My research is broadly focused on elucidating the complex interactions that exist between the host microbiome and exogenous pathogens that cause infections in children. We have several ongoing projects evaluating: 1) the impact of the upper respiratory microbiome on the risk of colonization and invasion by bacterial respiratory pathogens among infants in Botswana; 2) associations between the gut microbiome of pediatric stem cell transplant recipients and the risk of infections (bloodstream infection, C. difficile infection) and graft-versus-host disease; and 3) the role of the gut and respiratory microbiomes in mediating COVID-19 infection susceptibility and disease severity in children. Ultimately, I aim to develop strategies that use targeted modification of the microbiome for the prevention of infections in children.
Current Appointments & Affiliations
Associate Research Professor of Global Health · 2021 - Present Duke Global Health Institute, University Institutes and Centers
Associate Research Professor in Molecular Genetics and Microbiology · 2023 - Present Molecular Genetics and Microbiology, Basic Science Departments
Education, Training & Certifications
Harvard Medical School · 2007 M.D.
Harvard University · 2007 M.P.H.