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Mohamad Abdul Mikati

Wilburt C. Davison Distinguished Professor
Pediatrics, Neurology
Box 3936 Med Ctr, Durham, NC 27710
315 Trent Drive, Hanes House, Suite 345, Durham, NC 27710

Research Interests


Neurophysiology and virus mediated gene therapy of knock in mouse model of ATP1A3 mutation 
Natural history, therapy and clinical manifestations of Alternating Hemiplegia of Childhood
Clinical manifestations and therapy of pediatric status epilepticus
Genetic aspects and therapy of pediatric epilepsy

Selected Grants


An integrated and diverse genomic medicine program for undiagnosed diseases

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2028

The role of the sodium potassium ATPase type alpha-3 subunit in sudden cardiac arrest

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027

Gene Therapy of ATP1A3 Related Disease

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2023 - 2025

La Marato de TV3 Foundation: TREAT-AHC, Identification of compounds for the treatment of Alternating Hemiplegia of Childhood by drug repositioning

ResearchPrincipal Investigator · Awarded by Catholic University of the Sacred Heart · 2022 - 2024

Postdoctoral Training in Genomic Medicine Research

Inst. Training Prgm or CMECo-Mentor · Awarded by National Institutes of Health · 2017 - 2023

Pediatric Status Epilepticus Research Group

ResearchPrincipal Investigator · Awarded by Boston Children's Hospital · 2016 - 2020

ATPA2 Research Project

ResearchPrincipal Investigator · Awarded by Cure AHC · 2017 - 2020

The role of inhibitory neurons in microcephaly and seizure caused by Asparagine synthetase (ASNS) deficiency

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2017 - 2019

Catastrophic outcomes in the AHC knock-in mouse models D801 N and E815K for ACH

ResearchPrincipal Investigator · Awarded by Cure AHC · 2016 - 2018

Pathophysiology of the AHC Knock-in Mouse Model

ResearchPrincipal Investigator · Awarded by Cure AHC · 2015 - 2015

External Relationships


  • UCB Pharma

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.