfatal myocardial infarction in subjects without chest pain syndrome from the CONFIRM Registry (coronary CT angiography evaluation for clinical outcomes: an international multicenter registry)." Circulation 126, no. 3 (July 2012): 304-313. Full Text
  - Ho, JE, Gona, P, Pencina, MJ, Tu, JV, Austin, PC, Vasan, RS, Kannel, WB, D'Agostino, RB, Lee, DS, and Levy, D. "Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community." European Heart Journal 33, no. 14 (July 2012): 1734-1741. Full Text
  - Pencina, MJ, D'Agostino, RB, and Song, L. "Quantifying discrimination of Framingham risk functions with different survival C statistics." Statistics in Medicine 31, no. 15 (July 2012): 1543-1553. Full Text
  - Wilson, PWF, D'Agostino, R, Bhatt, DL, Eagle, K, Pencina, MJ, Smith, SC, Alberts, MJ, Dallongeville, J, Goto, S, Hirsch, AT, Liau, C-S, Ohman, EM, Röther, J, Reid, C, Mas, J-L, Steg, PG, and REACH Registry, . "An international model to predict recurrent cardiovascular disease." The American Journal of Medicine 125, no. 7 (July 2012): 695-703.e1. Full Text
  - Rana, JS, Gransar, H, Wong, ND, Shaw, L, Pencina, M, Nasir, K, Rozanski, A, Hayes, SW, Thomson, LE, Friedman, JD, Min, JK, and Berman, DS. "Comparative value of coronary artery calcium and multiple blood biomarkers for prognostication of cardiovascular events." The American Journal of Cardiology 109, no. 10 (May 2012): 1449-1453. Full Text
  - Widera, C, Pencina, MJ, Meisner, A, Kempf, T, Bethmann, K, Marquardt, I, Katus, HA, Giannitsis, E, and Wollert, KC. "Adjustment of the GRACE score by growth differentiation factor 15 enables a more accurate appreciation of risk in non-ST-elevation acute coronary syndrome." European Heart Journal 33, no. 9 (May 2012): 1095-1104. Full Text
  - Pencina, MJ, and D'Agostino, RB. "Thoroughly modern risk prediction?." Sci Transl Med 4, no. 131 (April 25, 2012): 131fs10-. Full Text Link to Item
  - Mischoulon, D, Witte, J, Levy, M, Papakostas, GI, Pet, LR, Hsieh, W-H, Pencina, MJ, Ward, S, Pollack, MH, and Fava, M. "Efficacy of dose increase among nonresponders to low-dose aripiprazole augmentation in patients with inadequate response to antidepressant treatment: a randomized, double-blind, placebo-controlled, efficacy trial." J Clin Psychiatry 73, no. 3 (March 2012): 353-357. Full Text Link to Item
  - Prushik, SG, Farber, A, Gona, P, Shrader, P, Pencina, MJ, D'Agostino, RB, and Murabito, JM. "Parental intermittent claudication as risk factor for claudication in adults." Am J Cardiol 109, no. 5 (March 1, 2012): 736-741. Full Text Link to Item
  - Dording, CM, Dalton, ED, Pencina, MJ, Fava, M, and Mischoulon, D. "Comparison of academic and nonacademic sites in multi-center clinical trials." J Clin Psychopharmacol 32, no. 1 (February 2012): 65-68. Full Text Link to Item
  - Steyerberg, EW, Pencina, MJ, Lingsma, HF, Kattan, MW, Vickers, AJ, and Van Calster, B. "Assessing the incremental value of diagnostic and prognostic markers: a review and illustration." European Journal of Clinical Investigation 42, no. 2 (February 2012): 216-228. Full Text
