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Miles Berger

Adjunct Associate Professor in the Department of Anesthesiology
Anesthesiology, Neuroanesthesia
DUMC Box 3094, Durham, NC 27710
201 Trent Drive, 4317 Duke South, Orange Zone, Durham, NC 27710

Selected Grants


Brain Vulnerability in Delirium and Alzheimer's Disease and Related Dementias: Intersection of Polygenic Risk and Inflammation

ResearchPrincipal Investigator · Awarded by Beth Israel Deaconess Medical Center · 2023 - 2027

CSF Proteomic Studies of APOE4 copy number-dependent effects on the Complement Pathway

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2022 - 2027

Integrated Training in Anesthesiology Research

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1996 - 2026

Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Behavior and Physiology in Aging

Inst. Training Prgm or CMEMentor · Awarded by National Institute on Aging · 2015 - 2025

The Role of the Aging Brain-Heart-Immune Axis in Postoperative Delirium

ResearchMentor · Awarded by National Institutes of Health · 2022 - 2025

Pathogenesis of Neuroinflammation and Neurocognitive Impairment In HIV-infected Young Adult Cannabis Users

ResearchCollaborator · Awarded by National Institutes of Health · 2019 - 2025

FAER GEMSSTAR Supplement (rolling deadline)

ResearchMentor · Awarded by Foundation for Anesthesia Education and Research · 2023 - 2025

Neuroinflammation and Cognitive Outcomes after Spinal versus General Anesthesia in Spine Surgery

ResearchCo Investigator · Awarded by AO North America · 2023 - 2025

Geroscience signaling metabolites NAD+ and beta-hydroxybutyrate modulating acute neuroinflammation in delirium

ResearchPrincipal Investigator · Awarded by Buck Institute for Research on Aging · 2020 - 2024

Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative)

ResearchInvestigator · Awarded by National Institutes of Health · 2017 - 2024

A Phase II Study of an ApoE mimetic peptide to reduce Postoperative Delirium, Cognitive Dysfunction after Non-Cardiac Surgery in Older Adults

Clinical TrialPrincipal Investigator · Awarded by Alzheimer's Drug Discovery Foundation · 2018 - 2024

The Association of Blood-brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium

ResearchMentor · Awarded by Foundation for Anesthesia Education and Research · 2021 - 2024

Proteomic Determination of Complement Activation in Postoperative Delirium

ResearchMentor · Awarded by University of Washington · 2023 - 2024

Blood DNA Methylation Biomarkers of Alzheimer's Disease and Postoperative Neurocognitive Disorder

ResearchPrincipal Investigator · Awarded by University of Wisconsin - Madison · 2022 - 2024

The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium

ResearchMentor · Awarded by National Institutes of Health · 2021 - 2024

Validation of EEG-based Predictive Biomarkers of Post-Operative Delirium

ResearchPrincipal Investigator · Awarded by Beth Israel Deaconess Medical Center · 2023 - 2023

Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2023

Proteomic Determination of APOE4-induced Neuroinflammation in the Pathogenesis of Alzheimer's Disease

ResearchPrincipal Investigator · Awarded by Ruth K. Broad Biomedical Research Foundation · 2020 - 2022

The Role of MCP1 and monocyte activation within the Central Nervous System in Human Postoperative Cognitive Dysfunction and Delirium

ResearchPrincipal Investigator · Awarded by Society for Neuroscience in Anesthesiology and Critical Care · 2016 - 2022

A High-Performance 3T MRI for Brain Imaging

EquipmentMinor User · Awarded by National Institutes of Health · 2021 - 2022

The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium

ResearchMentor · Awarded by Society for Neuroscience in Anesthesiology and Critical Care · 2020 - 2021

A Systems Biology Approach to HIV-associated Neurocognitive Impairment: Role of Drug Abuse and Neuroinflammation

ResearchCollaborator · Awarded by National Institutes of Health · 2016 - 2021

The Role of Obstructive Sleep Apnea in Neuroinflammation and Postoperative Cognitive Dysfunction

FellowshipMentor · Awarded by Foundation for Anesthesia Education and Research · 2019 - 2021

2015 Dennis W. Jahnigen Career Development/GEMSSTAR Program

ResearchPrincipal Investigator · Awarded by American Geriatrics Society · 2015 - 2020

The Significance of Perioperative Changes in CSF tau levels in the Elderly

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2018

The trajectory and significance of perioperative changes in AD biomarkers

ResearchPrincipal Investigator · Awarded by International Anesthesia Research Society · 2014 - 2018

Educating Anesthesia Residents to Improve Perioperative Care for the Elderly

ResearchPrincipal Investigator · Awarded by American Geriatrics Society · 2015 - 2017

Effect of Isoflurane Versus Propofol Anesthesia on Alzheimer's Disease CSF Markers

Clinical TrialPrincipal Investigator · Awarded by Minnetronix, Inc · 2014 - 2016

External Relationships


  • American Society of Anesthesiologists
  • Masimo Corp.
  • Private consulting income from individual legal cases related to postoperative neurologic and cognitive function, one in florida a few years ago, one in Michigan, and one additional one. in the last year
  • Society for Neuroscience in Anesthesia and Critical Care

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.