Research Interests
My research interests are in the Biophysical Immunology area. We use biophysical techniques and concepts to study antibody features. Our group is engaged in antibody dynamics work to examine vaccine elicited antibodies-antigen interactions aimed to accelerate progress in combating and eradicating diseases of global health importance. Our team uses Biolayer Interferometry (BLI), High Throughput Surface Plasmon Resonance imaging (SPRi) and Isothermal Titration Calorimetry (ITC) besides optical spectroscopy techniques to address questions related to epitope recognition by monoclonal and polyclonal antibodies that are protective against infection by pathogens.
Selected Grants
Antibody Dynamics for BNT165b1
ResearchAssistant Research Professor · Awarded by BioNTech SE · 2023 - 2025CoVPN 5001 A Prospective Study of Acute Immune Responses to SARS-CoV-2 Infection
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2024CIVICS Component A - Option 4
ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2024CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2024HVTN Supplement 2022
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2023Antibody Dynamics for BNT165b1
ResearchAssistant Research Professor · Awarded by BioNTech SE · 2023 - 2025CoVPN 5001 A Prospective Study of Acute Immune Responses to SARS-CoV-2 Infection
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2024CIVICS Component A - Option 4
ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2024CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2024HVTN Supplement 2022
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2023CoVPN 3001 A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2023HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2022 - 2023CoVPN 3005: Efficacy, Immunogenicity, and Safety of Two SARS-CoV-2 Recombinant Protein Vaccines with Adjuvant in Adults 18 Years of Age and Older
ResearchInvestigator · Awarded by Seattle Cancer Care Alliance · 2022 - 2022CoVPN 3003 A Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older
ResearchInvestigator · Awarded by Seattle Cancer Care Alliance · 2022 - 2022HVTN TB Supplement
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Center · 2021 - 2022CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Research Center · 2020 - 2022HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Research Center · 2020 - 2022Protocol Development Assays
ResearchResearch Scientist · Awarded by Fred Hutchinson Cancer Research Center · 2019 - 2020HVTN TB Correlates Pilot Studies Supplement
ResearchScientist · Awarded by Fred Hutchinson Cancer Research Center · 2019 - 2019HVTN Laboratory Center: HVTN 118
ResearchResearch Scientist · Awarded by Fred Hutchinson Cancer Research Center · 2017 - 2018HVTN Laboratory Center: HVTN 117
ResearchResearch Scientist · Awarded by Fred Hutchinson Cancer Research Center · 2017 - 2018HVTN - A004
ResearchResearch Scientist · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2018HIV Vaccine Trials Network: LC P5 PF
ResearchResearch Scientist · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2018External Relationships
- Biophysical Society
- Indian Biophysical Society
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.