  - Thanassoulis, G, Peloso, GM, Pencina, MJ, Hoffmann, U, Fox, CS, Cupples, LA, Levy, D, D'Agostino, RB, Hwang, S-J, and O'Donnell, CJ. "A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study." Circulation. Cardiovascular Genetics 5, no. 1 (February 2012): 113-121. Full Text
  - Pencina, MJ, Sr, DRB, and Steyerberg, EW. "Comments on Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers' by M. J. Pencina, R. B. D'Agostino, Sr. and E. W. Steyerberg reply." STATISTICS IN MEDICINE 31, no. 1 (January 13, 2012): 96-97. Full Text Link to Item
  - Caputo, RP, Goel, A, Pencina, M, Cohen, DJ, Kleiman, NS, Yen, C-H, Waksman, R, Tolerico, P, Dhar, G, Gordon, P, Bach, RG, and Lopez, JJ. "Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry)." American Journal of Cardiology 110, no. 3 (2012): 350-355. Full Text
  - Fava, M, Mischoulon, D, Iosifescu, D, Witte, J, Pencina, M, Flynn, M, Harper, L, Levy, M, Rickels, K, and Pollack, M. "A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A study):(Psychotherapy and Psychosomatics (2012) 81, (87-97))." Psychotherapy and Psychosomatics 81, no. 4 (2012): 261--. Full Text
  - Fava, M, Mischoulon, D, Iosifescu, D, Witte, J, Pencina, M, Flynn, M, Harper, L, Levy, M, Rickels, K, and Pollack, M. "A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A Study)." Psychotherapy and Psychosomatics 81, no. 2 (2012): 87-97. Full Text
  - Murphy, TP, Dhangana, R, Pencina, MJ, and D'Agostino, RB. "Ankle-brachial index and cardiovascular risk prediction: an analysis of 11,594 individuals with 10-year follow-up." Atherosclerosis 220, no. 1 (January 2012): 160-167. Full Text
  - Novack, V, Pencina, M, Cohen, DJ, Kleiman, NS, Yen, C-H, Saucedo, JF, Berger, PB, and Cutlip, DE. "Troponin criteria for myocardial infarction after percutaneous coronary intervention." Archives of Internal Medicine 172, no. 6 (2012): 502-508. Full Text
  - Papakostas, GI, Shelton, RC, Zajecka, JM, Etemad, B, Rickels, K, Clain, A, Baer, L, Dalton, ED, Sacco, GR, Schoenfeld, D, Pencina, M, Meisner, A, Bottiglieri, T, Nelson, E, Mischoulon, D, Alpert, JE, Barbee, JG, Zisook, S, and Fava, M. "L-methylfolate as adjunctive therapy for SSRI-resistant major depression: Results of two randomized, double-blind,parallel-sequential trials." American Journal of Psychiatry 169, no. 12 (2012): 1267-1274. Full Text
  - Pencina, MJ, D'Agostino, RB, and Demler, OV. "Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models." Statistics in Medicine 31, no. 2 (January 2012): 101-113. Full Text
  - Polak, JF, and Pencina, MJ. "Measuring carotid artery intima-media thickness: simplicity versus complexity?." J Am Soc Echocardiogr 25, no. 1 (January 2012): 101-104. Full Text Link to Item
  - Rapsomaniki, E, White, IR, Wood, AM, Thompson, SG, and Emerging Risk Factors Collaboration, . "A framework for quantifying net benefits of alternative prognostic models." Statistics in Medicine 31, no. 2 (January 2012): 114-130. Full Text
  - Steyerberg, EW, Pencina, MJ, and Calster, BV. "Discriminative ability, reclassification and net benefit: Research methodology No. 7: The predictive value of biomarkers." Nederlands Tijdschrift voor Geneeskunde 156, no. 43 (2012).
