Current Appointments & Affiliations
Assistant Professor in Surgery
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Recent Publications
Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants.
Journal Article Journal of virology · December 2023 ImportanceMultiple SARS-CoV-2 variants of concern have emerged and caused a significant number of infections and deaths worldwide. These variants of concern contain mutations that might significantly affect antigen-targeting by antibodies. It is t ... Full text CiteMolecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Journal Article Cell Rep · November 28, 2023 IGHV3-33-encoded antibodies are prevalent in the human humoral response against the Plasmodium falciparum circumsporozoite protein (PfCSP). Among VH3-33 antibodies, cross-reactivity between PfCSP major repeat (NANP), minor (NVDP), and junctional (NPDP) mot ... Full text Link to item CiteParameter estimation and identifiability analysis for a bivalent analyte model of monoclonal antibody-antigen binding.
Journal Article Anal Biochem · October 15, 2023 Surface plasmon resonance (SPR) is an extensively used technique to characterize antigen-antibody interactions. Affinity measurements by SPR typically involve testing the binding of antigen in solution to monoclonal antibodies (mAbs) immobilized on a chip ... Full text Link to item CiteRecent Grants
Nonhuman Primate Core-Option 6
ResearchInvestigator · Awarded by National Institutes of Health · 2025 - 2032Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029BNT165-02
ResearchInvestigator · Awarded by BioNTech SE · 2025 - 2028View All Grants
Education, Training & Certifications
Jadavpur University (India) ·
2000
Ph.D.
Bharathidasan University (India) ·
1994
M.S.
Bharathidasan University (India) ·
1992
B.S.