  - Steyerberg, EW, Pencina, MJ, and Van Calster, B. "[Discriminative ability, reclassification and net benefit: the predictive value of biomarkers]." Ned Tijdschr Geneeskd 156, no. 41 (2012): A5029-. (Review) Link to Item
  - Mega, JL, Hochholzer, W, Frelinger, AL, Kluk, MJ, Angiolillo, DJ, Kereiakes, DJ, Isserman, S, Rogers, WJ, Ruff, CT, Contant, C, Pencina, MJ, Scirica, BM, Longtine, JA, Michelson, AD, and Sabatine, MS. "Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease." Jama 306, no. 20 (November 16, 2011): 2221-2228. Full Text
  - Bhasin, S, Jasjua, GK, Pencina, M, D'Agostino, R, Coviello, AD, Vasan, RS, and Travison, TG. "Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study." Diabetes Care 34, no. 11 (November 2011): 2464-2470. Full Text
  - Murthy, VL, Naya, M, Foster, CR, Hainer, J, Gaber, M, Di Carli, G, Blankstein, R, Dorbala, S, Sitek, A, Pencina, MJ, and Di Carli, MF. "Improved cardiac risk assessment with noninvasive measures of coronary flow reserve." Circulation 124, no. 20 (November 2011): 2215-2224. Full Text
  - Polak, JF, Pencina, MJ, O'Leary, DH, and D'Agostino, RB. "Common carotid artery intima-media thickness progression as a predictor of stroke in multi-ethnic study of atherosclerosis." Stroke 42, no. 11 (November 2011): 3017-3021. Full Text
  - Lindsey, JB, Kennedy, KF, Stolker, JM, Gilchrist, IC, Mukherjee, D, Marso, SP, Pencina, MJ, Kleiman, NS, and Cohen, DJ. "Prognostic implications of creatine kinase-MB elevation after percutaneous coronary intervention: results from the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry." Circulation. Cardiovascular Interventions 4, no. 5 (October 4, 2011): 474-480. Full Text
  - Janssens, ACJW, Ioannidis, JPA, Bedrosian, S, Boffetta, P, Dolan, SM, Dowling, N, Fortier, I, Freedman, AN, Grimshaw, JM, Gulcher, J, Gwinn, M, Hlatky, MA, Janes, H, Kraft, P, Melillo, S, O'Donnell, CJ, Pencina, MJ, Ransohoff, D, Schully, SD, Seminara, D, Winn, DM, Wright, CF, van Duijn, CM, Little, J, and Khoury, MJ. "Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration." European Journal of Clinical Investigation 41, no. 9 (September 2011): 1010-1035. Full Text
  - Steyerberg, EW, Van Calster, B, and Pencina, MJ. "[Performance measures for prediction models and markers: evaluation of predictions and classifications]." Revista Espanola De Cardiologia 64, no. 9 (September 2011): 788-794. Full Text
  - Steyerberg, EW, Van Calster, B, and Pencina, MJ. "Performance measures for prediction models and markers: Evaluation of predictions and classifications." Revista Espanola De Cardiologia 64, no. 9 (September 1, 2011): 788-794. Full Text
  - Venkitachalam, L, Lei, Y, Stolker, JM, Mahoney, EM, Amin, AP, Lindsey, JB, Kennedy, KF, Pencina, MJ, Lopez, JJ, Kleiman, NS, Cohen, DJ, and EVENT Registry Investigators, . "Clinical and economic outcomes of liberal versus selective drug-eluting stent use: insights from temporal analysis of the multicenter Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry." Circulation 124, no. 9 (August 30, 2011): 1028-1037. Full Text Link to Item
  - Janssens, ACJW, Ioannidis, JPA, Bedrosian, S, Boffetta, P, Dolan, SM, Dowling, N, Fortier, I, Freedman, AN, Grimshaw, JM, Gulcher, J, Gwinn, M, Hlatky, MA, Janes, H, Kraft, P, Melillo, S, O'Donnell, CJ, Pencina, MJ, Ransohoff, D, Schully, SD, Seminara, D, Winn, DM, Wright, CF, van Duijn, CM, Little, J, and Khoury, MJ. "Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration." J Clin Epidemiol 64, no. 8 (August 2011): e1-e22. Full Text Link to Item
  - Lieb, W, Pencina, MJ, Jacques, PF, Wang, TJ, Larson, MG, Levy, D, Kannel, WB, and Vasan, RS. "Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community." European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 18, no. 4 (August 2011): 664-673. Full Text
  - Polak, JF, Pencina, MJ, Herrington, D, and O'Leary, DH. "Associations of edge-detected and manual-traced common carotid intima-media thickness measurements with Framingham risk factors: the multi-ethnic study of atherosclerosis." Stroke 42, no. 7 (July 2011): 1912-1916. Full Text
  - Polak, JF, Pencina, MJ, Pencina, KM, O'Donnell, CJ, Wolf, PA, and D'Agostino, RB. "Carotid-wall intima-media thickness and cardiovascular events." The New England Journal of Medicine 365, no. 3 (July 2011): 213-221. Full Text
  - Murphy, TP, Dhangana, R, Pencina, MJ, Zafar, AM, and D'Agostino, RB. "Performance of current guidelines for coronary heart disease prevention: optimal use of the Framingham-based risk assessment." Atherosclerosis 216, no. 2 (June 2011): 452-457. Full Text Link to Item
  - Demler, OV, Pencina, MJ, and D'Agostino, RB. "Equivalence of improvement in area under ROC curve and linear discriminant analysis coefficient under assumption of normality." Stat Med 30, no. 12 (May 30, 2011): 1410-1418. Full Text Link to Item
  - Dhangana, R, Murphy, TP, Pencina, MJ, and Zafar, AM. "Prevalence of low ankle-brachial index, elevated plasma fibrinogen and CRP across Framingham risk categories: data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004." Atherosclerosis 216, no. 1 (May 2011): 174-179. Full Text Link to Item
  - Janssens, ACJW, Ioannidis, JPA, Bedrosian, S, Boffetta, P, Dolan, SM, Dowling, N, Fortier, I, Freedman, AN, Grimshaw, JM, Gulcher, J, Gwinn, M, Hlatky, MA, Janes, H, Kraft, P, Melillo, S, O'Donnell, CJ, Pencina, MJ, Ransohoff, D, Schully, SD, Seminara, D, Winn, DM, Wright, CF, van Duijn, CM, Little, J, and Khoury, MJ. "Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration." European Journal of Human Genetics : Ejhg 19, no. 5 (May 2011): 18 p preceding 494-null. Full Text
  - Uno, H, Cai, T, Pencina, MJ, D'Agostino, RB, and Wei, LJ. "On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data." Statistics in Medicine 30, no. 10 (May 2011): 1105-1117. Full Text
  - Zachariah, JP, Pencina, MJ, Lyass, A, Kaur, G, D'Agostino, RB, Ordovas, JM, and Vasan, RS. "Circulating plasma cholesteryl ester transfer protein activity and blood pressure tracking in the community." Journal of Hypertension 29, no. 5 (May 2011): 863-868. Full Text
  - Janssens, ACJW, Ioannidis, JPA, Bedrosian, S, Boffetta, P, Dolan, SM, Dowling, N, Fortier, I, Freedman, AN, Grimshaw, JM, Gulcher, J, Gwinn, M, Hlatky, MA, Janes, H, Kraft, P, Melillo, S, O'Donnell, CJ, Pencina, MJ, Ransohoff, D, Schully, SD, Seminara, D, Winn, DM, Wright, CF, van Duijn, CM, Little, J, and Khoury, MJ. "Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration." European Journal of Epidemiology 26, no. 4 (April 2011): 313-337. Full Text
  - Dietrich, M, Jacques, PF, Polak, JF, Keyes, MJ, Pencina, MJ, Evans, JC, Wolf, PA, Selhub, J, Vasan, RS, and D'Agostino, RB. "Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study." Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association 20, no. 2 (March 2011): 155-161. Full Text
  - Min, JK, Dunning, A, Lin, FY, Achenbach, S, Al-Mallah, MH, Berman, DS, Budoff, MJ, Cademartiri, F, Callister, TQ, Chang, H-J, Cheng, V, Chinnaiyan, KM, Chow, B, Delago, A, Hadamitzky, M, Hausleiter, J, Karlsberg, RP, Kaufmann, P, Maffei, E, Nasir, K, Pencina, MJ, Raff, GL, Shaw, LJ, and Villines, TC. "Rationale and design of the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) Registry." Journal of Cardiovascular Computed Tomography 5, no. 2 (March 2011): 84-92. Full Text
  - The Emerging Risk Factors Collaboration, . "Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies." The Lancet 377, no. 9771 (March 2011): 1085-1095. Full Text
  - Amin, AP, Kennedy, KF, Pencina, M, Berger, P, Piana, RN, Lopez, J, Kleiman, N, and Cohen, DJ. "Effect of clopidogrel pretreatment on ischemic complications of percutaneous coronary intervention among bivalirudin-treated patients (from the EVENT registry)." American Journal of Cardiology 107, no. 12 (2011): 1751-1756. Full Text
  - Bangalore, S, Cohen, DJ, Kleiman, NS, Regev-Beinart, T, Rao, SV, Pencina, MJ, and Mauri, L. "Bleeding risk comparing targeted low-dose heparin with bivalirudin in patients undergoing percutaneous coronary intervention: Results from a propensity score-matched analysis of the evaluation of drug-eluting stents and ischemic events (EVENT) registry." Circulation: Cardiovascular Interventions 4, no. 5 (2011): 463-473. Full Text
  - Bhasin, S, Pencina, M, Jasuja, GK, Travison, TG, Coviello, A, Orwoll, E, Wang, PY, Nielson, C, Wu, F, Tajar, A, Labrie, F, Vesper, H, Zhang, A, Ulloor, J, Singh, R, D'Agostino, R, and Vasan, RS. "Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the framingham heart study and applied to three geographically distinct cohorts." Journal of Clinical Endocrinology and Metabolism 96, no. 8 (2011): 2430-2439. Full Text
  - Brilakis, ES, Cohen, DJ, Kleiman, NS, Pencina, M, Nassif, D, Saucedo, J, Piana, RN, Banerjee, S, Keyes, MJ, Yen, C-H, and Berger, PB. "Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: Results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry." American Heart Journal 161, no. 2 (2011): 360-366. Full Text
  - Janssens, ACJW, Ioannidis, JPA, Bedrosian, S, Boffetta, P, Dolan, SM, Dowling, N, Fortier, I, Freedman, AN, Grimshaw, JM, Gulcher, J, Gwinn, M, Hlatky, MA, Janes, H, Kraft, P, Melillo, S, O'Donnell, CJ, Pencina, MJ, Ransohoff, D, Schully, SD, Seminara, D, Winn, DM, Wright, CF, Duijn, CMV, Little, J, and Khoury, MJ. "Strengthening the reporting of genetic risk prediction studies (GRIPS): Explanation and elaboration." European Journal of Human Genetics 19, no. 5 (2011): 493--. Full Text
  - Mauri, L, Normand, S-LT, Pencina, M, Cutlip, DE, Jeon, C, Dreyer, P, Kuntz, RE, Baim, DS, and Jacobs, AK. "Rationale and design of the MASS COMM trial: A randomized trial to compare percutaneous coronary intervention between MASSachusetts hospitals with cardiac surgery on-site and COMMunity hospitals without cardiac surgery on-site." American Heart Journal 162, no. 5 (2011): 826-831. Full Text
  - Menon, S, Massaro, J, Lewis, J, Pencina, M, Wang, Y-C, and Lavin, P. "Sample size calculation for poisson endpoint using the exact distribution of difference between two poisson random variables." Statistics in Biopharmaceutical Research 3, no. 3 (2011): 497-504. Full Text
  - Pencina, MJ, D'Agostino, RB, and Steyerberg, EW. "Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers." Statistics in Medicine 30, no. 1 (January 2011): 11-21. Full Text
  - Polak, JF, Pencina, MJ, and Sr, RBD. "The authors reply." New England Journal of Medicine 365, no. 17 (2011): 1641-1642.
  - Rocha-Singh, KJ, Novack, V, Pencina, M, D'Agostino, R, Ansel, G, Rosenfield, K, and Jaff, MR. "Objective performance goals of safety and blood pressure efficacy for clinical trials of renal artery bare metal stents in hypertensive patients with atherosclerotic renal artery stenosis." Catheterization and Cardiovascular Interventions 78, no. 5 (2011): 779-789. Full Text
  - de Miguel-Yanes, JM, Shrader, P, Pencina, MJ, Fox, CS, Manning, AK, Grant, RW, Dupuis, J, Florez, JC, D'Agostino, RB, Cupples, LA, Meigs, JB, MAGIC Investigators, , and DIAGRAM+ Investigators, . "Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms." Diabetes Care 34, no. 1 (January 2011): 121-125. Full Text
  - Lam, CSP, Liu, X, Yang, Q, Larson, MG, Pencina, MJ, Aragam, J, Redfield, MM, Benjamin, EJ, and Vasan, RS. "Familial aggregation of left ventricular geometry and association with parental heart failure: the Framingham Heart Study." Circulation. Cardiovascular Genetics 3, no. 6 (December 2010): 492-498. Full Text
  - Pencina, MJ, D'Agostino, RB, and Vasan, RS. "Statistical methods for assessment of added usefulness of new biomarkers." Clinical Chemistry and Laboratory Medicine 48, no. 12 (December 2010): 1703-1711. (Review) Full Text
  - Polak, JF, Pencina, MJ, Meisner, A, Pencina, KM, Brown, LS, Wolf, PA, and D'Agostino, RB. "Associations of carotid artery intima-media thickness (IMT) with risk factors and prevalent cardiovascular disease: comparison of mean common carotid artery IMT with maximum internal carotid artery IMT." Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine 29, no. 12 (December 2010): 1759-1768. Full Text
  - Lubitz, SA, Yin, X, Fontes, JD, Magnani, JW, Rienstra, M, Pai, M, Villalon, ML, Vasan, RS, Pencina, MJ, Levy, D, Larson, MG, Ellinor, PT, and Benjamin, EJ. "Association between familial atrial fibrillation and risk of new-onset atrial fibrillation." Jama 304, no. 20 (November 13, 2010): 2263-2269. Full Text
  - Mitchell, GF, Hwang, S-J, Vasan, RS, Larson, MG, Levy, D, Benjamin, EJ, Pencina, MJ, Hamburg, NM, and Vita, JA. "Response to Letters Regarding Article, "Arterial Stiffness and Cardiovascular Events: The Framingham Heart Study"." CIRCULATION 122, no. 19 (November 9, 2010): E515-E515. Full Text Link to Item
  - Schnabel, RB, Aspelund, T, Li, G, Sullivan, LM, Suchy-Dicey, A, Harris, TB, Pencina, MJ, D'Agostino, RB, Levy, D, Kannel, WB, Wang, TJ, Kronmal, RA, Wolf, PA, Burke, GL, Launer, LJ, Vasan, RS, Psaty, BM, Benjamin, EJ, Gudnason, V, and Heckbert, SR. "Validation of an atrial fibrillation risk algorithm in whites and African Americans." Archives of Internal Medicine 170, no. 21 (November 2010): 1909-1917. Full Text
  - Thompson, S, Kaptoge, S, White, I, Wood, A, Perry, P, and Danesh, J. "Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies." International Journal of Epidemiology 39, no. 5 (October 2010): 1345-1359. Full Text
  - Berger, PB, Kleiman, NS, Pencina, MJ, Hsieh, W-H, Steinhubl, SR, Jeremias, A, Sonel, A, Browne, K, Barseness, G, Cohen, DJ, and EVENT Investigators, . "Frequency of major noncardiac surgery and subsequent adverse events in the year after drug-eluting stent placement results from the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry." Jacc. Cardiovascular Interventions 3, no. 9 (September 2010): 920-927. Full Text
  - Vasan, RS, Pencina, MJ, Robins, SJ, D'Agostino, RB, Kaur, G, Zachariah, JP, and Ordovas, JM. "Response to Letter Regarding Article, "Association of Circulating Cholesteryl Ester Transfer Protein Activity With Incidence of Cardiovascular Disease in the Community"." CIRCULATION 122, no. 6 (August 10, 2010): E421-E421. Full Text Link to Item
  - Stolker, JM, Kennedy, KF, Lindsey, JB, Marso, SP, Pencina, MJ, Cutlip, DE, Mauri, L, Kleiman, NS, Cohen, DJ, and EVENT Investigators, . "Predicting restenosis of drug-eluting stents placed in real-world clinical practice: derivation and validation of a risk model from the EVENT registry." Circulation. Cardiovascular Interventions 3, no. 4 (August 2010): 327-334. Full Text
  - Kimokoti, RW, Newby, PK, Gona, P, Zhu, L, Jasuja, GK, Pencina, MJ, McKeon-O'Malley, C, Fox, CS, D'Agostino, RB, and Millen, BE. "Diet quality, physical activity, smoking status, and weight fluctuation are associated with weight change in women and men." J Nutr 140, no. 7 (July 2010): 1287-1293. Full Text Link to Item
  - Krasnoff, JB, Basaria, S, Pencina, MJ, Jasuja, GK, Vasan, RS, Ulloor, J, Zhang, A, Coviello, A, Kelly-Hayes, M, D'Agostino, RB, Wolf, PA, Bhasin, S, and Murabito, JM. "Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study." The Journal of Clinical Endocrinology and Metabolism 95, no. 6 (June 2010): 2790-2799. Full Text
  - The Emerging Risk Factors Collaboration, . "Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies." The Lancet 375, no. 9733 (June 2010): 2215-2222. Full Text
  - Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, , Sarwar, N, Sandhu, MS, Ricketts, SL, Butterworth, AS, Di Angelantonio, E, Boekholdt, SM, Ouwehand, W, Watkins, H, Samani, NJ, Saleheen, D, Lawlor, D, Reilly, MP, Hingorani, AD, Talmud, PJ, and Danesh, J. "Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies." Lancet (London, England) 375, no. 9726 (May 2010): 1634-1639. Full Text
  - Velagaleti, RS, Pencina, MJ, Vasan, RS, Benjamin, EJ, Massaro, JM, Pencina, K, and Levy, D. "Cross-sectional relations of lipid concentrations to left ventricular structural attributes." Am J Cardiol 105, no. 9 (May 1, 2010): 1297-1299. Full Text Link to Item
  - Wolongevicz, DM, Zhu, L, Pencina, MJ, Kimokoti, RW, Newby, PK, D'Agostino, RB, and Millen, BE. "Diet quality and obesity in women: the Framingham Nutrition Studies." The British Journal of Nutrition 103, no. 8 (April 2010): 1223-1229. Full Text
  - Steyerberg, EW, and Pencina, MJ. "Reclassification calculations for persons with incomplete follow-up." Ann Intern Med 152, no. 3 (February 2, 2010): 195-196. (Letter) Full Text Link to Item
  - Mitchell, GF, Hwang, S-J, Vasan, RS, Larson, MG, Pencina, MJ, Hamburg, NM, Vita, JA, Levy, D, and Benjamin, EJ. "Arterial stiffness and cardiovascular events: the Framingham Heart Study." Circulation 121, no. 4 (February 2010): 505-511. Full Text
  - Romanens, M, Ackermann, F, Spence, JD, Darioli, R, Rodondi, N, Corti, R, Noll, G, Schwenkglenks, M, and Pencina, M. "Improvement of cardiovascular risk prediction: time to review current knowledge, debates, and fundamentals on how to assess test characteristics." European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 17, no. 1 (February 2010): 18-23. (Review) Full Text
  - Schnabel, RB, Larson, MG, Yamamoto, JF, Sullivan, LM, Pencina, MJ, Meigs, JB, Tofler, GH, Selhub, J, Jacques, PF, Wolf, PA, Magnani, JW, Ellinor, PT, Wang, TJ, Levy, D, Vasan, RS, and Benjamin, EJ. "Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community." Circulation 121, no. 2 (January 4, 2010): 200-207. Full Text
  - Dasta, JF, Kane-Gill, SL, Pencina, M, Shehabi, Y, Bokesch, PM, Wisemandle, W, and Riker, RR. "A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit." Critical Care Medicine 38, no. 2 (2010): 497-503. Full Text
  - Howell, MD, Novack, V, Grgurich, P, Soulliard, D, Novack, L, Pencina, M, and Talmor, D. "Iatrogenic gastric acid suppression and the risk of nosocomial Clostridium difficile infection." Archives of Internal Medicine 170, no. 9 (2010): 784-790. Full Text
  - Lam, CSP, Liu, X, Yang, Q, Larson, MG, Pencina, MJ, Aragam, J, Redfield, MM, Benjamin, EJ, and Vasan, RS. "Familial aggregation of left ventricular geometry and association with parental heart failure: The Framingham Heart Study." Circulation: Cardiovascular Genetics 3, no. 6 (2010): 592-598. Full Text
  - Lopez, JJ, Keyes, MJ, Nathan, S, Piana, R, Pencina, M, Dhar, G, Marso, S, Rao, S, Shammo, S, Marquardt, W, Cohen, DJ, and Kleiman, NS. "Rapid adoption of drug-eluting stents: Clinical practices and outcomes from the early drug-eluting stent era." American Heart Journal 160, no. 4 (2010): 767-774.e1. Full Text
  - Mauri, L, Kereiakes, DJ, Normand, S-LT, Wiviott, SD, Cohen, DJ, Holmes, DR, Bangalore, S, Cutlip, DE, Pencina, M, and Massaro, JM. "Rationale and design of the dual antiplatelet therapy study, a prospective, multicenter, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy in subjects undergoing percutaneous coronary intervention with either drug-eluting stent or bare metal stent placement for the treatment of coronary artery lesions." American Heart Journal 160, no. 6 (2010): 1035-1041.e1. Full Text
  - Novack, V, Nguyen, MC, Rooney, M, Chacko, R, Novack, L, Pencina, M, Apruzzese, P, Mauri, L, Cohen, SA, Moses, J, Leon, MB, and Cutlip, DE. "Effect of coronary target lesion revascularization on late cardiac events after insertion of sirolimus-eluting or bare metal stents." American Journal of Cardiology 106, no. 6 (2010): 774-779. Full Text
  - Novack, V, Pencina, M, Zahger, D, Fuchs, L, Nevzorov, R, Jotkowitz, A, and Porath, A. "Routine laboratory results and thirty day and one-year mortality risk following hospitalization with acute decompensated heart failure." PLoS ONE 5, no. 8 (2010). Full Text
  - Sofat, R, Hingorani, AD, Smeeth, L, Humphries, SE, Talmud, PJ, Cooper, J, Shah, T, Sandhu, MS, Ricketts, SL, Boekholdt, SM, Wareham, N, Khaw, KT, Kumari, M, Kivimaki, M, Marmot, M, Asselbergs, FW, Harst, PVD, Dullaart, RPF, Navis, G, Veldhuisen, DJV, Gilst, WHV, Thompson, JF, McCaskie, P, Palmer, LJ, Arca, M, Quagliarini, F, Gaudio, C, Cambien, F, Nicaud, V, Poirer, O, Gudnason, V, Isaacs, A, Witteman, JCM, Duijn, CMV, Pencina, M, Vasan, RS, D'Agostino, RB, Ordovas, J, Li, TY, and Kakko, S et al. "Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms." Circulation 121, no. 1 (2010): 52-62. Full Text
  - Steyerberg, EW, Vickers, AJ, Cook, NR, Gerds, T, Gonen, M, Obuchowski, N, Pencina, MJ, and Kattan, MW. "Assessing the performance of prediction models: a framework for traditional and novel measures." Epidemiology (Cambridge, Mass.) 21, no. 1 (January 2010): 128-138. Full Text
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  - Millen, BE, Quatromoni, PA, Pencina, M, Kimokoti, R, Nam, B-H, Cobain, S, Kozak, W, Appugliese, DP, Ordovas, J, and D'Agostino, RB. "Unique dietary patterns and chronic disease risk profiles of adult men: The Framingham nutrition studies." Journal of the American Dietetic Association 105, no. 11 (2005): 1723-1734. Full Text
  - Sonnenberg, L, Pencina, M, Kimokoti, R, Quatromoni, P, Nam, B-H, D'Agostino, R, Meigs, JB, Ordovas, J, Cobain, M, and Millen, B. "Dietary patterns and the metabolic syndrome in obese and non-obese framingham women." Obesity Research 13, no. 1 (2005): 153-162.
  - Dhingra, R, Pencina, MJ, Benjamin, EJ, Levy, D, Larson, MG, Meigs, JB, Rifai, N, D'Agostino, RB, and Vasan, RS. "Cross-sectional relations of urinary sodium excretion to cardiac structure and hypertrophy. The Framingham Heart Study." American Journal of Hypertension 17, no. 10 (October 2004): 891-896. Full Text
  - Pencina, MJ, and D'Agostino, RB. "Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation." Statistics in Medicine 23, no. 13 (July 2004): 2109-2123. Full Text

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